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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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12-01-2012 дата публикации

Energy based devices and methods for treatment of patent foramen ovale

Номер: US20120010608A1

Автор: Dan Francis, Hanson S. Gifford, Iii, Jose Alejandro, Kenneth Horne, Mark E. Deem, William Malecki

Принадлежит: Terumo Corp

Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device fuirther include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

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Номер записи: 1

10-05-2012 дата публикации

In-plane dual loop fixed diameter electrophysiology catheters and methods of manufacturing therefor

Номер: US20120116199A1

Автор: Alan de la Rama, Jennifer Velasco, Kailing Chen

Принадлежит: de la Rama Alan, Jennifer Velasco, Kailing Chen

An EP catheter includes a tubular body having a proximal region, a neck region, and a distal portion predisposed into an in-plane dual loop (at least, approximately, more or less) configuration and including a plurality of diagnostic electrodes. In deflectable catheter forms, at least one activation wire extends through at least a portion of the proximal region of the catheter body and is adapted to deflect the distal portion up to approximately 180 degrees relative to the proximal region. The catheter can be operated manually by a clinician or via a clinician-surrogate such as a computer processor-controlled surgical system. In addition, a variety of localization, visualization, and/or orientation-specific elements can be incorporated into the devices described, depicted, and claimed herein (e.g., metallic coil members, active impedance emitting or receiving electrodes, fluoroscopically opaque materials, and the like).

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Номер записи: 2

10-05-2012 дата публикации

Fixed loop deflectable electrophysiology catheters having an extended braid primary shaft coupled to the periphery of the fixed loop and methods of manufacturing therefor

Номер: US20120116200A1

Автор: Alan de la Rama, Jennifer Velasco, Pianka Roy

Принадлежит: de la Rama Alan, Jennifer Velasco, Pianka Roy

An EP catheter includes a tubular body having a proximal region, a neck region, and a distal portion predisposed into a single shallow helical fixed-diameter loop configuration and including a plurality of diagnostic electrodes. In deflectable catheter forms, at least one activation wire extends through at least a portion of the proximal region of the catheter body and is adapted to deflect the up to approximately 180 degrees relative to the proximal region. The catheter can be operated manually by a clinician or via a clinician-surrogate such as a computer processor-controlled surgical system. In addition, a variety of localization, visualization, and/or orientation-specific elements can be incorporated into the devices described, depicted, and claimed herein (e.g., metallic coil members, active impedance emitting or receiving electrodes, fluoroscopically opaque materials, and the like).

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Номер записи: 3

10-05-2012 дата публикации

Catheter with liquid-cooled control handle

Номер: US20120116393A1

Автор: Ariel Garcia, Arnold Tuason, Assaf Govari, Christopher Beeckler, Dean Ponzi, Eduardo Jimenez, Jeffrey W. Schultz, Mario Solis, Rogelio Plascencia, JR., Yaron Ephrath

Принадлежит: Biosense Webster Inc

An electrophysiologic catheter with an improved control handle is provided. The catheter includes a heat transfer assembly to better dissipate heat in the control handle. The heat transfer assembly includes a pump, a reservoir containing a coolant, a heat transfer member, and a coolant transport network transporting coolant between at least the reservoir and the heat transfer member. In one embodiment, the heat transfer member is located within the control handle as a heat exchanger on the circuit board to receive the coolant for transferring heat from the integrated circuits to the coolant. In another embodiment, the heat transfer member is located on the circuit board directly surrounding the integrated circuits to internally cool the integrated circuit within the control handle. A second heat transfer member is located outside of the control handle as a heat exchanger.

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Номер записи: 4

24-05-2012 дата публикации

Method and apparatus for performing transesophageal cardiovascular procedures

Номер: US20120130169A1

Автор: Sameh Mesallum

Принадлежит: Microaccess Inc

An apparatus for performing a transesophageal cardiovascular procedure includes an elongated tubular main access device having a first lumen with an open proximal end and a distal side opening, and a second lumen with a rigid outer wall and a collapsible inner wall. The second lumen is adapted to receive an elongated probe or surgical device. The apparatus further includes an inflatable sealing means on the outside of the main access device above and below the side opening, and a first fluid conduit extending along the main access device for inflating the sealing means so that when the main access device is inserted into a patient's esophagus and the sealing means are inflated. The portion of the esophagus opposite the side opening is isolated from the remainder of the esophagus above and below the side opening.

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Номер записи: 5

21-06-2012 дата публикации

System for controlling tissue ablation using temperature sensors

Номер: US20120157890A1

Автор: Andres Claudio Altmann, Assaf Govari, Yaron Ephrath

Принадлежит: Biosense Webster Israel Ltd

Body tissue ablation is carried out by inserting a probe into a body of a living subject, urging the probe into contact with a tissue in the body, generating energy at a power output level, and transmitting the generated energy into the tissue via the probe. While transmitting the generated energy the ablation is further carried out by determining a measured temperature of the tissue and a measured power level of the transmitted energy, and controlling the power output level responsively to a function of the measured temperature and the measured power level. Related apparatus for carrying out the ablation is also described.

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Номер записи: 6

26-07-2012 дата публикации

Apparatus and Methods for Determining a Subject's Response to Catheter-Based Ablation Therapy Based on Spectral Mapping During Sinus Rhythm

Номер: US20120191087A1

Автор: Enrique Indalecio Pachón Mateos, José Carlos Pachón Mateos

Принадлежит: St Jude Medical Atrial Fibrillation Division Inc

Apparatus for curative ablation are provided to achieve the inactivation or destruction of fibrillar myocardium of the so-called AF nests. In addition, fibrillar myocardium may be identified and mapped by spectral analysis and phase study of the tissue during sinus rhythm. The procedure may be performed by transseptal puncture using only one catheter for ablation and mapping. The methods may be used to localize the application targets even during an arrhythmia.

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Номер записи: 7

13-09-2012 дата публикации

Radiofrequency Perforation Apparatus

Номер: US20120232546A1

Автор: Gareth Davies, Mahmood Mirza

Принадлежит: Baylis Medical Co Inc

A radiofrequency perforation apparatus for creating a channel at a target location in a body of a patient, the radiofrequency perforation apparatus comprising: a substantially tubular member defining a tubular member lumen; an end member partially positioned within the tubular member lumen at a distal end of the tubular member, the end member including an electrode; and an electrical insulator extending along the substantially tubular member.

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Номер записи: 8

11-10-2012 дата публикации

Apparatus and methods to create and maintain an intra-atrial pressure relief opening

Номер: US20120259263A1

Автор: David Celermajer, Edward McNamara, Hiroatsu Sugimoto, Michael W. Sutherland

Принадлежит: DC Devices Inc

The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.

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Номер записи: 9

25-10-2012 дата публикации

Methods for detection of cardiac rhythm disorders using basket style cardiac mapping catheter

Номер: US20120271136A1

Автор: Ruchir Sehra, Thomas F. Kordis

Принадлежит: Topera Inc

A method for sensing multiple local electric voltages from endocardial surface of a heart, includes: providing a system for sensing multiple local electric voltages from endocardial surface of a heart, including: a first elongate tubular member having a lumen, a proximal end and a distal end; a basket assembly including: a plurality of flexible splines for guiding a plurality of exposed electrodes, the splines having proximal portions, distal portions and medial portions therein between, wherein the electrodes are substantially flat electrodes and are substantially unidirectionally oriented towards a direction outside of the basket.

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Номер записи: 10

25-10-2012 дата публикации

Apparatus and Method for Ablating Tissue

Номер: US20120271334A1

Автор: Benjamin Pless, David A. Gallup, Jack E. Ulstad, Jr., John E. Crowe, Jonathan L. Podmore, Matthias Vaska, Roxanne L. Richman, Scott C. Anderson, Timothy Ciciarelli

Принадлежит: Individual

A control system alters one or more characteristics of an ablating element to ablate tissue. In one aspect, the control system delivers energy nearer to the surface of the tissue by changing the frequency or power. In another aspect, the ablating element delivers focused ultrasound which is focused in at least one dimension. The ablating device may also have a number of ablating elements with different characteristics such as focal length.

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Номер записи: 11

22-11-2012 дата публикации

Methods and devices for diastolic assist

Номер: US20120296153A1

Автор: Celina Yong, Freddy Abnousi, Michael D. Laufer

Принадлежит: NSYZ

The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff.

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Номер записи: 12

06-12-2012 дата публикации

Systems and methods for determining location of an access needle in a subject

Номер: US20120310052A1

Автор: George T. Gillies, Jason Tucker-Schwartz, Srijoy Mahapatra

Принадлежит: UNIVERSITY OF VIRGINIA PATENT FOUNDATION

Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be used to provide cardiac waveform information of the subject. A current location of the needle may be distinguished from another location based on an algorithm including the pressure frequency information and the cardiac waveform information.

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Номер записи: 13

06-12-2012 дата публикации

Medical device

Номер: US20120310227A1

Автор: Yukitoshi Katou

Принадлежит: Terumo Corp

A medical device includes a steering unit at a proximal portion of a catheter to steer operations of a heating unit at a distal portion of the catheter. The steering unit includes a main body portion interlocked with the catheter; a slide portion interlocked with the heating unit and slidable relative to the main body portion; a guide unit interlocked with the main body portion and fixed to the slide portion for movement therewith; and an input connector electrically connected with the heating unit and connectable with an output connector for supplying electric energy to the heating unit. The guide unit hinders connection between the input connector and the output connector. A cutout portion enables connection between the input and output connectors when the guide unit moves with respect to the main body portion and the heating unit moves to a position at which the biological tissue is heatable.

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Номер записи: 14

31-01-2013 дата публикации

Catheter with flow balancing valve

Номер: US20130030385A1

Автор: Jeffrey W. Schultz, Michael Olen Zirkle

Принадлежит: Biosense Webster Israel Ltd

A catheter has at least two irrigated ablation electrodes and a coaxial irrigation tubing to transport fluid to the electrodes by separate and dedicated flow paths. A valve is used to control flow of fluid into the coaxial irrigation tubing by means of a plunger assembly that allows fluid to flow through one lumen of the coaxial irrigation tubing while regulating the flow into the other lumen of the coaxial irrigation tubing in response to the fluid flow rate and pressure applied to the plunger assembly.

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Номер записи: 15

31-01-2013 дата публикации

Intracardiac tools and methods for delivery of electroporation therapies

Номер: US20130030430A1

Автор: Jordon D. Honeck, Mark T. Stewart

Принадлежит: MEDTRONIC ABLATION FRONTIERS LLC

A medical system, including a medical device having a plurality of deployable arms, and at least one electrode on at least one of the plurality of arms; and an electric signal generator in communication with the medical device, the electric signal generator programmed to deliver pulsed energy to the medical device sufficient to induce irreversible electroporation ablation.

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Номер записи: 16

21-02-2013 дата публикации

Cardiac Electrosurgery

Номер: US20130046305A1

Автор: Gareth Davies

Принадлежит: Baylis Medical Co Inc

Devices and methods are disclosed for providing access to the pericardial cavity while reducing risk of myocardial damage. The methods include maintaining the positions of a puncture device and of a portion of a parietal pericardium relative to one other while delivering energy from the puncture device to create a channel through the pericardium. Additional embodiments disclosed include delivering a pulse or pulses of energy to the parietal pericardium and attempting to advance the puncture device through the parietal pericardium between deliveries of energy pulses.

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Номер записи: 17

21-03-2013 дата публикации

Cardio mapping system and method for cardio mapping

Номер: US20130072774A1

Автор: Allan M. Greenspan

Принадлежит: Albert Einstein Healthcare Network

A method and system for determining the mechanism of cardiac arrhythmia in a patient is disclosed. The method basically entails measuring the impedance of cardiac tissue in a portion of the patient's heart using a catheter during an episode of supraventricular tachycardia to produce an iso-impedance map of that cardiac tissue on a video display and analyzing the pattern of the iso-impedance map to differentiate focal arrhythmia caused by a circumscribed region of focal firing and reentrant arrhythmia caused by a macroreentrant circuit. The method can also be used to identify regions of coherent rapidly conducting tissue e.g., Bachman's bundle or the inferoposterior pathway insertion points, to identify focal “mother rotors” throughout the left atrium that may participate in the generation and maintenance of atrial fibrillation and to identify areas of CAFE (complex atrial/fractionated electrograms) that truly reflect these mother rotors.

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Номер записи: 18

25-04-2013 дата публикации

Method and apparatus for performing transesophageal cardiovascular procedures

Номер: US20130103018A1

Автор: Sameh Mesallum

Принадлежит: Microaccess Inc

An apparatus for performing a transesophageal cardiovascular procedure includes an elongated tubular main access device having a first lumen with an open proximal end and a distal side opening, and a second lumen with a rigid outer wall and a collapsible inner wall. The second lumen is adapted to receive an elongated probe or surgical device. The apparatus further includes an inflatable sealing means on the outside of the main access device above and below the side opening, and a first fluid conduit extending along the main access device for inflating the sealing means so that when the main access device is inserted into a patient's esophagus and the sealing means are inflated. The portion of the esophagus opposite the side opening is isolated from the remainder of the esophagus above and below the side opening.

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Номер записи: 19

02-05-2013 дата публикации

Cryogenic balloon device with radiofrequency tip

Номер: US20130110098A1

Автор: Jean-Pierre Lalonde

Принадлежит: MEDTRONIC CRYOCATH LP

An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.

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Номер записи: 20

16-05-2013 дата публикации

Integrative atrial fibrillation ablation

Номер: US20130123773A1

Автор: Yitzhack Schwartz

Принадлежит: Biosense Webster Israel Ltd

Cardiac tissue ablation is carried out by defining first regions containing first locations including ganglionated plexi in a heart of a living subject, and inserting a probe into the heart. The method is further carried out by detecting electrical activity in the heart via electrodes on the distal portion of the probe, defining second regions having second locations, wherein the electrical activity exhibits a dominant frequency that is higher than a predefined threshold, defining third regions having third locations, wherein the electrical activity exhibits complex fractionated atrial electrograms, constructing an electroanatomical map of the heart that defines intersections of the first regions and at least one of the second regions and the third regions, selecting ablation sites within the intersections, and ablating cardiac tissue at the ablation sites.

