Heterodimeric tetravalency and specificity antibody compositions and uses thereof
Номер патента: EP3902834A1
Опубликовано: 03-11-2021
Автор(ы): Brian SANTICH, Morgan HUSE, Nai-Kong V. Cheung
Принадлежит: Memorial Sloan Kettering Cancer Center
Опубликовано: 03-11-2021
Автор(ы): Brian SANTICH, Morgan HUSE, Nai-Kong V. Cheung
Принадлежит: Memorial Sloan Kettering Cancer Center
Реферат: The present disclosure relates generally to immunoglobulin-related compositions ( e.g ., heterodimeric trivalent/tetravalent multispecific antibodies) that specifically bind to three or four distinct target antigens. The immunoglobulin-related compositions described herein are useful in methods for detecting and treating cancer in a subject in need thereof.
Multi-specific antibodies and methods of making and using thereof
Номер патента: US20230322920A1. Автор: Yu Liang,Brian Kovacevich,Dong Xia,Ole Olsen,Zeren Gao,Yi Zhu,David JELLYMAN,Katrina BYKOVA,Bill Brady,Blair RENSHAW,Anne-Marie K. ROUSSEAU. Владелец: Systimmune Inc. Дата публикации: 2023-10-12.