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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 2786. Отображено 100.
05-01-2012 дата публикации

Apparatus and methods for enzymatic debridement of skin lesions

Номер: US20120004627A1
Автор: Amihay Freeman, Eran Hirszowicz, Michal Be'eri-Lipperman
Принадлежит: EnzySurge Ltd, Ramot at Tel Aviv University Ltd

An apparatus for debridement of devitalized tissue in skin lesions, that includes a plurality of height- and angle-adjustable inlet tubes and at least one outlet tube and a member that forms an occlusive seal around a skin lesion. The plurality of inlet tubes is adapted for directing a continuous stream of enzymatic solution to the surface and into the entire volume of the wound bed of the lesion and the at least one outlet is adapted for removing the enzymatic solution, fluids draining from the lesion and tissue debris from the occluded skin lesion.

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Номер записи: 1
16-02-2012 дата публикации

Method and apparatus for increasing blood flow through an obstructed blood vessel

Номер: US20120041459A1
Автор: David Fiorella, Henry Woo
Принадлежит: CLEVELAND CLINIC FOUNDATION

A method of increasing blood flow through an obstructed blood vessel includes providing an expandable member substantially made of a mesh having a plurality of interstices. The expandable member is inserted into the blood vessel, positioned within the blood vessel with the proximal member end upstream of the distal member end and the member body located radially adjacent at least a portion of an obstruction, and expanded to bring at least a portion of the member body into contact with the obstruction. An outward radial force is exerted on the obstruction to dislodge at least one fragment from the obstruction and to enhance blood flow through the blood vessel past the obstruction. The at least one fragment is passed through at least one interstice of the member body in the radial direction, and is selectively retained within the expandable member.

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Номер записи: 2
23-02-2012 дата публикации

Methods and Devices for Conduit Occlusion

Номер: US20120042880A1
Автор: Daniel S. Currie, Kathy Lee-Sepsick, Max S. Azevedo
Принадлежит: FEMASYS INC

The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of elements for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable or degradable material that supports tissue ingrowth or wound healing or a similar response that replaces the cured occlusive material leaving little or no original occlusive material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.

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Номер записи: 3
08-03-2012 дата публикации

Method and apparatus for treatment of intracranial hemorrhages

Номер: US20120059285A1
Автор: Azita Soltani, Brenton Nistal, Curtis Genstler, Raymond M. Wolniewcz, III, Robert L. Wilcox, Ronald L. Haas
Принадлежит: Ekos LLC

An ultrasound catheter with a lumen for fluid delivery and fluid evacuation, and an ultrasound source is used for the treatment of intracerebral or intraventricular hemorrhages. After the catheter is inserted into a blood clot, a lytic drug can be delivered to the blood clot via the lumen while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the lumen.

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Номер записи: 4
08-03-2012 дата публикации

Device and method for removing material from a hollow anatomical structure

Номер: US20120059356A1
Автор: Giorgio di Palma, William A. Cartier, William Appling, William C. Hamilton, Jr.
Принадлежит: Individual

A medical device for removing a material from a hollow anatomical structure is provided. The device includes a radially expandable capture member. The device includes a treatment segment that is positioned distally of the capture member in use and having at least one exit port adapted for delivering a fluid agent to the material. The device includes an embolic capture device that is positioned distally of the treatment segment in use and including a radially expandable filter for capturing a part of the material which travels downstream of the treatment segment. Additionally, a method is provided herein for infusing, injecting, distributing, or releasing an intended fluid into a hollow anatomical structure.

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Номер записи: 5
19-04-2012 дата публикации

Ultrasound transducer and cooling thereof

Номер: US20120095371A1
Автор: Ariel Sverdlik, Or Shabtay
Принадлежит: Cardiosonic Ltd

An ultrasonic transducer device for producing ultrasonic beams comprises a body vibratable at ultrasonic frequencies and an extensive surface for beam emanation, the device configured to produce an unfocused, or alternatively a focused, power beam for tissue ablation, the power beam being produced by vibration over the body of the transducer and emanating from the extent of the surface, whereby the extensive surface becomes subject to convective cooling when immersed in a fluid by a chimney effect set up by said unfocused beam.

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Номер записи: 6
19-04-2012 дата публикации

Ultrasound catheter for providing a therapeutic effect to a vessel of a body

Номер: US20120095389A1
Автор: Frederick J. Bennett, Gary Lichttenegger, James E. Rodriguey, John Zhang, Katsuro Tachibana
Принадлежит: Ekos LLC

The invention relates to a catheter system. The system comprises a catheter body having a chamber containing a low acoustic impedance medium. The catheter body includes an elongated body with an external surface and an ultrasound transducer having an external side between a first end and a second end. The ultrasound transducer is positioned over the external surface of the elongated body such that the first end is adjacent to the chamber.

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Номер записи: 7
02-08-2012 дата публикации

Apparatus and methods for treating obstructions within body lumens

Номер: US20120197193A1
Автор: Gwendolyn Watanabe, Jeffrey A. Krolik, Juan Domingo, Lucas Fernandez, Ray Betelia
Принадлежит: Hotspur Technologies LLC

Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.

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Номер записи: 8
01-11-2012 дата публикации

Surgical instrument for injecting a drug into prostate tissue

Номер: US20120277721A1
Автор: Johann J. Neisz, Sidney F. Hauschild, Stephen L. Bolea
Принадлежит: Bolea Stephen L, Hauschild Sidney F, Neisz Johann J

A needleless injector including a body at a proximal end, a shaft extending distally from the body, at least one injection orifice at a distal end of the shaft in fluid communication with a fluid chamber at the proximal end, a pressure source in communication with the fluid chamber, and a tissue tensioner located at the distal end of the shaft proximal to the injection orifice, wherein the distal end including the tissue tensioner and injection orifice is positionable within a urethral lumen so that when the tissue tensioner is deployed, tissue of the urethra is tensioned at a location for injection of fluid from the injection orifice into the tissue of the urethra.

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Номер записи: 9
08-11-2012 дата публикации

Apparatus and methods for clot dissolution

Номер: US20120283699A1
Автор: Alexander Khairkhahan, Denise Demarais, Dino De Cicco, Kelvin Ning, Michael A. Evans, Tyler Jon Strang
Принадлежит: TYCO HEALTHCARE GROUP LP

Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.

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Номер записи: 10
07-02-2013 дата публикации

Methods and systems for treatment of acute ischemic stroke

Номер: US20130035628A1
Автор: Alan K. Schaer, Gregory M. Hyde, Michi E. Garrison, Tony M. Chou
Принадлежит: Silk Road Medical Inc

Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.

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Номер записи: 11
06-06-2013 дата публикации

Surgical instrument for injecting a drug into prostate tissue

Номер: US20130144265A1
Автор: Johann J. Neisz, Sidney F. Hauschild, Stephen L. Bolea
Принадлежит: AMS Research LLC

Method and surgical instrument for treating prostate tissue including a surgical instrument having a main body, a needle deployment port, a needle, first and second handles and a lockout release mechanism to limit needle extension. Additionally, a kit includes the surgical instrument, together with a cystoscope, and optionally a syringe and reservoir of ethanol. The method includes needle-less injection and visualizing the ethanol injection by delivering both an echogenic agent and ethanol either by needle or needle-less injection or by providing an ultrasonically visible marker near the tip of the ethanol delivery cannula. The method also includes extending the needle transversely of the instrument housing using a link assembly.

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Номер записи: 12
08-08-2013 дата публикации

Ultrasound transceiver and cooling thereof

Номер: US20130204167A1
Автор: Ariel Sverdlik, Or Shabtay
Принадлежит: Cardiosonic Ltd

An ultrasonic transceiver device for producing ultrasonic beams comprises a body vibratable at ultrasonic frequencies and an extensive surface for beam emanation, the device configured to produce an unfocused, or alternatively a focused, power beam for thermal tissue damage, the power beam being produced by vibration over the body of the transceiver and emanating from the extent of the surface, whereby the extensive surface becomes subject to convective cooling when immersed in a fluid by a chimney effect set up by said unfocused beam.

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Номер записи: 13
30-01-2014 дата публикации

Method and treatment for the reduction of atherosclerosis

Номер: US20140030363A1
Автор: Ajay J. Panchal
Принадлежит: Ajay J. Panchal

A method for treating atherosclerosis in a patient comprising maintaining an elevated level of alcohol in the patient's blood; and administering a calcium chelating agent is provided.

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Номер записи: 14
06-01-2022 дата публикации

BALLOON ENCAPSULATION AND ISOVOLUMETRIC SUCTION THROMBECTOMY CATHETER AND METHODS THEREOF

Номер: US20220000498A1
Автор: De Silva Gayan, Genin Guy, Lee Sanghun A., Leuthardt Eric, Osbun Joshua, Williams Dillon, Wirtz Alexander, Zayed Mohamed
Принадлежит:

The disclosure provides for an adjustable catheter system with isovolumetric suction and restoration of fluid for the removal of a thrombus and a method of use thereof. The catheter system includes an inner catheter and an outer sheath surrounding at least a portion of the inner catheter. The inner catheter may include at least three lumina extending from the proximal end to the distal end of the inner catheter, at least one infusion fenestration along the infusion segment, and a distal encapsulation balloon at the distal end. The outer sheath may include at least three lumina extending from the proximal end to the distal end of the outer sheath and a proximal encapsulation balloon at the distal end. The catheter system may further include an agitator for mechanical morcellation of the thrombus. 1. A catheter system for removal of a thrombus from a vessel , comprising: at least one infusion fenestration along the infusion segment; and', 'a distal encapsulation balloon at the distal end; and, 'an inner catheter having a proximal end, an infusion segment, and a distal end, the inner catheter comprising 'a proximal encapsulation balloon at the distal end,', 'an outer sheath having a proximal end and a distal end, the outer sheath comprisingwherein the outer sheath surrounds at least a portion of the inner catheter and the distal encapsulation balloon and the proximal encapsulation balloon are separated by a distance along the infusion segment.2. The catheter system of claim 1 , wherein the distal encapsulation balloon and the proximal encapsulation balloon are compliant balloons operable to accommodate varying vessel sizes and minimize damage or injury to the vessel.3. The catheter system of claim 1 , wherein the distance between the distal encapsulation balloon and the proximal encapsulation balloon is adjustable.4. The catheter system of claim 1 , wherein the distance between the distal encapsulation balloon and the proximal encapsulation balloon form a thrombolytic ...

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Номер записи: 15
07-01-2016 дата публикации

Shock Wave Applicator with Movable Electrode

Номер: US20160000645A1
Автор: Christopher M. Cashman, Iulian Cioanta
Принадлежит: Sanuwave Inc

A shock wave applicator includes a reflector and a movable shockwave-generating electrode disposed in the reflector at a first focal point. The reflector is at least a portion of an ellipsoidal shape having a long and small axis with the first focal point and a second focal point on the long axis, and the reflector terminates at an edge defining a membrane-covered aperture on a plane intersecting the small axis and coincident with the second focal point.

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Номер записи: 16
14-01-2016 дата публикации

METHODS AND APPARATUS FOR TREATING EMBOLISM

Номер: US20160008014A1
Автор: Cox Brian J., Lubock Paul, Rosenbluth Robert F.
Принадлежит:

A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material. 130-. (canceled)31. A method of treating a pulmonary embolism that at least partially restricts blood flow through a pulmonary vessel , the method comprising:delivering an embolectomy device at least partially through the pulmonary embolism, wherein the embolectomy device includes an expandable braided structure;deploying the braided structure within at least a portion of the pulmonary embolism, wherein deploying the braided structure includes withdrawing a delivery sheath such that the braided structure expands and forms a flow channel that restores blood flow through the pulmonary embolism and wherein, in a deployed state, the braided structure has a cylindrical portion positioned between a first portion and a second portion that individually extend radially outwardly from the cylindrical portion such that a surface area to length ratio of the individual first and second portions is greater than the surface area to length ratio of the cylindrical portion;moving the embolectomy device and at least a portion of the pulmonary embolism along the pulmonary vessel; andwithdrawing the embolectomy device and at least a portion of the pulmonary embolism from the pulmonary vessel.32. The method of wherein deploying the braided structure includes expanding at least one of the first and second portions distal to the pulmonary embolism.33. The method of wherein deploying the braided structure comprises expanding the braided structure such that a combined surface area of the cylindrical portion claim 31 , first portion claim 31 , and the second ...

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Номер записи: 17
12-01-2017 дата публикации

CATHETER WITH MULTIPLE ULTRASOUND RADIATING MEMBERS

Номер: US20170007815A1
Автор: ABRAHAMSON TIM, BARRERE WM. GERRIT, Cohen Amy, Genstler Curtis, KEILMAN GEORGE, OLIVER LEONARD R., PESKIN NATALYA, Wilcox Robert L., Wilson Richard R.
Принадлежит:

A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The ultrasonic catheter system comprises a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end, a fluid delivery lumen, at least one ultrasound radiating element positioned in the treatment zone, wiring electrically coupled to the at least one ultrasound radiating element and extending through the tubular body and terminating at a connector, and a control system comprising external circuitry and an isolation pod that is configured to be electrically connected to the connector, the isolation pod being positioned between the tubular body and the external system and comprising an isolation barrier and circuitry for driving the ultrasound radiating element. 18-. (canceled)9. An ultrasonic catheter comprising:a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end;a plurality of fluid delivery lumens defined within the tubular body;an inner core comprising at least one ultrasound radiating element;a plurality of cooling fluid channels defined between at least an inner surface of the tubular body and an outer surface of the inner core, each cooling fluid channel being positioned generally radially between two fluid delivery lumens.10. The ultrasonic catheter of claim 9 , wherein the catheter includes three fluid delivery lumens.11. The ultrasonic catheter of claim 9 , wherein the catheter includes three cooling fluid channels.12. The ultrasonic catheter of claim 9 , wherein the three fluid delivery lumens spaced approximately 120 degrees radially apart from each other.13. The ultrasonic catheter of further including a control system comprising external circuitry and an isolation pod that is configured to be electrically connected to the inner core claim 9 , the isolation claim 9 , pod being positioned ...

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Номер записи: 18
14-01-2021 дата публикации

UROLITHIASIS REMOVING DEVICE AND METHOD

Номер: US20210007758A1
Автор: CHEON Byung Sik, CHUNG Deok Gyoon, KWON Dong Soo
Принадлежит:

A urolithiasis removing device according to one embodiment can comprise: an insertion tube; a guide which is inserted into the insertion tube and which is relatively movable with respect to the insertion tube; a wire which is inserted into the guide and which is relatively movable with respect to the guide; a basket positioned in front of the wire and capable of holding urolithiasis; and a control unit for determining the size of the urolithiasis on the basis of the relative movement of the guide with respect to the insertion tube or the relative movement of the wire with respect to the guide. 1. A urolithiasis removing device comprising:an insertion tube;a guide configured to be inserted into an inner side of the insertion tube and relatively movable with respect to the insertion tube;a wire configured to be inserted into an inner side of the guide and relatively movable with respect to the guide;a basket disposed in front of the wire and configured to hold a stone; anda controller configured to determine a size of the stone based on a relative movement of the guide with respect to the insertion tube or a relative movement of the wire with respect to the guide.2. The urolithiasis removing device of claim 1 , wherein the controller is configured to determine the size of the stone based on a relative position of the wire with respect to the guide in a state in which the basket holding the stone is caught on a front end of the guide.3. The urolithiasis removing device of claim 2 , further comprising: 'wherein the controller is configured to determine the relative position of the wire with respect to the guide based on a distance detected by the distance measurer.', 'a distance measurer disposed in the wire and configured to measure a relative movement distance of the wire with respect to the guide,'}4. The urolithiasis removing device of claim 3 , wherein the distance measurer is provided at a rear end of the wire and configured to measure a distance from the rear end ...

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Номер записи: 19
10-01-2019 дата публикации

METHODS AND SYSTEMS FOR TREATMENT OF ACUTE ISCHEMIC STROKE

Номер: US20190008534A1
Автор: Chou Tony M., Garrison Michi E.
Принадлежит:

Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described. 135.-. (canceled)36. A system of devices for performing a medical procedure at a treatment site in a cerebral vessel of a patient , the system comprising:a catheter having a catheter lumen having an inner diameter and a distal end; andan inner member sized to slide within the catheter lumen, wherein the inner member defines a single lumen and has a distal portion and a distal-most end having a distal opening, the distal portion having a first outer diameter that tapers distally to a second outer diameter that is smaller than the first outer diameter,wherein the system is in an advancement configuration when the inner member is positioned coaxially in the catheter lumen with the distal portion positioned distal to the distal end of the catheter,wherein a flexibility of the distal portion decreases smoothly from a flexibility at the second outer diameter to a flexibility at the first outer diameter when the system is in the advancement configuration, andwherein the system of devices is sufficiently flexible that, when the system is in the advancement configuration, the system is configured to be advanced distal to a petrous portion of an internal carotid artery.37. The system of claim 36 , wherein a stent retriever is positioned within the single ...

