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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 11307. Отображено 100.
05-07-2012 дата публикации

Nutritional formulations including human milk oligosaccharides and antioxidants and uses thereof

Номер: US20120172327A1
Принадлежит: ABBOTT LABORATORIES

Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

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11-04-2013 дата публикации

Agent for improving lipid metabolism

Номер: US20130089633A1
Принадлежит: Calpis Co Ltd

This invention provides an effective means or method for improving lipid metabolism, and a means or method for treatment or prevention of diseases or disorders associated with the lipid metabolism disorder. Specifically, this invention relates to an agent for improving the lipid metabolism comprising, as active ingredients, broken cells of a lactic acid bacterium, and to a method for enhancing an effect of a lactic acid bacterium for improving the lipid metabolism comprising a step of breaking the lactic acid bacterium.

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03-01-2019 дата публикации

METHOD FOR MANUFACTURING PROCESSED GINSENG CONTAINING HONEY COMPONENT

Номер: US20190000122A1
Автор: HO Seong Suk
Принадлежит:

Provided is a method for manufacturing processed ginseng containing a honey component. The method includes preparing a first mixture material containing ginseng and honey; steam-heating the first mixture material; cooling the first mixture material; separating the ginseng and the honey of the first mixture material; cooling the separated ginseng at a low temperature; cooling the separated honey at a room temperature; mixing the ginseng cooled at the low temperature and the honey cooled at the room temperature to form a second mixture material; aging the second mixture material at a low temperature; and acquiring ginseng from the second mixture material. According to the present invention, high-molecular ginsenoside is hydrolyzed by the honey component so that the contents of ginsenosideRg5+Rk1, Rg3, Rh2, and CompoundK, which may be easily absorbed by the body of a human being, increase. 1. A method for manufacturing processed ginseng containing a honey component , the method comprising:preparing a first mixture material containing ginseng and honey; steam-heating the first mixture material; cooling the first mixture material; separating the ginseng and the honey of the first mixture material; cooling the separated ginseng at a low temperature; cooling the separated honey at a room temperature; mixing the ginseng cooled at the low temperature and the honey cooled at the room temperature to form a second mixture material; aging the second mixture material at a low temperature; and acquiring ginseng from the second mixture material,wherein the cooling of the separated ginseng at the low temperature is performed in a temperature range of 2° C. to 6° C. for 12 to 24 hours such that a coupling force of the honey that penetrated into the separated ginseng and the separated ginseng is improved, and is performed in a state in which the separated ginseng is blocked from the outside such that the moisture in the interior of the ginseng is not extracted from the separated ...

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02-01-2020 дата публикации

Dairy gluten free no sugar added coconut milk frozen desert compositions and products

Номер: US20200000121A1
Принадлежит:

Described in preferred embodiments are dairy gluten free no sugar added coconut milk frozen desert compositions including a unique coconut milk, which have organoleptic qualities comparable to high fat frozen desserts such as ice cream. The compositions are composed of organic coconut milk comprising organic coconut solids and water, a sweetening agent and vegetable glycerin. Also described are dairy gluten free no sugar added flavors and inclusion compositions and methods for their production and incorporation into the dairy gluten free no sugar added coconut milk frozen desserts. Also provided are methods of making the frozen desert products. 1. A dairy gluten free no sugar added coconut milk composition suitable for preparing a frozen desert product , comprised of organic coconut milk comprising organic coconut solids and water , a sweetening agent and organic vegetable glycerin , the composition being free of added stabilizing gums , wherein the composition is capable of substantially retaining creaminess with substantially reduced iciness under conditions of freezing when the composition is aerated and frozen or is quiescently frozen providing a smooth , non greasy mouth feel.2. The composition of claim 1 , wherein the composition can be stored for up to 1 year at temperatures about −20 degrees F. (−28.9 degrees C.) and have ice crystals sized between about 30 and 80 microns.3. A composition according to comprising a sweetening agent in an amount of about 0.001-20 wt % claim 1 , coconut solids of about 22-40 wt % or a combination thereof claim 1 , the weight percentages being based on the total weight of the composition.4. A composition according to comprising a sweetening agent in an amount of about 0.001-20 wt % claim 1 , water in amount effective to achieve a total solids content of about 30-50% claim 1 , wherein the coconut solids are present in an amount of at least of about 22-40 wt % claim 1 , and the vegetable glycerin is present in an amount of about 5 ...

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02-01-2020 дата публикации

MOUTHFEEL ENHANCING COMPOSITION

Номер: US20200000126A1
Принадлежит:

This disclosure provides novel compositions comprising a compound of Formula I. These compositions are useful for improving mouthfeel properties of non-nutritive sweeteners, such as steviol glycosides and blends thereof, in food and beverages containing the same. 2. (canceled)4. The composition of claim 1 , wherein the compound of Formula I is present in the composition at a concentration of about 0.1 ppm to about 1000 ppm.5. (canceled)6. (canceled)7. The composition of claim 4 , wherein the compound of Formula I is present in the composition at a concentration of about 50 ppm to about 100 ppm.8. (canceled)9. The composition of claim 1 , wherein the composition is a beverage.10. The composition of claim 9 , wherein the compound of Formula I is present in the composition at a concentration of about 50 ppm to about 100 ppm.11. The composition of claim 1 , wherein the composition is a beverage concentrate.12. The composition of claim 11 , wherein the compound of Formula I is present in the composition at a concentration of about 300 ppm to about 600 ppm.13. The beverage of claim 9 , further comprising a non-nutritive sweetener.14. The beverage of claim 13 , wherein the non-nutritive sweetener is selected from the group consisting of a steviol glycoside claim 13 , Lo Han Guo sweetener claim 13 , rubusoside claim 13 , siamenoside claim 13 , monatin claim 13 , curculin claim 13 , glycyrrhizic acid claim 13 , neohesperidin claim 13 , dihydrochalcone claim 13 , glycyrrhizin claim 13 , glycyphyllin claim 13 , phloridzin claim 13 , trilobatin claim 13 , phyllodulcin claim 13 , brazzein claim 13 , hernandulcin claim 13 , osladin claim 13 , polypodoside A claim 13 , baiyunoside claim 13 , pterocaryoside A and B claim 13 , mukurozioside claim 13 , thaumatin claim 13 , monellin claim 13 , mabinlins I and II claim 13 , phlomisoside I claim 13 , periandrin I claim 13 , abrusoside A claim 13 , and cyclocarioside I claim 13 , mogroside IV claim 13 , mogroside V claim 13 , or ...

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05-01-2017 дата публикации

Methods for increasing the clarity and refreshing attributes and reducing the bitterness and astringency of green tea

Номер: US20170000150A1
Принадлежит: Nestec SA

Methods for modulating the bitterness and astringency of green tea, and nutritional products having a green tea with reduced bitterness and astringency, are provided. In a general embodiment, the methods comprise performing microfiltration on green tea extract to form a microfiltration retentate and a microfiltration permeate; performing at least one of ultrafiltration or reduced temperature fractionation on the microfiltration permeate; and using the ultrafiltration permeate from the ultrafiltration or the supernatant from the reduced temperature fractionation to make a green tea product. The ultrafiltration permeate or the supernatant can be further concentrated, spray or freeze dried to form a powder, used as a concentrate, or diluted to form a ready-to-drink beverage. In an embodiment, the ultrafiltration is performed on the microfiltration permeate to form an ultrafiltration retentate and an ultrafiltration permeate and then the reduced temperature fractionation is performed on the ultrafiltration permeate to form a supernatant and a sediment.

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11-01-2018 дата публикации

PROCESS AND FACILITY FOR PRODUCING A POWDERED POROUS PRODUCT

Номер: US20180007950A1
Принадлежит:

Disclosed is a process in which a viscous initial product having both a temperature of between 5° C. and 70° C. and a viscosity greater than 100 mPa·s is provided, —by way of a pump provided upstream of at least one aerator, the viscous initial product is transferred as it is to the at least one aerator in which the viscous initial product is mixed with a gas, injected into the aerator, so as to obtain a liquid foam continuously exiting the aerator, and—the liquid foam continuously exiting the at least one aerator is continuously pushed into the inlet of a treatment device which continuously divides and then dries this liquid foam so as to obtain a powdered porous product which has a solids content greater than 90%. 114-. (canceled)15. A method for producing a powdery porous product , wherein:a viscous initial product having both a temperature comprised between 5° C. and 70° C. and a viscosity greater than 100 mPa·s is provided,by means of a pump provided upstream from at least one aerator, the viscous initial product is transferred as such as far as said at least one aerator in which the viscous initial product is mixed with a gas, injected into the aerator, for obtaining a liquid foam continuously leaving the aerator, andthe liquid foam continuously leaving said at least one aerator is continuously pushed into an inlet of a treatment device which, continuously divides and then dries this liquid foam in order to obtain a powdery porous product which has a dry material level greater than 90%.16. The method according to claim 15 , wherein the specific gravity of the liquid foam leaving said at least one aerator is comprised between 25 and 80% of the specific gravity of the viscous initial liquid.17. The method according to claim 15 , wherein the liquid foam is continuously pushed from the outlet of said at least one aerator to the inlet of the treatment device either exclusively under the effect of the pressure prevailing in said at least one aerator claim 15 , or ...

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11-01-2018 дата публикации

NUTRITIONAL COMPOSITIONS COMPRISING HUMAN MILK OLIGOSACCHARIDES AND NUCLEOTIDES AND USES THEREOF FOR TREATING AND/OR PREVENTING ENTERIC VIRAL INFECTION

Номер: US20180008623A1
Принадлежит: ABBOTT LABORATORIES

Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases. 120-. (canceled)21. A synthetic pediatric formula comprising from about 0.01 mg/mL to about 10 mg/mL of a human milk oligosaccharide and from about 40 mg/L to about 320 mg/L of a nucleotide.22. The synthetic pediatric formula of claim 21 , wherein the human milk oligosaccharide is selected from 3′-fucosyllactose claim 21 , lacto-N-neotetraose claim 21 , 6′-sialyllactose claim 21 , 3′-sialyllactose claim 21 , sialic acid claim 21 , and combinations thereof.23. The synthetic pediatric formula of claim 22 , wherein the human milk oligosaccharide is lacto-N-neotetraose.24. The synthetic pediatric formula of claim 22 , wherein the human milk oligosaccharide is 3′-fucosyllactose.25. The synthetic pediatric formula of claim 22 , wherein the human milk oligosaccharide is selected from the group consisting of 3′-sialyllactose claim 22 , 6′-sialyllactose claim 22 , sialic acid claim 22 , and combinations thereof.26. The synthetic pediatric formula of claim 25 , wherein the human milk oligosaccharide comprises about 40 wt % 6′-sialyllactose claim 25 , about 10 wt % 3′-sialyllactose claim 25 , and about 50 wt % sialic acid.27. The synthetic pediatric formula of claim 21 , wherein the nucleotide is selected from the group consisting of cytidine 5′-monophosphate claim 21 , uridine 5′-monophosphate claim 21 , adenosine 5′-monophosphate claim 21 , guanosine 5′-monophosphate claim 21 , and combinations thereof.28. The synthetic pediatric formula of claim 27 , wherein the nucleotide comprises about 43% cytidine 5′-monophosphate claim 27 , about 18.5% uridine 5′-monophosphate claim 27 , about 16.5% adenosine 5′-monophosphate claim 27 , and about 22% guanosine 5′-monophosphate.29. The synthetic pediatric formula of claim 28 , wherein the ...

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17-01-2019 дата публикации

HIGHLY SOLUBLE STEVIOL GLYCOSIDES

Номер: US20190014805A1
Принадлежит: PURECIRCLE USA INC.

A method for making a highly soluble steviol glycoside composition is described. The resulting composition readily provides solutions with at least 0.5% concentration. 1. A method for producing a highly soluble steviol glycoside composition comprising the steps of:A) providing a powder composition comprising at least one steviol glycoside;B) providing water;C) mixing the water and powder composition comprising at least one steviol glycoside to make a mixture;D) increasing the temperature of the mixture to make a solution;E) decreasing the temperature of the solution to obtain solidified solution; andF) freeze drying the solidified solution, to provide highly soluble steviol glycoside composition having at least 0.5% solubility in water.2. The method of wherein steviol glycoside is selected from a group consisting of Rebaudioside A claim 1 , Rebaudioside B claim 1 , Rebaudioside C claim 1 , Rebaudioside D claim 1 , Rebaudioside E claim 1 , Rebaudioside F claim 1 , Rebaudioside G claim 1 , Rebaudioside H claim 1 , Rebaudioside I claim 1 , Rebaudioside J claim 1 , Rebaudioside K claim 1 , Rebaudioside L claim 1 , Rebaudioside M claim 1 , Rebaudioside N claim 1 , Rebaudioside O claim 1 , Rebaudioside Q claim 1 , Stevioside claim 1 , Steviolbioside claim 1 , Dulcoside A claim 1 , Rubusoside claim 1 , or other glycoside of steviol and combinations thereof.3. The method of wherein the water and powder composition comprising at least one steviol glycoside ratio is 10:1 (w/w).4. The method of wherein the water and powder composition comprising at least one steviol glycoside is heated to 80-100° C.5. The method of wherein solution is cooled down to −24° C. to −196° C. to obtain solidified solution.6. The method of wherein solidified solution is dried by a freeze drying apparatus.7. The method of claim 1 , wherein the highly soluble steviol glycoside composition solubility in water is about 2 grams per 100 grams of water.8. A highly soluble steviol glycoside composition powder ...

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16-01-2020 дата публикации

CURCUMIN INFUSED MILK BEVERAGE AND A PROCESS FOR THE PREPARATION THEREOF

Номер: US20200015489A1
Автор: MISRA Srikumar
Принадлежит:

A Curcumin infused milk beverage composition comprising 0.05% to 0.15% alkalized Curcumin, standardized milk with fat, sugar and stabilizing agents, wherein the pH of resultant composition is maintained at 6.8. 1. A process of preparing a Curcumin infused milk beverage comprising the steps of:adding standardized milk at a temperature of 4 to 8 degrees Celsius into a product mixing tank;adding an alkalized Curcumin solution, and a mixture of sugar and Carrageenan into the product mixing tank, wherein the quantity of sugar and Carrageenan are in the ratio of 10:1;mixing for 5 minutes with continuous agitation;transferring the final batch of the product to a Ready Beverage tank;adding flavour and colors to the Ready Beverage tank and mixing with continuous agitation; andprocessing the mixture at 140 degrees Celsius for 4 seconds with 250/50 bar upstream homogenization.2. The process of preparing a Curcumin infused milk beverage as claimed in claim 1 , wherein said standardized milk is maintained at a temperature of 6 to 8 degree Celsius.3. The process of preparing a Curcumin infused milk beverage as claimed in claim 1 , wherein said mixture of sugar and Carrageenan is a dry mixture prepared by adding sugar and Carrageenan at a ratio of 10:1 and mixing through a blender.4. The process of preparing a Curcumin infused milk beverage as claimed in claim 1 , wherein said alkaline Curcumin solution with particle size of 125 micrometers is calibrated to a concentration of 0.5% to 0.15% and a pH greater than 6.4 but less than 7.5. A process for preparing a Curcumin infused milk beverage comprising the steps of:taking a batch of 9000 kg milk at 4 to 8 degrees Celsius into a product mixing tank and standardize milk to have a specific fat content;preparing an alkalized Curcumin solution with particle size of 125 micrometers and a dry mixture of ten parts sugar and one-part Carrageenan;recirculation of the standardized milk through a blender;selecting PHE in Chilling profile and ...

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16-01-2020 дата публикации

PARTICULATE HEALTH FOOD

Номер: US20200015506A1
Автор: CHIBA Machiko
Принадлежит:

A particulate health food includes 100 parts by mass of particulate powdered wood ear mushrooms having a particle diameter of 125 to 250 μm, and 15 to 35 parts by mass of matcha having a particle diameter of 1 to 100 μm. A matcha particle of a relatively large particle size and a matcha particle of a relatively small particle size are closely loaded onto surfaces of a powdered wood ear mushroom such that the small matcha particle enters a gap between the large matcha particles. Matcha particles having two different particle diameters and having a brighter color than wood ear mushrooms firmly adhere to surfaces of the powdered wood ear mushroom so that the matcha particles are integrated and become hard to separate from each other even under vibration, and the powdered wood ear mushroom is made more palatable. 1. A particulate health food comprising a particulate composition that includes wood ear mushrooms as a main component , the wood ear mushrooms comprising powdered particulate dry wood ear mushrooms having a particle diameter of 125 to 250 μm , and wherein the particulate composition further includes , based on 100 parts by mass of the wood ear mushrooms , 15 to 35 parts by mass of matcha having a particle diameter of 1 to 100 μm.2. The particulate health food according to claim 1 , wherein the matcha has a particle-size distribution in which peaks appear at 3 to 10 μm and 20 to 40 μm.3. The particulate health food according to claim 1 , wherein the particulate health food is a granular particulate composition.4. A capsuled particulate health food claim 1 , wherein the particulate health food according to is contained in a capsule ingestible with a liquid.5. The particulate health food according to claim 2 , wherein the particulate health food is a granular particulate composition.6. A capsuled particulate health food claim 2 , wherein the particulate health food according to is contained in a capsule ingestible with a liquid.7. A capsuled particulate health ...

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16-01-2020 дата публикации

Novel Triterpene-Glycoside as Sweetener or Sweetener Enhancer

Номер: US20200017541A1
Принадлежит: ANALYTICON DISCOVERY GMBH

What claimed is a method of sweetening or enhancing sweetening effect of a composition that is administered orally to an individual by adding a specific triterpene glycoside obtained from Momordica grosvenorii ( Siraitia grosvenori ).

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25-01-2018 дата публикации

NUTRITIONAL APPROACH TO THE CONTROL OF ANEMIA, DIABETES AND OTHER DISEASES OR CONDITIONS AND PREVENTION OF ASSOCIATED COMORBID STATES WITH THE USE OF ERGOTHIONEINE

Номер: US20180021405A1
Автор: Hausman Marvin S.
Принадлежит:

Nutritional products, compositions, pharmaceutical preparations and methods of use are disclosed for the prevention, suppression and treatment of anemia and/or diabetes and its various associated comorbidities. Uses of Ergothioneine to neutralize free radicals and/or cytokines, reduce oxidative stress, prevent inflammation, stimulate red blood cell production with increased levels of hemoglobin, and/or stabilize iron in its normal 2 charge for proper oxygen binding and carrying are further disclosed. The extraction of Ergothioneine from whole food sources and bacterium for use in nutritional products, compositions, pharmaceutical preparations and treatments is also disclosed. 1: A method of treating anemia in mammals comprising:producing a source of Ergothioneine and Vitamin D comprising UV irradiating filamentous fungi and/or tissue, substrate, spent substrate, or component thereof, to generate said source of Ergothioneine and Vitamin D having higher levels of Vitamin D than a nonirradiated product; andadministering to said mammal in need of treatment for anemia said source of Ergothioneine and Vitamin D, wherein the anemia is not due to nutritional iron deficiency; and{'sup': '+', 'neutralizing free radical damage, maintaining iron in the 2 oxidation state in said mammal, and promoting blood cell development and hemoglobin production in said mammal.'}2: The method of wherein said Vitamin D is Vitamin Dand/or Vitamin D.3: The method of further comprising obtaining a source of Ergothioneine from a whole food and/or bacteria source.4Spirulina: The method of wherein said source is the cyanobacteria or a cereal crop (e.g. oat claim 3 , barley claim 3 , hops).5. (canceled)6Agaricus bisporus, Agaricus blazei, Lentinula edodes, Pleurotus ostreatusPleurotus erymgii: The method of wherein said filmentous fungi is a mushroom of a species selected from the group consisting of: claim 1 , and and wherein said mushroom is enriched by pulsed UV irradiation without changing said ...

