Production of recombinant human factor viiic
Номер патента: NZ229662A
Опубликовано: 28-05-1991
Автор(ы): Chikateru Nozaki, Hiroshi Yonemura, Junichi Miyazaki, Ken-Ichi Yamamura, Masatake Araki, Takashi Sugiyama
Принадлежит: Chemo Sero Therapeut Res Inst, Teijin Ltd
Опубликовано: 28-05-1991
Автор(ы): Chikateru Nozaki, Hiroshi Yonemura, Junichi Miyazaki, Ken-Ichi Yamamura, Masatake Araki, Takashi Sugiyama
Принадлежит: Chemo Sero Therapeut Res Inst, Teijin Ltd
Реферат: A plasmid for the expression of a protein having the biological activity of human factor VIII:C is described, which comprises a chicken beta -actin promoter or a derivative thereof and downstream of the promoter a gene coding for said protein having the biological activity of human factor VIII:C. Furthermore, the corresponding transformed microoganisms and processes for the production of a protein having the biological activity of human VIII:C are described. The plasmids allow the production of protein having the biological activity of human factor VIII:C with a high efficiency in an industrial scale.
Serum-free stable transfection and production of recombinant human proteins in human cell lines
Номер патента: US09796986B2. Автор: Cathleen Wegmann,Haiyan Ding,Carola Schroeder. Владелец: Octapharma AG. Дата публикации: 2017-10-24.