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Номер записи: 20
18-01-2018 дата публикации

Treatment Techniques Using Radiation, Electromagnetic Fields and Small-Scale Injectable Machines

Номер: US20180014798A1
Автор: Christopher V. Beckman
Принадлежит: Individual

The present invention includes new techniques for radiotherapy and other external electromagnetic influence of treatment subjects. In one aspect of the invention, a plurality of nano-scale or other small-scale machines is introduced to the blood stream (for example, by hypodermic injection). The design of each small-scale machine may include different sub-devices and electrostatic or magnetic charges, at different surface or internal locations. An electromagnetic and/or electrostatic control system the remotely alters the orientation and location of the small-scale machines, and applies the machines, and variably applies different sub-devices to different treatment targets. In some aspects, the sub-devices include actuable protection and sub-devices, to deliver drugs or other factors at specific locations commanded by the control system or a user.

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Номер записи: 21
21-01-2016 дата публикации

Dynamic Microvalve Protection Device

Номер: US20160015508A1
Автор: Aravind Arepally, Brett E. Naglreiter, Bryan M. Pinchuk, James E. Chomas, John Martin, Leonard Pinchuk
Принадлежит: Surefire Medical Inc

An apparatus includes a delivery catheter having a deployable dynamic valve that dynamically opens and closes in response to relative fluid pressure thereabout, particularly while in an anatomical lumen. The valve is maintained in a collapsed configuration during introduction to a treatment site. The valve is adapted to automatically move from the collapsed configuration to a deployed configuration at the treatment site.

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Номер записи: 22
17-01-2019 дата публикации

AXIAL LENGTHENING THROMBUS CAPTURE SYSTEM

Номер: US20190015122A1
Автор: Ngo Tung Hoang, Nguyen Duy, Nguyen Thanh Van
Принадлежит:

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions. 119-. (canceled)20. A clot capture system , comprising:a tubular body comprising a first end and a second end, the first end having an opening,wherein the tubular body is transformable to a first expanded configuration in which the first end is expanded, wherein the second end is compressed in the first expanded configuration, wherein the tubular body is folded between the first end and the second end such that a compressed portion of the tubular body is within an expanded portion of the tubular body, wherein the tubular body has a first expanded axial length in the first expanded configuration,wherein the tubular body is transformable to a second expanded configuration in which the tubular body has a second expanded axial length greater than the first expanded axial length.21. The clot capture system of claim 20 , further comprising an expanding guide catheter.22. The clot capture system of claim 20 , further comprising a funnel tip catheter.23. The clot capture system of claim 20 , wherein the tubular body is configured to be retracted through a funnel opening of an expanding guide catheter.24. The clot capture system of claim 20 , wherein the tubular body is configured to at least partially surround a thrombus in the second expanded configuration.25. The clot capture system of claim 20 , wherein the tubular body and a thrombus are configured to retracted into an expanding guide catheter.26. The clot capture system of claim 20 , further comprising at least one anchor.27. A clot capture system claim 20 , comprising:a tubular body comprising a first end and a second end, the first end having an opening,wherein the tubular body is transformable to a first expanded configuration in which the ...

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Номер записи: 23
21-01-2021 дата публикации

Autonomous endoscopic system and control method therefor

Номер: US20210015353A1
Автор: Byung Sik CHEON, Deok Gyoon CHUNG, Dong Soo Kwon
Принадлежит: Easyendo Surgical Inc, Korea Advanced Institute of Science and Technology KAIST

According to an embodiment, an autonomous endoscopic system capable of controlling movement of an endoscope inserted into a protective sheath installed in the body of a patient may comprise: an endoscope operating device capable of operating a relative position of the endoscope with respect to the protective sheath, a rolling angle of the endoscope, and a bending angle of a bending portion which is located at the end of the endoscope and is bendable; and a control unit for controlling the endoscope operating device, wherein the control unit controls the endoscope operating device on the basis of a driving record of the endoscope.

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Номер записи: 24
15-01-2015 дата публикации

Retrieval systems and methods for use thereof

Номер: US20150018929A1
Автор: Brian B. Martin, Martin S. Dieck
Принадлежит: Lazarus Effect Inc

The devices and methods described herein relate to improved structures for removing obstructions from body lumens. Such devices have applicability in through-out the body, including clearing of blockages within the vasculature, by addressing the frictional resistance on the obstruction prior to attempting to translate and/or mobilize the obstruction within the body lumen.

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Номер записи: 25
28-01-2016 дата публикации

OCCLUSION AND CLOT TREATMENT WITH INTRACORPOREAL PRESSURE SHOCK WAVES

Номер: US20160022294A1
Автор: CASHMAN Christopher M., CIOANTA Iulian
Принадлежит:

An intracorporeal pressure shock wave device to provide treatment within blood vessels artificial vessels and grafts that includes a frontal pressure shock wave reflector positioned at the distal end of an intracorporeal catheter to direct shock waves toward a treatment target, such as an occlusion and clot. 1. An intracorporeal pressure shock wave device to treat occlusions and blood clots comprising:a catheter sized to fit within at least one of a blood vessel, graft and artificial blood vessel, said catheter including radio-opaque markers;an inner member within the catheter; anda pressure shock wave reflector operatively attached to a distal end of the inner member to direct pressure shock waves, wherein the pressure shock wave reflector has a frontal exposure that angularly moves around a living hinge;a shock wave generator that is configured to produce pressure shock waves adjacent the reflector so that a focal volume of the pressure shock waves intersects at least one of a targeted occlusion and blood clots; anda membrane that creates an enclosed space around the shock wave generator and reflector that is filled with at least one of degassed water, saline solution and a saline-contrast mixture.2. The intracorporeal pressure shock wave device of claim 1 , wherein the reflector includes at least one of nitinol claim 1 , temperature memory metal claim 1 , hard plastic claim 1 , ceramic and glass.3. The intracorporeal pressure shock wave device of claim 1 , wherein the reflector includes a shape selected from the group consisting of elliptical claim 1 , paraboloid claim 1 , spherical claim 1 , planar claim 1 , and a combination of at least two of the foregoing.4. The intracorporeal pressure shock wave device of claim 1 , further comprising one or more distal passive protection devices and active suction devices to capture generated debris.5. An intracorporeal pressure shock wave device to treat occlusions and blood clots comprising:a catheter sized to fit within ...

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Номер записи: 26
28-01-2016 дата публикации

METHOD AND APPARATUS FOR LITHIASIS TREATMENT

Номер: US20160022297A1
Автор: Qian Kun, QIAN Xuliang
Принадлежит:

A medical apparatus may include an inflatable tubular component that can be inflated into a U-shaped structure, a plurality of connecting portions formed on a main body. In one embodiment, the connecting portion can be used for inflating an inflatable cylindrical component formed in the U-shaped structure. The medical apparatus treatment may further include a plurality of control filaments disposed on an inner surface of the U-shaped structure to control the size thereof, so the inner surface of the U-shaped structure can tightly press against an outer surface of the inflatable cylindrical component when it is inflated, and a chamber is formed in the U-shaped structure next to the inflated cylindrical component. When in use, the stones can be trapped into the chamber and chemical reagents can be introduced to either dissolve or disrupt the stones. 1. A medical apparatus comprising an inflatable tubular component that is configured to be inflated into a U-shaped structure , a plurality of connecting portions formed on a main body , wherein one of the connecting portions is used to inflate the inflatable tubular component , while the other connecting portion inflates an inflatable cylindrical component formed inside the U-shaped structure until an inner surface of the U-shaped structure tightly presses against an outer surface of the inflatable cylindrical component , and a chamber to trap bladder stones is formed in the U-shaped structure next to the inflated cylindrical component.2. The medical apparatus of claim 1 , further comprising a plurality of control filaments disposed on an inner surface of the U-shaped structure to control the size thereof.3. The medical apparatus of claim 1 , wherein the inflatable cylindrical component is detachable from the U-shaped structure.4. The medical apparatus of claim 2 , wherein the inflatable cylindrical component is detachable from the U-shaped structure.5. The medical apparatus of claim 1 , wherein the medical apparatus is ...

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Номер записи: 27
25-01-2018 дата публикации

Suction Lithotripsy Apparatus, Method and Kit

Номер: US20180021091A1
Автор: Cherry Thomas, Hardert Nicholas, Schaeffer Darin
Принадлежит:

Medical devices, methods and kits useful in the disruption and removal of unwanted materials, such as calculi and other formations, from within body lumens are described. The disclosure describes particular embodiments and methods useful in the lithotriptic removal of stones from the salivary glands. 1. A medical device , comprisinga pass-through fitting defining a main body and a side arm, the main body having a proximal end, a distal end, and a first inner wall defining a first lumen extending along a first axis, the side arm having a second inner wall defining a second lumen in fluid communication with the first lumen and extending along a second axis disposed at an angle to the first axis, the first lumen having a proximal opening disposed at the proximal end of the main body and a distal opening disposed at the distal end of the main body;a first sheath connected to the main body and in fluid communication with the first lumen;a second sheath connected to the side arm and in fluid communication with the second lumen; anda cannula having a proximal end and a distal end disposed through the first lumen proximal opening without blocking fluid flow into the first lumen proximal opening from the external environment such that the distal end of the cannula is disposed distal to the second lumen and a first fluid path is formed between the first inner wall and the cannula;wherein a wash fluid passed through the proximal end of the cannula exits the distal end of the cannula; andwherein a suction force applied to the second lumen pulls the wash fluid exiting the distal end of the cannula into the second lumen or pulls fluid from the external environment through the proximal opening of the first lumen and into the second lumen.2. The medical device of claim 1 , further comprising a valve attached to the second sheath and adapted to selectively permit and prevent the passage of fluid through the second lumen.3. The medical device of claim 1 , further comprising a ...

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Номер записи: 28
24-01-2019 дата публикации

Infusion Catheter and Method of Use

Номер: US20190021751A1
Автор: Bashir Riyaz, Green Nicholas A.
Принадлежит:

An infusion catheter has an elongate flexible shaft including a wall and a lumen extending between a proximal end and a distal end. The catheter also has a sealing member within the shaft lumen including a wall and a lumen. The catheter also has a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens connected to an end cap. The catheter also has a plurality of eluting arms extending radially around the central axis member, including lumens fluidly connected to the shaft lumen and the distal end cap. A method for treating a thrombus is also disclosed. 1. An infusion catheter comprising:an elongate flexible shaft comprising a wall and a lumen extending a length between a proximal end and a distal end;a sealing member within the shaft lumen comprising a wall and a lumen extending a length between a proximal end and a distal end, the distal end of the sealing member being attached to the distal end of the shaft;a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens; andan eluting member having a lumen fluidly connected to the distal end of the shaft lumen.2. The infusion catheter of further comprising:a plurality of eluting members, each eluting member having a lumen fluidly connected to the distal end of the shaft lumen.3. The infusion catheter of claim 2 , wherein the plurality of eluting members extend radially around the central axis member.4. The infusion catheter of claim 1 , wherein the eluting member and the elongate central axis member connect to a distal end cap.5. The infusion catheter of claim 1 , further comprising a frame having at least one tine within the lumen of the eluting member.6. The infusion catheter of claim 5 , wherein the frame is constructed from a shape memory material.7. The infusion catheter of claim 6 , wherein the shape memory material is nitinol.8. The infusion catheter of claim 6 , wherein the shape memory material forms a pear shape. ...

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Номер записи: 29
17-04-2014 дата публикации

Delivery and administration of compositions using interventional catheters

Номер: US20140107481A1
Автор: Edward I. Wulfman
Принадлежит: Medrad Inc

Systems and methods for delivery of therapeutic and/or diagnostic compositions to an interventional site having diseased or newly treated tissue are provided. Integrated interventional catheter systems incorporating surfaces coated with a diagnostic or therapeutic composition, or ports for infusing a diagnostic or therapeutic composition prior to, during or following an interventional procedure are provided.

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Номер записи: 30
22-01-2015 дата публикации

METHODS AND APPARATUSES FOR TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION

Номер: US20150025545A1
Автор: Gausmann Keith, Grenon Stephen M., Hutchinson Jordan W., Jans John Martin
Принадлежит:

A method of treating meibomian gland dysfunction is disclosed that comprises applying heat to an outer surface of a patient's eyelid to a temperature level to melt, loosen, or soften an obstruction located within a meibomian gland. The method also comprises maintaining the heat to the outer surface of the patient's eyelid for a period of time. The method further comprises applying a pressure to the outer surface of the patient's eyelid to express the obstruction from the meibomian gland. The obstruction may be located within a meibomian gland channel of the meibomian gland and the method may comprise expressing the obstruction located within a meibomian gland channel through a meibomian gland orifice. Applying the pressure may be done by positioning a pressure applicator into contact with the outer surface of the patient's eyelid and applying a pressure with the pressure applicator over a substantial portion of the patient's eyelid. 1. A method of treating meibomian gland dysfunction , comprising:applying heat to an outer surface of a patient's eyelid to a temperature level to melt, loosen, or soften an obstruction located within a meibomian gland;maintaining the heat to the outer surface of the patient's eyelid for a period of time; andapplying a pressure to the outer surface of the patient's eyelid to express the obstruction from the meibomian gland.2. The method of claim 1 , wherein the obstruction is located within a meibomian gland channel of the meibomian gland claim 1 , the method further comprising expressing the obstruction located within a meibomian gland channel from the meibomian gland channel through a meibomian gland orifice of the meibomian gland.3. The method of claim 1 , wherein the expressing is performed during the maintaining the heat for the period of time.4. The method of claim 1 , further comprising removing the heat from the outer surface of the patient's eyelid claim 1 , wherein the expressing is performed after the removing the heat from ...

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Номер записи: 31
28-01-2021 дата публикации

SUCTION EVACUATION DEVICE

Номер: US20210022759A1
Автор: Wan Shaw P.
Принадлежит:

A method for removing a stone from a patient comprising the steps of: providing a suction evacuation assembly which includes a sheath and one or more side arms; inserting and positioning a distal end of the sheath into a lumen or cavity of a patient's body containing a stones; connecting a tube to one of the side arms and to a collection bottle; connecting another tube to the collection bottle and a negative pressure system; visualizing the stone or foreign body using a scope inserted through the assembly; activating the negative pressure system in order to remove the stone from the cavity if the diameter of the stone is narrower than an inside diameter of the sheath and the side arm, or performing a lithotripsy on the stone to create fragments with a decreased diameter which allow the passage through the assembly; and collecting the stone in the collection bottle. 1. A device for removing a stone , a stone fragment or a foreign body from a patient comprising:a suction evacuation assembly which includes a sheath and a side arm;said side arm emanating from the outer surface of said sheath;an obturator having two or more channels which is configured to be inserted into a proximal end of the sheath and which extends beyond the distal end of said sheath and is releasably secured to the sheath; 'said sheath having a lumen contiguous with a lumen of said side arm; and', 'a pressure regulating mechanism accessible from the outer surface of said side arm and extending through said side arm, configured to allow an operator using the device to increase the negative pressure within the device by covering the pressure regulating mechanism or decrease the negative pressure within the device by uncovering the pressure regulating mechanism;'}a flexible cap is releasably secured to the proximal end of the sheath.2. The device of further comprising a guide wire which is configured to be introduced into a lumen or cavity of a patient containing one or more stones or foreign bodies ...

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Номер записи: 32
04-02-2016 дата публикации

Method and apparatus for treatment of intracranial hemorrhages

Номер: US20160030725A1
Автор: Curtis Gentsler, Douglas R. Hansmann, Jocelyn Kersten, Raymond M. Wolniewicz, Iii
Принадлежит: Ekos LLC

An ultrasound catheter with a lumen for fluid delivery and/or fluid evacuation, and ultrasound radiating elements is used for the delivery of therapeutic compounds to a target location. After the catheter is inserted into a cavity, a therapeutic compound can be delivered to the target location via selective activation of the ultrasound radiating elements. Selective activation of the ultrasound radiating elements can be used to cause fluid flow in a direction proximal and/or distal the catheter. Moreover, selective activating can be used to maintain fluid between certain of the ultrasound radiating elements.

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Номер записи: 33
30-01-2020 дата публикации

AXIAL LENGTHENING THROMBUS CAPTURE SYSTEM

Номер: US20200029985A1
Автор: Ngo Tung Hoang, Nguyen Duy, Nguyen Thanh Van
Принадлежит:

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions. 1. A clot capture system , comprising:an outer sheath comprising a central lumen;a dual lumen shaft configured to be positioned within the central lumen of the outer sheath;an inner pusher configured to be positioned within a first lumen of the dual lumen shaft;an anchor pusher configured to be positioned within a second lumen of the dual lumen shaft,an anchor coupled to the anchor pusher,a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening and a capture guide attached to a portion of the opening,wherein the shape memory tubular body and the anchor are compressed in a first configuration,wherein the shape memory tubular body is transformable to a second configuration in which the first end and the capture guide are radially expanded but the second end and a majority of the shape memory tubular body remains radially compressed within the lumen of the dual lumen shaft and the shape memory tubular body has a first expanded axial length with a first cross-section, wherein the first cross-section is substantially similar to the cross-section of the capture guide,wherein the shape memory tubular body is transformable to a third configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein the shape memory tubular body encapsulates the anchor in the third configuration.2. The clot capture system of claim 1 , further comprising two anchors.3. The clot capture system of claim 2 , wherein the two anchors have a central longitudinal axis that is coaxial.4. The clot capture system of claim 1 , further comprising three anchors.5. The clot capture ...

