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Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Применить Всего найдено 37259. Отображено 200.
19-07-2023 дата публикации

Способ получения релаксирующей, седативной биологически активной фармакологической композиции, применяемой в вечернее время суток для профилактики дисфункций центральной нервной системы

Номер: RU2800280C2

Изобретение относится к фармацевтической промышленности, а именно к способу получения релаксирующей, седативной биологически активной фармакологической композиции. Способ получения релаксирующей, седативной биологически активной фармакологической композиции, характеризующийся тем, что растительное сырье: шишкоягоды можжевельника обыкновенного Juniperus communis L, соцветия ромашки аптечной Matricaria chamomilla, корнеплоды свеклы обыкновенной Beta vulgaris, шишки хмеля Humulus lupulus L, соцветия и листья таволги Filipendula, корневища пиона уклоняющегося Paeonia anomala, листья дуба черешчатого Qvercus robur берут в равных по массе пропорциях, по 50 г каждого, и экстрагируют этиловым спиртом из картофеля, предварительно нагретым до 60 градусов по Цельсию, объемом 3500 мл, в течение 3 часов, сливают концентрат в количестве 3000 мл и разводят его талой водой до 55%. Вышеописанный способ позволяет получить композицию с выраженными релаксирующими, седативными свойствами. 2 ил.,1 пр.

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18-01-2017 дата публикации

Применение экстрактов лабазника (Filipendula) для лечения и профилактики хронической боли

Номер: RU2608442C2

Настоящее изобретение относится к фармацевтической промышленности, а именно к средству для лечения хронической боли без распознаваемых органических причин. Экстракт из лабазника вязолистного (Filipendula ulmaria) предназначен для лечения хронической боли без распознаваемых органических причин, причем экстракт получают путем экстракции надземных частей лабазника вязолистного (Filipendula ulmaria) 50-70%-ным этанолом. Лекарственное средство для лечения хронической боли без распознаваемых органических причин. Вышеописанные средства эффективны для лечения хронической боли без распознаваемых органических причин. 2 н.п. ф-лы, 2 ил., 2 пр.

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27-03-2016 дата публикации

СПОСОБ ПОЛУЧЕНИЯ НАНОКАПСУЛ ФЛАВОНОИДОВ ШИПОВНИКА

Номер: RU2578404C2

Изобретение относится к способу получения нанокапсул флавоноидов шиповника. Указанный способ характеризуется тем, что флавоноиды шиповника диспергируют в суспензию альгината натрия в бензоле в присутствии препарата Е472с при перемешивании, затем приливают хлороформ, полученный осадок отфильтровывают и сушат при комнатной температуре, при этом флавоноиды шиповника и альгинат натрия берут в соотношении 1:3, 1:1 или 5:1. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул флавоноидов шиповника, а также высокий выход по массе. 1 ил., 4 пр.

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27-06-2014 дата публикации

ЛЕКАРСТВЕННАЯ КОМПОЗИЦИЯ ДЛЯ ЛЕЧЕНИЯ БРОНХИТА И СПОСОБ ЕЕ ПОЛУЧЕНИЯ

Номер: RU2520745C2

Изобретение относится к фармацевтической промышленности, в частности к фармацевтической композиции для лечения бронхита. Фармацевтическая композиция для лечения бронхита содержит порошок SCUTELLARIAE RADIX; эфирное масло, полученное из смеси растений CITRI RETICULATAE PERICARPIUM и CINNAMOMI RAMULUS; сконцентрированный водный экстракт, полученный изтравяного остатка, оставшегося после получения эфирного масла, и смеси растений, состоящей из ATRACTYLODIS MACROCEPHALAE RHIZOMA, PORIA, GLYCYRRHIZAE RADIX ET RHIZOMA, FARFARAE FLOS, FORSYTHIAE FRUCTUS; сконцентрированный этанольный экстракт из PINELLIAE RHIZOMA, PERILLAE FRUCTUS, SINAPIS SEMEN, RAPHANI SEMEN, ASTERIS RADIX ET RHIZOMA, HOUTTUYNIAE HERBA, ARMENIACAE SEMEN AMARUM.Заявленная фармацевтическая композиция эффективна в устранении мокроты, облегчении кашля, ослаблении астмы, а также сопротивлении воспалению, и оказывает хороший лечебный эффект при лечении бронхита. 10 з.п. ф-лы, 15 табл., 12 пр.

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05-02-2021 дата публикации

Комбинированная полимерная плёнка с биологически активными веществами сабельника болотного, мирамистином и пиридоксином

Номер: RU2742381C2

Изобретение относится к фармацевтической промышленности, а именно к способу получения комбинированной полимерной пленки с биологически активными веществами сабельника болотного, мирамистином и пиридоксином. Способ получения комбинированной полимерной пленки с биологически активными веществами сабельника болотного, мирамистином и пиридоксином, заключающийся в том, что в 15 мл воды очищенной добавляют 7 капель глицерина, 7 мл жидкого спиртового экстракта-концентрата 1:2 корневищ сабельника болотного и 5 мл 0,01% раствора мирамистина, затем смесь нагревают на водяной бане до температуры 70°С, добавляют 0,9 г метилцеллюлозы и 0,45 г поливинилпирролидона, далее смесь гомогенизируют, охлаждают в течение 30 мин при комнатной температуре, а затем выдерживают при 8-10°С в течение 12 ч, после этого добавляют 2 мл 5% раствора пиридоксина (витамина В6), гомогенизируют и оставляют при температуре 8-10°С на 24 ч, далее повторно гомогенизируют смесь, выливают на стандартную стеклянную подложку площадью ...

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25-04-2017 дата публикации

РАСТИТЕЛЬНЫЕ КОМБИНИРОВАННЫЕ ПРЕПАРАТЫ НА ОСНОВЕ КРИОПОРОШКОВ

Номер: RU2617434C2

Изобретение относится к фармацевтической промышленности, а именно к препарату, обладающему диуретическим, и/или антибактериальным, и/или литолитическим действием. Растительный комбинированный препарат, обладающий диуретическим, и/или антибактериальным, и/или литолитическим действием, содержащий криопорошки травы репейничка аптечного и корня шиповника собачьего и вспомогательные вещества. Вышеописанный препарат обладает эффективным диуретическим, и/или антибактериальным, и/или литолитическим действием. 6 з.п. ф-лы, 12 ил., 11 табл.

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31-10-2017 дата публикации

СПОСОБ ПОЛУЧЕНИЯ ЛЕКАРСТВЕННОГО СРЕДСТВА, ОБЛАДАЮЩЕГО ПРОТИВОВОСПАЛИТЕЛЬНЫМ ДЕЙСТВИЕМ

Номер: RU2634570C1

Изобретение относится к фармацевтической промышленности, а именно к способу получения средства, обладающего противовоспалительным действием. Способ получения лекарственного средства, обладающего противовоспалительным действием, представляющего собой сухой экстракт, полученный путем трехкратной экстракции растительного сырья: плодов граната, коры корицы, плодов кардамона, плодов перца длинного, корня имбиря, плодов яблони, корней девясила, плодов кориандра, плодов солодки, которое измельчают до размера частиц диаметром 1 мм и экстрагируют 50% этиловым спиртом в соотношении сырье : экстрагент, равном 1:(14-16), при температуре 60°C и постоянном перемешивании, при этом 1-ю и 2-ю экстракцию проводят в течение 60 минут, 3-ю экстракцию в течение 30 минут, объединенные извлечения упаривают до 1/3 первоначального объема и очищают сепарированием, очищенный экстракт доупаривают до 1/5 первоначального объема, высушивают в вакуумной сушилке при температуре 60°C в течение 8 ч, измельчают на мельнице ...

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13-11-2017 дата публикации

Фитокомпозиция для гигиены полости рта

Номер: RU2635509C1

Изобретение относится к медицине, а именно к стоматологии, и может быть использовано для ухода за зубами и полостью рта, для гигиены полости рта, в частности, у онкологических больных. Фитокомпозиция для гигиены полости рта у онкологических больных, страдающих сопутствующими заболеваниями зубов и десен и прошедших химио- и лучевую терапию, характеризуется тем, что представляет собой порошок измельченных лекарственных растений: травы мяты перечной, травы череды, травы чистотела, цветов, листьев и стебля эхинацеи, травы тысячелистника, цветов календулы, цветов пижмы, цветов лабазника, корня аира, листа подорожника, взятые в равных соотношениях 1:1, при этом порошок получен методом дробного измельчения до частиц, проходящих сквозь сито 0,5 мм. Фитокомпозиция может быть выполнена в виде разовой дозы порошка массой 3 г. Порошок может применяться в виде водного настоя, который получают при заливании 3 г порошка 200 мл кипятка. Водный настой может применяться в виде порционных кубиков льда. Порошок ...

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29-03-2018 дата публикации

Номер: RU2016100341A3
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28-11-2022 дата публикации

Способ ускорения ранозаживления и формирования слизистой оболочки протезного ложа

Номер: RU2784519C1

Изобретение относится к области медицины, а именно к стоматологии, и предназначено для ускорения ранозаживления и формирования слизистой оболочки протезного ложа после хирургических вмешательств. Способ включает применение иммедиат протеза для ускорения заживления операционной раны, при этом на базис съемного пластичного протеза в месте контакта с травмированным и воспаленным участком слизистой оболочки полости рта или непосредственно на травмированную и воспаленную слизистую оболочку полости рта под протезом наносят 2 раза в день после индивидуальной гигиены полости рта в течение 21 дня экдистероидсодержащую композицию, полученную из: корневища с корнями левзеи сафлоровидной - 2 мас. части; цветков календулы - 1 мас. часть; листа бадана толстолистного - 1 мас. часть; цветков лабазника вязолистного - 1 мас. часть, из которой методом перколяции 40% этиловым спиртом получают настойку (1:5), после чего 10,0 грамм этой настойки инкорпорируют в 90,0 грамм основы. Комбинация иммедиат протеза ...

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20-09-2009 дата публикации

ЛЕКАРСТВЕННОЕ СРЕДСТВО, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ИНГИБИТОР РОСТА HELICOBACTER PYLORI И СПОСОБ ПРОВЕДЕНИЯ АНТИХЕЛИКОБАКТЕРНОЙ ТЕРАПИИ

Номер: RU2367458C1

Группа изобретений относится к фармацевтической промышленности, в частности к средству для ингибирования бактерий рода Helicobacter pylori. Лекарственное средство для ингибирования бактерий рода Helicobacter pylori, представляющее собой хвойную хлорофилло-каротиновую пасту. Фармацевтическая композиция для ингибирования бактерий рода Helicobacter pylori, которая содержит хвойную хлорофилло-каротиновую пасту в терапевтически эффективном количестве и фармацевтически приемлемые носители и/или растворители. Применение хвойной хлорофилло-каротиновой пасты в качестве активного ингредиента фармацевтической композиции для ингибирования бактерий рода Helicobacter pylori. Применение хвойной хлорофилло-каротиновой пасты в качестве ингибитора бактерий рода Helicobacter pylori. Вышеописанное средство и фармацевтическая композиция на основе такого средства эффективно ингибируют бактерии рода Helicobacter pylori. 4 н. и 1 з.п. ф-лы, 4 табл.

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16-01-2023 дата публикации

Средство, обладающее детоксикационной активностью при алкогольной интоксикации

Номер: RU2787997C1

Изобретение относится к области фармацевтики и медицины, а именно к применению водно-спиртового экстракта травы репешка волосистого Agrimonia pilosa, полученного экстракцией исходного растительного сырья на 70%-ном этаноле при последующем высушивании при температуре 40 °С, в качестве средства, обладающего детоксикационным эффектом на центральную нервную систему при алкогольной интоксикации, включающим снижение чувствительности к этаноловому наркозу, сокращение длительности этанолового сна, противотревожное действие. Технический результат заключается в детоксикационной активности на центральную нервную систему водно-спиртового экстракта травы репешка волосистого Agrimonia pilosa при алкогольной интоксикации. 7 табл., 6 пр.

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27-11-2016 дата публикации

СИРОП ЛАПЧАТКИ БЕЛОЙ

Номер: RU2603466C1

Изобретение относится к химико-фармацевтической промышленности, в частности к сиропу лапчатки белой (Potentilla alba L., сем. Розоцветные - Rosaceae), обладающему антибактериальным действием. Сироп лапчатки белой, обладающий антибактериальным действием, который изготавливают на основе сорбита и водного извлечения, получаемого из корневищ и корней лапчатки белой, при определенных условиях. Вышеописанный сироп обладает эффективным антибактериальным действием, является стабильным. 1 пр., 1 ил.

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10-10-2016 дата публикации

ТАБЛЕТИРОВАННОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО НА ОСНОВЕ ЭКСТРАКТА МАНЖЕТКИ ОБЫКНОВЕННОЙ

Номер: RU2599020C1

Изобретение относится к таблетированному лекарственному средству для лечения синдрома повышенной вязкости крови. Указанное средство включает 6 мас.% густого экстракта манжетки обыкновенной, полученного упариванием спиртовой вытяжки до остаточной влажности 25%, 46,8 мас.% глюкозы, 46,8 мас.% лактозы, 0,1 мас.% стеарата кальция и 5% водный раствор метилцеллюлозы - остальное. Изобретение обеспечивает получение таблеток, обладающих высокой прочностью, высокой стабильностью при хранении и удовлетворяющих требованиям действующей фармакопеи. 2 табл., 1 пр.

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21-01-2021 дата публикации

СБОР ЛЕКАРСТВЕННЫХ РАСТЕНИЙ НООТРОПНОГО ДЕЙСТВИЯ

Номер: RU2740897C1

Изобретение относится к фармацевтической промышленности, а именно к сбору лекарственных растений ноотропного действия. Сбор лекарственных растений, обладающий ноотропным действием, включает листья гинкго билоба, листья бадана толстолистного, траву лабазника вязолистного, корни солодки, плоды боярышника при определенном соотношении компонентов. Вышеописанный сбор обладает выраженным ноотропным действием, в том числе на фоне приема препаратов, снижающих когнитивные функции, и при этом является безопасным при длительном ежедневном применении в терапевтических дозах. 3 табл., 2 пр.

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25-10-2021 дата публикации

Фитокомплекс для профилактики развития игровой зависимости (варианты)

Номер: RU2757952C1

Изобретение относится к фармацевтической промышленности, а именно к фитокомлексам для приготовления настоя для профилактики развития игровой зависимости (варианты). Фитокомплекс для приготовления настоя для профилактики развития игровой зависимости, характеризующийся тем, что содержит цветы, лист и стебель кипрея, цветы красного клевера, корень аира, траву пустырника, цветки и листья таволги, траву мяты, лист березы, лист брусники, цветы бессмертника, цветы липы, корень алтея, корень элеутерококка, корень солодки, плоды шиповника, цветы зверобоя при следующем соотношении 5:3:2:2:1:2:2:2:2:2:2:1:2:2:2 соответственно, для возрастной категории от 7 до 14 лет. Фитокомплекс для приготовления настоя для профилактики развития игровой зависимости, характеризующийся тем, что содержит цветы, лист и стебель кипрея, цветы красного клевера, корень аира, траву пустырника, цветки и листья таволги, траву мяты, лист березы, цветы бессмертника, цветы липы, корень алтея, корень элеутерококка, корень левзеи ...

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26-08-2024 дата публикации

ПРИМЕНЕНИЕ ГАУЛЬТЕРИНА В КАЧЕСТВЕ АНТИДЕПРЕССАНТНОГО СРЕДСТВА

Номер: RU2825385C1

Изобретение относится к фармакологии, а именно к лекарственным средствам, обладающим антидепрессантной активностью. Предложено применение гаультерина в качестве антидепрессантного средства. Изобретение позволяет повысить эффективность лечебного воздействия и исключить возникновение побочных эффектов. 8 з.п. ф-лы, 1 ил., 1 табл., 2 пр.

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27-03-2006 дата публикации

КОМБИНАЦИЯ АКТИВНЫХ ИНГРЕДИЕНТОВ МАСЕЛ, СОДЕРЖАЩИХ W3-ЖИРНЫЕ КИСЛОТЫ, С РАСТИТЕЛЬНЫМИ ЭКСТРАКТАМИ, СОДЕРЖАЩИМИ ПОЛИФЕНОЛЫ, И ИХ ПРИМЕНЕНИЕ

Номер: RU2005130342A
Принадлежит:

... 1. Комбинация активных ингредиентов, включающая, по меньшей мере, одно масло, содержащее W3-жирные кислоты, и, по меньшей мере, один растительный экстракт, содержащий полифенолы, причем растительный экстракт, содержащий полифенолы, представляет собой экстракт из Vitis vinifera. 2. Комбинация активных ингредиентов по п.1, отличающаяся тем, что масло, содержащее W3-жирную кислоту, содержит альфа-линоленовую кислоту. 3. Комбинация активных ингредиентов по п.2, отличающаяся тем, что масло, содержащее W3-жирную кислоту, выбрано из группы, включающей перилловое масло, масло бораго, масло семян вечерней примулы, рыбий жир, льняное масло и масло семян черной смородины. 4. Комбинация активных ингредиентов по любому из пп.1-3, отличающаяся тем, что растительный экстракт, содержащий полифенолы, содержит, по меньшей мере, 15% полифенолов в расчете на вес сухого вещества. 5. Применение комбинации активных ингредиентов по любому из пп.1-4 для лечения, повышения эффективности лечения и для профилактики ...

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10-08-2016 дата публикации

ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ДЛЯ РЕГЕНЕРАЦИИ ПЕЧЕНИ

Номер: RU2015100281A
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... 1. Фармацевтическая композиция для применения в способе для регенерации печени или для улучшения работы печени; причем фармацевтическая композиция содержит витамины В, В(фолиевую кислоту) и Вв следующих суточных дозировках:Вне менее 4 мг, при необходимости не более 500 мг;Вне менее 0,6 мг, при необходимости не выше 15 мг;Вне менее 0,008 мг, при необходимости не выше 4 мг.2. Фармацевтическая композиция для терапевтического применения по пункту 1, причем способ включает в себя ее пероральный прием таким образом, что суточная доза вводимого с ней витамина В(фолиевой кислоты) находится в пределах 0,6-15 мг/сут (1,5-40 RDA) или 0,8-8 мг/сут (2-20 RDA).3. Фармацевтическая композиция для терапевтического применения по пункту 1, причем способ включает в себя ее пероральный прием таким образом, что суточная доза вводимого с ней витамина Внаходится в пределах 0,008-4 мг/сут (3-1700 RDA), или 0,1-1,2 мг/сут (40-500 RDA), или 0,2-1,2 мг/сут (80-500 RDA).4. Фармацевтическая композиция для терапевтического ...

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10-11-2016 дата публикации

КОМБИНАЦИЯ ТРАДИЦИОННОЙ КИТАЙСКОЙ МЕДИЦИНЫ ДЛЯ РЕГУЛЯЦИИ ИММУННОЙ ФУНКЦИИ И СПОСОБ ЕЕ ПОЛУЧЕНИЯ

Номер: RU2015113319A
Принадлежит:

... 1. Композиция традиционной китайской медицины для регуляции иммунитета, отличающаяся тем, что композиция содержит следующие сырьевые материалы, мас.ч.:2. Композиция традиционной китайской медицины по п. 1, отличающаяся тем, что сырьевые материалы представляют собой, мас.ч.: 10-90 мас.ч.3. Композиция традиционной китайской медицины по п. 2, отличающаяся тем, что сырьевые материалымас.ч. представляют собой, мас.ч.:4. Композиция традиционной китайской медицины по п. 1, отличающаяся тем, что 10-50 мас.ч. Bulbus Lilii или экстракта Bulbus Lilii, полученного путем применения фармацевтически общепринятого способа в количестве, эквивалентном количеству сырого Bulbus Lilii, дополнительно добавляют к сырьевым материалам.5. Композиция традиционной китайской медицины по п. 1, отличающаяся тем, что 10-50 мас.ч. порошка из спор Ganoderma и/или масла из спор Ganoderma дополнительно добавляют к сырьевым материалам.6. Композиция традиционной китайской медицины по любому из пп. 1-3, отличающаяся тем, что ...

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20-07-2016 дата публикации

ПРИМЕНЕНИЕ КОМПОЗИЦИИ В ПОЛУЧЕНИИ МЕДИЦИНСКОЙ ПРОДУКЦИИ ИЛИ ЛЕКАРСТВЕННОГО СРЕДСТВА ДЛЯ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ ВЫЗВАННОЙ ЛУЧЕВОЙ И ХИМИОТЕРАПИЕЙ ЛЕЙКОПЕНИИ

Номер: RU2014151160A
Принадлежит:

... 1. Применение композиции, изготовленной из сырьевых материалов, содержащих Ganoderma, Radix Panaris Quinquefolii или Radix Et Rhizoma Ginseng, ферментированный порошок Cordyceps sinensis и/или Cordyceps, в производстве композиции для профилактики и лечения вызванной лучевой терапией или химиотерапией лейкопении.2. Применение по п. 1, при котором сырьевые материалы дополнительно содержат одно или несколько из Flos Rosae Rugosae, порошка спор Ganoderma, масла спор Ganoderma, Radix Pseudostellariae, Folium Radix Ginseng, Codonopsis и Radix Astragali.3. Применение по п. 1, при котором сырьевые материалы содержат от 5 до 200 частей Ganoderma, от 5 до 150 частей Radix Panaris Quinquefolii или Radix Et Rhizoma Ginseng, от 1 до 90 частей ферментированного порошка Cordyceps sinensis и/или от 1 до 120 частей Cordyceps.4. Применение по п. 3, при котором сырьевые материалы представляют собой от 5 до 200 частей Ganoderma, от 5 до 150 частей Radix Panaris Quinquefolii или Radix Et Rhizoma Ginseng, от ...

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14-06-2018 дата публикации

Средство, обладающее антиметастатической активностью и повышающее противометастатическое действие циклофосфана

Номер: RU2657602C1

Изобретение относится к фармацевтической промышленности, а именно к применению средства, обладающего антиметастатической активностью и повышающего противометастатическое действие циклофосфана. Применение жидкого спиртового экстракта плодов аронии черноплоднойполученного методом противоточной 5-ступенчатой реперколяции с законченным циклом измельченных до 0,5-1 мм плодов аронии черноплодной 95%-ным подкисленным этиловым спиртом при комнатной температуре, отстаиванием экстракта при температуре не выше 10°C не менее двух суток, фильтрованием, в качестве средства, обладающего антиметастатической активностью и повышающего противометастатическое действие циклофосфана. Вышеописанное средство обладает выраженной антиметастатической активностью и повышает противометастатическое действие циклофосфана. 1 табл., 1 пр.

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18-02-2020 дата публикации

Способ получения нанокапсул сухого экстракта крапивы

Номер: RU2714489C1

Изобретение относится к области нанотехнологии, медицины, косметики и пищевой промышленности. Способ получения нанокапсул сухого экстракта крапивы характеризуется тем, что сухой экстракт крапивы добавляют в суспензию каппа-каррагинана в гексане в присутствии 0,01 г сложного эфира глицерина с одной-двумя молекулами пищевых жирных кислот и одной-двумя молекулами лимонной кислоты в качестве поверхностно-активного вещества при перемешивании 700 об/мин, далее приливают гексафторбензол, полученную суспензию нанокапсул отфильтровывают и сушат при комнатной температуре, при этом массовое соотношение ядро:оболочка составляет 1:1, 1:2 или 1:3. 3 пр.

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27-04-2015 дата публикации

ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ДЛЯ ЛЕЧЕНИЯ БОЛЕЗНИ ПЕЧЕНИ

Номер: RU2013146602A
Принадлежит:

... 1. Фармацевтическая композиция для замедления прогрессирования гепатоцеллюлярной карциномы (HCC), улучшения функций печени, уменьшения фиброза печени, цирроза печени и воспаления печени, стимуляции регенерации поврежденной печени и/или регрессии фиброза печени, содержащая: проантоцианидин в эффективном количестве, при этом мономерные звенья проантоцианидина имеют следующую формулу:в которой, в случае, когда Rпредставляет собой OCH, Rпредставляет собой OH и Rпредставляет собой H, когда Rпредставляет собой OH, Rпредставляет собой H и Rпредставляет собой H, когда Rпредставляет собой OH, Rпредставляет собой OH и Rпредставляет собой H, или когда Rпредставляет собой OH, Rпредставляет собой OH и Rпредставляет собой OH, и Rпредставляет собой 3-(α)-OH, 3-(β)-OH, 3-(α)-O-сахар или 3-(β)-O-сахар; и фармацевтически приемлемый носитель или соль.2. Фармацевтическая композиция по п. 1, в которой мономерные звенья проантоцианидина связаны друг с другом через образование связи в положениях C4-C8, C4-C6 ...

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27-03-2009 дата публикации

СПОСОБ ПОЛУЧЕНИЯ ПРОАНТОЦИАНИДИНОВОГО ОЛИГОМЕРА

Номер: RU2007135274A
Принадлежит:

... 1. Композиция, содержащая в качестве главного компонента проантоцианидиновый олигомер, к концу которого присоединено вещество, содержащее флороглюциновую кольцевую структуру или резорциновую кольцевую структуру, и молекулярная масса которого уменьшена, которую получают путем нагревания растительных материалов, содержащих проантоцианидиновый полимер, или их экстрактов с веществом, содержащим флороглюциновую кольцевую структуру или резорциновую кольцевую структуру, растением, содержащим такое вещество, или его экстрактом в водном растворе кислоты. 2. Композиция, содержащая в качестве главного компонента проантоцианидиновый олигомер по п.1, в которой растение, содержащее проантоцианидиновый полимер, представляет собой по меньшей мере один вид, выбранный из группы, включающей виноград, сосну, Chamaecyparis obtuse (кипарисовик туполистный), камфарное дерево, восковник восконосный, какао, хурму обыкновенную, банан, хеномелес китайскую, яблоню, боярышник, личи, Myrica rubra (восковница красная ...