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24-01-2019 дата публикации

Granulation of a stevia sweetener

Номер: US20190021356A1
Принадлежит: PureCircle Sdn Bhd

A method for making a granulated Stevia sweetener is described. The resulting sweetener has a desirably high solubility level.

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24-01-2019 дата публикации

LONG-LASTING SWEETENER FORMULATIONS

Номер: US20190021382A1
Принадлежит:

Long-lasting sweetener formulations which comprise at least one encapsulated sweetener compound and are suitable for use in confectionery products are disclosed. In certain, non-limiting embodiments of the disclosed formulations, the sweetener compound is stevioside, rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, rebaudioside E, rebaudioside F, rebaudioside M, steviobioside, rubusoside and dulcoside A. In certain embodiments, the disclosed formulations provide enhanced sweetness duration for chewing gum. 1. A sweetener composition comprising at least one encapsulated compound selected from the group consisting of stevioside , rebaudioside A , rebaudioside B , rebaudioside C , rebaudioside D , rebaudioside E , rebaudioside F , rebaudioside M , steviobioside , rubusoside and dulcoside A , and combinations thereof.2. The sweetener composition of claim 1 , wherein the at least one encapsulated compound is selected from the group consisting of rebaudioside A claim 1 , rebaudioside D claim 1 , rebaudioside M claim 1 , and combinations thereof.3. The sweetener composition of claim 1 , wherein the at least one encapsulated compound is partially encapsulated.4. The sweetener composition of claim 1 , wherein the ratio of rebaudioside A to rebaudioside M is from 1:1 to 3:1.5. The sweetener composition of claim 1 , wherein the ratio of rebaudioside A to rebaudioside D is from 1:1 to 3:1.6. The sweetener composition of claim 1 , wherein the ratio rebaudioside A to rebaudioside M is 1:3.7. The sweetener composition of claim 1 , wherein the ratio rebaudioside A to rebaudioside D is 1:3.8. The sweetener composition of claim 1 , wherein the encapsulating material of the at least one encapsulated compound is selected from the group consisting of starch claim 1 , modified starch and combinations thereof.9. The sweetener composition of claim 1 , wherein the encapsulating material of the at least one encapsulated compound is selected from the group consisting of ...

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24-01-2019 дата публикации

BLENDS OF OKARA AND A FIBER-CONTAINING PECTIN PRODUCT

Номер: US20190021383A1
Принадлежит:

Provided is a composition which comprises (a) okara or whole soy or a mixture thereof, and (b) a fiber-containing pectin product or pectin, wherein the weight ratio between components (a) and (b) is from 0.1:1 to 75:1. The composition is useful for increasing the cohesion of solid food, such as soy patties. 1. A composition comprising(a) okara, and 'wherein the weight ratio between components (a) and (b) is from 4:1 to 6:1.', '(b) a fiber-containing pectin product,'}2. The composition of comprising from 0.5 to 15 weight percent of component (a) claim 1 , based on the total weight of the composition.3. The composition of comprising from 0.2 to 5 weight percent of component (b) claim 1 , based on the total weight of the composition.4. The composition of comprising at least 4 weight percent of component (a) claim 1 , based on the total weight of the composition.5. The composition of additionally comprising from 20 to 80 weight percent of water claim 1 , based on the weight of the composition.6. The composition of additionally comprising from 5 to 80 weight percent claim 1 , based on the weight of the composition claim 1 , of one or more dry ingredients selected from the group consisting of sodium chloride claim 1 , one or more sugars claim 1 , flavoring agents claim 1 , gluten claim 1 , one or more proteins in a form different from okara or whole soy claim 1 , and mixtures thereof.7. The composition of comprising from 5 to 40 weight percent of one or more plant proteins in a form different from okara and different from whole soy.8. The composition of in the form of a solid food composition.9. The composition of being a soy patty.10. A method of improving one or more of the properties of a food composition selected from cohesion claim 8 , firmness claim 8 , juiciness claim 8 , freeze thaw stability or texture; resistance to shrinking during cooking claim 8 , or boil-out control claim 8 , which method comprises the step of incorporating into the composition a combination ...

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24-01-2019 дата публикации

OLIGOSACCHARIDE COMPOSITION, METHOD, AND USE THEREOF

Номер: US20190021384A1
Принадлежит: CARGILL INCORPORATED

The invention provides oligosaccharide compositions, wherein arabinoxylan is present in said composition in amounts of 40-70% (w/w) of dry solid con-tent (DS) and the oligosaccharides have a dispersity (D) of 10-17. The oligosaccharide compositions are useful as bulking agents and for increasing the mouthfeel of a food product. 1. An Oligosaccharide composition comprising:i) 40-70% (w/w) DS arabinoxylan; andii) oligosaccharides having a dispersity (Ð) of 10-17.2. The oligosaccharide composition according to claim 1 , wherein the arabinose:xylose ratio in said arabinoxylan is 0.5 or higher.3. The oligosaccharide composition according to claim 1 , wherein said oligosaccharides have a weight average molecular weight of 10 claim 1 ,000-100 claim 1 ,000 daltons.4. The oligosaccharide composition according to claim 1 , wherein the amount of monosaccharides is 10% (w/w) of the amount of dry solids or more claim 1 , such as within the range of 10-40% (w/w) of the amount of dry solids.5. The oligosaccharide composition claim 1 , according to claim 1 , wherein the oligosaccharide composition is a stable syrup having a dry solid content of 60% (w/w) or more.6. The oligosaccharide composition according to claim 1 , wherein the viscosity of said composition at 24° C. and 10% (w/w) DS ranges from 2.0-6.0 cps claim 1 , preferably 2.5-5.5 cps.7. The oligosaccharide composition according to claim 1 , wherein the composition has shear thinning behavior at 30% (w/w) DS or more claim 1 , such as 40% (w/w) DS or more.8. The oligosaccharide composition according to claim 1 , wherein said composition is characterized by a tribological profile comprising a Boundary Regime at a sliding speed of less than 1 mm/s and a Mixed Regime at a sliding speed from 1-200 mm/s when the friction factor (coefficient of friction) for the oligosaccharide composition is determined in a tribometer as a function of sliding speed claim 1 , using elastimer plate(s) as sliding surface(s).9. The oligosaccharide ...

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10-02-2022 дата публикации

Compositions and methods for nutritional supplements

Номер: US20220040251A1
Автор: Hartley Pond
Принадлежит: DailyColors Health Inc

Compositions and methods are presented in which a plurality of chemically distinct polyphenols inhibit multiple enzymes in pathways associated with health and healthy ageing. Preferred compositions are derived from colored plant materials that are commonly found in the Mediterranean diet and provide the biochemical basis for the health benefits of the Mediterranean diet. Notably, the enzyme inhibition observed with the combined polyphenols was synergistic with respect to not one but a significant number of enzymes in the pathways associated with health and healthy ageing, thus providing an amplified desirable effect.

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24-01-2019 дата публикации

POLYPHENOL-REACTIVE OXYGEN SPECIES COMPOSITIONS AND METHODS

Номер: US20190022056A1
Принадлежит:

Disclosed herein are nutraceutical compositions comprising or consisting essentially of one or more types of polyphenols (e.g., a green tea polyphenol) and one or more types of reactive oxygen species, and methods for their use to treat gastrointestinal conditions, inflammatory conditions, and immune conditions. 1. A nutraceutical composition comprising at least one polyphenol and at least one reactive oxygen species , wherein the at least one polyphenol is present at a final concentration from about 0.001% to about 0.009% , and wherein the at least one reactive oxygen species is present at a final concentration from about 0.01% to about 0.09%.2. The composition of claim 1 , wherein when orally administered to a human subject suffering from diarrhea claim 1 , the composition prevents the subject from having an unformed stool as soon as about 5 minutes to about 6.5 hours after ingestion of the nutraceutical composition.3. The composition of claim 1 , wherein when orally administered to a human subject suffering from diarrhea claim 1 , the composition prevents the subject from having an unformed stool at least 2-fold faster as compared to a subject suffering from diarrhea who ingests a composition that does not comprise a reactive oxygen species and/or at least one polyphenol claim 1 , or as compared to a subject suffering from diarrhea who ingests a composition that comprises at least one polyphenol at a final concentration greater than 0.01% and a reactive oxygen species at a final concentration greater than 0.1%.4. The composition of claim 1 , wherein the at least one polyphenol is present at a final concentration from about 0.002% to about 0.008% claim 1 , from about 0.003% to about 0.007% claim 1 , from about 0.004% to about 0.006% claim 1 , from about 0.003% to about 0.005% claim 1 , or about 0.004%.5. The composition of claim 1 , wherein the at least one reactive oxygen species is present at a final concentration from about 0.02% to about 0.08% claim 1 , from ...

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24-01-2019 дата публикации

FOOD COMPOSITION FOR PREVENTING AND ALLEVIATING FEMALE MENOPAUSE SYMPTOMS CONTAINING GRAPE SEED EXTRACT, VALERIAN EXTRACT AND SAFFLOWER SEED EXTRACT

Номер: US20190022163A1
Автор: Kim Ji Hoon, SHIM Tae Jin
Принадлежит: FromBio Co., Ltd

Provided is a food composition for preventing and alleviating female menopause symptoms containing a grape seed extract, a valerian extract and a safflower seed extract. 1. A food composition for preventing and alleviating female menopause symptoms comprising , as an active ingredient , a combination of a grape seed extract , a valerian extract and a safflower seed extract.2. The food composition according to claim 1 , wherein the combination is a combination comprising 10 to 40% by weight of the grape seed extract claim 1 , 15 to 50% by weight of the valerian extract and 30 to 70% by weight of the safflower seed extract.3. The food composition according to claim 1 , wherein the grape seed extract claim 1 , the valerian extract and the safflower seed extract are each extracted with water claim 1 , a C1 to C4 lower alcohol or a mixture thereof as an extraction solvent.4. The food composition according to claim 1 , wherein the combination is present in an amount of 0.01 to 50% by weight with respect to the total weight of the food composition.5. A method of preventing or alleviating a female menopause symptom in a subject in need thereof comprising administering the composition of to the subject.6. The method of claim 5 , wherein the composition comprises 10 to 40% by weight of the grape seed extract claim 5 , 15 to 50% by weight of the valerian extract and 30 to 70% by weight of the safflower seed extract.7. The method of claim 5 , wherein the grape seed extract claim 5 , the valerian extract and the safflower seed extract are each an extract of water claim 5 , an extract of a C1 to C4 lower alcohol or an extract of the mixture thereof.8. The method of claim 5 , wherein the combination is present in an amount of 0.01 to 50% by weight with respect to the total weight of the composition. The present invention relates to a food composition for preventing and alleviating female menopause symptoms containing a grape seed extract, a valerian extract and a safflower seed ...

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23-01-2020 дата публикации

CONSUMABLES

Номер: US20200022387A1
Принадлежит:

Disclosed are sweetened consumables and methods of forming said sweetened consumables that comprise certain sweeteners and a compound of formula (1), 1. A method of sweetening consumables comprising admixing to a consumable:a) at least 0.0001% (w/w) of at least one sweetener, including natural and artificial sweeteners, wherein said sweetener includes sucrose, fructose, glucose, high fructose corn syrup, corn syrup, xylose, arabinose, rhamnose, erythritol, xylitol, mannitol, sorbitol, inositol, acesulfame potassium, aspartame, neotame, sucralose, saccharine, or combinations thereof,wherein said at least one sweetener or sweetener combination is present in a concentration above the sweetness detection threshold in a concentration isosweet from 2% to 15% sucrose, andb) hesperitin dihydrochalcone 4″-beta-D-glucoside (HDG) in a concentration near its sweetness detection threshold.2. The method according to claim 1 , wherein the HDG concentration is from 0.3 to 20 ppm.3. The method according to claim 1 , wherein the consumable is selected from dairy product claim 1 , dairy-derived product and dairy-alternative product and wherein the HDG concentration is from 1 to 75 ppm.4. The method according to claim 1 , wherein the consumable has a pH below 6.5 and the HDG concentration is from 0.6 to 30 ppm.5. The method according to claim 1 , wherein the consumable has a pH below 5 and the HDG concentration is from 0.6 to 40 ppm.6. The method according to claim 1 , wherein the consumable is a water-based consumable selected from the group consisting of water claim 1 , aqueous beverage claim 1 , enhanced/slightly sweetened water drink claim 1 , mineral water claim 1 , carbonated beverage claim 1 , non-carbonated beverage claim 1 , carbonated water claim 1 , still water claim 1 , soft drink claim 1 , non-alcoholic drink claim 1 , alcoholic drink claim 1 , beer claim 1 , wine claim 1 , liquor claim 1 , fruit drink claim 1 , juice claim 1 , fruit juice claim 1 , vegetable juice claim 1 ...

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23-01-2020 дата публикации

NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF

Номер: US20200022996A1
Принадлежит: ABBOTT LABORATORIES

Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases. 1. A synthetic pediatric formula in powder or liquid form wherein , when the formula is a liquid , the formula comprises:a human milk oligosaccharide component comprising a human milk oligosaccharide selected form the group consisting of 6′-sialyllactose, 3′-sialyllactose 2′-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, lacto-N-neotetraose, lacto-N-fucopentaose, and combinations thereof;from about 5 mg per 100 kcals to 23 mg per 100 kcals of a long chain polyunsaturated fatty acid component comprising docosahexaenoic acid and arachidonic acid;from about 0.001 μg/mL to about 5 μg/mL of a carotenoid component comprising lutein, lycopene, beta-carotene, or a combination thereof;from about 10 mg/L to about 200 mg/L of a monomeric monophosphate nucleotide component;wherein from about 7% to about 40% of total calories in the formula are derived from protein, from about 25% to about 50% of total calories in the formula are derived from fat, and from about 35% to about 55% of total calories in the formula are derived from carbohydrates; andwherein the synthetic pediatric formula is shelf stable for at least 3 months.2. The synthetic pediatric formula of comprising 0.01 mg/mL to about 5 mg/mL of the human milk oligosaccharide component comprising 2′-fucosyllactose and 6′-sialyllactose.3. The synthetic pediatric formula of claim 1 , wherein the human milk oligosaccharide component comprises 2′-fucosyllactose which is present in a concentration of from about 0.01 mg/mL to less than 2 mg/mL.4. The synthetic pediatric formula of claim 1 , wherein the docosahexaenoic acid is present at a concentration of from about 0.025 mg/mL to about 0.130 mg/mL and the arachidonic acid ...

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02-02-2017 дата публикации

Functional beverage

Номер: US20170027194A1
Принадлежит: Lotte Fine Chemical Co Ltd

A functional beverage is disclosed. The disclosed functional beverage comprises a mother liquor and a liquid additive, wherein the liquid additive comprises a poorly water-soluble natural product, an edible surfactant, an edible cosurfactant, and edible oil.

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01-02-2018 дата публикации

Composition for reducing food intake

Номер: US20180027860A1
Принадлежит: Natures Remedies Ltd

The present invention features a composition and method for suppressing appetite. The composition of the invention is composed of yerbe maté extract, guarana extract, and damiana extract in combination with a dietary fiber.

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01-02-2018 дата публикации

PROBIOTIC AND POLYPHENOL AGAINST NEURODEGENERATION

Номер: US20180028582A1
Принадлежит:

A composition containing the probiotic strain CNCM 1-1225 in combination with a polyphenol for use in the treatment or prevention of a cognitive and/or neurodegenerative disorder, in particular Alzheimer's disease. The polyphenol can be one or more of rosmarinic acid, chicoric acid, or caftaric acid, and can be provided in the form of a plant extract. 1Lactobacillus johnsonii. A method for treatment of Alzheimer's disease , the method comprising the step of administering a composition comprising CNCM I-1225 in combination with a polyphenol to an individual in need of same.2. The method according to claim 1 , wherein the polyphenol is selected from the group consisting of rosmarinic acid claim 1 , chicoric acid claim 1 , caftaric acid claim 1 , and combinations thereof.3. The method according to claim 1 , wherein the polyphenol is provided in the form of a plant extract.4. The method according to claim 3 , wherein the rosmarinic acid is provided in the form of a rosemary extract.5. The method according to claim 1 , wherein the polyphenol is provided in the form of a pharmaceutically accepted salt.6Lactobacillus johnsonii. The method according to claim 1 , wherein the CNCM I-1225 is in the form of viable bacteria or non-replicating bacteria.7Lactobacillus johnsonii. The method according to claim 1 , wherein the composition comprises the CNCM I-1225 in an amount of between 10and 10cfu/g dry mass of the composition.8Lactobacillus johnsonii. The method according to claim 1 , wherein the CNCM I-1225 is encapsulated.9. The method according to claim 1 , wherein the individual in need of same is a human or pet.10. The method according to claim 1 , wherein the composition is selected from the group consisting of food products claim 1 , animal food products claim 1 , pharmaceutical compositions claim 1 , nutritional formulations claim 1 , nutraceuticals claim 1 , beverages claim 1 , food supplements claim 1 , and food additives.11. The method according to claim 1 , wherein the ...

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31-01-2019 дата публикации

CACAO-DERIVED WATER EXTRACT, FOOD AND DRINK CONTAINING SAME, METHOD FOR MANUFACTURING CACAO EXTRACT, AND METHOD FOR EXTRACTING POLYPHENOL

Номер: US20190029288A1
Принадлежит:

Provided is cacao extract with better flavor and in which miscellaneous flavor is reduced, and a method for producing such cacao extract. The cacao-derived water extract of the present invention contains polyphenol. In this cacao water extract, the ratio of a total mass of dimeric to tetrameric proanthocyanidins to a total mass of monomeric to octameric proanthocyanidins is 40% or more. Also, in this method for producing cacao extract, an active ingredient such as polyphenol is extracted from a cacao raw material such as cacao powder using water adjusted to a temperature within a range from 50° C. to 90° C. inclusive and to a pH within a range from 2.0 to 5.0 inclusive. 1. A cacao-derived water extract containing polyphenol , whereinthe polyphenol includes proanthocyanidins, anda ratio of a total mass of dimeric proanthocyanidins, trimeric proanthocyanidins and tetrameric proanthocyanidins to a total mass of monomeric to octameric proanthocyanidins is 40% or more.2. The cacao-derived water extract according to claim 1 , wherein a ratio of a total mass of dimeric proanthocyanidins claim 1 , trimeric proanthocyanidins and tetrameric proanthocyanidins to a total mass of monomeric to octameric proanthocyanidins is 51% or more.3. The cacao-derived water extract according to claim 1 ,wherein procyanidin B2 and catechin are contained as the polyphenol, andthe ratio of a mass of the procyanidin B2 to a mass of the catechin is within a range from 5 to 20 inclusive.4. The cacao-derived water extract according to claim 1 , wherein the polyphenol contains no octameric proanthocyanidins.5. The cacao-derived water extract according to claim 1 , the cacao-derived water extract including theobromine with a concentration within a range from 5 mg/g to 20 mg/g inclusive.6. A food or drink comprising the cacao-derived water extract according to .7. A method for producing a cacao extract claim 1 , comprising:providing a cacao or a cacao processed product as a raw material; andextracting ...

