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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 1976. Отображено 100.
03-05-2012 дата публикации

High-frequency electroporation for cancer therapy

Номер: US20120109122A1

The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative disorders are provided. In embodiments, the methods comprise the delivery of high-frequency bursts of bipolar pulses to achieve the desired modality of cell death. More specifically, embodiments of the invention relate to a device and method for destroying aberrant cells, including tumor tissues, using high-frequency, bipolar electrical pulses having a burst width on the order of microseconds and duration of single polarity on the microsecond to nanosecond scale. In embodiments, the methods rely on conventional electroporation with adjuvant drugs or irreversible electroporation to cause cell death in treated tumors. The invention can be used to treat solid tumors, such as brain tumors.

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21-06-2012 дата публикации

Systems and methods for automatically identifying and segmenting different tissue types in ultrasound images

Номер: US20120157842A1
Принадлежит: General Electric Co

A system for providing non-invasive ultrasound based treatment to a region of interest is provided. The system comprises an imaging unit for imaging one or more tissue types in the region of interest, an image processing unit that is configured to identify the one or more tissue types in the region of interest, an ultrasound transducer that is configured to focus an ultrasound beam to ablate at least a portion of the identified tissues, and a controller unit that controls a delivery of the ultrasound beam to the region of interest.

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20-09-2012 дата публикации

Radiation-Based Dermatological Devices and Methods

Номер: US20120239016A1
Принадлежит: Tria Beauty Inc

A self-contained, hand-held device for providing radiation-based dermatological treatments includes a device body configured to be handheld by a user; a laser device supported in the device body, the laser device including a laser beam source configured to emit laser radiation; an application end configured to be manually moved across the surface of the skin during a treatment session; and electronics configured to control the laser beam source to emit laser radiation toward the skin to provide a dermatological treatment; wherein the device includes no optics downstream of the laser source.

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08-11-2012 дата публикации

Devices and Methods for Radiation-Based Dermatological Treatments

Номер: US20120283710A1
Принадлежит: Tria Beauty Inc

A hand-held device for providing laser-based dermatological treatments includes a laser beam source supported in a device body, an automated scanning system, and control electronics. The automated scanning system is configured to receive an input beam generated by the laser beam source and scan the input beam to provide a series of output beams for delivery to the skin via an application end of the device to form a pattern of treatment spots on the skin. The application end is configured for movement across the skin during a treatment session. The control electronics control the laser beam source and/or the automated scanning system to deliver the scanned output beams to the skin at a radiation intensity sufficient to provide an effective dermatological treatment, and wherein the scanned output beams delivered from the application end of the device meet the Class 1M or better eye safety classification per the IEC 60825-1.

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08-11-2012 дата публикации

Devices and Methods for Radiation-Based Dermatological Treatments

Номер: US20120283712A1
Принадлежит: Tria Beauty Inc

A hand-held device for providing a dermatological treatment by scanning a laser beam to form a pattern of treatment spots on the skin includes a laser source that generates an input beam, an automated scanning system, and a treatment spot control system. The automated scanning system includes a rotating multi-sector scanning element configured to repeatedly scan the input beam, each scan providing an array of output beams corresponding to the multiple sectors of the scanning element and forming a scanned row of treatment spots on the skin. The scanning element is configured such that each sector provides a constant-angular-direction output beam as that sector rotates through the input beam. The treatment spots of each scanned row are spaced apart from each other by areas of non-irradiated skin. The treatment spot control system provides a distance between adjacent rows of treatment spots in a direction of manual movement of the device.

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11-04-2013 дата публикации

Methods and systems for detection and thermal treatment of lower urinary tract conditions

Номер: US20130090640A1

The invention is directed to a method for treating a urinary system. The method includes positioning one or more treatment units with respect to an organ wall. The one or more treatment units may be configured to deliver thermal energy. The method further includes delivering energy through the one or more treatment units to heat tissue of the organ wall.

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25-04-2013 дата публикации

Litz wire battery powered device

Номер: US20130103023A1
Принадлежит: Ethicon Endo Surgery Inc

A medical instrument is disclosed. The medical instrument includes a housing and a handle for gripping by a user, an end effector coupled to the handle and having at least one electrical contact, a battery, and a radio frequency (RF) generation circuit coupled to and operated by the battery. The RF generation circuit is operable to generate an RF drive signal and to provide the RF drive signal to the at least one electrical contact, wherein the RF generation circuit is supported by the housing. The RF generation circuit includes a resonant circuit that includes at least one inductive element constructed of litz wire.

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16-05-2013 дата публикации

Battery shut-off algorithm in a battery powered device

Номер: US20130123776A1
Принадлежит: Ethicon Endo Surgery Inc

A medical instrument is disclosed. The medical instrument includes at least one electrical contact, a battery, a radio frequency (RF) generation circuit coupled to and operated by the battery and operable to generate an RF drive signal and to provide the RF drive signal to the at least one electrical contact, and a battery discharge circuit coupled to the battery. A processor is coupled to the battery discharge circuit and a memory is coupled to the processor. The memory stores machine executable instructions that when executed cause the processor to monitor activation of the RF generation circuit and disable the RF generation circuit when the RF drive signal is fired a predetermined number of times. The medical instrument may include an activation switch and/or a disposal switch supported by the housing.

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20-06-2013 дата публикации

Self operated esthetic device with a substrate

Номер: US20130158634A1
Принадлежит: VENUS CONCEPT LTD

The present invention provides a self-operated device for treating a skin of a patient, comprising: a. a substrate having a first side and a second side; b. a plurality of RF electrodes arranged in said substrate, said RF electrodes are configured to emit RF radiation from said first side to the surface of said skin; c. at least one RF generator configured to generate pulses of current to said RF electrodes; and, d. a control unit connected to said at least one RF generator, said control unit is adapted to control the operation of said RF electrodes; wherein said control unit is adapted to control the operation of said RF electrodes according to a predetermined treatment protocol, such that the same activates or deactivates at least one of said RF electrodes at any predetermined time interval according to a predetermined pattern so as to achieve a particular therapeutic result.