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Номер записи: 34
11-02-2016 дата публикации

RECANALIZING OCCLUDED VESSELS USING CONTROLLED ANTEGRADE AND RETROGRADE TRACKING

Номер: US20160038164A1
Автор: Katoh Osamu, Ogata Wayne
Принадлежит:

A method and systems for treating chronic total occlusions, particularly those that are difficult to treat, is disclosed. In this approach, recanalizing the CTO is achieved using a combined antegrade and retrograde approach. The proximal end of the occlusion is penetrated using an antegrade wire, using a traditional approach. Using collateral vessels, the distal end of the occlusion is crossed in a retrograde fashion and by appropriately maneuvering each member, a continuous channel is created. Additional elements such as capture devices, dilators and injection catheters are also disclosed. 1. A capture device for capturing an object , comprising:a tubular member with proximal and distal ends, the tubular member comprising an expandable member on its distal end;wherein the expandable member is configured to capture the object advancing in a retrograde or antegrade direction, wherein the object is a guidewire or thrombus.2. The capture device of claim 1 , wherein the expandable member comprises a plurality of ribs configured to flare out when the proximal end of the capture device is pushed towards the distal end claim 1 , or when the distal end of the capture device is pulled towards the proximal end.3. The capture device of claim 1 , wherein the expandable member comprises a plurality of twistable wires configured to expand when twisted in one direction and collapse when twisted in the opposite direction.4. The capture device of claim 1 , wherein the expandable member is rotatable.5. The capture device of claim 1 , further comprising means to extract the object via suction. This application is a divisional of prior U.S. patent application Ser. No. 12/150,111 filed Apr. 23, 2008, which is a continuation in part of U.S. patent application Ser. No. 11/706,041 filed Feb. 12, 2007, and claims the benefit of U.S. Provisional Patent Application Ser. No. 60/817,603 filed Jun. 28, 2006, and U.S. Provisional Patent Application Ser. No. 60/773,357 filed Feb. 13, 2006, which ...

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Номер записи: 35
05-02-2015 дата публикации

Methods and devices for endovascular embolization

Номер: US20150039019A1
Автор: Alejandro Espinosa, Andrew H. Cragg, Brett E. Naglreiter, John Logan, Nicholas A. Green, Scott R. Arp, Victor M. Gamez
Принадлежит: EMBA Medical Ltd

The present disclosure describes an occlusion device and methods of delivering the occlusion device. The occlusion device can include an expandable structure configured to move between an unexpanded configuration and an expanded configuration. The expandable structure can be configured to have an expansion ratio of at least about 5:1. Further, the occlusion device can be configured to prevent substantially all fluid from flowing past the occlusion device when the occlusion device is in the expanded configuration in the vessel.

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Номер записи: 36
24-02-2022 дата публикации

BALLOON CATHETER SYSTEM ASSISTED BY ULTRASOUND AND MICROBUBBLES AND METHOD FOR VASODILATION

Номер: US20220054155A1
Автор: HSIEH Zong-Han, LAI Chun-Yen, LEE Jen-Kuang, Tsai Chieh-Yu, YEH Chih-Kuang
Принадлежит:

A balloon catheter system assisted by ultrasound and microbubbles and a method for vasodilation are provided. The system includes: a controller; a sensor catheter; a highly focused ultrasound probe, and the highly focused ultrasound probe and the sensor catheter is connected to the controller; and a balloon catheter. The method of vasodilation includes: providing a sensor catheter into a blood vessel, and controlling a highly focused ultrasound probe to focus at a hardened portion of the blood vessel; removing the sensor catheter from the blood vessel and inserting a balloon catheter into the blood vessel; infusing microbubbles into the balloon catheter and controlling the highly focused ultrasound probe to start working to destroy a calcification point of the hardened portion of the blood vessel, and smoothly inflating the balloon catheter at the hardened portion of the blood vessel. 1. A balloon catheter system assisted by ultrasound and microbubbles , comprising:a controller;a sensor catheter;a highly focused ultrasound probe; anda balloon catheter,wherein the highly focused ultrasound probe and the sensor catheter are connected to the controller.2. A method for vasodilation , comprising:providing a sensor catheter into a blood vessel, and controlling a highly focused ultrasound probe to focus at a hardened portion of the blood vessel;removing the sensor catheter from the blood vessel and inserting a balloon catheter into the blood vessel;infusing microbubbles into the balloon catheter and controlling the highly focused ultrasound probe to start working to destroy a calcification point of the hardened portion of the blood vessel; andsmoothly inflating the balloon catheter at the hardened portion of the blood vessel.3. The method for vasodilation of claim 2 , wherein the microbubbles are infused into blood vessels claim 2 , and the microbubbles can be attached to target sites claim 2 , followed by activation of ultrasound and generating shock waves to destroy the ...

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Номер записи: 37
07-02-2019 дата публикации

SYSTEM AND METHOD FOR TREATMENT OF EUSTACHIAN TUBE FROM MIDDLE EAR APPROACH

Номер: US20190038470A1
Автор: Chan Randy S., Dean Marc, Ha Hung V., Lam Sivette, Muni Ketan P., Nguyen Andy, Poe Dennis S., Sudhoff Holger
Принадлежит:

A dilation catheter includes a shaft and an expandable element. The shaft includes a proximal portion and a distal portion. The distal portion includes a tip and a bend. The tip is sized and configured to pass through an isthmus of a Eustachian tube (ET). The bend is proximal to the tip. The bend is formed at an angle configured to provide insertion of the tip into the isthmus of the ET via an ear canal associated with the ET. The expandable element is disposed at the distal portion of the shaft. The expandable element is configured to transition between a non-expanded state and an expanded state. The expandable element in the non-expanded state is configured for insertion into the ET via the isthmus. The expandable element in the expanded state is configured to dilate the ET. 120.-. (canceled)21. A dilation catheter , comprising: (i) a gripping portion comprising an inflation port, and', '(ii) an elongate portion extending distally from the gripping portion along a longitudinal axis, wherein the elongate portion comprises a first cross-sectional dimension, wherein the elongate portion defines a first section of an inflation lumen, wherein the first section of the inflation lumen is in fluid communication with the inflation port of the gripping portion;, '(a) a rigid proximal shaft, wherein the rigid proximal shaft comprises'}(b) a flexible distal shaft extending distally from the elongate portion of the proximal shaft, wherein the flexible distal shaft is configured to flex relative to the longitudinal axis, wherein the flexible distal shaft defines a second section of the inflation lumen in fluid communication with the first section of the inflation lumen, wherein the flexible distal shaft comprises a tapered outer surface defining an opening in fluid communication with the second section of the inflation lumen; and(c) an inflatable balloon attached to the outer surface of the flexible distal shaft, wherein an interior of the inflatable balloon is in fluid ...

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Номер записи: 38
07-02-2019 дата публикации

DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS

Номер: US20190038748A1
Автор: Creighton Francis M.
Принадлежит:

A system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator is provided. In one embodiment, the invention relates to the control of magnetic particles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Examples of vascular occlusions targeted by the system include, but are not limited to, atherosclerotic plaques, including fibrous caps, fatty buildup, coronary occlusions, arterial stenosis, restenosis, vein thrombi, arterial thrombi, cerebral thrombi, embolisms, hemorrhages, other blood clots, and very small vessels. 1. (canceled)2. A method of treating a total occlusion in a vessel of a subject through external magnetomotive manipulation of magnetic particles , the method comprising:introducing a plurality of magnetic particles within vasculature of the subject,orienting a permanent magnet external to the blood vessel to establish a magnetic rotation plane of the permanent magnet, wherein the permanent magnet has a magnetic field and a directed magnetic gradient;programming a controller to cause the permanent magnet to rotate in a manner sufficient to cause the magnetic particles to agglomerate to form a plurality of magnetic rods within the vasculature to travel toward the total occlusion in the vessel in an end over end walking motion,wherein the end over end walking motion of each of the magnetic rods generates a stirring motion within the vasculature proximal to the total occlusion, andwherein the stirring motion facilitates contact of at least one of (i) an agent configured to facilitate visualization with an imaging modality or (ii) a drug ...

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Номер записи: 39
18-02-2021 дата публикации

DEVICES AND METHODS FOR TREATING BLOCKED BLOOD VESSELS

Номер: US20210045761A1
Автор: Bardsley Earl, Choe Jerome
Принадлежит: SHANGHAI WALLABY MEDICAL TECHNOLOGIES CO., INC.

The present teachings provide devices and methods of engaging, capturing, and retrieving emboli. Specifically, one aspect of the present teachings provides a device comprising a generally cylindrical body, with its proximal ends joining to a delivery system and a plurality of cells forming its luminal surface. The cylindrical body is configured to axially rotate as it radially expands. Another aspect of the present teachings provides a device comprising two elongated bodies one disposed within the other. As the device expands radially, both elongated bodies are configured to axially rotate independently. 1. An embolic capture device comprising:an elongated stent body having a distal end, a proximal end, an axial lumen extending from the distal end to the proximal end, and a luminal surface;at least two connecting struts attaching the elongated stent body to a pusher shaft;wherein the luminal surface of the elongated stent body has a plurality of cells; and each cell has a distal end, a proximal end, and a cell axis extending through both distal and proximal ends;wherein a first circumferential row of cells along the luminal surface of the elongated stent body have a first cell axis forming a first angle with a longitudinal axis of the stent body, and a second circumferential row of cells adjacent to the first circumferential row of cells having a second cell axis forming a second angle with the longitudinal axis of the elongated stent body; and the first and the second angles are different;andwherein the embolic capture device has a radially collapsed profile during delivery and a radially expanded profile upon deployment.2. The embolic capture device of claim 1 , wherein each cell is formed by two struts claim 1 , and at least one cell has different struts profile from at least one other cell.3. The embolic capture device of claim 1 , wherein at least one cell is formed by two wavy profiled struts claim 1 , configured to be symmetrical across a center of the cell ...

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Номер записи: 40
14-02-2019 дата публикации

METHODS AND SYSTEMS FOR TREATMENT OF ACUTE ISCHEMIC STROKE

Номер: US20190046218A1
Автор: Chou Tony M., Garrison Michi E.
Принадлежит:

Described are methods for performing a medical procedure at a treatment site in a cerebral vessel of a patient. The methods include positioning a system of devices into an advancement configuration, the system including a catheter and an inner member sized and shaped to slide within the catheter lumen. The inner member defines a single lumen and has a distal portion, the distal portion having a first outer diameter that tapers distally to a second outer diameter that is smaller than the first outer diameter. When positioned in the advancement configuration, the inner member extends coaxially through the catheter lumen and the distal portion of the inner member is positioned distal to the distal end of the catheter. The method further includes advancing the system of devices distal to a petrous portion of an internal carotid artery while the system of devices is positioned in the advancement configuration. 135.-. (canceled)36. A method of performing a medical procedure at a treatment site in a cerebral vessel of a patient , the method comprising: a catheter having a catheter lumen, an inner diameter and a distal end; and', 'an inner member sized and shaped to slide within the catheter lumen, wherein the inner member defines a single lumen and has a distal portion, the distal portion having a first outer diameter that tapers distally to a second outer diameter that is smaller than the first outer diameter,, 'positioning a system of devices into an advancement configuration, the system of devices comprisingwherein, when positioned in the advancement configuration, the inner member extends coaxially through the catheter lumen and the distal portion of the inner member is positioned distal to the distal end of the catheter; andadvancing the system of devices distal to a petrous portion of an internal carotid artery while the system of devices is positioned in the advancement configuration.37. The method of claim 36 , further comprising removing the inner member from the ...

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Номер записи: 41
13-02-2020 дата публикации

Thrombectomy systems and devices and methods of using the same

Номер: US20200046396A1
Автор: Ghassan S. Kassab, Seshadri Raju
Принадлежит: CVDevices LLC

Thrombectomy systems and devices and methods of using the same. In an exemplary embodiment of a thrombectomy system of the present disclosure, the thrombectomy system comprises a thrombectomy sheath, comprising a circumferential outer wall reinforced with a reinforcement, configured as an elongated tube having a lumen therethrough; and a sonovisible element positioned at or near a distal end of the circumferential outer wall; wherein the thrombectomy sheath is sized and shaped to be at least partially positioned within a vein proximal to a thrombus or other item within the vein and further configured to expand to contact the vein to secure the thrombectomy sheath within the vein; and wherein the lumen is sized and shaped to receive a device selected from the group consisting of a balloon catheter and a snare having a loop.

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Номер записи: 42
13-02-2020 дата публикации

SYSTEM FOR EFFECTING AND CONTROLLING OSCILLATORY PRESSURE WITHIN BALLOON CATHETERS FOR FATIGUE FRACTURE OF CALCULI

Номер: US20200046949A1
Автор: Chisena Robert, Gurm Hitinder S., HILDNER Matthew, Shih Albert, ZHENG Yihao
Принадлежит:

A dynamic balloon angioplasty system for applying a dynamic pressure to fracture hardened materials embedded within an elastic conduit. The system having a pressure source system outputting at least a first predetermined pressure from a pressure source outlet, and an angioplasty unit fluidly coupled to the pressure source outlet receiving at least the first predetermined pressure. The angioplasty unit having an angioplasty inflation device, an angioplasty balloon connector, and an oscillating mechanism selectively actuated to output a plurality of pressure pulses to the angioplasty balloon via a fluid communication path. A control system is configured to determine an optimal hydraulic pressure oscillation frequency and amplitude for a given procedure and output a control signal to the oscillating mechanism, and monitor a pressure signal to detect fracture of the hardened material within the elastic conduit or system failure or leakage. 1. A dynamic balloon angioplasty system for applying a dynamic pressure to fracture or modify hardened materials embedded within an elastic conduit , the dynamic balloon angioplasty system comprising:a pressure source system configured to output at least a first predetermined pressure from a pressure source outlet;an angioplasty unit being fluidly coupled to the pressure source outlet to receive at least the first predetermined pressure, the angioplasty unit having an angioplasty inflation device and a balloon connector operably coupled to and extending from the angioplasty inflation device, the balloon connector being configured to be connectable to an angioplasty balloon for delivering a plurality of pressure pulses to the angioplasty balloon;an oscillating mechanism being selectively actuated to receive pressure from the pressure source outlet and output the plurality of pressure pulses to the angioplasty balloon via a fluid communication path;a pressure transducer operably coupled to the fluid communication path, the pressure ...

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Номер записи: 43
01-03-2018 дата публикации

AXIAL LENGTHENING THROMBUS CAPTURE SYSTEM

Номер: US20180055619A1
Автор: Ngo Tung Hoang, Nguyen Duy, Nguyen Thanh Van
Принадлежит:

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions. 119-. (canceled)20. A clot capture system , comprising:a shaft;a plurality of axially spaced-apart anchors comprising a reduced configuration and an expanded configuration, wherein the plurality of axially spaced-apart anchors extend radially outward from the shaft in the expanded configuration;a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening, wherein the shape memory tubular body is compressed in a compressed configuration,wherein the shape memory tubular body is transformable to a first expanded configuration in which the first end is expanded, wherein the second end and a portion of the shape memory tubular body is compressed in the first expanded configuration, wherein the shape memory tubular body has a first expanded axial length in the first expanded configuration,wherein the shape memory tubular body is transformable to a second expanded configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein the shape memory tubular body circumscribes the plurality of axially spaced-apart anchors in the second expanded configuration.21. The clot capture system of claim 20 , wherein the plurality of axially spaced-apart anchors comprise three or more anchors.22. The clot capture system of claim 20 , wherein the plurality of axially spaced-apart anchors are coaxial.23. The clot capture system of claim 20 , wherein the plurality of axially spaced-apart anchors comprise nitinol.24. The clot capture system of claim 20 , wherein an anchor of the plurality of axially spaced-apart anchors forms an angle with an anchor pusher when expanded ...

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Номер записи: 44
01-03-2018 дата публикации

Dynamic Microvalve Protection Device

Номер: US20180055620A1
Автор: Arepally Aravind, Chomas James E., Martin John, Naglreiter Brett E., Pinchuk Bryan M., Pinchuk Leonard
Принадлежит: Surefire Medical, Inc.