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20-08-2013 дата публикации

ТРАДИЦИОННАЯ КИТАЙСКАЯ ЛЕКАРСТВЕННАЯ КОМПОЗИЦИЯ ДЛЯ ЛЕЧЕНИЯ БРОНХИАЛЬНОЙ АСТМЫ И СПОСОБ ЕЕ ИЗГОТОВЛЕНИЯ

Номер: RU2011146425A
Принадлежит:

... 1. Композиция традиционного китайского лекарственного средства для лечения бронхиальной астмы, которая изготовлена из следующего состава сырьевых медицинских материалов:40-90 частей травы эфедры (Herba Ephedrae),136-300 частей коры шелковицы (Cortex Mori),146-300 частей дождевого червя (Lumbricus),46-151 частей семян гингко (Semen Ginkgo),46-151 частей цветов мать-и-мачехи (Flos Farfarae),46-151 частей корневища пинеллии (Rhizoma Pinelliae),46-151 частей плодов периллы (Fructus Perillae),146-300 частей корня пиона красного (Radix Paeoniae Rubra),46-151 частей семян абрикоса горького (Semen Armeniacae Amarum),46-151 частей корня шлемника (Radix Scutellariae),46-151 частей периостракума цикады (Periostracum Cicadae),146-300 частей травы гуттуинии (Herba Houttuyniae),146-300 частей корня трихозанта (Radix Trichosanthis) и46-151 частей плодов форзиции (Fructus Forsythiae).2. Композиция по п.1, которая готовится из следующего состава сырьевых медицинских материалов:50-76 частей травы эфедры ...

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11-01-2024 дата публикации

Способ количественного определения суммы флавоноидов в траве лабазника вязолистного

Номер: RU2811264C1

Изобретение относится к области химии и фармацевтики, а именно к способу количественного определения суммы флавоноидов в траве лабазника вязолистного. Способ количественного определения суммы флавоноидов в траве лабазника вязолистного, включающий однократную экстракцию воздушно-сухого сырья органическим растворителем с последующей пробоподготовкой и определением оптической плотности методом дифференциальной спектрофотометрии, отличающийся тем, что экстракцию сырья осуществляют этиловым спиртом в концентрации 40% в соотношении «сырье-экстрагент» - 1 г сырья к 50 мл спирта, время экстракции на кипящей водяной бане составляет 90 минут, степень измельчения сырья – 1 мм; количественное определение суммы флавоноидов в траве лабазника вязолистного проводят при длине волны 412±2 нм в пересчете на рутин; содержание суммы флавоноидов Х, выраженное в процентах, в пересчете на стандартный образец рутина вычисляют по формуле: , где в числителе: Dx – оптическая плотность исследуемого раствора; 50 – объём ...

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05-07-2007 дата публикации

Pharmaceutical preparation, useful as soothing agent e.g. against cough, comprises combination of at least two mucilaginous drugs, preferably combination of iceland moss (Lichen islandicus) and mucilaginous drug

Номер: DE202006008541U1
Автор:

Pharmaceutical preparation in the form of a liquid dosage, preferably a soothing agent against cough, comprises a combination of at least two mucilaginous drugs, preferably a combination of iceland moss (Lichen islandicus) and at least a further mucilaginous drug, preferably together with a harmless, preferably pharmacologically-harmless carrier. An independent claim is included for a combination of at least two mucilaginous drugs, preferably combination of iceland moss (Lichen islandicus) and at least a further mucilaginous drug, preferably from marsh mallow (Althaea officinalis L.), ribwort (Plantago lanceolata L.), malves (Malva sylvestris L. and M. neglecta Wallr.), fenugreek (Trigonella foenum graecum L.), salep and quince (Cydonia oblonga Mill.), preferably in the form of their respective extracts, optionally together with at least a zinc compound, preferably for the use of the preventive and/or therapeutic treatment of and/or for production of a medicament for the preventive and/ ...

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10-11-2005 дата публикации

Solid dosage topical pharmaceutical composition, useful to treat inflammatory diseases of mouth and throat e.g. tonsillitis, laryngitis, pharyngitis, gingivitis and sore throat, comprises combination of viscous drug and a local anesthetic

Номер: DE202004016078U1
Автор:

Pharmaceutical composition (I), in solid dosage form, preferably for topical treatment of inflammatory diseases of mouth and throat, comprises a combination of at least a viscous drug (A) and/or its extract with at least a local anesthetic. ACTIVITY : Antiinflammatory; Analgesic; Antianginal. MECHANISM OF ACTION : None given.

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03-08-2021 дата публикации

Aronia-Ingwersaft

Номер: DE202020003318U1
Автор:

Aronia-Ingwersaft dadurch gekennzeichnet, dass der Aronia-Ingwersaft aus einem Gemisch von Aronia- und Ingwersaft besteht.

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27-04-2006 дата публикации

Active agent containing beverage, useful to treat e.g. asthma and sclerosis, comprises water, water mixed with carbonic acid, water Kefir crystals, sugars, fruits, flavorants, acidifying additives, ascorbic acid and natural colorants

Номер: DE102004051717A1
Принадлежит:

Active agent containing beverage (I) based on- and use- of water-Kefir-crystals comprises water (75 l), 25 l of water mixed with carbonic acid, water Kefir crystals (5 kg), sugars (5 kg), fruits (2-3 kg), flavorants, acidifying additives, ascorbic acid and natural coloring materials, related to 100 l. An independent claim is also included for the preparation of (I). ACTIVITY : Gastrointestinal-Gen.; Antiasthmatic; Antiinflammatory; Dermatological; Antianemic; Hepatotropic; Neuroprotective. MECHANISM OF ACTION : None given.

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01-04-1971 дата публикации

Номер: DE0002045836A1
Автор:
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03-02-1999 дата публикации

Process for producing a herbal composition

Номер: GB2327607A
Принадлежит:

One or more herbs are combined with a solvent, such as water or ethanol/water mixture. The mixture is heated and any ethanol is driven off. The resulting solution is preferably cooled and separated from any solid residue and is intended for use in the preparation of a medicinal herbal composition, preferably a homeopathic composition. Plant species which may be used are Taraxacum Officinale, Agrimonia Eupatoria, Berberis Vulgaris, Silybum Marianum, Tilia Europea, Crategus Oxyacanthoides, Zanthoxylum Americanum, Arcostaphylus Uva Ursi, Juniperus Communis, Petroselinum Crispum, Zea Mays, Echinacea Angustifolia, Belladonna, Arnica Montana, Thuja Occidentalis, Astragalus Membranaceous, Angelica Sinensis or Panax Ginseng.

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25-04-2001 дата публикации

VINEGAR FOR TREATING PARASITES

Номер: GB0002355404A
Принадлежит:

Aqueous solutions of apple cider vinegar display activity against parasite infestations in mammals. The solutions are for drinking (oral administration).

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25-06-2003 дата публикации

Skin treatments

Номер: GB0000311815D0
Автор:
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17-08-1994 дата публикации

Pharmaceutical compositions

Номер: GB0009412755D0
Автор:
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15-04-2020 дата публикации

Beet juice having increased intestinal absorption rate, preparation method therefor and use thereof

Номер: GB0002578035A
Автор: DAISIK HARM, Daisik Harm
Принадлежит:

The present invention relates to beet juice having an increased intestinal absorption rate, a preparation therefor and a use thereof and, more specifically, to: beet juice, which has an enhanced intestinal digestion and absorption rate through the conversion of high-molecular compounds into low-molecular compounds by means of low-temperature maturation of beets, has a grassy smell removed therefrom through the roasting of beets, and has a reduced grassy taste and bitterness by being mixed with carrot juice and apple juice; and an antioxidant or antihypertensive health food composition using the beet juice.

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23-01-2019 дата публикации

A sachet for making facial toner solution

Номер: GB0201820079D0
Автор:
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28-02-2015 дата публикации

Skin care

Номер: AP2015008280A0
Принадлежит:

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28-02-2015 дата публикации

Skin care

Номер: AP0201508280A0
Принадлежит:

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15-08-2010 дата публикации

COMPOSITIONS BASED ON PLANZENEXTRAKTEN FOR THE TREATMENT OF CANCER

Номер: AT0000474566T
Принадлежит:

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15-11-1990 дата публикации

PROCEDURE FOR THE PRODUCTION OF A PLANT EXTRACT

Номер: AT0000105482A
Автор:
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15-11-2007 дата публикации

EXCERPT FROM CHINESE HERBS

Номер: AT0000378057T
Принадлежит:

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15-08-2011 дата публикации

ORGANIC EXCERPT FROM THE GEUM JAPONICUM THUNB VAR. AND ITS USE

Номер: AT0000516808T
Принадлежит:

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15-03-1992 дата публикации

PSYLLIUM CONTAINING FUELLUNGSZUSAMMENSTELLUNGEN.

Номер: AT0000072944T
Принадлежит:

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15-08-2003 дата публикации

ANTITROMBOTI MEANS

Номер: AT0000245429T
Принадлежит:

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08-11-1994 дата публикации

Herbal extract composition

Номер: AU0006631094A
Принадлежит:

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16-01-2020 дата публикации

Preparing stable liquid emulsion forms of plant extract

Номер: AU2018283411A1
Принадлежит: Wallington-Dummer

A method (10) for preparing stable liquid emulsion forms of plant extract is provided. A plant extract is mixed (11) with a diluent oil as an oil mixture. Heat is applied (13) to the oil mixture until the mixture reaches a threshold viscosity. An emulsifying agent is dispersed (14) in water as an emulsifying solution. The oil mixture and emulsifying solution are mixed (16) together. The mixed oil mixture and emulsifying solution are homogenized (17) as a liquid form of the plant extract.

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15-06-2004 дата публикации

SOLUBLE ISOFLAVONE COMPOSITIONS

Номер: AU2003298659A1
Принадлежит:

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10-11-2011 дата публикации

Plant composition for the treatment or prevention of viral blood-borne diseases such as diseases caused by the human immunodeficiency virus (HIV) or hepatitis C

Номер: AU2009344046A1
Принадлежит:

The invention relates to a plant composition for the treatment or prevention of viral blood-borne diseases such as the diseases caused by the human immunodeficiency virus (HIV) or hepatitis C. According to the invention, the composition mainly includes flower of sulphur, a plant which contains catechins and a tannin agent, as well as a pharmaceutically acceptable medium. The invention also relates to the method for manufacturing said composition. The invention can be used in the field of treating or preventing viral blood-borne diseases such as the diseases caused by the human immunodeficiency virus (HIV) or hepatitis C.

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04-03-1999 дата публикации

Chinese herbs extract

Номер: AU0009811398A
Принадлежит:

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23-12-2002 дата публикации

Methods and compositions for helping the body resist the effects of the aging process

Номер: AU2002305833A1
Принадлежит:

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08-04-2004 дата публикации

ANTIALLERGIC AGENT AND ANTIINFLAMMATORY AGENT

Номер: AU2003262029A1
Принадлежит:

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07-03-2019 дата публикации

Extraction of polyphenolic compounds from pomace

Номер: AU2015252768B2
Принадлежит: Davies Collison Cave Pty Ltd

Methods of extraction of one or more polyphenolic compounds from pomace are described. The invention also provides uses of the extracts in the fortification of fruit juice, vegetable juice and foods, and as an antioxidant, an anti-inflammatory and an antifungal.

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24-10-2013 дата публикации

Methods for activating caspase-14 expression in human skin

Номер: AU2012225717A1
Принадлежит:

A method for treating human skin comprising the steps of a) identifying a subject deficient in caspase-14; wherein the caspase-14 deficiency is identified by the presence of a skin condition selected from the group consisting of eczema, xerotic skin, and skin dryness in at least one skin zone of the subject; and b) activating caspase-14 in human skin by administering to a subject in need thereof a therapeutically effective amount of a composition comprising one or more extracts selected from the group consisting of litchi, glasswort, peach, soja seed, sweet basil, cucumber, chanterelle, leek, kiwi fruit, rhubarb, grapefruit, wheat, raspberry, plum, and mixtures thereof.

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11-05-2017 дата публикации

Compositions and methods for prevention and treatment of brain diseases and conditions

Номер: AU2017202573A1
Принадлежит: Spruson & Ferguson

COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF BRAIN DISEASES AND CONDITIONS Disclosed herein are compounds, extracts, and active fractions of the plant Geumjaponicum and methods for preventing or treating brain diseases or conditions, such as ischemic stroke, Alzheimer's disease, vascular dementia, mild cognitive impairment (MCI), chronic cerebral ischemia and Parkinson's disease. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments.

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19-01-1996 дата публикации

Chinese herbs extract

Номер: AU0002747095A
Принадлежит:

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04-03-1999 дата публикации

Composition for the treatment of diarrhea, its use and its preparation

Номер: AU0000702672B2
Принадлежит:

Подробнее
15-04-1986 дата публикации

DRUG FOR THE TREATMENT OF THE NEOPLASTIC DISEASE

Номер: CA0001203167A1
Автор: DANILA, MIHAI
Принадлежит: ROBIC, ROBIC & ASSOCIES/ASSOCIATES

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04-11-1999 дата публикации

ANTITHROMBOTIC AGENTS

Номер: CA0002330013A1
Автор: DUTTA-ROY, ASIM
Принадлежит:

The invention provides a fruit extract or active fraction thereof for use in the prophylaxis or treatment of a disease state initiated or characterised by platelet aggregation.

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29-01-2004 дата публикации

FRUIT AND/OR VEGETABLE DERIVED COMPOSITION

Номер: CA0002492461A1
Принадлежит:

There is provided a process for making a composition suitable for topical application comprising the steps of: a)heating at least one fruit and/or vegetable pulp to up to a temperature in the range of about 40~C to 100~C; b) mixing between 1 and 40% w/w of a mild base with the heated fruit and/or vegetable pulp. There is also provided a fruit and/or vegetable derived composition suitable for topical application prepared by the above process. There is further provided a fruit and/or vegetable derived composition comprising at least one fruit and/or vegetable-derived pulp and a mild base, said composition having a pH in the range of about 7.5 to about 9.5.

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19-08-2014 дата публикации

BERRY OILS AND PRODUCTS

Номер: CA0002580628C
Принадлежит: GOWLING LAFLEUR HENDERSON LLP

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17-03-2011 дата публикации

COMPOSITION FOR IMPROVING LACTATION

Номер: CA0002773401A1
Принадлежит:

Disclosed is a novel composition effective to improve lactation and milk production in an animal. In some embodiments the composition comprises a fiber-depleted fraction derived from fenugreek in combination with additives that synergistically improve the effective of the composition. Additives that enhance the effect of the fenugreek fraction can include apple cider vinegar, fennel seed powder, saw palmetto berry extract, kelp powder, and methylsulfonylmethane.

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09-04-2009 дата публикации

GRANULE, TABLET AND METHODS FOR PRODUCING THE SAME

Номер: CA0002701605A1
Принадлежит:

Disclosed is a granule comprising: a carrier composed of a porous calcium silicate; a functional substance in an oily liquid form or a low-melting-point solid form and a water-soluble antioxidant, both of which are adsorbed on the carrier; and a granulation component. The object is to improve the storage stability of a powderized or tabletted functional substance (e.g., vitamin A) to a practically effective level.

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14-10-2010 дата публикации

PLANT COMPOSITION FOR THE TREATMENT OR PREVENTION OF VIRAL BLOOD-BORNE DISEASES SUCH AS DISEASES CAUSED BY THE HUMAN IMMUNODEFICIENCY VIRUS (HIV) OR HEPATITIS C

Номер: CA0002758365A1
Автор: EL KETTANY SLEIMEN
Принадлежит:

L'invention concerne une composition à base de plantes pour le traitement ou la prévention de maladies virales du sang telles que les maladies causées par le virus de l'immunodéficience humaine (VIH) ou l'hépatite C. Selon l'invention, la composition comprend principalement de la fleur de soufre, une plante contenant des catéchines et un agent tannin ainsi qu'un support pharmaceutiquement acceptable. L'invention concerne également le procédé de fabrication de cette composition. L'invention trouve application dans le domaine du traitement ou la prévention de maladies virales du sang telles que les maladies causées par le virus de l'immunodéficience humaine (VIH) ou l'hépatite C.

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14-05-1985 дата публикации

SKIN REGENERATING COSMETICAL COMPOSITION AND A PROCESS FOR THE PREPARATION THEREOF

Номер: CA1187000A
Принадлежит: INTERAG RT, INTERAG RESZVENYTARSASAG

Composition and process for the manufacture of epithelizing, skin regenerating, treating skin protecting preparations characterized by extracting one or more plants or parts of plants with ethanol under aerobic or anaerobic conditions. The novel composition or preparation provides a household remedy for excoriation which is harmless and the components of which are of natural origin and as such can be safely stored and used.

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06-12-1977 дата публикации

PROCESS FOR THE PREPARATION OF A PURIFIED EXTRACT OF QUILLAIA BARK

Номер: CA1022161A
Автор:
Принадлежит:

Подробнее
14-05-1985 дата публикации

SKIN REGENERATING COSMETICAL COMPOSITION AND A PROCESS FOR THE PREPARATION THEREOF

Номер: CA0001187000A1
Автор: SZELES LAJOS
Принадлежит:

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25-04-2019 дата публикации

INHIBITION OF ANDROGEN RECEPTOR BY EXTRACTS OF MEDICINAL HERBS AND COMPOSITIONS THEREOF

Номер: CA0003078437A1
Принадлежит: WILSON LUE LLP

In one embodiment, the present invention is directed to a composition comprising an aqueous or ethanolic extract of at least one herb selected from the group consisting of Aloe barbadensis (??:F3), Rheum palmatum L. (??:?6) Stephania tetrandra (???:C4), Phellodendron chinense Schneid. (??:D8), Euphorbia humifusa (???:S6), Eclipta prostrata (???:I2), A. venetum L. (???:FI), Portulaca oleracea L. (???:F5) and Sanguisorba officinalis L. (??:E5}, Camellia sinensis var.assamica (Mast) Kitamura (??:PE) and Punica granatum. (??:PG); and mixtures thereof. The composition is administered to a patient, in an effective amount, in a method of treating, inhibiting, preventing, reducing the incidence of, ameliorating or resolving a disease state or condition caused in part or exacerbated by hyperactivity of the androgen receptor (AR), by inhibiting the androgen receptor protein. These compositions may also be used inhibit or stabilize hair loss or grow hair in a subject in need.

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22-05-2020 дата публикации

APPLE PEEL POLYPHENOL EXTRACT FOR THE PREVENTION AND THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE

Номер: CA3119853A1
Принадлежит:

The present document describes apple peel polyphenolic extract comprising a proanthocyanidin content of at least 15000 µg/g of dry weight, comprising about 30% to about 35% epicatechin content, and pharmaceutical composition comprising the apple peel polyphenolic extract. The present document also describes methods and use of the apple peel polyphenolic extract for preventing or treating conditions such as oxidative stress, inflammation and mitochondrial dysfunction of the liver, insulin resistance, intestinal endothelial tissue injury, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis (NASH), liver fibrosis, liver cirrhosis, and/or inhibition of de novo lipogenesis and ß-oxidation of free fatty acids for preventing accumulation thereof in the liver. The present document also describes a process for extraction of at least a polyphenol content from dry apple peel powder.

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13-02-2020 дата публикации

CURCUMINOID COMPOSITIONS

Номер: CA3108111A1
Принадлежит:

The present invention relates to compositions comprising curcuminoids; in particular, compositions comprising curcuminoids that are highly water soluble. The present invention also relates to processes for providing such compositions and uses of such compositions.

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15-02-2007 дата публикации

METHOD FOR OBTAINING FRUIT WAX

Номер: CA0002617974A1
Принадлежит:

The invention relates to a method for obtaining fruit wax from plant constituents, said method being carried out essentially using compressed C2-C4 hydrocarbons. Unlike previous extraction methods with supercritical CO2, the inventive method can be carried out at low pressures and with a reduced extraction means throughput. Residues from the fruit treatment, especially peel from the juicing process, are used as starting materials. Preferred extraction agents are ethane, propane, butane and the mixtures thereof, the extraction itself being carried out in batches at pressures of < 50 mPa and temperatures of < 70 ~C, with an extraction agent throughput of between 4 and 20 kg/kg of starting materials. The extracted fruit wax is outstandingly suitable for cosmetic or pharmaceutical preparations, especially for the care and treatment of the skin.

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30-03-2004 дата публикации

COMPOSITION FOR SUPPRESSING CELLULAR FIBROUSING AND METHOD FOR PREPARING AN EXTRACT FROM LOQUAT SEEDS

Номер: CA0002339073C
Автор: NISHIOKA, YUTAKA
Принадлежит: KOCHI MEDICAL SCHOOL

The object of the present invention is to provide a useful composition capable of suppressing cellular fibrousing. The object is achieved by providing a composition containing an extract from loquat seeds. The composition of this invention is based on an extract from loquat seeds which is obtained by immersing grains obtained by pulverizing loquat seeds in at least one solvent selected from a group comprising ethanol, methanol, water and hexane, and separating a supernatant therefrom.

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14-02-2008 дата публикации

APPLES WITH HIGH POLYPHENOLIC CONTENT

Номер: CA0002660251A1
Принадлежит:

The invention relates to apples comprising high concentrations of polyphe nols, to processes for obtaining said apples and to uses of apples as a meth od of treatment or prophylaxis of cardiovascular disease, colon cancer and d igestive health.

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09-01-2018 дата публикации

FUNCTIONAL FOODS AND BEVERAGES WITH SYNERGISTIC PROPERTIES TO PROMOTE HOMEOSTASIS

Номер: CA0002837751C
Принадлежит: JUSTBIO INC., JUSTBIO INC

The present invention provides compositions having synergistic antioxidant properties in the modulation of Toll-like receptor signaling for the promotion of homeostasis, immunity, energy conservation, protection of neural cells and anti-inflammatory responses, said compositions comprising plant and/or fruit extracts and a natural sweetener with high oxidation potential as defined by ORAC value.

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09-08-2012 дата публикации

FUNCTIONAL FOODS AND BEVERAGES WITH SYNERGISTIC PROPERTIES TO PROMOTE HOMEOSTASIS

Номер: CA0002837751A1
Принадлежит:

The present invention provides compositions having synergistic antioxidant properties in the modulation of Toll-like receptor signaling for the promotion of homeostasis, immunity, energy conservation, protection of neural cells and anti-inflammatory responses, said compositions comprising plant and/or fruit extracts and a natural sweetener with high oxidation potential as defined by ORAC value.

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27-02-2014 дата публикации

SYSTEM AND PROCESS FOR EXTRACTION OF PRODUCTS FROM FRUITS AND VEGETABLES

Номер: CA0002882720A1
Принадлежит:

The present document describes a system and a process for the extraction of several products from apple peel. There are several unit operations involved including an ultrafiltration unit, concentration unit, and a three stage counter current separator centrifuge wherein water is used as the solvent. The final products that are extracted from apple peel include pectin, syrup, fibers, as well as soluble and dried retenate fractions.

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17-07-1992 дата публикации

COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CALCIUM OXALATE STONE DISEASE

Номер: CA0002100781A1
Принадлежит:

... 2100781 9212720 PCTABS00014 A compound for the treatment of calcium oxalate kidney stone disease which can be extracted and purified from leaves of the plant Eriobotrya japonica is disclosed. The compound has the following characteristics: inhibits calcium oxalate crystal growth in vitro, inhibits renal calcium oxalate crystal deposition in rats which are fed ethylene glycol, causes rats which are fed ethylene glycol and said compound to excrete less oxalate in their urine as compared to rats which are fed ethylene glycol without said compound, shows little or no loss in activity when exposed to an aqueous solution of pH 1.5 for 14 hours, shows increased activity when exposed to an aqueous solution of pH 12.7 for 15 hours, is polyanionic, is stable when heated in an aqueous solution (at pH of extract) at 98 ·C for 3 hours, water-soluble, insoluble in heptane, hexane, chloroform/methanol mix, diethyl ether, and ethanol/aqueous mix, binds to DEAE-A-25 Sephadex at pH 8.6 and is eluted from ...

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15-08-1996 дата публикации

PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF HERPES

Номер: CA0002211802A1
Принадлежит:

The invention relates to a pharmaceutical composition for the treatment of herpes simplex virus infections, comprising a quaternary ammonium compound as a first component and/or an antiviral agent as a second component and/or a plant extract as a third component, wherein the three components are mutually compatible, in a pharmaceutically acceptable base.

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02-06-2009 дата публикации

PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF HERPES

Номер: CA0002211802C

The invention relates to a pharmaceutical composition for the treatment of herpes simplex virus infections, comprising a quaternary ammonium compound as a first component and/or an antiviral agent as a second component and/or a plant extract as a third component, wherein the three components are mutually compatible, in a pharmaceutically acceptable base.

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15-12-2001 дата публикации

Topical antiinflammatory and antioxidant composition useful as cortisone substitute for treating dermatological disorders, comprising aqua hamamelidis, polyacrylamide, isoparaffins and laureth-7

Номер: CH0000691951A5
Автор: LUTZ BEAT CARL
Принадлежит:

A new pharmaceutical composition (I) contains (a) aqua hamamelidis (i.e. witch hazel extract), (b) polyacrylamide, (c) 13-14C isoparaffins and (d) laureth-7.

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26-01-2012 дата публикации

Formulations and treatments for trichology

Номер: US20120020982A1
Автор: Jon Phillips
Принадлежит: Individual

A formulation for trichological treatment of a patient including, in a dosage in the range of 3 g to 8 g: phytosterols in the range of 200 mg to 2500 mg; the quantitative equivalent of Polygonum multiflorum root 4:1 in 70% EW in the range of 600 mg to 2600 mg; methylsulfonylmethane in the range of 500 mg to 2000 mg; and bovine colostrum in the range of 500 m to 2000 m.

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03-05-2012 дата публикации

Composition for promoting adipocyte differentiation containing an extract of rehmannia glutinosa, licorice, coicis semen, hordei fructus, chaenomelis fructus, acanthopanacis cortex or puerariae radix

Номер: US20120107427A1
Принадлежит: Amorepacific Corp

Disclosed is a composition containing an active ingredient comprising one or more extracts selected from the group consisting of Rehmannia glutinosa , licorice, Coix lacryma - jobi seed, wheat germ, Chaenomeles sinensis fruit, Acanthopanacis cortex and Radix puerariae. The composition promotes adipocyte differentiation and fat globule production, and is effective in reducing skin wrinkles, increasing skin elasticity and preventing skin ageing.

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24-05-2012 дата публикации

Combination herbal product to benefit respiratory tract in people exposed to smoke

Номер: US20120128801A1
Принадлежит: Aadvantics Pharmaceuticals Inc

An herbal composition for providing a beneficial effect to the respiratory tract. The composition includes Thyme Leaf, Wild Cherry Bark, Cocoa Extract, Mullein Leaf Extract, and Boswellia Serrata . In particular, the composition may prevent or treat cough, specifically caused by exposure to smoke. Also described are methods of using the herbal composition.

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14-06-2012 дата публикации

Compositions and methods for the prevention and treatment of hypertension

Номер: US20120148691A1
Автор: Ming Li, Peng Peng
Принадлежит: Generex Pharmaceuticals Inc

Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum and methods for preventing or treating hypertension. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments.