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25-07-2013 дата публикации

Devices for thermally-induced hepatic neuromodulation

Номер: US20130190748A1
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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02-01-2014 дата публикации

Radiation-Based Dermatological Devices and Methods

Номер: US20140005756A1
Принадлежит: Tria Beauty Inc

A self-contained, hand-held device for providing a dermatological treatment may include a device body configured to be handheld by a user, a radiation source including a beam source configured to generate an energy beam, an application end configured to be manually moved across the surface of the skin, a sensor configured to generate signals based on an interaction with the skin, and electronics configured to automatically identify a series of intrinsic skin features based on the sensor signals, and control at least one operational parameter of the radiation source based at least on the identification of such skin features.

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20-02-2014 дата публикации

Low profile fluid enhanced ablation therapy devices and methods

Номер: US20140052117A1
Автор: Michael G. Curley
Принадлежит: Thermedical Inc

Low profile devices and methods for delivering fluid enhanced ablation therapy are provided herein. In one embodiment, an ablation device is provided that includes an elongate body having proximal and distal ends, an inner lumen extending therethrough and at least one outlet port formed therein and configured to deliver fluid to surrounding tissue. The device can also include at least one ablation element disposed along a length of the body adjacent to the at least one outlet port and configured to deliver energy to surrounding tissue, as well as at least one heating element disposed within the inner lumen of the elongate body. The device further includes a handle having proximal and distal ends, the distal end of the handle being coupled to the proximal end of the elongate body. Further, a longitudinal axis of the elongate body extends at an angle to a longitudinal axis of the handle.

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20-02-2014 дата публикации

Modulation of nerves that innervate the liver

Номер: US20140052121A1
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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06-03-2014 дата публикации

Neuromodulation methods using balloon catheter

Номер: US20140066924A1
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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06-01-2022 дата публикации

Surgical cutting device

Номер: US20220000536A1
Принадлежит: Fulmer Instruments LLC

A cordless surgical knife comprises an enclosure and a blade extending from the enclosure. The enclosure contains a differential amplifier circuit configured to provide an RF signal, an output monitor feedback circuit, a return monitor feedback circuit, and a microprocessor that receives data from the feedback circuits and adjusts the RF signal. The enclosure contains a receiving antenna that is operable to receive a wireless signal associated with the RF signal from tissue of a patient. A transmitting antenna may be in electrical contact with tissue of the patient and transmit the wireless signal. Optionally, both the receiving antenna and transmitting antenna include at least two separate inductive circuits aligned on different planes, or each of the receiving antenna and the transmitting antennas is encapsulated inside an enclosure floating in a liquid so that the antennas are aligned by gravity.

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07-01-2021 дата публикации

Optimizing Treatment Using TTFields by Changing the Frequency During the Course of Long Term Tumor Treatment

Номер: US20210000528A1
Автор: DISHON Matan, PALTI Yoram
Принадлежит: Novocure GmbH

Tumors can be treated with an alternating electric field. The size of cells in the tumor is determined prior to the start of treatment by, for example, biopsy or by inverse electric impedance tomography. A treatment frequency is chosen based on the determined cell size. The cell size can be determined during the course of treatment and the treatment frequency is adjusted to reflect changes in the cell size. A suitable apparatus for this purpose includes a device for measuring the tumor impedance, an AC signal generator with a controllable output frequency, a processor for estimating the size of tumor cells and setting the frequency of the AC signal generator based thereon, and at least one pair of electrodes operatively connected to the AC signal generator such that an alternating electric field is applied to the tumor. 1. An apparatus for adaptively treating a tumor with an alternating electric field , the apparatus comprising:an AC signal generator having an output;at least one pair of electrodes operatively connected to the output of the AC signal generator such that an alternating electric field is applied to the tumor to selectively destroy cells in the tumor, wherein the AC signal generator is configured to apply a first alternating electrical signal to the output for a first period of time;an electrical impedance tomography device for measuring an impedance of the tumor to account for expected changes that occur as a result of treating the tumor for the first period of time; anda processor configured to adjust a parameter of treatment based on the measured impedance of the tumor after the first period of time, and further configured to account for changes in the tumor that have occurred during the first period of time by controlling the AC signal generator so that the AC signal generator applies a second alternating electrical signal to the output for a second period of time using the adjusted parameter of treatment,wherein the second period of time is ...

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10-01-2019 дата публикации

FEEDBACK SYSTEM FOR CRYOABLATION OF CARDIAC TISSUE

Номер: US20190008572A1
Принадлежит:

A method and system for providing lesion depth feedback during an ablation procedure. In particular, the method and system provide feedback data or information relating to lesion depth in myocardial tissue during a cryoablation procedure. A plurality of tissue temperature measurements may be transmitted from a plurality of thermocouples disposed on a cryotreatment element, which measurements may be used to determine a slope of change in temperature sensed by each thermocouple over time. The circulation of coolant through the treatment element may be adjusted when the slope changes. A change in slope may indicate that the cryoablation temperatures have passed through target myocardial tissue into non-target, non-myocardial tissue, which may result in collateral damage to structures near the heart. 1. A method for assessment of ablation lesion depth in myocardial tissue , the method comprising:taking a plurality of temperature measurements with one or more thermocouples;determining a rate of change in temperature for each of the one or more thermocouples; andadjusting a temperature of a treatment element in contact with the myocardial tissue when the rate of change in temperature changes.2. The method of claim 1 , wherein the temperature of the treatment element is adjusted when the rate of change in temperature increases negatively.3. The method of claim 1 , wherein the temperature of the treatment element is adjusted when the rate of change in temperature decreases.4. The method of claim 2 , wherein the treatment element is a cryoballoon claim 2 , and the one or more thermocouples are disposed on the cryoballoon.5. The method of claim 4 , wherein the cryoballoon is in fluid communication with a coolant supply reservoir.6. The method of claim 5 , wherein adjusting the temperature of the treatment element includes adjusting a flow of coolant within the cryoballoon.7. The method of claim 6 , wherein adjusting the flow of coolant includes at least one of stopping and ...

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10-01-2019 дата публикации

Optical Feedback RF Ablator and Ablator Tip

Номер: US20190008586A1
Принадлежит: St Jude Medical LLC

An ablation catheter comprises an elongated catheter body; at least one ablation element disposed in a distal portion which is adjacent the distal end of the catheter body; an illumination optical element disposed in the distal portion, the illumination optical element being light-transmissive to emit light from the illumination optical element to the targeted tissue region; and a collection optical element disposed in the distal portion, the collection optical element being light-transmissive to collect one or more of returned, backscattered or newly excited light from the targeted tissue region. The illumination or excitation optical element and the collection optical element are axially spaced from one another and axially optically isolated from one another within the distal portion to substantially prevent light from traveling between the illumination optical element and the collection optical element along a path within the distal portion.