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31-01-2019 дата публикации

WHEY PROTEIN BASED LIQUID NUTRITIONAL COMPOSITION

Номер: US20190029305A1
Автор: PONCE Richard
Принадлежит:

Whey protein based liquid nutritional compositions are provided. The liquid nutritional compositions include at least 7% by weight protein and all of the protein is provided by a whey protein hydrolysate and an intact whey protein. The liquid nutritional compositions have a neutral pH, a low viscosity, and are shelf stable. 1. A liquid nutritional composition comprising:at least 7% by weight protein, wherein the protein consists of a whey protein hydrolysate and an intact whey protein;wherein the liquid nutritional composition has a pH of 6.4 to 7.5, a viscosity of 5 cps to 30 cps, and is shelf stable.2. The liquid nutritional composition according to claim 1 , wherein the liquid nutritional composition is substantially free of carbohydrates.3. The liquid nutritional composition according to claim 1 , wherein a weight ratio of the whey protein hydrolysate to the intact whey protein is from 1:4 to 4:1.4. The liquid nutritional composition according to claim 1 , wherein a weight ratio of the whey protein hydrolysate to the intact whey protein is 1:1.5. The liquid nutritional composition according to claim 1 , wherein the intact whey protein is at least one of a whey protein concentrate and a whey protein isolate.6. The liquid nutritional composition according to claim 1 , wherein the whey protein hydrolysate has a degree of hydrolysis of 5% to 30%.7. The liquid nutritional composition according to claim 1 , wherein the whey protein hydrolysate has a degree of hydrolysis of 10% to 12%.8. The liquid nutritional composition according to claim 1 , further comprising from 1 claim 1 ,500 ppm to 3 claim 1 ,000 ppm of a stabilizer component.9. The liquid nutritional composition according to claim 8 , wherein the stabilizer component comprises at least one of microcrystalline cellulose claim 8 , carboxymethylcellulose claim 8 , gellan gum claim 8 , and carrageenan.10. The liquid nutritional composition according to claim 1 , further comprising a fat claim 1 , wherein the fat ...

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31-01-2019 дата публикации

COMPOSITION FOR USE IN THE PREVENTION AND/OR TREATMENT OF SKIN CONDITIONS AND SKIN DISEASES

Номер: US20190029306A1
Принадлежит: NESTEC S.A.

The invention discloses a composition comprising oligosaccharide, for use in the prevention and/or treatmentof skin conditions and/or skin diseases by increasing SCFA, in particular colonic propionate and butyrate. Said skin disease is in particular atopic dermatitis. 1. A method for the prevention and/or treatment of skin conditions and/or skin diseases in an infant or young child by increasing SCFA production in such infant or young child comprising administering a composition comprising an oligosaccharide mixture to an infant or young child in need of same.2. A method according to claim 1 , wherein the oligosaccharide mixture comprises at least one N-acetylated oligosaccharide claim 1 , at least one galacto-oligosaccharide and at least one sialylated oligosaccharide.3. A method according to claim 1 , wherein the oligosaccharide mixture comprises from 0.1 to 4.0 wt % of N-acetylated oligosaccharide(s) claim 1 , from 92.0 to 99.5 wt % of the galacto-oligosaccharide(s) and from 0.2 to 4.0 wt % of the sialylated oligosaccharide(s).4. A method according to claim 1 , wherein the composition comprises at least 0.01 wt % of N-acetylated oligosaccharide(s) claim 1 , at least 2.0 wt % of galacto-oligosaccharide(s) and at least 0.02 wt % of sialylated oligosaccharide(s).5. A method according to claim 1 , wherein the composition comprises a prebiotic claim 1 , said the prebiotic being selected from the group consisting of human milk oligosaccharides claim 1 , fructo-oligosaccharide claim 1 , inulin claim 1 , xylooligosaccharides claim 1 , polydextrose and combinations thereof.6Lactobacillus acidophilus, Lactobacillus salivarius, Lactobacillus rhamnosus, Lactobacillus paracasei, Lactobacillus casei, Lactobacillus johnsonii, Lactobacillus plantarum, Lactobacillus fermentum, Lactobacillus lactis, Lactobacillus delbrueckii, Lactobacillus helveticus, Lactobacillus bulgari, Lactococcus lactis, Lactococcus diacetylactis, Lactococcus cremoris, Streptococcus salivarius, Streptococcus ...

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31-01-2019 дата публикации

HUMAN MILK OLIGOSACCHARIDES AGAINST LATER IN LIFE EXCESSIVE FAT MASS ACCUMULATION AND RELATED HEALTH DISORDERS

Номер: US20190029308A1
Принадлежит:

The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide for use in an infant or a young child for reducing and/or preventing later in life excessive fat mass accumulation and/or a health disorder related to excessive fat mass accumulation, wherein said fucosylated oligosaccharide has at least one fucose group attached by an alpha 1,3 linkage, at least one fucose group attached by an alpha 1,4 linkage, or combinations thereof. The invention also relates to nutritional composition for use to promote healthy growth. 1. A method for reducing and/or avoiding in an infant or young child later in life excessive fat mass accumulation and/or a later in life health disorder related to excessive fat mass accumulation comprising administering a nutritional composition comprising at least one fucosylated oligosaccharide to an infant or young child wherein the fucosylated oligosaccharide has at least one fucose group attached by an alpha 1 ,3 linkage , at least one fucose group attached by an alpha 1 ,4 linkage , or combinations thereof.2. Method according to wherein the composition comprises at least one fucosylated oligosaccharide which is fucosylated by FUT3.3. Method according to claim 1 , wherein the at least one fucosylated oligosaccharide is selected from the group consisting of 3′ fucosylated lactose (3FL) claim 1 , DFL claim 1 , LNFP II claim 1 , LNFP III claim 1 , LNFP V claim 1 , and combinations thereof.4. Method according to wherein the at least one fucosylated oligosaccharide is selected from the group consisting of 3′ fucosylated lactose claim 1 , DFL and combinations thereof.5. Method according to wherein the health disorder related to excessive fat mass accumulation is selected from the group consisting of overweight claim 1 , obesity claim 1 , type 2 diabetes claim 1 , insulin resistance claim 1 , hypertension claim 1 , cardiovascular disease or metabolic syndrome and premature adiposity rebound.6. Method ...

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01-02-2018 дата публикации

Fiber-Containing Carbohydrate Composition

Номер: US20180030489A1
Принадлежит: Tate & Lyle Ingredients Americas LLC

A food product comprises an oligosaccharide composition that is digestion resistant or slowly digestible. The oligosaccharide composition can be produced by a process that comprises producing an aqueous composition that comprises at least one oligosaccharide and at least one monosaccharide by saccharification of starch, membrane filtering the aqueous composition to form a monosaccharide-rich stream and an oligosaccharide-rich stream, and recovering the oligosaccharide-rich stream. Alternatively, the oligosaccharide composition can be produced by a process that comprises heating an aqueous feed composition that comprises at least one monosaccharide or linear saccharide oligomer, and that has a solids concentration of at least about 70% by weight, to a temperature of at least about 40° C., and contacting the feed composition with at least one catalyst that accelerates the rate of cleavage or formation of glucosyl bonds for a time sufficient to cause formation of non-linear saccharide oligomers, wherein a product composition is produced that contains a higher concentration of non-linear saccharide oligomers than linear saccharide oligomers. 1. A process for making a slowly-digestible or digestion-resistant carbohydrate composition , the process comprisingproviding an aqueous feed composition that comprises dextrose, the aqueous feed composition including at least 70% by weight on a dry solids basis of monosaccharides and oligosaccharides; andreacting the aqueous feed composition at a solids concentration of at least 90% by weight in the presence of at least one acid catalyst that accelerates the rate of cleavage or formation of glucosyl bonds at a pH of no more than 4 and a temperature of at least about 149° C. for a time in the range of 0.1-15 minutes sufficient to produce a product saccharide composition in which the concentration of non-linear saccharide oligomers is at least twice as high as the concentration of linear saccharide oligomers, and in which the ...

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30-01-2020 дата публикации

Method for producing fermented bamboo extract and immunostimulating agent

Номер: US20200029610A1
Автор: Osamu TAMAI
Принадлежит: Individual

An object of the present invention is to provide a new application of bamboo based on new functions. A method for producing a fermented bamboo extract comprises a pulverization step of pulverizing bamboo to obtain bamboo powder, a fermentation step of fermenting the bamboo powder with lactic acid bacteria to obtain a fermented bamboo product, and an extraction step of subjecting the fermented bamboo product to hot water extraction to obtain an extract.

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08-02-2018 дата публикации

COMPOSITIONS AND METHODS OF TREATING VIRAL INFECTIONS

Номер: US20180036358A1
Автор: REMMEREIT Jan
Принадлежит:

The present invention relates to the field of nutraceuticals, and in particular to nutraceuticals comprising sulfated polysaccharides, Astragalus polysaccharides, resveratrol, and combinations thereof. These compositions find use in inducing physiological responses such, decreasing body fat, increasing lean body mass, alleviating the symptoms of colds, preventing the onset of colds, increasing energy, increasing the feeling of well-being in subjects, and improving skin tone and appearance. 1. A method of inducing a physiological effect selected from the group consisting of alleviation of the symptoms of viral induced obesity , preventing viral induced obesity increasing lean body mass , decreasing body fat , increasing energy , increasing the feeling of well-being , alleviation of cold symptoms , and improving the skin tone , roughness and appearance in a subject comprising:providing a composition comprising effective amounts of a sulfated polysaccharide and a sialic acid,and orally administering said composition to said patient under conditions such that said physiological effect is induced.2. The method of claim 1 , wherein said symptom is obesity.3. The method of claim 1 , wherein said administration of said composition induces weight reduction in a subject.4. The method of claim 1 , wherein said administration of said composition increases the lean body mass of said subject.5. The method of claim 1 , wherein said administration of said composition reduces cellulite in said subject.6. The method of claim 1 , wherein said administration of said composition improves a skin parameter selected from the group consisting of improved skin tone claim 1 , improved skin tightness in said subject and improved skin roughness.7. The method of claim 1 , wherein said administration of said composition reduces body fat in said subject.8. The method of claim 1 , wherein said composition is a dietary supplement.9. The method of claim 1 , wherein said composition is a nutritional ...

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24-02-2022 дата публикации

OLIGOSACCHARIDE SYRUP HAVING IMPROVED STABILITY

Номер: US20220053810A1
Принадлежит:

The present invention relates to a saccharide syrup composition comprising an organic acid or its salt and an oligosaccharide, and more specifically, the saccharide syrup composition comprises allulose. 1. A method for preventing oligosaccharide decomposition , by adding an organic acid or its salt of 0.001 to 1.0 wt % to a saccharide syrup composition comprising the oligosaccharide.2. The method according to claim 1 , wherein the organic acid is one or more selected from the group consisting of lactic acid claim 1 , citric acid and ascorbic acid.3. The method according to claim 1 , wherein the oligosaccharide content is 20 to 90 wt % claim 1 , based on 100 wt % of the saccharide syrup composition.4. The method according to claim 1 , wherein the oligosaccharide content is 20 to 90 wt % and the allulose content is 10 to 80 wt % claim 1 , based on 100 wt % of the saccharide syrup composition.5. The method according to claim 1 , wherein the oligosaccharide is one or more kinds selected from the group consisting of galacto-oligosaccharide claim 1 , malto-oligosaccharide claim 1 , isomalto-oligosaccharide claim 1 , fructo-oligosaccharide and soy oligosaccharide.6. The method according to claim 1 , wherein the saccharide syrup composition added by the organic acid or its salt has an electrical conductivity of 100 to 1000 μS/cm.7. The method according to claim 1 , wherein pH of the saccharide syrup composition is 5.0 to 8.0.8. The method according to claim 1 , wherein the color value of the saccharide syrup composition is 0.005 to 0.2.9. The method according to claim 1 , wherein the preventing oligosaccharide decomposition is to have a content of the oligosaccharide of 80% or more claim 1 , based on 100% of the initial content of the oligosaccharide claim 1 , under storage conditions of a temperature of 45° C. and 42 days.10. The method according to claim 1 , wherein the saccharide syrup composition further comprises allulose syrup.11. The method according to claim 1 , ...

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07-02-2019 дата публикации

Molded Food Product and Method for Producing Same

Номер: US20190037895A1
Автор: SHIRAISHI Satomi
Принадлежит:

A molded food product which has an excellent shape retention property as well as causes little scorch of the ingredient, particularly carbonization of carbohydrates during production, and a method for producing such molded food product are provided. The molded food product contains a binder including a koji-fermented grain liquid composition. The fermented grain liquid composition is preferably amazake, sake cake, or mixtures thereof. 1. A molded food product comprising a binder including a koji-fermented grain liquid composition.2. The molded food product according to claim 1 , wherein the fermented grain liquid composition is one selected from the group consisting of amazake claim 1 , sake cake claim 1 , and mixtures thereof.3. The molded food product according to claim 1 , wherein the content of the binder is 30% or more by weight with respect to the total solid content of the molded food product.4. The molded food product according to claim 1 , wherein the moisture content is 20% or less.5. The molded food product according to claim 1 , wherein the molded food product is dehydrated by air-drying at a temperature of 105° F. to 160° F.6. The molded food product according to claim 1 , further comprising edible food pieces having a mean particle diameter of 1.0 mm to 10.0 mm.7. A method for producing a molded food product bound by a binder claim 1 , comprising the steps of:preparing a liquid raw material containing a koji-fermented grain liquid composition as the binder; anddehydrating said liquid raw material.8. The method according to claim 7 , wherein the liquid raw material is one selected from the group consisting of amazake claim 7 , sake cake claim 7 , and mixtures thereof.9. The method according to claim 7 , wherein the solid content of the liquid raw material is 35% or more by weight.10. The method according to claim 7 , wherein the addition rate of the binder is 30% or more by weight with respect to the solid content of the molded food product.11. The ...

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07-02-2019 дата публикации

FOOD-BASED PROTEIN FORMULATION

Номер: US20190037904A1
Принадлежит:

A food-based protein formulation includes a puree of one or more fruits and/or vegetables and protein. The source of the protein may be plant-based or animal based. Exemplary sources include whey protein and hydrolyzed collagen. The formulation may be packaged in 160 calorie servings. 1. A food-based protein formulation comprising:a puree of one or more fruits and/or vegetables;globular proteins; andhydrolyzed collagen or hydrolyzed gelatin.2. The food-based protein formulation of claim 1 , wherein the globular proteins are whey protein.3. The food-based protein formulation of claim 1 , wherein the food-based protein formulation is packaged such that the packaged food-based protein formulation provides at least 160 calories claim 1 , at least 20 g of protein claim 1 , and at least 20% of a recommended daily value of vitamins and minerals claim 1 , as recommended by the U.S. Food & Drug Administration.4. The food-based protein formulation of claim 3 , wherein the food-based protein formulation is packaged in a 5 fluid ounce flexible fitment pouch.5. The food-based protein formulation of claim 4 , wherein 4.5 fluid ounces of the food-based protein formulation is packaged in the 5 fluid ounce flexible fitment pouch.6. The food-based protein formulation of claim 1 , wherein the one or more fruits and/or vegetables are certified organic.7. The food-based protein formulation of claim 1 , wherein the globular proteins have a weight of between about 40% and about 60% as compared to the hydrolyzed collagen or hydrolyzed gelatin.8. A food-based protein formulation comprising:a puree of one or more fruits and/or vegetables; andprotein, wherein the puree and the protein are mixed and stored in a container having a volume of less than about 10 fluid ounces, and wherein the puree and the protein together provide at least 160 calories, at least 20 g of protein, and at least 20% of a recommended daily value of vitamins and minerals, as recommended by the U.S. Food & Drug ...

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07-02-2019 дата публикации

SNACKING PRODUCT WITH CAPSAICIN OR ANALOGUE THEREOF

Номер: US20190038577A1
Принадлежит: Altria Client Services LLC

A zero-calorie to near-zero-calorie snacking product that, when consumed, provides a feeling of fullness prior to absorption of energy-providing food, i.e., pre-absorptive satiation is disclosed. The snacking product is based on the stimulation of vagal nerve endings in the gastro-intestinal tract by encapsulated capsaicin. The encapsulation of capsaicin avoids the burning sensation in the mouth which may be objectionable to some consumers. 130-. (canceled)31. A snacking product comprising: a flavor system that comprises encapsulated capsaicin , an encapsulated capsaicin analogue , or a combination thereof; wherein the snacking product is a zero-calorie to near-zero calorie snacking product; wherein the snacking product does not comprise capsiate; and wherein the flavor system further comprises food fibers.32. The snacking product of claim 31 , wherein the snacking product is configured to stimulate vagal nerve endings in a gastrointestinal tract.33. The snacking product of claim 32 , wherein the vagal nerve endings express the transient receptor potential cation channel subfamily receptor V member 1 (TRPV1) receptor.34. The snacking product of claim 32 , wherein the vagal nerve endings express the cholecystokinin (CCK) receptor.35. The snacking product of claim 31 , wherein the encapsulated capsaicin claim 31 , encapsulated capsaicin analogue claim 31 , or combination thereof is micro-encapsulated.36. The snacking product of claim 31 , wherein the flavor system further comprises Korean Pine Oil.37. The snacking product of claim 31 , wherein the snacking product is an energy drink claim 31 , an energy bar claim 31 , a dietary supplement claim 31 , a capsule claim 31 , a pill claim 31 , a lozenge claim 31 , a sub-combination thereof or a combination thereof.38. The snacking product of claim 31 , wherein the snacking product is located in a screw cap of a beverage container.39. The snacking product of claim 38 , wherein the snacking product is released upon opening of ...

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06-02-2020 дата публикации

Nutritional Composition for Protecting Liver and Method for Preparing the Same

Номер: US20200037651A1
Автор: CI Zhonghua
Принадлежит:

The present application discloses a nutritional composition for protecting liver. The nutritional composition comprises the following components of raw materials in parts by weight: indica rice 60-83, polished round-grained rice 11-29, barbarum 1-4, finger citron 1.5-5, citron 0.05-0.2, and Chinese date 1-3.5. The present invention, in view of the liver's characteristics of preferring free activity and disliking depression, complies with the liver's physiological function characteristics for regulation, and provides the prescription based on the method of nourishing yin blood so as to disinhibit the liver, and it is suitable to cooperate with staple foods for long-term consumption, is easily accepted by people due to the good taste, and can achieve certain efficacies of soothing the liver and nourishing the liver. 1. A method for preparing a nutritional composition for protecting liver of claim 1 , wherein the method comprises the following steps in sequence:{'i': 'lycium', 'step 1, preparing raw materials: purifying and sorting indica rice, polished round-grained rice, barbarum, finger citron, citron, and Chinese date for subsequent use;'}step 2, frying: frying respective components of raw materials under a condition of 100-200° C. for 25-120 min;step 3, dosing: grinding the respective fried raw materials, then mixing and stirring evenly the respective ground raw materials according to proportions to obtain a rice powder;step 4, granulating: extruding the rice powder obtained in step 3 through a double-screw extruder, followed by gelatinization and granulation, to obtain mixed rice grains;step 5: drying: drying the mixed rice grains through a microwave dryer, wherein a water content of the material is kept below 12%, and cooling the dried mixed rice grains at a room temperature;step 6: sieving and packaging: sieving the cooled mixed rice grains, and vacuum-packaging the sieved mixed rice grains.2. The method for preparing a nutritional composition for protecting ...

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07-02-2019 дата публикации

NUTRITIONAL COMPOSITION

Номер: US20190038687A1
Автор: Hsia Houn Simon
Принадлежит:

The present invention provides nutritional compositions that are employed as oral supplementation to the human diet. The compositions of the present invention provide for supplementation to the diet of the cancer patient, as well as preventative dietary supplementation aimed at supporting the human immune system for those not currently suffering from cancer. The present invention is comprised of specific combinations of selected forms of unique sets of certain vitamins, minerals, protein, carbohydrates and phytochemicals. 1. An orally administrable nutritional composition comprising:selenium yeast;0.5 mg to 1.5 g fish oil, the fish oil having a combined EPA/DHA content of between 10% to 90% and an EPA/DHA ratio of between 1:5 and 5:1; and500 iu to 10,000 iu beta carotene;a milk protein;a rice protein; andinositol,wherein components of the nutritional composition are provided in amounts effective to both reduce cachectic symptoms and suppress neoplastic growth in the cancer patient when provided in combination.2. The nutritional composition of claim 1 , wherein the selenium yeast is in an amount from 10 μg to 250 μg.3. The nutritional composition of claim 1 , wherein the selenium yeast is in an amount from 25 μg to 1500 μg.4Saccharomyces cerevisiae, Saccharomyces exiguous, Saccharomyces pastorianus, Saccharomyces boulardii, Saccharomyces bayanus, Saccharomyces eubayanus, Saccharomyces florentinusSaccharomyces fragilis.. The nutritional composition of claim 1 , wherein the selenium yeast is one or more of the group consisting of: claim 1 , and5. The nutritional composition of claim 1 , wherein the fish oil has an EPA/DHA content of between 30% to 70%.6. The nutritional composition of claim 1 , wherein the fish oil has an EPA/DHA content of between 40% to 60%.7. The nutritional composition of claim 1 , wherein the fish oil has an EPA/DHA ratio of about 2:1.8. The nutritional composition of claim 1 , wherein the fish oil has an EPA/DHA ratio of about 3:2.9. The ...

