Diagnostic assays using bacterial quorum sensing signals
Номер патента: EP3810794A1
Опубликовано: 28-04-2021
Автор(ы): Angel A. RIVERA, Maria Margaret NAGY
Принадлежит: Quorum X Diagnostics Inc
Опубликовано: 28-04-2021
Автор(ы): Angel A. RIVERA, Maria Margaret NAGY
Принадлежит: Quorum X Diagnostics Inc
Реферат: Disclosed are methods, systems, devices, and kits for diagnosing and/or monitoring a bacterial infection in a subject in need thereof. The methods, systems, devices, and kits are useful for identifying causative bacteria, such as Pseudomonas aeruginosa , by, for example, detecting the presence of one or more quorum sensing (QS) molecules associated with the bacteria. For P. aeruginosa these can include C4 homoserine lactone and/or C12 homoserine lactone. The methods, systems, devices, and kits can further include steps or features for obtaining diagnosis results and/or prescribing an antibiotic for the subject if, for example, the presence and/or increased levels of the QS molecule are detected. The methods, systems, devices, and kits can further include steps or features guiding a treatment regimen, such as whether to initiate or continue treatment of a bacterial infection caused by bacteria, such as P. aeruginosa, detected using the disclosed methods, systems, devices, and kits.
Diagnostic assays using bacterial quorum sensing signals
Номер патента: WO2019246621A1. Автор: Maria Margaret NAGY,Angel A. RIVERA. Владелец: Quorum X Diagnostics, Inc.. Дата публикации: 2019-12-26.