Method for increasing the throughput of nmr spectrometers
Номер патента: EP1275011A1
Опубликовано: 15-01-2003
Автор(ы): Alfred Ross, Götz SCHLOTTERBECK, Hans Senn
Принадлежит: F Hoffmann La Roche AG
Опубликовано: 15-01-2003
Автор(ы): Alfred Ross, Götz SCHLOTTERBECK, Hans Senn
Принадлежит: F Hoffmann La Roche AG
Реферат: For simultaneously determining the analytical NMR spectra of a number of samples placed suitably arranged in the measuring site of an NMR measuring apparatus, spatially and timely varying magnetic fields are used. The resulting signals are spatially resolved by a suited processing, for example Fourier transform. Surprisingly, from these signals, analytical NMRs of high resolution can be obtained for each sample. The method can be applied to two-dimensional arrangements of samples, for example a bundle of capillaries (1, 10) imitating a conventional NMR sample tube or a well plate (18), or three-dimensional arrangements, for example stacks of well plates (18). The method allows the determination of NMR spectra for analysis or for comparison with anterior spectra for long time behavior studies and quality assessment with only a fraction of time needed for measuring the samples individually.
Method for increasing the throughput of nmr spectrometers
Номер патента: WO2001079874A1. Автор: Alfred Ross,Hans Senn,Götz SCHLOTTERBECK. Владелец: F. Hoffmann-La Roche AG. Дата публикации: 2001-10-25.