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18-01-2018 дата публикации

SYSTEMS AND METHODS FOR ADAPTIVE SKIN TREATMENT

Номер: US20180014777A1
Принадлежит:

According to an aspect of some embodiments of the present invention there is provided a method of dynamically adapting a facial treatment based on a current facial skin profile, comprising: using at least one sensor for measuring at least one current value of at least one variable skin characteristic of facial skin of a patient; acquiring at least one personal skin characteristic of facial skin of the patient; calculating a current facial skin status of the patient according to the at least one personal skin characteristic and the at least one current value; determining instructions to operate a treatment applicator according to the current facial skin status; and instructing the treatment applicator according to the instructions. 1. A computer implemented method of dynamically adapting a facial treatment based on a current facial skin profile , comprising:using at least one sensor for measuring at least one current value of at least one variable skin characteristic of facial skin of a patient;acquiring at least one personal skin characteristic of facial skin of the patient;calculating a current facial skin status of the patient according to the at least one personal skin characteristic and the at least one current value;calculating code instructions for operating a treatment applicator according to the current facial skin status; andactivating the treatment applicator according to the code instructions.2. The method of claim 1 , wherein calculating the current facial skin status of the patient is performed based on code executing a machine learning algorithm trained using a training set storing at least one facial skin characteristic for each of a plurality of different patients.3. The method of claim 2 , wherein the training set stores at least one calculated current facial skin status of each of the plurality of different patients claim 2 , calculated based on at least one measured current value for at least one variable skin characteristic and at least one ...

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17-01-2019 дата публикации

APPARATUS FOR EFFECTIVE ABLATION AND NERVE SENSING ASSOCIATED WITH DENERVATION

Номер: US20190015002A1
Принадлежит:

An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes near the distal ends of the needles allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media. 1. A catheter for sensing the activity from nerves outside of the lumen of a target vessel of a human body comprising:a catheter body having a distal end for insertion into a patient, a proximal end for controlling the movement of at least one needle, and a central axis extending in a longitudinal direction;a connector configured to connect to external electronic equipment outside of a proximal end of the catheter, said equipment having a sensing subsystem configured for sensing local nerve activity within a patient, and configured to be connected to at least one additional electrode in electrical contact with the patient;at least one needle guiding element adapted to expand outwardly from the catheter body toward the interior wall of the target vessel;at least one needle, the needle having at least one distal electrode, the needle adapted to be advanced outwardly, guided by the at least one needle guiding element to penetrate and advance through the interior wall of the ...

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17-01-2019 дата публикации

MEDICAL DEVICE WITH FORWARD AND SIDEWARD ABLATION MONITORING ULTRASOUND TRANSDUCERS

Номер: US20190015072A1
Принадлежит:

The invention relates to ultrasound imaging method and apparatus suitable for minimally invasive ultrasound diagnostic devices in cardiac ablation monitoring and in tumor ablation monitoring. The present invention proposes an assembly of forward and side-facing transducers and a system of embedded forward and side-facing transducers in apertures on surfaces of the assembly. This provides control of the acoustic properties of the transducer and improved ablation monitoring when the assembly is incorporated in a medical device. 115-. (canceled)16. A combined ablation and ultrasound imaging catheter for insertion within a body , the catheter having a catheter tip comprising:an ablation cap having a distal-facing aperture and a plurality of lateral-facing apertures formed through the ablation cap, wherein the plurality of lateral-facing apertures are located proximal of the distal facing aperture, and are arrayed around a circumference of the ablation cap;an ultrasound transducer system fixed within the ablation cap and having:a first ultrasound transducer element configured to follow an ablation procedure in a first direction through the distal-facing aperture of the ablation cap, the first direction orientated primarily distally away from the catheter tip;a plurality of second ultrasound transducer elements located proximal to the first ultrasound transducer element, the plurality of second ultrasound transducer elements arrayed about the circumference of the ablation cap and configured to follow the ablation procedure through the plurality of lateral-facing apertures of the ablation cap in a plurality of second directions, respectively, the plurality of second directions orientated laterally away from the catheter tip and different from the first direction.17. The catheter of claim 16 , wherein the ablation electrode comprises an RF ablation electrode.18. The catheter of claim 16 , wherein the first and second ultrasound transducer elements are mounted on a base ...

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21-01-2021 дата публикации

Electrically based medical treatment device and method

Номер: US20210015546A1
Автор: Jongju Na
Принадлежит: Individual

Embodiments of medical treatment including skin treatment using electrical energy, especially with the primary purpose for skin treatment for aesthetics are described generally herein. Other embodiments may be described and claimed.

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10-02-2022 дата публикации

SYSTEM AND METHOD FOR INTRA-OPERATIVE PERCUTANEOUS ABLATION PLANNING

Номер: US20220039865A1
Принадлежит:

Apparatus, systems and methods for percutaneous ablation of a tumor in a subject, and more specifically, percutaneous tumor ablation with the ability for real-time, intra-operative ablation planning, execution and adjustment. 1. An image processing apparatus for supporting an ablation or radiotherapy process or planning , comprising: detects a region of interest in an image, subject to an ablation or radiotherapy process or ablation or radiotherapy planning;', 'identifies the position of a needle in the image;', 'calculates a trajectory and depth of the needle based on an insertion information of the needle;', 'causes a display to display the needle trajectory and depth on the image;', 'allows an end user to set an ablation zone in the region of interest, and an ablation size in the region of interest; and', 'adjust the needle trajectory and depth to reflect the ablation zone and ablation size set by the end user., 'a processor configured for intra-operative operation which2. The apparatus of claim 1 , wherein the processor allows the end user to reset the ablation zone or ablation size claim 1 , intra-operatively claim 1 , and adjust the needle trajectory and depth to reflect the resetting.3. The apparatus of claim 1 , wherein the needle is a multiple parallel needle for additional length.4. The apparatus of claim 1 , wherein the processor further operates to pre-segment a lesion in the ablation zone based on feedback from the end user.5. The apparatus of claim 1 , wherein the processor further operates to provide real-time feedback of a minimum ablation margin to the end user.6. The apparatus of claim 1 , wherein the processor further operates to provide real-time feedback of a maximum ablation margin to the end user.7. The apparatus of claim 1 , wherein the processor further operates to provide real-time feedback of a percent coverage of a tumor.8. The apparatus of claim 7 , wherein the percent coverage of the tumor is derived from a minimum ablation margin and ...