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28-06-2012 дата публикации

Supplement comprising blackcurrants or boysenberries

Номер: US20120164252A1
Принадлежит: Gibb Holdings Nelson Ltd

The present invention relates to a dietary supplement comprising one or more of processed whole blackcurrants, processed whole boysenberries, one or more natural component extracted from blackcurrants, and one or more natural component extracted from boysenberries. The dietary supplement is particularly, but not exclusively, suitable for animals.

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02-08-2012 дата публикации

Cosmetic Preparation and Method for Preparing the Same

Номер: US20120195948A1
Принадлежит: MIBELLE AG

The present invention relates to the use of dedifferentiated plant cells in cosmetic preparations for protecting of stem cells against intrinsic and extrinsic stress factors, in particular for promoting proliferation of stem cells and for protecting them against apoptosis. In particular, the invention relates to the use of dedifferentiated plant cells from fruits of Malus domestica (Apple) cultivar Uttwiler Spaetlauber . Further, the invention relates to a method for cultivating of dedifferentiated plant cells, as well as to the preparation of extracts of plant cell cultures which are suitable for such applications.

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17-01-2013 дата публикации

Composition, and Method of Using the Composition, Effective for Minimizing the Harmful Effects Associated with Individuals Suffering from Alcohol Intoxication

Номер: US20130017276A1
Автор: Gregory Blackman

The present invention relates to a composition, and methods of using the composition, for minimizing the harmful effects associated with alcohol consumption. The composition includes a plurality of ingredients, which when combined, have the unexpected effect of increasing one or more metabolic pathways in the individual. As the metabolic rate is increased, alcohol is burned off, or utilized as energy source, and occurs at a considerably much faster rate than under normal physiological means. It is believed that the composition may have an effect on the brain causing it to increase metabolic rates. By administering the composition to an inebriated individual, the rate at which a person sobers up, occurs at a faster rate than would occur under normal physiological time frames.

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24-01-2013 дата публикации

Expression Modulator For Clock Gene Bmal

Номер: US20130022635A1
Принадлежит: Shiseido Co Ltd

The present invention provides a substance which can modulate expression of a Bmal gene effectively and with a wide range of application. Provided is an expression modulator for the Bmal gene comprising, as an active ingredient, one or more selected from the group consisting of hinoki cypress extract, chlorella extract, hop extract, Zanthoxylum extract, juniper oil, lavender oil, eucalyptus oil, olibanum, cypress oil, palmarosa oil, pineneedle oil, rose oil, ylang-ylang oil, elemi oil, petitgrain oil, pepper oil, thyme oil and chamomile oil.

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24-01-2013 дата публикации

Expression Modulator For Clock Gene Period

Номер: US20130022692A1
Принадлежит: Shiseido Co Ltd

The present invention provides a substance which can modulate expression of a Period gene effectively and with a wide range of application. Provided is an expression modulator for the Period gene comprising, as an active ingredient, one or more selected from the group consisting of arnica extract, nuphar extract, black tea extract, Zanthoxylum extract, juniper oil, cedar oil, lavender oil, clove bud oil, cypress oil, rose oil, ylang-ylang oil, galbanum oil, petitgrain oil, pepper oil, thyme oil, basil oil, and beta-caryophyllene.

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14-03-2013 дата публикации

Phenolic Compositions Derived From Apple Skin And Uses Thereof

Номер: US20130065843A1
Принадлежит: DALHOUSIE UNIVERSITY

Described herein are phenolic compositions derived from apple skins. In particular, described herein are flavonoid-rich fractions derived from apple skin extract. The compositions are useful in the prevention and treatment of conditions associated with oxidative stress and/or inflammation, including certain neurodegenerative diseases. Methods of producing the compositions are also described.

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21-03-2013 дата публикации

Oral Formulations For Promoting Cellular Purification

Номер: US20130071369A1
Принадлежит: NSE Products, Inc.

An oral formulation includes a plurality of agents that promote cellular detoxification. Agents can be included that modulate expression of Nrf2-associated genes upon ingestion of the oral formulation by a subject, wherein the Nrf2-associated genes include at least one gene encoding intrinsic antioxidants, and at least one gene encoding cellular detoxifiers. In addition, at least one of the plurality of agents attenuates inflammation. 1. An oral formulation comprising a plurality of agents that modulate expression of Nrf2-associated genes upon ingestion of the oral formulation by a subject , wherein the Nrf2-associated genes include at least one gene encoding intrinsic antioxidants , and at least one gene encoding cellular detoxifiers , and wherein at least one of the plurality of agents attenuates inflammation.2. The oral formulation of claim 1 , wherein the Nrf2-associated genes are selected from the group consisting of NFE2L2 claim 1 , GCLM claim 1 , GCLC claim 1 , GSR claim 1 , GSTA1 claim 1 , GPX1 claim 1 , GPX4 claim 1 , HMOX1 claim 1 , NQO1 claim 1 , SRXN1 claim 1 , SQSTM1 claim 1 , SOD1 claim 1 , UGT1A6 claim 1 , NOS2 claim 1 , NOS3 claim 1 , and PTGS2.3. The oral formulation of claim 2 , wherein at least one of the plurality of agents substantially reverses an age-related change in expression of at least one of the Nrf2-associated genes.4. The oral formulation of claim 1 , wherein the plurality of agents combine to modulate expression of at least five Nrf2-associated genes.5. The oral formulation of claim 1 , wherein at least one of the plurality of agents upregulates a gene encoding intrinsic antioxidants.6. The oral formulation of claim 1 , wherein at least one of the plurality of agents upregulates a gene encoding cellular detoxifiers.7. The oral formulation of claim 1 , wherein at least one of the plurality of agents stimulates autophagy in a tissue of the subject.8. The oral formulation of claim 1 , wherein the plurality of agents include at least two ...

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25-04-2013 дата публикации

FRUIT AND VEGETABLE-DERIVED COMPOSITIONS FIELD OF THE INVENTION

Номер: US20130101691A1
Принадлежит: Secret of Youth Ltd

This invention provides fruit and vegetable-derived compositions comprising a fruit or vegetable derivative of inter alia, at least one Beta, Capsicum and Malus species, wherein the composition is at a pH in the range of about 3 to about 6.5. The invention further provides for process for the production of the same and uses thereof. 1. A fruit and vegetable-derived composition comprising a fruit or vegetable derivative of at least one Beta , Capsicum and Malus species at a pH in the range of about 3 to about 6.5.2Citrus limonCitrus paradise. The fruit and vegetable-derived composition of claim 1 , further comprising a derivative of at least one of Solanum claim 1 , Cucumis claim 1 , a claim 1 , a claim 1 , and a Prunus.3. The fruit and vegetable-derived composition of claim 2 , further comprising a derivative of a Diospyros.4Citrus maxima.. The fruit and vegetable-derived composition of claim 2 , further comprising a derivative of a5Carica papaya.. The fruit and vegetable-derived composition of claim 2 , further comprising a derivative of a6. The fruit and vegetable-derived composition of wherein said fruit derivative comprises a pulp and a seed of said fruit and optionally a zest claim 1 , a peel or a combination thereof.7. The fruit and vegetable-derived composition of wherein said vegetable derivative comprises a pulp of said vegetable and a peel of said vegetable.8. A method for the treatment or prophylaxis of a dermatologic disease or disorder in a mammal claim 1 , comprising topically applying an effective amount of the fruit and vegetable-derived composition of to the mammal.9. The method according to claim 8 , wherein said dermatologic disease or disorder is psoriasis claim 8 , acne claim 8 , seborrhea claim 8 , eczema claim 8 , skin erosion claim 8 , skin inflammation claim 8 , hair loss claim 8 , diabetic ulcers or lesions claim 8 , wrinkles claim 8 , or skin fissures.10. The method according to claim 8 , wherein said dermatologic disease or disorder is ...

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16-05-2013 дата публикации

Compositions of rose hips enriched with seeds of rose hips and their use as anti-inflammatory natural medicine for alleviating/reducing symptoms associated with inflammation and joint diseases such as arthritis, rheumatoid arthritis and/or osteo-arthritis

Номер: US20130122126A1
Принадлежит: HYBEN VITAL LICENS APS

A composition containing rose hip flesh or rose hips including the naturally occurring amount of seeds, or a concentrate is enriched with rose hip seeds for reducing and/or alleviating symptoms of inflammatory diseases. A method of preparing the rose hip seeds involves separating the rose hip seeds from the flesh prior to or after drying. Drying is preferably performed below 50° C. with the rose hip seeds then ground into a powder and mixed with a rose hip composition, a concentrate or an extract containing rose hip shells or Rose hips including their naturally occurring amount of seeds providing a product enriched with Rose hips seeds preferably containing at least 50% up to 85%, (by weight) of rose hip seeds. The composition is useful in the prophylaxis, treatment or alleviation of symptoms related to inflammatory diseases, in particular joint diseases, such as arthritis rheumatoid arthritis and/or osteo arthritis.

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13-06-2013 дата публикации

Herbal composition for preventing and/or treating anxiety related conditions

Номер: US20130149370A1
Автор: Nadav Kately, Ravid Doron
Принадлежит: OPMOP Ltd

The present invention relates to herbal compositions for the treatment and/or prevention of anxiety disorders or stress. These compositions comprise hawthorn fruit (Shan Zha), light wheat grain (Fu xiao mai) and Lilly Bulb (bai hi) in amounts which are effective to treat anxiety conditions. The compositions may further comprise Chinese date (Da zao).

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20-06-2013 дата публикации

PHYTONUTRIENT COMPOSITIONS AND METHODS TO PROTECT AGAINST RADICAL MEDIATED CELLULAR AND DNA DAMAGE

Номер: US20130156870A1
Принадлежит: Metaproteomics, LLC

Phytonutrient based compositions and methods of using the same for preventing, reducing, or treating genetic damage induced by environmental toxins are disclosed. 1Acacia nilotica. A phytonutrient composition for preventing , reducing , or treating genetic damage induced by environmental agents , wherein said composition comprises therapeutically effective amounts of two or more compounds selected from the group consisting of extract , artichoke extract , blueberry extract , catechins , chlorogenic acid , cinnamon , ellagic acid , grape seed extract , hesperidin , Momodica extract , prune extract , rosemary extract , and watercress extract and said composition is in a dosage form suitable for oral administration.2. The composition according to claim 1 , wherein said composition provides per dosage form:{'i': 'Acacia nilotica', 'a. from 0.5 mg to 10 mg of extract;'}b. from 0.5 mg to 10 mg of artichoke extract;c. from 1 mg to 25 mg of blueberry extract;d. from 2.5 mg to 25 mg of catechins;e. from 25 mg to 75 mg of chlorogenic acid;f. from 0.5 mg to 10 mg of cinnamon;g. from 10 mg to 100 mg of ellagic acid;h. from 2.5 mg to 50 mg of grape seed extract;i. from 15 mg to 120 mg of hesperidin;j. from 0.5 mg to 10 mg of Momodica extract;k. from 0.5 mg to 10 mg of prune extract;l. from 0.5 mg to 10 mg of rosemary extract; andm. from 0.5 mg to 10 mg of watercress extract.3Acacia nilotica. A method for preventing claim 1 , reducing claim 1 , or treating genetic damage induced by environmental agents claim 1 , wherein said method comprises administering a composition comprising therapeutically effective amounts of two or more compounds selected from the group consisting of extract claim 1 , artichoke extract claim 1 , blueberry extract claim 1 , catechins claim 1 , chlorogenic acid claim 1 , cinnamon claim 1 , ellagic acid claim 1 , grape seed extract claim 1 , hesperidin claim 1 , Momodica extract claim 1 , prune extract claim 1 , rosemary extract claim 1 , and watercress ...

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27-06-2013 дата публикации

COMPOSITION CONTAINING PRUNUS MUME EXTRACT FOR EXTERNAL APPLICATION TO SKIN

Номер: US20130164391A1
Принадлежит:

The present disclosure provides a composition for external application to the skin for skin care after laser treatment, which contains extract as an active ingredient. The composition for external application to the skin according to the present disclosure has skin-soothing, skin barrier-recovering and pain-relieving effects and, therefore, can be developed into a cosmetic composition having additional effects of protecting sensitive skin, preventing skin sensitivity, providing skin stability and moisturizing the skin. 1Prunus mume. A method for aftercaring a skin after laser treatment to the skin in a subject , comprising transdermally administering an effective amount of extract to the subject.2Prunus mume. The method according to claim 1 , wherein the extract soothing soothes the skin claim 1 , relieves skin pain or recovers the skin barrier.3Prunus mumePrunus mume. The method according to claim 1 , wherein the extract is administered in a form of a composition comprising 0.001-10 wt % of the extract based on the total weight of the composition.4. (canceled)5Prunus mume. The method according to claim 1 , wherein the extract protects sensitive skin claim 1 , prevents skin sensitivity claim 1 , provides skin stability and moisturizes the skin after laser treatment.6. The method according to claim 3 , wherein the composition is in the form selected from a group consisting of solution claim 3 , suspension claim 3 , emulsion claim 3 , paste claim 3 , gel claim 3 , lotion claim 3 , cream claim 3 , essence claim 3 , pack claim 3 , soothing mask claim 3 , topical patch claim 3 , makeup base claim 3 , moisturizing oil claim 3 , powder claim 3 , soap claim 3 , surfactant-containing cleanser claim 3 , oil claim 3 , powder foundation claim 3 , emulsion foundation claim 3 , wax foundation claim 3 , oil-in-water (O/W) or water-in-oil (W/O) emulsion and spray. The present disclosure relates to a composition containing Prunus mume extract for external application to the skin. ...

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27-06-2013 дата публикации

COMPOSITION FOR IMPROVING SEXUAL WELLNESS

Номер: US20130164394A1
Принадлежит: HORPHAG RESEARCH (IP) PRE LTD.

The invention relates to improving sexual fitness or wellness of both sexes, the male sexual enhancement, the treatment of sexual dysfunction and the health of the sexual vascular system of both sexes with ingredients that consist in a source of proanthocyanidins, a source of arginine, rose hip extracts and/or extracts. The source of proanthocyanidins may be a botanical extract and the source of arginine may be from arginine aspartate. 1. A preparation consisting in a combination of:a source of proanthocyanidins,a source of arginine,{'i': 'Quercus robur', 'Rose hip and/or extracts thereof or and/or extracts thereof or a mixture thereof, and a suitable excipient.'}2. The preparation according to claim 1 , wherein said source of arginine is arginine or citrulline or ornithine or any arginine precursors or derivatives thereof.3. The preparation of or claim 1 , wherein said source of arginine is a salt or dipeptide of L-arginine and aspartic acid.4. The preparation of to claim 1 , wherein said source of proanthocyanidins is originated from a plant extract or from a synthesized material.5. The preparation of claim 4 , wherein the plant extract is selected from the group consisting of proanthocyanidins containing extracts selected among extracts of pine bark claim 4 , grape seed claim 4 , apples claim 4 , peanut skin claim 4 , walnuts claim 4 , pomegranates claim 4 , raspberry claim 4 , currants (black) claim 4 , blueberry claim 4 , almonds claim 4 , tea claim 4 , hawthorn claim 4 , cocoa or combination thereof.6. The preparation of claim 5 , wherein the plant extract is originated from pine bark claim 5 , preferably the French maritime pine bark.7. The preparation of any of to claim 5 , wherein Rose hip and/or extracts thereof comprise carotenoids claim 5 , tocopherols claim 5 , tocotrienols claim 5 , vitamin C claim 5 , polyphenols and glycosides of mono- or di- or triacylglycerol compounds.8. The preparation of any of to claim 5 , wherein the suitable excipient is a ...

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27-06-2013 дата публикации

Apple Skin Extracts for Treating Cardiovascular Disease

Номер: US20130165396A1

Pharmaceutical and nutraceutical compositions and methods for treating cardiovascular disease, comprising apple skin extracts which can reduce cholesterol levels and inhibit low density lipoprotein (LDL) oxidation in a subject, are provided.

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04-07-2013 дата публикации

Composition Comprising Cudrania Tricuspidata and Coix Lachryma-Jobi for Suppressing Obesity or Lowering Blood Sugar, and Use Thereof

Номер: US20130171276A1
Принадлежит: KOREA FOOD RESEARCH INSTITUTE

The present invention relates to a pharmaceutical composition for suppressing obesity or lowering blood sugar which comprises extract and -extract, and more specifically relates to a pharmaceutical composition for suppressing obesity or lowering blood sugar which comprises extract and extract, to a functional health food or food additive composition for suppressing obesity or lowering blood sugar which comprises extract and -extract, to a tablet having an obesity-suppressing function and blood-sugar lowering effect which is produced using and - 17-. (canceled)8. A method for preparing a tablet for suppressing obesity or lowering blood sugar , comprising the steps of:{'i': Cudrania tricuspidata', 'Coix lachryma', 'jobi', 'Dioscorea Rhizome', 'Morus alba', 'Hovenia dulcis, Glycyrrhiza uralensis', 'Rubus coreanus Miguel', 'Cnidium', 'Lycium', 'Schizandra', 'Astragalus', 'Cudrania tricuspidata', 'Coix lachryma', 'jobi, '(a) mixing extract and -extract with 10-50 parts by weight of one or more herbal medicines selected from the group consisting of red ginseng, ginseng, , the leaf of , the fruit, stem, and leaf of , cinnamon bark, Golden thread, , Dodder seed, fruit, fruit, fruit and root, based on 100 parts by weight of extract and -extract so as to prepare a mixture;'}{'i': Cudrania tricuspidata', 'Coix lachryma', 'jobi', 'Cudrania tricuspidata, Coix lachryma', 'jobi, herbal medicines, and functional substances;, '(b) adding to the mixture one or more functional ingredients selected from the group consisting of 1-5 parts by weight of vitamin, 1-10 parts by weight of saccharide, 0.5-5 parts by weight of squalene, 0.5-5 parts by weight of taurine, 1-10 parts by weight of herb, 0.1-5 parts by weight of octacosanol and 1-5 parts by weight of sodium alginate, based on 100 parts by weight of extract and -extract, and mixing them so as to prepare a mixture of -'}(c) ripening the mixture at 5-20° C. for 10-20 hours;(d) preparing tablets using a tabletting machine; and(e) ...

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04-07-2013 дата публикации

Cosmetic compositoin containing a rubus coreanus extract for diminishing skin wrinkles

Номер: US20130171282A1
Принадлежит: Amorepacific Corp

The present invention relates to a cosmetic composition containing a Rubus coreanus extract as an active ingredient, and more particularly to a cosmetic composition containing an extract from Rubus coreanus processed by traditional oriental medicinal processing technology, in which the Rubus coreanus extract has an excellent effect of reducing skin wrinkles by inhibiting the formation of SNARE complexes and the release of a neurotransmitter. The cosmetic composition has excellent stability in formulations compared to conventional products for reducing skin wrinkles and exhibit effects similar to Botox which has been used to reduce skin wrinkles, thereby greatly reducing skin wrinkles without causing adverse effects.

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18-07-2013 дата публикации

Pharmaceutical Composition for Topical Application

Номер: US20130184242A1
Автор: Dov Tamarkin, Meir Eini
Принадлежит: Foamix Ltd

A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.

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12-09-2013 дата публикации

SYSTEMS AND METHODS FOR TREATING FIBROMYALGIA

Номер: US20130236572A1
Автор: Kingsley Joe D.
Принадлежит:

A solution and method for treating symptoms commonly associated with fibromyalgia. The solution includes a solvent and a composition including active ingredients of menthol, camphor, and capsaicin, as well as additional components including aloe vera extract, carbomer, decyl polyglucose, deionized water, grapefruit seed extract, green tea extract, orange peel extract, queen of the prairie extract, rose water, silica, sodium, hydroxymethyl glycinate, vegetable glycerin, witch hazel, and yucca extract. The method includes soaking an affected area in the solution for a predetermined period of time. 1. A method of administering a composition for relieving symptoms associated with fibromyalgia of a patient having such symptoms , the method comprising:(i) providing a composition including menthol at about 0.5% v/v to about 10% v/v, camphor at about 0.5% v/v to about 10% v/v, capsaicin at about 0.005% v/v to about 0.1% v/v, and therapeutic amounts of aloe vera extract, carbomer, decyl polyglucose, a grapefruit seed extract, an orange peel extract, a green tea extract, a queen of the prairie extract, rose water, a hydroxymethyl glycinate, a glycerin, witch hazel, and yucca extract;(ii) diluting the composition in a solvent to provide a solution having a desired volume percent of the composition; and(iii) soaking an affected area of the patient in the solution for a desired period of time.2. The method of claim 1 , further comprising repeating step (iii).3. The method of claim 2 , wherein step (iii) is repeated up to three times within a twenty-four hour period.4. The method of claim 2 , wherein step (iii) is repeated at an hourly interval.5. The method of claim 2 , wherein step (iii) is repeated as needed to relieve the symptoms.6. The method of claim 1 , wherein the amount of menthol is about 3% v/v of the composition.7. The method of claim 1 , wherein the amount of camphor is about 3% v/v of the composition.8. The method of claim 1 , wherein the amount of capsaicin is ...

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12-09-2013 дата публикации

PROCESS FOR PYGEUM EXTRACTION

Номер: US20130236574A1
Автор: Sharma Ashok, Tewari Kiran
Принадлежит:

An improved process for the extraction of from the plant of the family rosacaea, amygdales tribe, genus species () and related species (as herein defined) comprising the steps of collecting the plant material i.e. stem cuttings/twigs, removing the leaves and drying till moisture content is about 10-15%, powdering the stem material, extracting with chlorinated organic solvents and water-alcohol mixture, in ratio of 1:4, filtering and drying the extract under vacuum at 30 degree Celsius to obtain a greenish mass with bitter almond smell, the mass being referred to as ‘’ wherein in the improved process, a ‘renewable plant source’ i.e. stem cuttings/twigs, are used for extraction of instead of a ‘non-renewable’ source such as bark of the tree. The obtained by the new process has a pharmacopeia profile similar to the product ‘’ obtained from a ‘non-renewable source’ i.e. bark of . Further, it is non-toxic and shows anti-BPH (benign prostatic hyperplasia) activity comparable with that of obtained from non-renewable source i.e. bark of 19-. (canceled)10pygeumPrunus domesticaIndian prunus. A commercially viable process using biowaste for the extraction of from () comprising the steps of:{'i': 'Prunus domestica;', 'collecting ‘bio-waste’ in the form of stem cuttings/twigs with leaves removed, obtained during routine ‘pruning’ or trimming process of'}drying the bio-waste till moisture content is about 10-15%;powdering the same by pulverization;extracting the powdered stem material with chlorinated organic solvents or water-alcohol mixture, in ratio of 1:4 at 35-40° C.; and{'i': 'pygeum', 'filtering and drying the extract under vacuum at 30° C. to obtain ‘’ as a greenish mass with bitter almond smell and in which concentration of total sterols typically calculated as beta-sitosterol, is 15-18% and same has anti-BPH activity.'}11. The process of wherein the chlorinated organic solvents used in the extraction process are methylene dichloride (MDC) or chloroform.12. The process ...

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19-09-2013 дата публикации

Use of a Traditional Chinese Medicine Composition for Manufacturing a Health Food or Medicament for Preventing and Alleviating Physical Fatigue

Номер: US20130243748A1
Принадлежит: JIANGZHONG PHARMACEUTICAL CO., LTD.

The present invention provides a use of traditional Chinese medicine composition for manufacturing a health food or medicament for preventing and alleviating physical fatigue. The composition consists of 5-90 parts by weight of Radix Panacis Quinquefolii, 5-160 parts by weight of 1-90 parts by weight of fermented powder and/or 1-120 parts by weight of , and these ingredients are made from Chinese crude drugs or from Chinese crude drug extracts in amounts equivalent to those of the Chinese crude drugs. The composition may further contain 5-90 parts by weight of Flos Rosae Rugosae. The present invention also relates to the use of said composition in the manufacture of prophylactic or therapeutic health foods or medicaments for reducing blood lipids, for resisting oxidation, and for enhancing anoxia endurance. The medicine composition of the present invention can be prepared into any conventional dosage forms by adding any pharmaceutically acceptable auxiliary agents. 1GanodermaCordyceps sinensis. A method of resisting oxidation or enhancing anoxia endurance comprising the step of administering a composition to a subject , wherein the composition comprises raw materials of 10-50 parts by weight of Radix Panacis Quinquefolii , 10-50 parts by weight of , and 10-50 parts by weight of fermented powder , or water extracts of said raw materials , as active ingredients.2. The method of claim 1 , characterized in that said raw materials further include 10-40 parts by weight of Flos Rosae Rugosae claim 1 , or a water extract of 10-40 parts by weight of Flos Rosae Rugosae.3GanodermaCordyceps sinensis. The method of claim 1 , characterized in that the raw materials are 30 parts of Radix Panacis Quinquefolii claim 1 , 40 parts of claim 1 , and 20 parts of fermented powder.4. The method of claim 3 , characterized in that said raw materials further include 30 parts by weight of Flos Rosae Rugosae claim 3 , or a water extract of 30 parts by weight of Flos Rosae Rugosae. ...

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19-09-2013 дата публикации

BIOLOGICALLY ACTIVE FOOD ADDITIVE FOR PREVENTING CARDIOVASCULAR DISEASES AND REINFORCING THE CARDIOVASCULAR SYSTEM

Номер: US20130243881A1
Автор: Elistratov Dmitriy G.
Принадлежит:

The biologically active food additive comprises hawthorn flowers and/or berries and/or leaves and royal jelly in the following ingredient ratio: from 10 mass % to 90 mass % of hawthorn; from 10 to 24 mass % of royal jelly; and from 0 mass % to 70 mass % of fillers. The additive is produced in powder, tablet or capsule form, or aqueous-alcoholic extract form. The complex system of biologically active substances contained in the proposed biologically active food additive not only exerts an effect on the entire cardiovascular system, but also reduces the causes of cardiovascular diseases and improves quality of life in old age by acting on the pathology of the human body. This long-acting agent for prophylaxis and planned health improvement has no contraindications or side effects even during long-term use (more than one year). 1. A biologically active food additive for preventing cardiovascular diseases and enhancing the cardiovascular system comprises hawthorn flowers and/or berries and/or leaves , royal jelly and excipient in a following ratio of the ingredients:hawthorn flowers and/or berries and/or leaves: from 61 to 90 wt. %,royal jelly: from 10 to 24 wt. %,excipients: from 0 to 29 wt. %.2. The biologically active food additive as claimed in claim 1 , wherein the additive is made in a powder form.3. The biologically active food additive as claimed in claim 1 , wherein the additive is made in a capsulated form.4. The biologically active food additive as claimed in claim 1 , wherein the additive is made in a tableted form.5. The biologically active food additive as claimed in claim 1 , wherein the additive is made in an aqueous alcoholic extract form. This application is a U.S. National phase application of the International application WO 2011/078736 A1 (PCT/RU2010/000704) and claims priority to application 2009144334 filed on Nov. 30, 2009 in the Russian Federation, both applications being hereby incorporated by reference in their entirety.1. Field of the ...

