排液系统
Technical Field The invention relates to a liquid drainage system, the system is used to add the completion of the container, liquid pumping, liquid discharge, and a predetermined separation, and the like required in the course of processing. Background Art In clinical chemical, biochemical, pharmaceutical chemistry in the field of chemical analysis, the reaction process to be completed in a variety of processing, such as the addition of the reagent, the liquid suction, discharge and separation, and the like. For example, in micro-plate assembly or small bottles and the like in the liquid sample in the container under the condition of containing the target substance, is added to the liquid sample for the target material holding in their respective on the surface of the magnetic particle. The target substance after on the surface of the magnetic particle, the supernatant by aspiration and discharges , the target substance can be separated with the liquid sample. In this processing, only the supernatant by aspiration and discharge of the exhausting of the magnetic particles containing the target substance. To this end, the magnet is close to the container in order to collect the magnetic particles in a location. Such as the use of magnetic particle separation processing traditional processing is accomplished by manual operation or by the suction of the plunger is provided with a plurality of the mechanism. Traditional such as manual separation of the operation of the trouble processing needs, such as the operation of the magnet is close to the container and through the liquid discharge pipe, and the like the operation of the supernatant. In arrangement many the miniature board, small bottles and the like for processing small containers under the condition of, processing need to spend a very long time. On the other hand, in order to through the plunger and actuate a plurality of micro-pipette, the multi-plunger pumping mechanism is used for automatic separation system requires a high-precision control for the actuating mechanism of each piston. Therefore, the system is complicated in structure and expensive. Purpose of the invention The purpose of this invention is to provide a drainage system, the system can utilize the simple mechanism to complete the suction, discharge, separation processing. To achieve the above object, according to the 1st aspect of the present invention to provide a drainage system, the system includes a suction and discharge from the container of the solution in the nozzle; for supporting for suction nozzle and of the suction nozzle towards the container movement of the supporting device of the mobile device; and suction nozzle mobile device, the mobile device comprises the suction nozzle is used for pushing the suction nozzle towards the device to move the container, supported by the support device at the same time, the mobile device can body of the suction nozzle position and make the suction nozzle at the end of the contact surface of the inner wall of the same container. According to the 1st aspect of the invention, support device make the suction nozzle close to the container in order to contact the end of the suction nozzle and the inner wall surface of the bottom of the container. The suction nozzle towards the container driving device, the support device supports mobile a suction nozzle. If the suction nozzle contact on the bottom of the container after the surface of the inner wall of supporting device further towards the container moves, then the suction nozzle can be maintained at the bottom of the end part of the inner wall surface of the contact. Such circumstances, the suction nozzle from inside the container suction and discharge the solution. After the solution is the suction and discharge of the suction nozzle is separated from the container, towards the container by the pushing device for pushing the suction nozzle can be naturally return to its initial position. Therefore, the mobile device using a suction nozzle suction nozzle can be positioned at the bottom of the container and does not need to carry out the positioning control suction nozzle. Furthermore, through the suction nozzle is positioned in the bottom of the container can reduce the residual quantity of the solution. According to the present invention, by using a suction pump through the plurality of suction nozzle by the suction of the solution can be the suction nozzle with a plurality of the manifold connections. Furthermore, the liquid delivery device through the liquid filled with the multi-manifold and each of the tube between the suction nozzle, the solution in the container can be sucked from the suction nozzle and at the same time its discharge and will not produce the suction of only aspirates the air, even if any part of the container is empty. Examples of the discharge device according to the solution, between the suction pump and a manifold ensuring that there is the proper capacity and resistance, in addition, between the manifold and the suction pipe also ensure that there is the proper capacity. If the suction nozzle and each of the multiple manifold