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24-01-2019 дата публикации

Surgical instrument with user adaptable algorithms

Номер: US20190021783A1
Принадлежит: Ethicon LLC

Various forms are directed to systems and methods for dissection and coagulation of tissue. A surgical instrument includes an end effector configured to dissect and seal tissue at a distal end thereof, and a selector switch having a plurality of surgical modes. A generator is electrically coupled to the surgical instrument and is configured to deliver energy to the end effector. Each surgical mode of the selector switch corresponds to an algorithm for controlling the power delivered from the generator to the end effector, and each algorithm corresponding to the plurality of surgical modes is configured to allow a user to control the power output level of the generator.

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24-01-2019 дата публикации

MICROWAVE ABLATION GENERATOR CONTROL SYSTEM

Номер: US20190021792A1
Принадлежит:

A microwave energy delivery and measurement system, including a microwave energy source configured to delivery microwave energy to a microwave energy delivery device, a measurement system configured to measure at least one parameter of the microwave energy delivery device and a switching network configured to electrically isolate the microwave energy source and the measurement system. The measurement system is configured to actively measure in real time at least one parameter related to the microwave energy delivery device. 120-. (canceled)21. A system comprising:a switch configured to couple to a transmission line and configured to connect a microwave energy source to a microwave energy delivery device for a first period and to disconnect the microwave energy source from the microwave energy delivery device for a second period; anda measurement system configured to couple to the transmission line and configured to measure at least one parameter of microwave energy propagating through the transmission line in at least the second period.22. The system of claim 21 , wherein the measurement system includes an active measurement system configured to measure a parameter of the microwave energy propagating through the transmission line in the second period.23. The system of claim 22 , wherein the parameter includes broadband scattering parameters claim 22 , andwherein the active measurement system transmits a broadband microwave signal to the microwave energy delivery device and measures broadband scattering parameters in the second period.24. The system of claim 22 , wherein the active measurement system is a precision network analyzer.25. The system of claim 22 , further comprising a dual directional coupler configured to couple to the transmission line claim 22 ,wherein the measurement system further includes a passive measurement system coupled to the dual directional coupler and configured to measure a second parameter of microwave energy propagating through the ...

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17-02-2022 дата публикации

Multi-applicator system and method for body contouring

Номер: US20220047315A1
Принадлежит: Zeltiq Aesthetics Inc

Systems, methods, and devices for treating a subject are described herein. In some embodiments, an applicator for selectively affecting a subject's subcutaneous tissue is provided. The applicator can include: a housing; a treatment cup mounted in the housing, wherein the treatment cup defines a tissue-receiving cavity and includes a temperature-controlled surface; at least one thermal device coupled to the treatment cup and configured to receive energy via a flexible connector coupled to the applicator and to cool the temperature-controlled surface; an at least one vacuum port coupled to the treatment cup and configured to provide a vacuum to draw the subject's tissue into the tissue-receiving cavity and against at least a portion of a treatment area of the temperature-controlled surface to selectively damage and/or reduce the subject's subcutaneous tissue.

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07-02-2019 дата публикации

Ablation check pulse routine and integration for electroporation

Номер: US20190038171A1
Автор: Brian T. HOWARD
Принадлежит: MEDTRONIC INC

Devices, systems, and methods relating to a low-voltage, pre-treatment pulse routine for evaluating a potential for non-target tissue damage from the delivery of energy, such as electroporation energy to an area of target tissue. In one embodiment, a medical system includes a medical device having a treatment element; and a control unit in communication with the medical device, the control unit being configured to: deliver a low-voltage, pre-treatment pulse routine through the treatment element to an area of target tissue; determine whether the low-voltage, pre-treatment pulse routine has a stimulation effect on an area of non-target tissue; and deliver an ablation energy routine through the treatment element to the area of target tissue when the control unit determines that the low-voltage, pre-treatment pulse routine does not have a stimulation effect on the area of non-target tissue.

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15-02-2018 дата публикации

ELECTROSURGICAL (RF) MEDICAL INSTRUMENTS FOR CUTTING AND COAGULATING TISSUE

Номер: US20180042658A1
Принадлежит:

An electrosurgical device is disclosed. The electrosurgical device includes a handle, a shaft extending distally from the handle, and an end effector coupled to a distal end of the shaft. The end effector comprises a first electrode and a second electrode. The second electrode includes a first position and a second position. The second electrode is configured to move from the first position to the second position when a force is applied to the end effector by a tissue section. The first electrode and the second electrode define a treatment area when the second electrode is in the second position. 1. An electrosurgical instrument comprising:a pencil-grip handle;a shaft coupled to the pencil grip handle; and a body;', 'a source electrode; and', 'one or more return electrodes,, 'an end effector coupled to the shaft, wherein the end effector compriseswherein the source electrode and the one or more return electrodes are configured to provide an electrosurgical signal to a tissue.2. The electrosurgical instrument of claim 1 , wherein the electrosurgical signal comprises a radio frequency (RF) signal.3. The electrosurgical instrument of claim 1 , wherein the pencil-grip handle comprises a power source and is cordless.4. The electrosurgical instrument of claim 1 , wherein the source electrode is disposed on a center portion of the body and the one or more return electrodes are disposed on a lateral portion of the body.5. The electrosurgical instrument of claim 1 , wherein the body defines an oval shape.6. The electrosurgical instrument of claim 1 , wherein the one or more return electrodes each comprise a first return electrode and a second return electrode.7. The electrosurgical instrument of claim 6 , further comprising an electrosurgical generator coupled to the end effector claim 6 , wherein the electrosurgical generator is configured to produce the electrosurgical signal comprising a first phase claim 6 , a second phase claim 6 , and a third phase claim 6 , wherein ...

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10-03-2022 дата публикации

Multi-channel rf impedance

Номер: US20220071685A1
Автор: Hongxuan Zhang
Принадлежит: Smith and Nephew Orthopaedics AG

Electrosurgical systems and methods. At least one example embodiment is a method including: performing a first electrosurgical activity by way of first energy at a first frequency applied to an active electrode of an electrosurgical wand, the application of the first energy by way of an electrosurgical generator, and the first electrosurgical activity produces a first effect that is tissue-altering; and measuring an electrosurgical parameter by way of a second energy at a second frequency applied to the active electrode, the measuring simultaneously with the performing of the first electrosurgical activity, and the second frequency different than the first frequency.