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18-02-2021 дата публикации

COCOA-BASED FOOD PRODUCTS

Номер: US20210045405A1
Автор: Petyaev Ivan
Принадлежит:

The invention is concerned with food products comprising one or more cocoa bean products and a carotenoid compound, particularly with food products which are, or comprise, chocolate. The products of the invention may be used in reducing elevated total cholesterol, triglycerides and inflammatory damage, as well as improving tissue microcirculation and tissue oxygenation. 2. The method of claim 1 , wherein the food product is chocolate or another food product containing cocoa solid claim 1 , cocoa butter claim 1 , cocoa liquor and/or their derivatives.3. The method of claim 1 , wherein the method(a) reduces postprandial cholesterol and triglyceride-aemias;(b) reduces size of chylomicrons and increases their rate of their clearance;(c) increases plasma molecular oxygen transport, microcirculation and tissue oxygen saturation;(d) reduces postprandial inflammatory and oxidative stress; and/or(e) reduces postprandial or other liver (micro-) damage and liver steatosis.4. The method of claim 1 , wherein said individual is overweight (has a BMI over 25) or obese (has a BMI over 30).5. The method of claim 1 , wherein the method comprises reducing claim 1 , delaying or masking the visual signs of ageing.6. The method of claim 1 , wherein the individual is mature or elderly.7. The method of claim 1 , wherein the skin condition is acne claim 1 , chronic skin ulcerations claim 1 , skin or tissue burns or other age or non-age related skin conditions.8. The method of claim 1 , wherein said individual has a condition selected from cerebro-vascular disorder claim 1 , cardio-vascular disorder claim 1 , hypertension claim 1 , metabolic syndrome claim 1 , high blood pressure claim 1 , pre-diabetes claim 1 , type II diabetes claim 1 , anaemia claim 1 , rheumatism claim 1 , rheumatoid arthritis claim 1 , non-rheumatoid arthritis claim 1 , prostate or testes malfunction claim 1 , erectile dysfunction claim 1 , loss of libido claim 1 , cellulite claim 1 , sarcopenia and cachexia.9. The ...

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07-02-2019 дата публикации

High-Purity Steviol Glycosides

Номер: US20190040434A1
Принадлежит:

Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2 and reb M2 are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums. 1. A method for producing target steviol glycosides , comprising the steps of:a. providing a starting composition comprising an organic compound with at least one carbon atom;b. providing a microorganism or a biocatalyst containing at least one enzyme selected from steviol biosynthesis enzymes, UDP-glycosyltransferases, and optionally providing UDP-glucose recycling enzymes;c. contacting the microorganism with a medium containing the starting composition to produce a medium comprising at least one target steviol glycoside.2. The method of claim 1 , further comprising the step of:d. purifying the target steviol glycoside from the medium to provide a highly purified target steviol glycoside composition.3. The method of claim 1 , wherein the organic compound is selected from the group consisting of polyols claim 1 , carbohydrates claim 1 , steviol glycosides and combinations thereof.4. The method of claim 1 , wherein the biocatalyst is an enzyme claim 1 , or a cell comprising one or more enzymes claim 1 , capable of converting the organic compound to target steviol glycoside.5. The method of claim 1 , wherein the target steviol glycoside is selected from the group consisting of stevioside claim 1 , reb A claim 1 , reb D claim 1 , reb D2 claim 1 , reb E claim 1 , reb M claim 1 , reb M2 and mixtures thereof.6. The method of claim 1 , wherein the enzyme is selected from the group consisting of geranylgeranyl diphosphate synthase claim 1 , ...

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15-02-2018 дата публикации

COMPOSITIONS CONTAINING NON-POLAR COMPOUNDS

Номер: US20180042865A1
Автор: Bromley Philip J.
Принадлежит:

Provided herein are compositions and methods for preparing foods and beverages that contain additives, such as nutraceuticals, pharmaceuticals, and supplements, such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives. 1. A liquid nanoemulsion concentrate , comprising:a non-polar active ingredient;a tocopherol polyethylene glycol succinate (TPGS) surfactant; anda polar solvent, wherein:the amount of non-polar active ingredient is between about 5% and about 10%, by weight, of the concentrate;the amount of TPGS surfactant is between 16% or about 16% and 30% or about 30%, by weight, of the concentrate;the amount of polar solvent is between about 60% and about 80%, by weight, of the concentrate; andthe non-polar active ingredient is not TPGS.2. The liquid nanoemulsion concentrate of claim 1 , wherein the non-polar active ingredient is selected from among any one or more of polyunsaturated fatty acids claim 1 , Coenzyme Q10 compounds and phytosterols.3. The liquid nanoemulsion concentrate of claim 1 , wherein the non-polar active ingredient is one or more polyunsaturated fatty acids.4. The liquid nanoemulsion concentrate of claim 1 , wherein the non-polar active ingredient contains at least one polyunsaturated fatty acid selected from among omega-3 fatty acids claim 1 , omega-6 fatty acids claim 1 , and conjugated fatty acids.5. The liquid nanoemulsion concentrate of claim 4 , wherein the non-polar active ingredient contains a polyunsaturated fatty acid selected from among a docosahexaenoic acid (DHA) claim 4 , an eicosapentaenoic acid (EPA) claim 4 , a fish oil claim 4 , a flaxseed oil claim 4 , a borage oil claim 4 , an alpha-linolenic acid (ALA) claim 4 , a gamma-linolenic acid (GLA) claim 4 , a conjugated linoleic acid (CLA) claim 4 , and a saw palmetto extract.6. The liquid ...

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14-02-2019 дата публикации

ROSEMARY/PHOSPHOLIPASE COMPOSITIONS AND METHODS OF PRESERVING MUSCLE TISSUE

Номер: US20190045803A1
Принадлежит: WISCONSIN ALUMNI RESEARCH FOUNDATION

The disclosure provides for compositions and methods for the preservation of meat tissues, including fish, beef, poultry and pork, and meat analogs containing added heme protein, using very low amounts of phospholipase A2 (PLA2) enzymes in a combination with rosemary. 1. A method of improving storage life of (a) comminuted or intact muscle tissue or (b) meat analog containing added heme protein , comprising contacting said tissue with about 50 U/kg to about 500 U/kg phospholipase A2 enzyme (PLA2) and rosemary extract at about 150 ppm to about 525 ppm.2. The method of claim 1 , wherein said rosemary extract iscontacted at a concentration of about 150 ppm.35-. (canceled)6. The method of claim 1 , wherein said rosemary extract is contacted at a concentration of no more than about 250 ppm.7. The method of claim 1 , wherein said rosemary extract is contacted at a concentration of about 175 ppm to about 225 ppm.810-. (canceled)11. The method of claim 1 , wherein said rosemary extract is contacted at a concentration of PM about 200 ppm.12. The method of claim 1 , wherein said PLA2 enzyme is contacted at a concentration of about 50 U/kg.1315-. (canceled)16. The method of claim 1 , wherein said PLA2 enzyme is contacted at a concentration of no more than about 525 U/kg.17. The method of claim 1 , wherein said PLA2 enzyme is contacted at a concentration of about 63 U/kg to about 450 U/kg.1820-. (canceled)21. The method of claim 1 , wherein said PLA2 enzyme is contacted at a concentration of about 250 U/kg.22. The method of claim 1 , wherein said muscle tissue is avian tissue claim 1 , fish claim 1 , shellfish claim 1 , reptile tissue or amphibian tissue.23. (canceled)24. The method of claim 1 , wherein said tissue is mammalian tissue.25. The method of claim 1 , wherein said tissue is red meat.2628-. (canceled)29. The method of claim 1 , wherein said muscle tissue is cooked or cured muscle tissue.30. The method of claim 1 , wherein said muscle tissue is uncooked and uncured.31. ...

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14-02-2019 дата публикации

COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE

Номер: US20190046469A1
Автор: KUHRTS Eric Hauser
Принадлежит:

Methods for the treatment of mood disorders and/or skin disease or damage (eczema, atopic dermatitis, or wrinkles, for example) can comprise administering an extracted prenylflavonoid to a subject experience the mood disorder or the skin disease or damage. 1. A method of treating a mood disorder , skin disease , or skin damage , comprising administering a formulation comprising an extracted prenylflavonoid in an amount sufficient to activate oxytocin related genes to and increase oxytocin levels in a subject suffering from an oxytocin responsive mood disorder , skin disease , or skin damage.2. The method of claim 1 , wherein the prenylflavonoid is selected from the group comprising xanthohumol claim 1 , xanthogalenol claim 1 , desmethylxanthohumol (2′ claim 1 ,4′ claim 1 ,6′ claim 1 ,4-tetrahydrooxy-3-C-prenylchalcone) claim 1 , 2′ claim 1 ,4′ claim 1 ,6′ claim 1 ,4-tetrahydrooxy-3′-C-geranylchalcone claim 1 , dehydrocycloxanthohumol claim 1 , dehydrocycloxanthohumol hydrate claim 1 , 5′-prenylxanthohumol claim 1 , tetrahydroxanthohumol claim 1 , 4′-O-5′-C-diprenylxanthohumol claim 1 , chalconaringenin claim 1 , isoxanthohumol claim 1 , 6-prenylnaringenin claim 1 , 8-prenylnaringenin claim 1 , 6 claim 1 ,8-diprenylnaringenin claim 1 , 4′ claim 1 ,6′-dimethoxy-2′ claim 1 ,4-dihydroxychalcone claim 1 , 4′-O-methylxanthohumol claim 1 , 6-geranylnaringenin claim 1 , 8-geranylnaringenin claim 1 , their metabolites claim 1 , their derivatives claim 1 , and any combination thereof.3. The method of claim 1 , wherein the prenylflavonoid is xanthohumol.4. The method of claim 3 , wherein the xanthohumol is present at a concentration from about 0.01% to 50% by weight.5. The method of claim 1 , wherein the formulation further comprises a non-ionic surfactant.6. The formulation of claim 5 , wherein the non-ionic surfactant is selected from the group consisting of non-ionic water soluble mono- claim 5 , di- claim 5 , or tri-glycerides; non-ionic water soluble mono- or di-fatty ...

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14-02-2019 дата публикации

Compositions with specific oligosaccharides to prevent later in life obesity or related comorbidities, by increasing colonic scfa production and/or by increasing glp-1 secretion

Номер: US20190046545A1
Принадлежит: Nestec SA

The present invention relates to a nutritional composition comprising an oligosaccharide mixture, said oligosaccharide mixture comprising at least one N-acetylated oligosaccharide, one galacto-oligosaccharide and one sialylated oligosaccharide for use in reducing and/or avoiding excessive fat mass accumulation and/or in preventing any related later in life health disorders in an infant or a young child such as later in life obesity and related comorbidities, by increasing colonic SCFA production and/or GLP-1 secretion/releasein said infant or young child.

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22-02-2018 дата публикации

Sweetener composition and food containing same

Номер: US20180049455A1
Принадлежит: Morita Kagaku Kogyo Co Ltd

The present invention provides a sweetener composition that can be used for food as a sugar substitute sweetener. Specifically, the sweetener composition contains rebaudioside O and rebaudioside N as active ingredients, or contains at least one of rebaudioside D and rebaudioside M and at least one of rebaudioside O and rebaudioside N as active ingredients. In addition, the sweetener composition is used in combination with an additional sweetener.

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14-02-2019 дата публикации

NATURAL EQUIVALENT OF CHEMICALLY MODIFIED STARCH

Номер: US20190048170A1
Принадлежит: Cargill, Incorporated

The present invention relates to a composition comprising citrus fruit fiber having a water binding capacity of from 8 to 25 (w/w) and native starch selected from the group consisting of corn starch, rice flour, sorghum starch, tapioca starch and mixture thereof. 1. A composition suitable to substitute chemically modified starch comprising: citrus fruit fiber having a water binding capacity of from 7 to 25 grams of water per gram of fiber; and native starch selected from the group consisting of corn starch , rice flour , sorghum starch , tapioca starch , waxy wheat flour , amylase free potato starch and mixture thereof2. A composition according to characterized in that the weight ratio citrus fruit fiber to native starch is between 1:5 and 1:1.3. A composition according to characterized in that the citrus fruit fiber is obtainable from citrus fruit selected from the group consisting of oranges claim 1 , tangerines claim 1 , limes claim 1 , lemons claim 1 , and grapefruit.4. A composition according to characterized in that the citrus fruit fiber has a total dietary fiber content of from 60 to 85-wt %.5. A composition according to characterized in that the citrus fruit fiber comprises from 8 to 12% (w/w) proteins.6. A composition according to characterized in that the native starch is a waxy starch.7. A composition according to characterized in that the native starch is glutinous rice flour.8. A composition according to characterized in that it further comprises edible additives.9. A composition according to to characterized in that the further edible additive is selected from xanthan gum claim 8 , guar gum claim 8 , pectin claim 8 , carrageenan claim 8 , fiber claim 8 , soy protein and mixtures thereof.10. A composition according to characterized in that the further edible additive is xanthan gum.11. (canceled)12. (canceled)13. Use of the composition according to in food applications claim 1 , feed applications claim 1 , pharma products or cosmetics.14. Beverage ...

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25-02-2021 дата публикации

Novel salmonella typhimurium bacteriophage stp-2 and use thereof for inhibiting proliferation of salmonella typhimurium

Номер: US20210054345A1
Принадлежит: Intron Biotechnology Inc

The present invention relates to a Siphoviridae bacteriophage STP-2 (Accession number: KCTC 12853BP) isolated from nature and characterized by having the ability to destroy Salmonella Typhimurium and having a genome represented by SEQ ID NO:1; and to a method for preventing and treating diseases caused by Salmonella Typhimurium using Siphoviridae bacteriophage STP-2 containing the same as an active ingredient.

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25-02-2021 дата публикации

Nano-vesicles derived from genus morganella bacteria and use thereof

Номер: US20210054412A1
Автор: Yoon-Keun Kim
Принадлежит: MD Healthcare Inc

The present invention relates to vesicles derived from genus Morganella bacteria and a use thereof, the present inventors experimentally confirmed that the vesicles were significantly decreased in clinical samples derived from patients with a malignant disease such as gastric cancer, colorectal cancer, pancreatic cancer, bile duct cancer, breast cancer, ovarian cancer, bladder cancer, prostate cancer and lymphoma, a cardiovascular disease such as myocardial infarction, cardiomyopathy, atrial fibrillation, variant angina, and stroke, diabetes mellitus, and Parkinson's disease as compared to normal persons, and the vesicles suppressed the secretion of inflammatory mediators by pathogenic vesicles and suppressed the occurrence of cancer, so that the vesicles derived from genus Morganella bacteria may be usefully used for the purpose of developing a method for diagnosing a malignant disease such as gastric cancer, colorectal cancer, pancreatic cancer, bile duct cancer, breast cancer, ovarian cancer, bladder cancer, prostate cancer and lymphoma, a cardiovascular disease such as myocardial infarction, cardiomyopathy, atrial fibrillation, variant angina, and stroke, diabetes mellitus, and Parkinson's disease, and a composition for preventing or treating the diseases or an inflammatory disease

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10-03-2022 дата публикации

COMPOSITIONS AND METHODS RELATED TO ANIONIC CANNABINOID MOLECULES

Номер: US20220071256A1
Автор: Metcalf Douglas G.
Принадлежит:

This patent document discloses compositions and methods related to anionic cannabinoid molecules that contain oxide substituents. 143-. (canceled)44. A container , comprising a sealed chamber , in which:the container contains a composition in the sealed chamber;the composition comprises water and an anionic cannabinoid molecule; andthe anionic cannabinoid molecule is dissolved in the water.4585-. (canceled)86. The composition of claim 99 , wherein the composition is a liquid claim 99 , the composition has a pH claim 99 , and the pH of the composition is 7 to 13.87. The composition of claim 99 , wherein the pH of the composition is 8 to 10.88. The composition of claim 99 , comprising the anionic cannabinoid molecule and the cannabinoid molecule at a molar ratio of 1:10 to 10 claim 99 ,000:1.89. The composition of claim 99 , comprising the anionic cannabinoid molecule and the cannabinoid molecule at a molar ratio of 1:1 to 100:1.90. The composition of claim 99 , comprising water.91. The composition of claim 99 , comprising water at a concentration by weight of 50 percent to 99.99 percent.92. The composition of claim 99 , comprising ethanol.93. The composition of claim 92 , comprising ethanol at a concentration by weight of 50 parts per million to 2 percent.94. The composition of claim 92 , comprising ethanol at a concentration by weight of 1 percent to 20 percent.95. The composition of claim 92 , comprising ethanol at a concentration by weight of 10 percent to 95 percent.96. The composition of claim 99 , comprising the anionic cannabinoid molecule at a concentration of 1 milligram per liter to 100 milligrams per liter.97. The composition of claim 99 , comprising the anionic cannabinoid molecule at a concentration of 50 milligrams per liter to 5 grams per liter.98. The composition of claim 99 , comprising the anionic cannabinoid molecule at a concentration of 2 grams per liter to 200 grams per liter.99. A composition claim 99 , comprising an anionic cannabinoid ...

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01-03-2018 дата публикации

NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF

Номер: US20180055864A1
Принадлежит: ABBOTT LABORATORIES

Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases. 1. A synthetic pediatric formula comprising a human milk oligosaccharide and from about 0.025 mM to about 1 mM of a long chain polyunsaturated fatty acid.2. The synthetic pediatric formula of claim 1 , wherein the human milk oligosaccharide is selected from the group consisting of 6′-sialyllactose claim 1 , 3′-sialyllactose claim 1 , 2′-fucosyllactose claim 1 , 3-fucosyllactose claim 1 , lacto-N-tetraose claim 1 , lacto-N-neotetraose claim 1 , lacto-N-fucopentaose claim 1 , and combinations thereof.3. The synthetic pediatric formula of claim 1 , wherein the human milk oligosaccharide is present in an amount of from about 0.001 mg/mL to about 20 mg/mL and is selected from the group consisting of 6′-sialyllactose claim 1 , 3′-sialyllactose claim 1 , 2′-fucosyllactose claim 1 , lacto-N-neotetraose claim 1 , and combinations thereof.4. The synthetic pediatric formula of claim 1 , wherein the long chain polyunsaturated fatty acid is selected from the group consisting of linoleic acid claim 1 , linolenic acid claim 1 , arachidonic acid claim 1 , docosahexaenoic acid claim 1 , eicosapentaenoic acid claim 1 , docosapentaenoic acid claim 1 , and combinations thereof.5. The synthetic pediatric formula of claim 1 , wherein the long chain polyunsaturated fatty acid is arachidonic acid claim 1 , docosahexaenoic acid claim 1 , or a combination of both.6. The synthetic pediatric formula of claim 1 , wherein the human milk oligosaccharide is 6′-sialyllactose.7. The synthetic pediatric formula of claim 6 , wherein the 6′-sialyllactose is present in a concentration of from about 0.001 mg/mL to about 20 mg/mL.8. The synthetic pediatric formula of claim 1 , wherein the human milk ...