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Номер записи: 21

13-06-2013 дата публикации

Pfo closing device

Номер: US20130150850A1

Автор: Seiichi OOTSUBO

Принадлежит: Terumo Corp

A PFO closing device includes: a clamper including a stick portion provided at a distal portion of a catheter for sticking to a foramen ovale valve and a sandwich member for sandwiching a biological tissue composed of the foramen ovale valve and an atrial septum secundum in cooperation with the stick portion; a cautery device including at least one electrode portion to be inserted into the foramen ovale between the foramen ovale valve and the atrial septum secundum; and an electric energy supply unit for supplying electric energy to the electrode portion, wherein the electrode portion is inserted into the foramen ovale and at the same time, the foramen ovale valve and the atrial septum secundum are sandwiched by the clamper, electric energy is supplied from the electric energy supply unit to the electrode portion and the foramen ovale valve and the atrial septum secundum are mutually fused.

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Номер записи: 22

04-07-2013 дата публикации

Catheter with atraumatic tip

Номер: US20130172786A1

Автор: Eric S. Olson, James V. Kauphusman, Linda K. Nemec, Troy T. Tegg

Принадлежит: St Jude Medical Atrial Fibrillation Division Inc

A medical device is provided comprising a shaft comprising a first segment and a second segment. The first segment is configured to buckle upon application of a first critical force. The second segment includes an outer surface and an inner surface and is configured to buckle upon application of a second critical force. The second critical force is lower than the first critical force. The medical device further comprises a coil disposed radially inwardly of the inner surface of the second segment.

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Номер записи: 23

11-07-2013 дата публикации

Enhanced medical device for use in bodily cavities, for example an atrium

Номер: US20130178851A1

Автор: Aldo Antonio Salvestro, Ashkan Sardari, Douglas Goertzen, Fernando Lopes, Jorge Jaramillo, Peter Hawes, Saar Moisa

Принадлежит: Kardium Inc

Systems, methods, and devices allow intravascular or percutaneous mapping, orientation and/or ablation, in bodily cavities or lumens. A device includes elongate members, moveable between an unexpanded configuration and an expanded or fanned configuration. The elongate members form a stack in the unexpanded configuration to fit through a catheter sheath. The elongate members follow respective arcuate or curvilinear paths as advanced from the sheath into the bent or coiled stack configuration, adopting volute, scroll or rho shapes, and may be nested. The elongated members are fanned or radially spaced circumferentially with respect to one another into the expanded or fanned configuration. Transducer elements carried by elongate members sense various physiological characteristics of or proximate tissue, and/or may apply energy to or proximate tissue. The elongate members are rotatable in groups or as a group in the expanded configuration. The device is retractable.

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Номер записи: 24

11-07-2013 дата публикации

Electrophysiological endocardiology tool

Номер: US20130178908A1

Автор: Christoph Hans Huber

Принадлежит: ENDOHEART AG

Apparatus and methods for pacing the heart. The apparatus may include, and the methods may involve, an elongated member having: a delivery lumen that is configured to traverse the heart wall, the lumen having a proximal opening for receiving the instrument and a distal opening for deploying the instrument; and an electrically conductive member that is configured to deliver to the heart wall a current that modifies a contraction frequency. The apparatus may include an access opening closure device that has: a distal end that is configured to be disposed interior the heart and contact endocardial tissue adjacent the access opening; and a proximal end that is configured to be disposed exterior the heart and contact heart tissue adjacent the access opening; and an electrode that is configured to discharge electrical energy into the heart wall to change the frequency. The apparatus may include an injectable needle pacing electrode.

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Номер записи: 25

15-08-2013 дата публикации

Treatment of cardiac arrhythmia utilizing ultrasound

Номер: US20130211436A1

Автор: Eugene A. Larson, Perry W. Kaminski

Принадлежит: Sonorhythm LLC

A noninvasive or minimally invasive treatment of cardiac arrhythmia such as supraventricular and ventricular arrhythmias, specifically atrial fibrillation and ventricular tachycardia, by treating the tissue with heat produced by ultrasound, including High Intensity Focused Ultrasound or HIFU. A transducer inside the body emits a pulse to assist in focusing the HIFU pulse at the proper location to treat the desired tissue.

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Номер записи: 26

17-10-2013 дата публикации

Haptic system for balloon tipped catheter interventions

Номер: US20130274712A1

Автор: Stuart O. Schecter

Принадлежит: Individual

Embodiments of this invention include hand-held handles and systems for balloon-tipped catheter interventions that enable a user to appreciate a combination of palpable sensations as though his or her hand is actual anatomic tissue in situ in real time. The system may include a haptic handle coupled to the proximal end of the catheter where the haptic handle includes a balloon-shaped haptic interface that exhibits geometric characteristics reflecting an anatomy of the interventional balloon and provides tangible sensations representative of tissues surrounding the interventional balloon. Multiple sensors and actuators may be used to create a non-virtual, transparent experience communicated to a user with a three dimensional, volumetric haptic display. In one embodiment, the sensors are positioned about or within an inflatable balloon positioned at the distal aspect of an inserted catheter used to treat cardiac and vascular diseases such as coronary or peripheral vascular occlusion and ablation of cardiac tissue.

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Номер записи: 27

14-11-2013 дата публикации

Enhanced medical device for use in bodily cavities, for example an atrium

Номер: US20130304065A1

Автор: Aldo Antonio Salvestro, Ashkan Sardari, Douglas Wayne GOERTZEN, Fernando Luis De Souza Lopes, Jorge Jaramillo, Peter Josiah Hawes, Saar Moisa

Принадлежит: Kardium Inc

Systems, methods, and devices allow intravascular or percutaneous mapping, orientation or ablation, or combinations thereof in bodily cavities or lumens. A device includes a plurality of elongate members which are moveable between an unexpanded configuration, a bent or coiled stack configuration and an expanded or fanned configuration. The elongate members form a stack arrangement in the unexpanded configuration to fit through a catheter sheath. The elongate members follow respective arcuate or curvilinear paths as advanced from the sheath into the bent or coiled stack configuration, adopting volute, scroll or rho shapes, and may be nested. The elongated members are fanned or radially spaced circumferentially with respect to one another into the expanded or fanned configuration. Transducers carried by elongate members may sense various physiological characteristics of or proximate tissue, for instance temperature, and/or may apply energy to or proximate tissue, for example to perform ablation. The device is retractable.

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Номер записи: 28

05-12-2013 дата публикации

Operating system with haptic interface for minimally invasive, hand-held surgical instrument

Номер: US20130321262A1

Автор: Stuart O. Schecter

Принадлежит: Stuart O. Schecter

A haptic system for a minimally invasive, hand-held surgical instrument and the system's various parts including a graphical user haptic interface, one or more haptic interfaces associated with a hand-held handle used to control a sensorized end-effector of the surgical instrument or inserted catheters, associated hardware, and an operating system. The system enables users to acquire, read, modify, store, write, and download sensor-acquired data in real time. The system can provide: an open, universally compatible platform capable of sensing or acquiring physiological signals/data in any format; processing of the sensor acquired data within an operating system; and outputting the processed signals to hardware which generates tangible sensations via one or more haptic interfaces. These tangible sensations can be modified by the user in real time as the system ensures the temporal relationship of sensed fiducial events are not altered or shifted relative to the generated and displayed haptic signals.

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Номер записи: 29

02-01-2014 дата публикации

Real time assessment of ablation from electrocardiogram signals

Номер: US20140005664A1

Автор: Assaf Govari, Athanassios Papaioannou

Принадлежит: Biosense Webster Israel Ltd

An apparatus includes an intra-body probe and a processor. The intra-body probe includes an electrode, which is configured to contact tissue in a heart. The processor is configured to receive an electrical signal from the electrode, to distinguish a local component, due to the tissue with which the electrode is in contact, in the electrical signal from a remote-field contribution to the signal, and to control a therapeutic procedure applied to the tissue responsively to the distinguished local component.

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Номер записи: 30

16-01-2014 дата публикации

Devices and Systems for Carotid Body Ablation

Номер: US20140018788A1

Автор: Charles Lennox, Howard Levin, Kenneth M. Martin, Marat FUDIM, Mark Gelfand, Mark Leung, Martin M. GRASSE, Marwan Abboud, Michael Brick MARKHAM, Miriam H. Taimisto, Robert Brommer, Scott H. West, Zoar Jacob ENGELMAN

Принадлежит: Cibiem Inc

Methods and endovascular catheters for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via transmural carotid body ablation.

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Номер записи: 31

23-01-2014 дата публикации

Device and method for the geometric determination of electrical dipole densities on the cardiac wall

Номер: US20140024910A1

Автор: Christoph Scharf, Gunter SCHARF

Принадлежит: Individual

Disclosed are devices, a systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various locations within the associated chamber of the heart.

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Номер записи: 32

23-01-2014 дата публикации

Catheter with strain gauge sensor

Номер: US20140024970A1

Автор: Assaf Govari

Принадлежит: Biosense Webster Israel Ltd

A medical probe, including a flexible insertion tube, having a distal end for insertion into a body cavity of a patient and which is configured to be brought into contact with tissue in the body cavity. The probe further includes a sensor tube of an elastic material, contained inside the distal end of the insertion tube and configured to deform in response to forces exerted by the tissue on the distal end. The probe also includes a plurality of strain gauges fixedly attached to a surface of the sensor tube at different, respective locations and configured to generate respective signals in response to deformations of the sensor tube.

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Номер записи: 33

23-01-2014 дата публикации

Ablation catheter with flexible tip

Номер: US20140025068A1

Автор: Alan de la Rama, Carlo Pappone, Cary Hata, Jared A. Shimizu, Peter Chen

Принадлежит: St Jude Medical Atrial Fibrillation Division Inc

A flexible tip electrode for an ablation catheter is disclosed. The catheter includes a catheter body and a hollow elongate tip electrode disposed at a distal end of the catheter body. The electrode includes a sidewall provided with one or more elongate gaps extending therethrough. The one or more elongate gaps providing flexibility in the sidewall for bending movement of the tip electrode relative to a longitudinal axis of the catheter body.

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Номер записи: 34

06-02-2014 дата публикации

Systems, Methods and Devices Having Stretchable Integrated Circuitry for Sensing and Delivering Therapy

Номер: US20140039290A1

Автор: Bassel de Graff, Roozbeh Ghaffari, William J. Arora

Принадлежит: Individual

System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a the brain, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy. Further, the invention enables the incorporation of both sensing and therapeutic devices on the same substrate allowing for faster treatment of diseased tissue and fewer devices to perform the same procedure.

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Номер записи: 35

20-03-2014 дата публикации

Nearfield ultrasound echography mapping

Номер: US20140081262A1

Автор: David L. Mcgee, Josef V. Koblish

Принадлежит: Boston Scientific Scimed Inc

Various embodiments concern delivering an ablation therapy to different areas of the cardiac tissue and, for each of the areas, sensing an ultrasound signal with at least one ultrasound sensor, the ultrasound signal responsive to the ultrasound energy reflected from the area of cardiac tissue. Such embodiments can further include for each of the plurality of different areas of the cardiac tissue, associating with each area an indication of the degree to which the area of cardiac tissue was lesioned by the delivery of the ablation therapy based on the ultrasound signal and representing a map of the different areas on a display. A user input can select one of the different areas and the indication associated with the selected one area can be represented on the map.

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Номер записи: 36

07-01-2016 дата публикации

METHOD AND APPARATUS FOR PERFORMING TRANSESOPHAGEAL CARDIOVASCULAR PROCEDURES

Номер: US20160000313A1

Автор: Mesallum Sameh

Принадлежит:

An apparatus for performing a transesophageal cardiovascular procedure includes an elongated tubular main access device having a first lumen with an open proximal end and a distal side opening, and a second lumen with a rigid outer wall and a collapsible inner wall. The second lumen is adapted to receive an elongated probe or surgical device. The apparatus further includes an inflatable sealing means on the outside of the main access device above and below the side opening, and a first fluid conduit extending along the main access device for inflating the sealing means so that when the main access device is inserted into a patient's esophagus and the sealing means are inflated. The portion of the esophagus opposite the side opening is isolated from the remainder of the esophagus above and below the side opening. 110.-. (canceled)11. An apparatus for performing a minimally invasive procedure , the apparatus comprising:a first lumen configured to traverse a portion of a patient's esophagus, wherein the first lumen includes an open proximal end and a side opening in a distal end, wherein the opening is configured to be adjacent the patient's esophagus;a second lumen configured to receive any of a device and probe, wherein the second lumen includes a portion configured to direct the any of the device and the probe through the side opening in the distal end of the first lumen; andmeans for generating an opening in the patient's esophagus through the opening in the distal end of the first lumen to thereby provide access to the patient's intra-thoracic cavity from the esophagus, wherein the means for generating the opening is insertable into the second lumen.12. The apparatus of claim 11 , wherein the second lumen is configured to receive the device and to direct the device through the opening in the distal end of the first lumen and through the opening in the patient's esophagus into a intra-thoracic cavity of the patient claim 11 , and wherein the device is configured to ...

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Номер записи: 37

07-01-2021 дата публикации

Medical device for use in bodily lumens, for example an atrium

Номер: US20210000537A1

Автор: Daniel Gelbart, Douglas Wayne GOERTZEN, Fernando Luis De Souza Lopes

Принадлежит: Kardium Inc

A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s).