An apparatus includes a delivery catheter having a deployable dynamic valve that dynamically opens and closes in response to relative fluid pressure thereabout, particularly while in an anatomical lumen. The valve is maintained in a collapsed configuration during introduction to a treatment site. The valve is adapted to automatically move from the collapsed configuration to a deployed configuration at the treatment site. 1. An endovascular device for use in a vessel having a vessel wall during an intravascular procedure , comprising:a) a catheter having a distal end, a lumen defining an inner diameter and opening at a distal orifice, and an outer diameter; and wherein once the valve is in the deployed state in the vessel, the valve is dynamically movable between an expanded valve-open configuration and a collapsed valve-closed configuration depending on a local fluid pressure about the valve such that,', 'when the fluid pressure is higher on a proximal side of the valve, the valve is in the valve-closed configuration in which the distal end of valve assumes a first diameter smaller than a diameter of the vessel such that fluid flow about the valve is permitted, and', 'when the fluid pressure is higher on a distal side of the valve, the valve is in a deployed valve-open configuration in which the distal end of the valve assumes a second diameter relatively larger than the first diameter and in which the valve is adapted to contact the vessel wall., 'b) a valve fixed to the distal end of the catheter, the valve movable into a collapsed undeployed state for delivery, and expandable from the undeployed state into a radially-expanded deployed state by a spring bias of the valve, the valve including a polymeric filter coated onto the valve such that the polymeric filter is constrained to move with the valve,'}2. The endovascular device according to claim 1 , wherein:the valve automatically collapses into the valve-closed configuration during systole and automatically ...

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Номер записи: 45
02-03-2017 дата публикации

SHOCK WAVE CATHETER SYSTEM WITH ENERGY CONTROL

Номер: US20170056035A1
Автор: Adams John M.
Принадлежит:

A system includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and first and second electrodes within the balloon arranged to carry a voltage there-across including an initial high electrical voltage at an initial low current. The initial high electrical voltage causes an electrical arc to form across the first and second electrodes within the balloon. The electrical arc causes a gas bubble within the liquid, a high current to flow through the first and second electrodes, a decrease in the initial high electrical voltage, and a mechanical shock wave within the balloon. The system further includes a power source that provides the first and second electrodes with a drive voltage that creates the initial high electrical voltage at the initial current and that terminates the drive voltage in response to the decrease in the initial high electrical voltage. 1. A method for delivering shock waves to a calcified lesion comprising:providing a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and first and second electrodes within the balloon;introducing the fluid into the balloon to inflate the balloon;applying a drive voltage pulse across the first and second electrodes to form an electrical arc within the fluid;sensing voltage across the first and second electrodes; andvarying the application of the drive voltage across the first and second electrodes in response to a change in sensed voltage.2. The method of claim 1 , wherein the varying step includes terminating the application of the drive voltage pulse.3. The method of claim 2 , wherein the application of the drive voltage pulse is terminated when the sensed voltage decreases by more than a predetermined amount.4. The method of claim 3 , wherein the ...

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Номер записи: 46
20-02-2020 дата публикации

MINIMALLY INVASIVE SURGICAL APPARATUS AND METHODS

Номер: US20200054469A1
Автор: Dickinson Robert Julian, Jain Ajay Kumar, Pacey Andrew Robert, Rothman Martin Terry
Принадлежит:

Apparatus and methods are described for performing percutaneous catheter-based interventional surgery. The apparatus comprises first and second devices that are located in adjacent body cavities, such as adjacent blood vessels, the first device being capable of transmitting a directional signal that can be received by the second device. The direction of the signal is correlated with the facility to direct therapy, such that improved accuracy in therapy placement is thereby achieved. Methods for treating patients utilising the means and apparatus are also provided. 148.-. (canceled)49. A system for treating vasculature by forming a fistula , the system comprising: a longitudinal axis;', 'an ultrasound signal transducer mounted at a non-parallel angle relative to the longitudinal axis, the ultrasound signal transducer configured to transmit an ultrasound signal at the non-parallel angle and along a directional path in a cone having position uncertainty less than 5 mm, the ultrasound signal configured to penetrate tissue outside the stenosed artery,', 'an outer sheath,', 'a lumen within the outer sheath,', 'an aperture in the outer sheath, the aperture proximal to the ultrasound signal transducer, the aperture in communication with the lumen, and', 'a needle deployable from inside the lumen to outside the lumen through the aperture and along a deployment path that is aligned with the directional path of the ultrasound signal; and, 'a launching catheter configured to be inserted in a stenosed artery, the launching catheter comprising an omnidirectional ultrasound signal receiving transducer, and', 'a reflecting cone configured to direct the ultrasound signal onto the omnidirectional ultrasound signal receiving transducer, wherein detection of the ultrasound signal by the omnidirectional ultrasound signal receiving transducer indicates that deploying the needle will exit the stenosed artery, traverse tissue between the stenosed artery and the vein, and will enter the ...

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Номер записи: 47
10-03-2016 дата публикации

Gel-forming system for removing urinary calculi and fragments thereof

Номер: US20160067373A1
Автор: Arkadiusz MIERNIK, Ingo Grunwald, Katharina Richter, Martin SCHOENTHALER
Принадлежит: Albert Ludwigs Universitaet Freiburg, Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV

Primarily described are gel-forming systems, consisting of or comprising a composition (A), comprising one or several cationically crosslinkable polymer(s), and a composition (B), comprising one or several crosslinking agent(s) for crosslinking the cationically crosslinkable polymer(s) for use in a method for removing urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, from a region of the urinary tract, more particularly a kidney, that contains urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, with the following steps: (i) providing the compositions (A) and (B), (ii) introducing the compositions (A) and (B) into a region of the urinary tract, more particularly the kidney, that contains urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, under conditions enabling crosslinking of the cationically crosslinkable polymer(s) upon contact of composition (A) with composition (B) so that a crosslinked gel is formed that partly or fully surrounds the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, (iii) removing the crosslinked gel together with the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are surrounded by it from the urinary tract, more particularly the kidney.

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Номер записи: 48
08-03-2018 дата публикации

Clot Retrieval Device for Ischemic Stroke Treatment

Номер: US20180064454A1
Автор: Losordo Michael, MA Jianlu
Принадлежит: NeuroVasc Technologies, Inc.

A clot removal device has a segment that has two main struts that serve as a frame for holding a plurality of secondary struts. Each of the two main struts has a proximal end that is connected at a proximal point of the segment and extends along a generally circumferential path, with each main strut terminating at a separate connecting point that is distal from the proximal point. The connecting points are connected to each other to form a generally tubular structure defining an inner lumen. The plurality of secondary struts forms a lattice of cells, with each cell surrounded by four secondary struts. Two generally straight distal struts are connected to the lattice of cells at a distal end of the segment, and are connected to each other to form a distal point. A distal opening is defined by the cells adjacent the distal struts, the distal opening communicating with the lumen and terminating at the proximal point. 116-. (canceled)17. A method for removing a clot or embolus from a blood vessel , comprising: the plurality of secondary struts form a lattice of cells for each segment;', 'the two main struts of the first segment having proximal ends that are connected to each other at a proximal point of the first segment, and distal ends terminating at separate connecting points that are distal from the proximal point, with the connecting points being connected to each other to form a generally tubular structure defining an inner lumen for the first segment: and', 'the two main struts of the second segment having proximal ends, each being connected to a separate one of the distal ends of the two main struts of the first segment at the connecting points, and the main struts of the second segment also having distal ends that are connected to each other in the second segment;, 'providing a clot removal device, comprising a plurality of segments that includes at least a first segment and a second segment, each segment having two main struts that serve as a supporting frame ...

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Номер записи: 49
11-03-2021 дата публикации

Devices, systems and methods to remove blood clots

Номер: US20210068852A1
Автор: Paul A. Spence
Принадлежит: Ischemicure Ltd

Systems, devices and methods for removing a blood clot ( 10 ) from a blood vessel ( 12 ). Various uses of suction pressure and positive pressure, proximal and/or distal to the blood clot ( 10 ) assist with clot dislodgement and removal. The pressure(s) may be constant and/or cycled/pulsed to assist with clot dislodgement and/or removal. Various further devices assist with separating the clot ( 10 ) from the vessel ( 12 ).

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Номер записи: 50
11-03-2021 дата публикации

Electrically enhanced retrieval of material from vessel lumens

Номер: US20210068853A1
Автор: Andy Huynh, Gaurav Girdhar, Hoai (Kevin) Nguyen
Принадлежит: COVIDIEN LP

Retrieval of material from vessel lumens can be improved by electrically enhancing attachment of the material to the thrombectomy system. The system can include a catheter having a distal portion configured to be positioned adjacent to a thrombus in a blood vessel, an electrode disposed at the distal portion of the catheter, and an interventional element configured to be delivered through a lumen of the catheter. The electrode and the interventional element are each configured to be electrically coupled to an extracorporeal power supply.

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Номер записи: 51
15-03-2018 дата публикации

More Efficiently and Effectively Removing Stenotic And Restenotic Plaque From Arteries

Номер: US20180070965A1
Автор: Kelly Thomas K., Wiita Thomas A.
Принадлежит:

Technology by which, collectively, deposits of stemotic and restenotic plaque are more efficiently and more effectively removed from arteries is disclosed, including kit and method techniques by which arterial plaque is sequentially treated through a surgically-created arterial opening, followed by sequential arterial insertion and removal of medical instruments and appliances by which a bond at the interface between the plaque and the arterial well is first disunified and destrengthened with the arterial wall materially stretched away from the plaque, after which plaque is excavated and removed and, in some instances, a novel tubular graft and encased proximal stent adheringly installed. 1. A method of excavating plaque from an artery , comprising the acts of:providing a surgically-created opening in an artery;inserting a dissecting instrument into the artery through the opening;positioning the dissecting instrument at an interface between plaque in the artery and a portion of the arterial wall;radially expanding the arterial wall a predetermined distance away from the interface while separating plaque from the arterial wall utilizing the dissecting instrument for both to thereby accurately excavate a quantity of plaque from the remaining arterial wall exactly along the interfaceremoving the excavated plaque from the artery through the opening.2. A method of excavating plaque from an artery , comprising the acts of;positioning a dissecting instrument at an interface between plaque and an adjacent part of an arterial wall;expanding the arterial wall outwardly beyond the limits of the plaque to materially stretch the arterial wall while displacing the instrument along the interface and accurately severing the plaque from the remaining arterial wall while the adjacent arterial is being stretched.3. A method according to wherein the expanding act is performed by the dissecting instrument.4. A method according to wherein the expanding act is performed by other than the ...

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Номер записи: 52
16-03-2017 дата публикации

MEDICAL MICRO ROBOT AND MICRO ROBOT SYSTEM HAVING THE SAME

Номер: US20170071622A1
Автор: JANG Gun Hee, JEON Seung Mun
Принадлежит:

The present invention provides a micro robot including: a drilling body which has a drilling tip formed at an end thereof; a spiral coupling body which has a magnet disposed therein, and is spirally coupled to an outer circumference of the drilling body; and a system control unit which allows the drilling body and the spiral coupling body to spirally move simultaneously or allows the spiral coupling body to spirally move around the drilling body by providing rotational magnetic field to the magnet. In addition, the present invention also provides a micro robot system including the micro robot. 1. A micro robot comprising:a drilling body which has a drilling tip formed at an end thereof;a spiral coupling body which has a magnet disposed therein, and is spirally coupled to an outer circumference of the drilling body; anda system control unit which allows the drilling body and the spiral coupling body to spirally move simultaneously or allows the spiral coupling body to spirally move around the drilling body by providing rotational magnetic field to the magnet.2. The micro robot of claim 1 , wherein a spiral protrusion claim 1 , which is spirally coupled to the spiral coupling body claim 1 , is formed on the outer circumference of the drilling body.3. The micro robot of claim 2 , wherein a medicine accommodating space claim 2 , which has a hollow shape and accommodates a medicine claim 2 , is formed in the drilling body claim 2 , and a medicine injection hole through which the accommodated medicine is injected to the outside is formed at an end portion of the drilling tip.4. The micro robot of claim 3 , wherein the spiral coupling body includes:a piston body which is disposed to be fitted into the medicine accommodating space in order to pump the medicine; anda spiral coil which is formed at an end portion of the piston body and spirally coupled to the spiral protrusion.5. The micro robot of claim 4 , wherein a magnet slot into which the magnet is fitted and installed ...

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Номер записи: 53
07-03-2019 дата публикации

DEVICE FOR THERAPEUTIC DELIVERY OF MEDICAL FLUID

Номер: US20190070362A1
Автор: Lynch Patrick
Принадлежит:

The present invention will provide a medical device that can properly regulate the working pressure of a highly pressurized gas for delivering therapeutic agents at a relatively constant flow rate during the entire course of infusion while also maintaining the integrity of the operating room and reducing risks involved with therapeutic agents. This is accomplished utilizing a pressure control assembly along with a syringe assembly or self-contained fluid chamber to administer therapeutic agents to patents in a controlled and safe manner by incorporating pressurized gas. 1. A therapeutic liquid dispensing device comprising:a therapeutic fluid chamber adapted to dispense liquid;a working pressure chamber adapted to provide a working pressure at or below a reference pressure, said working pressure chamber mechanically connected to said therapeutic fluid chamber;a high-pressure chamber adapted to provide pressurized gas from the high-pressure chamber to the working pressure chamber;a pressure control device assembly positioned between said high-pressure chamber and said working pressure chamber, said pressure control device assembly adapted to regulate the working pressure and provide a constant working pressure inside the working pressure chamber to a reference pressure for the entire duration of liquid dispensation.2. The device of claim 1 , further comprising an activation valve in fluid connection between the high pressure chamber and working pressure chamber claim 1 , said activation valve adapted to actuate the pressurized gas from the high-pressure chamber to the working pressure chamber at time of liquid dispensation claim 1 ,3. The device of claim 2 , wherein said activation valve further comprises fluidly connecting the working chamber to atmosphere for purposes of venting the accumulated pressure within the working pressure chamber during filling of therapeutic fluid chamber or terminating positive pressure to the working chamber.4. The device of claim 1 , ...

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Номер записи: 54
18-03-2021 дата публикации

ARGON COMBINED WITH THROMBECTOMY IN THE EVENT OF ISCHAEMIC STROKE

Номер: US20210077767A1
Автор: Billoet Catherine, Brochier Thomas, Farjot Géraldine, Velly Lionel
Принадлежит:

The invention relates to an inhalable gaseous medicament containing argon gas for use in combination with a mechanical thrombectomy for treating, reducing or resorbing brain lesions subsequent to an ischaemic stroke in an individual. Preferably, the proportion by volume of argon is between 30 and 79%. The mechanical thrombectomy can be accompanied by a drug-based thrombolysis to dissolve the clot and to thin the blood of the patient. 2. The method according to claim 1 , characterized in that the gaseous medicament containing Argon is between 30 and 79% by volume Argon.3. The method according to claim 1 , characterized in that the gaseous medicament containing Argon is between 40 and 70% Argon.4. The method according to characterized in that the gaseous medicament containing Argon is mixed with a gas containing at least 21% by volume of oxygen.5. The method according to claim 4 , characterized in that gaseous medicament containing Argon is mixed with a gas containing 35 to 50% of oxygen.6. The method according to claim 5 , characterized in that a final proportion by volume of Argon is equal to 60% and the proportion by volume of oxygen is equal to 40%.7. The method according to claim 1 , characterized in that the gaseous medicament containing Argon is in a form suitable for inhaled administration by the nasal claim 1 , buccal or pharyngeal route.8. The method according to claim 1 , characterized in that the administration of the gaseous medicament containing Argon by inhalation is continued after a reperfusion subsequent to the mechanical extraction of at least one portion of the blood clot resulting from the ischaemic stroke.9. The method according to claim 8 , characterized in that the administration of the gaseous medicament containing Argon by inhalation is continued for at least 30 minutes after reperfusion.10. The method according to claim 1 , characterized in that the gaseous medicament containing Argon is packaged in a pressurized gas container.11. The method ...

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Номер записи: 55
19-03-2015 дата публикации

Aspiration Thrombectomy Catheter System, And Associated Methods

Номер: US20150080853A1
Автор: Ron Smalling
Принадлежит: Smalling Medical Ventures LLC

An aspiration thrombectomy catheter system includes an aspirator and an aspiration catheter for insertion in a blood vessel. The catheter has a shaft with a proximal end for connection with the aspirator and a tapering distal end with a tip for insertion in the vessel. A plurality of aspiration ports are arranged in sets along the tapering distal end, for aspirating thrombus from the vessel. At least one aspiration lumens within the shaft conducts thrombus from the vessel, through the aspiration ports, to the aspirator. Variably sized or shaped ports provide differing aspiration vectors for enhanced thrombus removal. The aspiration thrombectomy catheter additionally provides for uniform drug dispersion at a thrombotic area, alone or in combination with aspiration of the thrombus. In the event of an adverse reaction, drug dosage may be easily reduced by aspirating dispersed drugs back into the catheter.

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Номер записи: 56
19-03-2015 дата публикации

System and Methods Which Remove Material From Blood Vessel Walls

Номер: US20150080922A1
Автор: Rainer Meinke, Sasha Ishmael
Принадлежит: Advanced Magnet Lab Inc

Systems and methods for removing plaque from blood vessels by applying constant or time varying magnetic or electrical fields. In one embodiment a system includes winding configurations positioned about a central axis along which a body region may be placed. Each winding configuration generates a magnetic field in a direction which passes through the body region. A first winding configuration generates a first magnetic field component perpendicular to a second magnetic field component generated by a second winding configuration. In a related method for removing a deposit of plaque from a position along a wall of a blood vessel a magnetic field is applied which has a net direction predominantly orthogonal to the direction of the flow of blood through the vessel.

