Temperature-stabilized storage systems with integral regulated cooling

In some embodiments, a regulated thermal transfer device for a storage container includes: a phase change material unit, the phase change material unit including one or more walls surrounding a phase-change material region, and an aperture in the one or more walls; a heat pipe with a first end positioned within the phase change material unit, and a second end; a thermoelectric unit thermally connected to the second end of the heat pipe; a heat sink connected to the thermoelectric unit, and positioned to radiate heat away from the thermoelectric unit; and an electronic controller operably connected to the thermoelectric unit; wherein the regulated thermal transfer device is of a size and shape to be positioned so that the phase change material unit is within a storage region of a temperature-stabilized storage container, and the thermoelectric unit is positioned adjacent to an external surface of the temperature-stabilized storage container.

PORT ACCESS VISUALIZATION PLATFORM

A medical system generally comprises a camera head, a beam, and a guide sheath. The camera head is connected to the beam which is bendable in a first direction and resists bending in a second direction opposite the first direction. The guide sheath slidably receives the beam, the beam extending through a distal end of the guide sheath such that the camera head projects from the distal end of the guide sheath. The guide sheath includes first and second sheath portions, and in an operative configuration the first sheath portion is angled relative to the second sheath portion to define a first bend. The beam is oriented relative to the guide sheath such that, as the beam is slid relative to guide sheath, the beam bends in the first direction through the first bend, and a projecting portion of the beam resists bending in the second direction. 1. A medical system for use intracorporeally to assist in surgical procedures beneath a tissue layer , the system comprising:a camera;a beam having a distal end attached to the camera, the beam including a plurality of links connected together for relative rotation between adjacent links, the links structured such that, when adjacent links are in a straight linear configuration, the adjacent links may rotate relative to each other in a first direction and cannot substantially rotate relative to each other in a second direction opposite the first direction;a guide sheath slidably receiving the beam, the beam extending through a distal end of the guide sheath such that the camera projects from the distal end of the guide sheath, the guide sheath including a first sheath portion defining a first axis and a second sheath portion defining a second axis, the guide sheath having an operative configuration wherein the first sheath portion is angled relative to the second sheath portion to define a first bend; andthe beam oriented relative to the guide sheath such that, as the beam is slid relative to guide sheath, the beam bends in the ...

THERMAL TRANSFER DEVICES, TEMPERATURE STABILIZED CONTAINERS INCLUDING THE SAME, AND RELATED METHODS

Generally, this disclosure relates to a temperature-stabilized and/or temperature-controlled storage container. In an embodiment, the storage container may include e a temperature-control regulator or assembly that may control the temperature in the interior space of the temperature-stabilized storage container. 1. A thermal transfer device for a storage container , the thermal transfer device comprising: a top plate;', 'a first pillar extending from the top plate; and', 'a second pillar extending from the top plate;, 'a housing including,'}at least one phase change material (PCM) container containing at least one first PCM and being configured to be positioned in thermal communication with the first pillar of the housing;at least one PCM carrier containing at least one second PCM and being configured to be positioned in thermal communication with one or more of the first pillar or the second pillar; anda heat pipe having a first thermal end thereof in thermal communication with one or more of the top plate, the first pillar, or the second pillar.2. The thermal transfer device of claim 1 , further including a base plate spaced from the top plate and from which the first and second pillars extend.3. The thermal transfer device of claim 2 , wherein the base plate is attached to the first and second pillars and positioned generally opposite to the top plate.4. The thermal transfer device of claim 1 , wherein the second pillar includes a first pillar portion and a second pillar portion connected together.5. The thermal transfer device of claim 4 , wherein the heat pipe is positioned between and secured in thermal communication to the first and second pillar portions.6. The thermal transfer device of claim 1 , wherein the heat pipe includes a second thermal end in thermal communication with one or more of a cooling unit or a heating unit.7. The thermal transfer device of claim 6 , wherein the second thermal end of the heat pipe is in thermal communication with a ...

Refrigeration devices including temperature-controlled container systems

In some embodiments, a refrigeration device includes: walls substantially forming a liquid-impermeable container configured to hold phase change material internal to a refrigeration device; at least one active refrigeration unit including a set of evaporator coils positioned within an interior of the liquid-impermeable container; walls substantially forming a storage region; and a heat transfer system including a first group of vapor-impermeable structures with a hollow interior connected to form a condenser in thermal contact with the walls substantially forming a liquid-impermeable container, a second group of vapor-impermeable structures with a hollow interior connected to form an evaporator in thermal contact with the walls substantially forming a storage region, and a connector with a hollow interior affixed to both the condenser and the evaporator, the connector forming a liquid and vapor flow path between the hollow interior of the condenser and the hollow interior of the evaporator.