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01-03-2018 дата публикации

SYSTEM AND METHOD FOR MONITORING ABLATION SIZE

Номер: US20180055567A1
Автор: Brannan Joseph D.
Принадлежит:

A system for monitoring ablation size includes a power source including a microprocessor for executing one or more control algorithms. A microwave antenna is configured to deliver microwave energy from the power source to tissue to form an ablation zone. A plurality of spaced-apart electrodes is operably disposed along a length of the microwave antenna. The plurality of spaced-apart electrodes is disposed in electrical communication with one another and each of the plurality of spaced-apart electrodes has a threshold impedance associated therewith corresponding to the radius of the ablation zone. 119-. (canceled)20. A system for monitoring ablation size , comprising:a power source; and an elongate shaft;', 'a plurality of proximal spaced-apart electrodes disposed on the elongate shaft;', 'a distal electrode disposed on the elongate shaft distally of the plurality of proximal spaced-apart electrodes;', 'a feedline having a distal radiating section disposed within the elongate shaft;', 'a first sensor disposed on at least one of the plurality of proximal spaced-apart electrodes; and', 'a second sensor disposed on the distal electrode., 'a microwave antenna configured to transmit microwave energy from the power source to tissue to form an ablation zone, the microwave antenna including21. The system according to claim 20 , wherein the plurality of proximal spaced-apart electrodes is disposed along a longitudinal axis of the elongate shaft and in electrical communication with one another.22. The system according to claim 20 , wherein the elongate shaft includes a distal tip and the distal electrode is disposed at the distal tip.23. The system according to claim 20 , wherein the microwave antenna includes a dielectric sheath positioned along the elongate shaft and encasing the plurality of proximal spaced-apart electrodes and the distal electrode to allow current to flow from the plurality of proximal spaced-apart electrodes to the distal electrode.24. The system ...

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05-03-2015 дата публикации

Anchored RF Ablation Device for The Destruction of Tissue Masses

Номер: US20150066003A1
Принадлежит: Halt Medical Inc

The inventive ablation element comprises an elongated cannula having a proximal end and a distal end. The cannula defines an internal lumen and a cannula axis. A plurality of conductors contained within the lumen, each having a proximal end proximate the proximal end of the cannula, and a distal end proximate the distal end of the cannula. A plurality of ablation stylets each has a proximal end and a distal end, and each coupled to the distal end of a respective conductor, the conductors together with their respective stylets being mounted for axial movement. A trocar point defined proximate the distal end of the cannula. A deflection surface positioned between the trocar point and the proximal end of the cannula, the deflection surface being configured and positioned to deflect at least some of the stylets laterally with respect to the cannula axis in different directions defining an ablation volume.

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28-02-2019 дата публикации

CHEMICAL MODULATION OF NERVES INNERVATING THE LIVER

Номер: US20190059969A1
Принадлежит:

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery. 1. (canceled)2. A method of altering glucose levels , the method comprising:inserting a catheter into a vasculature of a subject,wherein said catheter comprises a distal end configured to disrupt one or more nerves,advancing the distal end of the catheter to a location within a portion of a common hepatic artery of the vasculature; anddisrupting one or more nerves of a hepatic plexus surrounding the portion of the common hepatic artery to decrease a glucose level within the subject.3. The method of claim 2 , wherein the distal end comprises a cutting portion configured to transect said one or more nerves.4. The method of claim 2 , wherein the distal end comprises a compression member configured to apply mechanical compression to disrupt the one or more nerves.5. The method of claim 4 , wherein the compression member comprises a shape memory compression clip.6. The method of claim 4 , wherein the compression member comprises a vascular wall clamp.7. The method of claim 6 , wherein the catheter comprises a plurality of suction holes configured to create suction on a wall surface of the common hepatic artery.8. The method of claim 2 , wherein the distal end is configured to hold a cooling fluid configured to cryogenically disrupt said one or more nerves.9. The method of claim 8 , wherein the distal end comprises a balloon.10. The method of claim 2 , wherein the distal end comprises a delivery portion configured to deliver a chemoablative agent to ablate said one or more nerves.11. The method of ...

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28-02-2019 дата публикации

NON-INVASIVE RADIO-FREQUENCY ABLATION SYSTEM

Номер: US20190059981A1
Автор: SU Sea-Quan
Принадлежит:

An ablation device of a non-invasive radio-frequency ablation system includes a substrate having a first surface; a first electrode disposed on the first surface; a second electrode disposed on the first surface and adjacent to the first electrode; a moving unit electrically connected to the second electrode for moving the second electrode to regulate the distance between the second electrode and the first electrode; and a radio frequency generator connected to the ablation device for providing a radio frequency current to the first electrode and the second electrode. According to a method using the ablation device, the first and second electrodes are brought into contact with a third surface belonging to a subject in need of treatment, and the radio frequency current is applied to the electrodes to carry out a treatment procedure. The treatment depth and area are adjusted by changing the relative distance between the electrodes. 1. A non-invasive radio-frequency ablation system , comprising: a substrate having a first surface;', 'a first electrode disposed on the first surface; and', 'a second electrode disposed on the first surface and adjacent to the first electrode; and', 'a moving unit electrically connected to the second electrode and moving the second electrode to regulate the distance between the second electrode and the first electrode; and, 'an ablation device comprisinga radio frequency generator connected to the ablation device for providing a radio frequency current to the first electrode and the second electrode.2. The radio-frequency ablation system according to claim 1 , wherein the moving unit includes a ball screw.3. The radio-frequency ablation system according to claim 1 , wherein the ablation device further comprises a cooling unit disposed on the first surface and between the first electrode and second electrode.4. The radio-frequency ablation system according to claim 3 , wherein the cooling unit includes a cooling chip and/or refrigerant.5. ...

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17-03-2022 дата публикации

Ultrasonic medical instrument having variable focusing depth of ultrasonic wave generating unit

Номер: US20220079650A1
Принадлежит: Jeisys Medical Inc

Embodiments of the inventive concept provide an ultrasonic medical instrument moving horizontally by adjusting a depth wise location of an ultrasonic wave generating unit while not influencing an internal volume of a cartridge and variously setting focusing depths of ultrasonic waves in skin.