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Номер записи: 57
22-03-2018 дата публикации

C-Arm Field Generating Apparatus For Removing Material From Blood Vessel Walls

Номер: US20180078269A1
Автор: Ishmael Sasha, Meinke Rainer
Принадлежит: Advanced Magnet Lab, Inc.

Systems and methods for removing plaque from blood vessels by applying constant or time varying magnetic or electrical fields. In one embodiment a system includes winding configurations positioned about a central axis along which a body region may be placed. Each winding configuration generates a magnetic field in a direction which passes through the body region. A first winding configuration generates a first magnetic field component perpendicular to a second magnetic field component generated by a second winding configuration. In a related method for removing a deposit of plaque from a position along a wall of a blood vessel a magnetic field is applied which has a net direction predominantly orthogonal to the direction of the flow of blood through the vessel. 1. A system for removing plaque from a blood vessel , comprising:first and second components which generate a field;a C-arm configured to support the components in spaced apart relation while a patient is disposed between the components and along a first axis; anda chassis supporting the C-arm, wherein the C-arm is moveable about the axis to rotate the components about the first axis.2. The system of wherein the components are coils operable to generate a magnetic field in a direction perpendicular to the first axis.3. The system of wherein the components are plates operable to generate an electric field in a direction perpendicular to the first axis.4. The system of wherein the C-arm is mounted on a moveable chassis to provide movement of the components in directions parallel to the first axis. This application is filed as a divisional of U.S. application Ser. No. 13/982,784 filed in the USPTO on Jul. 31, 2013 issuing on Nov. 28, 2017 as U.S. Pat. No. 9,826,996, which was a National Stage application claiming priority to PCT Application No. PCT/US2012/023271 filed Jan. 31, 2012, which claimed priority to U.S. Provisional Application No. 61/438,198 filed Jan. 31, 2011; this application is also a continuation ...

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Номер записи: 58
22-03-2018 дата публикации

METHOD AND DEVICE FOR INFUSION OF PHARMACOLOGIC AGENTS AND THROMBUS ASPIRATION IN ARTERY

Номер: US20180078685A1
Автор: ABBOUD Marwan, CHARRON Thierry, LEBLANC Aime-Robert, ROUSSEAU Guy, Santoianni Domenic
Принадлежит:

A catheter device and method for treating an artery with thrombus, the catheter comprising an inflatable member. A carrier catheter has a proximal end and a distal end adapted to be inserted percutaneously into an artery, the carrier catheter having a tubular body adjacent to a rear end of the inflatable member. An inflating tube passes through the tubular body and having an open front end in fluid communication with the inflatable member to inflate same. An infusion tube is adapted to infuse pharmacologic agents, the infusion tube passing through the tubular body and having an open front end extending beyond the inflatable member. An aspiration tube is adapted to aspire the thrombus, the aspiration tube passing through the tubular body and having an open front end between the carrier catheter and the inflatable member. 1. A method for treating an artery having a thrombus comprising: percutaneously positioning a catheter with an infusion tube in the artery proximally to the thrombus; passing a tip of the infusion tube through the thrombus; and infusing at least one pharmacologic agent distally to the thrombus via the infusion tube.2. The method according to claim 1 , wherein positioning the catheter comprises positioning an inflatable member of the catheter proximally to the thrombus claim 1 , and further comprising inflating the inflatable member proximally to the thrombus.3. The method according to claim 2 , wherein inflating the inflatable member proximally to the thrombus is performed prior to infusing at least one pharmacologic agent distally to the thrombus.4. The method according to claim 1 , wherein positioning the catheter further comprises positioning an aspiration tube of the catheter proximally to the thrombus claim 1 , the aspiration tube being proximal to the inflatable member.5. The method according to claim 4 , further comprising performing an aspiration via the aspiration tube while deflating the inflatable member to aspire the thrombus.6. The ...

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Номер записи: 59
23-03-2017 дата публикации

GLAND OR DUCT DIAGNOSTIC AND TREATMENT METHODS AND RELATED APPARATUS

Номер: US20170079842A1
Автор: Maskin Steven L.
Принадлежит: MGD Innovations, LLC

A method is provided for treating a gland or duct of a patient. In a particular embodiment, an obstruction in a gland or duct and the orifice thereof can be alleviated; in another, a substance can be injected thereinto; in yet another, the gland can be aspirated. The method includes the step of inserting an elongated probe into a gland or duct via an orifice thereinto. In some embodiments the probe can have a longitudinal lumen therethrough, with at least one distal hole through the probe wall in fluid communication with the lumen. The lumen can be used in concert with a source of suction for removing debris from the gland or duct, and/or with a source of a fluid and pumping means, for injecting a substance into the gland or duct. 1. A device for treating a gland or duct of a patient comprising:a probe having an elongated distal end with an outer diameter of approximately 150 μm or less and a length of approximately 6 mm or less.2. The device recited in claim 1 , wherein the probe has a longitudinal lumen extending therealong defined by a probe wall and a distal hole through the probe wall in fluid communication with the lumen claim 1 , the distal hole positioned in the probe distal end.3. The device recited in claim 2 , further comprising a pump element in fluid communication with the lumen for pumping fluid through the lumen and out the distal hole into the meibomian gland.4. The device recited in claim 2 , wherein the distal hole comprises a plurality of distal holes.5. The device recited in claim 2 , wherein the probe lumen comprises a first lumen and a second lumen claim 2 , and the distal hole comprises a first distal hole in fluid communication with the first lumen and a second distal hole in fluid communication with the second lumen claim 2 , such that suction can applied to the first lumen while fluid is injected through the second lumen.6. The device recited in claim 2 , further comprising an elongated element positioned at least partially within the probe ...

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Номер записи: 60
31-03-2022 дата публикации

Ultrasound Catheter Having Improved Distal End

Номер: US20220096793A1
Автор: Nita Henry
Принадлежит: FLOWCARDIA, INC.

An ultrasonic catheter has a flexible catheter body having a main lumen, a catheter body interior wall, and a catheter body open distal end. The ultrasonic catheter has an ultrasound transmission member disposed in the main lumen. The ultrasonic catheter has a distal tip that is disposed on the ultrasound transmission member distal end. The ultrasonic catheter includes an intermediate member having an intermediate member open proximal end, an intermediate member open distal end, and an intermediate member interior wall forming a hollow interior. The intermediate member is attached to the catheter body interior wall at the catheter body open distal end. The hollow interior has a smallest inner diameter adjacent the intermediate member open proximal end. The hollow interior configured to overlap the ultrasound transmission member distal end and at least a portion of the distal tip. 120-. (canceled)21. An ultrasonic catheter comprising:a flexible catheter body having a main lumen, a catheter body interior wall, and an catheter body open distal end;an ultrasound transmission member disposed in the main lumen, the ultrasound transmission member having a proximal end that is configured to connect to a generating device and a ultrasound transmission member distal end;a distal tip disposed on the ultrasound transmission member distal end; andan intermediate member having an intermediate member open proximal end, an intermediate member open distal end, and an intermediate member interior wall forming a hollow interior, the hollow interior extends from the intermediate member open proximal end to the intermediate member open distal end, the intermediate member attached to the catheter body interior wall at the catheter body open distal end, the hollow interior having a smallest inner diameter adjacent the intermediate member open proximal end, the hollow interior configured to overlap the ultrasound transmission member distal end and at least a portion of the distal tip.22. ...

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Номер записи: 61
19-03-2020 дата публикации

INTRA-VENTRICULAR INFUSION AND EVACUATION CATHETER FOR TREATMENT OF INTRACEREBRAL HEMORRHAGE (ICH)

Номер: US20200085453A1
Автор: Porter Stephen, Schabert Jon
Принадлежит:

An infusion/aspiration catheter comprises an elongate catheter body, at least one infusion lumen, and an aspiration lumen extending between a proximal end and a distal end of the catheter body. The aspiration lumen terminates in a distal fluid port at the distal end of the catheter body. The catheter further comprises arms respectively having proximal ends affixed together at the distal end of catheter body. The distal fluid port of the catheter body is between the proximal ends of the arms, the arms have lumens in fluid communication with the infusion lumen(s), and each of the arms has fluid ports in fluid communication with the lumen of the respective arm. The catheter further comprises at least one infusion connector in fluid communication with the infusion lumen(s), and an aspiration connector in fluid communication with the aspiration lumen(s). 1. An infusion/aspiration catheter , comprising:an elongate catheter body having a proximal end, a distal end, at least one infusion lumen and an aspiration lumen extending between the proximal end and the distal end, the aspiration lumen terminating in a distal fluid port at the distal end of the elongate catheter body;a plurality of arms respectively having proximal ends affixed together at the distal end of elongate catheter body, the distal fluid port of the elongate catheter body being between the proximal ends of the plurality of arms, the arms having lumens in fluid communication with the at least one infusion lumen, each of the arms having at least one fluid port in fluid communication with the lumen of the respective arm;at least one infusion connector affixed to the proximal end of the elongate catheter body in fluid communication with the at least one infusion lumen; andan aspiration connector affixed to the proximal end of the elongate catheter body in fluid communication with the at least one aspiration lumen.2. The infusion/aspiration catheter of claim 1 , wherein the at least one infusion lumen comprises a ...

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Номер записи: 62
19-03-2020 дата публикации

SHOCK WAVE CATHETER SYSTEM WITH ENERGY CONTROL

Номер: US20200085459A1
Автор: Adams John M.
Принадлежит:

A system includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and first and second electrodes within the balloon arranged to carry a voltage there-across including an initial high electrical voltage at an initial low current. The initial high electrical voltage causes an electrical arc to form across the first and second electrodes within the balloon. The electrical arc causes a gas bubble within the liquid, a high current to flow through the first and second electrodes, a decrease in the initial high electrical voltage, and a mechanical shock wave within the balloon. The system further includes a power source that provides the first and second electrodes with a drive voltage that creates the initial high electrical voltage at the initial current and that terminates the drive voltage in response to the decrease in the initial high electrical voltage. 1. A method for controlling delivery of shock waves to treat calcified lesions in the wall of a blood vessel of a patient , the method comprising:positioning an angioplasty catheter device within the blood vessel of the patient, the catheter device comprising an angioplasty balloon surrounding an arc generator, the angioplasty catheter including a central guide wire sheath for receiving a guide wire therein;inflating the angioplasty balloon of the catheter device within the vessel with a conductive liquid; and the arc generator comprises a first electrode and a second electrode, and', applying a voltage to the arc generator,', 'monitoring signals representing values of the voltage between the first electrode and the second electrode, wherein the signals are generated by a voltage sensor, and', 'terminating the voltage to the arc generator to complete the respective pulse, wherein terminating comprises, 'delivering the plurality of voltage pulses comprises, for each pulse of the ...

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Номер записи: 63
19-03-2020 дата публикации

INTRA-VENTRICULAR INFUSION AND EVACUATION CATHETER FOR TREATMENT OF INTRACEREBRAL HEMORRHAGE (ICH)

Номер: US20200086083A1
Автор: Porter Stephen, Schabert Jon
Принадлежит:

A method of treating an anatomical cavity of a patient comprises introducing an infusion/aspiration catheter into the patient, such that a plurality of arms of the catheter reside within the anatomical cavity, delivering a fluid into the at least one of a connector, such that fluid exits the at least one fluid port of at least one of the arms, thereby infusing the anatomical cavity with the fluid, and aspirating the fluid into the at least one fluid port of at least one of the arms, such that the fluid exits the connector(s). 1. A method of treating an anatomical cavity of a patient using an infusion/aspiration catheter , the infusion/aspiration catheter comprising an elongate catheter body having a proximal end , a distal end , and a plurality of independent lumens extending between the proximal end and the distal end , a plurality of arms respectively having proximal ends affixed together at the distal end of elongate catheter body , each of the arms having a lumen in fluid communication with a respective one of the independent lumens of the elongate catheter body , each of the arms having at least one fluid port in fluid communication with the lumen of the respective arm , and at least one connector affixed to the proximal end of the elongate catheter body in fluid communication with the independent lumens of the elongate catheter body , the method comprising:introducing the infusion/aspiration catheter into the patient, such that the plurality of arms reside within the anatomical cavity;delivering a fluid into the at least one of the connector, such that fluid exits the at least one fluid port of at least one of the arms, thereby infusing the anatomical cavity with the fluid; andaspirating the fluid into the at least one fluid port of at least one of the arms, such that the fluid exits the at least one connector.2. The method of claim 1 , wherein the at least one connector comprises a plurality of connectors in fluid communication with the independent lumens of ...

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Номер записи: 64
19-06-2014 дата публикации

Apparatus and methods for clot dissolution

Номер: US20140171911A1
Автор: Alexander Khairkhahan, Denise Demarais, Dino De Cicco, Kelvin Ning, Michael A. Evans, Tyler Jon Strang
Принадлежит: COVIDIEN LP

Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.

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Номер записи: 65
05-04-2018 дата публикации

ENHANCED CROSS STREAM MECHANICAL THROMBECTOMY CATHETER

Номер: US20180092658A1
Автор: Bonnette Michael J., Kozak Debra M., Schrom Michael, Thor Eric J.
Принадлежит: BOSTON SCIENTIFIC LIMITED

A thrombectomy catheter includes a catheter body having a catheter lumen. An outflow orifice is positioned along a catheter perimeter. A fluid jet emanator communicates with a high pressure tube. The fluid jet emanator includes at least one jet orifice for directing a fluid jet from the fluid jet emanator through the catheter lumen toward the outflow orifice. The fluid jet emanator provides a jet stream from the catheter body through the outflow orifice. The jet stream includes first and second stream portions. An entrainment fluid flow circuit includes at least the first stream portion, and the entrainment fluid flow circuit entrains particulate and macerates the particulate therein. An exhaust fluid flow path includes the second stream portion, and the exhaust fluid flow path draws entrained particulate from the entrainment fluid flow circuit at a location exterior to the catheter body and directs it toward the catheter proximal portion. 1. A medical device , comprising:an elongate tubular member, wherein the tubular member includes a proximal portion, a distal portion and a lumen extending therein;a high pressure tube extending within a lumen of the tubular member;a fluid jet emanator coupled to the high pressure tube, the fluid jet emanator having at least one jet orifice for directing a first fluid jet through the lumen of the tubular member;an inflow orifice located on the distal portion of the tubular member;an outflow orifice located on the distal portion of the tubular member;a deflector positioned within the lumen of the tubular member, the deflector configured to direct the first fluid jet out of the outflow orifice.2. The medical device of claim 1 , wherein the deflector is positioned distal to the inflow orifice.3. The medical device of claim 1 , wherein the deflector is positioned proximal to the inflow orifice.4. The medical device of claim 1 , wherein the deflector includes a deflector face claim 1 , and wherein the deflector face faces the at least ...

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Номер записи: 66
05-04-2018 дата публикации

APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS

Номер: US20180093080A1
Автор: Betelia Ray, Domingo Juan, Dreher James H., Fernandez Lucas, Krolik Jeffrey A., Mirzaee Daryush, WATANABE Gwendolyn
Принадлежит:

An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including proximal and distal ends, a lumen extending there between, and a balloon on the distal end. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The valve may be biased to be closed, e.g., by a spring element disposed within the balloon. Optionally, the apparatus also includes an actuator for expanding a helical member within the balloon interior, e.g., either before or after expanding the balloon, such that the helical member and balloon may adopt an expanded helical shape for removing material within a body lumen. 1. An apparatus for treating a body lumen , comprising:an elongate outer member including a proximal end, a distal end sized for introduction into a body lumen, and a first lumen extending between the proximal end and an outlet in the distal end;an inner member slidably disposed within the first lumen and having a cross-section smaller than the first lumen such that an annular lumen is defined between the outer and inner members between the outer member proximal end and the outlet, the inner member comprising a proximal end adjacent the outer member proximal end, and a distal end adjacent the outer member distal end;an expandable balloon comprising a proximal end secured to the outer member distal end and a distal end secured to the outer member distal end distal to the proximal end, the balloon comprising an interior communicating with the first lumen via one or more openings in the outer member distal end;a sealing member on the inner member distal end, the inner member being movable between a first position wherein the sealing member is spaced from the outlet such ...

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Номер записи: 67
28-03-2019 дата публикации

CATHETER WITH MULTIPLE ULTRASOUND RADIATING MEMBERS

Номер: US20190091458A1
Автор: ABRAHAMSON TIM, BARRERE WM. GERRIT, Cohen Amy, Genstler Curtis, KEILMAN GEORGE, OLIVER LEONARD R., PESKIN NATALYA, Wilcox Robert L., Wilson Richard R.
Принадлежит:

A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The ultrasonic catheter system comprises a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end, a fluid delivery lumen, at least one ultrasound radiating element positioned in the treatment zone, wiring electrically coupled to the at least one ultrasound radiating element and extending through the tubular body and terminating at a connector, and a control system comprising external circuitry and an isolation pod that is configured to be electrically connected to the connector, the isolation pod being positioned between the tubular body and the external system and comprising an isolation barrier and circuitry for driving the ultrasound radiating element. 1. (canceled)2. A catheter system for delivering ultrasonic energy to a treatment site , the catheter system comprising:a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end; and an electrical conductor, having a first flat portion and a second flat portion,', 'a first ultrasound transducer having a first portion, and', 'a second ultrasound transducer having a second portion;, 'an ultrasonic assembly positioned within the treatment zone, the ultrasonic assembly comprisingwherein the first portion of the first ultrasound transducer is mounted to the first flat portion of the electrical conductor and wherein the second portion of the second ultrasound transducer is mounted to the second flat portion of the electrical conductor.3. The catheter system of claim 2 , wherein the first portion of the first transducer and the second portion of the second transducer are mounted to the electrical conductor.4. The catheter system of claim 2 , wherein the first portion of the first transducer and the second portion of the second transducer are substantially ...

