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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 12843. Отображено 100.

05-01-2012 дата публикации

Apparatus and methods for enzymatic debridement of skin lesions

Номер: US20120004627A1

Автор: Amihay Freeman, Eran Hirszowicz, Michal Be'eri-Lipperman

Принадлежит: EnzySurge Ltd, Ramot at Tel Aviv University Ltd

An apparatus for debridement of devitalized tissue in skin lesions, that includes a plurality of height- and angle-adjustable inlet tubes and at least one outlet tube and a member that forms an occlusive seal around a skin lesion. The plurality of inlet tubes is adapted for directing a continuous stream of enzymatic solution to the surface and into the entire volume of the wound bed of the lesion and the at least one outlet is adapted for removing the enzymatic solution, fluids draining from the lesion and tissue debris from the occluded skin lesion.

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Номер записи: 1

09-02-2012 дата публикации

Flexible Endoscopic Ultrasound Guided Biopsy Device

Номер: US20120035500A1

Автор: Shawn Ryan

Принадлежит: Boston Scientific Scimed Inc

A needle for insertion into a living body along a tortuous path comprises an elongate body extending between a proximal end which, during use, remains external to the body and a distal end which, when in an operative configuration, is positioned adjacent to a target structure within the body, a distal portion of the needle including a lumen extending therethrough to a tissue receiving opening at the distal end, the lumen having an inner diameter of at least 0.035 inches and a bending stiffness no greater than 0.08 Nm 2 .

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Номер записи: 2

22-03-2012 дата публикации

Systems and Methods for a Sample Fluid Collection Device

Номер: US20120067112A1

Автор: Adam Ernest Donath, Andreas Knaack, Benjamin Sullivan, Carl Gang Chen, Eric Donsky, Erol Craig Harvey, Fred Harry Davis, Graeme John Bullock, Matthew Daniel Solomon, Sasha Miu, Steve Zmina

Принадлежит: Tearlab Res Inc

A fluid collection device comprising a body comprising a capsule interface, and a capsule configured to interface with the body via the capsule interface and configured to hold a sample receiving chip. The sample receiving chip comprises a substrate that receives an aliquot volume of a sample fluid, wherein the substrate is operatively shaped to receive the aliquot volume of sample fluid through capillary action, and a sample region of the substrate, sized such that the volume of the sample fluid is sufficient to operatively cover a portion of the sample region, whereupon energy properties of the sample fluid can be transduced to produce a sample fluid reading.

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Номер записи: 3

19-04-2012 дата публикации

Device for assaying analytes in bodily fluids

Номер: US20120094303A1

Автор: Leslie Wilson, Matthias W. Engel, Paul Johnson

Принадлежит: ulti med Products International GmbH

A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. Further, the base of the container has a central elevation via which the sample of body fluid can be conveyed from the sampler, by compression thereof on the elevation, to the at least one test strip.

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Номер записи: 4

03-05-2012 дата публикации

Handheld biopsy device with needle firing

Номер: US20120109007A1

Автор: Edward A. Rhad, Harold W. Craig, John A. Hibner, Richard P. Nuchols

Принадлежит: Devicor Medical Products Inc

A biopsy device includes a body, a needle, and a cutter. A motor is operable to both move the cutter relative to the needle and actuate a needle firing assembly to retract and fire the needle relative to the body. The biopsy device also includes a needle rotation assembly that is configured to substantially prevent rotation of the needle about the longitudinal axis when the needle is in a proximal position yet permit rotation of the needle about the longitudinal axis when the needle is in a distal position. A valve assembly of the biopsy device includes a slider that selectively couples a secondary lumen in the needle with either atmospheric air or saline based on the longitudinal position of the slider. The cutter passes through the slider.

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Номер записи: 5

10-05-2012 дата публикации

Bone marrow harvesting device having flexible needle

Номер: US20120116247A1

Автор: John Maurice Marthaler, Kortney Wawrzyniak, Michael Lehmicke, Peter Kurzyna, Sean Kerr, Steven Paul Parmelee

Принадлежит: Synthes USA LLC

A bone marrow harvesting device includes a flexible bone marrow harvesting needle that can bend during operation to prevent the needle tip from piercing the inner cortical wall of the target bone. The needle defines an aspiration channel that defines an intake end that is recessed to reduce the instances that the aspiration channel will be fouled by bone particles or other debris within the cancellous portion.

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Номер записи: 6

17-05-2012 дата публикации

Treatment tool for endoscope

Номер: US20120123201A1

Автор: Jin Hiraoka

Принадлежит: OLYMPUS MEDICAL SYSTEMS CORP

A treatment tool for an endoscope includes a forcep sheath, a first forcep cup and a second forcep cup which are attached to a distal end of the forcep sheath, and which cooperate with each other to be openable/closable as a whole, an operation wire which is movably arranged in the forcep sheath along an axial direction thereof, which is connected to the first forcep cup and the second forcep cup, and which opens/closes the first forcep cup and the second forcep cup when moved in its axial direction, wherein a sharp needle-shaped portion is formed on a distal end of the first forcep cup, the sharp needle-shaped portion extending farther than a distal end of the second forcep cup, and the sharp needle-shaped portion is arranged so that at least a portion thereof overlaps the second forcep cup.

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Номер записи: 7

07-06-2012 дата публикации

Forceps and collection assembly with accompanying mechanisms and related methods of use

Номер: US20120137794A1

Автор: Adam L. Cohen, John B. Golden, Liem T. Vu

Принадлежит: Boston Scientific Scimed Inc

The invention includes a forceps and collection assembly for acquiring and storing a plurality of tissue samples in a single pass, and accompanying mechanisms for use with the forceps and collection assembly. The accompanying mechanisms include an endoscope working channel cap assembly configured to minimize compression of a pouch of the forceps and collection assembly as it traverses a seal of the cap assembly, and a flush adapter configured to be coupled to the pouch so as to assist in removing tissue samples in the pouch by flowing fluid through the pouch.

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Номер записи: 8

21-06-2012 дата публикации

System and method for identification of biological tissues

Номер: US20120156712A1

Автор: Zoltan Takats

Принадлежит: Medimass Kft

The present invention provides for a system, method, and device for analyzing, localizing and/or identifying tissue types. The method includes analyzing, localizing and/or identifying one or more tissue samples, characterized in that the method comprises: (a) generating gaseous tissue particles from a site in the one or more tissue samples, (b) transporting the gaseous tissue particles from the site to an analyser, (c) using the analyser for generating tissue-related data based on the gaseous tissue particles, and (d) analyzing, localizing and/or identifying the one or more tissue samples based on the tissue-related data. The invention can either be used in close conjunction with a surgical procedure, when one or more surgical tools are an integrated part of ionization, or as a separate mass spectrometric probe for the analysis of one or more tissue parts.

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Номер записи: 9

05-07-2012 дата публикации

Biopsy device having a ratchet drive mechanism for driving a biopsy probe assembly

Номер: US20120172752A1

Автор: Chad Van Liere, Himanshu Mahesh Ranpura

Принадлежит: CR Bard Inc

A biopsy device includes a first cannula having a first aperture, a second cannula having a second aperture, and a driver unit. The second cannula is disposed co-axially with the first cannula. At least one of the first aperture and the second aperture has a cutting edge. The driver unit has a ratchet drive mechanism operatively coupled to the first cannula and the second cannula. The ratchet drive mechanism includes a first gear fixedly attached to the first cannula. A second gear is fixedly attached to the second cannula. A torsion spring has a first end portion connected to the first gear and a second end portion connected to the second gear. The torsion spring stores energy which when released drivably rotates one of the first gear and the second gear relative to the other of the first gear and the second gear.

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Номер записи: 10

16-08-2012 дата публикации

Fertility Status Diagnosis System

Номер: US20120209138A1

Автор: Vaclav Kirsner

Принадлежит: Individual

Methods and apparatus for interpreting vaginal measurement data by electronic means without the need for the user to take part in the data interpretation process. More specifically, an intelligent probe monitors folliculogenesis and correlates the ovarian function data to probe profile characteristics of the female reproductive cycle. A fertile window is defined with reference to the correlation between folliculogenesis and probe cyclic profiles.

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Номер записи: 11

06-09-2012 дата публикации

Ergonomic biopsy instrument

Номер: US20120226191A1

Автор: WenHong Neoh

Принадлежит: Cook Medical Technologies LLC

Biopsy instruments having an ergonomic design are described. A biopsy instrument comprises a housing, a needle assembly, and a handle. The needle assembly includes a cannula that defines a lumen and a stylet slidably disposed within the lumen. The housing and the handle have longitudinal axes that intersect at an acute angle.

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Номер записи: 12

27-09-2012 дата публикации

Glucose Monitoring System

Номер: US20120245445A1

Автор: Anita Margarette Chambers, Michael Darryl Black, Trent Huang

Принадлежит: Individual

A body fluid sampling system for use on a tissue site includes a drive force generator and one or more microneedles operatively coupled to the drive force generator. Each of a microneedle has a height of 500 to 2000 μm and a variable tapering angle of 60 to 90°. A sample chamber is coupled to the one or more microneedles. A body fluid is created when the one or more microneedles pierces a tissue site flows to the sample chamber for glucose detection and analysis.

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Номер записи: 13

04-10-2012 дата публикации

Transdermal systems, devices, and methods for biological analysis

Номер: US20120252046A1

Автор: Jiangfeng Fei, Narasinha Parasnis, Swetha Chinnayelka

Принадлежит: Bayer HealthCare LLC

A transdermal test sensor includes a test chamber including a liquid, a reagent system in contact with the liquid, a housing containing the liquid, and a semipermeable membrane. The housing includes an opening, the semipermeable membrane is connected to the housing and covers the opening, and the housing and the semipermeable membrane enclose the liquid and the reagent system. The transdermal test sensor also includes an analyzer in communication with the liquid. When porated tissue is contacted with the semipermeable membrane and sufficient time is allowed for a fluid sample to traverse the porated tissue and for an analyte in the fluid sample to enter the liquid in the transdermal sensor through the semipermeable membrane, a change in at least one optical property or at least one electrical property of the liquid is detected. The change detected is then correlated with the analyte concentration in the fluid sample.

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Номер записи: 14

18-10-2012 дата публикации

Ovulating sensing and analyzing system

Номер: US20120265032A1

Автор: Alfonso Rodriguez, Boaz Beeri, Boaz Mendel, Yoav Ben-David

Принадлежит: Individual

The present invention relates to a system for measuring an oral temperature of a female subject during an ovulation cycle of the female subject for assisting the female subject in determining the next ovulation cycle for fertility and/or birth-control and includes a method and apparatus for predicting a commencement of a new ovulation cycle in a female subject including measuring and communicating the data to a remote computing platform by daily measuring the oral temperatures and calculating an average oral temperature for an ovulation cycle. The daily oral temperature measurements and/or average oral temperatures are also available on external databases and may be used for comparing and checking the current temperature measurements. Different sensors are available for other purposes.

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Номер записи: 15

01-11-2012 дата публикации

Systems and methods for collecting fluid from a subject

Номер: US20120277697A1

Автор: Donald E. Chickering, III, Li Yang Chu, Mark Michelman, Ramin Haghgooie, Shawn Davis

Принадлежит: Seventh Sense Biosystems Inc

Systems and methods for delivering to and/or receiving fluids or other materials, such as blood or interstitial fluid, from subjects, e.g., from the skin. Beading disruptors and/or capillaries may be used for facilitating the transport of fluids from a subject into a device. Beading disruptors may disrupt the “pooling” of bodily fluids such as blood on the surface of the skin and help influence flow in a desired way. A capillary may conduct flow of fluid in the device, e.g., to an inlet of a channel or other flow path that leads to a storage chamber. A vacuum (reduced pressure relative to ambient) may be used to receive fluid into the device, e.g., by using relatively low pressure to draw fluid into the inlet of a channel leading to a storage chamber. The vacuum source may be part of the device.

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Номер записи: 16

08-11-2012 дата публикации

Biopsy device with manifold alignment feature and tissue sensor

Номер: US20120283563A1

Автор: Daniel J. Mumaw, Emmanuel V. Tanghal, Harold W. Craig, Kathryn M. Dodd, Kyle P. Moore, Lois L. Kohnhorst, Patrick A. Mescher, Trevor W. V. Speeg

Принадлежит: Devicor Medical Products Inc

A biopsy system includes a needle, a cutter movable relative to the needle to sever a tissue sample, a processing module, a tissue sensor, and an indicator. The tissue sensor is operable to sense a tissue sample severed by the cutter. The processing module is operable to drive the indicator based on information from the tissue sensor. The indicator may include an audible indicator and/or a visual indicator. The indication provided by the indicator may vary based on sensed qualities of the tissue sample. The indicator may be integrated into a biopsy instrument or may be provided as part of a remote unit. The biopsy system may also include a multi-chamber tissue sample holder. A graphical user interface may indicate which chambers of the tissue sample holder are occupied by tissue samples.

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Номер записи: 17

06-12-2012 дата публикации

Diagnostic oral device

Номер: US20120309042A1

Автор: Elizabeth Gittins, Harsh M. Trivedi, Madhusudan Patel, Sharon Kennedy

Принадлежит: Colgate Palmolive Co

Described herein are devices and methods for identifying the existence of an oral condition in a subject.

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Номер записи: 18

20-12-2012 дата публикации

Device for identifying oral conditions

Номер: US20120322023A1

Автор: Deborah Peru, Douglas Hohlbein, Elizabeth Gittens, Harsh M. Trivedi, Madhusudan Patel, Sharon Kennedy

Принадлежит: Colgate Palmolive Co

The present invention relates to devices and systems for detecting the existence of oral conditions.

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Номер записи: 19

20-12-2012 дата публикации

Single-insertion, multiple sample biopsy device with integrated markers

Номер: US20120323120A1

Автор: Gregory A. Gray, Jon Taylor, Stanley O. Thompson, Timothy J. Coonahan

Принадлежит: CR Bard Inc

The present invention provides for exemplary embodiments of a single-insertion, multiple sample biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release.

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Номер записи: 20

20-12-2012 дата публикации

Kit and method for extracting and storing a skin tissue sample

Номер: US20120323259A1

Автор: Will Richardson

Принадлежит: Individual

A kit of components for extracting and storing a skin tissue sample includes an extraction cartridge with a plurality of blades, an actuator cartridge, and a cap with an aqueous preservative. The actuator cartridge is removeably attached to the extraction cartridge and causes the plurality of blades of the extraction cartridge to extract a skin tissue sample from the person. After the skin tissue sample is extracted, the cap is attached to the extraction cartridge to store and suspend the skin tissue sample in an aqueous preservative preloaded in a container in the cap. A liquid-tight seal prevents bodily fluids from contaminating the actuator cartridge and this enables the actuator cartridge to be removed from the extraction cartridge and to be reused. The extraction cartridge and the attached cap, which store the skin tissue sample, are sent to medical laboratory so that the skin tissue sample can be analyzed.