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17-03-2022 дата публикации

SYSTEM AND METHODS FOR INSERTION DEPTH TRACKING

Номер: US20220079671A1
Принадлежит:

A system and an ablation probe of a system monitors insertion depth during an ablation procedure. The ablation probe includes a housing, an elongated shaft extending from the housing, a distance sensor operably coupled to the housing, and a microcontroller operably coupled to the distance sensor. The elongated shaft is configured to be inserted through a skin surface. The distance sensor measures a distance value between the housing and the skin surface. The microcontroller receives the measured distance value from the distance sensor, calculates an insertion depth value of the elongated shaft based on the received measured distance value, and causes a display unit to display the calculated insertion depth value. 1. An ablation probe comprising:a housing;an elongated shaft extending from the housing and configured to be inserted through a skin surface;a distance sensor operably coupled to the housing and configured to measure a distance value between the housing and a skin surface; and{'claim-text': ['receive the measured distance value from the distance sensor; and', 'calculate an insertion depth value of the elongated shaft based on the received measured distance value.'], '#text': 'a microcontroller operably coupled to the distance sensor, the microcontroller configured to:'}2. The ablation probe according to claim 1 , wherein the microcontroller is operably coupled to a display unit and is further configured to cause the display unit to display the calculated insertion depth value.3. The ablation probe according to claim 1 , wherein the distance sensor includes at least one of a laser claim 1 , ultrasonic claim 1 , or IR sensor.4. The ablation probe according to claim 1 , wherein the microcontroller calculates the insertion depth value by subtracting the received measured distance value from a length of the elongated shaft.5. The ablation probe according to claim 1 , further comprising a display unit operably coupled to the housing.6. The ablation probe ...

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15-03-2018 дата публикации

Temperature monitoring electrosurgical system

Номер: US20180071010A1
Принадлежит: Kogent Surgical LLC

A temperature monitoring electrosurgical system may include a first forceps arm, a second forceps arm, a temperature monitoring system, and a system control. The first forceps arm may include a first thermocouple electrically connected to a first temperature sense of the temperature monitoring system. The second forceps arm may include a second thermocouple electrically connected to a second temperature sense of the temperature monitoring system. The system control may be configured to compare a measured temperature of the first thermocouple and the second thermocouple to a user defined cauterization temperature setting. The system control may be configured to increase a bipolar output power if the measured temperature is less than the cauterization temperature setting. The system control may be configured to decrease the bipolar output power if the measured temperature is greater than the cauterization temperature setting.

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07-03-2019 дата публикации

NEUROMODULATION FOR METABOLIC CONDITIONS OR SYNDROMES

Номер: US20190069942A1
Принадлежит:

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery. 1. (canceled)2. (canceled)3. A method of facilitating hepatic neuromodulation using a laparoscopic approach , the method comprising:laparoscopically delivering a radiofrequency energy delivery device within a subject;positioning a distal portion of the radiofrequency energy delivery device at a location adjacent a portion of a common hepatic artery,wherein the distal portion of the radiofrequency energy delivery device comprises at least one electrode; andcausing radiofrequency energy to be applied by the at least one electrode to one or more nerves of the hepatic plexus sufficient to ablate the one or more nerves in a manner that facilitates a reduction in at least one of a blood glucose level or a lipoprotein level in the subject; andremoving the radiofrequency energy delivery device from the subject.4. The method of claim 3 ,wherein the radiofrequency energy is in a range of 50 kHz to 5 MHz,wherein the radiofrequency energy heats the one or more nerves to a temperature of up to 90 degrees Celsius; andwherein the one or more nerves are sympathetic nerves of the hepatic plexus.5. The method of claim 3 , further comprising confirming ablation of the one or more nerves.6. The method of claim 3 , further comprising maintaining contact between the at least one electrode and the portion of common hepatic artery at a contact pressure of between 0.1 g/mmand 10 g/mm.7. A method of facilitating hepatic neuromodulation using a laparoscopic approach claim 3 , the method comprising:laparoscopically ...

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16-03-2017 дата публикации

Ablation System for Large-area Surface Coagulation of Biological Tissue

Номер: US20170071652A1
Принадлежит: Erbe Elecktromedizin GmbH

The ablation system ( 10 ) according to the invention works with an ablation probe ( 12, 12 a ) that comprises two alternatingly working spark plasma electrodes ( 31, 32 ). They generate a plasma beam ( 47, 48 ) having a non-circular cross-section, which beam is to be guided—transversely with respect to the large longitudinal axis of its preferably oval cross-section—over the tissue to be ablated, in particular the mucosa ( 14 ). In doing so, it is possible to treat large-area tissue regions by means of a reliable and easily controllable procedure.

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19-03-2015 дата публикации

Electrosurgical (rf) medical instruments for cutting and coagulating tissue

Номер: US20150080891A1
Принадлежит: Ethicon Endo Surgery Inc

An electrosurgical device is disclosed. The electrosurgical device includes a handle, a shaft extending distally from the handle, and an end effector coupled to a distal end of the shaft. The end effector comprises a first electrode and a second electrode. The second electrode includes a first position and a second position. The second electrode is configured to move from the first position to the second position when a force is applied to the end effector by a tissue section. The first electrode and the second electrode define a treatment area when the second electrode is in the second position.

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31-03-2022 дата публикации

System and method for suppressing apoe gene for sarcoma treatment

Номер: US20220096140A1

A method for applying cold atmospheric plasma treatment to target tissue comprising the steps of treating a patient with a pharmaceutical for suppressing apolipoprotein E genes, selecting through a graphical user interface a particular soft tissue sarcoma cell line associated with target tissue, retrieving, with said computing device, settings data associated with said selected soft tissue sarcoma cell line from a database of cell line data and associated settings data in a storage, and applying, with said computing device, said retrieved settings data to a cold atmospheric plasma system.