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01-03-2018 дата публикации

Composition Comprising Neoagarooligosaccharide As Active Ingredient, For Prevention or Treatment of Sepsis or Septic Shock

Номер: US20180055872A1
Принадлежит:

The present invention relates to a composition for prevention or treatment of sepsis or septic shock, in which the composition includes neoagarooligosaccharide as an active ingredient, and the neoagarooligosaccharide according to the present invention has an excellent effect in terms of immune enhancement by effectively suppressing inflammation, and also exhibits a good effect in preventing sepsis, and therefore can be effectively used in pharmaceuticals and functional foods for prevention or treatment of sepsis or septic shock and immune enhancement. 1. A pharmaceutical composition for prevention or treatment of sepsis or septic shock , the pharmaceutical composition comprising neoagarooligosaccharide , which is prepared from agar or agarose by a DagA enzyme reaction , as an active ingredient.2Streptomyces coelicolor.. The pharmaceutical composition of claim 1 , wherein the DagA enzyme is derived from3. The pharmaceutical composition of claim 2 , wherein the DagA enzyme is represented by amino acid sequences 31 to 309 of SEQ ID NO: 2.4. The pharmaceutical composition of claim 2 , wherein the DagA enzyme is encoded by a nucleotide sequence of SEQ ID NO: 1.5. The pharmaceutical composition of claim 1 , wherein the enzyme reaction is carried out at a temperature of 35° C. to 45° C. and pH of 6 to 8.6. The pharmaceutical composition of claim 1 , wherein the neoagarooligosaccharide is one or more kinds selected from the group consisting of neoagarobiose claim 1 , neoagarotetraose claim 1 , and neoagarohexaose.7. A food composition for prevention or ameliorating sepsis or septic shock claim 1 , the food composition comprising neoagarooligosaccharide prepared from agar or agarose by DagA enzyme reaction as an active ingredient.8. A pharmaceutical composition for reinforcement of immunization claim 1 , the pharmaceutical composition comprising neoagarooligosaccharide prepared from agar or agarose by a DagA enzyme reaction claim 1 , as an active ingredient.9. A functional ...

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04-03-2021 дата публикации

Powderous composition comprising carotenoid and/or derivative thereof, d-glycose oligomers and modified polysaccharide as well as food, feed or personal care formulation comprising the composition

Номер: US20210059283A1
Принадлежит: DSM IP ASSETS BV

The invention relates a powderous composition, which can be produced easily and which can be used in many fields of application. The claims are directed to a powderous composition comprising (i) up to 70 weight-% (wt-%), based on the total weight of the powderous composition, of at least one carotenoid and/or one carotenoid derivative, and (ii) 5-30 wt-%, based on the total weight of the powderous composition, of at least one D-glycose oligomer (preferably a maltodextrin) (G01) having a DE of <18, and (iii) 5-30 wt-%, based on the total weight of the powderous composition, of at least one D-glycose oligomer (preferably a maltodextrin) (G02) having a DE of >18, and (iv) 5-70 wt-%, based on the total weight of the powderous composition, of at least one modified polysaccharide, as well as to a food, feed or personal care formulation comprising at least one powderous composition.

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04-03-2021 дата публикации

Bioreactor system for the cultivation of filamentous fungal biomass

Номер: US20210059287A1
Принадлежит:

A one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium is provided. 130-. (canceled)31. A method of producing a filamentous fungal biomass , comprising:placing a feedstock and a porous membrane in a container;inoculating the feedstock with a fungal inoculum;incubating the feedstock and fungal inoculum in the container to form a filamentous fungal biomass on the porous membrane.32. The method of producing a filamentous fungal biomass of claim 31 , wherein the feedstock is inoculated with the fungal inoculum before the feedstock is placed in the container.33. The method of producing a filamentous fungal biomass of claim 31 , wherein the feedstock is inoculated with the fungal inoculum after the feedstock is placed in the container.34. The method of producing a filamentous fungal biomass of claim 31 , further comprising harvesting the filamentous fungal biomass by removing it from the porous membrane.35. The method of producing a filamentous fungal biomass of claim 31 , wherein the container comprises a cover.36. The method of producing a filamentous fungal biomass of claim 31 , wherein the porous membrane has a pore size of the greater than 0.05 μm.37. The method of producing a filamentous fungal biomass of claim 31 , wherein the porous membrane is selected from the group consisting of cloth-like material and paper-like material.38. The method of producing a filamentous fungal biomass of claim 31 , wherein the porous membrane comprises a polymeric material.39. The method of producing a filamentous fungal biomass of claim 31 , wherein the porous membrane comprises a polymeric material selected from the group consisting of polypropylene claim 31 , polyethylene claim 31 , polytetrafluorethylene claim 31 , polycarbonate claim 31 , polyamide claim 31 , polypyrrolone claim ...

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21-02-2019 дата публикации

PLANT OR MICROORGANISM-DERIVED CAROTENOID-OXYGEN COPOLYMER COMPOSITIONS, METHODS OF IDENTIFYING, QUANTIFYING AND PRODUCING SAME AND USES THEREOF

Номер: US20190054135A1
Принадлежит:

The present invention relates to carotenoid-oxygen copolymers, compositions, methods of identifying and quantifying carotenoid-oxygen copolymers in food and related sources, and methods of producing compositions comprising same. In one aspect the method of identifying and quantifying carotenoid-oxygen copolymers comprises an analysis of a low molecular weight marker compound in said sources. In another aspect the present invention provides a method of preparing compositions comprising said carotenoid-oxygen copolymers and/or enhancing levels of said copolymers in food sources in a sufficient and practically useful concentration to have beneficial effects in animals and humans, including beneficial immunological and health effects. 1. A method of identifying a source of carotenoid-oxygen copolymer comprising:(a) selecting a food plant source or microorganism source containing carotenoids;(b) processing the source under oxidative polymerization conditions; and(c) quantifying the amount of carotenoid-oxygen copolymer by directly isolating or identifying same from said processed source and/or by isolating or identifying an indicator of same from said processed source, to determine whether it is a source of carotenoid-oxygen copolymer.2. The method of claim 1 , wherein the sources have a starting amount of carotenoid claim 1 , which may provide upon oxidation the same amount of carotenoid-oxygen copolymer of 1-1000 μg/g wet weight or 10-10 claim 1 ,000 μg/g dry weight.3. The method of or claim 1 , wherein the oxidative polymerization conditions are selected from exposure to air or oxygen and one or more of drying claim 1 , powdering claim 1 , increasing exposure to heat claim 1 , light claim 1 , increasing the partial pressure of oxygen (ppO) or other factors that promote oxidation.4. The method of any one of - wherein the isolation of carotenoid-oxygen copolymer comprises at least one polar organic solvent extraction/non-polar solvent precipitation cycles.5. The method ...

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28-02-2019 дата публикации

METHODS FOR TREATING A DIVIDED CHEESE PRODUCT AND COMPOSITIONS THEREOF

Номер: US20190059407A1
Принадлежит:

Disclosed herein is an anticaking agent for cheese, comprising one or more dairy ingredients; and one or more non-dairy ingredients. When applied the anticaking agent is applied to a divided cheese, it has low visibility on the divided cheese, prevents caking of the divided cheese, and browns similarly to divided cheese without the anticaking agent when baked in an impinger oven at between 425° F. and 450° F. for 5 minutes. Also disclosed are food products containing an anticaking agent described herein, and methods for treating divided cheese for anticaking using an anticaking agent described herein. 1. An anticaking agent for cheese , comprising:20-70 wt. % one or more dairy ingredients; and30-80 wt. % one or more non-dairy ingredients;wherein the anticaking agent when applied to a divided cheese has low visibility on the divided cheese, prevents caking of the divided cheese, and browns similarly to divided cheese without the anticaking agent when baked in an impinger oven at between 425° F. and 450° F. for 5 minutes.2. The anticaking agent of claim 1 , wherein the one or more dairy ingredient is chosen from dairy product solids claim 1 , milk permeate powder claim 1 , whey permeate powder claim 1 , cheese whey powder claim 1 , sweet dairy whey powder claim 1 , non-hygroscopic dried whey claim 1 , whey powder claim 1 , whey protein concentrate claim 1 , whey protein isolate claim 1 , milk protein concentrate claim 1 , milk protein isolate claim 1 , whey cream claim 1 , whey protein-lipid concentrate claim 1 , rennet casein claim 1 , calcium caseinate claim 1 , sodium caseinate claim 1 , milk minerals claim 1 , milk calcium claim 1 , milk calcium phosphate claim 1 , lactose claim 1 , skim milk powder claim 1 , non-fat dry milk claim 1 , acid casein claim 1 , and combinations thereof.3. The anticaking agent of claim 2 , wherein the one or more dairy ingredient is chosen from milk permeate powder claim 2 , whey permeate powder claim 2 , deproteinized whey claim 2 , ...

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28-02-2019 дата публикации

ANIMAL FEED

Номер: US20190059426A1
Автор: Majkrzak Robert
Принадлежит:

An animal feed product disclosed herein has a feed mixture disposed in a container, where the feed mixture has a plurality of animal feed particles and seed butter coating each of the animal feed particles. A removable cover is coupled to the container over the cavity to encase the feed mixture. A method disclosed herein relates to heating a seed butter to reduce its viscosity. Animal feed particles are translated through a spraying region and each of the animal feed particles are coated with the heated seed butter to form a seed mixture. The seed mixture is deposited in a container defining a cavity and the feed mixture is compressed in the cavity. Other embodiments are described. 1. An animal feed product comprising:a container defining a cavity; a plurality of animal feed particles comprising a plurality of seeds; and', 'seed butter coating each of the plurality of animal feed particles, wherein the seed butter is no more than 20% of the feed mixture by weight; and, 'a feed mixture disposed in the cavity, the feed mixture comprisinga removable cover coupled to the container over the cavity, wherein the removable cover and the container encase the feed mixture.2. The animal feed product of claim 1 , wherein the animal feed particles further comprises at least one in the group consisting of: a plurality of dehydrated invertebrates and a plurality of dehydrated insects.3. The animal feed product of claim 2 , wherein the plurality of dehydrated invertebrates comprises at least one in the group consisting of: mealworms and black soldier fly larvae.4. The animal feed product of claim 1 , wherein the plurality of seeds comprise at least one type of seed in the group consisting of: sunflower claim 1 , grain claim 1 , legume claim 1 , and grass.5. The animal feed product of claim 1 , wherein the seed butter comprises sunflower seed butter.6. The animal feed product of claim 1 , wherein the seed butter contains at least one type of seed in the group consisting of: peanuts ...

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28-02-2019 дата публикации

ALL PURPOSE SEASONING SAUCE

Номер: US20190059427A1
Автор: Allen Brenda
Принадлежит:

A flavoring condiment sauce for food comprised of about 19%-21% lemon juice, about 19%-21% water, about 12%-14% minced garlic, about 12%-14% butter or margarine, about 12%-14% onion, about 0.15%-0.5% Abodo sauce, about 2%-3% garlic powder, about 0.15%-0.5% seasoning salt, about 6%-8% black pepper, about 1%-2% crushed red pepper, and about 8%-10% Accent salt. 1. A flavoring condiment sauce for food , comprising:about 19%-21% lemon juice;about 19%-21% water;about 12%-14% minced garlic;about 12%-14% butter or margarine;about 12%-14% onion;about 0.15%-0.5% Abodo sauce;about 2%-3% garlic powder;about 0.15%-0.5% seasoning salt;about 6%-8% black pepper;about 1%-2% crushed red pepper; andabout 8%-10% Accent salt.2. The flavoring condiment sauce of claim 1 , further comprising between about 2%-21% chopped crab.3. A method of preparing the ingredients in into a flavoring sauce claim 1 , comprising the steps of:in a container, mixing together lemon juice, water, butter/margarine, and onions;heating the container to a medium boil;adding remainder of ingredients to the heated container;continuing cooking on a medium boil for 15 to 20 minutes or until sauce thickens to a salad-dressing-like consistency;removing heat;allowing sauce to cool to room temperature (80° to 72° F.);packaging sauce into a resealable container; andrefrigerating to at least 40° F.4. A method of preparing a flavoring sauce claim 1 , comprising the steps of:providing a container;mixing together lemon juice, water, butter/margarine, and onions and adding to the container;heating the container to a medium boil;adding remainder of ingredients to the heated container;continuing cooking on a medium boil for 15 to 20 minutes or until sauce thickens to a salad-dressing-like consistency;removing heat from the container;allowing sauce to cool to room temperature;packaging sauce into a resealable container; andrefrigerating the packaged sauce.5. The method of preparing a flavoring sauce of claim 4 , wherein the ...

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28-02-2019 дата публикации

EDIBLE FOODSTUFFS AND BIO REACTOR DESIGN

Номер: US20190059431A1
Принадлежит:

Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. 1. A formulation of edible filamentous fungi comprising edible filamentous fungal particles , wherein the edible filamentous fungal particles comprise unbroken filamentous fungal filaments , broken filamentous fungal filaments , or combinations thereof , wherein the edible fungal particles are isolated from edible filamentous fungus biomats.2Fusarium oxysporum. The formulation of claim 1 , wherein the filamentous fungus is strain MK7 (ATCC Accession Deposit No. PTA-10698).3Agaricus bisporusBoletus edulisCantarellus cibariusCalvatia giganteaCyclocybe aegeritaGanoderma lucidumGrifola frondosaMorchellaHypsizygus tessellatusHypsizygus ulmariusLaetiporusLentinula edodesPleurotus eryngiiPleurotus ostreatusPholiota microsporaSparassis crispaTuber. The formulation of claim 1 , wherein the filamentous fungus is selected from the group consisting of (crimini and white) claim 1 , (porcinini) claim 1 , (chantrelle) claim 1 , (giant puffball) claim 1 , (velvet piopinni) claim 1 , (Reishi) claim 1 , (maitake) claim 1 , species (Morel) claim 1 , (clamshell) claim 1 , (elm oyster) claim 1 , species (chicken of the woods) claim 1 , (shiitake) claim 1 , (trumpet royale) claim 1 , (pearl oyster and blue oyster) claim 1 , (forest nameko) claim 1 , (cauliflower) claim 1 , and species (truffles).4. The formulation of claim 1 , wherein the formulation is a liquid.5. The formulation of claim 1 , wherein the formulation is a solid.6. The formulation of claim 1 , wherein the formulation is a paste claim 1 , a flour claim 1 , an aerated mass or a firm mass.7. A foodstuff ...

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28-02-2019 дата публикации

ORAL REHYDRATION COMPOSITION AND METHODS THEREOF

Номер: US20190059434A1
Принадлежит:

An oral rehydration composition comprising the following: 1-glutamic acid in a range of about 0.01% to about 0.40% w/w and monosodium glutamate in a range of about 0.05% to about 0.80% w/w; about 1.50% w/w glucose monohydrate; about 0.20% w/w sodium chloride; about 0.15% w/w potassium chloride; about 0.35% w/w glycine; about 0.30% w/w trisodiumcitrate; about 0.15% w/w sodium dihydrogen phosphate; about 0.10% w/w xanthan gum; 85% Steviol Glycoside extract in a range of about 0.01% to about 0.03% w/w; about 0.20% w/w citric acid monohydrate; hydrolyzed whey in a range of about 0.15% to about 1.00% w/w; about 1.00% w/w hydrolyzed wheat; comprises cereals as a protein source; comprises enzyme co-factors; comprises a monosaccharide. The oral rehydration composition can be used on humans or animals that suffer from diarrhea. 1. A method of preventing dehydration comprising the steps of:a. preparing an oral rehydration composition;b. administering said oral rehydration composition to the individual;wherein said composition comprises ingredients selected from the group consisting of: water, glucose monohydrate, sodium chloride, potassium chloride, glycine, sodium dihydrogen phosphate, xantham gum, citric acid monohydrate, hydrolyzed whey protein, steviol glycoside extract, 1-glutamic acid, monosodium glutamate, and any combination thereof.2. The method of claim 1 , wherein said individual is a human.3. The method of claim 1 , wherein said individual is an animal.4. The method of claim 1 , wherein said subject is suffering from diarrhea. This application is a divisional of U.S. application Ser. No. 15/527,724 filed May 18, 2017 which is a U.S. National Phase filing under 35 U.S.C. 371 of International (PCT) Patent Application No. PCT/IB2015/058699, filed 11 Nov. 2015, which claims priority from U.S. Patent Application No. 62/081,588, filed 19 Nov. 2014, all of which are incorporated by referenced in their entirety.This invention relates to oral rehydration products for the ...

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28-02-2019 дата публикации

ORAL LIPID SUPPLEMENTS FOR TREATING PAIN AND FIBROMYALGIA

Номер: US20190060335A1
Автор: Settineri Robert A.
Принадлежит:

A method of oral delivery of phospholipid/inulin compositions comprising capsules, tablets, chewable wafers or powdered material in a liquid carrier in quantities effective for treating systemic pain from fibromyalgia. The compositions further including effective amounts of caffeine also reduces fatigue and enhances alertness and focus. 2. The method of wherein an effective unit dose comprises at least about 1 g of the phospholipids.3. The method of wherein an effective daily dosage is 4 g of the phospholipids claim 2 , said daily dosage comprising four unit dosages delivered approximately every 6 hours over a 24-hour period.4. The method of wherein the daily dosage is delivered for about 14 days.5. The method of wherein the unit dosage also includes an amount of caffeine effective to reduce fatigue and enhance alertness and/or focus.6. The method of wherein an effective unit dose comprises at least 1.2 g of the phospholipids.7. The method of wherein an effective daily dosage is 4.8 g of the phospholipids claim 6 , said daily dosage comprising four unit dosages delivered approximately every 6 hours over a 24-hour period.8. The method of wherein the phospholipids comprises about 19-29% phosphatidylcholine (PC) claim 1 , 15-25% phosphatidylethanolamine (PE) claim 1 , 3.5%-10% phosphatidic acid (PA) claim 1 , 10-18% phosphatidylinositol (PI) claim 1 , 2-10% claim 1 , phosphatidylglycerol (PG) claim 1 , 10-20% glycolipids and phosphatidylserine (PS).10. The method of wherein an effective unit dose comprises about 1 g of the phospholipids and about 1 gm of caffeine.11. The method of wherein an effective unit dose comprises about 1 g of the phospholipids and about 1.75 gm of caffeine.12. The method of wherein an effective daily dosage is four 1 g dosages of the phospholipids and four 1 g dosages of caffeine claim 9 , said 1 g dosages delivered approximately every 6 hours in a 24-hour period.13. The method of wherein an effective daily dosage is at least about 4 g of the ...

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17-03-2022 дата публикации

METHOD OF PREVENTING AND TREATING NEURODEGENERATIVE DISORDERS USING SOPHORA JAPONICA L. EXTRACT AS ACTIVE INGREDIENT

Номер: US20220080015A1
Принадлежит:

Provided is a pharmaceutical composition containing, as an active ingredient, a . extract, for the prevention and treatment of neurodegenerative disorders and improvement of cognitive functions. Particularly, it was confirmed that the . extract, according to the present invention, has a significant effect in an Alzheimer's Disease-causing mouse model, through a Y-maze test and a Morris water maze test, thereby confirming that the . extract could be useful as an active ingredient in the pharmaceutical composition for the prevention and treatment of neurodegenerative disorders and the improvement of cognitive functions. 1. A method for preventing or treating a neurodegenerative disorder , comprising:{'i': 'Sophora japonica L', '#text': 'administering to a subject in need thereof a pharmaceutical composition comprising a . extract as an active ingredient.'}2. The method according to claim 1 , wherein the extract is extracted with water claim 1 , a Cto Clower alcohol or a mixture thereof.3. The method according to claim 2 , wherein the Cto Clower alcohol is ethanol or methanol.4. The method according to claim 1 , wherein the neurodegenerative disorder is any one selected from the group consisting of dementia claim 1 , Alzheimer's disease claim 1 , stroke claim 1 , palsy claim 1 , Huntington's disease claim 1 , Pick's disease claim 1 , and Creutzfeldt-Jakob disease.5. A method for preventing or treating a neurodegenerative disorder claim 1 , comprising:{'i': 'Sophora japonica L', '#text': 'administering to a subject in need thereof a health functional food comprising a . extract as an active ingredient.'}6. A method for improving a cognitive function claim 1 , comprising:{'i': 'Sophora japonica L', '#text': 'administering to a subject in need thereof a pharmaceutical composition or a health functional food composition comprising a . extract as an active ingredient.'} This application is a divisional of U.S. application Ser. No. 16/328,194, filed on Feb. 25, 2019, which ...