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Номер записи: 38

02-01-2020 дата публикации

Adjustable clamp systems and methods

Номер: US20200000511A1

Автор: Ara Stephanian, Dwight P. Morejohn, Michael J. Banchieri, Tamer Ibrahim

Принадлежит: Atricure Inc

Tissue treatment systems include an actuator handle assembly coupled with a clamp assembly having a first jaw mechanism and a second jaw mechanism. A first jaw mechanism includes a first flexible boot, a first flexible ablation member coupled with the first flexible boot, and a first rotatable jawbone disposed within the first flexible boot. A second jaw mechanism comprises a second flexible boot, a second flexible ablation member coupled with the second flexible boot, and a second rotatable jawbone disposed within the second flexible boot.

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Номер записи: 39

02-01-2020 дата публикации

Catheter Elements for Bond-Strength Enhancement

Номер: US20200001042A1

Автор: Beeckler Christopher Thomas, Herrera Kevin Justin, Keyes Joseph Thomas

Принадлежит:

A catheter manufacturing method includes the step of providing a hollow cylindrical part of a catheter, having a longitudinal axis, to be bonded to a given part along respective edge surfaces of the hollow cylindrical and the given parts. One or more undercut structures that are disposed circumferentially with respect to the longitudinal axis and also generally parallel to the longitudinal axis, the undercut structures having a radial orientation with respect to the longitudinal axis, are formed at least in the edge surface of the hollow cylindrical part. The hollow cylindrical part and the given part are connected using the undercut structures. 1. A catheter manufacturing method comprising the steps of:providing a hollow cylindrical part of a catheter, having a longitudinal axis, to be bonded to a given part along respective edge surfaces of the hollow cylindrical and the given parts;forming at least in the edge surface of the hollow cylindrical part one or more undercut structures that are disposed circumferentially with respect to the longitudinal axis and also generally parallel to the longitudinal axis, the undercut structures having a radial orientation with respect to the longitudinal axis; andconnecting the hollow cylindrical part and the given part using the undercut structures.2. The manufacturing method according to claim 1 , wherein the step of connecting comprises bonding the hollow cylindrical part and the given part with a bonding material that fills the undercut structures.3. The manufacturing method according to claim 1 , wherein the step of forming comprises forming the undercut structures both in the hollow cylindrical part surface and in the given part surface claim 1 , wherein the given part is another hollow cylindrical part.4. The manufacturing method according to claim 3 , wherein the hollow cylindrical part and the other hollow cylindrical part are configured to operate as a coupler and as a spring.5. The manufacturing method according to ...

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Номер записи: 40

13-01-2022 дата публикации

Balloon catheter and electrophysiological system

Номер: US20220008111A1

Автор: BO Liang, Jiaqiang JIANG, Qiancheng ZHAO, Yiyong Sun, Yunzhu XI

Принадлежит: Shanghai Microport EP MedTech Co Ltd

A balloon catheter (100) and an electrophysiological system, which aim to improve the operability of accurately monitoring the balloon surface temperature at the surface of a double-layered balloon (110). The balloon catheter (100) comprises a catheter body (130), a double-layered balloon (110), at least one temperature measuring element (120), and at least one adhesion piece (140); the temperature measuring element (120) is disposed in an interlayer (113) formed by an inner layer balloon (112) and an outer layer balloon (111); the adhesion piece (140) is adheringly connected to the temperature measuring element (120), and is simultaneously adheringly connected to the inner layer balloon (112) or the outer layer balloon (111); the temperature measuring element (120) is attached to the inner layer balloon (112) or the outer layer balloon (111) by means of the adhesion piece (140); when the double-layered balloon (110) is deformed, the adhesion piece (140) may be displaced relative to the inner layer balloon (112) or outer layer balloon (111) connected to the adhesion piece (140), which enables the temperature measuring element (120) to be displaced relative to the inner layer balloon (112) or outer layer balloon (111) connected to the adhesion piece (140).

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Номер записи: 41

01-01-2015 дата публикации

Method and Devices for Treating Atrial Fibrillation by Mass Ablation

Номер: US20150005694A1

Автор: David E. Francischelli, James R. Skarda, Mark T. Stewart

Принадлежит: MEDTRONIC INC

Apparatus and method for ablating target tissue including a non-linear area of tissue in the left atrium of a patient. The method can include selecting an ablation apparatus having an ablator with a tissue engagement section, penetrating a chest cavity of the patient, and identifying the target tissue. The method can also include positioning the ablation apparatus adjacent to the target tissue so that the tissue engagement section can transfer ablation energy to the target tissue. The method can further include energizing the tissue engagement section with ablation energy in order to create a footprint on the non-linear area of tissue in the left atrium and to reduce an overall mass of excitable tissue in the left atrium.

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Номер записи: 42

20-01-2022 дата публикации

Visualization and recordation system interface with virtual ground for biomedical system and methods

Номер: US20220015658A1

Автор: Andres Claudio Altmann, Israel Zilberman, Vadim Gliner

Принадлежит: Biosense Webster Israel Ltd

Methods, apparatus, and systems for medical procedures are disclosed herein. For example, a plurality of analog sensor signals and an analog reference signal are received by an analog-to-digital converter to produce respective digitized versions of the analog sensor signals. The respective digitized versions of the analog sensor signals are digital filtered to produce respective filtered digitized versions of the analog sensor signals. The filtered digitized versions of the analog sensor signals are output to a visualization system to provide real time display thereof. The filtered digitized versions of the analog sensor signals are communicated to a digital-to-analog converter to produce an analog version of the filtered digitized versions of the analog sensor signals. The analog version of the filtered digitized versions of the analog sensor signals along with the analog reference signal are output to a recordation system to provide supplemental processing and storage thereof.

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Номер записи: 43

20-01-2022 дата публикации

Catheter and Method for Focal Cardiac Ablation by Irreversible Electroporation

Номер: US20220015826A1

Автор: De Kock Andrew L., KOOP BRENDAN E., Maierhofer Edward J., Shuros Allan C.

Принадлежит:

A catheter for focal cardiac ablation by irreversible electroporation includes a flexible catheter body, a plurality of tines disposed at a distal end of the catheter body, a flexible shaft, a return electrode, and an electrical conductor. The plurality of tines are formed of an electrically conductive material and configured to deploy from a lumen at the distal end of the catheter body. Each tine of the plurality of tines is configured to self-bias from a linear configuration within the lumen to a curved configuration when deployed from the lumen. The shaft is mechanically and electrically coupled to the plurality of tines. The shaft is configured to deploy the tines from the lumen when the shaft is moved toward the distal end of the catheter body. The return electrode is disposed on an outer surface of the catheter body. The electrical conductor is electrically coupled to the return electrode. 1. A catheter for focal cardiac ablation by irreversible electroporation , the catheter comprising:a flexible catheter body extending from a proximal end to a distal end, the catheter body forming a lumen extending from the proximal end to the distal end, the catheter body defining a longitudinal axis;a plurality of tines disposed at the distal end of the catheter body, the plurality of tines formed of an electrically conductive material and configured to deploy from the lumen at the distal end of the catheter body, each tine of the plurality of tines configured to self-bias from a linear configuration within the lumen to a curved configuration when deployed from the lumen, each tine of the plurality of tines forming a curve extending from the distal end of the catheter body and away from the longitudinal axis in the curved configuration;a flexible shaft formed of an electrically conductive material, the shaft mechanically and electrically coupled to the plurality of tines and extending through the lumen from the proximal end of the catheter body, the shaft configured to ...

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Номер записи: 44

12-01-2017 дата публикации

STEERABLE ENDOLUMINAL PUNCH

Номер: US20170007288A1

Автор: Breznock Eugene M.

Принадлежит: Indian Wells Medical, Inc.

A transseptal punch with a steering mechanism within the punch, such that punch can be steered and deflected within a guide catheter during delivery, to avoid skiving of the guide catheter inner wall by passage of the punch tip through the guide catheter. The punch can be advanced through a body lumen in its straight configuration and then be selectively articulated or curved to permit negotiation of tortuous curvature or to permit optimal approach or access to a puncture site. The punch is able to create holes in the atrial septum of the heart or other structures and is easier to use than punches that are pre-curved near their distal tip since it is easier to advance through accessory catheters. 1. A transseptal punch system for penetrating the atrial septum of a patient , said system comprising:a guide catheter adapted for insertion into the right atrium of a patient's heart, said guide catheter characterized by a distal end, and proximal end, and a guide catheter lumen extending from the distal end to the proximal end; an outer tube, said outer tube characterized by a distal end and a proximal end, and an outer tube lumen extending from the distal end to the proximal end thereof, said outer tube having a flexible region near the distal end of the outer tube;', 'a control rod disposed within the outer tube, said control characterized by a distal end and a proximal end;', 'wherein the control rod is fixed to the distal end of the outer tube; and, 'a transseptal punch, said transseptal punch having a distal end and a proximal end, said transseptal punch fitting within the guide catheter lumen and being longitudinally advanceable within the guide catheter, said punch comprisingan inner tube fixed to the distal end of the outer tube, said inner tube having a sharp point for penetrating the atrial septum of the patient.2. The system of wherein:the control rod is fixed to the distal end of the outer tube, at a point distal to the flexible region.3. The system of wherein ...

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Номер записи: 45

14-01-2016 дата публикации

Mapping ablation catheter

Номер: US20160008060A1

Автор: Young Hoon Kim

Принадлежит: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

A mapping ablation catheter is provided comprising: a catheter conduit having a hollow inner space in which a guide member is disposed; a monitoring electrode unit arranged to surround the outer circumferential surface of the distal portion of the catheter conduit and perform a mapping on the lesion region by being in side-contact with a cardiac organ; an ablation electrode unit arranged to be spaced apart from the monitoring electrode unit and surround the outer circumferential surface of the distal portion of the catheter conduit and which removes the lesion region; a plurality of liquid discharge holes arranged on the outer circumferential surface of the ablation electrode; a current application unit which applies current to the monitoring electrode unit and the ablation electrode unit; and a liquid supply unit having a liquid supply tube, one end of the liquid-supply tube connected to the liquid discharge holes in the catheter conduit.

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Номер записи: 46

14-01-2016 дата публикации

ULTRASOUND IMAGING SHEATH AND ASSOCIATED METHOD FOR GUIDED PERCUTANEOUS TRANS-CATHETER THERAPY

Номер: US20160008636A1

Автор: Warnking Reinhard J.

Принадлежит:

Intra-organ ultrasound images are obtained by integrating ultrasound array configurations at the distal region of a sheath or guiding catheter integral to any catheter based intervention. A dual mode ablation/imaging circular ultrasound array is used to create circular or partial circular lesions. The sites of the individual lesion segments are identified in an ultrasound 2D image. In the case of PV isolation the process of ablating individual segments identified in the ultrasound image is repeated until a circumferential, continuous lesion has been achieved and PV isolation has been confirmed with the coaxial loop sensing catheter which also serves as a guide wire. 1. A method of treating atrial fibrillation (AF) of a mammalian subject , comprising the steps of:(a) providing a dual mode therapy/imaging unit incorporating a plurality of electromechanical transducers adapted for producing and detecting ultrasonic vibrations and arranged in an at least partial cylindrical array;(b) positioning said dual mode therapy/imaging unit within an antrum of a pulmonary vein (PV) to apply energy to one segment of a circular cross section proximal to the PV annulus; and(b) repeatedly actuating said dual mode therapy/imaging unit to apply energy of about 50 to 100 W per square cm in a range of frequencies about 10 MHz to each of a plurality of portions of a circular cross section within the PV antrum until a complete circumferential lesion has been achieved.2. A method as set forth in wherein the positioning and actuating steps are performed while the heart is beating.3. A method as set forth in claim 1 , further comprising operating said dual mode therapy/imaging unit in an imaging mode to obtain ultrasound image data and operating a computer to display an ultrasound image from said data claim 1 , wherein the step of actuating said dual mode therapy/imaging unit is performed for an ablation section selected from the displayed ultrasound image.4. A method as set forth in claim 3 ...

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Номер записи: 47

11-01-2018 дата публикации

ASCERTAINING TISSUE THICKNESS

Номер: US20180008229A1

Автор: Altmann Andres, Govari Assaf, Volkinshtein Dmitry

Принадлежит:

Embodiments described herein include apparatus that includes an electrical interface and a processor. The processor is configured to receive, via the electrical interface, a first signal that indicates a time-varying force that was applied to a portion of tissue, and one or more second signals that are derived from ultrasound reflections received from the portion of tissue. The processor is further configured to learn, from the first signal and the second signals, a dependency of a thickness of the portion of tissue on the force applied to the portion of tissue. Other embodiments are also described. 1. Apparatus , comprising:an electrical interface; and [ a first signal that indicates a time-varying force that was applied to a portion of tissue, and', 'one or more second signals that are derived from ultrasound reflections received from the portion of tissue, and, 'to receive, via the electrical interface, 'to learn, from the first signal and the second signals, a dependency of a thickness of the portion of tissue on the force applied to the portion of tissue., 'a processor, configured2. The apparatus according to claim 1 , wherein the processor is further configured to generate claim 1 , based on the learned dependency claim 1 , an output indicating at least one recommended parameter for an ablation of the portion of tissue performed at a particular contact force.3. The apparatus according to claim 2 , wherein the processor is configured to generate the output by:based on the learned dependency, estimating a thickness of the portion of tissue that would result from the particular contact force being applied to the portion of tissue during the ablation of the portion of tissue, andin response to the estimated thickness, generating the output.4. The apparatus according to claim 2 , wherein the recommended parameter includes a power of an ablating signal.5. The apparatus according to claim 2 , wherein the recommended parameter includes a duration of an ablating signal ...

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Номер записи: 48

14-01-2021 дата публикации

Medical device and treatment method

Номер: US20210007790A1

Автор: Tomoaki Takemura, Yukitoshi Kato, Yusuke Takahashi

Принадлежит: Terumo Corp

A medical device and a treatment method, in which energy is accurately applied to a target site by suppressing a positional displacement between an expansion body and a biological tissue. The medical device includes an elongated shaft portion and an expansion body disposed in a distal portion of the shaft portion and configured to expand and contract in a radial direction. The expansion body includes a holding portion having a proximal side holding portion and a distal side holding portion configured to hold the biological tissue, and a movable portion configured to open and close the holding portion.

