Soluble powder for treating mixed infection of livestock and poultry caused by bacteria and coccidian
Technical Field The invention belongs to the field of veterinary medicine, in particular to a used for the treatment of livestock and poultry mixed infection of bacteria and coccidium soluble powder. Background Art The expansion of the scale of the intensive cultivation, livestock and poultry various aspects of the disease becoming more and more serious. At the same time as the antibiotic drugs of abuse of the cultivation for in livestock and poultry, the problem of drug-resistant strain is also increasingly serious. Because the livestock and poultry bacteriosis of the collective and parasitic disease outbreak, often serious impact on the utilization rate of weight gain and feed for poultry and livestock, the poultry laying rate is reduced, the quality of the carcass downstaged, even a considerable number of deaths caused by, impact on the economic benefit of the other. Livestock and poultry bacterial disease in livestock and poultry production more complicated, there are many kinds of diseases, caused by a single bacteria, there are also bacteria caused by the infection of mixing and mycorplasma, morbidity and mortality ranged. The bafflingly poultry coccidiosis has also become a major issue mariculturists, often for the prevention and treatment of improper lead to secondary infection. Content of the invention Based on the above-mentioned situation, the purpose of this invention is to provide a kind of used for the treatment of livestock and poultry mixed infection of bacteria and coccidium soluble powder The purpose of this invention is realized as follows: are respectively expressed by weight percentage of the sulfuric acid colomycin 3.5%-4.5%, sulfadimidine sodium 2%-3%, male 0.03%-0.07%, auxiliary materials 92.43%-94.47%. The auxiliary materials comprise: anhydrous glucose, oral glucose, preferably glucose water-free. In order to get better result, preferably component is: sulfuric acid colomycin 4%, sulfadimidine sodium 2.5%, male 0.05%, auxiliary materials 93.45%. The invention can adopt a trade general process, device preparation. Preferably prepared by the following method, comprising the steps of: The sulfuric acid colomycin, sulfonamide diformic pyrimidine sodium and Diclazuril supplementary material to the crushing, pulverizing after 60 mesh sieve; heating sulfuric acid colomycin, sulfonamide diformic pyrimidine sodium and male of an equivalent amount of the auxiliary material with the same quantity of the cumulative dilution dilution, mixing, over 60 three times item of fine sizing , obtaining mixture; the mixture is mixed with the rest of the product, the mixture is over 80 item of fine sizing three times, get. Sulfuric acid colomycin: to narrow spectrum fungicide, to Escherichia coli, Salmonella, pasteurella, nutritive value, agreeable taste such as bacillus dysentery strong antibacterial action. Sterilization mechanism is damage bacteria cell membrane, increasing its permeability, the bacteria amino acid, purine, pyrimidine, leakage, also can influence karyoplasms and ribosome function, lead to bacterial death. Azolmetazin sodium: antibacterial effect is relatively sdz slightly weak, however, the inhibit function coccidium and antitoxoplasmosis a, the bad reaction is small, the livestock and maintain the effective concentration in the body for a longer time. Diclazuril: to triazine novel broad-spectrum anti-coccidium medicine, has the effect of killing coccidium, to the various phases of the development coccidium have a role, the role is at present the most strong a anticoccidiosis medicine. The medicine of the invention is an antibiotic medicine, used mainly caused by gram-negative bacteria and coccidium the diarrhea, homafecia, food dyspepsia, bowel syndrome. In order to verify the curing effect of the medicine of the present invention, the medicine takes this tianjin Jinghai county of a chicken farms do clinical trials. Heating persons with colibacillosis of chickens, at the same time also accompanied by diarrhea, the symptoms of blood, microscrope illness by chickens can be seen, the use of the drug of the present invention carry out the treatment, 1 g/l water, together 5 days is a course of treatment, a course of treatment of patients with most of the chicken is cured, the efficiency is up to 96% or more. Beneficial effects: it can be seen through the therapeutic effect experiment, the drug of the present invention for the treatment of livestock and poultry bacterial infection and coccidium indeed diseases, the invention formulation adopts azolmetazin sodium, sulfuric acid colomycin and Diclazuril the three kinds of medicament, for treating bacterial infections of the role at the same time, also can be used for the treatment of poultry coccidiosis secondary infection and control it. Good oral absorption, with relatively high security, is suitable for popularization and application in the production of animal husbandry. Mode of execution