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Номер записи: 21

24-01-2013 дата публикации

Device for assaying analytes in bodily fluids

Номер: US20130022517A1

Автор: Leslie Wilson, Matthias W. Engel, Paul Johnson

Принадлежит: EXPRESS DIAGNOSTICS INT'L Inc

A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.

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Номер записи: 22

24-01-2013 дата публикации

Single-insertion, multiple sampling biopsy device with linear drive

Номер: US20130023791A1

Автор: Jon Taylor, Stanley O. Thompson, Timothy J. Coonahan

Принадлежит: CR Bard Inc

The present invention provides for exemplary embodiments of a single-insertion, multiple sampling biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release.

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Номер записи: 23

14-02-2013 дата публикации

Sternal locators and associated systems and methods

Номер: US20130041345A1

Автор: Christopher Brian Kilcoin, John Frank Morgan, III, Larry Miller, Robert Titkemeyer

Принадлежит: Christopher Brian Kilcoin, John Frank Morgan, III, Larry Miller, Robert Titkemeyer

Apparatuses, systems, and methods for sternal locators for placement of an intraosseous device into the sternum of a human patient.

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Номер записи: 24

28-02-2013 дата публикации

Full Core Biopsy Device

Номер: US20130053725A1

Автор: Dan C. Ireland, Deborah R. Beck

Принадлежит: Promex Tech LLC

A biopsy device includes coaxially disposed inner and outer needles in which the outer needle tip is configured for obtaining a tissue sample. The inner surface of the outer needle includes a tissue retention feature which may include a countersink and/or a feature formed in the inner surface. The device may be introduced to a biopsy site through an introducer in which the introducer is vented and/or a certain ratio of introducer inner diameter and biopsy device outer diameter is maintained.

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Номер записи: 25

09-05-2013 дата публикации

Container and cap for a biological specimen

Номер: US20130112016A1

Автор: Timothy R. Hansen

Принадлежит: TriPath Imaging Inc

A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container include an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided.

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Номер записи: 26

09-05-2013 дата публикации

Sample collection tool

Номер: US20130116596A1

Автор: Adele Jackson, Ellen Joan Maclean, H. Chaim Birnboim, Michael Beach, Mike Sirois, Rafal Michal Iwasiow, Rama Nadia Panford-Walsh, Rod Muir, Romeo Graham, Roy Sunstrum

Принадлежит: DNA Genotek Inc

A sample collection tool comprises a collection end configured for collecting a sample. Optionally, the sample is collected from within a body cavity of an animal without causing significant discomfort or injury to the animal. A first handle portion has a first end connected to the collection end and a second end. A second handle portion is connected to the second end of the first handle portion by a breakable connection. The second end of the first handle portion has at least one winglet. The at least one winglet is compliant in a preferential direction. The breakable connection is ruptured at least in part when the at least one winglet is forced in the preferential direction.

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Номер записи: 27

23-05-2013 дата публикации

Body fluid testing device

Номер: US20130131480A1

Автор: Hugo Schrem, Volker Zimmer, Werner Ruhl

Принадлежит: Roche Diagnostics Operations Inc

Body fluid testing device for analyzing a body fluid comprises a test media tape adapted to collect the body fluid. The test media tape comprises a tape and test media portions. A free tape portion without test medium is located between successive test media portions. The testing device further comprises a supply portion. The supply portion comprises a housing in which uncontaminated test media tape is contained. The housing further has an opening for withdrawing test media tape from the housing. The testing device further has a sealing means for closing the opening against the surrounding. A free tape portion of the test media tape is located between a wall of the housing and the sealing means when the sealing means closes the opening. Further aspects concern a test media cassette with sealing means and a method for providing test media while holding them sealed against humidity during onboard storage.

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Номер записи: 28

30-05-2013 дата публикации

Delivering and/or receiving fluids

Номер: US20130138058A9

Автор: A. David Boccuti, Christopher J. Morse, Donald E. Chickering, III, Greg Fisher, Javier Gonzalez-Zugasti, Maisam Dadgar, Mark Michelman, Ramin Haghgooie, Richard L. Miller, Scott James, Shawn Davis

Принадлежит: Seventh Sense Biosystems Inc

The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication.

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Номер записи: 29

06-06-2013 дата публикации

Biopsy device with slide-in probe

Номер: US20130144188A1

Автор: Edward A. Rhad, John A. Hibner, Kevin M. Fiebig

Принадлежит: Devicor Medical Products Inc

An exemplary ultrasound biopsy device includes a probe and a holster. The probe is insertable into the holster to form a completed assembly. To assemble the probe to the holster, the probe is initially slid laterally onto the holster and then slid forward to latch the probe into engagement with the holster. The holster is coupled to a vacuum control module by one or more conduits and a power cable. The conduits and/or power cable may be retracted into the vacuum control module. The probe of the biopsy device includes a blade assembly at the distal end. The blade assembly comprises a blade that snaps onto a nosecone via a pair of resilient notched ends. A frictional fitting needle cover can be inserted over the needle and blade assembly to protect the user from the sharp blade.

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Номер записи: 30

27-06-2013 дата публикации

Sample Collection System with Integrated Drug Testing Apparatus

Номер: US20130164190A1

Автор: James Plante

Принадлежит: Individual

A urine sample collection and drug test kit includes a receiving vessel with a specially prepared mechanical holder. A prepared chemical test carrier insert is pushed into the holder to form a drug test system. The drug test kit additionally includes purpose functional cap integrated with the receiving vessel whereby a sure liquid tight seal is easily established by merely applying a pressure to the cap to complete a press fit seal between the cap and receiving vessel at their respective aperture peripheries. The carrier insert is fashioned to accommodate an array of drug test reagent strips, for example nitrocellulose strips having prescribed chemistry integrated thereon. Receiving vessels of these systems are particularly characterized in that they include a viewing window carefully aligned with respect to the mechanical holder whereby the carrier insert may be viewed as it is held indexed and fixed with respect to the exterior surface of the receiving vessel.

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Номер записи: 31

25-07-2013 дата публикации

Soft tissue coring biopsy devices and methods

Номер: US20130190651A1

Автор: James William VETTER

Принадлежит: Transmed7 LLC

A biopsy device comprises a coring and transport assembly and a distal beak assembly. The distal beak assembly may be coupled to or near a distal end of the coring and transport assembly and may comprise at least one movable cutting element. The distal beak assembly may be configured to rotate about an axis, and assume at least a first open configuration operative to enable the at least one cutting element to core through tissue and a second closed configuration operative to enable the at least one cutting element to move through the tissue and to sever a cored specimen from the tissue.

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Номер записи: 32

01-08-2013 дата публикации

Disposable hand-held device for collection of exhaled breath condensate

Номер: US20130197388A1

Автор: Jeffrey A. Kline

Принадлежит: Charlotte Mecklenburg Hospital

A breath condensate collection apparatus comprising a central chamber, a breath input assembly, a plunger assembly and a breath condensate collection port. The central chamber has inner and outer side walls with a coolant material sealed in between. The breath input assembly is disposed on the side of the central chamber in fluid communication with the chamber interior. The plunger assembly has a piston, slidably disposed in the chamber, and a handle extending from a first end of the chamber. The collection port is disposed at the second end of the central chamber in fluid communication with the interior of the chamber. Obstructive structures may be arranged in the chamber interior for increasing the surface area on which condensate may form. The apparatus may also include an outlet assembly that may be removed and replaced with a sampling well into which the condensate may be washed with a buffer solution.

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Номер записи: 33

15-08-2013 дата публикации

Sampling device and method for preparing the same

Номер: US20130211288A1

Автор: Meindert Durk Zwart

Принадлежит: Rovers Holding BV

The present invention relates to a sampling device for sampling a body cavity, in particular for sampling the vagina and/or cervix. The sampling device comprises a tube having two open ends, a sample-collecting member and a plunger. The plunger is inserted in the tube, with the distal plunger end protruding from the distal tube end, and carries the sample-collecting member at the proximal tube end. The plunger is displaceable in the proximal direction in the tube from a retracted introduction position into an extended sampling position. In the introduction position, the sampling member is situated inside the tube and protrudes from the tube in the sampling position.

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Номер записи: 34

29-08-2013 дата публикации

Lung biopsy needle

Номер: US20130225996A1

Автор: David H. Dillard, Desmond O'Connell, Hugo X. Gonzalez, Péter HOFFMAN

Принадлежит: Spiration Inc

Systems, methods, and devices for biopsying tissue, in particular lung nodules, with a flexible needle are described herein. Preferably, the flexible needle is able to articulate or bend so as to provide access to areas previously difficult or impossible to biopsy. Further embodiments provide for steering and navigating the flexible needle to a region to be biopsied.

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Номер записи: 35

29-08-2013 дата публикации

Lung biopsy needle

Номер: US20130225997A1

Автор: David H. Dillard, Desmond O'Connell, Hugo X. Gonzalez, Péter HOFFMAN

Принадлежит: Spiration Inc

Systems, methods, and devices for biopsying tissue, in particular lung nodules, with a flexible needle are described herein. Preferably, the flexible needle is able to articulate or bend so as to provide access to areas previously difficult or impossible to biopsy. Further embodiments provide for steering and navigating the flexible needle to a region to be biopsied.

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Номер записи: 36

29-08-2013 дата публикации

Soft tissue coring biopsy devices and methods

Номер: US20130226031A1

Автор: James William VETTER

Принадлежит: Transmed7 LLC

A biopsy device comprises a coring and transport assembly and a distal beak assembly. The distal beak assembly may be coupled to or near a distal end of the coring and transport assembly and may comprise at least one movable cutting element. The distal beak assembly may be configured to rotate about an axis, and assume at least a first open configuration operative to enable the at least one cutting element to core through tissue and a second closed configuration operative to enable the at least one cutting element to move through the tissue and to sever a cored specimen from the tissue.

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Номер записи: 37

12-09-2013 дата публикации

Flexible ring pessary

Номер: US20130237771A1

Автор: Andreas Ziegner, Holger RUNKEWITZ

Принадлежит: VivoSensMedical GmbH

The present disclosure suggests an apparatus for determining at least one parameter in the vaginal channel of a user. The apparatus comprises a flexible pessary and a measurement unit comprising at least one sensor for measuring the at least one vaginal parameter. The measurement unit is reversibly mountable to the flexible pessary.

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Номер записи: 38

12-09-2013 дата публикации

Surgical device for the collection of soft tissue

Номер: US20130237878A1

Автор: David S. Iverson, John A. Hibner, Jon D. Buzzard, Michael E. Piller, Michael J. Reiter, Salvatore Privitera

Принадлежит: Devicor Medical Products, Inc.

A biopsy device comprises a handpiece, a fluid collection system, and a power transmission source. The handpiece is configured for grasping by a single hand, and is independently manipulatable by hand for movement of the instrument toward and away from the patient. An elongated piercer extends from the distal end of the handpiece. The piercer has a sharpened distal end for entering the tissue and a port located proximal to the sharpened distal end for receiving a portion of tissue mass. An elongated cutter is disposed coaxially relative to a piercer lumen of the piercer. A distal blade of the cutter slides distally past the port of the piercer to sever the tissue portion drawn into the port by vacuum. The handpiece further comprises a holster for detachably connecting a cutter rotational transmission and a cutter axial transmission to the power transmission source.

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Номер записи: 39

12-09-2013 дата публикации

Treatment tool for biopsy and tissue collecting method

Номер: US20130237879A1

Автор: Hideo Takachi, Masatoshi Tonomura, Saori Takeuchi, Yutaka Yanuma

Принадлежит: OLYMPUS MEDICAL SYSTEMS CORP

This treatment tool for biopsy includes a needle tube, which having a first aperture and a second aperture. The first aperture and the second aperture communicate with the tubular space. The second aperture is provided in a side surface of the needle tube at more proximal end side than the first aperture. In a cross-section of the second aperture, a distal end circular arc portion of an end surface of the second aperture has a distal end side inclined surface that is inclined so as to be positioned gradually outwards of a radial direction of the needle tube towards the distal end side, and a proximal end circular arc portion of the end surface of the second aperture has a proximal end inclined surface that is inclined so as to be positioned gradually outwards of the radial direction of the needle tube towards the proximal end side.

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Номер записи: 40

19-09-2013 дата публикации

Icon-based user interface on biopsy system control module

Номер: US20130245494A1

Автор: Gregory W. Johnson, Patrick A. Mescher, Raj G. Raghavendran, Robert F. Weikel, Trevor W.V. Speeg, Wells D. Haberstich

Принадлежит: Devicor Medical Products, Inc.

A biopsy system includes a biopsy device and a vacuum control module. The biopsy device includes a cannula and a cutter that translates relative to the cannula to obtain tissue samples. The vacuum control module includes a source of vacuum in communication with the cutter and a user interface. The user interface includes a first page and a second page. The first page has a first graphical representation to indicate the operational status of the biopsy device and does not accept user inputs to alter the operational status of the biopsy device. The second page has at least one icon to adjust the operational status of the biopsy device indicated on the first page and a second graphical representation to indicate the adjustment to the operational status of the biopsy device. The user interface includes a user input feature to select the first page or the second page.

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Номер записи: 41

03-10-2013 дата публикации

Surgical biopsy system with remote control for selecting an operational mode

Номер: US20130261498A1

Автор: Dan F. Dlugos, John A. Hibner, Jon D. Buzzard, Mark A. Burdorff

Принадлежит: Devicor Medical Products Inc

A surgical biopsy system is provided for removing at least one tissue sample from a surgical patient. The surgical biopsy system comprises an elongated, hollow piercer and a cutter rotatably and axially positionable relative to the piercer. The piercer has a lateral port for receiving the tissue sample into the piercer. The surgical biopsy system further comprises a power transmission source operatively connected to the cutter for rotating and translating the cutter, a control unit, and a display mounted in a display frame for showing an operator a plurality of operational modes of the surgical biopsy system. The surgical biopsy system further comprises at least one control button operatively connected to the control unit by a circuit and remotely located from the control unit. The operator may actuate the control button(s) to select any one of the operational modes and the selected operational mode is visually identifiable on the display.