capacity ratio of the space between the large capacity of the container, then, all of the solution in the container is sucked out in a multi-manifold before a negative pressure can be ensured, it is possible to maintain the stable pumping. Furthermore, with the multi-manifold through the nozzle to ensure that the appropriate resistance between appropriate pumping speed can be obtained. Furthermore, between the multi-manifold and the suction pump the capacity of the suction pump can be absorbed at the time of starting or stopping the operation of the abrupt pressure change caused by the, suction by the suction nozzle slow down the start and stop of the magnetic particle can be prevented from being discharged from the container. The multi-manifold and a suction pump also to ensure that appropriate between the resistance of the appropriate pumping speed can be obtained. In order to ensure that between the multi-manifold and the suction pump of suitable capacity, can be in a multi-manifold and the suction pump is connected between the pipe or with suitable capacity of the buffer tank. According to the 3rd aspect of the present invention to provide a drainage system, the system includes the above-mentioned all of the device, the device comprising a suction nozzle mobile device, magnetic particles hold the device, and a solution discharge device. Description of drawings In the joint in the Figure in the description of the preferred embodiment can be more clearly understanding the invention the above and other purposes and characteristics. Figure 1 is the outline diagram of the structure of discharge system of this invention; Figure 2 is the flow chart of Figure 1 indicated by the discharge system; Figure 3A to Figure 3D is the working diagram of the suction nozzle described Figure 1 indicated by the discharge system; Figure 4A to Figure 4D is running and the chart of Figure 1 the magnetic particle discharge system shown in the receiving device; Figure 5A to Figure 5C is running and the chart of Figure 1 the suction nozzle discharge system shown in the example of the mobile device; Figure 6A to Figure 6C is running and the chart of Figure 1 shown in a discharge system and the other suction nozzle of an example mobile device; Figure 7 is an enlarged view of the structure of Figure 1 is shown the end of the suction nozzle of the liquid-discharging system; Figure 8A and 8B to Figure 1 of the discharge system shown in a deformation of the suction nozzle. Mode of execution The following reference Figure 1 liquid discharging system of the present invention is outlined. Discharge system 1 includes a plurality of suction nozzle 2, the suction nozzle mobile device 3, magnetic particles hold the device 4, and a solution discharge device 5. Mobile device 3 the suction nozzle 2 moves toward or away from the container, such as the miniature board assembly 6. Holding device 4 the magnetic particle retention in the container 6 in, thereby preventing the suction nozzle of the magnetic particle 2 is sucked out. Discharge device 5 make the suction nozzle 2 to suck out the solution container 6 placed into the container side by side 5f inner. Container 6 is not limited to the miniature board assembly, it may be any other small bottles and the like of the container can hold a liquid sample. Will be used to keep the target substance is put into the container of the magnetic particles 6. In the following description of the embodiment of the invention, container 6 adopts the miniature board assembly. The suction nozzle 2 of the single to the end of the micro-plate assembly is inserted into the-slot 6a in, the, such as suction or discharge liquid sample solution. The suction nozzle mobile device 3 can be easily the suction nozzle 2 moves toward or away from the miniature board assembly 6 and the suction nozzle 2 positioned in the-slot 6a in. The suction nozzle mobile device 3 comprises means for the support of the suction nozzle 2 moves toward or away from the miniature board assembly 6 of the support device and is used for pushing the suction nozzle 2 toward the miniature board assembly 6 of the pushing device. Supporting device the suction nozzle 2 toward the miniature board assembly 6. Furthermore, the end part of the suction nozzle with the-slot 6a after the contact, the pushing device the suction nozzle 2 each end of the single positioning in the miniature board assembly 6 of the-slot 6a on the specific position of the and need not control the position of the supporting device. Magnetic particle receiving device 4 utilizes the magnetic collection of micro-plate assembly 6 of the-slot 6a of the magnetic particles and prevent them from the same solution to the suction nozzle 2 is sucked out. Receiving device 4 includes the magnet 8, and a moving mechanism, magnet 8 with the micro-plate assembly 6 is the bottom side of, the magnet moving mechanism is capable of 8 toward the and removing the miniature board assembly 6. Solution discharge device 5 through the suction nozzle 2 at the same time suction and discharge the miniature board assembly 6 of the solution. Discharge device 5 includes a plurality of