Recombinant tert-encoding viral genomes and vectors
Номер патента: EP4337780A1
Опубликовано: 20-03-2024
Автор(ы): Estefanía CASANA LORENTE, Maria BLASCO, Maria Fátima BOSCH TUBERT, Miquel Garcia Martinez, Paula MARTINEZ, Verónica Jiménez Cenzano
Принадлежит: Fundacion del Sector Publico Estatal Centro Nacional de Investigaciones Oncologicas Carlos III FSP CNIO, Telomere Therapeutics Sl, Universitat Autonoma de Barcelona UAB
Опубликовано: 20-03-2024
Автор(ы): Estefanía CASANA LORENTE, Maria BLASCO, Maria Fátima BOSCH TUBERT, Miquel Garcia Martinez, Paula MARTINEZ, Verónica Jiménez Cenzano
Принадлежит: Fundacion del Sector Publico Estatal Centro Nacional de Investigaciones Oncologicas Carlos III FSP CNIO, Telomere Therapeutics Sl, Universitat Autonoma de Barcelona UAB
Реферат: Described herein are recombinant viral genomes comprising a nucleotide sequence encoding a telomerase reverse transcriptase (TERT) operably linked to a tissue-specific and/or organ-specific promoter. Aspects described herein may be used in the treatment of conditions associated with shortened telomere length, such as pulmonary fibrosis, myocardial infarction and conditions associated therewith.
Recombinant tert-encoding viral genomes and vectors
Номер патента: CA3219795A1. Автор: Verónica Jiménez Cenzano,Maria Fátima BOSCH TUBERT,Miquel Garcia Martinez,Estefanía CASANA LORENTE,Maria BLASCO,Paula MARTINEZ. Владелец: Telomere Therapeutics Sl. Дата публикации: 2022-11-17.