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Номер записи: 68
26-06-2014 дата публикации

Ultrasound transducer and uses thereof

Номер: US20140180197A1
Автор: Ariel Sverdlik, Or Shabtay
Принадлежит: Cardiosonic Ltd

According to some embodiments there is provided a method for controlling a treatment effect on blood vessel tissue during an ultrasonic treatment, the method comprising positioning an ultrasonic transducer device in the blood vessel lumen; controlling a treatment effect by controlling fluid flow, wherein controlling comprises deploying a fluid restrictor at a location relative to the transducer effective to block at least a portion of fluid flowing upstream, downstream or adjacent the transducer. According to some embodiments there is provided an ultrasonic transducer device sized for placement in a body lumen, and comprising a fluid restrictor effective to block at least a portion of fluid flowing upstream, downstream or adjacent the transducer. In some embodiments, the fluid is blood.

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Номер записи: 69
26-03-2020 дата публикации

METHOD AND APPARATUS FOR DIAGNOSIS AND TREATMENT OF MICROVASCULAR DYSFUNCTION

Номер: US20200093991A1
Автор: Hoem Jon Helge, Rothman Martin T., Schwartz Robert S.
Принадлежит:

Methods and devices for the diagnosis and treatment of microvascular dysfunction, such as microvascular obstruction (MVO) and other dysfunctional diseases of the microvasculature of many organs, including the heart. The present subject matter provides novel devices and methods to successfully diagnose, restore patency, open and preserve flow, and limit reperfusion injury in organs and cases with microvascular dysfunction. The present subject matter provides apparatus and method to detect, measure and treat microvascular dysfunction in real time during scenarios such as invasive angiographic/therapeutic procedures. Such procedures include therapy for organ systems including the heart (acute myocardial infarction—primary percutaneous coronary intervention (PPCI)), brain stroke (CVA), bowel ischemia/infarction, pulmonary emboli/infarction, critical limb ischemia/infarction, renal ischemia/infarction, and others. The present subject matter provides various systems including an infusion and sensing catheter, diagnostic agents, therapeutic agents, and a control console with specialized algorithms to diagnose and treat microvascular dysfunction, such as MVO, in real-time with real-time operator feedback for interventional procedures. 1. A method for measuring microvascular dysfunction in an organ or limb using apparatus for providing controlled flow infusion of at least a first solution to a portion of a vessel for assessment of microvascular function and for providing a second solution to the vessel for therapeutic benefit of the microvascular function , wherein the first solution is different than the second solution.2. The method of claim 1 , wherein the first solution is a Newtonian fluid chosen to enhance linearity of the flow to better assess microvascular parameters.3. The method of claim 1 , wherein the first solution lacks oxygenation to control hypoxia.4. The method of claim 1 , wherein the first solution lacks oxygenation to vasodilate the microvasculature.5. ...

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Номер записи: 70
12-04-2018 дата публикации

HYDRAULIC DISPLACEMENT AND REMOVAL OF THROMBUS CLOTS, AND CATHETERS FOR PERFORMING HYDRAULIC DISPLACEMENT

Номер: US20180098778A1
Автор: Ogle Matthew F.
Принадлежит:

Clot removal from a patient's vessel, such as an artery, are described using aspiration and hydraulic forces supporting the removal process. Hydraulic forces can be generated by occluding the vessel distal to the clot and delivering liquid between the clot and the occlusive device. The aspiration catheter is positioned proximal to the clot. Catheters designed to facilitate the delivery of hydraulic forces can be based on single lumen designs or dual lumen designs. The catheters may have a fixed internal wire, or in some embodiments the catheters can ride over a wire with a valve/seal positioned to restrict flow into or out from the guide lumen such that the guide lumen can further function for balloon inflation and/or for infusion of liquid. 1. A method for removing a clot from a patient's vessel , the method comprising:occluding the vessel with an occluding element distal to the clot;infusing liquid between the clot and the occluding element; andaspirating liquid from the vessel proximal to the clot with at least some temporal overlap of infusing and aspirating to induce hydraulic forces against the clot.2. The method of wherein the occluding element comprises a balloon and wherein the balloon is deployed distal to the clot to occlude the vessel prior to infusing the liquid.3. The method of wherein aspiration for aspirating liquid is provided by an aspiration catheter delivered over a catheter supporting the occluding element.4. The method of wherein the vessel is a cerebral artery.5. The method of wherein the distal end of an aspiration catheter is within the cerebral arteries.6. The method of wherein the occlusive element comprises a balloon supported by an associated balloon catheter and wherein a microcatheter is located over the balloon catheter with its distal opening distal to the clot and from about 0.25 cc to about 25 cc of infusion liquid is delivered from the microcatheter.7. The method of wherein the occlusive element comprises a balloon supported by an ...

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Номер записи: 71
16-04-2015 дата публикации

LAPAROSCOPIC DEVICE

Номер: US20150105791A1
Автор: Truckai Csaba
Принадлежит: Hermes Innovations, LLC

A medical instrument includes a tubular cutter extending along an axis and having a windowed outer sleeve and a moveable inner cutting sleeve. An ultrasound transducer is operatively coupled to the inner cutting sleeve in order to induce motion in the inner cutting sleeve to enhance cutting or resection of tissue by the inner cutting sleeve as it is reciprocated or otherwise moved past the cutting window. The instrument typically will include a motor drive configured to reciprocate and/or rotate the inner cutting sleeve relative to the windowed outer sleeve, usually at a reciprocation rate between 1 and 10 Hz. 1. A medical instrument comprising:a tubular cutter extending along an axis and having a windowed outer sleeve and a moveable inner cutting sleeve; andan ultrasound transducer operatively coupled to the inner cutting sleeve.2. The instrument of further comprising a motor drive configured to reciprocate the inner cutting sleeve relative to the windowed outer sleeve.3. The instrument of wherein the motor drive reciprocates the inner cutting sleeve at a reciprocation rate between 1 and 10 Hz.4. The instrument of wherein the ultrasound transducer is configured to cause at least one of axial motion and rotational motion in the distal end of the inner cutting sleeve.5. The instrument of wherein a dimension between the ultrasound transducer and the distal end of the inner sleeve is selected to optimize at least one of axial motion and rotational motion in the distal end of the inner cutting sleeve.6. The instrument of further comprising at least a second ultrasound transducer claim 1 , wherein first and second ultrasound transducers are configured to cause axial and rotational motion in the distal end of the inner sleeve.7. The instrument of wherein the ultrasound transducer is removably secured to a handle portion of the tubular cutter.8. The instrument of further comprising a negative pressure source coupled to a tissue extraction lumen in the tubular cutter.9. The ...

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Номер записи: 72
08-04-2021 дата публикации

ROTARY EMBOLECTOMY DEVICE

Номер: US20210100581A1
Автор: Dao Duc, GILLILAND Charles, HICKMAN Kurt, RAO Tanvi, VALDMAN Melissa
Принадлежит:

Disclosed herein is a rotary embolectomy device. The device includes a rotatable bit which contacts a blood clot within a cannula, thereby disintegrating the clot. The clot can be removed by means of suction, complete disintegration, or a collecting basket. 1. A rotary embolectomy device , comprising:a rotatable driveshaft having a distal end and proximate end;a cutting bit non-rotatably coupled to or adjacent the distal end of the driveshaft;a rotational actuator coupled to or adjacent the proximate end of the driveshaft;at least one circular stabilizer rotatably coupled to the driveshaft between to the cutting bit and rotational actuator.2. The device according to claim 1 , wherein an outer circumference of the stabilizer is greater than or equal to an outer circumference of the cutting bit.3. The device according to claim 1 , wherein the cutting bit comprises one or more sharp edges.4. The device according to claim 1 , wherein the cutting bit comprises:a central shaft non-rotatably coupled to the driveshaft,a boring head centered on the central shaft, said boring head having a greater circumference than a circumference of the central shaft;an outer wall extending along the circumference of the boring head, said outer wall having one or more channels; anda cutting edge extending diametrically across the circular cross-section of the boring head, said cutting edge contacting the outer wall at a location immediately adjacent to the channel.5. The device according to claim 1 , wherein the cutting bit comprises a spade bit claim 1 , a twist bit claim 1 , a step bit claim 1 , or a center bit.6. The device according to claim 1 , wherein the stabilizer comprises:an annular outer portion comprising an outer surface and an inner surface;an annular inner portion comprising an outer surface and an inner surface defining a loop, wherein the driveshaft is disposed through the loop; andat least one spoke extending radially between the inner surface of the outer portion and the ...

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Номер записи: 73
04-04-2019 дата публикации

AXIAL LENGTHENING THROMBUS CAPTURE SYSTEM

Номер: US20190099194A1
Автор: Ngo Tung Hoang, Nguyen Duy, Nguyen Thanh Van
Принадлежит:

Disclosed herein are systems and methods to remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions. 1. A clot capture system , comprising:a first, outer tubular shaft comprising a central lumen, the first outer tubular shaft comprising a proximal portion and a distal portion, the distal portion more radially expandable than the proximal portion;a second tubular shaft configured to be positioned within the central lumen of the first shaft,;a third tubular shaft configured to be positioned within a central lumen of the second shaft;a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having a proximal-facing opening and a ring-shaped capture guide attached to a circumference of the proximal-facing opening, the capture guide operably attached to the second tubular shaft, the second end attached to an outer wall of the third tubular shaft,wherein the shape memory tubular body is compressed within the central lumen of the second tubular shaft in a first delivery configuration,wherein the shape memory tubular body is transformable to a second configuration in which the first end and the capture guide is radially expanded but the second end and a majority of the shape memory tubular body remains radially compressed within the central lumen of the second tubular shaft and the second end is positioned proximal to the first end and the shape memory tubular mesh body has a first expanded axial length,wherein the shape memory tubular body is transformable to a third configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein a width of the shape memory tubular shaft along its second expanded axial length is substantially the same as a width ...

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Номер записи: 74
26-04-2018 дата публикации

MEDICAL GUIDE WIRE DEVICE FOR ENDOVASCULAR-INTRALUMINAL DEVICES

Номер: US20180110532A1
Автор: Gast Thomas
Принадлежит:

A medical guide wire device includes a base wire, a first accessory wire, and a guiding device configured to be removably coupled to the base and first accessory wires. The base wire has a first proximal end, a first distal end, a longitudinal length extending therebetween, and a flexible portion near the first distal end. The first accessory wire has a second proximal end, a second distal end, a longitudinal length extending therebetween, and a flexible portion near the second distal end. The second distal end of the first accessory wire is coupled to the base wire at a distance spaced apart from the first distal end. Upon actuating the guiding device, the flexible portion of the base wire and the flexible portion of the first accessory wire form a curve at the first distal end of the base wire and the second distal end of the first accessory wire. 1. A medical guide wire device , comprising:a base wire having a first proximal end, a first distal end, a longitudinal length extending therebetween, and a flexible portion near the first distal end;a first accessory wire having a second proximal end, a second distal end, a longitudinal length extending therebetween, and a flexible portion near the second distal end, the second distal end of the first accessory wire being coupled to the base wire at a distance spaced apart from the first distal end; anda guiding device configured to be removably coupled to the base wire and the first accessory wire;wherein upon actuating the guiding device, the flexible portion of the base wire and the flexible portion of the first accessory wire form a curve at the first distal end of the base wire and the second distal end of the first accessory wire.2. The medical guide wire device of claim 1 , wherein the guiding device comprises:a first clamping device having a first clamping portion and a first guiding portion, wherein the first clamping portion is adapted to be removably coupled to the base wire, anda second clamping device ...

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Номер записи: 75
26-04-2018 дата публикации

INFUSION, DILATION AND ASPIRATION CATHETER (IDAC)

Номер: US20180110533A1
Автор: HORAK Gerhard-Friedrich
Принадлежит:

A system () comprises an aspiration catheter (), which is guided by way of a guidewire () to a thrombotic point in a blood vessel. A collapsed infusion balloon () is located inside the aspiration catheter (), which has an interior/inner volume () delimited by a wall (), and a delivery catheter (). The delivery catheter is intended for delivering saline solution (salt solution) for rinsing or for delivering thrombolytic medication into the interior . The balloon comprises a plurality of openings which have a diameter between 10 μm and 100 μm in order to enable an atraumatic administration of fluid. 1. A system for removing thrombotic material from a blood vessel comprising an aspiration catheter and an infusion member , wherein the infusion member has a delivery catheter configured for delivering a fluid and an expandable balloon connected to the delivery catheter , wherein the balloon has at least one of openings and a permeable wall region or a semi-permeable wall region through which the fluid can pass , whereinthe infusion member can be movably accommodated in and moved through a first lumen of the aspiration catheter.2. The system in accordance with claim 1 , wherein the openings and the permeable wall region or the semi-permeable wall region claim 1 , respectively claim 1 , are configured such that atraumatic administration of the fluid takes place after a predetermined fluid pressure has been reached.3. The system in accordance with claim 2 , wherein the infusion member is disposed so as to be axially displaceable in the first lumen of the aspiration catheter.4. The system in accordance with claim 3 , wherein the openings have a diameter between 20 μm and 50 μm.5. The system in accordance with claim 4 , wherein the balloon has a plurality of openings with an average density per unit area of at least 1000 openings per cm.6. The system in accordance with claim 5 , wherein the balloon has at least 1000 openings.7. The system in accordance with claim 1 , wherein ...

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Номер записи: 76
09-04-2020 дата публикации

Systems and Methods for Treating Vascular Occlusions with Catheter Based Ultrasound

Номер: US20200107843A1
Автор: Goertz David, HYNYNEN Kullervo, Wright Alex
Принадлежит:

A system and method is provided for generating ultrasound at the tip of an intravascular catheter. This may be used for the treatment of vascular occlusions, including chronic total occlusions (CTOs) and thrombotic occlusions (e.g., deep vein thrombosis, stroke, myocardial infarction). For instance, the systems and methods may be used to induce cavitation to enhance the enzymatic degradation of a vascular occlusion. In some configurations, the approach employs a hollow cylindrical transducer, electrically stimulated in the radial direction at a frequency corresponding to the length mode excitation, thereby projecting ultrasound forwards past the catheter tip. This design overcomes electrical impedance issues for the generation of low frequencies with a smaller diameter transducer capable of negotiating a coronary artery. The hole within the transducer may accommodate a guidewire to facilitate its placement adjacent to the proximal portion of the occlusion. 1. A system for delivering a treatment to a vascular occlusion comprising:a catheter extending from a proximal end to a distal end along a longitudinal axis and having a lumen extending therethrough;an ultrasound transducer coupled to the distal end of the catheter and coaxial with the longitudinal axis of the catheter, the ultrasound transducer comprising a cylindrical annular transducer having a lumen extending therethrough; andwherein the ultrasound transducer is configured to generate ultrasound in a forward facing direction extending outward from the distal end of the catheter.2. The system of claim 1 , wherein the ultrasound transducer is configured to generate ultrasound using stimulation such that inward propagating ultrasound energy is generated in the lumen of the ultrasound transducer claim 1 , and outward propagating ultrasound energy is generated in the forward facing direction extending outward from the distal end of the catheter.3. The system of claim 1 , wherein the lumen of the catheter and the ...

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Номер записи: 77
09-04-2020 дата публикации

Intravascular Ultrasound Device and Methods for Avoiding or Treating Reperfusion Injury

Номер: US20200107844A1
Автор: Goldstein Bryan H., Haworth Kevin, Holland Christy K., Mercado-Shekhar Karla, Redington Andrew
Принадлежит:

Intravascular ultrasound (IVUS) catheter-based device for targeted delivery of ultrasound-activated emulsions of oxygen-scavenging droplets into the bloodstream of patients suffering from a hypoxic condition and methods utilizing the device to protect the patient from reperfusion injury upon restoration of oxygenated blood to the hypoxic tissue. 1. A method for protecting a patient suffering from a hypoxic condition against reperfusion injury , the method comprising: delivering an emulsion into a blood vessel of a patient via a catheter-based system; and activating the emulsion prior to or subsequent to delivery by application of intra-vascular ultrasound , such that the activated emulsion scavenges dissolved oxygen present in blood flowing in the blood vessel.2. The method according to claim 1 , wherein the emulsion comprises droplets comprising a core claim 1 , said core comprising perfluorohexane claim 1 , perfluoropentane claim 1 , perfluoropropane claim 1 , perfluorobutane claim 1 , or combinations thereof.3. The method according to claim 1 , wherein the hypoxic condition is selected from a) coronary ischemic occlusion; b) myocardial infarction; c) cerebral ischemic occlusion; d) ischemic stroke; e) peripheral arterial disease; f) transplant procedure; g) crush injury; h) deep vein thrombosis; i) pulmonary embolism; and h) a medical procedure that required temporary partial or complete hemostasis.4. The method according to claim 1 , wherein the ultrasound activation is performed by one or more transducers located on a catheter.5. The method according to claim 4 , wherein one or more transducers comprise an opening through which the emulsion flows.6. The method according to claim 4 , wherein the emulsion flows around the one or more transducers.7. The method according to claim 1 , wherein the activation ultrasound comprises frequencies between 500 kHz and 60 MHz.8. The method according to claim 1 , wherein the activation ultrasound varies from one-half cycle to ...