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03-10-2013 дата публикации

TIE2 Activator, Vascular Endothelial Growth Factor (VEGF) Inhibitor, Angiogenesis Inhibitor, Vascular Maturing Agent, Vascular Normalizing Agent and Vascular Stabilizing Agent, and Pharmaceutical Composition

Номер: US20130259952A1
Автор: KISO Akinori, OHTO Nobuaki
Принадлежит:

A Tie2 activator containing, as an active ingredient, a hawthorn extract, a starfruit extract, a shellflower extract, a lotus extract, a rooibos extract, an Indian date extract, a Chinese quince extract, a Psidium guava extract, a long pepper extract, a Quillaja extract, a Kouki extract, a ginkgo extract, an oyster extract, a turmeric extract, a chrysanthemum extract, a jujube extract, a Chinese wolfberry extract, a chamomile extract, or a Butcher's Broom extract, or any combination thereof. 1. A Tie2 activator comprising , as an active ingredient , a hawthorn extract , a starfruit extract , a shellflower extract , a lotus extract , a rooibos extract , an Indian date extract , a Chinese quince extract , a Psidium guava extract , a long pepper extract , a Quillaja extract , a Kouki extract , a ginkgo extract , an oyster extract , a turmeric extract , a chrysanthemum extract , a jujube extract , a Chinese wolfberry extract , a chamomile extract , or a Butcher's Broom extract , or any combination thereof.2. An angiogenesis inhibitor comprising , as an active ingredient , a hawthorn extract , a starfruit extract , a shellflower extract , a lotus extract , a rooibos extract , an Indian date extract , a Chinese quince extract , a Psidium guava extract , a long pepper extract , a Quillaja extract , a Kouki extract , a ginkgo extract , an oyster extract , a turmeric extract , a chrysanthemum extract , a jujube extract , a Chinese wolfberry extract , a chamomile extract , or a Butcher's Broom extract , or any combination thereof.3. A vascular maturing agent comprising , as an active ingredient , a hawthorn extract , a starfruit extract , a shellflower extract , a lotus extract , a rooibos extract , an Indian date extract , a Chinese quince extract , a Psidium guava extract , a long pepper extract , a Quillaja extract , a Kouki extract , a ginkgo extract , an oyster extract , a turmeric extract , a chrysanthemum extract , a jujube extract , a Chinese wolfberry extract , a ...

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31-10-2013 дата публикации

NOVEL USES FOR TRADITIONAL CHINESE MEDICINE

Номер: US20130287870A1
Принадлежит:

The present invention relates to the use of one or more Neuroaid2 components to activate Kchannels and in the treatment of various diseases and disorders. The one or more Neuroaid2 components are selected from the group consisting of: Salviae Miltiorrhizae, Prunus persica; Polygalae; acori tatarinowii; Astragali; Paeoniae Rubra; Chuanxiong; Carthamus tinctorius; and angelicae sinensis. 3. A method according to claim 1 , wherein the one or more Neuroaid2 components is all nine Neuroaid2 components claim 1 , preferably in the form of a single composition and/or in about the same ratios as employed in the MLC901 composition.4. A composition or kit according to claim 2 , wherein the one or more Neuroaid2 components is all nine Neuroaid2 components claim 2 , preferably in the form of a single composition and/or in about the same ratios as employed in the MLC901 composition.5. A method according to claim 1 , wherein the treating or the disease or disorder is selected from the group consisting of:prevention of ischemic or reperfusion injury; treatment of hyperinsulemia or hyperinsulinism; treatment of hypoglycemia; prevention of the transition from prediabetes to diabetes; treatment of type II diabetes; correction of the defects in insulin secretion and insulin sensitivity contributing to prediabetes and type II diabetes; preservation of pancreatic function in type I diabetics; treatment of hyperlipidemia; prevention of weight gain in individuals who are predisposed to obesity; treatment of obesity; treatment of metabolic syndrome (or syndrome X); treatment of polycystic ovary syndrome; treat weight gain, dyslipidemia, or impairment of glucose tolerance in subjects treated with antipsychotics drugs; prevent weight gain, dyslipidemia, or impairment of glucose tolerance in subjects treated with antipsychotics drugs; and treatment of any disease where hyperlipidemia, hyperinsulemia, hyperinsulinism, hyperlipidemia, hyperphagia or obesity are contributing factors to the ...

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31-10-2013 дата публикации

REFRESHING BEVERAGE

Номер: US20130287871A1
Автор: Coy Johannes
Принадлежит:

The invention relates to a novel sweet-tasting refreshing beverage, which is free of phosphoric acid and instead contains at least 0.3% by weight/volume of gluconic acid, which is low in minerals, specifically contains less than 250 mg/liter of minerals, which is low in sugar, specifically contains at most 2.5% by weight/volume of sugar, wherein these sugars comprise at least 10% weight/weight galactose and in addition a proportion of isomaltulose and/or tagatose, and which has a glycemic index of at most 35 (GI<35). 1. A sweet-tasting refreshing beverage that is low in minerals and is low in sugar comprising:a content of gluconic acid that is at least 0.3 wt/vol %,any content of minerals that is less than 250 mg/liter,a content of sugars that comprises a fraction of galactose that is at least 10 weight-weight % based on the content of sugars, said content of sugars additionally comprising a content of isomaltulose and/or tagatose and/or trehalose and/or ribose, wherein the content of sugars in the beverage is at most 2.5 wt/vol %,and wherein the beverage has a glycemic index of at most 35 (GI<35) and is free from phosphoric acid.2. The beverage as claimed in claim 1 , wherein the content of minerals is less than 150 mg per liter.3. The beverage as claimed in claim 1 , wherein the beverage has a content of fruit juices or fruit juice extracts.4Stevia.. The beverage as claimed in claim 1 , wherein the beverage additionally has a content of5. The beverage as claimed in claim 1 , wherein the beverage comprises a content of caramel coloring and natural flavorings and has a cola-like taste.6. The beverage as claimed in claim 5 , wherein the flavorings are Mentha arvensis and/or coca leaf and/or galangal and/or ginger and/or cardamom and/or kola nut and/or cocoa and/or lime and/or mace and/or clove and/or orange and/or pine and/or mustard seed and/or licorice and/or vanilla and/or lemon and/or cinnamon or extracts thereof.7. The beverage as claimed in claim 1 , wherein ...

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07-11-2013 дата публикации

Pharmaceutical composition for strengthening spleen and stomach and preparation method therefor

Номер: US20130295079A1

A pharmaceutical composition for strengthening spleen and stomach and a preparation method therefor. The method includes the step of mixing four substances listed below to obtain a mixture, wherein the mixture is the pharmaceutical composition for strengthening spleen and stomach, and the four substances are (A) ginseng ethanol extract, (B) volatile oil of largehead atractylodes rhizome and tangerine peels, (C) aqueous extract of Indian bread, yamaimo, lotus seeds, tangerine peels, liquorice root, hawthorn fruit, germinated barley, largehead atractylodes rhizome and rhizoma alismatis; (D) fermentation broth of fruits and vegetables. 19.-. (canceled)10. A method for preparing a pharmaceutical composition for strengthening spleen and stomach , comprising: mixing following four substances to obtain a mixture , i.e. , the pharmaceutical composition for strengthening spleen and stomach; wherein the four substances are (A) ginseng ethanol extract , (B) volatile oil of largehead atractylodes rhizome and tangerine peel , (C) aqueous extract of Indian bread , yamaimo , lotus seed , tangerine peel , liquorice root , hawthorn fruit , germinated barley , largehead atractylodes rhizome and rhizoma alismatis , and (D) fermentation broth of fruits and vegetables ,the substance (A) is prepared by a method comprising a step of extracting an extract from ginseng with ethanol water by a reflux extraction to obtain the ginseng ethanol extract,the substance (B) is prepared by a method comprising steps of soaking largehead atractylodes rhizome and tangerine peel in water, distilling the largehead atractylodes rhizome and the tangerine peel to obtain distillate and dregs, and collecting the distillate to obtain the volatile oil of largehead atractylodes rhizome and tangerine peel,the substance (C) is prepared by a method comprising steps of mixing Indian bread, yamaimo, lotus seed, liquorice root, hawthorn fruit, germinated barley, rhizoma alismatis, the dregs obtained in preparation of ...

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07-11-2013 дата публикации

Pharmaceutical composition for treating melasma and preparation method thereof

Номер: US20130295080A1

A pharmaceutical composition for treating melasma is provided. The pharmaceutical composition is prepared from ginseng, salvia, mint, orange peel, peony, poria, licorice, peach seed, yam, and a fermentation conversion solution of fruits and vegetables. A preparation method of the pharmaceutical composition is also provided. 19-. (canceled)10. A method for preparing a pharmaceutical composition for treating melasma , comprising:mixing the following four substances for obtaining a mixture, wherein the mixture is the pharmaceutical composition for treating the melasma, wherein the four substances comprises:{'i': 'penthorum chienese', 'A) ethanol extract of ginseng and salvia; B) volatile oil of mint and orange peel; C) aqueous extract of the ginseng, the salvia, the mint, the orange peel, peony, poria, licorice, peach seed, yam and ; D) a fermentation conversion solution of fruits and vegetables;'}wherein a method for preparing the A) substance comprises: mixing the ginseng and the salvia, processing reflux extraction on the mixture with an aqueous solution of ethanol for obtaining extract and a first residue, collecting the extract, wherein the extract is the ethanol extract of the ginseng;wherein a method for preparing the B) substance comprises: immersing the mint and the orange peel in water, processing distillation extraction for obtaining distillate and a second residue, wherein the distillate is the volatile oil of the mint and the orange peel;{'i': penthorum chienese', 'penthorum chienese;, 'wherein a method for preparing the C) substance comprises: mixing the peony, the poria, the licorice, the peach seed, the yam, the , the first residue and the second residue, boiling, filtering and collecting filtrate, adding absolute ethanol and waiting for collecting supernatant, wherein the supernatant is the aqueous extract of the ginseng, the salvia, the mint, the orange peel, the peony, the poria, the licorice, the peach seed, the yam and the'}{'i': Lactobacillus ...

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21-11-2013 дата публикации

PROCESS FOR PRODUCING AQUEOUS SOLUTION CONTAINING FAT-SOLUBLE SUBSTANCE

Номер: US20130309218A1
Принадлежит: Wacker Chemie AG

The purpose of the present invention is to provide a process for producing an aqueous solution containing a fat-soluble substance. A combination of a super dissolution aid, cyclodextrin and a fat-soluble substance or a combination of the super dissolution aid and a cyclodextrin complex of the fat-soluble substance is used for dissolving the fat-soluble substance, whereby it becomes possible to provide an aqueous solution containing the fat-soluble substance at a high concentration and an aqueous solution having improved transdermal absorbability of the fat-soluble substance contained therein. 1. A method for producing an aqueous solution containing at least one fat-soluble substance selected from the group consisting of: polyphenols , flavonoids , tocopherols , retinols , menaquinones , carotenoids , propolis or cinnamic acid derivatives , diterpenes , terpenes , coenzyme Q10 and α-lipoic acid , said method comprising adding to water a solubilizer and at least one of (a) cyclodextrin and the at least on fat-soluble substance , wherein the solubilizer is a member selected from the group consisting of:1) an alkali salt or bile acid selected from the group consisting of taurocholate, glycocholate, cholic acid, lithocholic acid and deoxycholic acid,2) glycosides of polyphenols or hesperidin,3) an emulsifier selected from the group consisting of glycerin fatty acid ester, sorbitan fatty acid ester, propylene glycol fatty acid ester, and, sucrose fatty acid ester,4) a lecithin agent selected from the group consisting of enzymatically decomposed lecithin, lecithin derived from soybean and, lecithin derived from egg yolk,5) a saponin selected from the group consisting of glycyrrhizic acid or an alkali salt thereof, soybean saponin and quillaja saponin,6) a casein or alkali salt thereof,7) a polysorbate (fatty acid polyoxyethylene sorbitan),8) a cellulose or alkali salt thereof selected from the group consisting of methylcellulose, carboxymethyl cellulose and hydroxyethyl ...

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21-11-2013 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DEMENTIA CONTAINING PRUNUS MUME EXTRACT

Номер: US20130309334A1
Принадлежит: KOREA INSTITUTE OF ORIENTAL MEDICINE

The present invention relates to a composition for preventing or treating dementia containing an extract of (Fructus Mume), and the extract of the present invention has outstanding effects in improving spatial recognition ability and in normalizing hippocampal damage (normalizing ERK phosphorylation, increasing ChAT and normalizing NF-kappa B) induced by chronic vascular brain damage in a vascular dementia animal model, and hence can be used to advantage as a medicinal product for preventing or treating dementia diseases and as a functional health food for preventing or alleviating dementia diseases that accompany vascular brain damage such as vascular dementia. 1. A method for the treatment of dementia containing the step of administering a pharmaceutically effective dose of Fructus Mume extract to a subject having dementia.2. The method for the treatment of dementia according to claim 1 , wherein the extract is extracted by using water claim 1 , alcohol claim 1 , or the mixture thereof as a solvent.3. The method for the treatment of dementia according to claim 2 , wherein the alcohol is C-Clower alcohol.4. The method for the treatment of dementia according to claim 3 , wherein the lower alcohol is ethanol or methanol.5. The method for the treatment of dementia according to claim 1 , wherein the extract is extracted by ultrasonification/heat combined extraction.6. The method for the treatment of dementia according to claim 1 , wherein the dementia is vascular dementia or Alzheimer's disease.713-. (canceled) 1. Field of the InventionThe present invention relates to a composition for preventing or treating dementia containing Fructus Mume extract.2. Description of the Related ArtDementia is diagnosed when memory disorder is so severe as to bring difficulty in daily life including work, social life, and personal relationship with accompanying at least one of the following 4 symptoms; speech disorder, disorientation, decline of calculation ability, and character & ...

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05-12-2013 дата публикации

PLANT EXTRACTS FOR THE TREATMENT AND PREVENTION OF INFECTIONS

Номер: US20130323335A1
Принадлежит:

A composition comprising a plant extract and at least one additional plant extract selected from the group consisting of an plant extract, a plant extract, a plant extract, a plant extract and a plant extract is disclosed. Compositions comprising plant extract or Ailanthone are also disclosed. 180-. (canceled)81Sanguisorbae officinalisAilanthus altissima. A method of treating and/or preventing infection in a subject in need thereof , the method comprising administering to the subject a therapeutically effective amount of a composition comprising a plant extract and an plant extract , thereby treating and/or preventing infection in the subject.82. The method of claim 81 , wherein said infection is secondary to chronic inflammation.83. The method of claim 81 , wherein said infection is secondary to atopic dermatitis.84Sanguisorbae officinalisAilanthus altissima. A method of treating and/or preventing atopic dermatitis in a subject in need thereof claim 81 , the method comprising administering to the subject a therapeutically effective amount of a composition comprising a plant extract and an plant extract claim 81 , thereby treating and/or preventing infection in the subject.85. The method of claim 81 , wherein said infection is associated with a disease selected from the group consisting of an atopic disease claim 81 , a contact dermatitis claim 81 , a nummular dermatitis claim 81 , a radiation dermatitis claim 81 , a burn claim 81 , a non-atopic eczema claim 81 , a pressure sore claim 81 , an eye inflammatory disease claim 81 , a respiratory inflammatory diseases claim 81 , an asthma claim 81 , a gastrointestinal disease and an oral infectious disease.86. The method of claim 81 , wherein said therapeutically effective amount is for downregulating secretion of a Th2 type cytokine selected from the group consisting of IL-4 claim 81 , IL-5 claim 81 , IL-6 claim 81 , IL-10 and IL-13 in a cell of said subject.87. The method of claim 81 , wherein said therapeutically ...

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19-12-2013 дата публикации

PLANT EXTRACTS FOR TREATING BURNS AND CHRONIC WOUNDS

Номер: US20130337090A1
Автор: Doron Shirli
Принадлежит: SKIN MATRIX LTD.

The present invention provides compositions and methods for treating burns and chronic wounds, particularly compositions comprising an oil extract or oily suspension of a combination of plant material derived from several plant species for treating burns and chronic sores. 1Harpagophytum procumbensAngelica archangelica. A composition comprising as an active ingredient an oil extract or oily suspension of a combination of ground roots of (Devil's claw) and (Angelica).2Hydrastis canadensis. The composition of claim 1 , wherein the active ingredient further comprises an oil extract or oily suspension of ground roots of (Golden Seal).3Astragalus membranaceousSymphytum officinaleUrtica dioica. The composition of claim 1 , further comprising an oil extract or oily suspension of at least one of ground root of (Astragalus); ground leaves of (Comfrey) ground leaves of (Stinging Nettle) or any combination thereof.4Agrimonia Eupatoria. The Composition of claim 3 , further comprising an oil extract or oily suspension of ground leaves of (Agrimony) and ground blue-green algae.5Harpagophytum procumbensAngelica ArchangelicaAstragalus membranaceousSymphytum officinaleUrtica dioicaAgrimonia Eupatoria. The composition of comprising as an active ingredient an oil extract or oily suspension of a combination of ground plant material comprising roots of (Devil's claw) claim 4 , (Angelica) and (Astragalus); leaves of (Comfrey) claim 4 , (Stinging Nettle) and (Agrimony); and blue-green algae.6Hydrastis Canadensis. The composition of claim 5 , wherein the active ingredient further comprises an oil extract or oily suspension of ground roots of (Golden Seal).7Harpagophytum procumbensAngelica ArchangelicaAstragalus membranaceousSymphytum officinaleUrtica dioicaAgrimonia Eupatoria. The composition of claim 5 , consisting of an oil extract or oily suspension of a combination of ground plant material consisting of roots of (Devil's claw) claim 5 , (Angelica) and (Astragalus); leaves of (Comfrey) ...

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19-12-2013 дата публикации

PHYTONUTRIENT COMPOSITIONS AND METHODS OF USE

Номер: US20130337092A1
Принадлежит: Metaproteomics, LLC

Phytonutrient based compositions and methods of using the same for preventing, reducing, or treating genetic damage induced by environmental toxins are disclosed. Additionally, said compositions and methods are used to reduce oxidized low density lipoproteins (OxLDL), myeloperoxidase (MPO), and plasminogen activator inhibitor-1 (PAI-1). 1Acacia niloticaMomodica. Use of a composition for simultaneously reducing serum OxLDL , MPO , and PAI-1 levels in a subject in need thereof , wherein said use comprises administering a composition comprising therapeutically effective amounts of two or more compounds or extracts selected from the group consisting of extract , artichoke extract , blueberry extract , catechins , chlorogenic acid , cinnamon , ellagic acid , grape seed extract , hesperidin , extract , prune extract , rosemary extract , and watercress extract and said composition is in a dosage form suitable for oral administration wherein said dosage form provides:{'i': 'Acacia nilotica', 'a. from 0.5 mg to 10 mg of extract;'}b. from 0.5 mg to 10 mg of artichoke extract;c. from 1 mg to 25 mg of blueberry extract;d. from 2.5 mg to 25 mg of catechins;e. from 25 mg to 75 mg of chlorogenic acid;f. from 0.5 mg to 10 mg of cinnamon;g. from 10 mg to 100 mg of ellagic acid;h. from 2.5 mg to 50 mg of grape seed extract;i. from 15 mg to 120 mg of hesperidin;{'i': 'Momodica', 'j. from 0.5 mg to 10 mg of extract;'}k. from 0.5 mg to 10 mg of prune extract;l. from 0.5 mg to 10 mg of rosemary extract; andm. from 0.5 mg to 10 mg of watercress extract.2Acacia niloticaMomodica. The use according to claim 1 , wherein the composition provides three or more compounds or extracts selected from the group consisting of extract claim 1 , artichoke extract claim 1 , blueberry extract claim 1 , catechins claim 1 , chlorogenic acid claim 1 , cinnamon claim 1 , ellagic acid claim 1 , grape seed extract claim 1 , hesperidin claim 1 , extract claim 1 , prune extract claim 1 , rosemary extract claim 1 ...

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26-12-2013 дата публикации

Anti-fatigue composition

Номер: US20130344179A1
Автор: Michel Grise
Принадлежит: Individual

The present invention relates to a food supplement composition for reducing fatigue, and/or improving recovery and resistance to fatigue. The composition comprised of collagen hydrolysate, blueberry extract and liquorice extract.

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09-01-2014 дата публикации

Bleomycin hydrolase production promotor

Номер: US20140010901A1
Принадлежит: Shiseido Co Ltd

Provided is a novel bleomycin hydrolase production promoter. Provided is a bleomycin hydrolase production promoter, natural moisturizing factor production promoter, and dry skin remedy, comprising as an active ingredient thereof one or a plurality of ingredients selected from the group consisting of chestnut rose extract, angelica root extract, cork tree bark extract, lamium album extract, rosemary extract, benzenesulfonyl GABA and erythritol.

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16-01-2014 дата публикации

COMPOSITION AND METHOD FOR TREATING FAT TISSUES AND INFLAMMATORY PROCESSES

Номер: US20140017341A1
Автор: Gourlaouen Brigitte
Принадлежит:

The process of the invention relates to a kit of two cosmetic, pharmaceutical, veterinary and food compositions, designed for slimming or for preventing and/or repairing inflammatory mechanisms, one of the compositions comprising at least one sirtuin activator and at least one HSP activator, and the other composition comprising at least one sirtuin inhibitor and at least one HSP inhibitor. 121-. (canceled)22. A cosmetic , pharmaceutical , food or veterinary combination comprising a first composition containing at least one sirtuin inhibitor and at least one HSP inhibitor , and a second composition containing at least one sirtuin activator and at least one HSP activator.23. The combination of claim 22 , wherein the first composition contains no sirtuin activator and no HSP activator claim 22 , and the second composition contains no sirtuin inhibitor and no HSP inhibitor.24. The combination of claim 22 , wherein the two compositions are packaged separately.25. The combination of claim 22 , wherein the combination has an increased efficacy in treatment or prevention of an inflammatory process in a patient compared to treatment with either the first or the second composition alone.26. The combination of claim 22 , wherein the combination has an increased efficacy in treatment or prevention of inflammatory processes in a patient compared to treatment with both i) a composition containing sirtuin inhibitors and no HSP inhibitor claim 22 , and ii) a composition containing sirtuin activators and no HSP activator.27. The combination of claim 22 , wherein the first composition and/or the second composition comprises at least one vascular activating agent.28. The combination of claim 27 , wherein the vascular activating agent is selected from the group consisting of AHAs (Alpha-hydroxy acids) claim 27 , and isoflavons or a plant extract containing same claim 27 , such as an extract of cassava or an extract of clover claim 27 , an extract of St. John's wort claim 27 , an ...

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13-02-2014 дата публикации

ANTACID FORMULATIONS AND ASSOCIATED METHODS

Номер: US20140044809A1
Автор: Brainard Elliott F.
Принадлежит:

The present invention provides antacid compositions and associated methods. In one aspect for example, an antacid composition suitable for delivery to a subject for reducing a digestive condition includes an effective amount of at least one citrate compound, an effective amount of blueberry product, and an effective amount of fruit extract including a member selected from the group consisting of pomegranate extract, bilberry extract, elderberry extract, blueberry extract, and combinations thereof. 1. An antacid composition suitable for delivery to a subject for reducing a digestive condition , comprising:an effective amount of at least one citrate compound;an effective amount of a blueberry product selected from the group consisting of blueberry fiber, blueberry fruit, and combinations thereof; andan effective amount of fruit extract including a member selected from the group consisting of pomegranate extract, bilberry extract, elderberry extract, blueberry extract, and combinations thereof.2. The composition of claim 1 , wherein the citrate compound is selected from the group consisting of magnesium citrate claim 1 , calcium citrate claim 1 , sodium citrate claim 1 , potassium citrate claim 1 , and combinations thereof.3. The composition of claim 1 , wherein the citrate compound includes magnesium citrate and calcium citrate.4. The composition of claim 1 , wherein the fruit extract includes at least two members selected from the group consisting of pomegranate extract claim 1 , bilberry extract claim 1 , elderberry extract claim 1 , blueberry extract claim 1 , and combinations thereof.5. The composition of claim 1 , wherein the fruit extract includes pomegranate extract claim 1 , bilberry extract claim 1 , and elderberry extract.6. The composition of claim 5 , wherein the fruit extract includes blueberry extract.7. The composition of claim 1 , wherein the blueberry product is blueberry fiber and the composition is formulated as a member selected from the group ...

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13-02-2014 дата публикации

Method and process for relieving or preventing symptoms

Номер: US20140044811A1
Принадлежит:

A method for relieving or preventing symptoms associated with uric acid crystals, comprising consuming a formulation that supports three or more processes, the processes comprising: 1. A method for relieving or preventing symptoms associated with uric acid crystals , comprising consuming a formulation that supports three or more processes that reduce a symptom due to uric acid crystals in a body , the processes comprising:1) a process that inhibits formation of uric acid in the body;2) a process that increases elimination of uric acid from the body; and3) a process that interferes with formation of uric acid crystals in the body.2. The method of claim 1 , wherein the formulation comprises an extract of celery claim 1 , an extract of cherry claim 1 , and a lithium salt.3. The method of claim 2 , wherein the extract of celery is from a seed.4. The method of claim 2 , wherein the extract of cherry is from a fruit.5. The method of claim 2 , wherein the lithium salt is selected from the group consisting of lithium orotate claim 2 , lithium aspartate claim 2 , lithium proteinate claim 2 , lithium citrate claim 2 , lithium carbonate claim 2 , and mixtures thereof.6. The method of claim 5 , wherein the lithium salt is selected from the group consisting of lithium orotate claim 5 , lithium aspartate claim 5 , lithium proteinate claim 5 , and mixtures thereof.7. The method of claim 2 , wherein the formulation comprises from 25 to 200 mg of extract of celery claim 2 , from 100 to 1500 mg extract of cherry claim 2 , and from 1.5 to 10 mg of elemental lithium in the lithium salt; and wherein the formulation is consumed from one to four times per day.8. The method of claim 2 , wherein the formulation comprises from 1.5 to 10 mg of elemental lithium in the lithium salt.9. The method of claim 1 , wherein the formulation is consumed from once every other day to once per day.10. The method of claim 1 , wherein the extract of celery is standardized to contain at least 50% 3-n- ...