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Номер записи: 42

17-10-2013 дата публикации

Biological information monitoring apparatus

Номер: US20130274617A1

Автор: Osamu Uchida, Shogo Maeda, Shoichi Hosaka, Toshiki Aoki

Принадлежит: Nihon Kohden Corp

A biological information monitoring apparatus includes: a measurer which is configured to measure biological information of a subject; a display on which a measurement value of the biological information measured by the measurer is displayed; a calibration controller which, when a predetermined condition is satisfied, is configured to perform a calibration process on the measurer; a time measurer which is configured to acquire a remaining time before the calibration process is ended; and a display controller which is configured to cause an index indicating the remaining time to be displayed on the display.

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Номер записи: 43

16-01-2014 дата публикации

System for collecting and preserving tissue cores

Номер: US20140017771A1

Автор: Brian C. Dougherty, Joseph L. Mark, Mick Trompen

Принадлежит: Nico Corp

A thermal system for preserving tissue is disclosed. The cooling system comprises a base member, a temperature control sleeve constructed of a thermally conductive material, and a selectively removable lid member. The base member defines a reservoir and receives the temperature control sleeve. The temperature control sleeve at least partially defines a tissue collector chamber that is configured to receive a tissue collector. The temperature control sleeve is in communication with the reservoir. The reservoir is configured to receive a cooling medium. A slit formed within the tissue collection chamber that is sized to receive a tubing connected to the tissue collector therethrough. The lid member is configured to be selectively attached to the base member, and permit access to a tube mount for the tissue collector when the lid is attached to the base member.

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Номер записи: 44

30-01-2014 дата публикации

Biopsy device with vacuum assisted bleeding control

Номер: US20140031716A1

Автор: Bennie Thompson, Gavin M. Monson, John A. Hibner, Michael R. Ludzack, Robert F. Weikel, Jr., Trevor W.V. Speeg

Принадлежит: Devicor Medical Products Inc

A biopsy device and method are provided for obtaining a tissue sample, such as a breast tissue biopsy sample. The biopsy device includes a disposable probe assembly with an outer cannula having a distal piercing tip, a cutter lumen, and a cutter tube that rotates and translates past a side aperture in the outer cannula to sever a tissue sample. The biopsy device also includes a reusable hand piece with an integral motor and power source to make a convenient, untethered control for use with ultrasonic imaging. External vacuum holes along the outer cannula (probe) that communicate with a vacuum and cutter lumen withdraw bodily fluids while a hemostatic disk-shaped ring pad around the probe applies compression to an external hole in the skin and absorbs fluids.

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Номер записи: 45

06-02-2014 дата публикации

Biopsy system

Номер: US20140039343A1

Автор: Edward A. Rhad, Jessica Pyzoha Leimbach, John R. Andrisek, John S. Ehlert, Kathryn M. Dodd, Kevin M. Fiebig, Kyle P. Moore, Morgan R. Hunter, Patrick A. Mescher, Trevor W.V. Speeg

Принадлежит: Devicor Medical Products Inc

A biopsy system includes various features. A tissue sample holder kit of the system comprises a rotatable member with chambers configured to receive tissue receiving features of a tissue sample tray. A biopsy device of the system includes user input features and user feedback features disposed on a body. A user interface of the system includes a graphical representation of a tissues ample holder. A biopsy site marker applier of the system includes markings associated with different biopsy device configurations. The biopsy system may undergo a multi-step initialization process. In operation, the biopsy system may execute pneumatic control algorithms including the use of vacuum, saline, and atmospheric air.

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Номер записи: 46

06-02-2014 дата публикации

Device and method for collecting tissue samples

Номер: US20140039346A1

Автор: Alexandra J. Gillespie

Принадлежит: Individual

A tissue sampling device includes a single wire spirally wrapped at its half-length. This wire is partially covered in a hollow flexible tube. Located along the distal end portion of the wire is a brush with bristles that are used for collecting a tissue sample. An atraumatic bulb is located on the extreme distal end of the wire to protect the tissue during insertion. The flexible tube is contained within a sheath to cover the brush during insertion and after tissue collection. The sheath is moved back to expose the brush and allow for collection of a tissue sample. The flexible tube is scored in centimeter gradations to allow measurement of the insertion depth of the device. The atraumatic bulb may be more elongated than round, such as egg-shaped, elliptical, oblong, ovate, ovoid, pear-shaped, bullet-shaped, and the like.

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Номер записи: 47

13-02-2014 дата публикации

Medical instrument adaptor and methods of use

Номер: US20140046304A1

Автор: Gary Kappel, Mark Wood, Norman May, Sean Fleury

Принадлежит: Boston Scientific Scimed Inc

Embodiments of the disclosure include an adaptor for a medical instrument configured for insertion into a body of a patient. The adaptor may comprise a housing defining an internal recess configured to receive a portion of the medical instrument. The internal recess may further include geometric configurations configured to secure the housing to the medical instrument. The outer configuration of the adaptor may be compatible with a separate medical device.

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Номер записи: 48

20-02-2014 дата публикации

Apparatus and methods for removing spring based multiple biopsy specimens from multiple biopsy storage cylinders before and after biopsy fixation and histopathological processing

Номер: US20140052019A1

Автор: David S. Zimmon

Принадлежит: Individual

An apparatus for removing biopsies from spring based multiple biopsy storage cylinders for analysis. The storage cylinders and spring based biopsy mechanism permit 360 degree biopsy mechanism rotation and increase the number and diameter of biopsies stored. Additional storage cylinder improvements allow closed storage cylinder opening for removing internal plastic cylinders or biopsies before fixing, thereby leaving the same multiple biopsy instrument available for additional biopsies on the same patient. The improvements allow for removing the surrounding biopsy mechanism and biopsies from closed storage cylinders after actuator removal and histopathological processing of biopsies to paraffin embedding. Additionally apparatuses, tools and methods are described for simultaneously separating numerous actuators from storage cylinders and removing numerous paraffin embedded biopsies from storage cylinders and surrounding biopsy mechanisms for histopathological slide fabrication.

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Номер записи: 49

06-03-2014 дата публикации

Sampling System

Номер: US20140066807A1

Автор: Berndt Sjoberg, Erik Wilander, Sören Nygren, Ulf Lundkvist

Принадлежит: APROVIX AB

A sampling system comprises a mailing package; a cell sampling device comprising a flexible shaft having a handle at one end, wherein the shaft is configured to allow an individual to self collect a cell sample from mucous tissue, and a sample collecting element removably connectable with the other end of the shaft and operable to collect a cell sample from mucous tissue of an individual; and a sealable unit, wherein the unit is configured to store the sample collecting element having a cell sample thereon configured to receive the remaining components of the system for delivery to a user.

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Номер записи: 50

27-03-2014 дата публикации

Systems and methods for surgical and interventional planning, support, post-operative follow-up, and, functional recovery tracking

Номер: US20140088990A1

Автор: Christopher Nordstrom, Cody Cranson, David D. Konieczynski, Douglas Raymond, Hassan A. Serhan, James J. Roveda, James Paiva, Jennifer DiPietro, John P. Griffin, Jonathan Bellas, Mark T. Hall, Mary L. Fowler, Matthew Parsons, Max Reinhardt, Michael A. Slivka, Michael O'Neil, Michelle LeClerc, Namal Nawana, Nicholas Pavento, Robert E. Sommerich, Sean P. Selover, Thomas Martin, William C. Horton, William J. Frasier

Принадлежит: DePuy Mitek LLC, DePuy Orthopaedics Inc, DePuy Synthes Products Inc, DePuy Synthes Sales Inc

Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s). The system can manage the tracking of multiple patients, thereby allowing for data comparison between similar aspects of medical treatments and for learning over time through continual data gathering, analysis, and assimilation to decision-making algorithms.

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Номер записи: 51

03-04-2014 дата публикации

Guide sheath and medical system

Номер: US20140094658A1

Автор: Yusuke Nomura

Принадлежит: OLYMPUS MEDICAL SYSTEMS CORP

A guide sheath includes: an elongated member extending along a longitudinal axis; a manipulation wire extending along the longitudinal axis of the elongated member so as to be capable of advancing and retracting; a bent section formed of a thermoplastic resin in a tubular shape and configured to be bent in accordance with advance or retraction of the manipulation wire; and a first hard section provided at a distal end surface of the bent section and formed by cross-linking the thermoplastic resin to which a distal end section of the manipulation wire is fixed.

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Номер записи: 52

10-04-2014 дата публикации

Methods, Systems, and Products for Monitoring Health

Номер: US20140099594A1

Автор: Behzad Shahraray, Horst J. Schroeter, II Robert Raymond Miller, James H. Pratt, Kevin A. Li, Troy C. Meuninck

Принадлежит: AT&T INTELLECTUAL PROPERTY I LP

Methods, systems, and products monitor a person's regimen for medicinal and dietary restrictions. When the person's regimen requires a liquid medication or supplement, an oral instrument is commanded to dispense a dosage of fluid. The oral instrument stores a reservoir of the fluid. If the oral instrument is a spoon, for example, the spoon may automatically dispense cough syrup or other medicine. A toothbrush, likewise, may automatically dispense mouthwash. A sensor may confirm presence of the oral instrument in the person's mouth, thus ensuring the dosage of fluid is ingested.

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Номер записи: 53

06-01-2022 дата публикации

COLLECTION AND TREATMENT OF A BIOFLUID SAMPLE

Номер: US20220000457A1

Автор: FABRIZIO Eve F., HENDRIX Pamela, HOLLER Kraig, KEYGHOBAD Seyamak, KLEIN Jessica, PATEL Bindi, ZITEK Trevor

Принадлежит:

A system can facilitate pre-treatment a biofluid sample for various applications for monitoring and/or tracking a subject's health. The system includes a sample collection component that can collect the biofluid sample. The system also includes a mixing component that includes a media with a material. Upon adding the biofluid sample to the mixing component, the biofluid sample mixes with the media. The system also includes a filter component that can filter the media from the biofluid sample. After the media is filtered from the biofluid sample, the biofluid sample can be provided to an analyte analysis application. 1. A method comprising:adding a biofluid sample to a media comprising a carbon-containing material, wherein the biofluid sample comprises a liquid, an analyte and at least one contaminant;mixing the biofluid sample and the media to reduce a concentration of the at least one contaminant in the biofluid sample;filtering the media from the biofluid sample,wherein the mixing and/or the filtering uses a mechanical mechanism; andproviding the biofluid sample for analysis.2. The method of claim 1 , wherein the analysis comprises the detecting the analyte in the biofluid sample.3. The method of claim 1 , wherein the carbon-containing material eliminates at least a portion of the at least one contaminant in the biofluid sample.4. The method of claim 1 , wherein the carbon-containing material comprises activated charcoal claim 1 , activated carbon claim 1 , carbon black claim 1 , graphite claim 1 , graphene claim 1 , oxidized graphene claim 1 , and/or reduced graphene.5. The method of claim 1 , further comprising collecting the biofluid sample claim 1 , wherein the biofluid sample comprises a bodily fluid.6. The method of claim 5 , wherein the bodily fluid comprises tears claim 5 , saliva claim 5 , urine claim 5 , serum claim 5 , plasma claim 5 , and/or blood.7. The method of claim 1 , wherein the analysis comprises detecting an amount of the analyte in the ...

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Номер записи: 54

03-01-2019 дата публикации

Ophthalmic lens with glucose sensitive pad and method for manufacturing same

Номер: US20190000359A1

Автор: Hsiu-Wen Chien

Принадлежит: Hon Hai Precision Industry Co Ltd

An ophthalmic lens with glucose sensitive pad to indicate body glucose levels by changing color when in contact with tears from the eye includes a matrix, the matrix comprising a contact surface, the contact surface defining a micro-channel; and at least one glucose sensitive pad received in the micro-channel. A method for manufacturing an ophthalmic lens with glucose sensitive pad is also provided.

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Номер записи: 55

07-01-2021 дата публикации

Real-Time Sampling Device

Номер: US20210000334A1

Автор: Christopher R. Ralph, Jason T. Panzenbeck

Принадлежит: Gyrus ACMI Inc

An elongated access device used in a medical system. The elongated access device slidably receives a medical tool and an ultrasound probe. The elongated access device includes a sheath and an intraluminal tip attached to the distal end of the sheath. The intraluminal tip includes ramp and nose donuts being spaced apart from one another and configured to be attached to one or more elongated sleeves. One or more orientation pins are engaged with the respective ramp and nose donuts and may be anchored within the sheath. The medical tool is engaged with a ramp formed in the ramp donut or a ramp received within the ramp donut. The ultrasound probe is configured to engage with the intraluminal tip so as to ensure that the medical tool directionality is oriented toward a target during a procedure.

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Номер записи: 56

05-01-2017 дата публикации

INTRODUCER SHEATH AND PUNCTURE TOOL FOR THE INTRODUCTION AND PLACEMENT OF A CATHETER IN TISSUE

Номер: US20170000361A1

Автор: McCabe Aaron, Meyering Emily Rolfes, SCHEURER ELIZABETH

Принадлежит:

Disclosed embodiments include methods and devices for introducing a sheath into a human or animal subject. Some embodiments include a puncture tool that may simultaneously deliver a sheath and a needle to a desired anatomical location. The needle may be removed and the sheath may be used to define a space that may be used to conduct a procedure. 1. A medical device comprisinga handle;a needle having a proximal end releasably connected to a distal end of the handle by a fastener;a sheath disposed around the needle, a proximal end of the sheath releasably connected to the distal end of the handle by the fastener; anda barrier disposed around the sheath and the needle, having a proximal zone and a distal zone connected by a covering.2. The medical device of claim 1 , wherein the fastener comprises a Luer fitting or a 3-way stopcock.3. The medical device of claim 1 , wherein the needle comprises a tip having an angle.4. The medical device of claim 3 , wherein the angle of the tip is between 5 and 10 degrees.5. The medical device of claim 1 , wherein the handle further comprises a port in fluid connection with an inner lumen of the sheath.6. The medical device of claim 1 , wherein the sheath comprises a braided material.7. The medical device of claim 1 , wherein the handle further comprises a button for releasing the needle.8. The medical device of claim 1 , wherein the handle is egg-shaped.9. A method for performing a procedure at a surgical site of a human or animal subject claim 1 , comprising: a handle;', 'a needle releasably connected to the handle;', 'a sheath disposed around the needle and releasably connected to the handle;', 'a barrier disposed around the sheath and the needle, the barrier being in a collapsed configuration and having a proximal zone attached to the proximal end of the sheath and a distal zone connected to the proximal zone by a covering;, 'receiving a medical device comprisingdeploying the barrier to an expanded configuration;attaching the ...

