T cell antigen receptor, multimeric complex thereof and preparation method and use thereof
Номер патента: CA3184695A1
Опубликовано: 06-01-2022
Автор(ы): Daosheng HUANG, Fang Liu, Guangna LIU, HUA Chen, Lei Lei, Lemei JIA, XIN Lin, Xueqiang ZHAO
Принадлежит: Bristar Immunotech Ltd, TSINGHUA UNIVERSITY
Опубликовано: 06-01-2022
Автор(ы): Daosheng HUANG, Fang Liu, Guangna LIU, HUA Chen, Lei Lei, Lemei JIA, XIN Lin, Xueqiang ZHAO
Принадлежит: Bristar Immunotech Ltd, TSINGHUA UNIVERSITY
Реферат: A T cell antigen receptor, an immune cell for expressing the T cell antigen receptor (TCR) and a preparation method and use thereof. The TCR disclosed in the present invention can be specifically activated by virus antigen peptide presenting cells, so that the release level of extracellular cytokines IFN? and IL2 and the release amount of lactate dehydrogenase are improved, and target cells are significantly killed.
Bispecific antibodies to MOSPD2 and T cell- or NK cell-specific molecules
Номер патента: AU2019235652B2. Автор: Itzhak Mendel,Eyal Breitbart,Yaniv Salem. Владелец: Immunewalk Therapeutics Inc. Дата публикации: 2024-07-25.