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20-02-2014 дата публикации

COLD INFUSION PROCESS FOR FORTIFYING CORN AND/OR SOYBEANS

Номер: US20140050804A1
Автор: Sweeney Michael B.
Принадлежит: Voyava Republic LLC

This invention relates to a cold infusion process for fortifying corn and/or soybeans with one or more vitamin, non-vitamin, mineral, non-mineral, botanical, hormone, herb, neutraceutical, lipid, carbohydrate, amino acid, acid, salt, prebiotic, or probiotic functional additives. This invention also discloses an infused corn and/or soybean produced by the process of infusing the corn and/or soybean at a temperature of less than about 120° F. with a solution comprising water, a bridge initiator for acid salt bias, fortifying agent(s), and an acid in a quantity sufficient to reach a pH of about 3.65. Further, this invention provides a method for the infusion of a corn and/or soybean with at least one fortifying agent at approximately room temperature. 1. A method for the infusion of a corn with at least one fortifying agent comprising the steps of:a.) roasting the corn;b.) allowing the corn to cool to approximately room temperature;c.) preparing a fortifying solution comprising at least one fortifying agent, a bridge initiator for acid salt bias, an acid, and water, wherein the solution has a pH of between about 4 to about 3.5; andd.) mixing the roasted corn with the fortifying solution.2. The method of claim 1 , wherein the at least one fortifying agent is a vitamin claim 1 , non-vitamin claim 1 , mineral claim 1 , non-mineral claim 1 , botanical claim 1 , hormone claim 1 , herb claim 1 , neutraceutical claim 1 , lipid claim 1 , carbohydrate claim 1 , amino acid claim 1 , acid claim 1 , salt claim 1 , prebiotic claim 1 , or probiotic.3. The method of claim 1 , wherein the solution further comprises about 3500-4000 g of water claim 1 , about 80-110 g of betaine claim 1 , about 150-1500 g of at least one fortifying agent claim 1 , and citric acid in a quantity sufficient to reach a pH of about 3.65 per gallon of solution.4. The method of claim 1 , wherein the fortifying solution comprises a plurality of fortifying agents.5. The method of claim 1 , wherein the fortifying ...

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27-02-2014 дата публикации

Pharmaceutical Compositions for the Treatment of Warts

Номер: US20140057006A1
Принадлежит: ATP Marketing & Promotion AG

The present invention relates to pharmaceutical compositions for the treatment, and especially topical treatment, of warts and the use thereof for the treatment of warts. Specifically, the present invention relates to pharmaceutical compositions for the treatment of warts, comprising: a) 0.1 to 10 weight % dimethicone; b) 5 to 25 weight % of one or more vegetable oils; c) one or more pharmaceutically acceptable excipients and/or carriers; d) 2 to 6 weight % urea; and e) water up to 100 weight %. 1. A method of treating warts , comprising: a) 0.1 to 10 weight % dimethicone;', 'b) 5 to 25 weight % of one or more vegetable oils;', 'c) one or more pharmaceutically acceptable excipients and/or carriers;', 'd) 2 to 6 weight % urea; and', 'e) water up to 100 weight %., 'applying a topical medicament to at least one wart, the medicament comprising2. The method according to claim 1 , wherein said one or more vegetable oils of said medicament are chosen from the group consisting of almond oil claim 1 , tea tree oil claim 1 , lavender oil claim 1 , geranium oil claim 1 , lemon oil claim 1 , thuja oil claim 1 , and cinnamon oil.3. The method according to claim 1 , the medicament further comprising:f) 0.5 to 2 weight % red pepper powder.4. The method according to claim 1 , wherein said one or more pharmaceutically acceptable excipients and/or carriers of said medicament are chosen from the group consisting of ammonium acryloyldimethyl taurate/VP copolymer claim 1 , sodium benzoate claim 1 , potassium sorbate and citric acid.5. The method according to claim 1 , wherein the medicament comprises:a) 0.5 to 3 weight % dimethicone; 1) 1 to 3 weight % almond oil;', '2) 1 to 3 weight % tea tree oil;', '3) 1 to 2 weight % lavender oil;', '4) 1 to 2 weight % geranium oil;', '5) 0.5 to 2 weight % lemon oil;', '6) 0.5 to 2 weight % thuja oil; and', '7) 0.5 to 2 weight % cinnamon oil;, 'b) vegetable oils comprising 1) 0.5 to 3 weight % ammonium acryloyldimethyl taurate/ VP copolymer;', '2) 0 ...

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06-03-2014 дата публикации

Methods for Radiation Protection

Номер: US20140065247A1
Автор: DJANG ARTHUR H.K.
Принадлежит: Sante International, Inc.

Provided is a method for protecting an individual against radiation-induced internal damage that comprises administering an effective amount of an oral composition. The oral composition comprises a mixture of (hawthorn), and (green tea) to an individual so that radiation-induced internal damage will be prevented or ameliorated. 1Gynostemma pentaphyllum, Crataegus pinnatifidaCamellia sinensis. A method for protecting an individual against radiation-induced internal damage comprising administering an effective amount of an oral composition comprising a mixture of (hawthorn) , and (green tea) to an individual so that radiation-induced internal damage is prevented or ameliorated.2Gynostemma pentaphyllum,Camellia sinensisCrataegus pinnatifida. The method according to wherein the composition comprises about 10 to about 30 percent by weight of about 10 to about 30 percent by weight of (green tea) claim 1 , and about 40 to about 75 percent by weight of (hawthorn).3Gynostemma pentaphyllum,Camellia sinensisCrataegus pinnatifida. The method according to wherein the composition comprises about 10 to about 30 percent by weight of a mixture of an aqueous extract and an alcohol extract of about 10 to about 30 percent by weight of a mixture of an aqueous extract and an alcohol extract of (green tea) claim 1 , and about 40 to about 75 per-cent by weight of a mixture of an aqueous extract and an alcohol extract of (hawthorn).4. The method according to wherein the radiation is ionizing radiation selected from the group consisting of alpha radiation claim 1 , beta radiation claim 1 , gamma radiation claim 1 , neutron radiation claim 1 , X-ray and a combination thereof.5. The method according to wherein the effective amount is a prophylactically effective amount administered before exposure to radiation.6. The method according to wherein the effective amount is a therapeutically effective amount administered at one or more times of during radiation exposure claim 1 , and after radiation ...

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13-03-2014 дата публикации

Andrographis Paniculata Compositions and Methods for Treatment of Addictions

Номер: US20140072662A1
Автор: Ciccocioppo Roberto
Принадлежит:

Methods and compositions for the treatment or prevention of addictions and impulse control disorders using , active substances contained therein and extracts thereof, alone or in combination with other therapeutic agents. The methods and compositions of the invention are useful in the treatment or prevention of addiction to substances, including alcohol, nicotine, marijuana, opioid agonists cocaine, and amphetamines, as well as impulse control disorders, including pathological gambling and pathological overeating. 1Andrographis paniculataAndrographis paniculata. A method of treating substance addiction or an impulse control disorder or reducing the likelihood of relapse use of an addictive substance or practice of a behavior associated with an impulse control disorder , comprising administering to a subject in need thereof a composition comprising an effective amount of or an active substance or extract of , wherein the composition is effective to treat the substance addiction or impulse control disorder or reduce the likelihood of relapse use of the addictive substance or practice of the behavior associated with the impulse control disorder.2Andrographis paniculata. The method of claim 1 , wherein the composition comprises an extract of in a solvent.3. The method of claim 1 , wherein the composition comprises dehydroandrographolide claim 1 , andrographolide or neoandrographolide.4. The method of claim 3 , wherein the composition comprises andrographolide.5. The method of claim 1 , where in the composition further comprises at least one polyunsaturated fatty acid that upregulates PPARγ.6. The method of claim 5 , wherein the composition comprises a polyunsaturated fatty acid selected from eicosapentaenoic acid claim 5 , conjugated linoleic acid and docosahexaenoic acid.7Cornus kousa, Cistus Salvifolius, Glycyrrhiza glabraAlbizia julibrissin, ArisaemaCnidium monnieri, Pinellia ternataTribulus terrestris. The method of claim 1 , wherein the composition further ...

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27-03-2014 дата публикации

BIOLOGICALLY ACTIVE DIETARY SUPPLEMENT FOR NORMALIZING THE ANDROGEN LEVEL IN MEN AND THE OVERALL CONDITION AND REDUCING OBESITY

Номер: US20140086999A1
Принадлежит:

Biologically active dietary supplements (BADS) are proposed for normalizing the hormone balance and the overall condition in men based on natural ingredients. The BADS contain white cinquefoil roots and rhizomes or the above-ground part of white cinquefoil, or a mixture thereof, as well as drone brood in a quantity of from 20 mass % to 80 mass %. The disclosure makes it possible to produce a product which demonstrates, by virtue of an optimally selected ratio of ingredients, a synergistic effect in relation to the normalization of the androgen level and the prophylaxis of obesity in men. 1 aerial portions of white cinquefoil, or', 'mixture thereof; and, '(a)—roots and rhizomes of white cinquefoil, or'}(b) drone brood in the weight proportion of: from 20 wt % to 80 wt %.. A biologically active dietary supplement for normalizing the androgen levels in men, improving general health and reducing obesity, said dietary supplement comprises: This application is a U.S. national stage application of an international application PCT/RU2011/000294 filed on 3 May 2011, published as WO2012150872, which international application claims priority of a Russian Federation patent application RU2010117666 filed on 3 May 2011.The invention relates to food industry, namely, to biologically active dietary supplements (BADS) used for normalization of hormonal profile and general health in men and produced based on natural ingredients.A prior art search on this matter showed the existence of large number of known herbal-based agents and promoting the normalization of hormonal profile and metabolic processes.There is known a broad-spectrum treatment and prevention remedy containing propolis and milk thistle oil (Patent of Russian Federation No. 2175238, A 61 K 35/78). Due to the claimed combination of its ingredients, this biologically active supplement is effective in terms of its ergogenic action, stimulation of mental and physical activity and natural resistance of the body, and ...

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02-01-2020 дата публикации

Scorpion repel surface treatments and method for same

Номер: US20200000082A1
Принадлежит: Individual

A system and method of applying a slick surface, such as silicone epoxy, is applied on a vertical wall (on or around the perimeter of a structure), as a means of preventing (bark) scorpions (or other insects/arachnids) from climbing up walls. The system is intended, in part, to keep the Arizona bark scorpions out of homes. Vertical surface areas around the home are treated with a material such as silicone. A clear silicone epoxy, that when dry, prevents scorpions from climbing vertically up into a home or structure. This non-toxic epoxy is applied to the base of a home, including door thresholds, steps or other parts of a home which makes contact with the ground. The epoxy is applied to the area by sprayer.

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06-01-2022 дата публикации

APPLE PEEL POLYPHENOL EXTRACT FOR THE PREVENTION AND THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE

Номер: US20220000959A1
Автор: LEAHY Michael, LEVY Emile
Принадлежит:

The present document describes apple peel polyphenolic extract comprising a proanthocyanidin content of at least 15000 μg/g of dry weight, comprising about 30% to about 35% epicatechin content, and pharmaceutical composition comprising the apple peel polyphenolic extract. The present document also describes methods and use of the apple peel polyphenolic extract for preventing or treating conditions such as oxidative stress, inflammation and mitochondrial dysfunction of the liver, insulin resistance, intestinal endothelial tissue injury, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis (NASH), liver fibrosis, liver cirrhosis, and/or inhibition of de novo lipogenesis and β-oxidation of free fatty acids for preventing accumulation thereof in the liver. The present document also describes a process for extraction of at least a polyphenol content from dry apple peel powder. 1. An apple peel polyphenolic extract comprisinga proanthocyanidin (PAC) content of at least 15000 μg/g of dry weight, comprising epicatechin momomers and oligomers having from about 1 to 5 epicatechin units, from about 3500 to 4000 μg/g of dry weight;', 'epicatechin oligomers having from about 6 to 10 epicatechin units, from about 1000 to 1100 μg/g of dry weight; and', 'epicatechin polymers having >10 epicatechin units, from about 500 to 600 μg/g of dry weight., 'an about 30% to about 35% epicatechin content comprising'}2. The apple peel polyphenolic extract of claim 1 , wherein said epicatechin momomers and oligomers having from about 1 to 5 epicatechin units comprises epicatechin monomers claim 1 , from about 700 to 800 μg/g of dry weight.3. The apple peel polyphenolic extract of claim 1 , wherein said epicatechin momomers and oligomers having from about 1 to 5 epicatechin units comprises epicatechin dimers claim 1 , from about 1000 to about 1200 μg/g of dry weight.4. The apple peel polyphenolic extract of claim 1 , wherein said epicatechin momomers and oligomers having from about 1 ...

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04-01-2018 дата публикации

PREPARATION FOR PROTECTING AGAINST EXTRINSIC AND INTRINSIC SKIN AGING

Номер: US20180000722A1
Принадлежит:

Disclosed is a cosmetic or dermatological preparation which comprises one or more extracts of (purple saxifrage) and/or one or more extracts of (alpine snowbell). The use of these extracts to combat extrinsic and intrinsic skin aging is likewise described. 1Soldanella alpina. A cosmetic or dermatological preparation , wherein the preparation is suitable for topical application to human skin and for cosmetic and/or dermatological use , is present as at least one of a dispersion , gel , aqueous and/or alcoholic solution , serum , oil , tincture , ointment , salve or wipe impregnation media and comprises , based on a total weight of the preparation , from 0.0001% to 15% by weight of (i) one or more extracts of , as well as one or more components selected from fats , oils , waxes , moisturizing and/or humectant substances , alcohols , polyols , polymers , electrolytes , organic solvents , silicones , foam stabilizers , substances for preventing foaming , dyes , coloring pigments , thickeners.2Saxifraga oppositifolia.. The preparation of claim 1 , wherein the preparation further comprises from 0.0001% to 15% by weight of (ii) one or more extracts of3. The preparation of claim 2 , wherein the preparation comprises from 0.0001% to 1% by weight of (i) and/or from 0.0001% to 1% by weight (ii).4. The preparation of claim 1 , wherein (i) comprises at least one water-soluble extract obtained by hydro-alcoholic extraction of plant material.5. The preparation of claim 4 , wherein the plant material comprises plant leaves and/or plant stems.6. The preparation of claim 1 , wherein (i) comprises at least one oil-soluble extract obtained by supercritical fluid extraction of plant material.7. The preparation of claim 6 , wherein the plant material comprises plant leaves and/or plant stems.8. The preparation of claim 1 , in which all of the one or more extracts (i) are water-soluble or all of the one or more extracts (i) are oil-soluble.9Chlamydocapsa. The preparation of claim 1 , ...

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05-01-2017 дата публикации

COMPOSITIONS AND METHODS COMPRISING SIRTUINS

Номер: US20170000703A1
Принадлежит:

The present technology relates to cosmetic and pharmaceutical compositions useful for controlling the rate of cell destruction and minimizing the appearance of aging. In particular, the present technology relates to compositions and methods related to a combination of a sirtuin activator with a sirtuin-offsetting agent. 1. A composition comprising:(a) a sirtuin stimulator; and(b) a sirtuin-offsetting agent.2. The composition of claim 1 , wherein the amounts of (a) and (b) are selected to optimize the cell maintenance in a patient.3. The composition of claim 1 , wherein (b) comprises a non-sirtuin histone deacetylase inhibitor (HDACi).4. A cosmetic composition comprising:(c) a first composition that comprises a sirtuin stimulator; and(d) a second composition that comprises a sirtuin-offsetting agent.5. The composition of in the form of a gel claim 4 , cream claim 4 , spray claim 4 , suspension claim 4 , liquid claim 4 , paste or lotion.6. A method of formulating a composition claim 4 , the method comprising:(a) selecting a sirtuin or sirtuin stimulator having a known quantitative prolonging effect on a cell's life; and(b) selecting a sirtuin-offsetting agent having a known quantitative opposite effect on the cell's life; and(c) optimizing the balance between the two effects based on a known desired ultimate effect on the cell.7. A method of prolonging the life of a cell and simultaneously avoiding proliferation of cell damage claim 4 , the method comprising the steps of:(a) stimulating Sirt1 activity in the cell; and(b) inhibiting a non-sirtuin HDAC in the cell. The present application is a continuation-in-part application of U.S. application Ser. No. 14/518,860, filed on Oct. 20, 2014, entitled “COMPOSITIONS AND METHODS COMPRISING SIRTUIN STIMULATORS AND NON-SIRTUIN PROTEIN DEACETYLASE INHIBITORS”, which is incorporated herein by reference in its entirety.The present technology relates to cosmetic and pharmaceutical compositions useful for controlling the rate of ...

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07-01-2016 дата публикации

Gargle Method to Reduce the Duration of Common Cold Symptoms

Номер: US20160000826A1
Автор: Brown Amy C
Принадлежит:

A method of reducing the presence, duration, severity, or symptoms of the common cold entails the administration of a nonalcoholic antiviral remedy to a subject in need of such treatment, preferably in the form of a gargle. 1. A method of treating a patient to reduce the duration or symptoms of the common cold , comprising administering by a gargling method an aliquot of an herbal containing at least one agent selected from the group consisting of antivirals , astringents , acids , antibiotics , minerals , salts , and antimicrobials to a patient in need of such treatment.2. A method of treating a patient to reduce the duration or symptoms of the common cold , comprising administering by the oral route of administration an effective amount of a substance selected from the group consisting of hydrogen peroxide , baking soda , garlic , cayenne pepper , zinc , vinegar , citric acid , malic acid , oxalic acid , benzoic acid , quinic acid , tannic acid , ginger extract , olive whole leaf , fennel , eucalyptus or ascorbic acid effective to treat said patient.3. The method of claim 2 , wherein the nonalcoholic claim 2 , antiviral remedy comprises hydrogen peroxide.4. The method of claim 2 , wherein the nonalcoholic claim 2 , antiviral remedy comprises vinegar.5. The method of claim 2 , wherein the nonalcoholic claim 2 , antiviral remedy comprises ascorbic acid.6. The method of claim 2 , wherein the nonalcoholic claim 2 , antiviral remedy comprises food grade acids (citric claim 2 , malic claim 2 , oxalic claim 2 , benoic claim 2 , quinic claim 2 , tannic claim 2 , the unique combination of ingredients found in fresh ginger claim 2 , and any other food grade acid).7. The method of claim 1 , wherein the nonalcoholic claim 1 , antiviral remedy comprises citrus fruit (orange claim 1 , mandarin claim 1 , lemon claim 1 , lime claim 1 , etc.).8. The method of claim 2 , wherein the nonalcoholic claim 2 , antiviral remedy comprises honey.9. The method of claim 2 , wherein the ...

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07-01-2016 дата публикации

A COMPOSITION FOR IMPROVING JOINT HEALTH, OR FOR PREVENTING AND TREATING RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS

Номер: US20160000844A1
Принадлежит:

The present invention relates to a composition for helping with joint health or preventing, alleviating or treating rheumatoid arthritis and osteoarthritis, which is based on the results of tests conducted using an inflammatory cell model, an osteoarthritis animal model and an acute arthritis animal model. 1. A composition for helping with joint health or preventing , alleviating or treating rheumatoid arthritis and osteoarthritis , which contains , as an active ingredient:an extract mixture obtained by extracting each of Kalopanacis Cortex, Chaenomelis Fructus, Angelicae Gigantis, Zingiberis Rhizoma Crudus, Raphani Semen and Saururi Herba to prepare extracts, and mixing the extracts with one another at a mixing ratio of 150-250 parts by weight of the Kalopanacis Cortex extract: 650-750 parts by weight of the Chaenomelis Fructus extract: 650-750 parts by weight of the Angelicae Gigantis extract: 50-150 parts by weight of the Zingiberis Rhizoma Crudus extract: 50-150 parts by weight of the Raphani Semen extract: 150-250 parts by weight of the Saururi Herba extract; ora dry extract mixture obtained by drying each of the extracts and mixing the dried extracts with one another at the above mixing ratio; or a mixed extract obtained by mixing Kalopanacis Cortex, Chaenomelis Fructus, Angelicae Gigantis, Zingiberis Rhizoma Crudus, Raphani Semen and Saururi Herba with one another at the above mixing ratio to prepare a mixture, and extracting the mixture.2. The composition of claim 1 , which has effects on inhibition of inflammatory cytokines and matrix metalloproteinases (MMPs) claim 1 , relief of inflammation and pain claim 1 , enhancement of activity of cartilage formation factors claim 1 , and normalization of a joint structure.3. The composition of claim 1 , wherein a number of times the extraction is performed when each of the extracts or mixed extract is prepared is two or more.45-. (canceled)6. A pharmaceutical composition for alleviating or treating rheumatoid ...

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07-01-2016 дата публикации

Bioactive Compositions From Fruit and Methods for Their Production

Номер: US20160000848A1
Принадлежит:

The present invention relates to bioactive fractions (ingredients) derived from fruit juices. The bioactive fractions are either free of or substantially free of patulin and protein. Further, the bioactive fractions have antioxidant, free radical scavenging, moisturizing and buffering properties. The present invention also relates to a method for isolating bioactive fractions that are derived from fruit juices and are free or substantially free of protein and patulin. The present invention also relates to a method for preparing a bioactive fractions derived from fruit juices that are stabilized and are either free of or substantially free of patulin and protein. 1. A bioactive fraction derived from fruit , wherein said fraction is substantially free of patulin and protein.2. The bioactive fraction of wherein said fruit is selected from peaches claim 1 , pears claim 1 , bananas claim 1 , plums claim 1 , apples claim 1 , pineapples claim 1 , apricots claim 1 , cherries claim 1 , grapes claim 1 , blueberries claim 1 , raspberries claim 1 , blackberries claim 1 , cranberries claim 1 , tangerines claim 1 , prickly pears claim 1 , nectarines claim 1 , pomegranates claim 1 , oranges claim 1 , grapefruit claim 1 , tomatoes claim 1 , and combinations or mixtures thereof.3. The bioactive fraction of wherein said fraction comprises less than 25 microgram/kg patulin and less than 0.1% total protein content.4. The bioactive fraction of wherein said fraction is derived from apple.5. A composition comprising the bioactive fraction of wherein the composition is a leave-on product selected from the group consisting of cream claim 1 , dressing claim 1 , gel claim 1 , lotion claim 1 , ointment claim 1 , liquid claim 1 , a spray applicator claim 1 , and combinations thereof claim 1 , or a wash-off product selected from the group consisting of hand dishwashing detergent claim 1 , liquid hand soap claim 1 , bar soap claim 1 , body wash claim 1 , shampoo claim 1 , general purpose cleanser ...

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07-01-2016 дата публикации

COMPOSITION FOR REMEDYING OR TREATING RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS

Номер: US20160000849A1
Принадлежит:

The present invention relates to the composition according to the present invention, which has not only the effect of suppressing inflammation and pain, which are the common symptoms of acute and chronic arthritis, but also the effect of alleviating movement disorders, which are the symptoms of chronic arthritis. 1. A composition for alleviating or treating rheumatoid arthritis and osteoarthritis , which contains , as an active ingredient , an extract obtained by mixing a first extract , prepared by extracting 350-450 parts by weight of Kalopanacis Cortex , 350-450 parts by weight of Chaenomelis Fructus and 50-150 parts by weight of purified Aconiti Lateralis Preparata Radix , with a second extract prepared by extracting 150-250 parts by weight of Raphani Semen and 50-150 parts by weight of Atractylodis Rhizoma , wherein the extract is not cytotoxic to chondrocytes and synovial cells , and has anti-inflammatory and pain-relieving effects on arthritis patients and an effect of alleviating movement disorders in chronic arthritis patients.2. The composition of claim 1 , wherein an extraction solvent for the first extract is 40-60 wt % alcohol claim 1 , and an extraction solvent for the second extract is water.3. The composition of claim 1 , wherein a number of times each of the first extract claim 1 , the second extract and the mixed extract is extracted is two or more.45-. (canceled)6. A dry extract formulation for alleviating or treating rheumatoid arthritis and osteoarthritis claim 1 , which is prepared by concentrating and drying claim 1 , contains:an extract obtained by mixing a first extract, prepared by extracting 350-450 parts by weight of Kalopanacis Cortex, 350-450 parts by weight of Chaenomelis Fructus and 50-150 parts by weight of purified Aconiti Lateralis Preparata Radix, with a second extract prepared by extracting 150-250 parts by weight of Raphani Semen and 50-150 parts by weight of Atractylodis Rhizoma, wherein the extract is not cytotoxic to ...

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07-01-2016 дата публикации

MEDICINAL COMPOSITION FOR LIVER DISEASES

Номер: US20160000850A1
Принадлежит:

The invention provides a composition containing extracts from bunge, pentaphyllummak, Chinese magnoliavine, extract piece, pollen pini, and semen and methods of and using the same. 1. A composition for treating , preventing or ameliorating a liver disease , comprising{'i': 'salvia miltiorrhiza', 'an extract from bunge;'}{'i': 'cordyceps', 'an extract from extract piece;'}{'i': 'persicae', 'an extract from semen ; and'}{'i': 'gynostemma', 'an extract from at least one of pentaphyllummak, Chinese magnoliavine and pollen pini.'}2salvia miltiorrhiza. The composition of claim 1 , wherein the extract from bunge has a percentage in the range between about 25 and about 40 wt %.3. The composition of claim 1 , comprising:{'i': 'salvia miltiorrhiza', 'the extract from bunge in a range between about 25 and about 40 wt %,'}{'i': 'gynostemma', 'the extract from pentaphyllummak in a range between about 20 and about 35 wt %,'}the extract from Chinese magnoliavine in a range between about 5 and about 12 wt %,{'i': 'cordyceps', 'the extract from extract piece in a range between about 12 and about 20 wt %,'}the extract from pollen pini in a range between about 5 and 12 wt %, and{'i': 'persicae', 'the extract from semen in a range between about 5 and about 12 wt %.'}4. The composition of claim 1 , comprising:{'i': 'salvia miltiorrhiza', 'the extract from bunge in about 38 wt %,'}{'i': 'gynostemma', 'the extract from notoqinsenosides of pentaphyllummak in about 25 wt %,'}the extract from chinese magnoliavine in about 6 wt %,{'i': 'cordyceps', 'the extract from extract piece in about 19 wt %,'}the extract from pollen pini in about 6 wt %, and{'i': 'persicae', 'the extract from semen in about 6 wt %.'}5. The composition of claim 3 , wherein{'i': 'salvia miltiorrhiza', 'the extract from bunge has a content of salvianolic acid 2.5-10 wt %,'}{'i': 'chinensis', 'the extract from fructus schisandrae has a content of schisandrin 0.3-2.0 wt %,'}{'i': 'cordyceps', 'the extract from extract piece ...