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Номер записи: 49

14-01-2021 дата публикации

Medical device

Номер: US20210007791A1

Автор: Nozomu Yamazaki, Tomoaki Takemura, Yukitoshi Kato, Yusuke Takahashi

Принадлежит: Terumo Corp

A medical device is disclosed which can suppress torsion of a wire in a circumferential direction in an expansion body formed using the wire. The medical device includes an elongated shaft portion, and an expansion body disposed in a distal portion of the shaft portion, the expansion body configured to expand and contract in a radial direction. The expansion body has wire portions in which a distal portion and a proximal portion are linked with the shaft portion, and a holding portion formed using at least one of the wire portions, and holding a biological tissue. At least one of a proximal side and a distal side of the holding portion has an opening portion formed using a wire portion or formed using a plurality of the wire portions. When the expansion body expands, the wire portion forming the holding portion faces the opening portion.

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Номер записи: 50

11-01-2018 дата публикации

MAGNETIC NAVIGATION SYSTEMS AND METHODS

Номер: US20180008342A1

Автор: Ibrahim Tamer, Swanson David K.

Принадлежит:

Systems and methods for forming a lesion on an endocardial tissue of a patients heart involve placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, and placing a guiding assembly outside of the heart. An ablation assembly includes an ablation element and a first attraction element, and a guiding assembly includes a second attraction element. First and second attraction elements can be attracted via magnetism. Techniques involve forming an ablation on the cardiac tissue of a patient's heart with an ablation element of the ablation assembly. Optionally, techniques may include moving the second attraction element of the guiding assembly relative to the patient's heart, so as to effect a corresponding movement of the ablation element of the ablation assembly. 1placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, the ablation assembly comprising an ablation element, a support structure, and a first attraction element;placing a guiding assembly outside of the heart, the guiding assembly comprising a second attraction element, such that a magnetic attraction is present between the first and second attraction elements, and the support structure of the ablation assembly forms a space between the ablation element and the endocardial tissue; andforming the lesion on the endocardial tissue of the patient's heart with the ablation element of the ablation assembly while the support structure isolates the ablation element from blood flowing in the patient's heart.. A method of forming a lesion on an endocardial tissue of a patients heart, comprising: This application is a continuation of U.S. application Ser. No. 131862,996 filed Apr. 15, 2013, which is a continuation of U.S. patent application Ser. No. 12/781,072 filed May 17, 2010 (now U.S. Pat. No. 8,430,875 issued Apr. 30, 2013) entitled “MAGNETIC NAVIGATION SYSTEMS AND METHODS,” which is a nonprovisional application of, and claims the benefit of the filing ...

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Номер записи: 51

11-01-2018 дата публикации

APPARATUS AND METHOD FOR INTRA-CARDIAC MAPPING AND ABLATION

Номер: US20180008343A1

Автор: Gelbart Daniel, Lichtenstein Samuel Victor

Принадлежит:

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a Maze procedure. The location of the ports and valves is based on using the convective cooling effect of the blood flow. The mapping can be performed by a catheter-deployed expandable net or a scanning catheter. The same net or catheter can also perform the ablation procedure. 1. (canceled)2. A method comprising:providing a structure and a plurality of elements arranged on the structure;activating at least a group of elements in the plurality of elements to generate heat, each element in the group of elements activated to generate heat sufficient to cause an increase in temperature above blood temperature but insufficient to cause tissue ablation;displaying a representation of a first spatial distribution of at least the group of elements; anddisplaying, for each particular element in the group of elements, respective information related to the heat generated by the activation of the particular element.3. The method of claim 2 , comprising displaying claim 2 , for each particular element in the group of elements claim 2 , the respective information related to the heat generated by the activation of the particular element at least proximate a location of the particular element in the displayed first spatial distribution of at least the group of elements.4. The method of claim 2 , comprising displaying all of the respective information for all elements in the group of elements according to a second spatial distribution claim 2 , the second spatial distribution corresponding to the first spatial distribution of at least the group of elements.5. The method of claim 2 , comprising displaying claim 2 , for each particular element in the group of elements claim 2 , the respective information related to the heat ...

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Номер записи: 52

27-01-2022 дата публикации

System(s), method(s) and device(s) for the prevention of esophageal fistula during catheter ablation

Номер: US20220022993A1

Автор: Colin Brahmstedt, Fergus Wong, Matthew Kuhn, William Cohn

Принадлежит: Ethicon Inc

The present invention is directed to systems, devices and methods for trans-septally delivering carbon dioxide through a minimally invasive catheter to create a gaseous pocket or emphysema between the posterior wall of the left atrium and the esophagus during cardiac ablation of the left atrium. This pocket of gas expanded tissue serves to thermally insulate and separate the esophagus from the left atrium during ablation to prevent the formation of an atrial-esophageal fistula. The system comprises a control system to precisely deliver the gas to a desired location through a needle-based catheter assembly.

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Номер записи: 53

10-01-2019 дата публикации

FEEDBACK SYSTEM FOR CRYOABLATION OF CARDIAC TISSUE

Номер: US20190008572A1

Автор: BISCHOF John C., GROVES Regina E., Iaizzo Paul A., LALONDE Jean-Pierre, LASKE Timothy G.

Принадлежит:

A method and system for providing lesion depth feedback during an ablation procedure. In particular, the method and system provide feedback data or information relating to lesion depth in myocardial tissue during a cryoablation procedure. A plurality of tissue temperature measurements may be transmitted from a plurality of thermocouples disposed on a cryotreatment element, which measurements may be used to determine a slope of change in temperature sensed by each thermocouple over time. The circulation of coolant through the treatment element may be adjusted when the slope changes. A change in slope may indicate that the cryoablation temperatures have passed through target myocardial tissue into non-target, non-myocardial tissue, which may result in collateral damage to structures near the heart. 1. A method for assessment of ablation lesion depth in myocardial tissue , the method comprising:taking a plurality of temperature measurements with one or more thermocouples;determining a rate of change in temperature for each of the one or more thermocouples; andadjusting a temperature of a treatment element in contact with the myocardial tissue when the rate of change in temperature changes.2. The method of claim 1 , wherein the temperature of the treatment element is adjusted when the rate of change in temperature increases negatively.3. The method of claim 1 , wherein the temperature of the treatment element is adjusted when the rate of change in temperature decreases.4. The method of claim 2 , wherein the treatment element is a cryoballoon claim 2 , and the one or more thermocouples are disposed on the cryoballoon.5. The method of claim 4 , wherein the cryoballoon is in fluid communication with a coolant supply reservoir.6. The method of claim 5 , wherein adjusting the temperature of the treatment element includes adjusting a flow of coolant within the cryoballoon.7. The method of claim 6 , wherein adjusting the flow of coolant includes at least one of stopping and ...

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Номер записи: 54

09-01-2020 дата публикации

MULTIPLEXING OF HIGH COUNT ELECTRODE CATHETER(S)

Номер: US20200008705A1

Автор: Baron Oded, Benaroya Yoav, Urman Roy, Ziv-Ari Morris

Принадлежит: Biosense Webster (Israel) Ltd.

A method is disclosed comprising: performing a first scan of an organ using a set of electrodes in a catheter that are currently active; deactivating one or more of the electrodes in the set based on data that is collected as a result of the first scan; tuning the set by at least one of (i) deactivating one or more electrodes in the set that remain active after the deactivating, and (ii) activating one or more electrodes in the catheter that are inactive; performing a second scan of the organ using electrodes in the set that are currently active after the tuning is performed, and generating a map of the organ based on data collected as a result of the second scan; and outputting the map of the organ for presentation to a user. 1. A method comprising:performing a first scan of an organ using a set of electrodes in a catheter that are currently active;deactivating one or more of the electrodes in the set based on data that is collected as a result of the first scan;tuning the set by at least one of (i) deactivating one or more electrodes in the set that remain active after the deactivating, and (ii) activating one or more electrodes in the catheter that are inactive;performing a second scan of the organ using electrodes in the set that are currently active after the tuning is performed, and generating a map of the organ based on data collected as a result of the second scan; andoutputting the map of the organ for presentation to a user.2. The method of claim 1 , wherein the organ is a heart.3. The method of claim 1 , wherein deactivating one or more of the electrodes in the set based on data that is collected as a result of the first scan includes deactivating one or more electrodes that are not in physical contact with tissue of the organ that is part of one or more regions of interest in the organ.4. The method of claim 1 , wherein deactivating one or more of the electrodes in the set based on data that is collected as a result of the first scan includes ...

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Номер записи: 55

03-02-2022 дата публикации

Controlled and precise treatment of cardiac tissues

Номер: US20220031378A1

Автор: Landy Toth, Robert S. Schwartz

Принадлежит: Individual

Compositions, systems, devices, and methods for performing precise chemical treatment of tissues are disclosed. Systems, devices, and methods for administering a chemical agent to one or more a precise regions within a tissue mass are disclosed. Compositions, systems, devices, and methods for treating targeted regions within a tissue mass are disclosed. Systems, devices, and methods for identifying, localizing, monitoring neural traffic in the vicinity of, quantifying neural traffic in the vicinity of, and mapping neural traffic near targeted regions within a tissue mass are disclosed.

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Номер записи: 56

03-02-2022 дата публикации

AUTOMATICALLY PERFORMING IRREVERSIBLE ELECTROPORATION ABLATION DURING HEART REFRACTORY PERIOD

Номер: US20220031385A1

Автор: Govari Assaf

Принадлежит:

A method includes inserting an ablation catheter into an ablation site in a patient heart. Multiple electrocardiogram (ECG) signals are acquired. A refractory period of the patient heart is detected based on the acquired ECG signals. The ablation site is ablated using the ablation catheter during the detected refractory period. 1. A method for performing irreversible electroporation during heart refractory period , the method comprising:inserting an ablation catheter into an ablation site in a patient heart;acquiring multiple electrocardiogram (ECG) signals;detecting, based on the acquired ECG signals, a refractory period of the patient heart; andablating the ablation site using the ablation catheter during the detected refractory period.2. The method according to claim 1 , wherein acquiring the multiple ECG signals comprises acquiring at least one of (i) intra-cardiac (IC) ECG signals at the ablation site claim 1 , and (ii) body-surface (BS) ECG signals.3. The method according to claim 1 , wherein detecting the refractory period comprises indicating a sinus rhythm in at least one of the acquired ECG signals.4. The method according to claim 1 , wherein ablating the ablation site comprises applying one or more irreversible electroporation (IRE) pulses to tissue at the ablation site during the detected refractory period.5. The method according to claim 4 , wherein applying the one or more IRE pulses comprises controlling an IRE pulse generator and applying the IRE pulses to the tissue in response to receiving at least one of the ECG signals that is indicative of the sinus rhythm.6. A system for performing irreversible electroporation during heart refractory period claim 4 , the system comprising:one or more electrodes, which are configured to sense multiple electrocardiogram (ECG) signals of a patient heart; anda processor, which is configured, based on the acquired ECG signals, to detect a refractory period of the patient heart, and to control ablation at an ablation ...

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Номер записи: 57

03-02-2022 дата публикации

Cautious irreversible-electroporation (ire) protocol for avoiding bubble generation

Номер: US20220031387A1

Автор: Assaf Govari

Принадлежит: Biosense Webster Israel Ltd

An irreversible electroporation (IRE) includes setting an initial IRE protocol for applying IRE pulses by electrodes of a catheter placed in contact with tissue in an organ. A notification is issued to a user upon determining that the initial IRE protocol is expected to cause bubbles in blood. In response to the notification, user input is received from the user, that selects between the initial IRE protocol and an alternative protocol that is not expected to cause the bubbles. The IRE pulses are applied according to the initial IRE protocol or the alternative IRE protocol, depending on the user input.

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Номер записи: 58

03-02-2022 дата публикации

CATHETER WITH SERIALLY CONNECTED SENSING STRUCTURES AND METHODS OF CALIBRATION AND DETECTION

Номер: US20220032009A1

Автор: Clark Jeffrey L., Kamin George, Stanley Mark

Принадлежит:

A catheter is responsive to external and internal magnetic field generators for generating signals representing position and pressure data, with a reduced number of sensing coil leads for minimizing lead breakage and failure. The catheter includes a flexible joint with pressure sensing and position coils, at least pair of a pressure sensing coil and a position coil are serially connected. Methods of calibrating a catheter for position and pressure sensing, and detecting magnetic field interference with one catheter by another catheter or other metal or ferrous object advantageously use signals between two sets of sensors as a “back up” or “error check”. 1. A catheter for use with a catheterization system having a plurality of external magnetic field generators , each generating a position-data magnetic field , comprising:a flexible tubing; and a proximal portion, a distal portion and a flexible joint between the proximal portion and the distal portion;', 'an internal magnetic field generator positioned in one of the proximal and distal portions, the internal magnetic field generator generating a pressure-data magnetic field;', 'three first sensing coils and two second sensing coils positioned in the other of the proximal and distal portions, one of the three first sensing coils and the two second sensing coils adapted to sense the pressure-data magnetic field and generate signals representative of data relating to pressure exerted on the distal section when engaged with tissue, the other of the three first sensing coils and the two second sensing coils adapted to sense each of the position-data magnetic fields and generate signals representative of data relating to position of the distal section, each of the three first sensing coils being generally parallel with a longitudinal axis of the other of the proximal and distal portion and being located in a first axial section of the other of the proximal and distal portion at different azimuthal angles about the ...

