Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants
Номер патента: EP1831349A2
Опубликовано: 12-09-2007
Автор(ы): James C. Newbold, Lyle M. Rode
Принадлежит: Sage Biosciences Inc
Опубликовано: 12-09-2007
Автор(ы): James C. Newbold, Lyle M. Rode
Принадлежит: Sage Biosciences Inc
Реферат: Methods for increasing the resistance to rumen inactivation of a cultured Gram positive bacteria strain useful for gastrointestinal delivery of bioactive compounds to ruminants, which includes the steps of growing a culture of the bacteria strain through at least one passage in a growth medium containing an amount of lysozyme effective to induce the growth of bacterial cell walls resistant to protozoal predation; and recovering the bacteria strain from the lysozyme-containing medium. Rumen-bypass feed supplements produced by the inventive method are also disclosed, as well as methods for supplementing the diet of a ruminant with the rumen bypass feed supplements and an in vitro method for evaluating the resistance of Gram positive bacteria strains to rumen inactivation in vivo.
Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants
Номер патента: CA2590719A1. Автор: Lyle M. Rode,C. James Newbold. Владелец: Sage Biosciences Inc.. Дата публикации: 2006-08-31.