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04-01-2018 дата публикации

Phosphatidylserine-Containing Diet Supplement Aids With Melatonin Anti-Catabolic Dietary Nutrients

Номер: US20180000881A1
Автор: Fritz Bob
Принадлежит:

A supplement includes plant-derived phosphatidylserine in a physiologically beneficial amount and at least one plant-based concentrate or extract which promotes a melatonergic benefit. 1. A supplement , comprising:phosphatidylserine; anda tart cherry component.2. The supplement of claim 1 , wherein the phosphatidylserine is a plant-derived phosphatidylserine.3. The supplement of any one of - claim 1 , wherein the plant-derived phosphatidylserine is a soy-derived phosphatidylserine (“SDPS”).4. The supplement of any one of - wherein the phosphatidylserine constitutes between about 10% and about 35% by mass of the supplement.5. The supplement of any one of - claim 1 , wherein the supplement includes about 30 mg to about 130 mg of SDPS.6. The supplement of any one of - claim 1 , wherein the tart cherry component is any one of dried tart cherry claim 1 , tart cherry powder claim 1 , and tart cherry extract.7. The supplement of any one of - claim 1 , wherein the tart cherry component constitutes between about 10% and about 70% by mass of the supplement.8. The supplement of any one of - claim 1 , wherein the supplement includes about 30 mg to about 250 mg of tart cherry.9. The supplement of any one of - claim 1 , further comprising divalent magnesium.10. The supplement of claim 9 , wherein the divalent magnesium is supplied as an orotate salt.11. The supplement of or claim 9 , wherein the divalent magnesium constitutes between about 20% and about 60% by mass of the supplement.12. The supplement of any one of - claim 9 , wherein the supplement includes about 70 mg to about 250 mg of divalent magnesium.13. The supplement of any one of - claim 9 , further comprising a feverfew component.14. The supplement of claim 13 , wherein the feverfew component constitutes between about 5% and about 20% by mass of the supplement.15. The supplement of or claim 13 , wherein the supplement includes about 15 mg to about 100 mg of the feverfew component.16. The supplement of any one of - ...

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13-01-2022 дата публикации

PLANT TISSUE-DERIVED NANOPARTICLES AND FOOD POWDERS

Номер: US20220008349A1
Принадлежит: PSIGRYPH INC.

Provided herein are nanoparticles including self-assembled cellular components derived from a homogenized plant tissue. Also provided are food powders and other related compositions. Methods for preparing such nanoparticles and food powders, as well as uses thereof in the treatment or prevention of diseases or disorders in a subject and/or as delivery vehicles are also described. 1. A nanoparticle comprising self-assembled cellular components derived from a homogenized plant tissue , the cellular components comprising one or more structural carbohydrates or cleavage products thereof , wherein lipids are not a structural component of the nanoparticle.2. The nanoparticle of claim 1 , wherein the nanoparticle is substantially lipid-free.3. The nanoparticle of or claim 1 , wherein the nanoparticle comprises pectin claim 1 , hemicellulose claim 1 , peptide and/or protein claim 1 , an organic acid claim 1 , at least one polyphenol claim 1 , cleavage products thereof claim 1 , or any combination thereof.4. The nanoparticle of any one of - claim 1 , wherein the nanoparticle comprises:a pectin-based inner core;an intermediate layer surrounding the inner core, the intermediate layer comprising macromolecules of pectin and hemicellulose and/or cleavage products thereof, polyphenol, and organic acid; anda fibrillated outer layer comprising macromolecular carbohydrate and protein, optionally formed from catabolism during ripening and/or during homogenization of the plant tissue.5. The nanoparticle of or claim 1 , wherein the organic acid comprises malic acid claim 1 , ascorbic acid claim 1 , or both.6. The nanoparticle of any one of - claim 1 , wherein the polyphenol comprises an anthocyanin.7. The nanoparticle of any one of - claim 1 , wherein the cellular components comprise those liberated from the plant tissue during ripening or during homogenization of ripened fruit claim 1 , which are capable of self-assembling into the nanoparticle.8. The nanoparticle of any one of - ...

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14-01-2016 дата публикации

Traditional Chinese medicine complex composite for significantly improving high density lipoprotein concentration in serum and preparation method thereof

Номер: US20160008406A1
Автор: Xiangyu Gao, Zhuangcun Gao
Принадлежит: Xiangyu Gao, Zhuangcun Gao

A traditional Chinese medicine complex composite for significantly improving high density lipoprotein (HDL) concentration in serum, includes: a tablet which includes 30%-50% hawthorn from north China, 10%-30% radix aucklandiae , 10%-30% radix glehniae and 10%-30% ligusticum wallichii ; and a powder which includes 40%-60% beef, 15%-35% bovine sinew, 15%-35% pigskin and 0.5%-2.5% Chinese-date. The tablet is prepared by decocting and boiling the raw material medicine with water, and the powder is prepared by catalytic hydrolysis with an enzyme, the pigskin in the powder can be replaced with bovine skin or donkey skin, and the bovine sinew can be replaced with bovine tendon.

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14-01-2016 дата публикации

Plant and Animal Extracts and Related Methods

Номер: US20160008417A1
Автор: Christopher VANDECAR
Принадлежит: Individual

The present disclosure is drawn to methods for producing natural extracts utilizing fulvic acid solutions as well as the extracts produced utilizing the disclosed methods. The method provides for selecting natural material(s) for extraction and contacting the natural material with a fulvic acid solution. In some embodiments the contacting can occur by pouring, dripping, sprinkling, submersing, or substantially submersing the natural material with the fulvic acid solution.

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14-01-2021 дата публикации

Compositions and methods for treating diarrheal diseases

Номер: US20210008028A1
Принадлежит: Vanessa Research Inc

Provided is a composition for the treatment of diarrheal disease, comprising a polyphenol-rich extract of a mixture of 80-20% by weight of blueberry or bilberry from Vaccinium cyanococcus spp., Vaccinium myrtillis spp., or both; and 20-80% by weight of sloe berry from Prunus spinosa spp. Other compositions, and methods of making and using the compositions for the treatment of diarrheal disease are disclosed.

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11-01-2018 дата публикации

COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING PULMONARY HYPERTENSION

Номер: US20180008662A1
Принадлежит:

The present invention provides a method of treating and/or preventing pulmonary hypertension in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a bioactive peptide preparation derived from at least one botanical source. 1Rosa damascena, Juglans nigra, Syzygium aromaticum, Inonotus obliquus, Camellia sinensis, Hypericum perforatum, Forsythia suspensa, Scutellaria laterifloraVerbena hastata.. A method of treating or preventing pulmonary hypertension in a subject , the method comprising administering to the subject in need thereof a therapeutically effective amount of a bioactive peptide preparation comprising an extract from at least one plant species selected from the group consisting of , and2. The method of claim 1 , wherein the preparation inhibits or scavenges reactive oxygen species in the subject.3. The method of claim 1 , wherein the preparation treats or alleviates one or more pulmonary hypertension symptoms selected from the group consisting of shortness of breath claim 1 , fatigue claim 1 , chest pressure claim 1 , chest pain claim 1 , abdominal pain claim 1 , racing pulse claim 1 , heart palpitations claim 1 , poor appetite claim 1 , nausea claim 1 , lightheadedness claim 1 , fainting claim 1 , dizziness claim 1 , swelling claim 1 , cyanosis claim 1 , abnormal blood pressure claim 1 , and chronic cough.4. The method of claim 1 , wherein the preparation comprises a plant species extract that is insoluble in at least one solvent selected from the group consisting of trichloroacetic acid claim 1 , acetone claim 1 , methanol claim 1 , an ammonium acetate solution claim 1 , and any combinations thereof.5. The method of claim 1 , wherein the preparation comprises a plant species extract that is soluble in at least one selected from the group consisting of phenol and sodium dodecyl sulfate (SDS).6. The method of claim 1 , wherein the preparation comprises a plant extract produced through a ...

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10-01-2019 дата публикации

BIOMEDICALLY ACTIVE AND DELIVERY SITE SPECIFIC CAPSULE-IN-CAPSULE LIVER SUPPLEMENT APPARATUS AND METHOD OF USE THEREOF

Номер: US20190008780A1
Автор: Perry Bruce
Принадлежит:

The invention comprises a biomedically active/delivery site specific capsule-in-capsule liver supplement and method of use thereof. A first set of constituents, of an outer capsule, of a capsule-in-capsule liver supplement, comprises one or more of choline and phosphatidylcholine; a second set of constituents, of an inner capsule, comprise one or more of methionine, glycyrrhetinic acid, silymarin, and phosphatidylcholine; and either capsule optionally contains one or more liver aiding/regulating natural products, where the outer capsule dissolves in the stomach and the inner capsule dissolves in the small intestine. Thus, the dual dissolution process in controlled environments results in complementary and synergistic delivery of liver regulating molecules in a bioavailable form ready for transport through the wall of the small intestine. Further, constituents of the capsule-in-capsule liver supplement include multiple inputs into the methionine cycle, which facilitates/synergistically aids the body's use of the methionine cycle, such as in liver regulation. 1. A method for aiding regulation of a liver of a human body , comprising the steps of: [ an outer casing chemically configured to dissolve at a pH<4.0 during use in the stomach; and', 'at least 100 mg of choline, said choline comprising a quaternary ammonium salt of a trimethylethanolammonium cation and a counter anion stable at the pH<4 in the stomach;', 'a first set of constituents emulsified in a first portion of phosphatidylcholine and contained within said outer casing, said first set of constituents comprising], 'an outer capsule comprising, an outer enteric coating stable at the pH<4 in the stomach and configured to dissolve at a pH>6 in the small intestine; and', at least 100 mg of S-adenosylmethionine;', 'at least 100 mg of glycyrrhetinic acid; and', 'at least 50 mg of silymarin;, 'a second set of constituents emulsified in a second portion of phosphatidylcholine and contained within said enteric ...

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10-01-2019 дата публикации

Method Of Treatment Of Insulin-Resistance Diabetes Mellitus

Номер: US20190008917A1
Автор: Lee Chen-Yu, LIAO Yan-Chih
Принадлежит:

The present invention is directed to a therapeutic method of treatment of diabetes mellitus, particularly diabetes which acquires insulin resistance, comprising administering a therapeutically effective amount of Chinese herbal medicine to a subject in need. The Chinese herbal medicine is the decocting extract including the mixture of raw oyster shell powder, raw Os Draconis, Haematitum, Magnetitum, radix Achyranthis Bidentatae, rhizoma Dioscoreae, radix Paeoniae Rubra, radix Rehmanniae, and semen Platycladi. 1. A method of treatment of insulin-resistant diabetes mellitus , comprising administering a therapeutically effective amount of Chinese herbal medicine to a subject in need;wherein the Chinese herbal medicine is an extract of a first mixture comprising raw oyster shell powder, raw Os Draconis, Haematitum, Magnetitum, radix Achyranthis Bidentatae, rhizoma Dioscoreae, radix Paeoniae Rubra, radix Rehmanniae, and semen Platycladi.2. The method as claimed in claim I , wherein the Chinese herbal medicine is prepared by following steps:providing the first mixture;mixing the first mixture and water to form a second mixture;heating the second mixture to obtain a crude extract; andfiltering the crude extract and retaining the liquid, to obtain the Chinese herbal medicine.3. The method as claimed in claim 1 , wherein the Chinese herbal medicine is the extract of the first mixture comprising 4-6 parts by weight of raw oyster shell powder claim 1 , 4-6 parts by weight of raw Os Draconis claim 1 , 7-9 parts by weight of Haematitum claim 1 , 2-4 parts by weight of Magnetitum claim 1 , 4-6 parts by weight of radix Achyranthis Bidentatae claim 1 , 4-6 parts by weight of rhizoma Dioscoreae claim 1 , 4-6 parts by weight of radix Paeoniae Rubra claim 1 , 4-6 parts by weight of radix Rehmanniae claim 1 , and 3-5 parts by weight of semen Platycladi.4. The method as claimed in claim 3 , wherein the part by weight of the first mixture is 3.75 gram per part.5. The method as claimed in ...

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19-01-2017 дата публикации

AGENT FOR SEDATING RESPONSE TO EXTERNAL STIMULATION IN SKIN AND METHOD FOR SEDATING THAT RESPONSE

Номер: US20170014444A1
Принадлежит: SHISEIDO COMPANY, LTD

An object of the present invention is to provide an agent for sedating the response of skin to external stimulation. The aforementioned object was achieved by finding a component that promotes CD39 gene expression in Langerhans cells. More specifically, the present invention is based on the finding that the combination of carboxymethyl-beta glucan or a salt thereof polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater promotes CD39 gene expression. 1. A CD39 gene expression promoter , comprising three components consisting of carboxymethyl-beta glucan or a salt thereof , polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater.2. An agent for sedating response to external stimulation in skin , comprising three components consisting of carboxymethyl-beta glucan or a salt thereof , polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater.3. An agent for sedating skin immune response , comprising three components consisting of carboxymethyl-beta glucan or a salt thereof , polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater. The present invention relates to a pharmaceutical agent that reduces the response of the skin to external stimulation.The skin is an organ located on the outermost layer of the body, and is continuously exposed to stimulation from the outside such as ultraviolet rays, physical stimulation, chemical stimulation or biological invasion.The skin has a three-layer structure consisting of the epidermis, dermis and subcutaneous tissue, and among these, the epidermis of the outermost layer is composed of keratinocytes, Langerhans cells and melanocytes and the like, and functions to prevent water loss and entry of foreign bodies and to protect the body from ultraviolet rays and other elements of the external environment. Upon receiving external stimulation, keratinocytes release a stimulation response factor, and ...

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19-01-2017 дата публикации

Compositions, Methods, and Medical Compositions for Treatment of and Maintaining the Health of the Liver

Номер: US20170014461A1
Принадлежит: Unigen, Inc.

Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one extract, at least one gel powder, and at least one extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one extract enriched for at least one polymer or biopolymer, at least one gel powder enriched for at least one chromone, and at least one extract enriched for at least one lignan and organic acid. 1ArtemisiaAloeSchizandra. A composition for treatment of and maintaining the health of the liver , comprising a mixture of plant extracts , wherein the plant extracts comprise at least one extract , at least one gel powder , and at least one extract.2ArtemisiaAloeSchizandra. A composition for treatment of and maintaining the health of the liver , comprising a mixture of plant extracts from an extract enriched for at least one polymer or biopolymer , an gel powder enriched for at least one chromone , and a extract enriched for at least one lignan and organic acid.3ArtemisiaSchizandra. The composition of claim 1 , wherein the extract and the extract are blended in a weight ratio from 4:1 to 1:4.4AloeArtemisiaSchizandra. The composition of claim 1 , wherein the gel powder are further blended with a mixture of and extracts in a weight percentage of about 5% to about 50%.5Artemisia, SchizandraAloe. The composition of claim 1 , wherein the mixture of and leaf gel powder is in a ratio of 8:4:3.6Artemisia. The composition of claim 2 , wherein the extract comprises 0.01% to 99.9% of biopolymers with molecular weight higher than 500.7ArtemisiaArtemisia absinthium, Artemisia abrotanumArtemisia afra, Artemisia annuaArtemisia arborescens, Artemisia asiatica, Artemisia campestris, Artemisia deserti, Artemisia iwayomogi, Artemisia ludoviciana, Artemisia vulgaris, ...

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21-01-2016 дата публикации

FORMULATION FOR ALLEVIATION OF KIDNEY STONE AND GALLSTONE SYMPTOMS AND METHOD OF TREATMENT

Номер: US20160015763A1
Автор: Barron Jon
Принадлежит:

A nutraceutical formula and food-based medicinal composition is provided comprising homeopathic ingredients in combination with traditional herbal and nutraceutical ingredients for relieving the symptoms associated with presence or formation of kidney stones and gallstones. The formulation includes ingredients balanced in a synergistic manner to elicit complementary effects which both reduce the symptoms of kidney stones and gallstones and provide the potential to eliminate their occurrence in the body and prevent future recurrence. Methods of making and using core medicinal formulations and food-based compositions are also described.

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21-01-2016 дата публикации

EXTERNAL-USE TRADITIONAL CHINESE MEDICINE FOR ICHTHYOSIS AND XERODERMIA, AND PREPARATION METHOD THEREOF

Номер: US20160015767A1
Автор: TONG Sen, Zhang Jian
Принадлежит:

An external-use curing and nursing traditional Chinese medicine for ichthyosis and xerodermia include, in parts by weight, for curing: 6-10 Cortex Dictamni, 5-8 Herba Lycopodii, 3-8 Flos Carthami, 3-8 Herba speranskiae tuberculatae, 6-10 Herba Menthae, 4-8 Folium Artemisiae Argyi, 3-6 GONGGUI, 3-6 Fructus Kochiae, 3-6 Cortex erythrinae, 3-6 Herba Artemisiae, 3-6 3-6 3-8 Radix Paeoniae Rubra, 3-6 3-6 2-4 Herba Leonuri, 3-5 Radix Ginseng Rubra, and 4-8 Radix Bupleuri; and include, in parts by weight, for nursing: 3-6 Libosch, 3-6 3-6 Andr., 3-5 3-8 3-8 aloes, 10-30 3-5 5-14 FRUCTUS CORNI, 5-14 3-6 peach kernel, 3-6 tremella, and 1-3 Panax. It is convenient to use, pain free, no side effect, no anti-medicine reaction is produced, and it operates quickly and has significant therapeutic effect. 1. External-use traditional Chinese medicine for ichthyosis and xerodermia characterized by comprising external-use curing traditional Chinese medicine and external-use nursing traditional Chinese medicine , wherein parts by weight are as follows:{'i': Ramulus Mori', 'Bletilla striata', 'Rhizoma Atractylodis', 'Asarum sieboldi, 'raw materials of the external-use curing traditional Chinese medicine comprises: Cortex Dictamni in 6-10 parts, Herba Lycopodii 5-8 in parts, Flos Carthami in 3-8 parts, Herba speranskiae tuberculatae in 3-8 parts, Herba Menthae in 6-10 parts, Folium Artemisiae Argyi in 4-8 parts, GONGGUI in 3-6 parts, Fructus Kochiae in 3-6 parts, Cortex erythrinae in 3-6 parts, Herba Artemisiae in 3-6 parts, in 3-6 parts, in 3-6 parts, Radix Paeoniae Rubra in 3-8 parts, in 3-6 parts, in 3-6 parts, Herba Leonuri in 2-4 parts, Radix Ginseng Rubra in 3-5 parts, and Radix Bupleuri in 4-8 parts; and'}{'i': Rehmannia glutinosa', 'Rehmannia glutinosa', 'Paeonia suffruticosa', 'Alisma plantago aquatica', 'Ophiopogon japonicus', 'Astragalus membranaceus', 'Poria cocos', 'Rhizoma Dioscoreae, 'raw materials of the external-use nursing traditional Chinese medicine comprising: ...

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17-01-2019 дата публикации

Agent for Activating Astrocyte Glucose Metabolism

Номер: US20190015469A1
Принадлежит: KAO CORPORATION

Provided is a material effective for improving the activity of nerves in the brain or for preventing or ameliorating brain dysfunction. An agent for activating astrocyte glucose metabolism, brain nerve cells activating agent, a brain hypofunction suppressing agent, a brain function improving agent, or an agent for preventing or ameliorating brain dysfunction comprising, as an active ingredient, one or more selected from the group consisting of hydrophobic solvent extracts of tien-cha, rooibos, grape and black tea. 122.-. (canceled)23. A method for activating astrocyte glucose metabolism in a subject , the method comprising administering an effective dose of a hydrophobic solvent extract of at least one selected from the group consisting of tien-cha , rooibos and black tea to the subject in need thereof.24. A method for activating brain nerve cells in a subject , the method comprising administering an effective dose of a hydrophobic solvent extract of at least one selected from the group consisting of tien-cha , rooibos and black tea to the subject in need thereof.25. A method for suppressing brain hypofunction in a subject , the method comprising administering an effective dose of a hydrophobic solvent extract of at least one selected from the group consisting of tien-cha , rooibos and black tea to the subject in need thereof.26. A method for improving brain function in a subject , the method comprising administering an effective dose of a hydrophobic solvent extract of at least one selected from the group consisting of tien-cha , rooibos and black tea to the subject in need thereof.27. A method for preventing or ameliorating brain dysfunction in a subject , the method comprising administering an effective dose of a hydrophobic solvent extract of at least one selected from the group consisting of tien-cha , rooibos and black tea to the subject in need thereof.28. The method according to claim 23 , wherein the astrocyte glucose metabolism activation is improved ...

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18-01-2018 дата публикации

MINERAL FUNCTIONAL WATER, METHOD FOR PRODUCING THE SAME

Номер: US20180016168A1
Автор: FURUSAKI Koichi
Принадлежит:

Provided is a method of producing mineral function water showing beneficial effects, such as antioxidant effects, or the like. The water including contains mineral-containing water (A) and mineral-containing water (B) according to a ratio of 1:5 to 1:20 (weight ratio), the mineral-containing water (A) containing first mineral components eluted from mineral-imparting material (A) containing: vegetation raw material, woody plant raw material, and sulfur raw material, the mineral-containing water (B) containing second mineral-containing water (B) containing the mineral component eluted from inorganic mineral-imparting material (B). 1. A method of producing mineral functional water , comprising:producing first mineral-containing water (A) according to the following first process (1): andproducing second mineral-containing water (B) according to the following second process (2):the mineral functional water containing the first produced mineral-containing water (A) and the second produced mineral-containing water (B) according to a ratio within a range of 1:5-1:20 (weight ratio),wherein the first process (1) includes:{'i': Betula platyphylla, Pinus,', 'Cryptomeria japonica;, 'immersing a conductive wire covered with insulator and mineral-imparting material (A) into water, the mineral-imparting material containing: woody plant raw material; vegetation raw material; and sulfur raw material, the vegetation raw material including: vegetation belonging to Asteraceae and vegetation belonging to Rosaceae, the woody plant raw material including at least one kind selected from a group consisting of Maple, and'}conducting DC electric current to the conductive wire to generate water flow around the conductive wire in the same direction as the DC electric current, applying ultrasonic vibration to the water, thereby forming raw mineral water solution (A); andirradiating far-infrared rays (wavelength of 6-14 micrometers) to the raw mineral water solution (A) to form mineral-containing ...

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21-01-2021 дата публикации

COMPOSITIONS FOR TREATING OBESITY

Номер: US20210015762A1
Автор: Kennedy J. Phillip
Принадлежит: Truetiva, Inc.

Embodiments of the invention are directed to compositions containing cannabinoids and bioenhancers for treating obesity, eating disorders, metabolic disorders, and other body weight related diseases and disorders, and methods for treating obesity, eating disorders, metabolic disorders, and other body weight related diseases and disorders by administering compositions containing cannabinoid and a bioenhancer. 1. A composition comprising a cannabinoid , bioenhancer , and a pharmaceutically acceptable carrier , excipient , diluent , reagent , or combinations thereof.2. The composition of claim 1 , wherein the cannabinoid has a concentration of about 20% (w/w) to about 1% (w/w) cannabinoid claim 1 , relative to a total amount of the composition.3. The composition of claim 1 , wherein the cannabinoid is selected from the group consisting of cannabidiol claim 1 , cannabidiol isomer claim 1 , cannabidiol analog claim 1 , or combinations thereof.4. The composition of claim 1 , wherein the bioenhancer has a concentration of about 0.05% (w/w) to about 20% (w/w) claim 1 , relative to a total weight of the composition.5. The composition of claim 1 , wherein the bioenhancer is a cyclic peptide.6. The composition of claim 1 , wherein the bioenhancer is piperidine or a piperidine derivative.7. The composition of claim 1 , further comprising an appetite suppressant.8. The composition of claim 7 , wherein the appetite suppressant has a concentration of about 0.05% (w/w) to about 20% (w/w) claim 7 , relative to the total amount of the composition.9. The composition of claim 7 , wherein the appetite suppressant is an extract selected from the group consisting of grapes claim 7 , pine claim 7 , cocoa claim 7 , tamarind claim 7 , tomato claim 7 , peanut claim 7 , almond claim 7 , apple claim 7 , cranberry and blueberry.10. A method for reducing the weight of a mammal comprising administering to the mammal a composition comprising a cannabinoid claim 7 , bioenhancer claim 7 , and a ...

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16-01-2020 дата публикации

ORALLY ADMINISTERED COMPOSITION FOR TREATING CYSTIC FIBROSIS, COPD, ASTHMA AND OTHER INFLAMMATORY CONDITIONS

Номер: US20200016228A1
Автор: Burch Lauranell H.
Принадлежит:

The invention relates to a new orally administered composition, which in present embodiments is a standardized phytochemical formulation but other embodiments may contain designed molecules. This formulation is capable of suppressing inflammation in a variety of disease conditions having an underlying inflammatory component, including but not limited to cystic fibrosis, COPD, asthma, and pancreatitis. It is an objective of the invention to provide a non-toxic therapy, which exhibits anti-oxidant anti-inflammatory properties without deleterious side effects. 1. A composition for oral administration that is suitable for the treatment of an inflammatory condition in animals or humans , consisting of combinations of five or more natural and/or synthetic molecules that have anti-inflammatory and/or CFTR modulating functions wherein one or more compounds within the composition is capable of the following functions:(1) Molecule(s) demonstrated to reduce inflammation in experimental models and/or in vivo.(2) Molecule(s) demonstrated in experimental systems and/or in vivo to act as corrector(s) of CFTR.(3) Molecule(s) demonstrated in experimental systems and/or in vivo to act as potentiator(s) of CFTR.(4) Molecule(s) demonstrated in experimental systems and/or in vivo to increase levels of cyclic AMP.(5) Molecule(s) demonstrated in experimental systems and/or in vivo to act as phosphodiesterase inhibitors.2. A composition according to claim 1 , wherein the compounds are selected from the classes of molecules consisting of: proanthocyanidins claim 1 , anthocyanins claim 1 , procyanidins claim 1 , catechins claim 1 , flavones claim 1 , flavone glycosides claim 1 , flavonoids claim 1 , isoflavones claim 1 , curcuminoids claim 1 , lipoic acids claim 1 , stilbenes and stilbenoids claim 1 , terpenes and terpenoids claim 1 , diterpenes claim 1 , triterpenes claim 1 , pentacyclic tri-terpenes claim 1 , carotenoids claim 1 , rutosides claim 1 , bithiazoles claim 1 , ...