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Номер записи: 59

19-01-2017 дата публикации

ESTIMATION OF LESION SIZE

Номер: US20170014181A1

Автор: Bar-Tal Meir, Constantine Garth Francis, Nakagawa Hiroshi, Rubissa Assaf, Silberschein Erez

Принадлежит:

A method, consisting of ablating tissue for a time period, measuring a contact force applied during the time period, and measuring a power used during the time period. The method further includes ceasing ablating the tissue when a desired size of a lesion produced in the tissue, as estimated using an integral over the time period of a product of the contact force raised to a first non-unity exponent and the power raised to a second non-unity exponent, is reached. 1. A method , comprising:ablating tissue for a time period;measuring a contact force applied during the time period;measuring a power used during the time period; andceasing ablating the tissue when a desired size of a lesion produced in the tissue, as estimated using an integral over the time period of a product of the contact force raised to a first non-unity exponent and the power raised to a second non-unity exponent, is reached.2. The method according to claim 1 , wherein the first non-unity exponent has a value in a range of 0.6-0.8.3. The method according to claim 1 , wherein the second non-unity exponent has a value in a range of 1.4-1.8.4. The method according to claim 1 , wherein the size comprises a volume of the lesion.5. The method according to claim 1 , wherein the size comprises a depth of the lesion.6. The method according to claim 1 , wherein the size comprises a diameter of the lesion.7. The method according to claim 1 , wherein measuring the power comprises measuring a current generating the power.8. Apparatus claim 1 , comprising:a probe configured to ablate tissue for a time period; anda processor configured to:measure a contact force applied by the probe during the time period,measure a power used for ablating the tissue during the time period, andcease ablating the tissue when a desired size of a lesion produced in the tissue, as estimated using an integral over the time period of a product of the contact force raised to a first non-unity exponent and the power raised to a second non- ...

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Номер записи: 60

19-01-2017 дата публикации

METHOD AND DEVICE FOR DETECTION OF ARRHYTHMIAS AND MYOCARDIAL INJURY

Номер: US20170014182A1

Автор: Madjid Mohammad, Razavi Mehdi, WILLERSON James T.

Принадлежит:

Herein disclosed is a method of detecting and identifying the source of abnormal electrical currents in the heart to assist in ablating these currents, comprising the use of contact or non-contact temperature measurement devices. In an embodiment, source of abnormal electrical activity of the heart and its attached arteries and veins show different temperature patterns from normal segments. In an embodiment, the method further comprises analyzing the temperature of the chamber of interest, and determining regions of low or high temperature by extension metabolic activity. In an embodiment, the method comprises measuring myocardial temperature comprising placing an array of thermocouples imbedded on a basket in the cardiac chamber. In an embodiment, the thermocouples are placed in contact with the myocardial tissue. 1. A method of assisting in ablating abnormal electrical currents in a heart , comprisingplacing one or more temperature measurement devices in the heart, wherein said devices utilize contact or non-contact temperature measurement schemes;collecting signals from the one or more temperature measurement devices; anddetecting and identifying a source of abnormal electrical currents in the heart or a chamber of interest.2. The method of wherein source of abnormal electrical activity of the heart and its attached arteries and veins show different temperature patterns from normal segments.3. The method of further comprisinganalyzing the temperature of the chamber of interest, anddetermining regions of low or high temperature by extension metabolic activity.4. The method of comprising measuring myocardial temperature comprising placing an array of thermocouples imbedded on a basket in the cardiac chamber.5. The method of wherein the thermocouples are placed in contact with the myocardial tissue.6. The method of wherein the array of thermocouples comprises a series of flexible splines.7. The method wherein the splines are extended (low profile) so as to be placed ...

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Номер записи: 61

18-01-2018 дата публикации

DIAPHRAGM PUMPS FOR MEDICAL APPLICATIONS

Номер: US20180014878A1

Автор: Algawi Yehuda, Govari Assaf

Принадлежит:

Apparatus and methods described include a pump, which includes a piston, a diaphragm coupled to the piston and defining a wall of a fluid chamber, and a snail cam. The snail cam is configured to, by rotating, alternatingly (i) pump fluid from the fluid chamber, and (ii) draw fluid into the fluid chamber, by driving the piston to move the diaphragm. Other embodiments are also described. 1. A pump , comprising:a piston;a diaphragm coupled to the piston and defining a wall of a fluid chamber; anda snail cam configured to, by rotating, alternatingly (i) pump fluid from the fluid chamber, and (ii) draw fluid into the fluid chamber, by driving the piston to move the diaphragm.2. The pump according to claim 1 , wherein the snail cam is configured to claim 1 , when rotating at a constant speed claim 1 , alternatingly (i) pump fluid from the fluid chamber at a first rate claim 1 , and (ii) draw fluid into the fluid chamber at a second rate that is greater than the first rate.3. The pump according to claim 1 , wherein the snail cam is configured to claim 1 , when rotating at a constant speed claim 1 , during each rotational cycle of the snail cam claim 1 , (i) pump fluid from the fluid chamber for a first amount of time claim 1 , and (ii) draw fluid into the fluid chamber for a second amount of time that is less than the first amount of time.4. The pump according to claim 3 , wherein a ratio of the first amount of time to the second amount of time is at least 4:1.5. The pump according to claim 1 , wherein the snail cam is shaped to define a tooth having a slope of between 50 and 80 degrees.6. The pump according to claim 1 , wherein the snail cam is shaped to define a plurality of teeth.7. The pump according to claim 1 , wherein claim 1 , over a majority of a circumference of the snail cam claim 1 , a rate of increase of a radius of the snail cam is constant.8. Apparatus claim 1 , comprising:a piston;a diaphragm coupled to the piston and defining a wall of a fluid chamber;a ...

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Номер записи: 62

18-01-2018 дата публикации

CATHETERS AND METHODS FOR INTRACARDIAC ELECTRICAL MAPPING

Номер: US20180014883A1

Автор: GROVES Regina E., Knight Joseph Allen, LASKE Timothy G.

Принадлежит:

A method and system capable of identifying ectopic foci, rotors, or conduction pathways involved in reentrant arrhythmias within cardiac tissue, and then treating identified ectopic foci, rotors, and/or pathways with either lethal or sub-lethal temperatures. The system includes a medical device having one or more mapping elements and one or more treatment elements, and a computer programmable to identify ectopic foci and rotors based at least in part on signals received from the one or more mapping elements at one or more locations. 1. A method of locating and treating a source or pathway of electrical conduction within cardiac tissue , the method comprising:(a) positioning one or more mapping elements affixed to a distal end of medical device in contact with cardiac tissue at a first position, the medical device being in communication with a control system including a computer having a display and programmable to execute algorithms, the cardiac tissue being composed of cells;(b) executing computer algorithms to determine directional and morphological features of the electrical conduction of interest based at least in part on signals received by the computer from the one or more mapping elements at the first position;(c) displaying on the computer display a suggested second position at which the one or more mapping elements should be placed in contact with the cardiac tissue;(d) repositioning the one or more mapping elements at the second position;(e) executing computer algorithms to determine directional and morphological features of the electrical conduction of interest based at least in part on signals received by the computer from the one or more mapping elements at the second position;(f) repeating steps (a)-(e) until a source or pathway of the electrical conduction of interest is located; and(g) activating one or more treatment elements in contact with the cardiac tissue cells to treat the cells at a non-lethal temperature and disrupt the source or pathway of ...

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Номер записи: 63

18-01-2018 дата публикации

APPARATUS FOR MANUALLY MANIPULATING HOLLOW ORGANS

Номер: US20180015268A1

Автор: Fojtik Shawn P.

Принадлежит:

An apparatus for mechanically manipulating hollow organs within the body of a subject, or an organ manipulation apparatus, includes a manipulation section. The manipulation section may include a substantially two-dimensional element, which may have a width that exceeds a distance across a portion of the interior of a hollow organ within which the manipulation section is to be positioned. The manipulation section is configured to manipulate at least a portion of a hollow organ from within, which may modify at least one of a shape, orientation, or location of at least part of the hollow organ. Methods for manipulating hollow organs are also disclosed, as are operating techniques, such as left atrial ablation, in which the shapes, orientations, and/or locations of hollow organs are manipulated to move the hollow organs away from the site of the medical procedure, reducing the potential for damage to the hollow organs. 1. An apparatus for manipulating an esophagus , comprising: a distal end;', 'a proximal end opposite from the distal end;', 'a proximal portion adjacent to the proximal end, the proximal portion being substantially linear or substantially curvilinear; and', 'a distal portion adjacent to the distal end, a manipulation section of the distal portion having a substantially two-dimensional configuration defined by a series of bends, the substantially two-dimensional configuration having a width of more than 14 mm., 'an elongate element consisting of2. The apparatus of claim 1 , wherein the elongate element has a substantially solid structure.3. The apparatus of claim 1 , wherein the elongate element is radiopaque.4. The apparatus of claim 1 , wherein the elongate element is a wire.5. The apparatus of claim 1 , wherein the elongate element has a diameter of about 0.035 inch to about 0.038 inch.6. The apparatus of claim 1 , wherein the manipulation section is made of a shape memory alloy.7. The apparatus of claim 1 , wherein the series of bends in the distal ...

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Номер записи: 64

17-01-2019 дата публикации

Transcatheter atrial anchors and methods of implantation

Номер: US20190015205A1

Автор: Jaime Eduardo Sarabia, Vivek RAJAGOPAL, Yenchin LIAO

Принадлежит: Opus Medical Therapies LLC

Anchor assemblies for endovascular introduction and implantation for tethering a replacement heart valve to a cardiac wall. An anchor delivery system introduces the assembly. The anchor may be either implanted with a tether connected thereto or implanted and then connected to a tether. If the latter, a tether assembly is mounted to the implanted anchor to connect the anchor to the valve. The anchors may be implanted into any cardiac wall including the interventricular septum or the epicardial space and the valve may replace the mitral or tricuspid valve.

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Номер записи: 65

17-01-2019 дата публикации

Hybrid Transseptal Dilator and Methods of Using the Same

Номер: US20190015644A1

Автор: Davies Gareth, Leung Linus Hoi Che, Thomspon Smith Melanie

Принадлежит: Baylis Medical Company Inc.

A method and apparatus are disclosed for an optimized transseptal procedure for providing left heart access, that reduces the number of devices that are used in order to minimize procedural time, complexity and cost. The apparatus comprises a hybrid dilator that comprises the combined functionality of a transseptal sheath and dilator assembly. The hybrid dilator comprises: a dilator shaft defining a lumen for receiving a crossing device therethrough, the dilator shaft being structured to provide support for the crossing device when the crossing device is used to create a puncture in a tissue; and a distal tip having an outer diameter which tapers down to an outer diameter of the crossing device for providing a smooth transition between the crossing device and the distal tip when the crossing device is inserted through the lumen and protrudes beyond the distal tip. 1. A hybrid dilator for use with a crossing device in tissue puncturing procedures , the hybrid dilator comprising:a dilator shaft defining a lumen for receiving a crossing device therethrough, the dilator shaft being structured to provide support for the crossing device when the crossing device is used to create a puncture in a tissue; anda distal tip having an outer diameter which tapers down to an outer diameter of the crossing device for providing a smooth transition between the crossing device and the distal tip when the crossing device is inserted through the lumen and protrudes beyond the distal tip.2. The hybrid dilator of claim 1 , wherein the dilator shaft has an outer diameter from about 12 French to about 20 French.3. The hybrid dilator of claim 1 , wherein the dilator shaft has an outer diameter from about 0.414 cm to about 0.421 cm.4. The hybrid dilator of claim 1 , wherein the dilator shaft has an outer diameter from about 0.490 cm to about 0.521 cm.5. The hybrid dilator of claim 1 , wherein the dilator shaft substantially comprises a high density polyethylene.6. The hybrid dilator of claim ...

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Номер записи: 66

16-01-2020 дата публикации

Systems and Methods for Performing Electrophysiology (EP) Signal Processing

Номер: US20200015687A1

Автор: Asirvatham Samuel J., DRAKULIC Budimir S., FAKHAR Sina, Foxall Thomas G., VLAJINIC Branislav

Принадлежит:

Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal. 1. A system , comprising:an electrocardiogram (ECG) circuit board configured to process an ECG signal; anda plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal,wherein the ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components, andwherein the ECG circuit board processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.2. The system of claim 1 , wherein a single Wilson Central Terminal (WCT) signal is used for the ECG circuit board and the plurality of IC circuit boards.3. The system of claim 1 , wherein the ECG circuit board comprises an input protection circuit configured to shunt a voltage of the ECG signal greater than or equal to 300 V.4. The system of claim 1 , wherein the ECG circuit board comprises a radio frequency filter circuit configured to attenuate an amplitude of the ECG signal between about 300 kHz and about 600 kHz.5. The system of claim 3 , wherein the ECG circuit board further comprises a radio frequency filter circuit configured to attenuate an amplitude of the ECG signal between about 300 kHz and about 600 kHz.6. The system of claim 4 , wherein the ECG circuit board further comprises a low-frequency feedback circuit coupled to the ...

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Номер записи: 67

16-01-2020 дата публикации

Selective Stiffening Catheter

Номер: US20200015889A1

Автор: Abelleira Joe, Bales, Deville Derek Dee, Jr. Thomas O., McBrayer M. Sean, Palmer Matthew A., Smith Kevin W.

Принадлежит: Syn Variflex, LLC

A method for operating a catheter provides a mechanical stiffener to a catheter shaft portion, the shaft comprising an inner sheath having a distal end and an outer surface and defining an access lumen extending distally to the distal end and an outer sheath having an inner surface surrounding the inner sheath distally to the distal end, defining an annulus between the outer and inner surfaces, the annulus having a connection at which vacuum applies to the annulus, and having a substantially constant outer diameter over the portion to the distal end. A tool is shaped and sized to pass through the access lumen and past the distal end. The portion is placed in an increased stiffened state by applying vacuum to create a stable base with at least a shaft segment within the anatomy that atraumatically resists reaction forces applied to the shaft by the tool. 1. A method for operating an anatomical catheter , comprising: [ having a distal end and an outer surface; and', 'defining an access lumen having a given diameter and extending distally to the distal end; and, 'an inner sheath, having an inner surface surrounding the inner sheath distally to the distal end;', 'defining an annulus between the outer surface and the inner surface, the annulus having a vacuum connection at which a vacuum is applied to the annulus; and', 'having a substantially constant outer diameter over the portion to the distal end;, 'an outer sheath], 'providing a mechanical stiffener to at least a portion of a catheter shaft, the catheter shaft comprisingproviding a tool having a shape and a length sufficient to pass through the access lumen and past the distal end; andplacing the portion in an increased stiffened state by applying vacuum to the vacuum connection to create a stable base with at least a segment of the shaft within the anatomy that atraumatically resists reaction forces applied to the shaft by the tool.2. The method according to claim 1 , which further comprises placing the portion ...