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Номер записи: 78
03-05-2018 дата публикации

Abrading Balloon Catheter for Extravasated Drug Delivery

Номер: US20180117292A1
Автор: Gerrans Lawrence J., Gunday Erhan H.
Принадлежит:

A method of extravasated drug delivery is disclosed, including inserting a catheter with a first balloon, a second balloon, and a third balloon positioned between the first and second balloons and having a wall with an abrasive outer surface, into a bodily cavity, inflating the first and second balloons to create a chamber therebetween, stimulating a flow of blood cells by inflating the third balloon until the abrasive outer surface abrades tissue, and delivering the agent to the chamber. A balloon catheter system is also provided including a balloon having a wall with an abrasive outer surface for abrading tissue, a catheter having a first lumen for supplying fluid to the balloon to inflate the balloon such that the abrasive surface stimulates a flow of blood cells, and a second lumen for supplying an agent to tissue. 1 a first balloon;', 'a second balloon; and', 'a third balloon positioned between the first and second balloons and having a wall with an abrasive outer surface;, 'inserting a catheter into a bodily cavity, said catheter comprising'}inflating the first and second balloons to create a chamber between the first balloon and the second balloon, wherein the boundaries of the chamber are defined by an inner surface of the cavity wall and the catheter;stimulating a flow of blood cells by repeatedly inflating and deflating the third balloon by supplying fluid to the third balloon such that the abrasive outer surface abrades tissue in the bodily cavity as the third balloon is repeatedly inflated and deflated; anddelivering the therapeutic and/or diagnostic agent to the chamber and external of the third balloon after stimulating the flow of blood cells.. A method of extravasated delivery of a therapeutic and/or diagnostic agent to tissue, comprising the steps of: The present invention relates to methods and systems for delivering therapeutic and diagnostic agents to specific cellular locations within and adjacent to bodily tissues and cavities. More ...

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Номер записи: 79
25-08-2022 дата публикации

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF THROMBOSIS AND DELIVERY BY MEDICAL DEVICES

Номер: US20220265291A9
Автор: Handley Michael K.
Принадлежит: Marizyme, Inc.

A pharmaceutical composition and a method of using the pharmaceutical composition for the treatment of thrombosis are provided. The pharmaceutical composition can include a mixture of proteolytic enzymes, and optionally, additional compounds. The pharmaceutical composition can include an antiaggregatory or anti-thrombotic compound, such as Lisini racemici acetylsalicylase. The method can include administering the pharmaceutical composition to a patient in need thereof, including administration of the pharmaceutical composition to a thrombus until the thrombus is dissolved. The method can also include administering one or more balloon catheters to the patient. 1. A method for treating thrombosis in a patient in need thereof , comprising:administering a pharmaceutical composition comprising a proteolytic enzyme or mixture of proteolytic enzymes to the patient, andadministering a first balloon catheter to the patient.2. The method according to claim 1 , wherein the first balloon catheter comprises a balloon claim 1 , a first tube claim 1 , and a second tube claim 1 , the first and second tubes each having an inlet located at the same side of the balloon claim 1 ,wherein the first tube has an outlet inside of the balloon to inflate the balloon, and the second tube has an outlet located on another end of the balloon distant from the inlet to be located between the balloon and the thrombus.3. The method according to claim 1 , further comprising administering a second balloon catheter to the patient.4. The method according to claim 1 , wherein the pharmaceutical composition further comprises Lisini racemici acetylsalicylase.5. The method according to claim 4 , wherein the mixture of proteolytic enzymes comprises Krill enzymes.6. A method of treating thrombosis in a patient claim 4 , comprising:a) blocking a vessel containing a thrombus downstream of said thrombus with a first balloon catheter to form a small volume between the first balloon catheter and the thrombus,b) ...

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Номер записи: 80
25-04-2019 дата публикации

Diagnostic Method, Method for Validation of Diagnostic Method, and Treatment Method

Номер: US20190117181A1
Автор: Fukuoka Tetsuya, ISHII Shota, ITOU Yoshitaka, Saito Yoshiyuki
Принадлежит: TERUMO KABUSHIKI KAISHA

A method is disclosed for diagnosing and treating a patient having lesions in both arteries of left and right lower limbs. By determining that a higher stenosis rate lesion to be treated first, catheters and an operation time can be reduced is to be treated first on a priority basis based on diagnostic data, deciding that a lower stenosis rate lesion is to be treated next, then treating the lesions substantially continuously. 1. A method for diagnosing lesions in a plurality of bifurcated lumens , the plurality of bifurcated lumens being connected to a biological lumen via a bifurcation from a main lumen , the method comprising:detecting electromagnetic waves obtained through a patient by irradiating the patient with electromagnetic waves, and obtaining electromagnetic wave information on the patient based on a changed electromagnetic wave;identifying a plurality of lesions from the electromagnetic wave information;acquiring the stenosis rate information on the plurality of lesions; anddetermining a lesion to be treated first among the plurality of lesions based on the stenosis rate information.2. The diagnostic method according to claim 1 , wherein when there is one lesion present in each of the plurality of bifurcated lumens claim 1 , the method comprising:determining the lesion to be treated first to be a higher stenosis rate lesion based on the stenosis rate information.3. The diagnostic method according to claim 1 , wherein in a case where the main lumen is an aorta claim 1 , the bifurcation is an aortailiac bifurcation claim 1 , and the plurality of bifurcated lumens are left and right lower limb arteries claim 1 , and the left and right lower limb arteries each have lesions claim 1 , the method comprising:obtaining the stenosis rate information from the bifurcation for each of the lesions; anddetermining a higher stenosis rate lesion of the plurality of lesions is to be treated first based on the stenosis rate information.4. The diagnostic method according to ...

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Номер записи: 81
16-04-2020 дата публикации

Ultrasound Catheter Having Improved Distal End

Номер: US20200114119A1
Автор: Nita Henry
Принадлежит:

A method of making an ultrasonic catheter, disposing an ultrasound member in the main lumen of a flexible catheter body; providing an intermediate member and a tip, wherein at least a tip maximum-diameter portion is disposed in the intermediate member, wherein an intermediate-member outer diameter substantially matches a main lumen inner diameter, and wherein a tip distal cross-section has a tip distal cross-section area less than a tip proximal cross-section area of a tip proximal cross-section; and attaching the intermediate member to the catheter body and to the tip, wherein at least one of the tip and the intermediate member is configured to prevent separation of the tip of the ultrasound member from the catheter body. 120-. (canceled)21. A method of making an ultrasonic catheter , comprising:providing a flexible catheter body having a main lumen;disposing an ultrasound member in the main lumen, the ultrasound member having a proximal end that is configured to connect to a generating device;providing an intermediate member and a tip, wherein at least a tip maximum-diameter portion is disposed in the intermediate member, wherein a tip distal cross-section defines a first region and a tip proximal cross-section defines a second region and a transition is disposed between the first region and the second region, and having an additional region with a shape selected from one or more of flat, round, tapered, and concave, wherein an intermediate-member outer diameter substantially matches a main lumen inner diameter, and wherein the tip distal cross-section has a tip distal cross-section area less than a tip proximal cross-section area of the tip proximal cross-section; andattaching the intermediate member to the catheter body and to the tip, wherein at least one of the tip and the intermediate member is configured to prevent separation of the tip of the ultrasound member from the catheter body.22. The method of claim 21 , comprising disposing a cap on the tip.23. The ...

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Номер записи: 82
27-05-2021 дата публикации

Actuated expandable mouth thrombectomy catheter

Номер: US20210153884A1
Автор: Brendan Casey, David Vale, Karl Keating, Ronald Kelly
Принадлежит: Neuravi Ltd

A clot retrieval catheter can have an expansile distal tip for flow restriction/arrest and improved aspiration efficiency and a large, distal facing mouth into which clots or other obstructions can be retrieved. The tip can be formed from a distal ring of leaflets or hoops. One or more pull cables can be retracted to actuate and radially expand the expansile distal tip. The clot retrieval catheter can have a catheter shaft with flexibility-adding features proximal of the tip. The catheter shaft can be a multi-lumen configuration with a large catheter lumen for passing auxiliary devices and directing aspiration and one or more guide lumens which can route the pull cables to the leaflets or hoops of the expansile tip. A flexible, low-modulus membrane can be disposed around at least a portion of the expansile tip and catheter shaft.

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Номер записи: 83
10-05-2018 дата публикации

AXIAL LENGTHENING THROMBUS CAPTURE SYSTEM

Номер: US20180125512A1
Автор: Ngo Tung Hoang, Nguyen Duy, Nguyen Thanh Van
Принадлежит:

Disclosed herein are systems and methods to remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions. 120-. (canceled)21. A method of retrieving a thrombus , comprising:accessing an interior of a blood vessel;advancing a shape memory body through the blood vessel, wherein the shape memory body comprises a first end, a second end, and an axial length therebetween;expanding the first end distal to the thrombus while the second end and a majority of the shape memory body remains compressed, wherein the second end is positioned proximal to the first end, wherein the shape memory body comprises a first expanded axial length; andadjusting the shape memory body wherein the shape memory body has a second expanded axial length greater than the first expanded axial length to capture a thrombus.22. The method of claim 21 , further comprising isolating the thrombus within the shape memory body.23. The method of claim 21 , wherein a first width along the first expanded axial length and a second width of the shape memory body along the second expanded axial length are substantially the same.24. The method of claim 21 , wherein a distal end of the shape memory body is distal to the first end when the first end is expanded.25. The method of claim 21 , further comprising suctioning claim 21 , macerating claim 21 , and/or mechanically removing the thrombus.26. The method of claim 21 , further comprising positioning an expanding guiding catheter proximal to the thrombus.27. The method of claim 26 , further comprising retracting the shape memory body with the thrombus into a funnel tip of expanding guiding catheter.28. The method of claim 21 , further comprising axially lengthening the shape memory body distally after adjusting the shape memory body.29. The method of claim 21 , further ...

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Номер записи: 84
01-09-2022 дата публикации

Catheter Systems Enabling Improved Aspiration from Cerebral Arteries

Номер: US20220273322A1
Автор: GOYAL Mayank
Принадлежит: MG Stroke Analytics Inc.

A distal entry point (DEP) to brain aspiration (D2BA) catheter for use in an endovascular procedure for gaining access to cervical and cerebral arteries in a brain of a patient and aspirating one or more intracranial clots from the cerebral arteries, comprising a soft distal tip region having a distal length sufficient to extend from a level 1 or level 2 arterial segment of a cerebral artery or equivalent to an upper neck arterial vessel, a stiffness enabling movement through the level 1 or level 2 arterial segment of the cerebral artery, and an outside diameter (OD) of 6F-10F, a proximal region having a stiffness greater than the stiffness of the soft distal tip region, the proximal region having a length sufficient to extend to outside the patient through the DEP. 160-. (canceled)61. A catheter for gaining access to cervical and cerebral arteries in a brain of a patient and for aspirating intracranial clots from the cerebral arteries , comprising:a catheter body having a distal tip section and proximal section, the catheter body having:a catheter body length of greater than 120 cm;a distal tip section length of 12-30 cm; and,a outside diameter (OD) greater than 6F and less than 10F.62. The catheter as in where the distal tip section has a stiffness enabling the distal tip section to ride over a guide wire (GW) and diagnostic catheter (DC) positioned beyond the aortic arch through the aortic arch without external support.63. The catheter as in where the stiffness of the distal tip section is less than a proximal section stiffness.64. The catheter as in where the outside diameter (OD) is 7F and the distal tip section length corresponds to a distance from an upper neck arterial vessel to level 2 segments of the middle cerebral artery or from the distal cervical vertebral artery to the basilar artery or equivalent.65. The catheter as in where the distal tip section length is 17-25 cm.66. The catheter as in where the OD is greater than 8F and the distal tip section ...

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Номер записи: 85
23-04-2020 дата публикации

REMOVAL TOOL FOR USE WITH ENDOSCOPIC DEVICE

Номер: US20200121340A1
Автор: Dusabek Andrew Joseph, Olson Scott Arvin, Raijman Isaac, Springs Christen Andrew
Принадлежит: CONMED CORPORATION

A system for use with an endoscopic device. The system can include a shaft having a proximal end, a distal end, and at least one output port, wherein a portion of the shaft is surrounded by a single polyurethane expandable material, wherein the polyurethane expandable material is expandable from a diameter of at least approximately 5.0 mm to a diameter of approximately 25 mm. The system can also include a manifold connected to the proximal end of the shaft, the manifold including one or more fluid coupling ports for receiving an injected fluid, wherein at least one of the one or more fluid coupling ports is in fluid communication with the at least one output port and wherein when received, the system is configured to convey the injected fluid from the manifold to the shaft resulting, at least in part, in expanding the polyurethane expandable material. 1. A system for use with an endoscopic device , comprising:a shaft having a proximal end, a distal end, and at least one output port, wherein a portion of the shaft is surrounded by a single polyurethane expandable material, wherein the polyurethane expandable material is expandable from a diameter of at least approximately 5.0 mm to a diameter of approximately 25 mm; anda manifold connected to the proximal end of the shaft, the manifold comprising one or more fluid coupling ports for receiving an injected fluid, wherein at least one of the one or more fluid coupling ports is in fluid communication with the at least one output port and wherein when received, the system is configured to convey the injected fluid from the manifold to the shaft resulting, at least in part, in expanding the polyurethane expandable material.2. The system of claim 1 , wherein each of the one or more fluid coupling ports is in fluid communication with only one of the at least one output port.3. The system of claim 1 , wherein the shaft comprises a plurality of output ports comprising a distal output port claim 1 , medial output port claim 1 , ...

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Номер записи: 86
23-04-2020 дата публикации

Stent Retriever Having an Expandable Fragment Guard

Номер: US20200121355A1
Автор: Eskridge Joe Michael
Принадлежит:

A stent retriever assembly having a proximal end and a distal end and including a mesh tube having a distal and proximal end and being connected to a first wire. Also, a blood-porous fragment guard is at the distal end of the mesh tube and has a central hub and extending radially and proximally from the central hub. Further, a second wire is connected to the central hub, and when this second wire is pulled proximally relative to the first wire, the hub is pulled proximally, which thereby causes the fragment guard to deploy in expanded form. 1. A stent retriever assembly having a proximal end and a distal end , and comprising:(a) a mesh tube having a distal and proximal end, and being connected to a first wire; and(b) a blood-porous fragment guard at said distal end of said mesh tube, said fragment guard including a central hub and extending radially and proximally from said central hub, and wherein a second wire is connected to said central hub, and wherein when said second wire is pulled proximally relative to said first wire, said hub is pulled proximally, which thereby causes said fragment guard to deploy in expanded form.2. The stent retriever assembly of claim 1 , wherein said mesh tube is made claim 1 , at least in part claim 1 , of a metal mesh that is stiff claim 1 , so that when said second wire is pulled proximally claim 1 , said metal mesh resists being pulled proximally claim 1 , due to said stiffness.3. The stent retriever assembly of claim 1 , wherein said fragment guard includes spokes claim 1 , and wherein when said second wire is pulled proximally relative to said first wire claim 1 , the hub moves proximally and causes said spokes to spread out claim 1 , which thereby causes said fragment guard to deploy in expanded form.4. The stent retriever assembly of claim 3 , wherein said fragment guard claim 3 , in addition to said spokes claim 3 , includes threads extending across and between said spokes claim 3 , to create a finer mesh claim 3 , better ...

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Номер записи: 87
03-06-2021 дата публикации

System and method for treatment of eustachian tube from middle ear approach

Номер: US20210161719A1
Автор: Andy Nguyen, Dennis S. Poe, Holger Sudhoff, Hung V. Ha, Ketan P. Muni, Marc DEAN, Randy S. Chan, Sivette Lam
Принадлежит: Acclarent Inc

A dilation catheter includes a shaft and an expandable element. The shaft includes a proximal portion and a distal portion. The distal portion includes a tip and a bend. The tip is sized and configured to pass through an isthmus of a Eustachian tube (ET). The bend is proximal to the tip. The bend is formed at an angle configured to provide insertion of the tip into the isthmus of the ET via an ear canal associated with the ET. The expandable element is disposed at the distal portion of the shaft. The expandable element is configured to transition between a non-expanded state and an expanded state. The expandable element in the non-expanded state is configured for insertion into the ET via the isthmus. The expandable element in the expanded state is configured to dilate the ET.

