Preparation method of trifluoroacetyl substituted indoline compound

The invention discloses a preparation method of a trifluoroacetyl-substituted indoline compound, which comprises the following steps: adding a palladium catalyst, a ligand, alkali, an additive, trifluoroethyl imidoacyl chloride and olefin into an organic solvent, reacting at 80 DEG C for 48 hours, and after the reaction is completed, performing post-treatment to obtain the trifluoroacetyl-substituted indoline compound. The preparation method has the advantages of simple operation, cheap and easily available initial raw materials, good substrate compatibility and diversified product structures, and can synthesize trifluoroacetyl substituted indoline compounds substituted by different types of groups through substrate structure design, so the operation is convenient, and the practicability of the method is widened.