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Номер записи: 68

21-01-2021 дата публикации

Ablation lesion quality

Номер: US20210015549A1

Автор: Ali Haghighi-Mood, Richard Jonathan Cohen

Принадлежит: Sirona Medical Technologies Inc

Improved ablation procedures and exemplary catheters for use with such procedures are provided. In one example, high quality homogenous lesions with well-defined borders can be created by introducing into a patient body a catheter that includes an electrode that is mounted on a distal end of the catheter, positioning the electrode to be in contact with tissue to be ablated such that at least 65 percent of an exposed distal surface area of the electrode is in contact with the tissue to be ablated, and applying electrical energy to the electrode sufficient to create an ablation lesion in the tissue.

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Номер записи: 69

28-01-2016 дата публикации

SYSTEM AND METHOD FOR CARDIAC ABLATION

Номер: US20160022375A1

Автор: BLAKE ROBERT, Kokones Scott, TICE Brock

Принадлежит:

A system for determining cardiac targets is provided. The system may include at least one processing device configured to carry out instructions to receive cardiac imaging data, segment the cardiac imaging data to identify at least two types of cardiac tissue, generate a cardiac model based on the identified tissue, simulate cardiac activity based on the generated cardiac model, and identify at least one cardiac target based on the simulation. A cardiac therapy system may be utilized to provide feedback to a user in order to guide a cardiac treatment device to a cardiac target. 1. A system for determining cardiac targets , the system comprising:a non-transitory computer readable medium comprising instructions;at least one processing device configured to carry out the instructions to:receive cardiac imaging data;segment the cardiac imaging data to identify at least two types of cardiac tissue;generate a cardiac model based on the identified tissue;simulate cardiac activity based on the generated cardiac model; andlocate at least one cardiac target based on the simulation.2. The system of claim 1 , wherein the at least one processing device is further configured to carry out the instructions to:display the cardiac target location on a cardiac mapping system.3. The system of claim 1 , wherein the at least one processing device is further configured to carry out the instructions to:guide a treatment catheter to the cardiac target location.4. The system of claim 1 , wherein the cardiac imaging data is obtained from at least one of magnetic resonance imaging claim 1 , computed tomography claim 1 , echocardiogram claim 1 , and positron emission tomography.5. The system of claim 1 , wherein segmenting the cardiac imaging data includes identifying at least two of scar tissue claim 1 , border tissue claim 1 , and healthy tissue.6. The system of claim 1 , wherein generating the cardiac model includes generating a finite mesh.7. The system of claim 1 , wherein simulating ...

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Номер записи: 70

25-01-2018 дата публикации

METHODS AND SYSTEM FOR IMAGE GUIDED CELL ABLATION WITH MICROSCOPIC RESOLUTION

Номер: US20180021090A1

Автор: Ferrer Jorge, Lee W. David

Принадлежит: Lumicell, Inc.

The invention provides systems and method for the removal of diseased cells during surgery 1. An in vivo method of treating a subject with a tumor comprising:(a) administering a composition comprising a molecular imaging probe to the subject, wherein the imaging probe labels at least one of tumor cells and tumor associated cells;(b) permitting the molecular imaging probe to clear preferentially from healthy tissue leaving the at least one of tumor cells and tumor associated cells labeled;(c) performing initial resection surgery to remove tumor cells from the subject thereby creating a resection bed;(d) directing light towards the resection bed;(e) obtaining an in situ fluorescence image of the resection bed using an imaging system;(f) detecting the labeled tumor cells or the labeled tumor associated cells, if present in the resection bed, using the fluorescence image; and(g) if labeled tumor cells or labeled tumor associated cells are detected in (f), performing further resection surgery to remove the labeled tumor cells or labeled tumor associated inflammation cells.2. The method of claim 1 , wherein detecting the labeled tumor cells or the labeled tumor associated cells claim 1 , if present in the resection bed claim 1 , comprises detecting the labeled tumor associated cells claim 1 , if present in the resection bed.3. The method of claim 1 , wherein detecting the labeled tumor cells or the labeled tumor associated cells claim 1 , if present in the resection bed claim 1 , comprises detecting both the labeled tumor cells and the labeled tumor associated cells claim 1 , if present in the resection bed.4. The method of claim 1 , wherein the tumor associated cells include at least one of tumor associated inflammation cells and tumor associated macrophages.5. The method of claim 1 , wherein the light has a wavelength between 100 nm and 2500 nm.6. The method of claim 1 , wherein the molecular imaging probe is a clearance differential probe including a fluorescent label ...

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Номер записи: 71

24-01-2019 дата публикации

CATHETER SYSTEM AND METHODS OF MEDICAL USES OF SAME, INCLUDING DIAGNOSTIC AND TREATMENT USES FOR THE HEART

Номер: US20190021673A1

Автор: Beatty Graydon E., CORVI Timothy J., FLAHERTY J. Christopher, Julian Marcus Frederick, WERNETH Randell L.

Принадлежит:

The present invention includes systems, devices and methods for treating and/or diagnosing a heart arrhythmia, such as atrial fibrillation. Specifically, the present invention provides a system including a diagnostic catheter and an ablation catheter. The diagnostic catheter includes a shaft, multiple dipole mapping electrodes and multiple ultrasound transducers. The ablation catheter is slidingly received by the diagnostic catheter shaft. 1. (canceled)2. A catheter system , comprising: an elongate shaft comprising a distal end;', 'an expandable assembly mounted to the elongate shaft, the expandable assembly comprising multiple splines and configured to transition from a compacted state to an expanded state;', 'a plurality of electrodes coupled to the multiple splines of the expandable assembly, each electrode configured to emit electric signals and record electric signals; and', 'a plurality of ultrasound transducers coupled to the multiple splines of the expandable assembly;, 'a diagnostic catheter comprisinga distance measurement assembly configured to drive the plurality of ultrasound transducers to produce anatomical geometry data, and including data representing a distance between each ultrasound transducer of the plurality of ultrasound transducers and a tissue surface orthogonal to each ultrasound transducer; and measure spacing between two or more of the electrodes based on the recorded electric signals and to determine a geometric configuration of one or more of the multiple splines based on the measured electrode spacing; and', 'create a three-dimensional anatomical map based on the produced anatomical geometry data, create electrical information based on the recorded electric signals, and display the electrical information in relation to the three-dimensional anatomical map,', the electrical information is further based on the determined geometric configuration of the one or more of the multiple splines, and/or', 'the anatomical geometry data is based on ...

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Номер записи: 72

23-01-2020 дата публикации

DEVICES AND METHODS FOR MAPPING CARDIAC TISSUE

Номер: US20200022573A1

Автор: Hitchcock Robert W., Huang Chao, Knighton Nathan J., Marrouche Nassir F., Sachse Frank B.

Принадлежит:

The present disclosure relates to systems and methods for generating three-dimensional tissue maps, and particularly fibrosis maps of cardiac tissue. An intravascular device includes an elongated member and a distal tip. An imaging assembly is integrated with the elongated member to enable imaging of the microstructure of tissue near the distal tip. One or more navigation electrodes are positioned at or near the distal tip. Electrical mapping and/or ablation assemblies may also be integrated with the device. Images may be characterized according to a level of fibrosis and, using the corresponding determined locations of the images, a three-dimensional map showing areas of differential fibrosis may be generated. Electrical mapping data may also be integrated with the fibrosis map to generate a composite fibrosis and voltage map. 1. An intravascular device configured for in-situ imaging , at a microstructure level , of tissue within a patient's body , the device comprising:an elongated member having a proximal end and a distal end;a distal tip disposed at or near a distal end of the elongated member and being configured for delivery to a targeted tissue within a patient's body;an imaging assembly configured to provide microstructure imaging of targeted tissue, the imaging assembly including an optical housing disposed at the distal tip and configured to house one or more imaging components to enable imaging of tissue at or near the distal tip; anda localization assembly configured to provide location information of the distal tip within a three-dimensional anatomical working space, the localization assembly including one or more localization components disposed at or near the distal tip.2. The device of claim 1 , wherein the localization assembly includes one or more localization electrodes disposed at the distal tip claim 1 , the one or more localization electrodes being configured to provide positional data relative to a reference electrode.3. The device of claim 1 ...

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Номер записи: 73

23-01-2020 дата публикации

Systems and Methods for Performing Electrophysiology (EP) Signal Processing

Номер: US20200022591A1

Автор: Asirvatham Samuel J., DRAKULIC Budimir S., FAKHAR Sina, Foxall Thomas G., VLAJINIC Branislav

Принадлежит:

Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The embodiment further includes a communications interface communicatively coupled to a remote device, and a processor, coupled to the ECG circuit board, the plurality of IC circuit boards, and the communications interface. The processor is configured to receive, via the communications interface, feedback from the remote device. The processor is further configured to control, via the communication interface, the remote device based on the ECG signal, the IC signals, or the feedback from the remote device. 1. A system for performing electrophysiology (EP) signal processing , comprising:an electrocardiogram (ECG) circuit board configured to receive an ECG signal;a plurality of intracardiac (IC) circuit boards, each configured to receive a corresponding IC signal;a communications interface coupled to a remote device; and receive, via the communications interface, feedback from the remote device; and', 'control, via the communication interface, the remote device based on the ECG signal, the IC signals, or the feedback from the remote device., 'a processor, coupled to the ECG circuit board, the plurality of IC circuit boards, and the communications interface, configured to2. The system of claim 1 , wherein the remote device is selected from the group consisting of an ultrasound machine claim 1 , a radio frequency (RF) generator claim 1 , a stimulator claim 1 , a three-dimensional imaging device claim 1 , an intra-cardiac echocardiography (ICE) machine claim 1 , a fluoroscopy machine claim 1 , and a defibrillator.3. The system of claim 1 , wherein the communications interface is coupled to the remote device using ...

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Номер записи: 74

23-01-2020 дата публикации

Estimation of effectiveness of ablation adjacency

Номер: US20200022649A1

Автор: Eli Dichterman, Haim RODRIGUEZ, Shlomo Ben-Haim, Yitzhack Schwartz, Yizhaq SHMAYAHU, Zalman Ibragimov

Принадлежит: Navix International Ltd

Methods for estimating of the effectiveness of catheter ablation procedures to form lesions, and particular lesions which together form an ablation segment of an ablation line. Lesion effectiveness parameters are received, and effectiveness, optionally the joint effectiveness, of corresponding ablations (optionally planned, current, and/or already performed) is estimated. In some embodiments, estimating is based on use by computer circuitry of an estimator constructed based on observed associations between previously analyzed lesion effectiveness parameters, and observed lesion effectiveness. Additionally or alternatively, estimators may be constructed based on analytic functions. The estimator is used by application to the received lesion effectiveness parameters.

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Номер записи: 75

10-02-2022 дата публикации

Apparatus for treating cardiac arrhythmias utilizing a machine learning algorithm to optimize an ablation index calculation

Номер: US20220044787A1

Автор: Ana KAUFMAN, Shiran Eliyahu, Shmuel Auerbach

Принадлежит: Biosense Webster Israel Ltd

A method is provided. The method includes receiving, by an optimization engine, inputs from previous ablation procedures. The method also includes training, by the optimization engine, a machine learning algorithm of the optimization engine to learn scenarios for the previous ablation procedures. The method also includes generating, by the optimization engine, ablation indices for the scenarios.

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Номер записи: 76

04-02-2016 дата публикации

Large surface area temperature sensing device

Номер: US20160029897A1

Автор: Shawn P. Fojtik

Принадлежит: Circa Scientific Inc

A temperature probe for monitoring temperatures of a surface of a tissue or organ within the body of a subject includes a section with a substantially two-dimensional arrangement and a plurality of temperature sensors positioned across an area defined by the substantially two-dimensional arrangement. Such an apparatus may be used in conjunction with procedures in which thermal techniques are used to diagnose a disease state or treat diseased tissue. Specifically, a temperature probe may be used to monitor temperatures across an area of a surface of a tissue or organ located close to the treated tissue to prevent subjection of the monitored tissue or organ to potentially damaging temperatures.

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Номер записи: 77

02-02-2017 дата публикации

DUAL BASKET CATHETER

Номер: US20170027638A1

Автор: Solis Mario A.

Принадлежит:

This disclosure is directed to a catheter having a basket-shaped electrode assembly at the distal end of the catheter body formed from a plurality of spines with electrodes. Each spine is deflectable outwards into an expanded configuration, so that the basket-shaped electrode assembly has a proximal basket area and a distal basket area with different equatorial diameters. 1. A catheter comprising an elongated catheter body having proximal and distal ends and at least one lumen therethrough and a basket-shaped electrode assembly at the distal end of the catheter body , the basket-shaped electrode assembly comprising a plurality of spines connected at their proximal and distal ends , each spine comprising at least one electrode and configured to deflect outwards into an expanded configuration , wherein the basket-shaped electrode assembly has a proximal basket area and a distal basket area having different equatorial diameters when the basket-shaped electrode assembly is in the expanded configuration.2. The catheter of claim 1 , wherein the distal basket area has a relatively smaller equatorial diameter than the proximal basket area.3. The catheter of claim 1 , wherein each spine has a proximal convex portion corresponding to the proximal basket area claim 1 , a distal convex portion corresponding to the distal basket area and an intermediate concave portion separating the proximal convex portion and the distal convex portion.4. The catheter of claim 1 , wherein each spine comprises at least one sensing electrode.5. The catheter of claim 1 , wherein each spine comprises at least one ablation electrode.6. The catheter of claim 1 , wherein each spine comprises a proximal sensing electrode claim 1 , a distal sensing electrode and an ablation electrode positioned between the proximal sensing electrode and the distal sensing electrode.7. The catheter of claim 6 , wherein the proximal sensing electrode claim 6 , the distal sensing electrode and the ablation electrode are ...