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26-01-2017 дата публикации

COMPOSITIONS AND METHODS FOR COMBINATION INGREDIENT DELIVERY

Номер: US20170020811A1
Принадлежит:

Described herein are compositions, methods, and devices for relief of a cough, cold, sore throat, or allergy, or a related symptom. Also described herein are compositions, methods, and devices for the prevention, treatment and/or amelioration of a digestive illness or digestive discomfort, or a related symptom of either. 1. A composition comprising:a plurality of active pharmaceutical ingredients, wherein the plurality of pharmaceutical ingredients comprises an analgesic, anesthetic, antihistamine, antitussive, expectorant, decongestant, or demulcent, and wherein each of the active pharmaceutical ingredients provides relief for a cold, cough, or a sore throat, or a related symptom; anda plurality of botanical ingredients,wherein the plurality of active pharmaceutical ingredients and the plurality of botanical ingredients are present in a ratio by weight of about 1:32 to 1:65.2. The composition of claim 1 , wherein the plurality of active pharmaceutical ingredients and the plurality of botanical ingredients are present in a ratio by weight of about 1:64.310-. (canceled)11. The composition of claim 1 , wherein the analgesic claim 1 , anesthetic claim 1 , antihistamine claim 1 , antitussive claim 1 , expectorant claim 1 , decongestant claim 1 , or demulcent comprises acetaminophen claim 1 , ibuprofen claim 1 , ketoprofen claim 1 , aspirin claim 1 , naproxen claim 1 , benzocaine claim 1 , lidocaine claim 1 , dyclonine claim 1 , hexylresorcinol claim 1 , brompheniramine claim 1 , chlorpheniramine claim 1 , diphenhydramine claim 1 , dimenhydrinate guaifenesin claim 1 , phenylephrine claim 1 , pseudoephedrine claim 1 , glycerin claim 1 , or menthol.12. The composition of claim 1 , wherein the plurality of active pharmaceutical ingredients comprises at least three of: aspirin claim 1 , naproxen claim 1 , ibuprofen claim 1 , acetaminophen claim 1 , menthol claim 1 , benzocaine claim 1 , lidocaine claim 1 , dyclonine claim 1 , hexylresorcinol claim 1 , or ketoprofen.13. The ...

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26-01-2017 дата публикации

PHYTOCOMPLEXES EXHIBITING MULTIPLE, SYNERGISTIC ANTIOXIDANT ACTIVITIES USEFUL IN FOODS, DIETARY SUPPLEMENTS, COSMETICS AND PHARMACEUTICAL PREPARATIONS

Номер: US20170020948A1
Принадлежит: Nature's Sunshine Products, Inc.

Compositions comprising apple, grape, green tea, and olive extracts are presented herein. This synergistic formulations apple, grape, green tea, and olive extract are in amounts that provide a greater antioxidant activity or protein kinase modulating activity than provided by an equivalent amount of any one extract or a sum of the extracts. Further presented are methods of regulating oxidative stress, disease-associated protein kinase activity, and enhancing the therapeutic effect of a primary therapeutic agent. Also presented are methods of making an activity enhancing composition for regulating oxidative stress, disease-associated protein kinase activity, and enhancing the therapeutic effect of a primary therapeutic agent. 1. An oxidative stress modulating composition comprising:a combination of apple, grape, green tea, and olive extract in amounts that provide a greater antioxidant activity than provided by an equivalent amount of any one extract or a sum of the extracts.2Malus pumila.. The composition of claim 1 , wherein the apple extract comprises an extract of a species3Vitis vinifera.. The composition of claim 1 , wherein the grape extract comprises an extract of a species4Camellia sinensis.. The composition of claim 1 , wherein the green tea extract comprises an extract of leaves of a species5Olea europea europaea.. The composition of claim 1 , wherein the olive extract comprises an extract of a subspecies6. The composition of claim 1 , wherein at least one of the extracts in the composition is present in a different amount than an amount of at least one of another extract.7. The composition of claim 1 , wherein the apple claim 1 , grape claim 1 , green tea claim 1 , and olive extracts are present in the composition at a weight ratio of about 1:1:1:1.8. The composition of claim 1 , wherein the apple claim 1 , grape claim 1 , green tea claim 1 , and olive extracts are present in the composition at a weight ratio of about 6:1:3:19. The composition of claim 1 ...

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25-01-2018 дата публикации

COMPOSITION AND USE THEREOF IN MANUFACTURE OF PRODUCT FOR IMPROVING INTESTINAL FUNCTION

Номер: US20180021399A1
Принадлежит: INFINITUS (CHINA) COMPANY LTD.

The present invention relates to the technical field of health care products, in particular to a composition and use thereof in the manufacture of a product for improving intestinal function. The present invention provides a composition and use thereof in the manufacture of a product for improving intestinal function. In the present invention, probiotics, prebiotics, Crataegi Fructus and Dioscoreae Rhizoma are reasonably compounded, wherein each component acts synergistically, thus allowing the obtained composition to have good effects of preventing and/or treating diarrhea as well as improving intestinal flora. The efficacy thereof is significantly superior to (P<0.05) that of the Comparative Examples. 1. A composition , comprising probiotics , prebiotics , Crataegi Fructus and Dioscoreae Rhizoma.2. The composition according to claim 1 , wherein the mass ratio of the probiotics claim 1 , the prebiotics claim 1 , the Crataegi Fructus and the Dioscoreae Rhizoma is (2.0˜40.0): (30.0˜96.0):(1.0˜30.0):(1.0˜30.0).3LactobacillusBifidobacterium;. The composition according to claim 1 , wherein the probiotics are selected from and and the prebiotics are inulin.4LactobacillusBifidobacterium,LactobacillusBifidobacterium. The composition according to claim 3 , wherein the probiotics are and the mass ratio of the to the is (2.0˜20.0):(2.0˜20.0).5. The composition according to claim 1 , wherein the probiotics are added in an amount of 10CFU/g˜10CFU/g based on the total weight of the composition.6. A method for preventing and/or treating diarrhea claim 1 , comprising administering the composition of .7. The method according to claim 6 , wherein the diarrhea is antibiotic-associated diarrhea and/or diarrhea induced by spleen deficiency.8. A product for preventing and/or treating diarrhea claim 1 , comprising the composition of .9. A method for improving intestinal flora claim 1 , comprising administering the composition of .10. The method according to claim 9 , wherein the ...

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25-01-2018 дата публикации

VAGINAL DOUCHE WITH A COMPOSITION TO TIGHTEN THE VAGINA

Номер: US20180021503A1
Автор: Stewart Erica
Принадлежит:

A vaginal douche bottle with a composition of ingredients to tighten and prevention of growth of bad microorganisms in reproductive organs of human is provided. The vaginal douche bottle includes a removable cap, a middle portion, a bottom portion, and threads. The removable cap is adapted to remove from the vaginal douche bottle when a pipe adapter is required to be coupled with the vaginal douche bottle. The middle portion allows a user to hold the vaginal douche bottle. Threads are grooved on a top portion of the vaginal douche bottle to couple with a lower portion of the pipe adapter. The composition of ingredients filled in the vaginal douche bottle. When the middle portion of the vaginal douche bottle is pressed, the composition of ingredients comes out from the vaginal douche bottle through the adapter pipe and cleans the reproductive organs of the user. 1. A vaginal douche bottle with a composition of ingredients to tighten and prevention of growth of bad microorganisms in reproductive organs of human , wherein said vaginal douche bottle comprises:a removable cap that is adapted to remove from vaginal douche bottle when a pipe adapter is required to be coupled with said vaginal douche bottle;a middle portion that allows a user to hold said vaginal douche bottle;a bottom portion that provides a support to whole said vaginal douche bottle; anda plurality of threads that are grooved on a top portion of said vaginal douche bottle to couple with a lower portion of said pipe adapter;wherein said composition of ingredients filled in said vaginal douche bottle, wherein when said middle portion of said vaginal douche bottle is pressed, said composition of ingredients comes out from said vaginal douche bottle through said adapter pipe and cleans the reproductive organs of said user.2Echinacea, clendulaLactobacillus acidophilus,. The vaginal douche bottle of claim 1 , wherein said composition of ingredients comprises a mixture of apple cider vinegar claim 1 , purified ...

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10-02-2022 дата публикации

Compositions and methods for nutritional supplements

Номер: US20220040251A1
Автор: Hartley Pond
Принадлежит: DailyColors Health Inc

Compositions and methods are presented in which a plurality of chemically distinct polyphenols inhibit multiple enzymes in pathways associated with health and healthy ageing. Preferred compositions are derived from colored plant materials that are commonly found in the Mediterranean diet and provide the biochemical basis for the health benefits of the Mediterranean diet. Notably, the enzyme inhibition observed with the combined polyphenols was synergistic with respect to not one but a significant number of enzymes in the pathways associated with health and healthy ageing, thus providing an amplified desirable effect.

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22-01-2015 дата публикации

METHODS AND COMPOSITIONS FOR ENHANCING HAIR QUALITY USING BLACKBERRY EXTRACT

Номер: US20150024076A1
Принадлежит:

Compositions and methods for inducing hair growth and improving hair quality utilizing extracts of blackberry in an amount effective to induce hair growth when applied topically to an area of the skin on which hair growth is desired. 1Rubus fruticosus. A method of enhancing hair growth by applying to the scalp , the skin , the eyelashes , eyebrows , mustache region or beard region of a patient a topically active composition comprising a concentration of at least 90 mg extract/ml of solution but less than 300 mg/ml of a extract , which increase hair coverage to the scalp after daily application for at least seven days.2Rubus fruticosus. A method according to wherein said composition comprises a concentration of at least 120 mg/ml but less than 300 mg/ml of a extract.3Rubus fruticosus. A method according to wherein said composition comprises a concentration of at least 250 mg/ml but less than 300 mg/ml of a extract.4Rubus fruticosus. A topical composition for enhancing hair growth comprising at least 90 mg/ml less than 300 mg/ml of a extract.5Rubus fruticosus. A topical composition for enhancing hair growth comprising at least 120 mg/ml less than 300 mg/ml of a extract.6Rubus fruticosus. A topical composition for enhancing hair growth comprising at least 250 mg/ml less than 300 mg/ml of a extract.7. A topical composition according to wherein said composition further comprises skin care agents consisting of vitamins claim 4 , minerals claim 4 , proteins claim 4 , peptides claim 4 , fatty acids claim 4 , antioxidants claim 4 , anti-inflammatory agents claim 4 , darkening agents claim 4 , botanical extracts and mixtures thereof.8. A composition for enhancing hair growth on the scalp claim 4 , the skin claim 4 , the eyelashes claim 4 , eyebrows claim 4 , mustache region or beard region of a patient comprising a concentration of at least 90 mg extract/ml of solution but less than 300 mg/ml of a Rubus fruticosus extract and at least 1 weight percent of carbomer by weight of ...

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23-01-2020 дата публикации

METHOD FOR PREVENTING AND CONTROLLING BACTERIAL INFECTIONS IN SALMONID FISH USING QUILLAJA SAPONARIA EXTRACTS

Номер: US20200023026A1
Принадлежит:

The present invention discloses a new method for preventing and controlling bacterial diseases in salmonid fish using extracts, wherein said method comprises administering to salmonid fish an effective amount of a medicinal composition comprising a extract as active ingredient. 1Quillaja saponariaQuillaja saponaria. A method for preventing and controlling a bacterial disease in salmonid fish , wherein said method comprises administering to salmonid fish an effective amount of a medicinal composition comprising a extract as active ingredient and an appropriate excipient; wherein said extract contains saponins.2. The method according to claim 1 , wherein the medicinal composition is administered to the fish orally in a dose ranging from 0.9 to 12 mg saponins/kg of live weight of fish per day.3. The method according to claim 1 , wherein the medicinal composition is administered to the fish in combination with fish food.4. The method according to claim 1 , wherein the bacterial disease is caused by a Gram-negative bacteria.5Piscirickettsia salmonis.. The method according to claim 4 , wherein the Gram-negative bacteria is6. The method according to claim 1 , wherein the bacterial disease is caused by a Gram-positive bacteria.7Renibacterium salmoninarum.. The method according to claim 7 , wherein the bacteria is8Salmo salar, Salmo trutta, Salmo gairdnerii, Oncorhynchus mykissOncorhynchus kisutch.. The method according to claim 1 , wherein the salmonid fish is selected from the group consisting of and This application is a Divisional Application of U.S. application Ser. No. 15/543,977, filed on Jul. 14, 2017, which U.S. National Stage entry of PCT Application No. PCT/CL2016/050044, filed on Jul. 29, 2016, the contents of which are incorporated herein by reference.The present invention relates to the aquaculture industry, and particularly provides a new method for preventing and controlling bacterial diseases in salmonid fish using extracts of trees.It is widely known that ...

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28-01-2021 дата публикации

METHOD OF PRODUCING PHYSIOLOGICAL AND THERAPEUTIC LEVELS OF NITRIC OXIDE THROUGH AN ORAL DELIVERY SYSTEM

Номер: US20210023126A1
Принадлежит:

A composition and method of providing nitric oxide and nitrite therapy to patients whereby a therapeutic amount is bioavailable within approximately 30 minutes of administration. In embodiments of the invention, nitric oxide is produced in the oral cavity. 1. A delivery system comprising:at least one nitric oxide-producing component; anda dispersable medium adapted to be consumed in the oral cavity;wherein the nitric oxide-producing component is adapted to generate nitric oxide in vivo upon consumption of the dispersable medium.2. The delivery system of claim 1 , wherein the dispersable medium is dissolvable in the oral cavity.3. The delivery system of claim 1 , wherein the dispersable medium is dissolvable in about five minutes or less.4. The delivery system of claim 1 , wherein the delivery system is adapted to generate nitric oxide in the oral cavity.5. The delivery system of claim 1 , where the nitric oxide-producing component is adapted to generate nitric oxide in-vivo in response to dissolution of the delivery system in the gastro intestinal tract.6. The delivery system of claim 1 , wherein the delivery system is formed of a lozenge claim 1 , liquid claim 1 , powder claim 1 , solid claim 1 , semi-solid claim 1 , cream claim 1 , gel claim 1 , emulsion claim 1 , suspension claim 1 , heterogenic liquid claim 1 , film claim 1 , or topical.7. The delivery system of claim 1 , wherein the dispersable medium comprises one or more of a sugar claim 1 , dispersing agent claim 1 , flavor claim 1 , sweetener claim 1 , color claim 1 , alcohol claim 1 , maltodextren claim 1 , or filler.8. The delivery system of claim 1 , wherein the nitric oxide-producing component is comprised of a nitrite claim 1 , nitrate claim 1 , or reductase or a combination of nitrite claim 1 , nitrate and reductase.9. The delivery system of further comprising a barrier for preventing contact of two or more species of the nitric oxide-producing component.10. The delivery system of claim 9 , wherein ...

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29-01-2015 дата публикации

ORALLY ADMINISTERED PLASTID EXPRESSED CHOLERA TOXIN B SUBUNIT-EXENDIN 4 AS TREATMENT FOR TYPE 2 DIABETES

Номер: US20150030575A1
Автор: Daniell Henry
Принадлежит:

Disclosed herein are compositions and methods for treating Type II diabetes. The compositions comprise plant expressed Exendin 4. Particularly exemplified are plant derived compositions that include a CTB-EX4 conjugate that is bioencapsulated in chloroplasts. 134-. (canceled)35. A plant plastid comprising a plastid genome transformed with a heterologous DNA coding sequence encoding at least one fusion protein selected from the group consisting of CTB-Exendin , said coding sequence being integrated into said plastid genome such that said CTB-Exendin is expressed in and present in said plastid.36. An edible plant cell comprising the plastid of .37lactuca sativa. The plant cell of claim 36 , present in a plant selected from the group consisting of claim 36 , apple claim 36 , tomato and carrot.38. An edible composition comprising the plant cell of .39. A method of retarding the development of claim 38 , or treating Type II diabetes in a subject in need thereof comprising orally administering to said subject a composition as claimed in claim 38 , said composition comprising a CTB-Exendin polypeptide expressed in a chloroplast in a plant and a plant remnant.40. The method of claim 39 , wherein said plant remnant is rubisco.41Lactuca sativa. The method of claim 39 , wherein said plant is claim 39 , apple claim 39 , tomato or carrot.42Lactuca sativaLactuca sativa. A stable plastid transformation and expression vector for expression of the heterologous DNA coding sequence of in a plastid from claim 35 , said vector comprising an expression cassette comprising claim 35 , as operably linked components in the 5′ to the 3′ direction of translation claim 35 , a promoter operative in said plastid claim 35 , a selectable marker sequence claim 35 , a heterologous polynucleotide sequence coding for CTB-Exendin protein claim 35 , a transcription termination sequence functional in said plastid claim 35 , and flanking each side of the expression cassette claim 35 , flanking DNA ...

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04-02-2016 дата публикации

HERBAL COMPOSITIONS FOR TREATING PAIN AND SKIN DISORDERS

Номер: US20160030498A1
Принадлежит: RUPAK ENTERPRISES (P) LIMITED

The invention relates to herbal compositions having standalone preparations of two phytochemicals, Bakuchiol and Boswellic acid as well as synergistic combinations of Bakuchiol with either oil or boswellic acid or both. Bakuchiol in these compositions has assay by HPLC of greater than 50%, whereas boswellic acid is standardized to at least 20% of 3-o-Acetyl-11-keto-beta-boswellic acid. The compositions are either oral—for relief and remission of proliferative skin disorders or topical—for the treatment and management of pain. The invention further provides process of preparation of these compositions. The invention also relates to use of the compositions for treating pain or proliferative skin disorders and various dosage regimens. 171.-. (canceled)72Boswellia. A composition for the treatment/management of pain or skin disorders , comprising: from around 1% to around 15% of Bakuchiol by weight and further comprising oil or Boswellic acid or combinations thereof and optionally any other therapeutic agent.73. The composition according to claim 72 , wherein the composition is in or al or topical form.74. The composition according to claim 73 , wherein the composition is an oral composition.75. The composition according claim 74 , to claim 74 , wherein a ratio of Boswellic acid to Bakuchiol is from 30:1 to 1:5.76. The composition according to claim 75 , wherein the ratio of Boswellic acid to Bakuchiol is preferably from 15:1 to 1:2 and most preferably from 12:1 to 2:1.77. The composition according to claim 74 , wherein Boswellic acid has at least 20% of 3-o-Acetyl-11-keto p-Boswellic acid by weight.78. The composition according to claim 74 , wherein total of Bakuchiol and Boswellic acid is from 30-90% of the total composition by weight.79. The composition according to claim 73 , wherein the composition is a topical composition.80. The composition according to claim 79 , wherein the topical composition is a topical cream claim 79 , comprising one or more ingredients ...

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29-01-2015 дата публикации

PREBIOTIC MIXTURE

Номер: US20150030690A1
Принадлежит:

The present invention refers to a prebiotic mixture comprising at least one plant polysaccharide fibre and at least one of Propolis and/or and/or extracts, optionally comprising also and/or extracts. Moreover, the present invention also relates to said mixture for use in the preservation and/or in the restoration of the intestinal microbiota balance. 1Olea europaeaAloe veraThymus vulgarisAgrimonia eupatoria. A prebiotic mixture comprising at least one plant polysaccharide fibre and one of and/or Propolis and/or extracts and one of and/or extracts.2Linum usitatissimum. The prebiotic mixture according to claim 1 , wherein said at least one plant polysaccharide fibre is selected from the group consisting of inulin claim 1 , mucilages of Malvaceaes claim 1 , flea-worth fibres claim 1 , mucilages from claim 1 , glucomannan fibres claim 1 , spear grass fibres claim 1 , and gum arabic.3Cichorium intybusHelianthus tuberosusCynara scolymusTaraxacum officinalisArctium lappa.. The prebiotic mixture according to claim 2 , wherein said inulin is extracted from and/or and/or and/or and/or4Malva silvestrisAlthaea officinalis.. The prebiotic mixture according to claim 2 , wherein said mucilages of Malvaceaes are mucilages from and/or mucilages from5Plantago psyliumPlantago indicaPlantago ovata.. The prebiotic mixture according to claim 2 , wherein said flea-worth fibres are fibres from seeds or cuticle of and/or and/or6Amorphophallus konjac. The prebiotic mixture according to claim 2 , wherein said glucomannan fibres are fibres from tuber.7Cynodon dactylonElymus repens.. The prebiotic mixture according to claim 2 , wherein said spear grass fibres are fibres from rhizome of and/or8Althaea officinalisThymus vulgarisOlea europaea. The prebiotic mixture according to comprising inulin claim 7 , mucilages from claim 7 , gum arabic claim 7 , a extract claim 7 , a Propolis extract claim 7 , and an extract.9Althaea officinalisOlea europaeaThymus vulgarisAgrimonia eupatoria. The prebiotic ...

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01-02-2018 дата публикации

MALE AND FEMALE INFERTILITY HERBAL COMPOSITION

Номер: US20180028591A1
Автор: Ke Shaobin
Принадлежит:

An herbal composition that enhances and promotes fertility in both males and females by nourishing the kidney, regulating the liver and spleen, improving circulation of Qi and blood, and balancing the Yin and Yang through a unique composition consisting of natural herbs known in traditional Chinese medicine. The herbs create a synergy between each other that works to enhance fertility for both males and females. The composition consists of the following herbal ingredients mixed in varying weight percentages. goji berry, dodder seed, red sage root, green orange peel, processed fleece flower root, horny goat weed, codonopsis, raspberry, astragalus root, Chinese yam, white peony root, false daisy, mulberry, curcuma tuber, and cynomorium. The herbal ingredients are cleaned, purified and/or processed prior to formulation. The formulation process is at least partially dependent on the desired means of preparation and administering the composition. 1. An herbal composition for enhancing fertility in males and females , the composition comprising:about 3 to 15 weight percent Fructus Lycii, about 3 to 15 weight percent Semen Cuscutae, about 3 to 10 weight percent Radix Salviae Miltiorrhizae, about 1 to 5 weight percent Pericarpium Citri Reticulatae Viride preparata, about 3 to 15 weight percent Radix Polygoni Multiflori preparata, about 3 to 10 weight percent Herba Epimedii, about 3 to 15 weight percent Radix Codonopsis, about 3 to 15 weight percent Fructus Rubi, about 3 to 10 weight percent Radix Astragali, about 3 to 10 weight percent Rhizoma Dioscoreae, about 3 to 10 weight percent Radix Paeoniae Alba, about 3 to 10 weight percent Herba Ecliptae, about 5 to 10 weight percent Fructus Mori, about 3 to 10 weight percent Radix Curcumae, and about 3 to 10 weight percent Herba Cynomorii.2. The composition of claim 1 , wherein the composition is administered in at least one of the following ways: oral claim 1 , topical claim 1 , suppository claim 1 , intravenous claim 1 , ...

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29-01-2015 дата публикации

Method of treating, delaying and/or preventing alzheimer's disease

Номер: US20150031653A1
Принадлежит: SMARTFISH AS

The present invention relates to the treatment and/or prevention of Alzheimer's Disease or the symptoms associated therewith by daily administration of a drink formula comprising fresh marine omega-3 oil in an emulsion and resveratrol or derivatives thereof.

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04-02-2016 дата публикации

Growth supplement for efficient production of agricultural and livestock products

Номер: US20160031763A1
Принадлежит: WIZBIO Co Ltd

Provided is a growth supplement for efficient production of agricultural and livestock products, more specifically, a growth supplement for environment-friendly crop cultivation and livestock rearing to increase yields of crops and livestock, which is prepared by mixing specific amounts of antibiotic fruit juices, one or more sources of sugar, one or more sources of hydrogen carbonate, one or more sources of chloride ion and antifebrile vegetable juices depending on crops (species) and cultivation (livestock) conditions to feed the livestock or crops. The growth supplement is prepared by admixing and stirring antibiotic fruit juices in an amount of 2 to 10 parts by weight; the source of hydrogen carbonates in an amount of 1 to 4 parts by weight; the source of chloride ion in an amount of 1 to 4 parts by weight; and antifebrile vegetable juices in an amount of 2 to 8 parts by weight, based on 100 parts by the source of sugar.

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30-01-2020 дата публикации

ARONIA EXTRACT FOR ENHANCING REACTION TIME AND ATTENTION

Номер: US20200030400A1
Принадлежит:

This invention relates to the use of an berry extract or a composition comprising said extract for enhancing the reaction time, attention, concentration and psychomotor control of a mammal, more in particular a human. The composition comprising the extract is formulated for oral ingestion. 116.-. (canceled)17Aronia. A method for enhancing reaction time , psychomotor function , and/or attention of a mammal in need thereof , the method comprising administering an berry extract to the mammal.18Aronia. The method according to claim 17 , wherein the berry extract comprises more than 10% anthocyanins.19Aronia. The method according to claim 17 , wherein the berry extract comprises more than 10% anthocyanins claim 17 , more than 30% total polyphenols claim 17 , and/or 5% cyanidin-3-glucoside.20. The method according to claim 17 , wherein the mammal is a human.21. The method according to claim 17 , wherein the mammal is a healthy human.22. The method according to claim 17 , wherein the mammal is a human claim 17 , and wherein the human has an age of less than 60 years.23Aronia. The method according to claim 17 , wherein the berry extract is administered to enhance the reaction time of a human.24Aronia. The method according to claim 17 , wherein the berry extract is administered to enhance the psychomotor function of a human.25Aronia. The method according to claim 17 , wherein the berry extract is administered to enhance the attention of a human.26Aronia. A method for enhancing reaction time claim 17 , psychomotor function claim 17 , and/or attention of a mammal in need thereof claim 17 , the method comprising administering a composition comprising an berry extract to the mammal.27Aronia. The method according to claim 26 , wherein the composition comprises between 50-1200 mg of the berry extract.28Aronia. The method according to claim 26 , wherein the composition comprises the berry extract in combination with one or more additional ingredients selected from the group ...