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08-03-2018 дата публикации

A Beverage

Номер: US20180064126A1
Автор: Woodall Guy
Принадлежит:

A method of producing a beverage concentrate comprising contacting a plant material and/or plant extract with hot water to produce a beverage, wherein the concentration of the plant material and/or plant extract in the hot water is at least 100 grams per litre. The method further comprises filtering the beverage to produce a filtrate, and producing a microbiologically stable beverage concentrate from the beverage or the beverage filtrate. 1. A method of producing a beverage concentrate , the method comprising:contacting a plant material and/or plant extract with hot water to produce a beverage, wherein the concentration of the plant material and/or plant extract in the hot water is at least 100 grams per litre;filtering the beverage to produce a filtrate; andproducing a microbiologically stable beverage concentrate from the beverage or the beverage filtrate.2. A method according to claim 1 , wherein the concentration of the plant material and/or plant extract in the hot water is at least 150 claim 1 , 200 or 250 grams per litre.3. A method according to either or claim 1 , wherein the beverage concentrate is a tea concentrate claim 1 , and preferably a hot tea concentrate.4Camellia sinensis.. A method according to claim 3 , wherein the plant material and/or plant extract comprises the leaves and/or leaf buds of5. A method according to either or claim 3 , wherein the beverage concentrate is a coffee concentrate claim 3 , and preferably a hot coffee concentrate.6Coffea ArabicaCoffea canephora.. A method according to claim 5 , wherein the plant material and/or plant extract comprises the seeds or beans of or7. A method according to either or claim 5 , wherein the beverage concentrate is a fruit and/or herb infusion concentrate.8. A method according to claim 7 , wherein the plant material and/or plant extract comprises fruit and/or herbs.9. A method according to any preceding claim claim 7 , wherein the hot water contacted with the plant material and/or plant extract is ...

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08-03-2018 дата публикации

LIQUID COMPOSITION INCLUDING CITRUS PERICARP ESSENTIAL OIL

Номер: US20180064141A1
Принадлежит: SUNTORY HOLDINGS LIMITED

A liquid composition including 0.2-3.5 vol % of a pericarp essential oil, including 10-300 mg/kg/Acid of limonin, including 10-50 mg/kg/Acid of rutin, having an acidity of 2.0% or less, and being suitable for blending in a beverage. Preferably, the pericarp essential oil, the limonin, and the rutin are derived from citrus fruit, and the liquid composition is preferably obtained using the pericarp of a citrus fruit from which the outermost layer is removed to a degree that oil glands are not broken. 1. A liquid composition comprising an essential oil from peel , limonin , and rutin ,wherein a content of the essential oil from peel is in a range of 0.2-3.5% by volume based on the total amount of the composition;wherein a concentration of the limonin with respect to acidity is in the range of 10-300 mg/kg/Acid;wherein a concentration of the rutin with respect to acidity is in the range of 10-50 mg/kg/Acid;wherein a rutin to limonin weight ratio (rutin/limonin) is 1 or less; andwherein the acidity is 2.0% or less.2. The liquid composition according to claim 1 , wherein the limonin is derived from one or more fruits.3. The liquid composition according to claim 1 , wherein the rutin is derived from one or more fruits.4. The liquid composition according to obtained by use of a solvent and a citrus fruit peel from which a super surface layer has been removed in a thickness such that oil sacs are not ruptured.5. A drink comprising the liquid composition according to at a concentration in a range of 0.1-15% by weight based on the total weight of the drink. The present invention relates to liquid compositions containing essential oils, or essential oils obtained from peel of citrus fruits. More particularly, the present invention relates to liquid compositions that comprise essential oils from peel and specific concentration ratios of limonin and rutin and which are sufficiently low in acidity and bitterness to be capable of inclusion within drinks.Citrus juice obtained by ...

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08-03-2018 дата публикации

RED GINSENG EXTRACT GRANULES, AND METHOD FOR PREPARING RED GINSENG EXTRACT GRANULES USING RED GINSENG EXTRACT POWDER AND FLUIDIZED-BED COATER

Номер: US20180064156A1
Принадлежит: HONGSAMDAN CO., LTD.

The present invention relates to red ginseng extract granules, and a method for preparing the red ginseng extract granules using red ginseng extract powder and fluidized-bed coater, in that a red ginseng extract is dried through a vacuum drier; a red ginseng extract powder of a predetermined size is prepared via a roll mill grinding process; it prepares 100% pure red ginseng extract granules having particle sizes of 1.2 to 1.7 mm through a repeated coating and fluidizing process while spraying a red ginseng extract for spraying on the vacuum-dried red ginseng extract powder having particle sizes of 0.2 to 0.8 mm by a bottom spray method under a fluidized-bed coating condition in a fluidized-bed coater; and then, it sprays and coats a micronized red ginseng powder solution, so that the preparing cost can be reduced through the significant shortening of the fluidized-bed coating time and it has excellent texture and prevention of moisture absorption functions. 1. A method for preparing red ginseng extract granules using red ginseng extract powder and fluidized-bed coater , the method comprising the steps of:an extract drying step of preparing a dried extract mass by drying an red ginseng extract solution;a grinding step of preparing amorphous red ginseng extract powder by grinding the dried extract mass prepared in the extract drying step;a separating step of separating only particle sizes of 0.2 to 0.8 mm from the amorphous red ginseng extract powder;a spherically coating step of preparing red ginseng extract spherical granules in which particle sizes are larger than those of the amorphous red ginseng extract powder through the last spraying and fluidizing step while the particle sizes are increased for each step by spraying and fluidizing a red ginseng extract for spraying on the separated amorphous red ginseng extract powder in the fluidized-bed coater by a bottom spray method under a fluidized-bed coating condition and repeating the spraying and fluidizing in ...

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27-02-2020 дата публикации

METHOD FOR PREVENTING, POSTPONING OR TREATING CHANGES IN THE ANTERIOR/POSTERIOR CHAMBER VOLUME, VITREOUS HUMOUR, AND/OR RETINAL DETACHMENT

Номер: US20200061134A1
Принадлежит: GRAPE KING BIO LTD.

The present invention provides a method for preventing, postponing or treating ocular diseases, including changes in the anterior/posterior chamber volume, vitreous humour, and/or retinal detachment. The method comprises administering to a subject an effective amount of mycelium active substances. A method for preparing mycelium active substances comprises following steps: (a) culturing a mycelium on a plate medium between 15-35° C. for 5-14 days; (b) inoculating the mycelium of step (a) into a flask and culturing the mycelium between 15-35° C. and pH 2-8 for 3-7 days; and (c) inoculating the mycelium of step (b) into a fermenter tank and culturing the mycelium by stirring between 15-35° C. and pH 2-8 for 3-5 days, so as to obtain a mycelium fermentation liquid containing the mycelium active substances. 1Cordyceps cicadaeCordyceps cicadae. A method for preventing , postponing or treating changes in the anterior/posterior chamber volume , vitreous humour , and/or retinal detachment , comprising administering to a subject an effective amount of mycelium active substances , wherein a method for preparing the mycelium active substances comprises following steps:{'i': 'Cordyceps cicadae', '(a) culturing a mycelium on a plate medium between 15-35° C. for 5-14 days;'}{'i': 'Cordyceps cicadae', '(b) inoculating the mycelium of step (a) into a flask and culturing the mycelium between 15-35° C. and pH 2-8 for 3-7 days; and'}{'i': Cordyceps cicadae', 'Cordyceps cicadae', 'Cordyceps cicadae, '(c) inoculating the mycelium of step (b) into a fermenter tank and culturing the mycelium by stirring between 15-35° C. and pH 2-8 for 3-5 days, so as to obtain a mycelium fermentation liquid containing the mycelium active substances.'}2Cordyceps cicadaeCordyceps cicadaeCordyceps cicadaeCordyceps cicadae. The method of claim 1 , wherein the method for preparing the mycelium active substances further includes step (d): freeze-drying the mycelium fermentation liquid and grinding the freeze- ...

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11-03-2021 дата публикации

DEUTERATED CAFFEINE AND USES THEREOF

Номер: US20210068429A1
Автор: Sippy Bradford C.
Принадлежит: Lennham Pharmaceuticals, Inc.

Provided herein are compositions (e.g., pharmaceutical compositions, nutraceutical compositions, foods, beverages, cosmetic compositions, diet supplements) comprising deuterated caffeine. The provided compositions may be useful for treating and/or preventing various diseases and conditions, such as obesity, causing weight loss, increasing metabolic rate, reducing appetite, increasing energy expenditure, increasing urine output, increasing sodium excretion, reducing edema, a pain disorder, apnea, hypotension, an encephalopathy, a neurological or psychiatric disorder, and an inflammatory disorder. 1140-. (canceled)142. The nutritional supplement of claim 141 , wherein at least two to eight instances of Y are deuterium.143. The nutritional supplement of claim 141 , wherein nine or ten instances of Y are deuterium.147. The nutritional supplement of claim 141 , wherein the nutraceutically acceptable salt of the compound of Formula (I) is an HCl claim 141 , sulfate claim 141 , acetate claim 141 , phosphate claim 141 , diphosphate claim 141 , maleate claim 141 , citrate claim 141 , mesylate claim 141 , nitrate claim 141 , tartrate claim 141 , or gluconate salt.148. The nutritional supplement of claim 147 , wherein the salt is a citrate salt.151. The nutritional supplement of claim 141 , comprising about 1 mg to about 10 claim 141 ,000 mg of the compound of Formula (I) claim 141 , or a nutraceutically acceptable salt claim 141 , hydrate claim 141 , or solvate thereof.152. The nutritional supplement of claim 141 , comprising about 1 mg to about 1000 mg of the compound of Formula (I) claim 141 , or a nutraceutically acceptable salt claim 141 , hydrate claim 141 , or solvate thereof.153. The nutritional supplement of claim 141 , comprising about 1 mg/ml to about 100 mg/ml of the compound of Formula (I) claim 141 , or a nutraceutically acceptable salt claim 141 , hydrate claim 141 , or solvate thereof.154. The nutritional supplement of claim 141 , comprising about 10 mg/ml to ...

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15-03-2018 дата публикации

Self-compatible stevia varieties, breeding methods therefrom and methods of preparing novel compositions using said varieties

Номер: US20180070553A1
Принадлежит: PureCircle Sdn Bhd

Novel cultivars of Stevia rebaudiana plant, with a novel genetic trait of self-compatibility, and the advantageous use of this genetic trait in Stevia rebaudiana crossing breeding for increasing steviol glycosides production, including food and beverage products and other consumables, are disclosed.

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15-03-2018 дата публикации

STEVIOL GLYCOSIDES

Номер: US20180070622A1
Принадлежит:

The present invention relates to a steviol glycoside having the formula of (I) 8. A steviol glycoside according to which is fermentatively produced.11. A method for production of a steviol glycoside according to claim 1 , which method comprises:providing a recombinant yeast cell comprising recombinant nucleic acid sequences encoding polypeptides comprising the amino acid sequences encoded by: SEQ ID NO: 61, SEQ ID NO: 65, SEQ ID NO: 23, SEQ ID NO: 33, SEQ ID NO: 77, SEQ ID NO: 71, SEQ ID NO: 87, SEQ ID NO: 73 and SEQ ID NO: 75;fermenting the recombinant yeast cell in a suitable fermentation medium; and, optionally,recovering a steviol glycoside according to any one of the preceding claims.12. A composition comprising a steviol glycoside according to and one or more different steviol glycosides.13. A foodstuff claim 1 , feed and/or beverage which comprises a steviol glycoside according to or a composition thereof.14. A product comprising a steviol glycoside according to or a composition in a sweetener composition or flavor composition.15. A product comprising a steviol glycoside according to or a composition thereof in a foodstuff claim 1 , feed and/or beverage. The present invention relates to steviol glycosides, to methods for producing them, to sweetener compositions, flavour compositions, foodstuffs, feeds and beverages comprising the steviol glycosides and to use of the steviol glycosides in sweetener compositions, flavour compositions, foodstuffs, feeds and beverages.The leaves of the perennial herb, Bert., accumulate quantities of intensely sweet compounds known as steviol glycosides. Whilst the biological function of these compounds is unclear, they have commercial significance as alternative high potency sweeteners.These sweet steviol glycosides have functional and sensory properties that appear to be superior to those of many high potency sweeteners. In addition, studies suggest that stevioside can reduce blood glucose levels in Type II diabetics and can ...

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15-03-2018 дата публикации

Dry composition containing yeast extract and method for manufacturing same

Номер: US20180070623A1
Принадлежит: Ajinomoto Co Inc

The problem of the present invention is to provide a dry composition containing a yeast extract, which shows improved adhesion to facility during production and improved caking during preservation, and has high intensity of taste or high quality of taste, and a production method thereof. The present invention provides a dry composition containing a yeast extract and a dry yeast, which composition has a value calculated by dividing a cell wall fraction (wt %) in the dry yeast by a total nitrogen content (wt %) in the dry yeast of not more than 16. In addition, the present invention provides a method of producing a dry composition, containing a step of drying a yeast extract together with a dry yeast, and having a value calculated by dividing a cell wall fraction (wt %) in the dry yeast by a total nitrogen content (wt %) in the dry yeast of not more than 16.

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07-03-2019 дата публикации

CONSUMABLES

Номер: US20190069580A1
Принадлежит:

Disclosed are sweetened consumables and methods of forming said sweetened consumables that comprise certain sweeteners and a compound of formula (1), 1. A sweetened consumable comprisinga) at least 0.0001% (w/w) of at least one sweetener, including natural and artificial sweeteners, wherein said sweetener includes sucrose, fructose, glucose, high fructose corn syrup, corn syrup, xylose, arabinose, rhamnose, erythritol, xylitol, mannitol, sorbitol, inositol, acesulfame potassium, aspartame, neotame, sucralose, saccharine, or combinations thereof,wherein said at least one sweetener or sweetener combination is present in a concentration above the sweetness detection threshold in a concentration isosweet from 2% to 15% sucrose, andb) a sweetness enhancer comprising hesperitin dihydrochalcone 4″-beta-D-glucoside (HDG), the sweetness enhancer present in a concentration near its sweetness detection threshold in said consumable.2. The sweetened consumable according to wherein the HDG concentration is from 0.3 to 20 ppm.3. The sweetened consumable according to wherein the consumable is selected from dairy product claim 1 , dairy-derived product and dairy-alternative product and wherein the HDG concentration is from 1 to 75 ppm.4. The sweetened consumable according to wherein the consumable has a pH below 6.5 and the HDG concentration is from 0.6 to 30 ppm.5. The sweetened consumable according to wherein the consumable has a pH below 5 and the HDG concentration is from 0.6 to 40 ppm.6. The sweetened consumable according to claim 1 , wherein the consumable is a water-based consumable selected from the group consisting of water claim 1 , aqueous beverage claim 1 , enhanced/slightly sweetened water drink claim 1 , mineral water claim 1 , carbonated beverage claim 1 , non-carbonated beverage claim 1 , carbonated water claim 1 , still water claim 1 , soft drink claim 1 , non-alcoholic drink claim 1 , alcoholic drink claim 1 , beer claim 1 , wine claim 1 , liquor claim 1 , fruit ...

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07-03-2019 дата публикации

Compositions of micronutrients and phytochemicals for optimal human health

Номер: US20190069585A1
Автор: Haase Gerald
Принадлежит:

A formulation comprising at least one phytonutrient, at least one hormone, at least one mineral, at least one dietary vitamin, at least one antioxidant, at least glutathione elevating agent, and at least one other nutrient, and mixtures and combinations thereof. 1. A formulation comprising at least one phytonutrient , at least one mineral , at least one dietary vitamin , at least one antioxidant , at least one glutathione-elevating agent , and at least one other nutrient , and mixtures and combinations thereof.2GinsengGinkgo bilobaMoringaSpirulina. The formulation of wherein said phytonutrient is selected from a group comprising of Bergamot claim 1 , Cannabinoids claim 1 , Chokeberry claim 1 , Cinnamon claim 1 , Curcumin claim 1 , Flax seed claim 1 , Garlic claim 1 , claim 1 , Ginger claim 1 , claim 1 , Grape juice claim 1 , claim 1 , Resveratrol claim 1 , Spearmint claim 1 , claim 1 , Tea claim 1 , and mixtures and combinations thereof.3. The formulation of having at least one hormone claim 1 , wherein said hormone is melatonin.4. The formulation of wherein said mineral is selected from a group comprising Calcium claim 1 , Choline claim 1 , Chromium claim 1 , Iodine claim 1 , Magnesium claim 1 , Selenium claim 1 , Zinc claim 1 , and mixtures and combinations thereof.5. The formulation of wherein said dietary vitamin is selected from a group comprising Vitamin B1 claim 1 , Vitamin B2 claim 1 , Vitamin B3 claim 1 , Vitamin B5 claim 1 , Vitamin B6 claim 1 , Vitamin B7 claim 1 , Vitamin B9 claim 1 , Vitamin B12 claim 1 , Vitamin D claim 1 , and mixtures and combinations thereof.6. The formulation of wherein said antioxidant is selected from a group comprising Vitamin A claim 1 , Vitamin C claim 1 , Vitamin E claim 1 , Coenzyme Q10 claim 1 , Natural mixed carotenoids claim 1 , and mixtures and combinations thereof.7. The formulation of wherein said glutathione-elevating agent is selected from a group comprising Alpha-lipoic acid claim 1 , L-cysteine claim 1 , N-acetyl ...

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15-03-2018 дата публикации

NUTRITIONAL COMPOSITIONS TO ENHANCE MITOCHONDRIAL ENERGY PRODUCTION

Номер: US20180071273A1
Автор: HORN Gregory T.
Принадлежит:

The present disclosure provides nutritional compositions comprising a synergistic effective amount of a NAD− pre-cursor in a combination with an ATP booster. ‘The disclosure provides methods and formulations to enhance natural energy. The disclosure also provides methods and formulations treat mitochondrial energy disorders or diseases. 1. A nutritional composition comprising a pharmaceutically acceptable carrier , and a synergistically effective amount of a combination of NAD+ precursor and an ATP booster.2. The composition of claim 1 , wherein the NAD+ precursor comprises at least one of nicotinamide riboside claim 1 , NAD claim 1 , nicotinic acid claim 1 , nicotinamide claim 1 , nicotinic acid mononucleotide claim 1 , vitamin B3 claim 1 , nicotinamide mononucleotide or a combination thereof.3. The composition of claim 1 , wherein the ATP booster comprises at least one of ancient peat and apple extract claim 1 , adenosine triphosphate disodium claim 1 , cordyceps extract claim 1 , ginseng claim 1 , extract or fractions of Sphaeranthus indicus claim 1 , extract or fractions of Coleus aromaticus claim 1 , extract or fractions of Cissus quadrangular is claim 1 , extract or fractions of Curcuma longa claim 1 , extract or fractions of Garcinia mangostana claim 1 , extract or fractions of Cinnamomum tamala or a combination thereof.4. The composition of claim 1 , further comprising an effective amount of an adaptogen.5Rhodiola rosea,. The composition of claim 4 , wherein the adaptogen comprises at least one of Eleutherococcus senticosus claim 4 , Schisandra chinensis claim 4 , ginseng claim 4 , Gynostemma pentaphyllum claim 4 , ashwagandha or a combination thereof.6. The compositions of claim 1 , further comprising an effective amount of a transporter of fuel for mitochondrial ATP production.7. The composition of claim 6 , wherein the transporter of fuel for mitochondrial ATP production comprises at least one of acetyl L-Carnitine claim 6 , Coenzyme Q10 in ubiquinone or ...