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Номер записи: 78

02-02-2017 дата публикации

EFFICIENT TREATMENT OF ATRIAL FIBRILLATION USING THREE-DIMENSIONAL ELECTRICAL POTENTIAL MODEL

Номер: US20170027649A1

Автор: Kamen Ali, Kiraly Atilla Peter, Mansi Tommaso

Принадлежит:

A method for guiding electrophysiology (EP) intervention using a patient-specific electrophysiology model includes acquiring a medical image of a patient subject (S). Sparse EP signals are acquired over an anatomy using the medical image for guidance (S). The sparse EP signals are interpolated using a patient specific computational electrophysiology model and a three-dimensional model of EP dynamics is generated therefrom (S). A rendering of the three-dimensional model is displayed. Candidate intervention sites are received, effects on the EP dynamics resulting from intervention at the candidate intervention sites is simulated using the model, and a rendering of the model showing the simulated effects is displayed (S). 1. A method for guiding electrophysiology (EP) intervention using a patient-specific electrophysiology model , comprising:acquiring a medical image of a region of interest of a patient subject;acquiring a set of sparse EP signals over an anatomy of the region of interest using the acquired medical image for guidance;interpolating the acquired set of sparse EP signals using a patient specific computational electrophysiology model to generate an enlarged set of EP signals, the enlarged set of EP signals including more EP signals than the set of sparse EP signals;generating a three-dimensional model of EP dynamics within the region of interest using the enlarged set of EP signals;displaying a rendering of the generated three-dimensional model to a user;receiving, from the user, a set of one or more candidate intervention sites;simulating effects on the EP dynamics within the region of interest resulting from intervention at the set of one or more candidate intervention sites using the generated three-dimensional model; anddisplaying a rendering of the three-dimensional model showing the simulated effects to the user.2. The method of claim 1 , further comprising: receiving claim 1 , from the user claim 1 , an indication of whether the simulated effects ...

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Номер записи: 79

04-02-2016 дата публикации

Device for intravascular therapy and/or diagnosis

Номер: US20160030108A1

Автор: Fermin Armando LUPOTTI

Принадлежит: St Jude Medical Atrial Fibrillation Division Inc

An elongate medical device may include an elongate body having a proximal end portion and a distal end portion and defining a longitudinal axis extending from the proximal end portion to the distal end portion. The elongate medical device may further include a basket assembly coupled to the distal end portion comprising a plurality of ablation elements, each of the ablation elements configured to ablate a respective target, the basket assembly disposed on a radial exterior of the elongate body. The elongate medical device may further include an imaging transmitter disposed radially-inward of the ablation elements and configured to project imaging energy towards at least one of the respective targets.

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Номер записи: 80

01-02-2018 дата публикации

BASKET CATHETER WITH IMPROVED SPINE FLEXIBILITY

Номер: US20180028084A1

Автор: Solis Mario A., Tran Paul, Williams Stuart

Принадлежит:

A catheter with basket-shaped electrode assembly with spines configured for hyper-flexing in a predetermined, predictable manner when a compressive force acts on the assembly from either its distal end or its proximal end. At least one spine has at least one region of greater (or hyper) flexibility that allows the electrode assembly to deform, for example, compress, for absorbing and dampening excessive force that may otherwise cause damage or injury to tissue wall in contact with the assembly, without compromising the structure and stiffness of the remaining regions of the spine, including its distal and proximal regions. The one or more regions of greater flexibility in the spine allow the spine to flex into a generally V-shape configuration or a generally U-shape configuration. 1. A catheter comprising:an elongated catheter body having proximal and distal ends and at least one lumen therethrough; and an expander that is longitudinally moveable relative to the catheter body; and', 'a plurality of spines having proximal and distal ends surrounding the expander, at least one spine having an equatorial region of greater flexibility and proximal and distal regions of lesser flexibility, the basket-shaped electrode assembly being moveable by longitudinal movement of the expander between a collapsed configuration, an expanded configuration in which the spines bow radially outward relative to the catheter body to form a first expanded shape, and a hyper-expanded configuration in which the spines bend at the equatorial region of greater flexibility to thereby deform the first expanded shape, shorten a length of the basket-shaped electrode assembly and assume a V shape with an acute bend in the equatorial region of greater flexibility., 'a basket-shaped electrode assembly at the distal end of the catheter body, the basket-shaped electrode assembly having proximal and distal ends and comprising2. The catheter of claim 1 , wherein the at least one spine has a width dimension ...

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Номер записи: 81

01-02-2018 дата публикации

CRYOGENIC BALLOON DEVICE WITH ELECTROPORATION TREATMENT REGION

Номер: US20180028252A1

Автор: LALONDE Jean-Pierre

Принадлежит:

An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment. 1. A method of treating tissue , the method comprising: an elongate catheter body having a proximal portion and a distal portion;', 'an expandable first treatment region coupled to the distal portion of the elongate catheter body; and', 'a second treatment region coupled to the distal portion of the catheter body at a location that is distal to the cryogenic treatment region and defines an outer surface and a distal tip of the medical device;, 'positining a medical device proximate a first tissue area, the medical device includingactivating the expandable first treatment region to create a first treatment pattern in the first tissue area;deactivating the expandable first treatment region;repositioning the medical device such that the second treatment region is proximate a second tissue area; andactivating the second treatment region to treat a second treatment pattern in the second tissue area, the second treatment pattern being different than the first treatment pattern.2. The method of claim 1 , wherein the second treatment region is at least one of a radiofrequency treatment region and an electroporation treatment region.3. The method of claim 1 , wherein the second treatment region includes at least one electrode.4. The method of claim 3 , wherein the second treatment region is an electroporation treatment region.5. The method of claim 4 , further comprising a power source in communication with the at least one electrode and being configured to transmit electrical pulses claim 4 , activation of the second treatment ...

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Номер записи: 82

24-04-2014 дата публикации

Catheter system

Номер: US20140114307A1

Автор: Marius J. Postma, Saar Moisa

Принадлежит: Kardium Inc

A manipulable portion of a catheter system advances out of a lumen of a catheter sheath at a distal end of a shaft, which is also within the lumen of the catheter sheath. The catheter system causes different advancement and retraction trajectories of a manipulable portion out of and into the lumen based at least upon different relative movements between the catheter sheath and the shaft. A projection and a corresponding receiver may be used to control relative positioning of the catheter sheath and the shaft, as well as to control positioning of the manipulable portion. The catheter system may control metering rates of a control element coupled to the manipulable portion during advancement and retraction of the manipulable portion. A control element of the catheter system has varying amounts of length outside a distal end of the catheter sheath during advancement and retraction of the manipulable portion.

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Номер записи: 83

17-02-2022 дата публикации

Esophageal Probes and Methods

Номер: US20220047284A1

Автор: Mehdi Razavi, Robert Paisley

Принадлежит: Baylor College of Medicine, TEXAS HEART INSTITUTE

Methods for collapsing a tubular organ, such as the esophagus, involve inserting a device into the tubular organ, at least partially sealing off a section of the tubular organ, and drawing in the wall of the tubular organ by application of suction. The devices may be used to move the wall of the tubular organ away from an area undergoing treatment or therapy, such as to minimize damage to the tubular organ by application of radiofrequency energy or to limit temperature increase of the tubular organ.

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Номер записи: 84

17-02-2022 дата публикации

Systems and methods for treating tissue with pulsed field ablation

Номер: US20220047319A1

Автор: Gerald Floyd Cummings, Shane Fredrick Miller-Tait

Принадлежит: Kardium Inc

Pulsed field ablation systems are disclosed, some of which may include an output pulse generation circuit and a high voltage pulse generation circuit electrically connected to the output pulse generation circuit. The high voltage pulse generation circuit may be configured to deliver a high voltage pulse set to the output pulse generation circuit. The output pulse generation circuit may be configured to generate an output pulse set at least in response to the high voltage pulse set. The output pulse set may be deliverable to a set of selectable electrodes and may be configured to cause pulsed field ablation of tissue. Each pulse in the output pulse set may have a rise time that is shorter than a rise time of at least one high voltage pulse in the high voltage pulse set.

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Номер записи: 85

17-02-2022 дата публикации

SYSTEM OF MEDICAL DEVICES AND METHOD FOR PERICARDIAL PUNCTURE

Номер: US20220047324A1

Автор: Abou-Marie Rund, Fok Kai-Lon, Gravett Matthew, MILLER Brock

Принадлежит:

A system for pericardial puncture includes a medical device having an elongate shaft extending between a proximal end and a distal end, and having a distally facing electrode at the distal end of the shaft. An impedance meter is electrically connectable with the electrode for measuring an impedance associated with the electrode. A display is provided for displaying an indication of a position of the electrode. The indication of the position is based on of the impedance. 1. A system for pericardial puncture comprising:a medical device having an elongate shaft extending between a proximal end and a distal end, and having an electrode at the distal end of the shaft;an impedance meter electrically connectable with the electrode for measuring an impedance associated with the electrode; anda display for displaying an indication of a position of the medical device, wherein the indication of the position is based on of the impedance.2. The system of claim 1 , wherein the indication of the position of the medical device is an indication of whether the medical is in contact with a target tissue.3. The system of claim 1 , wherein the medical device is an introducer and the shaft has a lumen extending therethrough from the proximal end to the distal end.4. The system of claim 3 , wherein;the shaft comprises a metallic tube and an electrically insulative sheathing on the tube; andthe electrode comprises an electrically exposed section of the tube.5. The system of claim 3 , wherein the shaft comprises an electrical conductor extending proximally from the electrode for electrically connecting the electrode to the impedance meter.6. The system of claim 3 , further comprising a puncture device advanceable through the lumen from the proximal end to the distal end.7. The system of claim 6 , whereinthe puncture device is a radiofrequency puncture device; andthe system further comprises a radiofrequency generator electrically connectable with the electrode for delivering radiofrequency ...

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Номер записи: 86

17-02-2022 дата публикации

Applying Bipolar Ablation Energy Between Shorted Electrode Groups

Номер: US20220047326A1

Автор: Andres Claudio Altmann, Assaf Govari

Принадлежит: Biosense Webster Israel Ltd

A system includes a catheter, a switching assembly, and a processor. The catheter including an expandable frame, which is coupled to a distal end of the catheter, and multiple electrodes, which are disposed on the expandable frame in a radial geometry. The switching assembly is electrically connected to the catheter, and is configured to electrically short between selected ones of the electrodes. The processor is configured, for first and second disjoint groups of the electrodes, to control the switching assembly to electrically short the electrodes within each of the first and second groups, for applying one or more bipolar ablation energy between the first and second groups when the electrodes are placed in contact with a target tissue of the organ.

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Номер записи: 87

17-02-2022 дата публикации

APPARATUS AND METHOD FOR INTRA-CARDIAC MAPPING AND ABLATION

Номер: US20220047328A1

Автор: Gelbart Daniel, Lichtenstein Samuel Victor

Принадлежит:

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a Maze procedure. The location of the ports and valves is based on using the convective cooling effect of the blood flow. The mapping can be performed by a catheter-deployed expandable net or a scanning catheter. The same net or catheter can also perform the ablation procedure. 1. (canceled)2. A medical system comprising:a catheter including a meshed structure, the meshed structure including a plurality of vertices, each vertex of at least a first vertex of the plurality of vertices being where four segments of the meshed structure converge, the meshed structure comprising a proximal end and a distal end, the meshed structure configured to be delivered to a bodily organ with the distal end ahead of the proximal end, and the first vertex located on the meshed structure between the proximal end and the distal end of the meshed structure; anda control computer operatively coupled via a wire connection configuration to the meshed structure and configured, for at least the first vertex of the plurality of vertices, to cause delivery of tissue ablative energy to tissue at least proximate a first segment of the four segments of the meshed structure converging at the first vertex independently of causing delivery of tissue ablative energy to tissue at least proximate a second segment of the four segments of the meshed structure converging at the first vertex.3. The medical system of claim 2 , wherein each segment of the four segments of the meshed structure converging at the first vertex comprises an external metallic portion extending along at least part of the segment claim 2 , the external metallic portion configured to deliver tissue ablative energy claim 2 , and the external metallic portion configured to be ...

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Номер записи: 88

31-01-2019 дата публикации

SYSTEMS AND METHODS FOR SELECTING, ACTIVATING, OR SELECTING AND ACTIVATING TRANSDUCERS

Номер: US20190029608A1

Автор: Moisa Saar, WEBER Michael Hermann

Принадлежит:

A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation. 1. A medical device system comprising:a data processing device system;an input-output device system communicatively connected to the data processing device system; anda memory device system communicatively connected to the data processing device system and storing a program executable by the data processing device system, the program comprising:communication instructions configured to cause the data processing device system to communicate, via the input-output device system, with an electrode-based device system comprising a structure and a plurality of electrodes arrangeable in a three dimensional distribution on the structure, the structure and the plurality of electrodes locatable within a bodily cavity;first display instructions configured to cause the input-output device system to display information regarding at least the electrode-based device system, the displayed information including a graphical representation of at least a portion of the electrode-based device system, the graphical ...