PORT ACCESS VISUALIZATION PLATFORM

A medical system generally comprises a camera head, a beam, and a guide sheath. The camera head is connected to the beam which is bendable in a first direction and resists bending in a second direction opposite the first direction. The guide sheath slidably receives the beam, the beam extending through a distal end of the guide sheath such that the camera head projects from the distal end of the guide sheath. The guide sheath includes first and second sheath portions, and in an operative configuration the first sheath portion is angled relative to the second sheath portion to define a first bend. The beam is oriented relative to the guide sheath such that, as the beam is slid relative to guide sheath, the beam bends in the first direction through the first bend, and a projecting portion of the beam resists bending in the second direction. 1. A medical system for use intracorporeally to assist in surgical procedures beneath a tissue layer , the system comprising:a camera;a beam having a distal end attached to the camera, the beam bendable in a first direction and resisting bending in a second direction opposite the first direction;a guide sheath slidably receiving the beam, the beam extending through a distal end of the guide sheath such that the camera projects from the distal end of the guide sheath, the guide sheath including a first sheath portion defining a first axis and a second sheath portion defining a second axis, the guide sheath having an operative configuration wherein the first sheath portion is angled relative to the second sheath portion to define a first bend; andthe beam oriented relative to the guide sheath such that, as the beam is slid relative to guide sheath, the beam bends in the first direction through the first bend, and a projecting portion of the beam projecting from the distal end of the guide sheath resists bending in the second direction.2. The medical system of claim 1 , wherein the beam sufficiently resists bending such that it does ...

SYSTEMS AND METHODS FOR INSECT DISSECTION

The present disclosure relates to devices, systems, and methods that may be used to dissect insects. In some embodiments, the systems, devices, and methods may be used to isolate insect salivary glands. In some embodiments, the systems, devices, and methods may be used to isolate mosquito salivary glands. In some embodiments, the systems, devices, and methods may be used to collect mosquito salivary glands. 1. A device comprising:one or more first members having one or more thorax orifices through which a head portion of an insect can protrude and which restrains a thorax portion of the insect; andone or more second members having one or more head orifices that can accept the head portion of the insect and that are operably coupled to the one or more first members so that lateral movement of the one or more first members relative to the one or more second members substantially immobilizes the head portion of the insect.2. The device of claim 1 , wherein the one or more first members having one or more thorax orifices through which a head portion of an insect can protrude and which restrains a thorax portion of the insect comprises:one or more first members having one or more thorax orifices through which the head portion of a mosquito can protrude.314-. (canceled)15. The device of claim 1 , wherein the one or more first members having one or more thorax orifices through which a head portion of an insect can protrude and which restrains a thorax portion of the insect comprises:one or more first members that include one or more substantially planar thorax plates having one or more thorax orifices through which the head portion of the insect can protrude.1622-. (canceled)23. The device of claim 1 , wherein the one or more second members having one or more head orifices that can accept the head portion of the insect and that are operably coupled to the one or more first members so that lateral movement of the one or more first members relative to the one or more second ...

Temperature-Stabilized Storage Systems with Integral Regulated Cooling

In some embodiments, a regulated thermal transfer device for a storage container includes: a phase change material unit, the phase change material unit including one or more walls surrounding a phase-change material region, and an aperture in the one or more walls; a heat pipe with a first end positioned within the phase change material unit, and a second end; a thermoelectric unit thermally connected to the second end of the heat pipe; a heat sink connected to the thermoelectric unit, and positioned to radiate heat away from the thermoelectric unit; and an electronic controller operably connected to the thermoelectric unit; wherein the regulated thermal transfer device is of a size and shape to be positioned so that the phase change material unit is within a storage region of a temperature-stabilized storage container, and the thermoelectric unit is positioned adjacent to an external surface of the temperature-stabilized storage container. 1. A regulated thermal transfer device for a storage container , comprising:a phase change material unit, the phase change material unit including one or more walls surrounding a phase-change material region, and an aperture in the one or more walls;a heat pipe with a first end positioned within the phase change material unit, and a second end traversing the aperture of the one or more walls of the phase change material unit;a thermoelectric unit thermally connected to the second end of the heat pipe;a heat sink connected to the thermoelectric unit, and positioned to radiate heat away from the thermoelectric unit; andan electronic controller operably connected to the thermoelectric unit;wherein the regulated thermal transfer device is of a size and shape to be positioned so that the phase change material unit is within a storage region of a temperature-stabilized storage container, and the thermoelectric unit is positioned adjacent to an external surface of the temperature-stabilized storage container.2. (canceled)3. The ...