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Номер записи: 57

04-01-2018 дата публикации

ALLERGY SKIN TEST APPLICATOR

Номер: US20180000400A1

Автор: SMOLLAR MARVIN

Принадлежит:

An allergy testing kit contains a plurality of allergy testing applicators, an allergy testing tray and a plurality of allergen bottles each containing an allergen. Each of the applicators contains an elongated handle, a plurality of arms extending from the elongated handle and disposed in an asymmetrical configuration, and a plurality of legs with tines extending from each of the arms. The allergy testing tray contains a main body having an underside and a top surface, a cover for locking with the main body and a plurality of reservoirs extending from the underside of the main body. The reservoirs each have a chamber with an opening extending from the top surface. The reservoirs are disposed in different groups and each group has an asymmetrical configuration matching that of the applicator. 1. An allergy skin testing applicator , comprising:an elongated handle;a plurality of arms extending from said elongated handle, said plurality of arms having an asymmetrical configuration wherein said arms are disposed on opposite sides of said elongated handle except for an odd numbered arm being disposed on a center line of said elongated handle and offset from said arms situated on said opposite sides of said elongated handle; anda plurality of legs each having tines and a respective one of said legs extending from a respective one of said arms.2. The allergy skin testing applicator according to claim 1 , wherein a number of said arms or said legs is an odd number selected from the group consisting of 3 claim 1 , 5 claim 1 , 7 claim 1 , 9 and 11.3. The allergy skin testing applicator according to claim 1 , wherein said elongated handle has a first end and a second end defined along a longitudinal extent of said elongated handle claim 1 , said odd numbered arm extends directly from a distal end of one of said first or second ends.4. The allergy skin testing applicator according to claim 1 ,wherein said elongated handle has long sides and shorter sides both extending in a ...

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Номер записи: 58

07-01-2021 дата публикации

Acquisition of Samples for Evaluating Bacterial Demographics

Номер: US20210000453A1

Автор: Nejad Hojatollah Rexaei, Sonkusale Sameer

Принадлежит:

A gut rover traverses the guy and collects samples of the microbiome in a way that permits correlation of samples with particular locations from which they were sampled. 1. An apparatus comprising a gut rover that is configured to traverse a gut , said gut rover comprising a sampler for obtaining samples of the microbiome at selected locations within said gastrointestinal system.2. The apparatus of claim 1 , wherein said sampler comprises an osmotic sampler in which an osmotic pressure differential across a membrane drives sampling.3. The apparatus of claim 1 , wherein said sampler comprises a brine reservoir claim 1 , a semi-permeable membrane claim 1 , and a collection chamber that is in fluid communication with an inlet through which fluid within the gut can enter said gut rover claim 1 , and wherein said semi-permeable membrane separates said brine reservoir from said collection chamber.4. The apparatus of claim 1 , wherein said sampler comprises an oil reservoir claim 1 , a back channel claim 1 , and an elastic membrane wherein said elastic membrane separates a brine reservoir from said oil reservoir claim 1 , and wherein deformation of said elastic membrane increases a level of oil from said oil reservoir in said back channel.5. The apparatus of claim 2 , wherein said sampler is configured to halt sampling upon having collected a pre-defined volume.6. The apparatus of claim 3 , wherein said brine reservoir has a volume that expands during sampling.7. The apparatus of claim 1 , wherein said sampler comprises a thread and nodes along said thread claim 1 , wherein said thread has an end exposed to fluid within said gut.8. The apparatus of claim 1 , wherein said sampler comprises a material that changes shape in response to a trigger.9. The apparatus of claim 1 , wherein said sampler comprises a material that transitions between hydrophobic and hydrophilic states in response to an energy input.10. The apparatus of claim 1 , wherein said sampler comprises tentacles ...

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Номер записи: 59

07-01-2021 дата публикации

COLLECTION DEVICE WITH A VALVE FOR A LIQUID SPECIMEN

Номер: US20210000454A1

Автор: LIN Xiaofeng, LIU Yizhi, LU Lin, LUO Yan

Принадлежит: Zhongshan Ophthalmic Center of Sun Yat-Sen University

Collection devices with valves for liquid specimens are disclosed. In an embodiment, the disclosure provides a collection device including a reservoir having a sealed cavity, the sealed cavity being under a negative pressure; a delivery tube in communication with the sealed cavity of the reservoir and having a delivery inlet, a delivery outlet, and a valve disposed between the delivery inlet and the delivery outlet, the valve being configured to control the communication and blocking between the delivery inlet and the delivery outlet, and an angle being formed by an extension line of the delivery inlet an extension line of the delivery outlet; and a piercing component for piercing a tissue is connected with the delivery inlet of the delivery tube. 1. A collection device with a valve for a liquid specimen , comprising:a reservoir having a sealed cavity, wherein the sealed cavity is under a negative pressure; the valve is disposed between the delivery inlet and the delivery outlet,', 'the valve is configured to control communication and blocking between the delivery inlet and the delivery outlet, and', 'an angle is formed by an extension line of the delivery inlet and an extension line of the delivery outlet; and, 'a delivery tube in communication with the sealed cavity of the reservoir and having a delivery inlet, a delivery outlet, and a valve, whereina piercing component for piercing a tissue and in communication with the delivery inlet of the delivery tube, the valve includes a pressing unit, a rod body connected to the pressing unit, an inner cavity cooperating with the rod body, a first seal ring and a second seal ring separately arranged at different positions on the rod body, and an elastic component provided in the inner cavity;', 'the delivery inlet, the delivery outlet, and the piercing component are in communication when the rod body is at the first position;', 'the delivery inlet is not in communication with the delivery outlet when the rod body is at the ...

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Номер записи: 60

07-01-2021 дата публикации

SCOPE-MOUNTED INOD HANDLE

Номер: US20210000457A1

Автор: "OShaughnessy Seamus F.", Leanna Gary J., LEVENDUSKY JOSEPH A., Powers Michael, Raybin Samuel

Принадлежит:

A handle for a medical device includes a distal portion extending longitudinally and including a distal channel extending therethrough, the distal end of the distal portion including a connector configured to connect to a proximal end of an endoscope, a central portion slidably connected to the distal portion, the central portion extending longitudinally. The handle also includes a central channel extending therethrough, the distal end of the central portion connected to a sheath, the central portion including an introducer port extending laterally therefrom so that an auxiliary tool inserted through the introducer port is directed through a lumen of the sheath. Further, the handle includes a proximal portion slidably connected to the central portion, the proximal portion extending longitudinally and including a proximal channel extending therethrough, the distal end of the proximal portion connected to a needle so that the needle is passed through the lumen. 1. A handle for a medical device , comprising:a central portion with a proximal end and a distal end, the central portion comprising a central channel with a junction and an introducer port, the central channel extending from the proximal end of the central portion to the distal end of the central portion with the junction located proximate the distal end of the central portion, and the introducer port positioned proximal to the junction of the central channel and proximate the proximal end of the central portion, wherein the introducer port is configured to receive an ultrasound probe and direct the ultrasound probe into the central channel and toward the distal end of the central portion; anda proximal portion with a proximal end and a distal end, the distal end of the proximal portion slidably connected to the proximal end of the central portion, the proximal portion comprising a proximal channel aligned with the central channel and extending from the proximal end of the proximal portion to the distal end of ...

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Номер записи: 61

07-01-2016 дата публикации

METHODS FOR MARKING BIOPSY LOCATION

Номер: US20160000414A1

Автор: Brown Andrew E., KLEIN EYAL, LACHMANOVICH ELAD D., SHPINER TATYANA, Weingarten Oren P.

Принадлежит:

Methods, systems, and devices for marking the location of a biopsy are disclosed, including loading a navigation plan into a navigation system with the navigation plan including a CT volume generated from a plurality of CT images, inserting a probe into a patient's airways with the probe including a location sensor in operative communication with the navigation system, registering a sensed location of the probe with the CT volume of the navigation plan, selecting a target in the navigation plan, navigating the probe and location sensor to the target, storing a position of the location sensor in the navigation system as a biopsy location, and performing a biopsy at the stored biopsy location. 1. A method for marking a biopsy location in a patient's airways , the method comprising:loading a navigation plan into a navigation system, the navigation plan including a CT volume generated from a plurality of CT images;inserting a probe into a patient's airways, the probe including a location sensor in operative communication with the navigation system;registering a sensed location of the probe with the CT volume of the navigation plan;selecting a target in the navigation plan;navigating the probe and location sensor to the target;storing a position of the location sensor in the navigation system as a biopsy location; andperforming a biopsy at the stored biopsy location.2. The method according to claim 1 , further comprising placing a virtual marker corresponding to the biopsy location in at least one of a 3D model of the patient's airways generated from the CT volume or a local view of the patient's airways generated from a slice of the CT volume.3. The method according to further comprising inserting the probe through an extended working channel.4. The method of according to claim 3 , further comprising locking the probe relative to the extended working channel.5. The method of claim 4 , further comprising inserting the extended working channel and probe into a ...

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Номер записи: 62

07-01-2016 дата публикации

MULTIPLE-TISSUE FNA SAMPLING

Номер: US20160000415A1

Автор: Belsky Ziv, Hizkiyahu Gilad, LACHTER Jesse

Принадлежит:

An apparatus, device and method are provided for endoscopically extracting multiple tissue samples from multiple locations without needing to completely retract the apparatus or device from the target tissue in the process. In some embodiments the device includes a sheath for delivering the device through a body lumen wall, an outer needle, an inner needle extendable from and retractable into the outer needle, the inner needle having a rotational feature to enable sequential entry of the inner needle at multiple angles relative to the outer needle; and a rotational control mechanism for controlling rotation of the inner needle thereby enabling tissue extraction from multiple locations in a target tissue, without sequentially exiting the body lumen wall. 1. A device for endoscopically extracting multiple tissue samples sequentially froma subject, comprising:a sheath for delivering the device through a body lumen wall;an outer needle;an inner needle extendable from and retractable into said outer needle, said inner needle having a rotational feature to enable sequential entry of said inner needle at multiple angles relative to said outer needle; anda rotational control mechanism for controlling rotation of said inner needle thereby enabling tissue extraction from multiple locations in a target tissue, without sequentially exiting said body lumen wall.2. The device as claimed in claim 1 , wherein the rotational control mechanism is located on a base associated with the outer needle.3. The device as claimed in claim 1 , wherein the inner needle is comprised of a shape memory material such that it forms a pre-configured line of curvature when extended from the outer needle.4. A device as claimed in claim 3 , wherein the sheath claim 3 , outer needle and/or inner needle are flexible enough to be suitable to be delivered endoscopically.5. A device as claimed in claim 3 , wherein the outer needle is adapted to maintain the inner needle in a straight configuration when ...

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Номер записи: 63

02-01-2020 дата публикации

MENSTRUAL CYCLE TRACKING

Номер: US20200000441A1

Автор: Beattie Zachary Todd, Dess Peter Colin, Farjadian Amir Bahador, Ghoreyshi Atiyeh, Heneghan Conor Joseph, Lafon Belen, Niehaus Logan, Sarantos Chris H., Wasson Jaclyn Leverett, Wu Allison Shih

Принадлежит:

Health information for a woman can be used to predict timing of events related to the woman's menstrual cycle. If available, historical cycle information for a woman can be used to predict upcoming cycle events, such as the start and stop of menstruation. To improve the accuracy of those predictions, one or more health metrics are monitored for the woman that can be correlated with the menstrual cycle. These can include, for example, the resting heart rate (RHR), blood oxygen concentration (SpO) level, and hemoglobin concentration, among other such options. The metrics are monitored over time to determine patterns that can be correlated with menstrual cycle. This information can then be used to update the predictive model, as well as to update individual event predictions. Information about the predictions, and updates to the predictions, can be surfaced accordingly. 1. A computer-implemented method , comprising:obtaining, using a non-invasive measurement sub-system of a monitoring device worn by a user, heart rate-derived data for the user over a period of time;obtaining, using the non-invasive measurement sub-system, hemoglobin data for the user over the period of time;analyzing the heart rate-derived data and the hemoglobin data to determine a health pattern for the user;correlating events for a menstrual cycle of the user with features in the health pattern to generate a model for the menstrual cycle;generating, using the model, one or more determinations for events for the menstrual cycle of the user; andproviding, for display, information about the one or more determinations.2. The computer-implemented method of claim 1 , further comprising:receiving, from the user, a selection of one or more types of events for which to receive the information, the types of events including occurrences of menstruation or ovulation.3. The computer-implemented method of claim 1 , further comprising:receiving indication of an occurrence of an event associated with the menstrual ...

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Номер записи: 64

02-01-2020 дата публикации

SYSTEM AND METHOD FOR SELECTING A PATIENT POSITION AND AN EQUIPMENT CONFIGURATION FOR A MEDICAL PROCEDURE

Номер: US20200000442A1

Автор: SANTI KARIMA, Vancamberg Laurence

Принадлежит: GENERAL ELECTRIC COMPANY

A system for selecting a patient position and an equipment configuration for a medical procedure is provided. The system includes a controller, and a memory device operative to store an application. The application adapts the controller to retrieve, from the memory device, one or more possible patient positions for the medical procedure and one or more possible equipment configurations for the medical procedure. The application further adapts the controller to select, based at least in part on one or more parameters of the medical procedure, a patient position from the possible patient positions and an equipment configuration from the possible equipment configurations; and to generate an indicator that conveys the selected patient position and the equipment configuration. 1. A system for selecting a patient position and an equipment configuration for a medical procedure , the system comprising:a controller; and retrieve, from the memory device, one or more possible patient positions for the medical procedure and one or more possible equipment configurations for the medical procedure;', 'select, based at least in part on one or more parameters of the medical procedure, a patient position from the possible patient positions and an equipment configuration from the possible equipment configurations; and', 'generate an indicator that conveys the selected patient position and the equipment configuration., 'a memory device operative to store an application that adapts the controller to2. The system of claim 1 , wherein the one or more parameters of the medical procedure include at least one of:room configuration data;patient physiology data; andmedical device data.3. The system of claim 1 , wherein the medical procedure is a breast biopsy.4. The system of claim 3 , wherein the one or more possible patient positions include at least one of sitting and recumbent.5. The system of claim 3 , wherein the possible equipment configurations include an approach angle for a biopsy ...