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Номер записи: 89

31-01-2019 дата публикации

SYSTEMS AND METHODS FOR SELECTING, ACTIVATING, OR SELECTING AND ACTIVATING TRANSDUCERS

Номер: US20190029609A1

Автор: Moisa Saar, WEBER Michael Hermann

Принадлежит:

A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation. 1. A medical device system comprising:a data processing device system;an input-output device system communicatively connected to the data processing device system; anda memory device system communicatively connected to the data processing device system and storing a program executable by the data processing device system, the program comprising:communication instructions configured to cause the data processing device system to communicate, via the input-output device system, with an electrode-based device system comprising a structure and a plurality of electrodes arrangeable in a three dimensional distribution on the structure, the structure and the plurality of electrodes locatable within a bodily cavity, and the structure including a first domed portion and a part other than the first domed portion;first display instructions configured to cause the input-output device system to display information regarding at least the electrode-based device system, the displayed information including a ...

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Номер записи: 90

31-01-2019 дата публикации

Directional balloon transseptal insertion device for medical procedures

Номер: US20190029750A1

Автор: Brijeshwar S. MAINI

Принадлежит: East End Medical LLC

A transseptal insertion device suitable for facilitating precise and safe transseptal puncture of a cardiac interatrial septum includes a sheath that defines a lumen and has a distal end that is closest to the cardiac interatrial septum of a patient and a proximal end that is external to the patent, a balloon that is connected to the distal end of the sheath, in which the balloon, when inflated, overhangs and extends past the distal end of the sheath, preventing accidental puncturing of the cardiac interatrial septum and stabilizing the transseptal insertion device against fossa ovalis of the cardiac interatrial septum, and a dilator that is positioned within the at least one lumen. The dilator has a distal end and is designed to and is capable of precisely puncturing the cardiac interatrial septum without the use of a needle or other sharp instrument.

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Номер записи: 91

31-01-2019 дата публикации

ELECTRODE ASSEMBLY WITH THERMAL SHUNT MEMBER

Номер: US20190029752A1

Автор: Koblish Josef Vincent, Panescu Dorin, Schultheis Eric Andrew

Принадлежит:

According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member. 1. (canceled)2. An electrode assembly for an ablation catheter with thermal shunting , the electrode assembly comprising:a proximal electrode portion;a distal electrode portion;a filtering element electrically coupling the proximal electrode portion to the distal electrode portion and configured to present a low impedance at a frequency used for delivering ablative energy via the proximal and distal electrode portions; andat least one thermal shunt member in thermal communication with the proximal electrode portion and the distal electrode portion to selectively remove heat from at least one of the electrode assembly and tissue being treated by the electrode assembly when the electrode assembly is activated;wherein the at least one thermal shunt member extends at least partially through an interior of the electrode assembly to transfer heat from the electrode assembly during use;wherein the at least one thermal shunt member is configured to receive at least one fluid conduit extending at least partially through an interior of the at least one thermal shunt member, wherein the at least one thermal shunt member is in thermal communication with the at least one fluid conduit; andwherein the at least one fluid conduit is configured to place the electrode assembly in fluid ...

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Номер записи: 92

31-01-2019 дата публикации

METHODS OF REMOVING HEAT FROM AN ELECTRODE USING THERMAL SHUNTING

Номер: US20190029753A1

Автор: Koblish Josef Vincent, Panescu Dorin, Schultheis Eric Andrew

Принадлежит:

According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member. 1. (canceled)2. A method of heat removal from an electrode assembly during a tissue treatment procedure , the method comprising:delivering energy to an electrode assembly of an ablation system, the ablation system comprising a catheter comprising a distal end, the electrode assembly positioned along the distal end of the catheter;wherein the catheter of the ablation system comprises at least one thermal shunt member along its distal end,wherein the at least one thermal shunt member extends at least partially through an interior of the electrode assembly; andwherein the catheter further comprises at least one fluid passage extending at least partially through the interior of the electrode assembly and an interior of the at least one thermal shunt member;delivering a fluid through the at least one fluid passage; andtransferring heat from the electrode assembly to the fluid via the at least one thermal shunt member to reduce the likelihood of localized hot spots along the distal end of the catheter.3. The method of claim 2 ,{'sup': '2', 'wherein the at least one thermal shunt member is configured to transfer heat while not retaining heat, and wherein the at least one thermal shunt member comprises a thermal diffusivity greater than 1.5 cm/sec;'}wherein the electrode assembly ...

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Номер записи: 93

31-01-2019 дата публикации

Expandable elements for delivery of electric fields

Номер: US20190030328A1

Автор: Brian T. HOWARD, Mark T. Stewart

Принадлежит: MEDTRONIC INC

A method, system, and device for electroporation. A system may include a medical device with a plurality of electrodes borne on an expandable element and an energy generator in communication with the electrodes. The energy generator may have processing circuitry configured to selectively deliver electroporation energy to at least one of the electrodes. The processing circuitry may determine whether an alert condition is present and, if so, cease the delivery of electroporation energy to one or more electrodes identified as the cause of the alert condition and/or prevent the delivery of electroporation energy to the one or more electrodes identified as the cause of the alert condition. The energy generator may also be configured to deliver electroporation energy in a sequence of a plurality of energy delivery patterns to enhance lesion formation.

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Номер записи: 94

30-01-2020 дата публикации

Systems and methods for activating transducers

Номер: US20200030019A1

Автор: Daniel M. Reinders, Daniel R. Weinkam

Принадлежит: Kardium Inc

In some embodiments, a plurality of transducers of a transducer-based device may be selected for activation. A first pair of subsets of the selected transducers may be identified for initial activation, each subset of the first pair being activated with a different phase angle range than the other. No transducer in one subset is sufficiently close to a transducer in the other subset to cause a confluence of ablated tissue regions therebetween. The first pair of subsets may be activated simultaneously or concurrently. Upon activation or a conclusion thereof of the pair of subsets of the selected transducers, one or more subsequent pairs of subsets of the selected transducers may be activated iteratively on a pair-by-pair basis, until all of the selected transducers have achieved desired activation results, according to some embodiments. Each subsequent pair may include the same or similar characteristics as the first pair.

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Номер записи: 95

30-01-2020 дата публикации

Method And Device For Interventricular Septal Ablation

Номер: US20200030022A1

Автор: Hu Rui, LIU Liwen

Принадлежит: Fourth Military Medical University

A method for treating hypertrophic cardiomyopathy (HCM) utilizes an RF ablation electrode needle system that has an RF ablation generator, and an electrode needle. The electrode needle is introduced to puncture within myocardium and to reach the hypertrophic area of the interventricular septum. The RF ablation generator is then turned on to implement single-point or multi-point ablation on the hypertrophic area of the interventricular septum, and then the RF electrode needle is withdrawn from the patient. 1. A method for treating hypertrophic cardiomyopathy (HCM) , comprising the steps of:providing an RF ablation electrode needle system comprising an RF ablation generator, and an electrode needle;introducing the electrode needle to puncture within myocardium and to reach the hypertrophic area of the interventricular septum;turning on the RF ablation generator to implement single-point or multi-point ablation on the hypertrophic area of the interventricular septum; andwithdrawing the RF electrode needle from the patient.2. The method of claim 1 , wherein the electrode needle is introduced to pierce through epicardium and then advance along an intramyocardial pathway until reach the hypertrophic area of the interventricular septum.3. The method of claim 1 , wherein the electrode needle reaches the hypertrophic area of the interventricular septum along a long axis of the interventricular septum.4. The method of claim 1 , wherein the electrode needle reaches the hypertrophic area of the interventricular septum a short axis of the interventricular septum.5. The method of claim 1 , further comprising a step of using an imaging equipment for displaying the myocardium.6. The method of claim 5 , wherein the imaging equipment is an ultrasound monitoring device or Magnetic Resonance Imaging device.7. The method of claim 3 , wherein the electrode needle is introduced to puncture a connection part of apex and septum claim 3 , and then enter into the interventricular septum and ...

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Номер записи: 96

17-02-2022 дата публикации

CO-REGISTRATION OF CARDIAC IMAGES

Номер: US20220051421A1

Автор: Dichterman Eli, RODRIGUEZ Haim, Schwartz Yitzhack

Принадлежит:

Systems, devices, and methods for co-registering electro-anatomical images are provided. In one embodiment of the present disclosure, treatment locations are displayed to the physician on an image of the remodeled heart by co-registering first and second electro-anatomical images based on: (1) a first electro-anatomical image of an anatomy, (2) treatment location data indicating treatment locations with respect to the first electro-anatomical image, (3) a second electro-anatomical image of the anatomy after the anatomy has remodeled, and (4) a non-rigid transformation that transforms the first electro-anatomical image to the second electro-anatomical image of the remodeled anatomy. The non-rigid transformation is applied to the treatment location data to map the treatment locations to the second electro-anatomical image of the remodeled anatomy. 1. A system for co-registering electro-anatomical images , comprising:a user display; and{'claim-text': ['receive a first electro-anatomical image of an anatomy, the first electro-anatomical image generated based on electro-anatomical data obtained using two or more electrodes positioned on a catheter;', 'receive treatment location data indicating treatment locations with respect to the first electro-anatomical image, the treatment location data based on the electro-anatomical data obtained using the two or more electrodes positioned on the catheter;', 'receive a second electro-anatomical image of the anatomy after the anatomy has remodeled;', 'determine a non-rigid transformation that transforms the first electro-anatomical image to the second electro-anatomical image of the remodeled anatomy;', 'apply the non-rigid transformation to the treatment location data to map the treatment locations to the second electro-anatomical image of the remodeled anatomy; and', 'display the treatment locations mapped to the second electro-anatomical image on the user display.'], '#text': 'a processor circuit in communication with the user ...

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Номер записи: 97

09-02-2017 дата публикации

FORCE SENSING CATHETERS HAVING SUPER-ELASTIC STRUCTURAL STRAIN SENSORS

Номер: US20170035358A1

Автор: Rankin Darrell L.

Принадлежит:

Various embodiments concern a system for measuring a force on a catheter. The catheter can comprise a proximal segment, a distal segment, and an intermediary segment comprising at least one strut. Each strut can extend from the proximal segment to the distal segment. Each strut can be formed from a super-elastic metal alloy material, such as nitinol. The plurality of struts can be configured to resiliently support the distal segment with respect to the proximal segment while permitting relative movement between the distal segment and the proximal segment. The system can comprise control circuitry configured to measure, for each of the plurality of struts, a change in an electrical property of the super-elastic metal alloy material of the strut when the distal segment moves relative to the proximal segment to determine a magnitude and direction of the force. 1. A system for measuring a force on a catheter , the system comprising: a proximal segment;', 'a distal segment; and', 'an intermediary segment comprising at least one strut, each strut extending from the proximal segment to the distal segment, each strut formed from a super-elastic metal alloy material, the at least one strut configured to resiliently support the distal segment with respect to the proximal segment while permitting relative movement between the distal segment and the proximal segment; and, 'a catheter comprisingcontrol circuitry configured to measure, for each of the at least one strut, a change in an electrical property of the super-elastic metal alloy material of the strut when the distal segment moves relative to the proximal segment.2. The system of claim 1 , wherein the control circuitry is configured to calculate a magnitude and a direction of the force based on the changes in the electrical property of the super-elastic metal alloy material of the at least one strut.3. The system of claim 2 , further comprising a display claim 2 , wherein the control circuitry is configured to graphically ...

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Номер записи: 98

09-02-2017 дата публикации

Contact determination apparatus

Номер: US20170035387A1

Автор: Caifeng Shan, Fei Zuo, Godefridus Antonius Harks, Harm Jan Willem Belt, Jaap Knoester, Szabolcs Deladi

Принадлежит: Koninklijke Philips NV

The invention relates to a contact determination apparatus for determining a degree of contact between a device ( 2 ) and a moving object ( 3 ), wherein the contact determination apparatus comprises a motion distribution providing unit for providing a motion distribution being indicative of motion in the surrounding of the device and a contact determination unit ( 14 ) for determining a degree of contact between the device and the object based on the provided motion distribution. Since the degree of contact between the device and the object is determined based on the provided motion distribution and not simply based on, for instance, a peak of an A-mode signal, the determination of the degree of contact can be less disturbed by artifacts like ring-down artifacts or by blood scattering, if the object is, for instance, tissue. This can lead to a more accurate determination of the degree of contact.

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Номер записи: 99

09-02-2017 дата публикации

CARDIAC PULSED FIELD ABLATION

Номер: US20170035499A1

Автор: FRAASCH Steven J., STEWART Mark T.

Принадлежит:

A method for ablating tissue by applying at least one pulse train of pulsed-field energy. The method includes delivering a pulse train of energy having a predetermined frequency to cardiac tissue, the pulse train including at least 60 pulses, an inter-phase delay between 0 μs and 5 μs, an inter-pulse delay of at least 5 μs, and a pulse width of 5 μs. 1. A method of ablating cardiac tissue , the method comprising: at least 60 pulses;', 'an inter-phase delay between 0 μs and 5 μs;', 'an inter-pulse delay of at least 5 μs; and', 'a pulse width of 5 μs., 'delivering a pulse train of energy having a predetermined frequency to cardiac tissue, the pulse train including2. The method of claim 1 , wherein the pulse train of energy has a voltage between 300V and 4000V and wherein the predetermined frequency is approximately 1 kHz.3. The method of claim 1 , wherein the inter-pulse delay is 800 μs.4. The method of claim 1 , wherein the pulse train of energy is initiated between 70 ms and 100 ms after onset of an R-wave.5. The method of claim 1 , wherein the pulse train of energy is gated to initiate the delivery of the pulse train radiofrequency energy at the end of an S-wave.6. The method of claim 1 , wherein the pulse train of energy may be delivered to a plurality of cardiac treatment sites claim 1 , the method further comprising:delivering the pulse train of energy four times at each of the plurality of treatment sites.7. The method of claim 1 , further including positioning a medical device proximate the cardiac tissue to be treated claim 1 , the medical device including a distal electrode array having a plurality of electrodes claim 1 , each electrode having a polarity that is different than each adjacent electrode claim 1 , and where the pulse train of energy is delivered from the distal electrode array.8. The method of claim 7 , wherein the pulse train of energy is delivered in bipolar mode.9. The method of claim 8 , wherein the pulse train of energy includes biphasic ...

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Номер записи: 100