manifold having branched end 5b, and each of the branched end 2 of the single is connected with the tube 5a, is used for the multi-manifold from the suction nozzle 2 to the suction pump solution of 5c, and the liquid is supplied to the pipe 5a in order to use the liquid filled with them the liquid conveying device (switch valve 5d, a delivery pump 5e, the cleaning liquid container 5f, the cleaning liquid 5g, and the like). The solution discharge device 5 of the multi-manifold 5b with the suction nozzle 2 connected, so the liquid can be a single suction pump 5c suction. Furthermore, extending the multi-manifold 5b and a suction nozzle 2 the tube between the 5a is filled with liquid for the liquid delivery device. If the micro-plate assembly 6 any one of the-slot 6a is empty, -slot 6a can be automatically of the solution in the through the suction nozzle 2 at the same time is sucked and discharged and will not produce the suction of only air is sucked out. For example, if the multi-manifold 5b located in branched end with the suction nozzle 2 is connected with the tube 5a is arranged the ratio of the capacity of the miniature board assembly 6 with large capacity, multi-manifold 5b to the suction pump 5c the part of the negative pressure can be maintained between, then the miniature board assembly 6 in the whole of the solution is sucked out stably. Furthermore, through making the pipe 5a has an appropriate resistance of the suction speed can be appropriately adjusted. When the switch valve 5d and a suction pump 5c a can be provided between the buffer tank 5h as adjusting from the multi-manifold into the suction side portion of capacity and resistance. Buffer tank 5h has a specific capacity and resistance, therefore, if the suction pump operation generated when the start or stop of any sudden pressure changes it is easy to make the suction nozzle 2 of the soft suction operation. If, in the miniature board assembly 6 is completely sucked out of the solution within before pump stops running, in particular, even if it is after the operation of the go on the buffer tank 5 to the negative pressure in the solution is sucked out under the action of, the micro-plate assembly may be 6 evacuation. When such operations, and between the negative pressure at any time, then the suction can slowly end. Therefore, suction of the magnetic particle can be prevented. By the arrangement of the multi-manifold 5b and the suction pump 5c can also replace the tube between the buffer tank 5h to regulate the capacity and resistance. The following reference flowdiagram 2 apocenosis the operation of the system to carry out general description. First of all, in step S1 to step S3 in the process of, the liquid pipe 5a is filled with. To do so even the miniature board assembly 6 is empty of any-slot of the suction does not occur at the same time also can realize the suction nozzle 2 suction. The suction nozzle mobile device 3 the suction nozzle 2 is moved to the the micro-plate assembly 6 the position of the certain distance (step S1). Furthermore, conversion switch valve 5d so that a plurality of manifold 5b the same delivery pump 5e (step S2) is connected. Delivery pump 5e from the cleaning liquid container 5f is sucked out in clean liquid 5g, the manifold 5b to the suction nozzle 2 the tube between the 5a is clean liquid 5g is filled with (step S3). In the step S3 in the process of, the suction nozzle 2a and 2b and pipe 5a from the hollow state (Figure 3A) conversion to the filled with the state of the liquid (Figure 3B). Therefore, as shown in Figure 3B shown, through the suction nozzle 2a and 2b and the tube 5a is filled with the liquid, even the miniature board assembly 6 a-slot in 6a is empty, the tube 5a of the liquid can be sucked out, as shown in Figure 3C illustrated. Therefore, sucking out air only can be prevented from occurring without suction to the liquid condition. The liquid pipe 5a is filled with operation can also be used for purifying the suction nozzle. Figure 3D-slot in the case of the shown in 6a, the liquid is sucked out of the suction nozzle 2a and 2b and the tube 5a is empty, such a situation, if one of the-slot 6a is empty, then the air is sucked out through it. If a high pumping speed of the pump is not, then the other-slot 6a of the liquid cannot be sucked in. Perhaps this speed is too high so as to not be able to prevent the magnetic particles is sucked out together with the liquid. Furthermore, magnetic particles hold the device 4 to make the magnet 8 is moved toward the miniature board assembly 6 of the bottom side (step S4), then the magnet 8 on the magnetic particle retention in the miniature board assembly 6 each-slot 6a on the surface of the inner wall of (step S5). The following reference picture 4A to 4D pair of magnetic particle receiving device 4 to describe an example of the. Figure 4A to 4B are magnetic particle receiving device 4 a side view and an elevational view of, wherein, the magnets 8 away from the miniature board assembly 6. 