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Номер записи: 65

02-01-2020 дата публикации

BIOPSY NEEDLE GUIDE WITH POINTER FOR SIMPLIFIED ANGULATION

Номер: US20200000443A1

Автор: NORAS Hubert

Принадлежит:

Biopsy needle guide with pointer for performing a biopsy in a tissue of a patient in conjunction with an imaging method for imaging the tissue and identification of a target volume to be examined, comprising a needle guide head (), which is freely movable in a plane via at least two degrees of freedom and is mounted so as to be movable about an axis (S) that does not stand perpendicular to this plane, and has a needle passage opening (), a marker pin (), which can be inserted in an opening () of the head () and contains a marker part (), which can be imaged by the imaging method with good contrast, wherein, when the marker pin () is inserted in the opening (), the marker part () lies in the pivot axis (S) of the head (), as well as a use of such a biopsy needle guide. 1. A biopsy needle guide with pointer for performing a biopsy in a tissue of a patient in conjunction with an imaging method for imaging the tissue and identification of a target volume to be examined , comprising:a needle guide head, which is freely movable in a plane via at least two degrees of freedom and is mounted so as to be pivotable about an axis that does not stand perpendicular to this plane, and has a needle passage opening, anda marker pin, which can be inserted in the opening of the head and contains a marker part, which can be imaged by the imaging method with good contrast,wherein when the marker pin is inserted in the opening of the head, the marker part lies in the pivot axis of the head.2. The biopsy needle guide according to claim 1 , wherein in the head a plurality of openings suitable for inserting the marker pin are present claim 1 , of which at least two have an intersection point with the pivot axis of the head.3. The biopsy needle guide according to claim 2 , characterised in that an adapter sleeve inserted into the opening is present.4. The biopsy needle guide according to claim 1 , wherein in a sectional plane claim 1 , the marker part has a cross-shaped or cross-hair-shaped ...

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Номер записи: 66

02-01-2020 дата публикации

BIOPSY DEVICE WITH STERILE SLEEVE

Номер: US20200000444A1

Автор: Nock Andrew Paul, Rhad Edward A., Robinson Andrew

Принадлежит:

A sterile cover assembly is for a biopsy device. The biopsy device includes a reusable holster including a housing and driving mechanism. The driving mechanism is for driving a cutter in a needle of a probe. The housing is adapted to releasably couple to the probe. The sterile cover assembly includes a sleeve and a flexible sterile cover. The sleeve is configured to receive at least a portion of the housing of the reusable holster. The sterile cover is coupled to the sleeve and is configured to cover the housing of the holster. 120-. (canceled)21. A protective cover for use with an article , the protective cover comprising:a flexible cover having a closed end; anda retainer ring configured to retain a part of the flexible cover on an outer surface of the retainer ring with the flexible cover in a folded configuration.22. The protective cover of claim 21 , wherein the retainer ring includes a body defining a slot claim 21 , wherein the slot is configured to permit a portion of the body to fold onto itself.23. The protective cover of claim 22 , wherein the retainer ring further includes an interlocking portion disposed on each side of the slot claim 22 , wherein the interlocking portion is configured to provide rigidity at the slot when each side of the slot is engaged with the other.24. The protective cover of claim 22 , wherein the retainer ring further includes an interlocking portion disposed on each side of the slot claim 22 , wherein the interlocking portion is configured to provide rigidity at the slot when each side of the slot is engaged with the other claim 22 , wherein the interlocking portion includes a tongue and groove configuration.25. The protective cover of claim 22 , wherein the body is a polymer material having a thickness configured to provide at least some flexibility.26. The protective cover of claim 21 , wherein retainer ring is configured to collapse onto itself to transition to a reduced diameter configuration for folding of the flexible cover ...

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Номер записи: 67

02-01-2020 дата публикации

DEVICES AND METHODS FOR SOFT TISSUE BIOPSY AND TISSUE SAMPLE COLLECTION

Номер: US20200000445A1

Автор: Vetter James W.

Принадлежит:

A device comprises an outer tube defining a longitudinal axis and comprising an aperture near a distal end thereof; a cutting element disposed within the outer tube and configured for rotation and movement across the aperture along the longitudinal axis, the cutting element comprising an engagement feature at a distal end thereof; and a distal tip comprising a tapered distal end and a proximal end that comprises a mating feature. The cutting element may be configured to rotate and cut tissue as it moves along the longitudinal axis across the aperture until the engagement feature at least partially engages the mating feature of the proximal end of the distal tip and entrains the distal tip in oscillation along the longitudinal axis and/or rotation. 1. A device , comprising:an outer tube defining a longitudinal axis and comprising an aperture near a distal end thereof;a cutting element disposed within the outer tube and configured for rotation and movement across the aperture along the longitudinal axis, the cutting element comprising an engagement feature at a distal end thereof; anda distal tip comprising a tapered distal end and a proximal end that comprises a mating feature, wherein the cutting element is configured to rotate and cut tissue as it moves along the longitudinal axis across the aperture until the engagement feature at least partially engages the mating feature of the proximal end of the distal tip and entrains the distal tip in at least one of oscillation along the longitudinal axis and rotation.2. The device of claim 1 , further comprising a rotatable element coupled to the distal tip claim 1 , the rotatable element enabling the distal tip to at least rotate independently of the outer tube.3. The device of claim 1 , wherein the distal tip is threaded.4. The device of claim 1 , wherein at least one of the engagement feature at the distal end of the cutting element and the mating feature at the proximal end of the distal tip are configured to enable ...

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Номер записи: 68

02-01-2020 дата публикации

BIOPSY DEVICE HAVING INTEGRATED VACUUM

Номер: US20200000446A1

Автор: Schlarb Rory M., Van Liere Chad C.

Принадлежит:

A biopsy device includes a housing body, and a cannula assembly that has a first elongate cannula and a second elongate cannula coaxial with the first elongate cannula. The second elongate cannula has a lumen and a side wall having a vacuum side port in fluid communication with the lumen. A vacuum source is positioned in the housing body. The vacuum source has a chamber side wall having a chamber vacuum port. A seal is interposed in sealing engagement between the chamber vacuum port and the second elongate cannula. A trigger slide assembly is coupled to the housing body, and coupled to the cannula assembly, and is configured to move the second elongate cannula to align the vacuum side port of the second elongate cannula with the chamber vacuum port of the vacuum source to supply vacuum from the vacuum source to the lumen of the second elongate cannula. 1. A biopsy device , comprising:a housing body defining a longitudinal axis;a cannula assembly having a first elongate cannula having a first side wall configured to define a first lumen and an elongate side opening that extends through the first side wall, and a second elongate cannula coaxial with the first elongate cannula, the second elongate cannula having a second side wall configured to define a second lumen and a cutting edge, the second side wall having a vacuum side port in fluid communication with the second lumen;a vacuum source positioned in the housing body, the vacuum source having a chamber side wall having a chamber vacuum port, the vacuum source having a seal interposed in sealing engagement between the chamber vacuum port and the second elongate cannula; anda trigger slide assembly coupled to the housing body, and coupled to the cannula assembly, and configured to move the second elongate cannula to align the vacuum side port of the second elongate cannula with the chamber vacuum port of the vacuum source to supply vacuum from the vacuum source to the second lumen of the second elongate cannula.2. ...

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Номер записи: 69

03-01-2019 дата публикации

A SKIN PATCH

Номер: US20190000427A1

Автор: Findlay Ewan, MURRAY Sara

Принадлежит:

The application relates to a chemical monitoring system comprising a skin patch for detecting an analyte in perspiration and a processor adapted to receive parameter data and to return an output indicative of a presence of an analyte in a subject's body based on the parameter data. The skin patch () includes a first layer () permeable to perspiration; a second layer () coupled to the first layer, the second layer being adapted to receive the perspiration; wherein a property of the second layer changes upon receiving the analyte; an electrical detector coupled to the second layer, adapted to detect parameter data indicative of the property o f the second layer; and a flexible electronic circuit () coupled to the second layer, comprising a readout circuit for reading parameter data from the electronic detector and a transmitter adapted to transmit the parameter data to a processor. 130-. (canceled)31. A chemical monitoring system comprising:a skin patch for detecting ethanol in perspiration, comprising a first layer permeable to perspiration; a second layer coupled to the first layer, the second layer being adapted to receive the perspiration; wherein a property of the second layer changes upon receiving ethanol; wherein the second layer is made at least in part of a film or matrix comprising Alcohol Oxidase; and an electrical detector coupled to the second layer, adapted to detect parameter data indicative of the property of the second layer; andthe system further comprising a processor adapted to receive the parameter data and to return an output indicative of a presence of ethanol in a subject's body based on the parameter data.32. The chemical monitoring system as claimed in claim 31 , comprising a housing comprising communication means; optionally wherein the housing is removably coupled to the skin patch.33. The chemical monitoring system as claimed in claim 32 , wherein the processor is located within the housing or wherein the processor is located in a device ...

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Номер записи: 70

03-01-2019 дата публикации

ASPIRATION FILTRATION DEVICE

Номер: US20190000428A1

Автор: Gray Jeff, KENWOOD SHANNON SMITH, SCOTT Serena, STORBECK Gene T.

Принадлежит: BOSTON SCIENTIFIC SCIMED, INC.

A tissue filtration device may include an elongate hollow needle assembly having open distal and proximal ends. In some cases, the tissue filtration device may include a collection device containing a filter material and coupled to the elongate hollow needle assembly and in fluid communication with the elongate hollow needle. Also included may be a suction assembly coupled to the collection device and configured to draw fluid from the elongate hollow needle assembly into the collection device. 1. A tissue filtration device , comprising:a distal elongate hollow needle comprising a needle lumen with distal and proximal ends;a collection device fluidly coupled to the needle lumen comprising a filter material; anda proximal assembly configured to draw fluid from the needle lumen into the collection device.2. The tissue filtration device of claim 1 , wherein the distal elongate hollow needle includes an elongate hollow needle and a hollow tube proximal of the elongate hollow needle.3. The tissue filtration device of claim 1 , wherein the proximal assembly includes a handle and a hollow tube distal of the handle.4. The tissue filtration device of claim 3 , wherein the handle includes a piston inside a cylindrical tube and the fluid is drawn from the needle lumen of the distal elongate hollow needle to the collection device by moving the piston through the cylindrical tube.5. The tissue filtration device of claim 3 , wherein the handle includes a mechanism and the fluid is drawn from the needle lumen of the distal elongate hollow needle to the collection device by actuating the mechanism.6. The tissue filtration device of claim 1 , wherein the filter material filters tissue from the fluid.7. The tissue filtration device of claim 1 , wherein the filter material includes a filter membrane.8. The tissue filtration device of claim 1 , wherein the collection device comprises an exterior casing configured to maintain an airtight seal when punctured by the distal elongate hollow ...

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Номер записи: 71

03-01-2019 дата публикации

DIAGNOSIS AND TREATMENT OF TISSUE

Номер: US20190000430A1

Автор: Jasion Edward A., Tehrani Amir

Принадлежит:

A method of evaluating an image indicating a potential presence of a cancer lesion at a location within a prostate of a patient by transmitting light from an optical probe toward a location, receiving fluorescence spectra by the optical probe from the location, and generating a visual display of a diagnosis classification so as to confirm or contradict the existence of the cancer lesion at the location. 1. A method of evaluating an image indicating a potential presence of a cancer lesion at a location within a prostate of a patient , the method comprising:positioning an optical probe so as to target the location within the prostate of the patient;transmitting light from the optical probe toward the location and receiving fluorescence spectra by the optical probe from the location which is utilized by a tissue classification system having at least one algorithm that generates a diagnosis classification based only on selected data of the fluorescence spectra; andgenerating a visual display of the diagnosis classification at the location overlapping the image so as to confirm or contradict the existence of the cancer lesion at the location.2. A method as in claim 1 , wherein the image comprises an MRI image claim 1 , an ultrasound image claim 1 , a CT image or an MM image.3. A method as in claim 1 , wherein the image comprises an MRI/US fusion image.4. A method as in claim 1 , wherein the diagnosis classification is visualized on the visual display by a color indicating the diagnosis classification.5. A method as in claim 1 , further comprising selecting a view for the visual display wherein the view comprises a two-dimensional image or a three-dimensional image.6. A method as in claim 1 , further comprising selecting an option for the visual display claim 1 , wherein the option comprises a black-and-white image claim 1 , a color image claim 1 , and/or a line image.7. A method as in claim 1 , wherein positioning the probe comprises introducing the probe under ...

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Номер записи: 72

04-01-2018 дата публикации

BIOPSY SAMPLE CONTAINER

Номер: US20180000463A1

Автор: Keller Bryan R.

Принадлежит:

An apparatus for individually storing multiple tissue samples separately from each other includes a base, a lid, a lock, and one or more vents. The base defines a plurality of reservoirs and a plurality of identification areas. A portion of the base defines an opening corresponding to each reservoir. The lid is configured to secure the multiple tissue samples within a corresponding reservoir by enclosing each corresponding opening in the closed configuration. The lock is configured to selectively lock the lid against the base in the closed configuration. The one or more vents are configured to enable entry of fluid into the reservoirs when the lid is in the closed configuration. The one or more vents are further configured to prevent exit of tissue samples from the reservoirs when the lid is in the closed configuration. 1. An apparatus for individually storing multiple tissue samples separately from each other , the apparatus comprising:(a) a base defining a plurality of reservoirs, wherein a portion of the base defines a plurality of openings with each opening associated with a corresponding reservoir;(b) a lid configured to transition between an open configuration and a closed configuration, wherein the lid is configured to secure each tissue sample of the multiple tissue samples within a corresponding reservoir by enclosing each corresponding opening in the closed configuration;(c) a plurality of identification areas, wherein each identification area of the plurality of identification areas is associated with the base or the lid;(d) a lock, wherein the lock is configured to selectively lock the lid against the base in the closed configuration; and(e) one or more vents, wherein the one or more vents are configured to enable entry of fluid into the reservoirs when the lid is in the closed configuration, wherein the one or more vents are sized sufficiently small to prevent exit of tissue samples from the reservoirs when the lid is in the closed configuration.2. The ...

