28-01-1998 дата публикации
Номер: EP0821022A1
A poly(phenylene ether) resin composed of structural units represented by the general formula: (wherein R 1 , R 2 and R 3 represent each alkyl, cycloalkyl, etc. or H provided that two or more of R 1 , R 2 and R 3 do not represent H at the same time, or one of R 1 , R 2 and R 3 represents alkyl or H while the others together form a saturated ring, or R 1 , R 2 and R 3 together form an aromatic ring; A represents alkyl; p is an integer of from 3 to 5; and Y-represents a pharmaceutically acceptable acid residue and/or structural units represented by the general formula: wherein R 4 , R 5 and R 6 each represents alkyl, cycloalkyl, etc. or H provided that two or more of R 4 , R 5 and R 6 do not represent H at the same time, or one of R 4 , R 5 and R 6 , represents alkyl or H while the others together form a saturated ring, or R 4 , R 5 and R 6 together form an aromatic ring; and A, p and Y- have same meanings as defined above and structural units represented by the general formula: wherein R 7 and R 8 each represents alkyl, cycloalkyl, etc. or together form a saturated ring; q is an integer of from 3 to 20; and A, p, and Y- have same meanings as defined above wherein the sum of the contents of the structural units represented by the general formula (II) amounts to 40 to 96 % by mole and the content of the structural units represented by the general formula (III) amounts to 4 to 60 % by mole based upon the content of phenylene ether component and a process for producing the same. The poly(phenylene ether) resins have the effect of absorbing bile acids and are useful as cholesterol reducing agents.
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