INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS

A novel therapeutic drug for malignant tumors, cancer stem cells, or fibrosis is obtained. A therapeutic drug for malignant tumors or cancer stem cells is used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof. Alternatively, a therapeutic drug for fibrosis can be used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof.

INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS

A novel therapeutic drug for malignant tumors, cancer stem cells, or fibrosis is obtained. A therapeutic drug for malignant tumors or cancer stem cells is used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof. Alternatively, a therapeutic drug for fibrosis can be used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof. 2. The method of treating a malignant tumor according to claim 1 , wherein the R claim 1 , R claim 1 , R claim 1 , R claim 1 , and Rare the same or different and each represent H claim 1 , halogen claim 1 , nitro claim 1 , cyano claim 1 , OH claim 1 , Calkyl claim 1 , Chalogenoalkyl claim 1 , Chydroxyalkyl claim 1 , Calkylamino claim 1 , 01-6 alkoxy claim 1 , 01-6 halogenoalkoxy claim 1 , Chydroxyalkoxy claim 1 , or Calkoxyamino claim 1 , or Calkoxy-substituted Calkoxy claim 1 , Calkoxyphenyl-substituted Calkoxy claim 1 , (trialkylsiloxy) Calkyl claim 1 , or (alkyl diphenyl siloxy) Calkyl;{'sup': 3', '7, 'the Rand Rare H;'}the ring A is naphthyl, phenyl substituted by five halogens, or furyl substituted by one methyl; and{'sup': 8', '9, 'sub': '1-6', 'the Rand Rare the same or different and each represent Calkyl.'}5. The method of treating a cancer stem cell according to claim 4 , wherein the R claim 4 , R claim 4 , R claim 4 , R claim 4 , and Rare the same or different and each represent H claim 4 , halogen claim 4 , nitro claim 4 , cyano claim 4 , OH claim 4 , Calkyl claim 4 , Chalogenoalkyl claim 4 , Chydroxyalkyl claim 4 , Calkylamino claim 4 , Calkoxy claim 4 , Chalogenoalkoxy claim 4 , Chydroxyalkoxy claim 4 , or Calkoxyamino claim 4 , or Calkoxy-substituted Calkoxy claim 4 , Calkoxyphenyl-substituted Calkoxy claim 4 , (trialkylsiloxy) Calkyl claim 4 , or (alkyl diphenyl siloxy) Calkyl;{'sup': 3', '7, 'the Rand Rare H;'} ...

Inhibitory effect of low molecular weight compound on cancer and fibrosis