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12-03-2020 дата публикации

MANAGING SIMULTANEOUS MONOPOLAR OUTPUTS USING DUTY CYCLE AND SYNCHRONIZATION

Номер: US20200078079A1
Принадлежит:

Aspects of the present disclosure are presented for managing simultaneous outputs of surgical instruments. In some aspects, methods are presented for synchronizing the current frequencies. In some aspects, methods are presented for conducting duty cycling of energy outputs of two or more instruments. In some aspects, systems are presented for managing simultaneous monopolar outputs of two or more instruments, including providing a return pad that properly handles both monopolar outputs in some cases. 1. A method of a surgical system for providing simultaneous activation of a first electrosurgical unit and a second electrosurgical unit on a patient , the method comprising:generating, by the system, a first energy output having a first frequency from the first electrosurgical unit;simultaneously, generating, by the system, a second energy output having a second frequency from the second electrosurgical unit; wherein the second frequency is different than the first frequency;measuring, by the system, a magnitude of impedance arising from the simultaneous generation of the first energy output and the second energy output, wherein the magnitude of impedance is proportional to the difference in frequency between the second frequency and the first frequency;determining that the magnitude of the impedance exceeds a predetermined threshold; andbased on the determination, performing an adjustment to correct for the impedance exceeding the predetermined threshold.2. The method of claim 1 , wherein the adjustment comprises providing an alert that the magnitude of the impedance is in an unacceptable range.3. The method of claim 1 , wherein the adjustment comprises automatically limiting functionality of one or both of the first electrosurgical unit and the second electrosurgical unit.4. The method of claim 1 , wherein the adjustment comprises automatically reducing power output of one or both of the first electrosurgical unit and the second electrosurgical unit.5. The method of ...

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12-03-2020 дата публикации

SURGICAL INSTRUMENT UTILIZING DRIVE SIGNAL TO POWER SECONDARY FUNCTION

Номер: US20200078082A1
Принадлежит:

A surgical instrument connectable to a surgical energy module that is configured to provide a first drive signal at a first frequency range for driving a first energy modality and a second drive signal at a second frequency range for driving a second energy modality is provided. The surgical instrument can comprise a surgical instrument component configured to receive power from a direct current (DC) power source, an end effector, and a circuit. The circuit can be configured to convert the first electrical signal to a DC voltage, apply the DC voltage to the surgical instrument component, and deliver the second energy modality to the end effector according to the second drive signal. Alternatively, the circuit can be disposed within a cable assembly configured to connect the surgical instrument to the surgical energy module. 1. A surgical instrument connectable to a surgical energy module , the surgical energy module configured to provide a first drive signal at a first frequency range for driving a first energy modality and a second drive signal at a second frequency range for driving a second energy modality , the surgical instrument comprising:a surgical instrument component configured to receive power from a direct current (DC) power source;an end effector; and receive the first electrical signal from the surgical energy module;', 'convert the first electrical signal to a DC voltage;', 'apply the DC voltage to the surgical instrument component;', 'receive the second electrical signal from the surgical energy module; and', 'deliver the second energy modality to the end effector according to the second drive signal., 'a circuit coupled to the surgical instrument component and the end effector, the circuit configured to2. The surgical instrument of claim 1 , wherein the circuit comprises a rectifier configured to convert the first drive signal to the DC output voltage.3. The surgical instrument of claim 2 , wherein the rectifier is configured to convert an ...

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12-03-2020 дата публикации

Method for controlling a modular energy system user interface

Номер: US20200078106A1
Принадлежит: Ethicon LLC

A method for controlling a user interface of a modular energy system. The modular energy system comprises a header module and a display screen on which the user interface is displayed. The modular energy system can detect attachment of a first module thereto, control the user interface to display one or more first user interface elements corresponding to the first module, detect attachment of a second module to the modular energy system, control the user interface to resize the one or more first user interface elements to accommodate display of one or more second user interface elements corresponding to the second module, and control the user interface to display the one or more second user interface elements. The various UI elements can correspond to the particular module type that is being connected to the modular energy system.

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12-03-2020 дата публикации

Energy module for drivig multiple energy modalities through a port

Номер: US20200078117A1
Принадлежит: Ethicon LLC, Plexus Corp

An energy module connectable to a surgical instrument is disclosed. The energy module can include a circuit, which can include a first amplifier and a second amplifier coupled to a port of the energy module to which a surgical instrument is connectable. The first amplifier can be configured to generate a first drive signal at a first frequency range and the second amplifier can be configured to generate a second drive signal at a second frequency range. The circuit can be configured to control the amplifiers to deliver the first drive signal, the second drive signal, and/or a combination of the first and second drive signals to a surgical instrument connected to the port.

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26-03-2015 дата публикации

Systems and methods for improving efficiency of electrosurgical generators

Номер: US20150088118A1
Принадлежит: COVIDIEN LP

An electrosurgical generator is presented including a radio frequency (RF) amplifier coupled to an electrical energy source and configured to generate electrosurgical energy, the RF amplifier including an inverter configured to convert a direct current (DC) to an alternating current (AC), and a plurality of sensors configured to sense voltage and current of the generated electrosurgical energy. The electrosurgical generator further includes a controller coupled to the RF amplifier and the plurality of sensors. The electrosurgical may be further configured to determine a power level based on the sensed voltage and the sensed current, determine an efficiency of the electrosurgical generator, and insert a predetermined integer number of off cycles when the efficiency of the electrosurgical generator reaches a threshold power efficiency.

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25-03-2021 дата публикации

GUIDING CARDIAC ABLATION USING MACHINE LEARNING (ML)

Номер: US20210085387A1
Принадлежит:

A system includes an interface and a processor. The interface is configured to receive data that characterizes an initial ablation operation applied to a region of a heart of a patient. The processor is configured to automatically specify, based on the received data, if found required, a complementary ablation operation to be applied to the region. 1. A system for guiding cardiac ablation , the system comprising:an interface configured to receive data that characterizes an initial ablation operation applied to a region of a heart of a patient; anda processor, which is configured to automatically specify, based on the received data, a complementary ablation operation to be applied to the region.2. The system according to claim 1 , wherein the processor is configured to specify the complementary ablation by assessing a quality of the initial ablation operation claim 1 , and specifying the complementary ablation operation in response to finding that the quality of the initial ablation operation does not meet a quality criterion.3. The system according to claim 1 , wherein the data that characterizes the initial ablation operation comprises at least one of:a lesion depth;a lesion radius;a lesion major axis;a lesion minor axis;a lesion 3D location;a lesion anatomical location; anda lesion surface area.4. The system according to claim 1 , wherein claim 1 , in specifying the complementary ablation operation claim 1 , the processor is configured to specify a location for a repeat ablation.5. The system according to claim 1 , wherein claim 1 , in specifying the complementary ablation operation claim 1 , the processor is configured to indicate a gap in a segment of ablation points.6. The system according to claim 1 , wherein claim 1 , in specifying the complementary ablation operation claim 1 , the processor is configured to specify claim 1 , in real time claim 1 , that an additional ablation is to be performed in proximity to a segment of ablation points.7. The system ...