4C to 4D are magnetic particle receiving device 4 a side view and an elevational view of, wherein, the magnets 8 close to the miniature plate assembly 6. Magnetic particle receiving device 4 comprises a 1st supporting plate 4a and 2nd support plate 4e. 1st supporting plate 4a with the magnet 8 fit. When the base plate 4g of the eccentric cam 4i rotating, 2nd support plate 4e in the 4g is arranged on a plurality of supporting column 4f under the guidance of the (in the vertical direction) toward and away from base plate 4 g. 2nd support plate 4e located in support plate 1st 4a the underface, and the spring 4c is placed in the 1st supporting plate 4a and the 2nd support plate 4e between. If the 2nd support plate 4e with the eccentric cam 4i rotate and rise, then the motion through a spring 4c is transmitted to the 1st supporting plate 4a and the supporting plate 1st 4a rises. Cam 4I is fixed on the base plate by the 4g motor on 4h drive. Cam 4i the rotation of the bearing 4j and support 4k raise or lower supporting plate 2nd 4e. Shaft 4b is fixed on the one end of the supporting plate 1st 4a the upper. Furthermore, support plate 2nd 4e is equipped with a shaft retainer 4d it can hold shaft 4b for sliding the end of the. Spring 4c is mounted on the shaft in the 4b upper. Therefore, the support plate 1st 4a is composed of a spring 4c support plate supported on the 2nd 4e above. Furthermore, shaft 4b and the shaft retainer 4d can also be are respectively fixed on the 2nd and 1st supporting plate 4e and 4a the upper. When the eccentric cam 4I rotation 2nd support plate 4e is moved to its lower position, the support plate 1st 4a also moves to its lower position, that is, leaving the miniature board assembly 6 the position of the bottom surface of. On the other hand, if the eccentric cam 4I further rotate so that the 2nd support plate 4e vaknin, then the support plate 1st 4a also through the spring 4c vaknin and is located near to the micro-plate assembly 6 the position of the bottom surface of. This case, the magnet 8 is located at respectively the miniature board assembly 6 the groove on the bottom surface 6d the inner. Therefore, -slot 6a on the magnetic particles by the magnet 8 to attract and collect. Figure 5A to fig. 5C magnetic particle is shown collected in one of the-slot 6a bottom 6b the situation on the surface of the inner wall. If the supporting plate of the 1st and 2nd 4a and 4e to the support to adjust the distance between plate 4a with the micro-plate assembly 6 the bottom of 6c the support plate after contacting 2nd 4e further rise, then spring 4c shrink in order to absorb the 2nd support plate 4e the rising (Figure 4C and 4D). Therefore, due to the spring 4c is contracted and does not control 2nd support plate 4e or similar, then the position of each magnet 8 can be in the bottom 6c on the miniature board assembly 6 corresponding groove 6d inner. Furthermore, the suction nozzle mobile device 3 the suction nozzle 2 toward the miniature board assembly 5 (step S6). Figure 5A to fig. 5C and 6A to fig. 6C suction nozzle gives the mobile device 3 to the two examples. In Figure 5A to fig. 5C shown in the mobile device for the suction nozzle 3A in, the suction nozzle 2 by the guide part 3c is slidably supported and through the collar 3b is composed of a spring 3a towards the micro-plate assembly 6 to promote. In Figure 6A to fig. 6C shown in the mobile device for the suction nozzle 3B in, the suction nozzle 2 by the guide part 3c is slidably supported and through the collar 3b by weight 3d towards the micro-plate assembly 6 to promote. In the following described embodiments, the chart 5A to fig. 5C shown in the mobile device for the suction nozzle 3 as Figure 1 the suction nozzle shown in the mobile device. Mobile device the nozzle toward the miniature board assembly 6 time, the suction nozzle 2 end 2A close to and its corresponding the miniature board assembly 6 of the-slot 6a and adjacent the-slot 6a at the bottom of the of 6b (step S7). If the suction nozzle mobile device 3 further toward the miniature board assembly 6, the spring 3a absorbs the additional mobile, then the suction nozzle 2 end 2A could be maintained and the bottom 6b of the contact. By this suction nozzle 2 with respect to the the miniature board 6 easily positioning and does not require the mobile device to the suction nozzle 3 to conduct any special position control. Furthermore, conversion switch valve 5 of the multi-manifold 5b and the suction pump 5c or buffer tank 5h (step S8) is turned on, the suction pump 5c solution from the miniature board assembly 6 of the-slot 6a sucked in (step S9). In the suction process, pre-injected pipe 5a is sucked out of the first cleaning liquid, at the same time-slot 6a is into the solution in the pipe 5a in. Furthermore, in the suction process, magnetic particles 7 by the magnet 8 to collect and maintain, and because the pipe 5a is filled with the liquid, it is possible to suck out at a low pumping speed solution. By this magnetic particles 7 will not be suction nozzle 2 of the suction discharge. If the micro-plate assembly 6 than the capacity of the pipe 5a in order to with a large capacity in the suction process the pipe 5a through the other suction nozzle and in the efficiency of the suction