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07-03-2019 дата публикации

SWEET TASTE RECEPTOR ANTAGONIST COMPOSITIONS

Номер: US20190070254A1
Принадлежит:

The present disclosure relates to compositions comprising gymnemic acid, together with a form of zinc to block the unpleasant bitter taste of gymnemic acid as well as to extend the sweet taste blocking properties of gymnemic acid, resulting in palatable compositions for delivery to the oral cavity to block sweet taste receptors located therein. The present disclosure also relates to methods of reducing sugar consumption and reducing calorie intake via administration of such compositions to a subject. 1. A composition comprising gymnemic acid and at least one form of zinc.225-. (canceled) This application is a continuation of U.S. application Ser. No. 15/423,212, filed Feb. 2, 2017, which is a continuation of U.S. application Ser. No. 15/194,411, filed Jun. 27, 2016, now issued as U.S. Pat. No. 9,585,905, which is a continuation of U.S. application Ser. No. 14/738,326, filed Jun. 12, 2015, now issued as U.S. Pat. No. 9,421,217, which claims priority, pursuant to 35 U.S.C. § 119(e), to U.S. Provisional Patent Application Ser. No. 62/011,096, filed Jun. 12, 2014, and U.S. Provisional Patent Application Ser. No. 62/025,725, filed Jul. 17, 2014, the contents of each of which are incorporated herein by reference in their entireties.The present disclosure relates to compositions comprising gymnemic acid, together with a form of zinc to block the unpleasant bitter taste of gymnemic acid as well as to extend the sweet taste blocking properties of gymnemic acid, resulting in palatable compositions for delivery to the oral cavity to block sweet taste receptors located therein. The present disclosure also relates to methods of reducing sugar consumption and reducing calorie intake via administration of such compositions to a subject.Gymnemic acid is extracted from , a woody climbing plant native to India, Africa, and. China. Gymnemic acid is a dietary supplement sold worldwide, primarily in encapsulated forms. (See Ogawa et al., (2004) 45:8-18) Gymnemic acid is known to ...

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18-03-2021 дата публикации

NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF

Номер: US20210077512A1
Принадлежит: ABBOTT LABORATORIES

Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases. 1. A synthetic pediatric formula comprising:hydrolyzed protein;from about 0.01 mg/mL to about 10 mg/mL of at least one of 6′-sialyllactose, 3′-sialyllactose 2′-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, lacto-N-neotetraose, and lacto-N-fucopentaose;from about 0.080 mg/mL to about 0.250 mg/mL of arachidonic acid;from about 0.001 μg/mL to about 5 μg/mL of at least one of lutein, lycopene, and beta-carotene;from about 10 mg/L to about 200 mg/L of a monomeric monophosphate nucleotide component;wherein the synthetic pediatric formula is shelf stable for at least 3 months.2. The synthetic pediatric formula of comprising 0.01 mg/mL to about 5 mg/mL of at least one of 2′-fucosyllactose claim 1 , 3′-sialylactose claim 1 , and 6′-sialyllactose.3. The synthetic pediatric formula of claim 1 , wherein the human milk oligosaccharide component comprises 2′-fucosyllactose which is present in a concentration of from about 0.01 mg/mL to 5 mg/mL.4. The synthetic pediatric formula of claim 1 , wherein the monomeric monophosphate nucleotide component is present in a concentration of from about 42 mg/L to about 1025. The synthetic pediatric formula of claim 1 , wherein the monomeric monophosphate nucleotide component comprises cytidine 5′-monophosphate claim 1 , adenosine 5′-monophosphate claim 1 , guanosine 5′-monophosphate claim 1 , and uridine 5′-monophosphate.6. The synthetic pediatric formula of claim I claim 1 , wherein at least one monomeric monophosphate nucleotide is a free acid and at least one other monomeric monophosphate nucleotide is a salt.7. The synthetic pediatric formula of claim 1 , comprising a combination of lutein claim 1 , lycopene claim 1 , and beta- ...

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14-03-2019 дата публикации

Stabilized fat soluble nutrient compositions and process for the preparation thereof

Номер: US20190075831A1
Принадлежит: OmniActive Health Technologies Ltd

A stabilized composition of fat soluble nutrient(s) includes a water soluble polymer and at least one nutraceutically acceptable excipient. The composition can be in the form of significantly amorphous aqueous microparticulate mixtures or as a solid beadlet product. A process for preparation of a stabilized composition includes a fat soluble nutrient solubilized in an organic solvent embedded in an aqueous polymer phase by evaporation, so as to obtain an aqueous microparticulate mixture. This mixture is stable, soluble and can be formulated for end use or can be layered on inert core for example to obtain stable beadlet(s) for use in solid dosage forms. Such stabilized aqueous microparticulate and solid beadlet compositions exhibit good solubility and dispersibility. Stabilized compositions of fat soluble nutrients can be prepared using industrially convenient equipment and can be formulated as per requirement for use in health applications.

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14-03-2019 дата публикации

COMPOSITIONS COMPRISING NANOPARTICLES DERIVED FROM WHOLE FRUIT AND/OR WHOLE VEGETABLES

Номер: US20190075832A1
Автор: UNDERWOOD Robert Lee
Принадлежит:

Nanoparticles may be derived from whole fruit and whole vegetables to form various compositions. The compositions may have a total anthocyanin concentration ranging from about 60 mg to about 2000 mg per 100 g of nanoparticles. The nanoparticles may have a particles size less than about 1000 nanometers. The compositions may be used in nutraceutical products, dietary supplements, added to food or drinks, topical agents, and combinations thereof. 1. A composition comprising nanoparticles derived from one or more whole fruits and/or one or more whole vegetables , wherein the nanoparticles have a particle size less than about 1000 nanometers , and wherein the composition comprises a total anthocyanin concentration ranging from about 0.06 mg to about 2 mg per 1 g of nanoparticles.2. The composition of claim 1 , wherein the one or more whole fruits is selected from the group consisting of cherries claim 1 , blueberries claim 1 , pomegranates claim 1 , raspberries claim 1 , plums claim 1 , cranberries claim 1 , black chokeberries claim 1 , black elderberries claim 1 , eggplant claim 1 , grapes claim 1 , peaches claim 1 , mangoes claim 1 , bananas claim 1 , apples claim 1 , kiwis claim 1 , gooseberries claim 1 , watermelon claim 1 , jujubes claim 1 , cantaloupes claim 1 , apricots claim 1 , nectarines claim 1 , mulberries claim 1 , figs claim 1 , jackfruit claim 1 , pears claim 1 , carambola starfruit claim 1 , plantains claim 1 , sapodillas claim 1 , passionfruit claim 1 , quinces claim 1 , melons claim 1 , pineapple claim 1 , guava claim 1 , dates claim 1 , tamarinds claim 1 , Saskatoon berries claim 1 , loganberries claim 1 , dewberries claim 1 , sea buckthorns claim 1 , persimmon claim 1 , coconuts claim 1 , lychees claim 1 , citrus fruits claim 1 , and combinations thereof.3. The composition of claim 1 , wherein the one or more whole vegetables is selected from the group consisting of avocados claim 1 , collard greens claim 1 , asparagus claim 1 , lettuce claim 1 , ...

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14-03-2019 дата публикации

Devices and methods for preparing and administering a nutritional formula

Номер: US20190075835A1
Принадлежит: Alcresta Therapeutics Inc

Exemplary embodiments of the disclosure may be drawn to a device having one or more chambers. The one or more chambers may contain immobilized lipase and a phytosterol processing excipient. The device may also include an inlet fluidly connected to one of the one or more chambers, wherein the inlet is configured to receive nutritional formula into one of the one or more chambers. The device may further include an outlet through which nutritional formula is configured to flow after passing through the one or more chambers.

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14-03-2019 дата публикации

Materials and methods for treating hypoxic conditions

Номер: US20190076461A1
Принадлежит: Mitogenetics LLC

This document provides materials and methods for treating hypoxic conditions (e.g., tissue ischemia). Compositions containing a potato polysaccharide preparation and organic selenium can be used to increase or maintain mitochondrial nitric oxide formation. Compositions provided herein can also contain inorganic nitrate.

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31-03-2022 дата публикации

STEVIOL GLYCOSIDES COMPOSITIONS, PRODUCTION METHODS AND USES

Номер: US20220095658A1
Автор: MARKOSYAN Avetik
Принадлежит:

Steviol glycosides compositions are prepared from extracts. The compositions are able to provide a superior taste profile and can be used as sweeteners, sweetness enhancers, flavors, and flavor enhancers in foods, beverages, cosmetics and pharmaceuticals. 2Stevia rebaudianastevia. A sweetener composition comprising the steviol glycosides composition made by the process of claim 1 , and at least one additional sweetening agent selected from the group consisting of: rebaudioside A claim 1 , rebaudioside B claim 1 , rebaudioside C claim 1 , rebaudioside D claim 1 , rebaudioside E claim 1 , rebaudioside F claim 1 , rebaudioside G claim 1 , rebaudioside H claim 1 , rebaudioside rebaudioside J claim 1 , rebaudioside K claim 1 , rebaudioside L claim 1 , rebaudioside M claim 1 , rebaudioside N claim 1 , rebaudioside O claim 1 , dulcoside A claim 1 , steviolbioside claim 1 , rubusoside claim 1 , other steviol glycosides found in plant and mixtures thereof claim 1 , extracts claim 1 , glycosylated steviol glycosides claim 1 , steviol glycosides prepared by chemical claim 1 , enzymatic synthesis or by fermentation of recombinant microorganisms claim 1 , Luo Han Guo extract claim 1 , mogrosides claim 1 , glycosylated mogrosides claim 1 , high-fructose corn syrup claim 1 , corn syrup claim 1 , invert sugar claim 1 , fructooligosaccharides claim 1 , inulin claim 1 , inulooligosaccharides claim 1 , coupling sugar claim 1 , maltooligosaccharides claim 1 , maltodextrins claim 1 , dextrins claim 1 , limited dextrins claim 1 , corn syrup solids claim 1 , glucose claim 1 , maltose claim 1 , sucrose claim 1 , lactose claim 1 , allulose claim 1 , tagatose claim 1 , aspartame claim 1 , saccharin claim 1 , sucralose claim 1 , sugar alcohols and mixtures thereof.3. A flavor composition comprising the steviol glycosides composition made by the process of claim 1 , and at least one additional flavoring agent selected from the group consisting of: cola claim 1 , lemon claim 1 , lime claim 1 , ...

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31-03-2022 дата публикации

Complex mushroom mycelium composition having liver function-improving activity and preparation method therefor

Номер: US20220095663A1
Принадлежит: Giunchan Co Ltd

The present invention relates to a mushroom mycelium complex composition having a liver function-improving activity and a preparation method therefor. The composition is prepared by collectively inoculating the mycelia of three kinds of mushrooms that are Inonotus obliquus, Ganoderma lucidum, and Phellinus linteus, into a naked barley culture medium to obtain a mushroom mycelium complex and extracting the mushroom mycelium complex to obtain an extract of the mushroom mycelium complex. The composition has an effect of improving liver function.

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12-03-2020 дата публикации

AMYLASE INHIBITOR COMPOUNDS, METHODS OF THEIR USE AND COMPOSITIONS THEREOF

Номер: US20200079810A1
Принадлежит:

There are provided compounds of Formula I: 4. The method of claim 1 , wherein the polyethelene glycol comprises 1-5 CHCHO subunits.5. The method of claim 1 , wherein the polyethelene glycol comprises 2-3 CHCHO subunits.6. The method of claims claim 1 , wherein Q is a xylose.7. The method of claim 1 , wherein Q is H.8. The method of claim 1 , wherein Q is OH.10. The method of claim 1 , wherein the mammalian α-amylase is a salivary α-amylase or pancreatic α-amylase.11. The method of claim 1 , wherein the subject is a human.12. The method of wherein the inhibition of the mammalian α-amylase is for the treatment or prophylaxis of dental caries or plaque.13. The method of claim 11 , wherein the inhibition of the mammalian α-amylase is for the treatment or prophylaxis of pre-diabetes claim 11 , diabetes or obesity.14. The method of claim 11 , wherein the administering of the compound of Formula I or a salt thereof to a subject in need thereof is in an effective amount for the treatment or prophylaxis of pre-diabetes claim 11 , diabetes or obesity or for the treatment or prophylaxis of dental caries or plaque. This application is a divisional application of U.S. application Ser. No. 15/661,883, filed on Jul. 27, 2017; which claims the benefit of U.S. Provisional Patent Application Ser. No. 62/367,360 filed on 27 Jul. 2016 entitled “AMYLASE INHIBITORS”.The present invention relates to compounds, methods and compositions for the inhibition of amylase. The present invention further provides compounds, methods and compositions for the inhibition of inhibition of mammalian salivary or pancreatic α-amylase for the treatment or prophylaxis of dental caries and/or plaque or for the treatment or prophylaxis of pre-diabetes, diabetes and/or obesity.Human pancreatic α-amylase (HPA) is an endoglycosidase that cleaves the α-1,4 linked glucose molecules within starch to produce maltose and a range of additional small α-1,4 and α-1,6-linked oligosaccharides that are then further broken ...

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29-03-2018 дата публикации

A METHOD OF PRODUCING MICROPARTICLES OF THE TYPE HAVING A CROSSLINKED, AGGREGATED PROTEIN MATRIX BY SPRAY DRYING

Номер: US20180084819A1
Принадлежит:

A method of producing microparticles by spray drying comprises the steps of providing a spray-drying feedstock solution comprising water, a volatile divalent metal salt, weak acid, 5-15% dairy or vegetable protein (w/v) and 1-20% active agent (w/v). The feedstock solution is adjusted to have a pH at which the volatile divalent metal salt is substantially insoluble. The feedstock solution is then spray-dried at an elevated temperature to provide atomised droplets, whereby the volatile divalent metal salt disassociates at the elevated temperature to release divalent metal ions which crosslink and aggregate the protein in the atomised droplets to produce micro-particles having a crosslinked aggregated protein matrix and active agent dispersed throughout the matrix. 120-. (canceled)21. A spray-dried , food grade , microparticle having an active agent homogenously dispersed throughout a continuous dairy or vegetable protein matrix , in which the protein matrix comprises agglomerated and divalent metal ion crosslinked protein.22. A spray dried microparticle according to and comprising hydrocolloid claim 21 , in which the active agent is homogenously dispersed throughout a continuous protein-hydrocolloid matrix.23. A spray dried microparticle according to in which the hydrocolloid comprises or consists of FOS.24. A spray dried microparticle according to in which the hydrocolloid comprises or consists of citrus fibre.25. A spray dried microparticle according to in which the hydrocolloid comprises or consists of FOS and citrus fibre claim 23 , and in which the active agent is homogenously dispersed throughout a continuous protein-FOS-citrus fibre matrix.26. A spray dried microparticle according to having a dimension of 20-90 microns.27. A spray dried microparticle according to in which the active agent is a cell.28. A spray dried microparticle according to in which the active agent is a compound.29. A spray dried microparticle according to and comprising at least 50% active ...

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21-03-2019 дата публикации

Food composition and cosmetic composition for improving skin beauty, comprising sugar solution with high galactooligosaccharide content

Номер: US20190083377A1
Принадлежит: NEO CREMAR CO Ltd

The present invention relates to a food composition and a cosmetic composition for improving skin beauty, which include galactooligosaccharide and have an ability to increase a skin water holding capacity, an ability to suppress transepidermal water loss, an ability to alleviate wrinkles, and an ability to alleviate erythema.

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21-03-2019 дата публикации

Vitamin D Composition

Номер: US20190083514A1
Принадлежит:

The invention is directed to compositions of vitamin D having enhanced bioavailability and enhanced stability. Methods of making and using the compositions of the invention are contemplated and disclosed. 115-. (canceled)16. A composition of vitamin D having enhanced stability and enhanced bioavailability , the composition comprising vitamin D in contact with at least one comestible oil , wherein said contact increases the bioavailability and stability of said vitamin D compared to control vitamin D that has not been contacted with said comestible oil.17. The composition of claim 16 , wherein said vitamin D is selected from the group consisting of vitamin D2 claim 16 , vitamin D3 claim 16 , and a combination thereof.18. The composition of claim 16 , wherein said comestible oil is selected from the group consisting of tomato seed oil claim 16 , corn oil claim 16 , olive oil claim 16 , canola oil claim 16 , palm oil claim 16 , safflower oil claim 16 , sunflower oil claim 16 , sesame oil claim 16 , peanut oil claim 16 , coconut oil claim 16 , rapeseed oil claim 16 , grapeseed oil claim 16 , soybean oil claim 16 , cotton seed oil claim 16 , and combinations thereof.19. The composition of claim 16 , wherein said vitamin D retains at least 90 percent of its activity 30 days after it is contacted with said comestible oil.20. The composition of claim 16 , wherein said vitamin D retains at least 86 percent of its activity 60 days after it is contacted with said comestible oil.21. The composition of claim 16 , wherein said vitamin D retains at least 72 percent of its activity 90 days after it is contacted with said comestible oil.22. The composition of claim 16 , wherein said contact increases the bioavailability of said vitamin D by about 2 fold.23. The composition of claim 16 , wherein at least one of said vitamin D and said comestible oil are purified.24. The composition of claim 16 , wherein said vitamin D is tomato leaf vitamin D.25. The composition of claim 16 , wherein ...

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21-03-2019 дата публикации

NITRITE FORMULATIONS AND THEIR USE AS NITRIC OXIDE PRODRUGS

Номер: US20190083528A1
Принадлежит:

Compositions comprising from about 40 weight parts to about 1000 weight parts of a botanical nitrate source; from about 20 weight parts to about 500 weight parts of a botanical source of nitrite reduction activity; and from about 4 weight parts to about 100 weight parts of a nitrite salt. Use of said composition in methods of reducing triglycerides or reducing C-reactive protein levels are also provided. 1. A method of reducing a patient's C-reactive protein level , comprising:administering to the patient a composition in a form of a lozenge dissolvable in the mouth, the composition comprising:from about 40 weight parts to about 1000 weight parts of a botanical nitrate source;from about 20 weight parts to about 500 weight parts of a botanical source of nitrite reduction activity;from about 20 weight parts to about 500 weight parts L-citrulline; andfrom about 4 weight parts to about 100 weight parts of a nitrite salt.2. The method of claim 1 , wherein the botanical nitrate source is selected from the group consisting of beet root claim 1 , artichoke claim 1 , holy basil claim 1 , gingko claim 1 , and mixtures thereof and is present at about 200 weight parts;the botanical source of nitrite reduction activity is selected from the group consisting of hawthorn berry, Schisandra, green tea, beet root, pine bark, and mixtures thereof and is present at about 100 weight parts;the L-citrulline is present at about 100 weight parts; andthe nitrite salt is selected from the group consisting of sodium nitrite, potassium nitrite, and mixtures thereof and is present at about 20 weight parts;and the composition further comprises:about 1 weight part vitamin B12 in a form selected from the group consisting of methylcobalamin, cyanocobalamin, and mixtures thereof;about 100 weight parts vitamin C in a form selected from the group consisting of magnesium ascorbate, ascorbic acid, and mixtures thereof; andfrom about 50 weight parts to about 1500 weight parts of one or more other ...

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29-03-2018 дата публикации

SYSTEM AND PROCESS FOR RECOVERING ALGAL OIL

Номер: US20180087003A1
Принадлежит:

Herein disclosed is a method of processing a medium containing algae microorganisms to produce algal oil and by-products, comprising providing the medium containing algae microorganisms; passing the medium through a rotor-stator high shear device; disintegrating cell walls of and intracellular organelles in the algae microorganisms to release algal oil and by-products; and removing the algae medium from an outlet of the high shear device. In an embodiment, disintegration is enhanced by a penetrating gas capable of permeating the cell wall. In an embodiment, enhancement is accomplished by super-saturation of the penetrating gas in the medium or increased gas pressure in a vessel. In an embodiment, the penetrating gas is different from the gas produced by the cell during respiration. A suitable system is also discussed in this disclosure. 1. A system comprisinga rotor-stator high shear device configured to process a medium containing algae microorganisms to produce algal oil and by-products,wherein said high shear device is operated to disintegrate cell walls of and intracellular organelles in the algae microorganisms to release algal oil and by-products,wherein said high shear device comprises an inlet to take in said medium containing algae microorganisms and an outlet for the algae medium to be removed from the high shear device.2. The system of comprising at least two rotor-stator high shear devices fluidly connected in series to process said medium containing algae microorganisms and disintegrate cell walls of and intracellular organelles in the algae microorganisms to release algal oil and by-products.3. The system of further comprising a separation system configured to separate algal oil and by-products from the medium.4. The system of further comprising a conversion system configured to convert algal oil to biodiesel.5. The system of comprising a pressurized vessel to enhance said disintegration.6. The system of comprising a de-watering unit for the medium ...