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Номер записи: 73

04-01-2018 дата публикации

INTEGRATED PAINLESS BONE MARROW BIOPSY DEVICE

Номер: US20180000465A1

Автор: BROWN Elliott, FRIEDMAN Tamir

Принадлежит:

An apparatus and method for performing painless bone marrow biopsy that requires only a single procedural pass to the biopsy bone site is disclosed. The biopsy device combines dermatotomy, anesthesia and marrow specimen extraction functionality and inherently aligns the bone drilling site with the site of anesthetic delivery by incorporating a transport channel that may be used for anesthetic delivery, into the biopsy needle used for bone access and bone marrow sample retrieval. The biopsy device also discloses a right angle drill interface and multiple side-access ports for aspiration and anesthetic syringe attachments. A novel syringe/plunger system comprising vacuum tube fitted plungers for quick transfer of marrow specimen sample without requiring a second non-sterile assistant is also disclosed. 1. A device comprising:a needle assembly comprising:a hollow tubular sleeve having a hollow opening therethrough,a stylet mounted in the hollow opening of the hollow tubular sleeve and having a first conduit therethrough, andone or more side openings,a liquid pressure generator in fluid communication with the first conduit and configured to apply pressure to liquid in the first conduit,wherein when a container containing a liquid anesthetic agent is in fluid communication with the first conduit and the liquid pressure generator applies pressure to the liquid anesthetic agent, the liquid anesthetic agent is forced through the first conduit and out through one or more end-openings of the stylet, andwherein when the device is inserted in bone marrow so that side openings are exposed to the bone marrow and a suction generator applies suction to a second conduit extending at least partway through the needle assembly, at least a portion of the bone marrow is withdrawn into the device through the side openings.2. The device of claim 1 , wherein the first conduit and second conduit are different conduits.3. The device of claim 1 , wherein the stylet includes a removable distal ...

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Номер записи: 74

04-01-2018 дата публикации

ADJUSTABLE-BENDING STIFFNESS STEERABLE NEEDLE, BUCKLING-PREVENTING STEERABLE NEEDLE, AND STEERABLE NEEDLE SYSTEM INCLUDING SAME

Номер: US20180000466A1

Автор: Kang Byungjeon, PARK Jongoh, PARK Sukho

Принадлежит: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY

Disclosed herein are an adjustable-bending stiffness steerable needle, a buckling-preventing steerable needle, and a steerable needle system including the same. The adjustable-bending stiffness steerable needle includes a cylindrical core wire, a tip portion, a needle shaft, a compression spring, and a rigid shaft. The tip portion has a bevel shape, and is connected to the front end of the core wire. The needle shaft is disposed such that one end thereof is separable from the tip portion and the needle shaft surrounds the core wire. The compression spring is fastened to the other end of the needle shaft, and is configured such that the core wire passes therethrough. The rigid shaft is connected to the core wire having passed through the compression spring, and is also connected to the compression spring. The needle shaft includes a plurality of hollow tube elements that is separable from each other. 1. An adjustable-bending stiffness steerable needle , comprising:a cylindrical core wire;a tip portion configured to have a bevel shape, and connected to a front end of the core wire;a needle shaft disposed such that one end thereof is separable from the tip portion and the needle shaft surrounds the core wire;a compression spring fastened to a remaining end of the needle shaft, and configured such that the core wire passes therethrough; anda rigid shaft connected to the core wire having passed through the compression spring, and also connected to the compression spring;wherein the needle shaft includes a plurality of hollow tube elements that are separable from each other.2. The adjustable-bending stiffness steerable needle of claim 1 , wherein the tip portion has a cone-shaped permanent magnet claim 1 , steerable by an external magnetic field generation mechanism claim 1 , instead of the bevel shape.3. The adjustable-bending stiffness steerable needle of claim 1 , wherein at least one of both ends of the compression spring is configured to be slidable along an outer ...

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Номер записи: 75

07-01-2016 дата публикации

VIRTUAL RIGID BODY OPTICAL TRACKING SYSTEM AND METHOD

Номер: US20160000516A1

Автор: Boctor Emad M., Cheng Alexis, Guo Xiaoyu

Принадлежит:

A virtual rigid body optical tracking system includes a virtual rigid body generator for projecting a virtual rigid body, wherein the virtual rigid body forms a pattern of light on a surface. The virtual rigid body optical tracking system includes an optical detection system for detecting the pattern of light, and a data processing system in communication with the optical detection system. The data processing system is configured to determine a position of the virtual rigid body generator based on the detected pattern of light. 1. A virtual rigid body optical tracking system , comprising:a virtual rigid body generator for projecting a virtual rigid body, wherein said virtual rigid body forms a pattern of light on a surface;an optical detection system for detecting said pattern of light; anda data processing system in communication with said optical detection system,wherein said data processing system is configured to determine a position of said virtual rigid body generator based on said detected pattern of light.2. A virtual rigid body optical tracking system according to claim 1 , wherein said data processing system is further configured to reconstruct said virtual rigid body based on said detected pattern of light claim 1 , and wherein said determination of said position of said virtual rigid body generator is based on said reconstructed virtual rigid body.3. A virtual rigid body optical tracking system according to claim 1 , wherein said virtual rigid body generator is attached to a tool claim 1 , andwherein said data processing system is configured to determine a position of said tool based on said detected pattern of light.4. A virtual rigid body optical tracking system according to claim 3 , wherein said data processing system is further configured to determine an orientation of said tool based on said detected pattern of light.5. A virtual rigid body optical tracking system according to claim 1 , wherein said virtual rigid body generator comprises a ...

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Номер записи: 76

07-01-2021 дата публикации

Methods and systems for controlled deployment of needles in tissue

Номер: US20210000565A1

Автор: Jordan Bajor, Malcolm G. Munro, Michael Munrow

Принадлежит: Gynesonics Inc

Needles are deployed in tissue under direct ultrasonic or other imaging. To aid in deploying the needle, a visual needle guide is projected on to the image prior to needle deployment. Once the needle guide is properly aligned, the needle can be deployed. After needle deployment, a safety boundary and treatment region are projected on to the screen. After confirming that the safety boundary and treatment regions are sufficient, the patient can be treated using the needle.

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Номер записи: 77

05-01-2017 дата публикации

Tissue biopsy device with selectively rotatably linked thumbwheel and tissue sample holder

Номер: US20170000465A1

Автор: Edward A. Rhad, Jessica Pyzoha Leimbach, John Scott EHLERT, Morgan Robert Hunter

Принадлежит: Devicor Medical Products Inc

A biopsy system comprising a probe and a holster. The probe comprises a rotatable needle portion a rotatable thumbwheel coupled with the needle portion and a rotatable tissue sample manifold. The holster is removably coupled to the probe. The holster comprises a selective engagement mechanism configured to selectively link rotation of the thumbwheel with rotation of the tissue sample manifold. A method of collecting tissue samples using a biopsy system unlinking rotation of the thumbwheel with rotation of the tissue sample manifold by actuating the selective engagement mechanism; and obtaining a tissue sample after the unlinking.

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Номер записи: 78

05-01-2017 дата публикации

Biopsy device with aspiration valve

Номер: US20170000466A1

Автор: Carl Pierce, Christian M. Ulm, Daniel Robertson, Joseph A. STAND, III, Peter Wolton, Thomas Fisk

Принадлежит: Hologic Inc

A biopsy device includes an instrument set and an instrument drive unit removably coupled to the instrument set. The instrument set includes an instrument set housing; an elongate outer cannula having a tissue receiving aperture in a side wall thereof; an elongate inner cannula disposed within an outer cannula lumen; an aspiration vent fluidly coupling the outer cannula lumen to atmosphere; and an aspirate valve in the aspiration vent, and configured such that the outer cannula lumen is vented to atmosphere only when the aspirate valve is open. The instrument drive unit includes a drive unit support structure removably coupled to the instrument set housing; a motorized inner cannula driver configured to axially oscillate the inner cannula relative to the outer cannula to sever tissue extending through the tissue receiving opening; and an actuating member configured to selectively mechanically prevent the aspirate valve from closing.

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Номер записи: 79

05-01-2017 дата публикации

CUTTER DRIVE ASSEMBLY FOR BIOPSY DEVICE

Номер: US20170000467A1

Автор: Hibner John A., Mescher Patrick A., Rhad Edward A.

Принадлежит:

A biopsy device comprises a body, a needle, and a cutter actuation mechanism. The needle extends distally from the body. The cutter actuation mechanism rotates and translates the cutter relative to the body and relative to the needle. The cutter has an overmold presenting a lead screw and a hex portion. The cutter actuation mechanism comprises a first gear disposed about the hex portion of the overmold and a second gear engaged with the lead screw of the overmold by a nut that is integral with the second gear. The cutter actuation mechanism is operable to simultaneously rotate the first gear relative to the body at a first rotational speed and the second gear relative to the body at a second rotational speed. With the lead screw and the nut rotating at different rotational speeds, the lead screw rotates relative to the nut at a third rotational speed. 120.-. (canceled)21. A biopsy device , comprising:(a) a body;(b) a needle extending distally relative to the body, wherein the needle defines a first lumen and a second lumen, wherein the first lumen and second lumen are separated by a wall extending through at least a portion of the needle, wherein the needle includes an opening fluidly coupling the first lumen with the second lumen;(c) a cutter, wherein the cutter is configured to translate relative to the needle to sever tissue; and(d) a member operable to translate in conjunction with the cutter, relative to an external housing, through a first range of motion of the cutter, wherein the member is operable to remain in a stationary position relative to the cutter through a second range of motion, and wherein the member is movable from a venting position to a sealing position when the member translates in conjunction with the cutter.22. The biopsy device of claim 21 , wherein the member is coaxially disposed about the cutter.23. The biopsy device of claim 21 , wherein the first lumen of the needle extends along a first longitudinal axis claim 21 , wherein the second ...

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Номер записи: 80

05-01-2017 дата публикации

BIOPSY DEVICE WITH INTEGRAL VACUUM ASSIST AND TISSUE SAMPLE AND FLUID CAPTURING CANISTER

Номер: US20170000468A1

Автор: Hibner John A.

Принадлежит:

A biopsy device includes a body, a probe cannula, a cutter, a vacuum source, a tissue sample holder, and a flexible tube. The probe cannula extends distally from the body and defines an internal passage with a side aperture. The cutter is translatable relative to the probe cannula to sever a tissue sample received in the probe cannula. The vacuum source is in communication with the cutter. The tissue sample holder includes a vacuum port on the exterior surface to communicate with the vacuum source and a removable portion to hold solid tissue samples. The removable portion is selectively removable from the tissue sample holder and includes a straining member to separate fluids from solids. The flexible tube couples the tissue sample holder with the body such that the tissue sample holder is flexibly spaced away from the body. 120-. (canceled)21. A biopsy device comprising:(a) a probe cannula defining an internal passage and having a side aperture;(b) a cutter translatable relative to the probe cannula to sever a tissue sample received in the probe cannula;(c) a vacuum source in communication with the cutter;(d) a container, wherein the container comprises a tissue sample holder located in the container, wherein the tissue sample holder is configured to hold solid tissue samples within the container; and(e) a conduit, wherein the conduit is configured to provide fluid communication between the container and a proximal end of the cutter, wherein the conduit is further configured to communicate solid tissue samples from the cutter to the tissue sample holder, wherein at least a portion of the conduit comprises a flexible tube coupling the container with the probe cannula such that the probe cannula is movable relative to the container.22. The biopsy device of claim 21 , wherein the conduit is is proximally held relative to the probe cannula by a tube guide.23. The biopsy device of claim 21 , wherein the conduit defines at least a portion of a fluid passageway.24. The ...

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Номер записи: 81

03-01-2019 дата публикации

ROBOTIC ASSISTED PROSTATE SURGERY DEVICE

Номер: US20190000572A1

Автор: Seifabadi Reza, Squires Alex, Tse Tsz Ho, Wood Bradford, Xu Sheng

Принадлежит:

An example robot system for guiding a percutaneous device into a prostate of a patient includes a guide defining an opening configured to direct the needle, a robot coupled to the guide, and a rotation member coupled to the robot. The robot being configured to move the guide in a left-right and anterior-posterior directions based on information on the prostate of the patient. The rotation member being configured to change a yaw angle of the guide within a coronal plane of the patient. 1. A robotic system for guiding a needle into a prostate of a patient , the system comprising:a guide defining an opening configured to direct the needle;a robot coupled to the guide and configured to move the guide in a left-right and anterior-posterior directions based on information on the prostate of the patient; anda rotation member coupled to the robot and configured to change a yaw angle of the guide within a coronal plane of the patient.2. The system of claim 1 , wherein the rotation member is configured to change the yaw angle about a remote center of motion.3. The system of claim 2 , wherein the remote center of motion is positioned with an axis extending through the prostate.4. The system of claim 2 , wherein the remote center of motion is positioned with an axis inferior or superior to the prostate.5. The system of claim 2 , wherein the yaw angle is +/−15 degrees with respect to a sagittal plane of the patient.6. The system of claim 5 , wherein the rotation member includes a bearing positioned at the remote center of motion.7. The system of claim 6 , further comprising a base plate claim 6 , wherein the rotation member is mounted via the bearing to the base plate and wherein the base plate is configured to be mounted to a table of an MRI.8. The system of claim 7 , wherein the robot is supported above the bearing on one end of the rotation member and the rotation member has another end configured to extend out of a bore of the MRI.9. The system of claim 2 , wherein the ...

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Номер записи: 82

04-01-2018 дата публикации

SURGICAL ROBOT PLATFORM

Номер: US20180000546A1

Автор: Crawford Neil R., Foster Mitchell A., Theodore Nicholas

Принадлежит:

A medical robot system, including a robot coupled to an effectuator element with the robot configured for controlled movement and positioning. The system may include a transmitter configured to emit one or more signals, and the transmitter is coupled to an instrument coupled to the effectuator element. The system may further include a motor assembly coupled to the robot and a plurality of receivers configured to receive the one or more signals emitted by the transmitter. A control unit is coupled to the motor assembly and the plurality of receivers, and the control unit is configured to supply one or more instruction signals to the motor assembly. The instruction signals can be configured to cause the motor assembly to selectively move the effectuator element. 1. A method for automatically maintaining a surgical robot on a planned trajectory , said method comprising:receiving data indicative of an orientation position of an end effector, wherein the orientation position is an orientation axis associated with the end effector;accessing data indicative of one or more joints of the surgical robot;accessing a current camera position of the surgical robot on the planned trajectory, wherein the current position is represented in a camera coordinate system;calculating an orientation of the end effector in a robot coordinate system;calculating a position of the end effector in the robot coordinate system;determining a line defining the planned trajectory in the robot coordinate system; andlocking a position of the surgical robot on the planned trajectory.2. The method of claim 1 , further comprising supplying information indicative of a quality of the locked position of the surgical robot.3. The method of claim 1 , wherein supplying information includes providing aural indicia.4. The method of claim 2 , further comprising determining whether a surgical procedure is finished.5. The method of claim 4 , wherein the planned trajectory is generated by an operator.6. The method ...

