16-05-2013 дата публикации
Номер: US20130123364A1
Принадлежит:
The present invention describes the use of N-(1-iminoethyl)-L-lysine for the manufacture of a medicament for the treatment of pulmonary alveolar damage or destruction in mammals, including in humans. 1. A pharmaceutical composition for the treatment of pulmonary alveolar damage and destruction comprising N-(1-iminoethyl)-L-lysine.2. The composition of claim 1 , wherein the composition is used for the treatment of mammals.3. The composition of claim 2 , wherein the composition is used for the treatment of humans.4. The composition of claim 1 , wherein the composition is administered orally claim 1 , by inhalation or by injection.5. The composition of claim 1 , wherein the N-(1-iminoethyl)-L-lysine is present as a salt claim 1 , ester or amide.6. A method of treatment of pulmonary alveolar damage or destruction claim 1 , the method comprising claim 1 , administering to a patient in need thereof claim 1 , a therapeutically effective amount of a pharmaceutical composition comprising N-(1-iminoethyl)-L-lysine or a salt or ester claim 1 , or amide thereof claim 1 , wherein administration of the pharmaceutical composition treats said pulmonary alveolar damage or destruction.7. The method of claim 6 , wherein the pharmaceutical composition is administered to mammals such as humans.8. The method of claim 6 , wherein the pharmaceutical composition is administered orally claim 6 , by inhalation or by injection. This Application is a continuation-in-part of PCT Application No. PCT/EP2011/061474, filed Jul. 7, 2011, which is incorporated herein by reference in its entirety as if fully set forth herein.The present invention concerns the use of N-(1-iminoethyl)-L-lysine for the manufacture of a medicament for the regeneration of alveoli in the lung.The main function of the lung is to supply the blood with oxygen and to simultaneously dispose carbon dioxide. This happens in alveoli, an anatomical structure in the lung parenchyma, being the terminal end of the respiratory tree. ...
Подробнее