is reduced, then can increase the efficiency of suction of the ascending step S1 to step S3 is repeated through the liquid in the pipe 5a is filled with to achieve. After the end of the suction, the mobile device through the suction nozzle 3 will each suction nozzle 2 with the miniature board assembly 6 separation (step S10). In this way the suction nozzle 2 can be by a spring 3a through the return and the thrust of the collar 3b, is located at its initial position. Conversion switch valve 5d of the multi-manifold 5b the same delivery pump 5e (step S11) is connected, and through the pump 5e the cleaning liquid container 5f cleaning liquid in the 5g injection pipe 5a and a suction nozzle 2, by the cleaning pipe 5a and a suction nozzle 2 (step S12). Figure 7 as shown in Figure 1 shown in the suction nozzle 2 an example of the, wherein the suction nozzle 2 at the end of the with an inclined 2A. The suction nozzle 2 end 2A slope can prevent the end 2A closing the opening of the, even end 2A contact to its corresponding-slot 6a at the bottom of the of. Figure 8A and 8B plurality of suction nozzles shown 2, the suction nozzle moving device 3 is connected with them respectively. If the suction nozzle 2 each of the miniature board assembly relative to the end of the 6 (height) the position of the are not equal, then according to such an arrangement, the suction nozzle mobile device 3 of the support device and the propelling device can make the suction nozzle with satisfaction with the end of the-slot 6a is in contact with and does not need any special position control. If Figure 1, the pump 5e is a constant delivery pump, then through the suction nozzle 2 can in fixed injection rate of the reagent. Even in Figure 8A shown in the manner of arranging a plurality of the suction nozzle 2, by respectively adjusting multi-manifold 5b and the tube 5a also to the resistance of the desired rate of dispensing reagent. According to an embodiment of the invention, the mobile device using a suction nozzle, magnetic particles hold the device, solution discharge device, or their engagement can easily realize suction and discharge and does not need to carry out special control of the positioning. Furthermore, solution can through the plurality of suction nozzle at the same time suction and discharge, at the same time, also capable of cleaning these suction nozzle. As mentioned above, discharge system according to the present invention, suction, discharge and separation, and the like can be the process is completed by use of a simple mechanism. In a system for sucking and discharging a solution from a vessel (micro-plate assembly 6 ) by suction nozzles 2 , processes for suction, discharge, separation, etc. can be carried out with use of a simple mechanism, including suction nozzle moving means 3 for positioning the respective distal ends of the suction nozzles on the inner wall surface of the vessel, magnetic particle holding means 4 for magnetic particles 7 in a given position in the vessel, and solution discharge means 5 for sucking out and discharging the solution simultaneously from the vessel through the suction nozzles. Each or a combination of these means constitutes a drainage system. 1. A liquid drainage system, the system comprises: From the container for suction and discharge of the solution in the nozzle; Used for supporting for suction nozzle and of the suction nozzle towards the container movement of the supporting device of the mobile device; and Mobile device a suction nozzle, the suction nozzle is used for pushing the mobile device comprises the suction nozzle towards the device to move the container, supported by the support device at the same time, The mobile device can body of the suction nozzle position and make the suction nozzle at the end of the contact surface of the inner wall of the same container. 2. A liquid drainage system, the system comprises: From the container for suction and discharge of the plurality of suction nozzle of the solution; Is used for supporting the suction nozzle towards the container of moving the supporting device; Mobile device a suction nozzle, the suction nozzle is used for pushing the mobile device comprises the suction nozzle towards the container to move the device, and is used for the suction nozzle positioning and make the suction nozzle at the end of the contact surface of the inner wall of the same container; Magnet; Magnet mobile device, the magnet mobile device used for supporting a magnet so that the magnet can move toward and removes the container, and when the mobile device by the magnet the container when the container is moved toward the magnet to keep the magnetic particles on the specific position in the container, Connected with the suction nozzle through the tube of the manifold; Used for through its operation by the multi-manifold from the suction nozzle at the same time suction in suction pump the liquid in the container; and The liquid conveying device, the conveying device is used for the liquid is supplied to the multi-manifold with each of the suction nozzle in the tube between the by the liquid filled with the tube.