18-04-2019 дата публикации
Номер: US20190111131A1
Автор:
Seonyoung NAM,
Kwang Hee YANG,
Su-Jae LEE,
Rae-Kwon KIM,
NAM SEONYOUNG,
YANG KWANG HEE,
LEE SU-JAE,
KIM RAE-KWON,
NAM, Seonyoung,
YANG, Kwang Hee,
LEE, Su-Jae,
KIM, Rae-Kwon
Принадлежит:
The present invention relates to an apparatus for inhibiting oncogene-induced malignant carcinogenesis, including an irradiation unit for applying low-dose radiation to a subject, and to a method of inhibiting oncogene-induced malignant carcinogenesis, including applying low-dose radiation to a subject, whereby oncogene-induced malignant carcinogenesis can be inhibited by means of the apparatus and method of the present invention. 1. An apparatus for inhibiting oncogene-induced malignant carcinogenesis , comprising an irradiation unit for applying low-dose radiation to a subject.2. The apparatus of claim 1 , wherein the low-dose radiation has a cumulative dose of 100 mGy or less but exceeding 0 mGy.3. The apparatus of claim 1 , wherein the oncogene is K-Ras.4. The apparatus of claim 1 , wherein the radiation is at least one selected from the group consisting of alpha rays claim 1 , beta rays claim 1 , gamma rays claim 1 , electron rays claim 1 , UV rays claim 1 , and X-rays.5. A method of inhibiting oncogene-induced malignant carcinogenesis claim 1 , comprising applying low-dose radiation to a subject.6. The method of claim 5 , wherein the subject is a mammal other than a human.7. The method of claim 5 , wherein the low-dose radiation has a cumulative dose of 100 mGy or less but exceeding 0 mGy.8. The method of claim 5 , wherein the oncogene is K-Ras.9. The method of claim 5 , wherein the radiation is at least one selected from the group consisting of alpha rays claim 5 , beta rays claim 5 , gamma rays claim 5 , electron rays claim 5 , UV rays claim 5 , and X-rays. The present invention relates to an apparatus for inhibiting oncogene-induced malignant carcinogenesis, comprising an irradiation unit for applying low-dose radiation to a subject, and to a method of inhibiting oncogene-induced malignant carcinogenesis, comprising applying low-dose radiation to a subject.Although definitive effects and carcinogenesis due to high-dose radiation exposure are well known, the ...
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