Systems and methods for spatial reference sequencing
Опубликовано: 28-02-2024
Автор(ы): Daniel Mazur, Florian OBERSTRASS, Gilad Almogy, Ron Saar DOVER, Zohar SHIPONY
Принадлежит: Ultima Genomics Inc
Реферат: Provided herein are methods, systems, compositions, and kits that can determine spatial information between a plurality of analytes in a sample by tagging such analytes with tags, where identities and/or locations of such tags are previously unknown prior to tagging. Each of a plurality of analyte sequences may be tagged with multiple spatial tags, such that each analyte sequence is associated with a set of two or more spatial tags. The sets of spatial tags may be analyzed to generate a map of analyte sequences. The map may comprise information about the respective absolute positions of each of a set of sequences with respect to a reference sequence. The map may comprise information about the respective probability cloud (or likely location) of each of a set of sequences with respect to a reference sequence.
De-crosslinking compounds and methods of use for spatial analysis
Номер патента: US20230287475A1. Автор: James Michael CHELL,Meiliana TJANDRA,Joshua DELANEY,Aleksandra JUREK,Rapolas SPALINSKAS. Владелец: 10X Genomics Inc. Дата публикации: 2023-09-14.