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Номер записи: 83

05-01-2017 дата публикации

BIOPSY DEVICE SUPPORT OR HOLDER AND METHOD OF USE

Номер: US20170000578A1

Автор: Lampropoulos Justin, McArthur Gregory R.

Принадлежит:

A support or holder for a biopsy device is disclosed. The support includes a holder section that grasps or otherwise supports the biopsy device, wherein the support may be configured with flexible support members that may be bent, flexed or articulated thereby allowing the practitioner to manipulate the support for re-positioning the biopsy device into a desired position where the biopsy device may then be actuated to acquire a tissue sample. 1. A system for positioning a biopsy device , comprising:a base section;a stanchion having a first end connected to the base section and a second end distal from the base section;a holder section disposed on or attached to the second end of the stanchion, the holder section constructed and arranged for accepting a biopsy device and holding the biopsy device in a desired orientation, wherein the stanchion is flexible for positioning and supporting the holder section in a desired position.2. A system according to wherein the stanchion comprises a plurality of interconnected linkage units extending linearly from the base section to the holder section.3. A system according to wherein the stanchion comprises a plurality of interconnected ball and socket members extending linearly from the base section to the holder section.4. A system according to wherein the base section comprises a disk-shaped plate.5. A system according to further comprising an adhesive or tape on a bottom of the base section for securement to a support surface.6. A system according to wherein the stanchion is an elongated column-like structure.7. A system for positioning a biopsy device claim 1 , comprising:a base section including a top portion and a bottom portion;a leg section including three or more legs, each leg attached to the bottom portion of the base section and extending downward therefrom for providing support for the base section onto a surface or other object;a holder section connected to a top end of the base section, the holder section comprising ...

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Номер записи: 84

04-01-2018 дата публикации

Endoscopic Ultrasound-Guided Biliary Access System

Номер: US20180001057A1

Автор: McWeeney John O.

Принадлежит:

The present disclosure provides an access system having a maneuverable catheter assembly configured for providing access to and navigating a desired vessel for subsequent treatment thereof. The access system includes an adjustable delivery handle assembly and an access catheter subassembly having a maneuverable access catheter configured to be delivered to desired site (e.g., within duodenum) to assist in treatment of a condition (e.g., drainage of a bile ducts via Endoscopic Ultrasound Guided Biliary Drainage (EUS-BD) techniques). The access catheter includes at least a distal section having an adjustable portion along a length thereof configured to transition to a pre-defined arcuate shape to provide directional control over the distal end of the catheter as it is navigated through a vessel (e.g., bile duct). The handle assembly includes additional elements configured to allow a clinician to maneuver and manipulate the distal end of the access catheter. 1. A system for providing access to a vessel , the system comprising: a delivery handle assembly, at least a portion of which comprises an inner lumen configured to receive one of a plurality of exchangeable subassemblies; and', 'an inner hub housing coupled to a portion of the deliver handle assembly, the inner hub housing having a first plurality of radially-spaced barbs disposed on an inner diameter thereof;', 'a sheath coupled to a distal end of the handle assembly and having a lumen in fluid communication with the inner lumen of the delivery handle assembly; and', a catheter hub configured for insertion into the inner hub housing, the catheter hub having a second plurality of radially-spaced barbs disposed on an outer diameter thereof, wherein each of the second plurality of barbs are configured for selective engagement with a corresponding one of the first plurality of barbs to permit incremental rotation of the catheter hub relative to the inner hub housing; and', 'an access catheter having an elongate ...

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Номер записи: 85

04-01-2018 дата публикации

METHODS FOR SAMPLING GINGIVAL METABOLITES

Номер: US20180003598A1

Автор: FIENO Angela Marie, Haught John Christian, HUGGINS, JR. Donald James, JR. Thomas Glenn, KHAMBE Deepa Ashok, Klukowska Malgorzata, Li Lijuan, TANSKY Cheryl Sue, White, Xie Sancai

Принадлежит:

One or more methods for sampling gingival metabolites and biomarkers. 1. A method for non-invasive collection of gingival samples comprising:using a collection device oriented parallel to the gum line of a specific tooth;detaching a portion of the collection device from the collection device and placing into a container;extracting protein and metabolite from the portion of the collecting device.2. The method of wherein the collection device is at least one of an interdental gum brush or buccal brush.3. The method of wherein the container contains extraction buffer.4. The method of wherein the extraction buffer is at least one of Dulbecco's phosphate-buffered saline or RNAlater.5. A method for extraction from gingival brush samples comprising:using a collection device oriented parallel to the gum line of a specific tooth;a portion of the collection device is detached from the collection device and placed into a container containing extraction buffer;removing the collection device from the container; andextracting a biomarker.6. The method of claim 5 , wherein the extracted biomarker is analyzed with analytical procedures that quantify the levels of at least one of metabolite.7. The method of claim 6 , wherein a metabolite is at least one of a metabolite produced by: lipid metabolism claim 6 , protein and amino acid metabolism claim 6 , carbohydrate metabolism claim 6 , nuclear acid metabolism claim 6 , or oxidative phosphorylation.8. The method of claim 6 , wherein the method of analysis is at least one of: immunoassay claim 6 , gradient hydrophilic interaction liquid chromatography with tandem mass spectrometry (HILIC/MS/MS) claim 6 , enzymatic assay; or colorimetric assay.10. The method of claim 6 , wherein the metabolite is at least one of: citrulline claim 6 , ornithine claim 6 , arginine claim 6 , succinate claim 6 , malate and fumarate claim 6 , deoxycarnitine or pyroglutamine.11. The method of claim 6 , wherein the metabolite is at least one of: 13-HODE claim ...

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Номер записи: 86

04-01-2018 дата публикации

METHOD FOR QUANTITATIVE MEASUREMENT OF GASTRIC ACIDITY USING 13C CARBONATE SALT

Номер: US20180003695A1

Автор: Akamatsu Suguru, INADA Makoto, KUNIZAKI Jun-ichi, llZUKA Shinji, TOBITA Kazuki

Принадлежит: OTSUKA PHARMACEUTICAL CO., LTD.

The present invention provides a method for measuring the gastric acidity of a mammal using a C-labeled carbonate compound. Specifically, the present invention relates to a method for measuring the gastric acidity of a mammal including the following steps: 1. A method for measuring an effect of a gastric acid reducer on a mammal , the method comprising the following steps (1) to (4):{'b': '1', 'sup': 13', '13, 'sub': '2', '() using, as a test sample, expired air of a mammalian subject excreted at any point in time within 30 minutes after oral administration of a predetermined amount of a C-labeled carbonate compound, the oral administration being performed after administration of a gastric acid reducer, measuring behavior of COexcreted in the expired air,'}{'sup': 13', '13', '13', '13', '13, 'sub': 2', '2', '2', '2, '(2) comparing the behavior of CO(measured CObehavior) obtained in step (1) with the behavior of corresponding CO(reference CObehavior) measured in a mammal (control mammal) to which a predetermined amount of a C-labeled carbonate compound has been orally administered beforehand without administering the gastric acid reducer;'}{'sup': 13', '13, 'sub': 2', '2, '(3) determining gastric acidity of the mammalian subject based on a difference between the reference CObehavior and the measured CObehavior obtained above; and'}(4) determining the effect of the gastric acid reducer on the mammalian subject using the gastric acidity of the mammalian subject obtained above as an index.2. The method according to claim 1 , wherein the behavior of COis ΔC (‰) obtained from expired air of a mammalian subject collected at any point in time within 30 minutes after oral administration of a C-labeled carbonate compound.3. The method according to claim 1 , wherein the predetermined amount is 10 mg to 5 g.4. The method according to claim 1 , wherein the C—labeled carbonate compound is at least one carbonate compound selected from the group consisting of alkali metal ...

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Номер записи: 87

01-01-2015 дата публикации

Device for Taking at Least One Sample of Tissue

Номер: US20150005663A1

Автор: Callede David, Moine Adrien, Pinaud Denis, Pivard Laurent, Teppe Fabrice

Принадлежит: COLOPLAST A/S

This invention relates to a device () for taking at least one sample of soft tissue from an organ, said device comprising a body () and a needle () formed by a stylet () and a cannula () coaxial with said stylet, said device comprising a mechanism for arming the needle, designed for sequentially moving the cannula () and then the stylet () from a rest position wherein the stylet and the cannula are extended towards the outside of the body, to a shooting position wherein the stylet and the cannula are retracted towards the rear of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position, the cannula being coupled kinematically to a cannula slider () comprising at least one retaining element () for maintaining the cannula slider in a shooting position, the stylet being coupled kinematically to a stylet slider () comprising at least one retaining element () for maintaining the stylet slider in a shooting position and means for unlocking () the cannula slider. At least one of said retaining elements of the cannula slider () or stylet slider () comprises at least a hook () arranged to rest against a corresponding retaining element () in a locking position and to release the retaining element () in a shooting position. The retaining element is unhooked from said retaining means by a striker (), this striker comprising elastic blades () which number is at least equal to the number of hooks of said retaining element, these elastic blades () being arranged to be in contact with said hooks. The striker () cooperates with a stressing ring () arranged around the elastic blades () of the striker (), this stressing ring () being arranged to be movable in a first stressing position, in which said ring acts on the elastic blades () of the striker and forces them in order to allow a sufficient force to be applied to the hooks () of the retaining element, and a second free ...

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Номер записи: 88

01-01-2015 дата публикации

CYTOLOGY BRUSH DEVICES AND METHODS OF USE

Номер: US20150005665A1

Автор: Stanton Larry E., WELDON James

Принадлежит:

According to one aspect of the present disclosure, a cytology brush may include an elongated shaft including a proximal end portion and a distal end portion. The cytology brush may also include a plurality of bristles mounted on the distal end portion of the elongated shaft. The plurality of bristles may be arranged at least partially around the distal end portion of the elongated shaft, and may be configured to engage tissue. An outer surface of at least one of the bristles may include a micropattern formed by a plurality of protrusions or recesses. The plurality of protrusions or recesses may be separated by one or more gaps. 1. A cytology brush , comprising:an elongated shaft including a proximal end portion and a distal end portion; anda plurality of bristles mounted on the distal end portion of the elongated shaft, the plurality of bristles being arranged at least partially around the distal end portion of the elongated shaft and configured to engage tissue;wherein an outer surface of at least one of the plurality of bristles includes a micropattern formed by a plurality of protrusions or recesses, separated by one or more gaps.2. The cytology brush of claim 1 , wherein the plurality of protrusions or recesses are arranged in longitudinally extending columns separated by the one or more gaps claim 1 , and in circumferentially extending rows separated by the one or more gaps.3. The cytology brush of claim 1 , wherein the plurality of protrusions or recesses have one of a rectangular or circular cross-sectional shape.4. The cytology brush of claim 1 , wherein the protrusions or recesses have a width between approximately 10 and 20 micrometers claim 1 , and each of the one or more gaps has a width of between approximately 10 and 20 micrometers.5. The cytology brush of claim 1 , wherein the micropattern is configured to exert a holding force on cells from the tissue when the bristles engage the tissue.6. The cytology brush of claim 1 , wherein the plurality of ...

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Номер записи: 89

01-01-2015 дата публикации

ENDOMETRIAL SAMPLE COLLECTOR

Номер: US20150005667A1

Автор: Zavala Carlos Fidel Miranda

Принадлежит:

A non-invasive endometrial sample collector has an outer body of absorbent material configured for insertion into a vaginal cavity of a patient such that a distal end of the body is positioned proximate a uterine cervix of the patient. The collector has an internal collection assembly disposed within the outer body of absorbent material. The internal collection assembly includes a funnel having an opening at the distal end of the outer body configured to face the uterine cervix when the outer body is positioned in the vaginal cavity, and a reservoir in fluid communication with the funnel. During a menstruation cycle of the patient when endometrial tissue cells are shed within menstrual fluid that passes through the uterine cervix, or during any type of normal or abnormal bleeding episode, at least a portion of said fluid is directed to the reservoir via the funnel under the force of gravity. 1. An endometrial sample collector , comprising:an outer body of absorbent material configured for insertion into a vaginal cavity of a patient such that a distal end of the body is positioned proximate a uterine cervix of the patient; and a funnel having an opening at the distal end of the outer body configured to face the uterine cervix when the outer body is positioned in the vaginal cavity, and', 'a reservoir in fluid communication with the funnel,, 'an internal collection assembly disposed within the outer body of absorbent material, the internal collection assembly comprising'}wherein during a menstruation cycle of the patient when endometrial tissue cells are shed within menstrual fluid that passes through the uterine cervix, at least a portion of said menstrual fluid is directed to the reservoir via the funnel under the force of gravity.2. The endometrial sample collector of claim 1 , further comprising a conduit interposed between and in fluid communication with the funnel and reservoir.3. The endometrial sample collector of claim 2 , wherein the conduit comprises a ...

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Номер записи: 90

01-01-2015 дата публикации

SURGICAL INSTRUMENT

Номер: US20150005813A1

Автор: Maslanka Herbert, Seitz Sebastian, Steen Henning

Принадлежит: Ruprecht-Karls-Universitat-Heidelberg

The surgical instrument comprises a forceps tool () having a forceps base () and at least two forceps fingers () guided such that they can move relative to one another on the forceps base (), and a manual actuation element for opening and closing the forceps element (). The manual actuation element is connected to the forceps tool () via an elongated, flexible actuation cable () which comprises a tubular, flexible cable sheath () connected to the forceps base () and a flexible cable core () guided displaceably in the cable sheath () and connected to the forceps fingers () for opening and closing the forceps tool (). At least the forceps fingers () of the forceps tool () are made of a non-ferromagnetic or substantially non-ferromagnetic metal, in particular titanium. The cable sheath () and the cable core () are each made of a electrically non-conducting composite material in which a plurality of reinforcing threads () running along the actuation cable () are embedded in a plastics matrix. Such a gripper instrument can also be employed under the operating conditions of a magnetic resonance tomograph. 1. Surgical instrument , comprising:a surgical tool having a tool base and a tool element movably guided relative to the tool base;a manual actuation element for moving the tool element relative to the tool base; andan elongated, flexible actuation cable which connects the manual actuation element to the surgical tool and has a tubular, flexible cable sheath connected to the tool base and a flexible cable core which is guided displaceably in the cable sheath and is connected to the tool element for movement thereof relative to the tool base, wherein at least the tool element of the surgical tool, but, in particular, also the tool base thereof, is made substantially of a non-ferromagnetic or substantially non-ferromagnetic metal or of ceramic or of plastic, and in that the cable sheath and the cable core are each made of an electrically non-conducting or substantially non ...