Embodiment 1: firstly, the sulfuric acid colomycin 35g, sulfadimidine sodium 20g, Diclazuril 3g and the supplementary product used water-free glucose 942g by crushing, pulverizing after 60 mesh sieve; heating Colistin sulfate, sodium azolmetazin of an equivalent amount of the auxiliary material with the same quantity of the cumulative dilution dilution, mixing, over 60 three times item of fine sizing , obtaining mixture; the mixture is mixed with the rest of the product, the mixture is over 80 item of fine sizing three times, to obtain the soluble powder approximately 1000g, wherein the sulfuric acid colomycin 35g, sulfadimidine sodium 20g, Diclazuril 3 g. Antibiotic medicine. Used mainly caused by gram-negative bacteria and coccidium the diarrhea, homafecia, food dyspepsia, bowel syndrome. Usage consumption: poultry: able to per liters pharmaceutical 1.2g or every thousand grams of medicament is able to feed in 2.4g; livestock: in the feed per thousand grams of adding the drug 1.2g, libitum, together 3-5 days is a course of treatment, the severe double quantity. Embodiment 2: firstly, the sulfuric acid colomycin 40g, sulfadimidine sodium 25g, Diclazuril 5g and the supplementary product used water-free glucose 930g by crushing, pulverizing after 60 mesh sieve; heating Colistin sulfate, sodium azolmetazin of an equivalent amount of the auxiliary material with the same quantity of the cumulative dilution dilution, mixing, over 60 three times item of fine sizing , obtaining mixture; the mixture is mixed with the rest of the product, the mixture is over 80 item of fine sizing three times, to obtain the soluble powder approximately 1000g, wherein the sulfuric acid colomycin 40g, sulfadimidine sodium 25g, male 5 g. Antibiotic medicine. Used mainly caused by gram-negative bacteria and coccidium the diarrhea, homafecia, food dyspepsia, bowel syndrome. Usage consumption: poultry: able to per liters pharmaceutical 1g or every thousand grams of medicament is able to feed in 2g; livestock: in the feed per thousand grams of adding the drug 1g, libitum, together 3-5 days is a course of treatment, the severe double quantity. Embodiment 3: firstly, the sulfuric acid colomycin 45g, sulfadimidine sodium 30g, Diclazuril 7g and the supplementary product used water-free glucose 975g by crushing, pulverizing after 60 mesh sieve; heating Colistin sulfate, sodium azolmetazin of an equivalent amount of the auxiliary material with the same quantity of the cumulative dilution dilution, mixing, over 60 three times item of fine sizing , obtaining mixture; the mixture is mixed with the rest of the product, the mixture is over 80 item of fine sizing three times, to obtain the soluble powder approximately 1000g, wherein the sulfuric acid colomycin 45g, sulfadimidine sodium 30g, Diclazuril 7 g. Antibiotic medicine. Used mainly caused by gram-negative bacteria and coccidium the diarrhea, homafecia, food dyspepsia, bowel syndrome. Usage consumption: poultry: able to per liters pharmaceutical 0.9g or every thousand grams of medicament is able to feed in 1.7g; livestock: in the feed per thousand grams of adding the drug 0.9g, libitum, together 3-5 days is a course of treatment, the severe double quantity. The present invention relates to a soluble powder which is used for treating mixed infection of domestic animal bacterium and coccidia, which comprises colistin sulfate, sulfadimidine sodium, dliclazuril and supplementary material. The medicine of the invention, which is taken as antibiotics medicine, is mainly used for intestinal syndromes of dysentery, hemafecia, food indigestion, etc., wherein the syndromes are caused by gram-negative bacterium and coccidian. The invention adopts three medicines of sulfadimidine sodium, colistin sulfate and dliclazuril for using together. When the soluble powder is acted on the sensitive bacteria infection, the soluble powder can also be used for treating coccidiosis of poultry. The soluble powder has the advantages of excellent oral absorption, higher safety, and suitability for the generalization and application in stock raising production. 1, a used for the treatment of livestock and poultry bacterial and coccidium soluble mixed infection of, the invention is characterized in that the medicament comprises a drug is: sulfuric acid colomycin, sulfadimidine sodium, male, supplementary product. 2, a used for the treatment of livestock and poultry bacterial and soluble powder mixed infection of coccidium according to Claim 1, characterized in that the percentage by weight of sulfuric acid colomycin 3.5%-4.5%, sulfadimidine sodium 2%-3%, male 0.03%-0.07%, auxiliary materials 92.43%-94.47%, the auxiliary materials comprise: anhydrous glucose, such as oral glucose, preferably glucose water-free. 3, a used for the treatment of livestock and poultry bacterial and soluble powder mixed infection of coccidium according to Claim 1, characterized in that preferably component is: sulfuric acid colomycin 4%, sulfadimidine sodium 2.5%, male 0.05%, auxiliary materials 93.45%.