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Номер записи: 88
19-05-2016 дата публикации

FLUID SUPPLY AND SUCTION DEVICE

Номер: US20160135826A1
Автор: Chadbourne David Michael
Принадлежит:

A fluid supply and suction device is provided and includes a tube, a container including first and second parts, which are sealably attachable to define a container interior, the first part being formed to define first and second apertures and being coupled with the tube such that the tube is fluidly communicative with the container interior and a valve system coupled with the first part and configured to admit via the first aperture fluid into the tube such that the fluid flows through the tube and to suction via the second aperture fluid and fragmented particles through the tube and into the container interior. 1. A fluid supply and suction device , comprising:a tube;a container including first and second parts, which are sealably attachable to define a container interior, the first part being formed to define first and second apertures and being coupled with the tube such that the tube is fluidly communicative with the container interior; anda valve system coupled with the first part and configured to admit via the first aperture fluid into the tube such that the fluid flows through the tube and to suction via the second aperture fluid and fragmented particles through the tube and into the container interior.2. The fluid supply and suction device according to claim 1 , wherein the first part comprises a body formed to define:a receiving chamber sized to tightly fit around the tube; andan inlet chamber coupled with the valve system, the inlet chamber being adjacent to the receiving chamber and proximate to the first aperture,wherein an outer diameter of the inlet chamber is similar to an inner diameter of the tube.3. The fluid supply and suction device according to claim 1 , wherein the first and second parts are threadably engageable with each other.4. The fluid supply and suction device according to claim 1 , wherein the first and second parts are attachable to each other via mechanical or frictional interference.5. The fluid supply and suction device according ...

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Номер записи: 89
17-05-2018 дата публикации

Embolic protection system including multiple filter bodies

Номер: US20180132873A1
Автор: Sengkham Sirivong
Принадлежит: COVIDIEN LP

In some examples, an embolic protection system includes an elongated member, a first filter body mechanically connected to the elongated member and defining a first filter mouth and a first filter end, the first filter mouth being one of proximal or distal to the first filter end, and a second filter body mechanically connected to the elongated member and distal to the first filter body, the second filter body defining a second filter mouth and a second filter end, the second filter mouth being the one of proximal or distal to the second filter end. In some instances, at least a section of the elongated member between the first and second filter bodies may be flexible, and may be configured to conform to a shape of an arch between two vessels of a patient.

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Номер записи: 90
18-05-2017 дата публикации

Transcarotid Neurovascular Catheter

Номер: US20170136212A1
Автор: Garrison Michi E., Wilson Scott D.
Принадлежит:

An interventional catheter for treating an artery includes an elongated body sized and shaped to be transcervically introduced into a common carotid artery at an access location in the neck. The elongated body has an overall length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use. 119-. (canceled)20. A method of treating an artery , comprising:introducing an interventional catheter formed of elongated body into a common carotid artery via an access location in a neck, the elongated body sized and shaped to be introduced into the common carotid artery at the access location in the neck, wherein the elongated body includes an internal lumen forming a proximal opening in a proximal region of the elongated body and a distal opening in a distal region of the elongated body, and wherein the elongated body has a proximal most section and a distal most section wherein the proximal most section is a stiffest portion of the elongated body and wherein the elongated body has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and while simultaneously at least a portion of the proximal most section is positioned in the common carotid artery during use;:(a) wherein the distal most section of the catheter has an inner diameter of 0.068 to 0.095 inch;(b) wherein the catheter can navigate around a 180° bend with a radius of 0.100″ without kinking;(c) wherein the catheter does not collapse when connected to a vacuum up to 25 inHg while navigating around a 180° bend with a radius of 0.100″;navigating the elongated body distally to an intracranial artery through the common carotid artery.21. A method as in claim 20 , wherein the elongated body includes a first transition section between the proximal section and the distal most section claim 20 , and wherein the transition ...

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Номер записи: 91
09-05-2019 дата публикации

THROMBECTOMY DEVICE AND METHODS OF USE

Номер: US20190133616A1
Автор: Ha Hung, Sachar Ravish, SERINA Eugene, Stern Dave
Принадлежит:

The device disclosed herein is used to the remove a thrombus from the vasculature. It includes an aspiration catheter and a thrombus retrieval device that extends through the lumen of the aspiration catheter. An expandable braided assembly extends over a distal region of the retrieval device, and an activation wire extends through the lumen of the retrieval device to attach to and control the expansion of the braided assembly. Applying tension to the activation wire causes the braided assembly to expand to a diameter of the practitioner's choosing. For example, the practitioner may apply a first level of tension to the activation wire to deploy the braided assembly to a first diameter and then later change the diameter by applying a different level of tension. The expanded braided assembly contacts the thrombus and is pulled proximally toward the aspiration catheter to assist in thrombus removal. 1. A thrombectomy device comprising:an aspiration catheter comprising a proximal end and a distal end;a retrieval device configured to extend through the aspiration catheter and exit at the distal end, the retrieval device comprising a proximal region, a distal region, and a first lumen extending therebetween;at least one braided assembly extending over a distal region of the retrieval device, the braided assembly comprising at least one slidable collar, a braid attached to the slidable collar and extending toward a fixed attachment point that anchors the braid to the retrieval device;at least one activation wire extending through the first lumen of the retrieval device and through an exit point located on the distal region, wherein a distal end of the activation wire is attached to the slidable collar;wherein the braid has a shape memory of a collapsed configuration;wherein the braided assembly can be expanded to a range of expanded outer diameters by varying the level of tension on the activation wire.2. The thrombectomy device of claim 1 , wherein the exit point is a ...

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Номер записи: 92
09-05-2019 дата публикации

A device for ultrasonic-accelerated hematoma lysis or thrombolysis of intracerebral or intraventricular hemorrhages or hematomas

Номер: US20190133620A1
Автор: Giese Alf, Keric Nauren, Masomi-Bornwasser Julia
Принадлежит:

The present invention relates to a device for ultrasonic-accelerated hematoma lysis or thrombolysis of intracerebral or intraventricular hemorrhages or hematomas, comprising a body which accommodates a number of separated compartments or lumens consisting of a flushing catheter for flushing fluid and/or pharmaceutically active substances into the intracerebral or intraventricular hemorrhages or hematomas, a drainage catheter for draining fluid from the intracerebral or intraventricular hemorrhages or hematomas, an ultrasonic probe duct, and a pressure sensor duct, wherein the compartments or lumens are arranged in proximity to each other and wherein in longitudinal extension at least upper-part sections of the compartments or lumens are isolated by walls, wherein the lumen of the pressure sensor duct integrates a pressure sensor, and wherein in the lumen of ultrasonic probe duct an endosonographic probe or a stiletto is interchangeably guided. 211121220. The device according to claim 1 , wherein an upper proximal part portion (.) of the flushing catheter () and/or upper proximal part portion (.) of the drainage catheter () laterally projects from the body () in bended form.3222028. The device according to claim 1 , wherein in a lower distal part (.) of the body () claim 1 , an outer wall of the drainage catheter () comprises apertures ().4122220217. The device according to claim 1 , wherein in lower distal parts (. claim 1 , .) of the body () claim 1 , the drainage catheter () and the flushing catheter () are permeably connected by one or more penetrations ().532123. The device according to claim 1 , wherein the ultrasonic probe duct () is arranged oppositely to the drainage catheter () claim 1 , and wherein at least a section of the flushing catheter () is arranged between the drainage catheter () and the ultrasonic probe duct ().65620. The device according to claim 1 , wherein the pressure sensor duct () that integrates the pressure sensor () is arranged at an ...

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Номер записи: 93
15-09-2022 дата публикации

THROMBUS REMOVAL DEVICE

Номер: US20220287729A1
Автор: Dent Wanda F., Drilling Sarah E., Phillips Shawn, Twomey Alan M., Weidenhamer Nathan K., Willard Martin R.
Принадлежит:

In some examples, a thrombus removal device includes a stationary element and a movable element configured to macerate a thrombus into smaller pieces as the thrombus moves into a basket defined by an expandable element. The stationary element defines a plurality of arms configured to segment the thrombus into smaller pieces. The movable element is configured to move relative to the stationary element, e.g., to rotate, plunge, vibrate, and/or oscillate, in order to macerate the thrombus. 1. A medical device comprising:an elongated support member;an expandable element disposed on the elongated support member,a stationary element comprising a plurality of arms, wherein the plurality of arms is configured to segment a thrombus into smaller pieces as the thrombus moves through the stationary element, wherein the expandable element is configured to capture at least some of the smaller pieces; anda movable element disposed radially inward from the stationary element, the movable element configured to move relative to the stationary element to macerate the thrombus as the thrombus moves through the stationary element.2. The medical device of claim 1 , wherein the movable element is configured to expand radially outward from a delivery configuration to a deployed configuration claim 1 , and wherein the movable element is configured to move within a volume defined by the stationary element.36-. (canceled)7. The medical device of claim 1 , wherein the movable element comprises a rotatable element; and wherein the medical device further comprises a rotatable tube disposed around the support structure claim 1 , wherein the rotatable element is coupled to the rotatable tube and is configured to rotate about a longitudinal axis of the support structure to rotate the rotatable element relative to the stationary element.8. The medical device of claim 7 , wherein the rotatable element is configured to oscillate between a first rotational speed and a second rotational speed.9. The ...

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Номер записи: 94
07-05-2020 дата публикации

WIRE AND DEVICE FOR VASCULAR TREATMENT

Номер: US20200138475A1
Автор: Tal Michael G.
Принадлежит:

A wire for use with a vascular treatment device may have a proximal end, a distal end, and a main shaft extending therebetween. The distal end may have a distal free end and a first segment. The first segment may extend from the main shaft and may be biased to a first included angle that is defined between the main shaft and the first segment and less than 180 degrees. 152-. (canceled)53. A wire for use with a vascular treatment device , the wire comprising: a first portion that extends from the proximal end to a bend, and', 'a second portion that extends from the bend to the distal end, the second portion comprising a first segment;', 'wherein the first portion and the first segment are biased relative to each other at a first interior angle that is less than 180 degrees, and', 'wherein the distal end is axially offset from the proximal end., 'a shaft having a proximal end and a distal end, the shaft further comprising54. The wire of claim 54 , wherein the distal end of the wire is configured to rotate within the vascular treatment device.55. The wire of claim 54 , wherein the second portion further comprises:a second segment, wherein the first segment extends between the bend and the second segment, wherein the first segment and the second segment are biased relative to each other at a first interior angle that is less than 180 degrees.56. The wire of claim 55 , wherein the second portion further comprises:a third segment distal to the second segment, wherein the second segment and the third segment are biased relative to each other at a first interior angle that is less than 180 degrees.57. The wire of claim 53 , wherein the distal end of the wire terminates with a pointed free end.58. The wire of claim 53 , wherein the distal end of the wire terminates with a hemispheric free end.59. The wire of claim 53 , wherein the distal end of the wire terminates with a flat free end.60. The wire of claim 53 , wherein the distal end of the wire terminates with a ball-shaped ...

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Номер записи: 95
17-06-2021 дата публикации

Catheter with multiple ultrasound radiating members

Номер: US20210178140A1
Автор: Amy Cohen, Curtis Genstler, George Keilman, Leonard R. Oliver, Natalya Peskin, Richard R. Wilson, Robert L. Wilcox, Tim Abrahamson, Wm. Gerrit Barrere
Принадлежит: Ekos LLC

A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The ultrasonic catheter system comprises a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end, a fluid delivery lumen, at least one ultrasound radiating element positioned in the treatment zone, wiring electrically coupled to the at least one ultrasound radiating element and extending through the tubular body and terminating at a connector, and a control system comprising external circuitry and an isolation pod that is configured to be electrically connected to the connector, the isolation pod being positioned between the tubular body and the external system and comprising an isolation barrier and circuitry for driving the ultrasound radiating element.

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Номер записи: 96
07-06-2018 дата публикации

DISRUPTIVE DRESSING FOR USE WITH NEGATIVE PRESSURE AND FLUID INSTILLATION

Номер: US20180153570A1
Автор: Arnold Peter, Carroll Christopher A., Ingram Shannon C., Locke Christopher Brian, Manwaring Michael E., Robinson Timothy Mark
Принадлежит:

A method and apparatus for disrupting material at a tissue site is described. A contact layer may be selected for use on the tissue site and positioned adjacent to the tissue site. The contact layer may include walls defining a plurality of through-holes. A sealing member may be positioned over the contact layer and sealed to tissue surrounding the tissue site to form a sealed space enclosing the contact layer. A negative-pressure source may be fluidly coupled to the sealed space. The negative-pressure source may supply negative pressure to the sealed space and the contact layer to draw tissue into the through-holes to form nodules. The negative pressure may be vented from the sealed space to release the nodules. 143.-. (canceled)44. A system for softening materials at a tissue site , comprising:a contact layer formed from a compressible material and configured to be positioned adjacent the tissue site, the contact layer comprising a plurality of through-holes;a cover adapted to form a sealed space over the contact layer and the tissue site for receiving a negative pressure from a negative-pressure source; andwherein the through-holes are configured to receive tissue in the through-holes in response to negative pressure in the sealed space to form nodules in the tissue site.45. The system of claim 44 , further comprising a fluid source adapted to be fluidly coupled to the sealed space to provide fluid to the sealed space.4648.-. (canceled)49. The system of claim 44 , wherein the plurality of through-holes are formed in an array.50. The system of claim 49 , wherein the array comprises two or more parallel rows.51. (canceled)52. (canceled)53. The system of claim 44 , wherein a firmness factor of the contact layer is between about 1 and about 10.54. (canceled)55. (canceled)56. The system of claim 44 , wherein a shape of each through-hole of the plurality of through-holes is selected from a group consisting of hexagonal claim 44 , elliptical claim 44 , circular claim 44 ...

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Номер записи: 97
24-06-2021 дата публикации

ASPIRATION CATHETER AND PUMP SYSTEM FOR TREATING ISCHEMIC STROKE

Номер: US20210186534A1
Автор: Couri Duane, Espinosa Alejandro, FARNAN Robert, Hunt Timothy Brandon
Принадлежит: POSEYDON MEDICAL, LLC

The present invention relates to methods and systems for performing the removal of thrombus from a vessel lumen. More particularly the present invention relates to a thrombectomy system that includes an elongate catheter and a disposable aspiration pump and methods of performing medical procedures to remove clots, thrombus and emboli to re-establish the normal intravascular flow of blood. 1. A thrombus removal system for use in the neurovasculature comprising:an elongate tubular catheter having proximal and distal segments, a wall, an inner diameter, an outer diameter, proximal and distal ends and a lumen extending there between, said catheter distal segment having reinforcement to provide kink resistance such that when outer diameter has a bend radius of at least two times the inner diameter the catheter does not kink and said catheter distal segment having a sufficient radial resistance such that the catheter distal segment does not collapse when subjected to a negative pressure; andan aspiration pump having a pump assembly including a length tubing having a connector end, a controller, an aspiration container, a housing, a user interface, and an operable mode, said connector end being adapted to couple to the proximal end of said catheter wherein when said aspiration pump is coupled to said catheter positioned within the vasculature and operated, said pump can controllably cycle between supplying negative and positive pressure to said catheter to aspirate a thrombus through the catheter to the pump aspiration container.2. A thrombus removal system as in wherein said catheter has an inner diameter greater than 0.085 inches.3. A thrombus removal system as in wherein said catheter wall has a thickness and the ratio of the inner diameter to the diametric wall thickness is greater than 4.4. A thrombus removal system as in wherein said positive pressure does propel aspirated material within the catheter distal to the catheter distal end.5. A thrombus removal system as ...

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Номер записи: 98
24-06-2021 дата публикации

Methods and systems for advancing a catheter to a target site

Номер: US20210186536A1
Автор: James Jacobs, Julia Fox, Michael Buck
Принадлежит: Imperative Care Inc

A catheter has a cannulated guiding rail extending therethrough, an advance segment of the rail extending at least about 10 cm beyond the distal end of the catheter. The catheter and rail are advanced over a guidewire until the distal end of the advance segment is at a target vascular site. The catheter is thereafter advanced along the rail to the target vascular site.

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Номер записи: 99
24-06-2021 дата публикации

Methods and systems for treating a pulmonary embolism

Номер: US20210187244A1
Автор: James Jacobs, Julia Fox, Michael Buck
Принадлежит: Imperative Care Inc

A large bore catheter has a guiding rail extending therethrough and an advance segment of the rail extends at least about 10 cm beyond the distal end of the catheter. The advance segment is advanced from the vena cava through the tricuspid and pulmonary valves of the heart into the central pulmonary artery while the distal end of the large bore catheter remains in the vena cava. The large bore catheter is thereafter distally advanced over the rail until the large bore catheter distal end is at least as far as the central pulmonary artery. The rail is thereafter proximally removed from the large bore catheter, and at least a portion of a clot is drawn from a pulmonary artery into the large bore catheter.

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Номер записи: 100