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30-01-2020 дата публикации

ANTICANCER PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

Номер: US20200030401A1
Принадлежит:

The present invention discloses an anticancer pharmaceutical composition, comprising the following materials in parts by weight: 0.5-30 parts of fruits/leaves of 0.5-30 parts of fruits/leaves of 0.5-30 parts of peel/seeds of 0.5-30 parts of honey, 0.5-30 parts of flesh/pericarp of 0.5-30 parts of coconuts, 0.5-30 parts of pulp/peel of 0.5-30 parts of raw walnuts, 0.1-5 parts of 0.1-5 parts of 0.1-5 parts of seeds/leaves of 0.01-2 parts of and 0.01-2 parts of 1Rosa roxburghii,Phyllanthus emblica,Punica granatum,Garcinia mangostana,Citrus limon,Rhizoma gastrodiae,Lucid ganoderma,Moringa oleifera,Radix ranunculi ternatiRhizoma paridis.. An anticancer pharmaceutical composition , comprising the following materials in parts by weight: 0.5-30 parts of fruits/leaves of 0.5-30 parts of fruits/leaves of 0.5-30 parts of peel/seeds of 0.5-30 parts of honey , 0.5-30 parts of flesh/pericarp of 0.5-30 parts of coconuts , 0.5-30 parts of pulp/peel of 0.5-30 parts of raw walnuts , 0.1-5 parts of 0.1-5 parts of 0.1-5 parts of seeds/leaves of 0.01-2 parts of and 0.01-2 parts of2Rosa roxburghii,Phyllanthus emblica,Punica granatum,Garcinia mangostana,Citrus limon,Rhizoma gastrodiae,Lucid ganoderma,Moringa oleifera,Radix ranunculi ternatiRhizoma paridis.. The composition according to claim 1 , comprising the following materials in parts by weight: 1-20 parts of fruits/leaves of 1-20 parts of fruits/leaves of 1-20 parts of peel/seeds of 1-20 parts of honey claim 1 , 1-20 parts of flesh/pericarp of 1-20 parts of coconuts claim 1 , 1-20 parts of pulp/peel of 1-20 parts of raw walnuts claim 1 , 0.2-2 parts of 0.2-2 parts of 0.2-2 parts of seeds/leaves of 0.01-1 part of and 0.01-1 part of3Rosa roxburghiiRosa roxburghiiPhyllanthus emblicaPhyllanthus emblicaPunica granatumPunica granatumGarcinia mangostanaGarcinia mangostanaCitrus limonCitrus limonMoringa oleiferaMoringa oleifera. The composition according to claim 1 , wherein the fruits/leaves of comprise fresh or dried fruits and/or leaves; ...

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01-05-2014 дата публикации

Composition for accelerating change in muscle type

Номер: US20140120187A1
Принадлежит: Amorepacific Corp

The present invention provides a composition for accelerating a change in muscle type, increasing the amount of muscle, strengthening muscle, enhancing athletic abilities, reducing lipids, suppressing the accumulation of lipids, lowering blood sugar, controlling body weight or lowering body weight, containing a PPAR-δ promoter, an AMPK promoter and a PGC1-α promoter as an active ingredient

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11-02-2016 дата публикации

FRUIT AND VEGETABLE PRODUCT FOR CURING ORAL ULCER, AND PREPARATION METHOD THEREFOR

Номер: US20160037811A1
Принадлежит:

A fruit and vegetable product for curing oral ulcer, and a preparation method thereof. The fruit and vegetable product is made by mixing the following crude materials of different parts by weight: vegetables and/or fruits of 30-100 parts, food additives of 0-15 parts, probiotics powder of 0-5 parts, and recipients of 0-40 parts, the vegetables and fruits being cool and cold, cool and mild, and cold and mild; and the vegetables or fruits being cool, cold or mild in the theory of traditional Chinese medicine. 4. The fruit-vegetable food of claim 1 , wherein the vegetable and/or fruit of cool nature or cold nature comprises at least one selected from the group consisted of: pear claim 1 , watermelon claim 1 , banana claim 1 , grapefruit claim 1 , melon claim 1 , mulberry claim 1 , strawberry claim 1 , kiwi claim 1 , water chestnut claim 1 , asparagus claim 1 , radish claim 1 , rape claim 1 , spinach claim 1 , red beet claim 1 , eggplant claim 1 , tomato claim 1 , cherry tomato claim 1 , spinach claim 1 , rape claim 1 , water spinach claim 1 , bitter gourd claim 1 , cucumber claim 1 , celery claim 1 , mung bean claim 1 , lotus leaf claim 1 , kelp claim 1 , laver claim 1 , wakame claim 1 , volvox claim 1 , and spirulina; the vegetable and/or fruit of mild nature comprises at least one selected from the group consisted of: apple claim 1 , cabbage claim 1 , parsley claim 1 , and Chinese cabbage.5. The fruit-vegetable food of claim 1 , wherein the vegetable is vegetable containing greater than or equal to 0.1% of glucosinolate in their dry weight.6Bifidobacterium adolescentis, Lactobacillus Bifidobacterium, Bifidobacterium bifidum, Lactobacillus crispatus, Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus fermenti, Lactobacillus gasseri, Lactobacillus helveticus, Lactobacillus johnsonii, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus, ...

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11-02-2016 дата публикации

NITRITE FORMULATIONS AND THEIR USE AS NITRIC OXIDE PRODRUGS

Номер: US20160038533A1
Принадлежит:

Compositions comprising from about 40 weight parts to about 1000 weight parts of a botanical nitrate source; from about 20 weight parts to about 500 weight parts of a botanical source of nitrite reduction activity; and from about 4 weight parts to about 100 weight parts of a nitrite salt. Use of said composition in methods of reducing triglycerides or reducing C-reactive protein levels are also provided. 1. A method of reducing a patient's C-reactive protein level , comprising:administering to the patient a composition in a form of a lozenge dissolvable in the mouth, the composition comprising:from about 40 weight parts to about 1000 weight parts of a botanical nitrate source;from about 20 weight parts to about 500 weight parts of a botanical source of nitrite reduction activity;from about 20 weight parts to about 500 weight parts L-citrulline; andfrom about 4 weight parts to about 100 weight parts of a nitrite salt.2. The method of claim 1 , wherein the botanical nitrate source is selected from the group consisting of beet root claim 1 , artichoke claim 1 , holy basil claim 1 , gingko claim 1 , and mixtures thereof and is present at about 200 weight parts;{'i': 'Schisandra', 'the botanical source of nitrite reduction activity is selected from the group consisting of hawthorn berry, , green tea, beet root, pine bark, and mixtures thereof and is present at about 100 weight parts;'}the L-citrulline is present at about 100 weight parts; andthe nitrite salt is selected from the group consisting of sodium nitrite, potassium nitrite, and mixtures thereof and is present at about 20 weight parts;and the composition further comprises:about 1 weight part vitamin B12 in a form selected from the group consisting of methylcobalamin, cyanocobalamin, and mixtures thereof;about 100 weight parts vitamin C in a form selected from the group consisting of magnesium ascorbate, ascorbic acid, and mixtures thereof; andfrom about 50 weight parts to about 1500 weight parts of one or more ...

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11-02-2016 дата публикации

Nanofibre and Bioactive Compositions and Related Methods

Номер: US20160038611A1
Принадлежит:

Described herein are compositions in nanofibre form including one or more bioactive compounds releasably incorporated thereon. In one embodiment a composition is described comprising at least one nanofibre and at least one bioactive compound. The nanofibres are formed from a base material that is solubilised with the bioactive or bioactives in an aqueous based solvent solution and the base material and bioactives are together spun via electrospinning to form dry fibres with the bioactives chemically bonded to the nanofibres and the bioactives remaining stable during storage of the composition under ambient conditions substantially free of moisture. On exposure to moisture, the nanofibres dissolve, thereby releasing the bioactives. 1. A composition comprising:at least one nanofibre; andan effective amount of at least one bioactive compound;wherein the nanofibres are formed from a base material that is solubilised with the bioactive or bioactives in an aqueous based solvent solution and the base material and bioactives are together spun via electrospinning to form dry fibres; andwherein the bioactives are chemically bonded to the nanofibres and the bioactives remain stable during storage of the composition under ambient conditions substantially free of moisture; and,on exposure to moisture, the nanofibres dissolve, thereby releasing the bioactives.2. The composition as claimed in wherein the bioactives are stable for at least 8 days when stored at 20° C. in the absence of moisture.3. The composition as claimed in wherein the bioactives are covalently bonded to the nanofibres.4. The composition as claimed in wherein the bioactives are selected from: compounds that have at least one phenolic moiety; enzymes including a polypeptide with one or more tyrosine residues; and combinations thereof.5. The composition as claimed in wherein the bioactives are selected from the following plants claim 1 , parts thereof or extracts thereof: grape seed claim 1 , kiwifruit claim 1 , ...

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08-02-2018 дата публикации

MULTIVITAMIN CAPABLE OF BENEFICIAL GENE REGULATION THROUGH MICRORNA (MIRNA)

Номер: US20180036279A1
Автор: Gubler Daniel
Принадлежит:

The present invention includes compositions and methods for modifying the expression of microRNAs comprising: one or more plant secondary metabolites capable of beneficially regulating different genes in the human genome by modifying the expression of one or more microRNAs, wherein the one or more plant secondary metabolites are selected and provided in an amount selected to target the modification of one or more specific microRNA. 1. A composition for modifying the expression of microRNAs comprising:one or more plant secondary metabolites capable of beneficially regulating different genes in the human genome by modifying the expression of one or more microRNAs, wherein the one or more plant secondary metabolites are selected and provided in an amount selected to target the modification of one or more specific microRNAs.2. The composition of claim 1 , wherein the plant secondary metabolite is selected from at least 2 claim 1 , 3 claim 1 , 4 claim 1 , 5 claim 1 , 6 claim 1 , 7 claim 1 , 8 claim 1 , 9 claim 1 , or 10 plant secondary metabolites selected from epigallocatechin gallate; isoquercetin; folic acid; curcumin; hesperidin; grape polyphenols; sulporaphane; proanthocyanidins; apple polyphenols; or citrus bioflavonoids.3. The composition of claim 1 , wherein the composition is in capsule claim 1 , tablet claim 1 , gel claim 1 , powder claim 1 , pill claim 1 , granules claim 1 , solution claim 1 , suspension claim 1 , softgel claim 1 , gummy claim 1 , chewable claim 1 , liquid claim 1 , cake claim 1 , paste claim 1 , fast melting tablet claim 1 , film claim 1 , bead claim 1 , or bar form.4. The composition of claim 1 , wherein the composition further comprises at least one of one or more nutritional or therapeutic excipients claim 1 , salts claim 1 , corrigents claim 1 , fillers claim 1 , buffers claim 1 , diluents claim 1 , binders claim 1 , lubricants claim 1 , sweeteners claim 1 , coloring agents claim 1 , flavoring agents claim 1 , emulsifiers claim 1 , ...

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24-02-2022 дата публикации

Veterinary compositions and methods of use therefor

Номер: US20220054532A1
Автор: Colleen Smith, Diana Drumm
Принадлежит: Individual

Veterinary compositions comprising hyaluronic acid with a molecular weight of at least 800,000 Daltons and cannabidiol, veterinary compositions comprising hyaluronic acid with a molecular weight of at least 800,000 Daltons and cannabidiol Complex, and methods for treating ailments and/or symptoms of said ailments in non-human subjects in need thereof by administering an effective amount of such compositions.

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24-02-2022 дата публикации

PHARMACEUTICAL COMPOSITIONS AND USE THEREOF

Номер: US20220054572A1
Автор: REN Xuefeng, XIE Be
Принадлежит:

The present application relates to methods of preventing, treating or managing a respiratory disease and/or a viral infection (e.g., an influenza virus infection and COVID-19) using a pharmaceutical composition produced from one or more preparations of plant parts. Provided herein are the pharmaceutical compositions produced from the one or more preparations. Also provided herein are methods of producing the pharmaceutical composition from the one or more preparations. 1. A method of preventing , treating or managing a respiratory disease and/or a viral infection , comprising administering to a subject in need of such prevention , treatment , or management a pharmaceutical composition produced from one or more preparations comprising(i) a preparation of the grassy stem of Ephedra sinica Stapf;{'sub': ['4', '2'], '#text': '(ii) Gypsum ore (CaSO.2HO);'}(iii) a preparation of the seed (nut) of Semen Armeniacae Amarum; and/or(iv) a preparation of the dried root and rhizome of Glycyrrhiza uralensis Fisch., andwherein the pharmaceutical composition comprises a pharmaceutically acceptable carrier.2. The method according to claim 1 , wherein the respiratory disease and/or the viral infection is pneumonia claim 1 , an influenza virus infection claim 1 , or a coronavirus infection.36.-. (canceled)7. The method according to claim 2 , wherein the coronavirus infection is coronavirus disease 2019 (COVID-19).812.-. (canceled)13. The method according to claim 1 , wherein the method further comprises administering to the subject a second agent.14. The method according to claim 13 , wherein the second agent is an antiviral agent claim 13 , an anti-inflammatory agent claim 13 , a Janus kinase inhibitor claim 13 , a steroid hormone claim 13 , an immunosuppressive agent claim 13 , an agent targeting interleukin-6 receptor claim 13 , an antibacterial agent claim 13 , an anti-parasitic agent claim 13 , Traditional Chinese medicine claim 13 , stem cells claim 13 , convalescent plasma ...

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24-02-2022 дата публикации

PHARMACEUTICAL COMPOSITIONS AND USE THEREOF

Номер: US20220054573A1
Автор: REN Xuefeng, XIE Be
Принадлежит:

The present application relates to methods of preventing, treating or managing chronic obstructive pulmonary disease (COPD) and/or other obstructive lung diseases using a pharmaceutical composition produced from one or more preparations of plant parts. Provided herein are the pharmaceutical compositions produced from the preparations. Also provided herein are methods of producing the pharmaceutical compositions. 1. A method of preventing , treating or managing chronic obstructive pulmonary disease (COPD) , comprising administering to a subject in need of such prevention , treatment , or management a pharmaceutical composition produced from preparations comprising:{'i': 'Poria cocos', '(i) a preparation of the dried sclerotia of (Schw.) Wolf;'}and one or more of{'i': 'Semen armeniacae amarum', '(ii) a preparation of the seed (nut) of ; and'}{'i': 'Glycyrrhiza uralensis', '(iii) a preparation of the dried root and rhizome of Fisch.,'}wherein the pharmaceutical composition comprises a pharmaceutically acceptable carrier.2. The method according to claim 1 , wherein the COPD is caused by the condition of emphysema and/or chronic bronchitis.3. (canceled)4. The method according to claim 1 , wherein the pharmaceutical composition is administered via oral route.5. The method according to claim 1 , wherein the method further comprises administering to the patient a second agent.6. The method according to claim 5 , wherein the second agent is a bronchodilator claim 5 , a steroid claim 5 , a phosphodiesterase-4 inhibitor claim 5 , an antibiotic claim 5 , a mucoactive agent claim 5 , an anti-cancer agent claim 5 , an agent blocking interleukin (IL)-5 or its receptor claim 5 , or a combination thereof.7. (canceled)8. The method according to claim 1 , wherein the preparations comprise:{'i': 'Poria cocos', '(i) the preparation of the dried sclerotia of (Schw.) Wolf in an amount of 2 wt. % to 60 wt. % or 5 g to 35 g;'}and one or more of{'i': 'Semen armeniacae amarum', '(ii) the ...

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24-02-2022 дата публикации

PHARMACEUTICAL COMPOSITIONS AND USE THEREOF

Номер: US20220054574A1
Автор: REN Xuefeng, XIE Be
Принадлежит:

The present application relates to methods of preventing, treating or managing a respiratory disease and/or a viral infection (e.g., an influenza virus infection and COVID-19) using a pharmaceutical composition produced from one or more preparations of plant parts. Provided herein are the pharmaceutical compositions produced from the one or more preparations. Also provided herein are methods of producing the pharmaceutical composition from the one or more preparations. 1. A method of preventing , treating or managing a respiratory disease and/or a viral infection , comprising administering to a subject in need of such prevention , treatment , or management a pharmaceutical composition produced from preparations comprising:{'i': 'Illicium verum', '(i) a preparation of the fruit of ; and'}{'i': Sclerotium', 'Poria cocos, '(ii) a preparation of the dried of (Schw.) Wolf, in the weight ratio from 1:1 to 1:10, and'}wherein the pharmaceutical composition comprises a pharmaceutically acceptable carrier.2. The method according to claim 1 , wherein the respiratory disease is pneumonia.3. The method according to claim 1 , wherein the respiratory disease and/or the viral infection is an influenza virus infection.4. The method according to claim 3 , wherein the influenza virus is influenza virus A.5. The method according to claim 1 , wherein the respiratory disease and/or the viral infection is a coronavirus infection.6. The method according to claim 5 , wherein the coronavirus is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).7. The method according to claim 5 , wherein the coronavirus infection is coronavirus disease 2019 (COVID-19).8. The method according to any one of to claim 5 , wherein the method prevents the respiratory disease and/or the viral infection.9. A method of preventing claim 5 , treating or managing COVID-19 claim 5 , comprising administering to a subject in need of such prevention claim 5 , treatment claim 5 , or management a pharmaceutical ...

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07-02-2019 дата публикации

METHOD FOR TREATING MALIGNANT PLEURAL EFFUSION

Номер: US20190038698A1
Принадлежит:

The present invention is directed to a method for treating malignant pleural effusion comprising administering a first herbal medicine composition to a subject in need; wherein the first chinese herbal medicine is an extract of a first mixture comprising Macrocephalae, Herba Ephedrae, Fructus Jujubae, dried Langan, Stephaniae Tetrandrae, and Gastrodiae; powder; and a second mixture comprising 1. A method for treating malignant pleural effusion comprising:administering a first chinese herbal medicine to a subject in need;{'i': Poria, Grifola, Rhizoma Atractylodis, Rhizoma Alismatis, Semen Lepidii, Rhizoma Atractylodis', 'Fructus Crataegi,', 'Radix', 'Rhizoma', 'Ginseng, 'wherein the first chinese herbal medicine is an extract of a first mixture comprising Macrocephalae, Herba Ephedrae, Fructus Jujubae, dried Longan, Stephaniae Tetrandrae, and Gastrodiae; powder; and'}{'i': 'Radix Kansui, Euphorbia pekinensis, Flos Genkwa.', 'a second mixture comprising'}2. The method as claimed in claim 1 , wherein a preparation of the first chinese herbal medicine comprises:providing the first mixture;mixing the first mixture and water to form a third mixture;decocting the third mixture to obtain a crude extract;filtering the crude extract to remove a residue and obtain a liquid extract; and{'i': 'Ginseng', 'adding the powder and the second mixture to the liquid extract in order to obtain the first chinese herbal medicine.'}3Poria,Grifola,Rhizoma Atractylodis,Rhizoma Alismatis,Semen Lepidii,Rhizoma AtractylodisFructus Crataegi,RadixRhizoma. The method as claimed in claim 1 , wherein the first mixture comprises 6-10 parts by weight of 6-10 parts by weight of 6-10 parts by weight of 13-17 parts by weight of 13-17 parts by weight of 6-10 parts by weight of Macrocephalae claim 1 , 1-5 parts by weight of Herba Ephedrae claim 1 , 5-10 parts by weight of Fructus Jujubae claim 1 , 2-6 parts by weight of 6-10 parts by weight of dried Longan claim 1 , 2-6 parts by weight of Stephaniae ...

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07-02-2019 дата публикации

SEVEN-STAR TEA WITHOUT EXCIPIENT AND METHOD OF PREPARING THE SAME

Номер: US20190038699A1
Принадлежит:

The present invention relates to a seven-star tea without excipient. The seven-star tea comprises the following: Coicis Semen, Oryzae Fructus Germinatus, Triticum Aestivum, Herba Lophatheri, Fructus Crataegi, Ramulus Uncariae Cum Uncis, Periostracum Cicadae and Radix Et Rhizoma Glycyrrhizae, wherein the Triticum Aestivum is used as a forming agent in the seven-star tea. The method of preparing the seven-star tea comprises the following: weighing the medicinal materials according to the formula of seven-star tea; mixing the medicinal materials except for Triticum Aestivum together, decocting the resulting mixture with water 1-3 time(s), each time lasting for 0.5-2 hours, then combining the decoctions obtained from each time, filtering, and concentrating the resulting filtrate into a concentrated solution with relative density of 1.0-1.3 g/cm; pulverizing the weighed Triticum Aestivum into particles of 15-40 mesh size, then dispersing the concentrated solution obtained to the pulverized particles of Triticum Aestivum; fully drying the pulverized particles of Triticum Aestivum loaded with the concentrated solution, then packing the particles in a desired product form. The seven-star tea of the present invention is specially suitable for children, since it has the effects of promoting appetite and removing food stagnation, clearing heat and arresting convulsion, and long-term intake of sucrose or other excipients which are not beneficial for their health is avoided. 1. A seven-star tea without excipient , comprising: Coicis. Semen , Oryzae Fructus Germinatus , Triticum Aestivum , Herba Lophatheri , Fructus Crataegi , Ramulus Uncariae Cum Uncis , Periostracum Cicadae and Radix Et Rhizoma Glycyrrhizae , wherein the Triticum Aestivum is used as a forming agent in the seven-star tea.2. The seven-star tea without excipient according to claim 1 , wherein the seven-star tea comprises: 15-30% of Coicis Semen claim 1 , 15-30% of Oryzae Fructus Germinatus claim 1 , 15-25% of ...

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06-02-2020 дата публикации

NANOPARTICLES FOR DELIVERY OF CHEMOPREVENTIVE AGENTS

Номер: US20200038327A1
Принадлежит:

Disclosed herein are nanoparticle compositions and methods of use such as for chemoprevention of cancer, for example oral squamous cell carcinoma (OSCC). The nanoparticle composition comprises a Janus particle comprising at least two chemopreventive agents, wherein at least one of the chemopreventive agents is selected from freeze-dried black raspberries (BRB), a synthetic vitamin A analogue, N-acetylcysteine (NAC), and an anti-interleukin 6 agent. Methods for improving oral health comprising administering to a subject the nanoparticle compositions are also disclosed. 1. A nanoparticle composition comprising: a Janus particle comprising at least two chemopreventive agents , wherein at least one of the chemopreventive agents is selected from the group consisting of freeze-dried black raspberries (BRB) , a synthetic vitamin A analogue , N-acetylcysteine (NAC) , and an anti-interleukin 6 agent.2. The nanoparticle composition of claim 1 , wherein the at least two chemopreventive agents selected are BRB and fenretinide (4-HPR).3. The nanoparticle composition of claim 1 , wherein the at least two chemopreventive agents selected are 4-HPR and NAC.4. The nanoparticle composition of claim 1 , wherein the at least two chemopreventive agents selected are 4-HPR and tocilizumab.5. The nanoparticle composition of claim 1 , wherein the at least two chemopreventive agents selected are NAC and tocilizumab.6. The nanoparticle composition of claim 1 , wherein the Janus particle comprises poly(lactic-co-glycolic acid).7. The nanoparticle composition of claim 2 , wherein the concentration ratio of BRB and 4-HPR is between 1:1 and 1 claim 2 ,000:1.8. The nanoparticle composition of claim 1 , further comprising a mucoadhesive.9. The nanoparticle composition of claim 8 , wherein the mucoadhesive comprises lectin.10. The nanoparticle composition of claim 1 , further comprising a mucous penetration enhancer.11. The nanoparticle composition of claim 10 , wherein the mucous penetration ...

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06-02-2020 дата публикации

COMPOSITIONS CONTAINING PLANT EXTRACTS AND APPLICATIONS THEREOF

Номер: US20200038468A1
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Provided is a composition for reducing the fat content of fat-producing cells and applications thereof. The composition includes plant extracts such as a blueberry extract and a black tea extract. 1ginsengginseng. A composition comprising a plant extract , wherein the composition comprises a combination selected from the group consisting of a blueberry extract and a black tea extract , a blueberry extract and a green tea extract , a red wine extract and a black tea extract , a red wine extract and a green tea extract , a red wine extract and a Pu-erh tea extract , a red wine extract and a Four Seasons Spring tea extract , a red wine extract and a citrus extract , a red wine extract and a spinach extract , a red wine extract and a green coffee bean extract , a citrus extract and a broccoli sprout extract , a citrus extract and a red clover extract , a citrus extract and an aloe extract , a citrus extract and a rosemary extract , a citrus extract and a garlic extract , a citrus extract and a pepper extract , a citrus extract and a turmeric extract , a citrus extract and a wolfberry extract , a citrus extract and a extract , a citrus extract and apple polyphenols , a citrus extract and β-carotene , a citrus extract and lycopene , a spinach extract and a red clover extract , a spinach extract and a rosemary extract , a spinach extract and a garlic extract , a spinach extract and a turmeric extract , a spinach extract and a wolfberry extract , a spinach extract and a extract , a spinach extract and apple polyphenols , and a spinach extract and β-carotene.2. The composition of claim 1 , wherein the composition comprises one of the following combinations: at least 0.0625 mg/ml of the blueberry extract and at least 0.0625 mg/ml of any one of the black tea extract and the green tea extract.3. The composition of claim 1 , wherein the composition comprises one of the following combinations: at least 0.0625 mg/ml of the red wine extract and at least 0.0625 mg/ml of any one of ...

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12-02-2015 дата публикации

Pharmaceutical Composition for Treating Urinary Incontinence and Enuresis

Номер: US20150044308A1
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The present invention relates to a pharmaceutical composition for treating urinary incontinence and/or enuresis, which comprises at least 0.5-20 wt % of a mixture of flavonoids, 2-20 wt % of condensed tannins or proantocyanidins and 0.3-60 wt % of gamma aminobutyric acid (GABA), with respect to the total composition. Said composition additionally comprises at least 0% of a extract. The present invention also relates to the use of said composition for preparing a medicine for treating incontinence and/or enuresis, in particular enuresis in children, as well as in adults or the elderly who have urine leaks such as incontinence due to stress or urgency. 1. Pharmaceutical composition for treating urinary incontinence and/or enuresis comprising 0.5-20 wt % of a mixture of flavonoids , 2-20 wt % of condensed tannins or proantocyanidins and 0.3-60 wt % of gamma aminobutyric acid (GABA) , with respect to the total composition.2Humulus Lupulus. Composition according to claim 1 , additionally comprising at least 50% of a extract.3. Composition according to claim 1 , wherein the flavonoids are rutin.4. Composition according to claim 1 , additionally comprising Vitamin E and B.5. Composition according to claim 4 , wherein the Vitamin B is choline.6. Composition according to claim 2 , additionally comprising the following components expressed in percentages by weight claim 2 , such that the individual values of the percentages of the different components of the composition are such that the total of the composition never exceeds 100%:{'i': 'Humulus lupulus', '50-75% of extract,'}{'i': 'Humulus Lupulus', '2% of essential oil extract,'}20-50% of sweet almond oil,0.1-0.5% of tocopheryl acetate, and0.1-0.2% of ascorbyl palmitate.7. Composition according to claim 1 , wherein the pharmaceutical composition is administered in the form of an inhalable liquid claim 1 , patch claim 1 , tablet claim 1 , capsule claim 1 , injectable and/or gel.8. Composition according to claim 1 , wherein ...

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