Methods and systems to alter the permeability of a biological object

The present disclosure relates to methods and systems that may be used to alter the permeability of a biological object. In some embodiments, the methods and systems may be used to alter the permeability of a non-human embryo. In some embodiments, the methods and systems may be used to alter the permeability of an insect embryo. In some embodiments, the methods and systems may be used to alter the permeability of a mosquito embryo.

DEVICES, METHODS, AND SYSTEMS FOR COLLECTION OF INSECT SALIVARY GLANDS

The present disclosure relates to devices, methods and systems that may be used to collect insect salivary glands. In some embodiments, the devices, methods, and systems may be used to collect salivary glands from a mosquito. 1. A device comprising:two or more fluid reservoirs that are operably coupled to allow fluid flow between the two or more fluid reservoirs through one or more hydrodynamic shear members;two or more fluid displacement members that are each individually moveably coupled within each of the two or more fluid reservoirs;one or more drive mechanisms that are operably coupled to each of the two or more fluid displacement members and configured to move each of the two or more operably coupled fluid displacement members in coordinated opposition to each other within each of the two or more fluid reservoirs; andone or more control units that are configured to control operation of the one or more drive mechanisms.2. (canceled)3. The device of claim 1 , wherein the two or more fluid reservoirs that are operably coupled to allow fluid flow between the two or more fluid reservoirs through one or more hydrodynamic shear members comprise:two or more fluid reservoirs that are operably coupled through one or more hydrodynamic shear members that are constriction couplings.4. The device of claim 1 , wherein the two or more fluid reservoirs that are operably coupled to allow fluid flow between the two or more fluid reservoirs through one or more hydrodynamic shear members comprise:two or more fluid reservoirs that are operably coupled through one or more hydrodynamic shear members that are cavitation devices.57-. (canceled)8. The device of claim 1 , wherein the one or more drive mechanisms that are operably coupled to each of the two or more fluid displacement members and configured to move each of the two or more operably coupled fluid displacement members in coordinated opposition to each other within each of the two or more fluid reservoirs comprise:at least one ...

REFRIGERATION DEVICES INCLUDING TEMPERATURE-CONTROLLED CONTAINER SYSTEMS

In some embodiments, a refrigeration device includes: walls substantially forming a liquid-impermeable container configured to hold phase change material internal to a refrigeration device; at least one active refrigeration unit including a set of evaporator coils positioned within an interior of the liquid-impermeable container; walls substantially forming a storage region; and a heat transfer system including a first group of vapor-impermeable structures with a hollow interior connected to form a condenser in thermal contact with the walls substantially forming a liquid-impermeable container, a second group of vapor-impermeable structures with a hollow interior connected to form an evaporator in thermal contact with the walls substantially forming a storage region, and a connector with a hollow interior affixed to both the condenser and the evaporator, the connector forming a liquid and vapor flow path between the hollow interior of the condenser and the hollow interior of the evaporator. 1. A refrigeration device , comprising:one or more walls substantially forming a liquid-impermeable container, the liquid-impermeable container configured to hold phase change material internal to a refrigeration device;at least one active refrigeration unit including a set of evaporator coils, the evaporator coils positioned within an interior of the liquid-impermeable container;one or more walls substantially forming a storage region; anda heat transfer system including a first group of vapor-impermeable structures with a hollow interior connected to form a condenser in thermal contact with the one or more walls substantially forming a liquid-impermeable container, a second group of vapor-impermeable structures with a hollow interior connected to form an evaporator in thermal contact with the one or more walls substantially forming a storage region, and a connector with a hollow interior affixed to both the condenser and the evaporator, the connector forming a liquid and vapor ...

Refrigeration devices including temperature-controlled container systems

In some embodiments, a refrigeration device includes: walls substantially forming a liquid-impermeable container configured to hold phase change material internal to a refrigeration device; at least one active refrigeration unit including a set of evaporator coils positioned within an interior of the liquid-impermeable container; walls substantially forming a storage region; and a heat transfer system including a first group of vapor-impermeable structures with a hollow interior connected to form a condenser in thermal contact with the walls substantially forming a liquid-impermeable container, a second group of vapor-impermeable structures with a hollow interior connected to form an evaporator in thermal contact with the walls substantially forming a storage region, and a connector with a hollow interior affixed to both the condenser and the evaporator, the connector forming a liquid and vapor flow path between the hollow interior of the condenser and the hollow interior of the evaporator.

Refrigeration devices including temperature-controlled container systems