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Номер записи: 91

05-01-2017 дата публикации

SYSTEM AND METHOD FOR ANTI TEXTING IN CELL PHONES DURING VEHICLE DRIVING

Номер: US20170006151A1

Автор: Doorandish Seyed Mehdi

Принадлежит:

The embodiments herein provide a system and method for enabling anti-texting feature in a cell phone when the cell phone is operated by a driver in a dangerous manner such as text messaging or holding the cell phone to the driver's ear while driving a vehicle. The system creates a green zone or life zone around a driver's seat that controls the driver not to participate in distracting activities while driving a vehicle. The system comprises a sensor module, Bluetooth transmitter, and a Bluetooth receiver installed in driver's cell phone. The Bluetooth transmitters are placed at different locations in vehicle and analyzes the driver behavior while driving the vehicle. The sensor in vehicle monitors the driver behavior and transmits appropriate signals. The Bluetooth receiver receives the signals from the transmitter and disables keypad interface of the driver cell phone through an anti-texting application. 1. A system for preventing anti-texting and making calls by a driver of a vehicle during a vehicle driving condition , the system comprising:a sensor module for detecting a vehicle running condition;a Bluetooth transmitter mounted on a windshield or dash board of a vehicle for creating a safe life zone or green zone around a driver seat; anda Bluetooth receiver, and wherein the Bluetooth transmitter sends a disable signal to the Bluetooth receiver to prevent texting operation or making calls, when the driver of the vehicle operates a mobile communication device for texting or messaging or initiating a call while driving a vehicle based on a sensor output;a master control module, and wherein the master control module is communicatively connected to a main control system of the vehicle;a plurality of slave modules, wherein the plurality of slave modules is positioned within vehicle around a diver seat and is communicatively coupled to the master control module;wherein the master control module is configured to establish a short range wireless communication network ...

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Номер записи: 92

20-01-2022 дата публикации

Eyewear system for detecting and indicating presence of coronavirus

Номер: US20220015700A1

Автор: Chefitz Allen B.

Принадлежит: 123IV, Inc.

An article of manufacture comprises an optical shade configured for removable attachment to eyewear, e.g., eyeglasses that are retrofitted to include a micro-fluidic tear collector in a nose pad. The optical shade comprises a lens having a lateral flow assay comprising an antibody having an associated fluorescent tag. The fluorescent tag is configured to fluoresce and change a color of the lens upon detection by the flow assay of an antigen that matches the antibody. The antigen comprises viral constituents, such as SARS-CoV-2. The color change of the lens is visible and indicates presence of Covid-19 infection. 1. An article of manufacture , comprising:an optical shade comprising a lens supporting a flow assay, the flow assay comprising an antibody having an associated fluorescent tag, the shade configured for removable attachment to eyewear, the fluorescent tag configured to fluoresce and change a color of the lens upon detection by the flow assay of an antigen that matches the antibody.2. The article of manufacture as described in wherein the optical shade comprises a nose pad that receives and channels the tear to the flow assay.3. The article of manufacture as described in wherein the antigen comprises viral constituents.4. The article of manufacture as described in wherein the viral constituents comprise SARS-CoV-2.5. The article of manufacture as described in wherein the flow assay is uniquely associated with the antigen.6. The article of manufacture as described in wherein the color change of the lens is visible and indicates presence of Covid-19 infection.7. The article of manufacture as described in wherein the flow assay is a lateral flow assay configured across a width of the lens.8. An eyewear system claim 1 , comprising:eyewear;an optical shade configured for removable attachment to the eyewear;the eyewear comprising a micro-fluidic collector integrated into a nose pad and configured to collect, non-invasively, a tear; andthe optical shade comprising a ...

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Номер записи: 93

12-01-2017 дата публикации

SYSTEM AND METHOD OF MONITORING RESPIRATORY PARAMETERS

Номер: US20170007159A1

Автор: Brown Mike A., Dieffenderfer James P., Johnson Leigh M., Muth John F.

Принадлежит: North Carolina State University

A spirometer includes a housing, a mouthpiece coupled to the housing, and a measurement unit. The measurement unit is configured to receive air expelled by a user, and generate an electrical quantity corresponding to a peak expiratory flow or a forced expiratory volume based on the expelled air. The spirometer also includes a processing module supported by the housing, and configured to receive the electrical quantity from the measurement unit, a display coupled to the measurement unit to display an indication of the peak expiratory flow or the forced expiratory volume, and an energy harvester. The energy harvester is coupled to the measurement unit and the processing module, and is configured to receive energy from one of a group consisting of the measurement unit and an energy sensor, store the received energy in an energy storage device, and transfer the energy to the processing module. 1. A spirometer comprising:a housing;a mouthpiece coupled to the housing;a measurement unit configured to receive air expelled by a user, and generate an electrical quantity corresponding to a peak expiratory flow or a forced expiratory volume based on the expelled air;a processing module supported by the housing, and configured to receive the electrical quantity from the measurement unit; and receive energy from one of a group consisting of the measurement unit and an energy device,', 'store the received energy in an energy storage device, and', 'transfer the energy to the processing module., 'an energy harvester coupled to the measurement unit and the processing module, the energy harvester configured to'}2. The spirometer of claim 1 , wherein the housing includes a set of guiderails along a length of the housing claim 1 , and wherein the mouthpiece is movable relative to the housing between a first position in which the mouthpiece is recessed within the housing claim 1 , and a second position in which the mouthpiece is exposed outside the housing.3. The spirometer of claim 2 , ...

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Номер записи: 94

12-01-2017 дата публикации

UNOBTRUSIVE OVULATION TRACKING SYSTEM AND METHOD USING A SUBJECTS HEART RATE

Номер: US20170007214A1

Автор: Dillen Paulus Henricus Antonius

Принадлежит:

The present invention relates to a system for unobtrusive fertility tracking, comprising a sensor for obtaining a heart signal, a processing unit configured to determine a subject's heart rate from the heart signal, and an evaluation unit configured to analyze the subject's heart rate to predict likelihood of ovulation. The processing unit is further configured to extract heart rate variability features from the heart signal, and the evaluation unit is further configured to predict likelihood of ovulation based on the heart rate variability features. 1. System for unobtrusive ovulation tracking , comprising:a sensor for obtaining a heart signal,a processing unit configured to process the heart signal, andan evaluation unit configured to analyze the heart signal to predict likelihood of ovulation,wherein the processing unit is configured to extract heart rate variability features from the heart signal, and wherein the evaluation unit is further configured to predict likelihood of ovulation based on the heart rate variability features.2. System according to claim 1 , wherein the evaluation unit comprises a phased locked loop which locks onto the heart rate variability features to predict likelihood of ovulation.3. System according to claim 1 , comprising an activity determination unit configured to provide an activity indicator indicative of a current activity level and/or a user's physical condition claim 1 , in particular a circadian rhythm or phase of the subject claim 1 , wherein the evaluation unit is further configured to predict the likelihood of ovulation based on said activity indicator.4. System according to claim 3 , further comprising a motion sensor configured to determine motion and/or orientation data of the subject claim 3 , wherein the activity determination unit is configured to provide the activity indicator based on said motion and/or orientation data.5. System according to claim 3 , comprising an ambient sensor configured to determine an ambient ...

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Номер записи: 95

12-01-2017 дата публикации

ENDOCYTE CANNULA

Номер: US20170007216A1

Автор: Cagnes Lucia

Принадлежит:

An endocyte cannula is designed to provide improved and more productive Pap smear tests. The endocyte cannula includes a proximal portion and a distal portion. The proximal portion may include a fitting to connect to a user-actuated tool, such as a syringe. The distal portion may include a corkscrew feature to facilitate movement of the cannula through dense tissue. The distal portion may further include a plurality of apertures to aspirate mucus and reduce the risk of trauma or perforation. 1. A medical device comprising:a hollow tubular body having a proximal end and a distal end, wherein the proximal end is configured to connect to a user-control mechanism.2. The medical device of claim 1 , wherein the distal end of the hollow tubular body further comprises a corkscrew-shaped portion comprising at least one spiral.3. The medical device of claim 2 , wherein the distal end further comprises at least one aperture claim 2 , the aperture having a first opening through an outer wall of the medical device and a second opening through the hollow tubular body.4. The medical device of claim 3 , wherein the at least one aperture is configured to aspirate bodily tissues.5. The medical device of claim 4 , wherein the proximal end further comprises a fitting configured to connect to the user-control mechanism.6. The medical device of claim 6 , wherein the fitting comprises a luer lock.7. The medical device of claim 6 , wherein the user-control mechanism is a syringe.8. The medical device of claim 7 , wherein the syringe interfaces with the hollow tubular body to create a force through the medical device.9. The medical device of claim 8 , wherein the hollow tubular body is configured to be received into a body cavity.10. The medical device of claim 9 , wherein the corkscrew-shaped portion is configured to collect cells from a body cavity.11. The medical device of claim 10 , wherein the body cavity is an endocervical canal.12. The medical device of claim 11 , wherein the hollow ...

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Номер записи: 96

12-01-2017 дата публикации

TISSUE SAMPLING DEVICES, SYSTEMS AND METHODS

Номер: US20170007217A1

Автор: GWERDER ERIC J., KEAST Thomas, ROSCHAK Edmund J., Schwardt Jeffrey, Weiss Aaron M.

Принадлежит: BRONCUS MEDICAL INC.

Methods, devices, and systems are described herein that allow for improved sampling of tissue from remote sites in the body. A tissue sampling device comprises a handle allowing single hand operation. In one variation the tissue sampling device includes a blood vessel scanning means and tissue coring means to excise a histology sample from a target site free of blood vessels. The sampling device also includes an adjustable stop to control the depth of needle penetration. The sampling device may be used through a working channel of a bronchoscope. 120-. (canceled)21. A tissue sampling system for obtaining a core of tissue from a sample area , the system comprising: an elongate sheath having a flexibility to advance through tortuous airway anatomy;', 'a shaft removably disposed with the sheath, where the shaft and sheath are moveable relative to one another, the shaft comprising a proximal section and a distal section, and a lumen extending there through;', 'a coring tip located at the distal section of the shaft, the coring tip having a tissue cutting distal end, and a cavity therein adapted to cut and capture a tissue sample shaped as a long core upon advancement of the coring tip through a target tissue, the cavity being in fluid communication with the lumen; and', 'a handle comprising a single-handed actuation assembly operative to advance the coring tip a pre-determined distance from the sheath at a velocity and force which penetrates the target tissue surface and captures the tissue sample in the shape of the long core; and, 'a tissue sampling device, the device comprisingat least one device advanceable from the sheath.22. The system of claim 21 , wherein the at least one device is selected from the group consisting of: a temperature measuring device claim 21 , an optical fiber claim 21 , an aspiration catheter claim 21 , cautery probes for cauterizing bleeders claim 21 , argon plasma probes for surface ablation claim 21 , cryotherapy catheters for ablation or ...

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Номер записи: 97

14-01-2016 дата публикации

BIOLOGICAL TISSUE BIOPSY DEVICE

Номер: US20160007975A1

Автор: Hwang Jeong Kye, Kim Ji Il, KIM Sung Min, Moon In Sung, Park Sun Cheol, Yang In Chul

Принадлежит:

The present invention relates to a biological tissue biopsy device including a body extending in a longitudinal direction, an outer needle installed to be connected to one side of the body and be extended in a longitudinal direction and including a first tube having a hollow portion formed therein and a second tube disposed in a direction parallel to the first tube to guide a hemostatic substance, an inner needle provided inside the first tube and extending in a longitudinal direction, and a sliding means provided in the body and installed to be connected to one end of the inner needle so as to enable the inner needle to move forward and backward. Here, the sliding means causes the inner needle to move a predetermined distance from the hollow portion of the first tube and be inserted into a target site. 1. A biological tissue biopsy device comprising:a body extending in a longitudinal direction;an outer needle installed to be connected to one side of the body and be extended in a longitudinal direction and comprising a first tube having a hollow portion formed therein and a second tube disposed in a direction parallel to the first tube to guide a hemostatic substance;an inner needle provided inside the first tube and extending in a longitudinal direction; anda sliding means provided in the body and installed to be connected to one end of the inner needle so as to enable the inner needle to move forward and backward,wherein the sliding means causes the inner needle to move a predetermined distance from the hollow portion of the first tube and be inserted into a target site.2. The biological tissue biopsy device according to claim 1 , wherein the body comprises an ultrasonic probe formed on one side thereof.3. The biological tissue biopsy device according to claim 1 , wherein the body comprises a safety means formed on the other side thereof to control the sliding means.4. The biological tissue biopsy device according to claim 1 , wherein the body comprises:a ...

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Номер записи: 98

11-01-2018 дата публикации

Endoscopic Ultrasound Fine Needle Aspiration Device

Номер: US20180008127A1

Автор: Brian Tinkham, Daneil BACON, Michal Weisman, Robert DeVries, Shawn Ryan

Принадлежит: Boston Scientific Scimed Inc

A handle for a medical device includes a proximal segment defining a proximal lumen extending therethrough and sized and shaped to receive an endoscopic medical device therein. A medial segment is received within a distal portion of the proximal segment and has an outer diameter smaller than an inner diameter thereof. A medial lumen extends through the proximal segment and is open to the proximal lumen. A distal segment is received within a distal portion of the medial segment and defines a distal lumen extending therethrough open to the medial lumen. The distal segment has an outer diameter smaller than an inner diameter of the medial segment. The medial segment includes a first movement limiting mechanism limiting movement of an endoscopic medical device inserted therethrough along an axis of the distal lumen and a second movement limiting mechanism limiting advancement of an endoscope attached to the distal body portion.

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Номер записи: 99

14-01-2021 дата публикации

System for collecting and utilizing health data

Номер: US20210007643A1

Автор: Mouad Lamrani, Sami Antero Lakka, Stephen D. Newman

Принадлежит: MENICON CO., LTD.

A system for collecting and utilizing health data can include collecting data relative to a patient's health and aggregating the data with other sources of data to define a database. The patient data can be collected using an electronic device, such as a smart contact lens or smart contact lens container. The data within the database can be manipulated, organized, or otherwise processed to determine trends, relationships, and other characteristics of the database. The characteristics of the database can be correlated to predict a health condition of the patient, generate a healthcare recommendation, or a combination thereof.

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Номер записи: 100