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01-04-2021 дата публикации

GRANULATION OF A STEVIA SWEETENER

Номер: US20210092971A1
Принадлежит:

A method for making a granulated sweetener is described. The resulting sweetener has a desirably high solubility level. 19-. (canceled)10. A method for producing a sweetener comprising the steps of:{'i': 'Stevia', 'A) introducing a sweetener powder with a solubility of at least about 1 g per 100 g of water at ambient temperature to a roll compaction apparatus to produce a compacted material;'}B) introducing the compacted material to a size reducing apparatus to obtain a granule mixture; and{'i': Stevia', 'Stevia, 'C) fractionating the granule mixture to obtain a granulated sweetener having a particle size ranging from about 140 μm to about 680 μm and having a dissolution rate greater than a dissolution rate of the powder.'}11Stevia. The method of claim 10 , wherein the dissolution rate of the granulated sweetener is at least about 0.75 grams per minute.12. The method of claim 10 , wherein the roll compaction apparatus operates at between about 5 rpm and about 20 rpm claim 10 , and at a roll pressure of between about 10 bar to about 60 bar to produce the compacted material; and the size reducing apparatus comprises a set of sequentially located granulators equipped with rotors rotating at between about 50 rpm to about 2000 rpm to obtain the granule mixture.13SteviaStevia rebaudiana. The method of wherein the sweetener powder is selected from a group consisting of: Stevioside claim 10 , Rebaudioside A claim 10 , Rebaudioside B claim 10 , Rebaudioside C claim 10 , Rebaudioside D claim 10 , Rebaudioside E claim 10 , Rebaudioside F claim 10 , Rebaudioside M claim 10 , Rebaudioside N claim 10 , Rebaudioside O claim 10 , Steviolbioside claim 10 , Dulcoside A claim 10 , Rubusoside claim 10 , other minor glycosides found in plants claim 10 , and a mixture thereof.14Stevia. The method of claim 10 , further comprising the step of combining the sweetener powder with an additional ingredient before introducing the powder to the roll compaction apparatus.15. The method of claim ...

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05-04-2018 дата публикации

Human milk permeate compositions and methods of making and using same

Номер: US20180092374A1
Принадлежит: Prolacta Bioscience Inc

This disclosure features human milk permeates and compositions containing the same obtained from fractionated whole human milk. The oligosaccharide rich permeate and permeate compositions of the present invention are useful as nutritional supplements for pre-term and full term infants, for establishing or maintaining gut flora and for treating the symptoms of inflammatory bowel disease.

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05-04-2018 дата публикации

Free-Flowing Edible Composition, a Foodstuff Comprising It, Methods Employing It and a Method of Making the Composition

Номер: US20180092394A1
Принадлежит:

The present disclosure relates to a free-flowing composition having controllable properties of bulk density, particle morphology, flowability and shakeability suitable, for example, for use on or in a foodstuff or a beverage. The composition includes a blend of: (i) a plurality of substantially discrete composite particles, each composite particle comprising a core of a first edible material provided with a discontinuous surface coating formed from a first plurality of non-uniformly sized particles of a second edible material; and (ii) a second plurality of non-uniformly sized particles of said second edible material. A foodstuff comprising the composition is claimed and so are methods of employing it. The application also claims a method of preparing thee composition, said method comprising the steps of: (a) combining the first edible material, provided in dry particulate form, with the second edible material, provided in dry particulate form; and (b) heating said combination to a forming temperature (T), which is at least equal to the glass transition temperature or softening temperature of the first edible material, with concurrent mixing thereof, so as to coat particles of the first edible material with a first plurality of non-uniformly sized particles of the second edible material, thereby forming composite particles of said composition, and leaving a second plurality of non-uniformly sized particles of the second edible material remaining which are intermingled with said composite particles. 1. A free-flowing edible composition having controllable properties of bulk density , particle morphology , flowability and shakeability , said composition comprising a blend of:(i) a plurality of substantially discrete composite particles, each composite particle comprising a core of a first edible material provided with a discontinuous surface coating formed from a first plurality of non-uniformly sized particles of a second edible material; and(ii) a second plurality ...

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28-03-2019 дата публикации

WHOLE-BEAN SOYMILK HAVING INCREASED BIOAVAILABILITY OF SOY ISOFLAVONES AND METHOD OF PREPARING THE SAME

Номер: US20190090502A1
Принадлежит:

Disclosed herein is a whole-bean soymilk having an increased level of deglycosylated soy isoflavones and a method of preparing thereof. The method includes the steps of subjecting a mixture of a soybean material and water to a comminution treatment so as to obtain a soybean slurry, subjecting the soybean slurry to an enzymatic hydrolysis treatment using a β-glucosidase to obtain a hydrolysate, and subjecting the hydrolysate to a media milling treatment using a milling medium. 1. A method for preparing whole-bean soymilk having an increased level of deglycosylated soy isoflavones , comprising the steps of:subjecting a mixture of a soybean material and water to a comminution treatment, so as to obtain a soybean slurry;subjecting the soybean slurry to an enzymatic hydrolysis treatment using β-glucosidase to obtain a hydrolysate; andsubjecting the hydrolysate to a media milling treatment using a milling medium.2. The method as claimed in claim 1 , wherein the whole-bean soymilk has an average particle size ranging from 10 μm to 61 μm.3. The method as claimed in claim 1 , wherein the whole-bean soymilk is substantially free of glycosylated soy isoflavones.4. The method as claimed in claim 1 , wherein the media milling treatment is conducted at an agitation speed ranging from 2500 rpm to 3200 rpm.5. The method as claimed in claim 1 , wherein the milling medium is selected from the group consisting of glass beads claim 1 , silicon carbide beads claim 1 , zircon beads claim 1 , zirconia beads claim 1 , yttria-stabilized zirconia beads claim 1 , stainless steel beads claim 1 , ceramic beads and combinations thereof.6. The method as claimed in claim 1 , wherein an amount of β-glucosidase used in the enzymatic hydrolysis treatment ranges from 0.05% (w/w) to 0.2% (w/w).7. The method as claimed in claim 1 , wherein the enzymatic hydrolysis treatment is conducted at a temperature ranging from 35° C. to 50° C.8. The method as claimed in claim 1 , further comprising heating the ...

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05-04-2018 дата публикации

PREVENTION OR TREATMENT OF AN INFECTION BY BACTEROIDES THETAIOTAOMICRON

Номер: US20180092949A1
Принадлежит:

The present invention relates to a composition comprising a therapeutically effective amount of or an extract thereof for use in the prevention or treatment of an infection in a subject who is immunodepressed, who is immunosuppressed, who has an immature immune system, and/or who has a weakness, and in which the composition comprises at most six species of bacteria and/or extracts thereof. The infections concerned are mainly intestinal infections, in particular those which affect non-human mammals and/or humans. 116-. (canceled)17B. thetaiotaomicron. A method of treating an infection in a subject with an immunodepressed , immunosuppressed or immature immune system , comprising administering to said subject a composition comprising and/or an extract thereof said composition comprising at most six bacterial species and/or extracts thereof.18. The method according to claim 17 , wherein the subject has an infection.19. The method according to claim 17 , wherein said infection is an intestinal infection.20. The method according to claim 17 , wherein said infection is a bacterial claim 17 , viral claim 17 , parasitic or yeast infection or a combination thereof.21. The method according to claim 20 , wherein said infection is a bacterial infection.22. The method according to claim 20 , wherein said infection is a viral infection.23. The method according to claim 20 , wherein said infection is an infection caused by a parasite.24. The method according to claim 20 , wherein said infection is an infection caused by a yeast.25. The method according to claim 17 , wherein said composition is administered orally.26. The method according to claim 17 , wherein said subject is a non-human animal.27. The method according to claim 26 , wherein said animal is a newborn.28. The method according to claim 17 , wherein said subject is a human.29. The method according to claim 17 , wherein said composition is a functional food or a dietary supplement.30. The method according to claim 17 , ...

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05-04-2018 дата публикации

ERODIUM CRASSIFOLIUM L'HER PLANT EXTRACTS AND USES THEREOF

Номер: US20180092954A1
Принадлежит:

Polar extracts of plants are disclosed as well as pharmaceutical compositions and cosmetic compositions comprising same. Uses of the polar extracts are also disclosed. 1Erodium. A pharmaceutical composition comprising as the active ingredient an extract of tubers of an plant and a pharmaceutically acceptable carrier.2Erodium crassifolium. A pharmaceutical composition comprising as the active ingredient an extract of an L'Her plant and a pharmaceutically acceptable carrier.3Erodium. A polar extract of plant tubers , wherein the extract:(i) does not comprise plant tissue;(ii) has not been bolied; or(iii) is dried.45-. (canceled)6ErodiumErodium crassifolium. The pharmaceutical composition of wherein said plant is L'Her.7Erodium crassifolium. The pharmaceutical composition of claim 2 , wherein said extract is generated from tubers or leaves of said L'Her.8. The pharmaceutical composition of claim 1 , wherein said extract is a polar extract.9. The pharmaceutical composition of claim 8 , wherein said polar extract is a water extract.10. The pharmaceutical composition of claim 8 , wherein said polar extract is an ethanol extract or Acetonitrile:Methanol extract.11. The polar extract of claim 3 , wherein the extract does not comprise material from more than two plants of different species.12. A food or feed comprising the polar extract of .13. The food of claim 12 , being a food additive.14Erodium. A cosmetic composition comprising an extract of tubers of an plant.15. The cosmetic composition of claim 14 , wherein said extract is a polar extract.16Erodium. A method of generating a polar extract of an plant tubers comprising:(a) contacting the tubers with a polar solvent under conditions to allow extraction of soluble agents from said tubers into said solvent to generate an extract; and(b) isolating the extract from said tubers, thereby generating the polar extract.17. The method of claim 16 , wherein said polar solvent is selected from the group consisting of water claim 16 ...

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28-03-2019 дата публикации

AGENT FOR INCREASING INTESTINAL BUTYRIC ACID AND PROLIFERATION AGENT FOR BUTYRIC ACID-PRODUCING BACTERIA

Номер: US20190091248A1
Принадлежит:

[Problem] 18-.9. A method for proliferating butyric acid-producing bacteria , comprising the step of adding 1-kestose to a medium containing butyric acid-producing bacteria to culture the butyric acid-producing bacteria.10. A method for treatment or prevention of intestinal inflammation , fatty liver , diabetes , colorectal cancer , or obesity , comprising the step of increasing the amount or the concentration of butyric acid or the number of butyric acid-producing bacteria in intestines in a human or an animal having or being at risk of having intestinal inflammation , fatty liver , diabetes , colorectal cancer , or obesity by letting take the human or the animal 1-kestose.11. A method for producing a pharmaceutical preparation or a health food for treatment or prevention of intestinal inflammation , fatty liver , diabetes , colorectal cancer , or obesity using 1-kestose. The present invention relates to an agent for increasing intestinal butyric acid, a food composition for increasing intestinal butyric acid, a proliferation agent for butyric acid-producing bacteria, a food composition for proliferating butyric acid-producing bacteria, a method for increasing intestinal butyric acid, a method for proliferating butyric acid-producing bacteria, and a method for treatment or prevention of intestinal inflammation, fatty liver, diabetes, colorectal cancer, or obesity and use of 1-kestose for producing a pharmaceutical preparation for treatment or prevention of these diseases.Butyric acid is a short chain fatty acid and produced by butyric acid-producing bacteria that reside in the intestines in human and animal bodies. Studies in recent years have reported that butyric acid has various physiological effects such as anti-inflammatory effects and colorectal cancer preventing effects and that butyric acid may prevent or ameliorate various diseases.Based on theses, attempts to use butyric acid have been made for prevention and treatment of diseases and health promotion. ...

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26-03-2020 дата публикации

EMULSION OF TRIGLYCERIDE OIL IN GLYCERIN WITH LECITHIN

Номер: US20200093151A1
Автор: Nugent Fredric James
Принадлежит:

A triglyceride oil-in-glycerin emulsion with triglyceride oil in an amount equal to between forty and seventy percent of the emulsion on a weight basis, glycerin in an amount equal to between twenty and sixty percent of the emulsion on a weight basis, and lecithin in an amount equal to between one and ten percent of the emulsion on a weight basis. The lecithin has a hydrophilic lipophilic balance value in the range of four to seven and contains at least ten percent phosphatidylcholine on a weight basis. The free fatty acids in the emulsion have an acid value of less than two. The emulsion does not contain any preservatives. 1. A triglyceride oil-in-glycerin emulsion comprising:(a) triglyceride oil in an amount equal to between forty and seventy percent of the emulsion on a weight basis;(b) glycerin in an amount equal to between twenty and sixty percent of the emulsion on a weight basis; and(c) lecithin in an amount equal to between one and ten percent of the emulsion on a weight basis;wherein the lecithin has a hydrophilic lipophilic balance value in the range of four to seven;wherein the lecithin contains at least ten percent phosphatidylcholine on a weight basis;wherein the free fatty acids in the emulsion have an acid value of less than two; andwherein the emulsion does not contain any preservatives.2. The emulsion of claim 1 , wherein the triglyceride oil is selected from the group consisting of almond oil claim 1 , borage oil claim 1 , coconut oil claim 1 , black currant seed oil claim 1 , chia seed oil claim 1 , camelina oil claim 1 , canola oil claim 1 , echium oil claim 1 , evening primrose oil claim 1 , flaxseed oil claim 1 , hemp seed oil claim 1 , sacha inchi oil claim 1 , high GLA safflower oil claim 1 , liquid coconut oil claim 1 , pumpkin seed oil claim 1 , palm oil claim 1 , palm kernel oil claim 1 , perilla oil claim 1 , peanut oil claim 1 , safflower oil claim 1 , soybean oil claim 1 , sunflower oil claim 1 , walnut oil and wheat germ oil and ...

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12-04-2018 дата публикации

BAKED FOOD PRODUCED FROM ASTAXANTHIN-CONTAINING DOUGH

Номер: US20180098549A1
Принадлежит:

Disclosed is a baked food which comprises a cereal flour, an oil or fat component, astaxanthin and optionally an emulsifying component, has such a structure that the oil or fat component containing the astaxanthin is held in voids in a structure formed by a starch of the cereal flour, and has a porosity of 10 to 70%. Specifically disclosed is a baked food produced from an astaxanthin-containing dough, which can stably hold astaxanthin therein for a long period. 1. A baked food produced from dough , which is capable of stably holding astaxanthin therein for a long period ,comprising a cereal flour, an oil or fat component and astaxanthin,wherein the baked food product has a porosity in the range of 10 to 70%, and wherein the baked food product is capable of holding astaxanthin therein in an amount of 94% by weight or more when stored at room temperature for a period of at least 3 months as compared to the astaxanthin content in the food immediately after baking.2. A baked food produced from dough according to claim 1 , which further comprises an emulsifying component.3. (canceled)4. A baked food produced from dough according to claim 1 , wherein the astaxanthin is any one of an oil extract of astaxanthin claim 1 , an cell wall debris of algae hematococcus or a yeast phaffia debris.5. A baked food produced from dough according to claim 1 , wherein the cereal flour is at least one selected from the group consisting of wheat flour claim 1 , soy flour claim 1 , rice flour claim 1 , corn flour claim 1 , barley flour claim 1 , rye flour claim 1 , oat flour claim 1 , potato flour claim 1 , bean curd lees powder and cornstarch.6camellia. A baked food produced from dough according to claim 1 , wherein the oil or fat component is at least one selected from the group consisting of butter claim 1 , shortening claim 1 , margarine claim 1 , lard claim 1 , egg oil claim 1 , rapeseed oil claim 1 , soybean oil claim 1 , corn oil claim 1 , copra oil claim 1 , palm oil claim 1 , ...

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13-04-2017 дата публикации

Compositions based on plant extracts for inhibition of the 5-alpha reductase

Номер: US20170100447A1
Принадлежит: BIONAP Srl

The present invention refers to nutraceutical, cosmetic or pharmaceutical compositions based on a combination of vegetal extracts from flowers or fruits of Opuntia ficus and Oryza sativa (Black rice) for inhibition of the 5-alpha reductase. In particular, the preparations according to the invention are useful in prevention or treatment of benign prostatic hypertrophy or hyperplasia, of androgenic alopecia and acne.

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12-04-2018 дата публикации

HIGH-PURITY STEVIOL GLYCOSIDES

Номер: US20180100175A1
Принадлежит:

Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2 and reb M2 are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums. 1. A method for producing highly purified target steviol glycosides selected from the group consisting of reb M , reb M2 , reb D2 , and mixtures thereof , comprising the steps of:a. providing an aqueous solution comprising a starting composition comprising steviol glycosides;b. providing a microorganism containing at least one enzyme selected from the group consisting of steviol biosynthesis enzymes, UDP-glycosyltransferases, UDP-glucose recycling enzymes, and a combination thereof;c. contacting the microorganism containing the enzyme with a medium containing the starting composition to produce a medium comprising at least one target steviol glycoside.2. (canceled)3. The method of further comprising the step of:d. separating the target steviol glycoside from the medium to provide a highly purified target steviol glycoside composition.4. (canceled)5E. coli, SaccharomycesAspergillusPichiaBacillusYarrowia. The method of claim 1 , wherein the enzyme is contained in a microorganism selected from the group consisting of sp. claim 1 , sp. claim 1 , sp. claim 1 , sp. claim 1 , and sp.6. The method of claim 1 , wherein the enzyme is provided as a biocatalyst selected from the group consisting of whole cell suspension claim 1 , crude lysate or purified enzymes in free or immobilized form.7. The method of claim 1 , wherein the target steviol glycoside is selected from the group consisting of stevioside claim 1 , reb A claim 1 , reb D claim 1 , reb ...

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04-04-2019 дата публикации

Stabilized canola oil including polyunsaturated fatty acids and oil-soluble antioxidants

Номер: US20190098913A1
Автор: Amir Hossein SABERI
Принадлежит: Cargill Inc

Stabilized oils including an canola oil including EPA and/or DHA and an oil-soluble antioxidant composition comprising rosemary extract and least one of green tea extract, lecithin, and sesamol. The stabilized oils may have an Oxidative Stability Index (“OSI”) at 110° C. of at least 5 hours.

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04-04-2019 дата публикации

New tablettable formulation of lutein and/or zeaxanthin

Номер: US20190098924A1
Принадлежит: DSM IP ASSETS BV

The present invention is directed towards a solid formulation comprising a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution: D [3, 2] in the range of from 0.6 to 1.5 μm and D [v, 0.5] in the range of from 1.1 to 3.5 μm, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. This solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets. Surprisingly these tablets show a low compression loss.

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04-04-2019 дата публикации

Multiphase active substance preparations

Номер: US20190099371A1
Принадлежит: BASF A/S, BASF SA, BASF SE

The present invention relates to solid, at least three-phase active substance preparations, in which two separate phases are embedded multiparticulately into a coherent, active substance-free and antioxidant-free phase, where one of the embedded phases comprises at least one oxidation-sensitive active substance and the second comprises at least one antioxidant. The invention also relates to a method for producing these active substance preparations, and to the use thereof in food supplements, foods, feeds, body care products, and pharmaceuticals.

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