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05-05-2022 дата публикации

Systems and methods for ablation using non-adjacent bipoles

Номер: US20220133403A1
Автор: Boyce Moon, Eric Olson
Принадлежит: St Jude Medical Cardiology Division Inc

Systems and methods for ablating tissue are provided. An ablation system includes a catheter having a plurality of electrodes, and a controller coupled to the catheter. The controller is configured to select at least one pair of non-adjacent electrodes of the plurality of electrodes, and sequentially apply bipolar stimulation using the at least one selected pair of non-adjacent electrodes.

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05-05-2022 дата публикации

Method and apparatus for rapid and selective transurethral tissue ablation

Номер: US20220133405A1
Автор: Steven R. MICKELSEN
Принадлежит: Boston Scientific Scimed Inc, Farapulse Inc

Catheter systems, tools and methods are disclosed for the selective and rapid application of DC voltage pulses to drive irreversible electroporation for minimally invasive transurethral prostate ablation. In one embodiment, a switch unit is used to modulate and apply voltage pulses from a cardiac defibrillator, while in another, the system controller can be configured to apply voltages to an independently selected multiplicity or subsets of electrodes. Devices are disclosed for more effective DC voltage application including the infusion of cooled fluid to elevate the irreversible electroporation threshold of urethral wall tissue and to selectively ablate regions of prostate tissue alone.

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16-04-2015 дата публикации

Radiofrequency amplifier impedance optimization

Номер: US20150105766A1
Принадлежит: COVIDIEN LP

The present disclosure is directed to an electrosurgical generator including a resonant inverter having an H-bridge and a tank. The generator also includes a pulse width modulation (PWM) controller configured to output PWM timing signals to the H-bridge. A switch is configured to select a modality from among a plurality of modalities and the PWM controller adjusts a frequency of the PWM timing signals based on the selected modality.

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23-04-2015 дата публикации

Modulation of nerves innervating the liver

Номер: US20150112332A1
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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11-04-2019 дата публикации

ELECTROSURGICAL SYSTEM

Номер: US20190105096A1
Принадлежит:

An electrosurgical generator arranged to supply radio frequency (RF) energy to fuse tissue is provided. The generator is arranged to supply RF energy through a removably coupled electrosurgical instrument to fuse tissue grasped by the instrument. The generator monitors a phase angle of the supplied RF energy and adjusts or terminates the supplied RF energy based on the monitored phase angle in comparison to predetermined thresholds and conditions to optimally fuse the tissue. The electrosurgical instrument conducts radio frequency energy to fuse tissue captured between the jaws and a blade to mechanically cut tissue between the jaws. A conductive post positioned on the jaw adjacent to the blade 1. An electrosurgical system comprising:an electrosurgical instrument arranged to grasp and fuse tissue using radio frequency (RF) energy; andan electrosurgical generator connectable to the electrosurgical instrument and configured to supply the RF energy through the electrosurgical instrument, the generator comprising:an RF amplifier arranged to supply RF energy through the electrosurgical instrument in which voltage of the supplied RF energy is applied in a ramping fashion and subsequently held constant.2. The system of wherein the voltage of the supplied RF energy is held constant at a predetermined voltage.3. The system of further comprising a controller arranged to monitor a phase angle of the supplied RF energy claim 2 , the controller signals the RF amplifier to terminate the supply of RF energy when the monitored phase angle is less than a predefined phase value.4. The system of wherein the predefined phase value is less than zero degrees.5. The system of wherein the voltage of the supplied RF energy applied in a ramping fashion starts from a voltage being 25 percent of a predefined voltage setting to a voltage being 80 percent of the predefined voltage setting.6. The system of wherein the voltage of the supplied RF energy is held constant at its current voltage level ...

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10-07-2014 дата публикации

System and method for assessing the formation of a lesion in tissue

Номер: US20140194867A1

A method and system for assessing lesion formation in tissue is provided. The system includes an electronic control unit (ECU) configured to acquire magnitudes for a component of a complex impedance between an electrode and tissue, and the power applied to the tissue during lesion formation. The ECU is configured to calculate a value responsive to the complex impedance component and the power. The value is indicative of a predicted lesion depth, a likelihood the lesion has reached a predetermined depth, or a predicted tissue temperature. The method includes acquiring magnitudes for a component of a complex impedance between an electrode and tissue and the power applied during lesion formation. The method includes calculating a value responsive to the complex impedance component and the power, the value being indicative of a predicted lesion depth, a likelihood the lesion has reached a predetermined depth, and/or a predicted tissue temperature.

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03-05-2018 дата публикации

SURGICAL GENERATOR FOR ULTRASONIC AND ELECTROSURGICAL DEVICES

Номер: US20180116706A9
Принадлежит:

A method for determining motional branch current in an ultrasonic transducer of an ultrasonic surgical device over multiple frequencies of a transducer drive signal. The method may comprise, at each of a plurality of frequencies of the transducer drive signal, oversampling a current and voltage of the transducer drive signal, receiving, by a processor, the current and voltage samples, and determining, by the processor, the motional branch current based on the current and voltage samples, a static capacitance of the ultrasonic transducer and the frequency of the transducer drive signal. 1. A surgical system , comprising:a surgical device, wherein the surgical device comprises an end effector to treat tissue; provide a drive signal to drive the end effector;', 'receive a frequency of the drive signal; and', 'determine a temperature at the end effector considering the frequency of the drive signal., 'a surgical generator in communication with the surgical device, comprising at least one programmable logic device, wherein the at least one programmable logic device is programmed to2. The surgical system of claim 1 , wherein determining the temperature at the end effector comprises training a model of end effector temperature.3. The surgical system of claim 2 , wherein training the model comprises:providing to the model a set of input values including the frequency of the drive signal; andcomparing an output temperature of the model to a known output temperature associated with the set of input values.4. The surgical system of claim 1 , wherein the programmable logic device is further programmed to receive a plurality of input variables describing the end effector claim 1 , wherein the plurality of input variables comprises the frequency of the drive signal.5. The surgical system of claim 4 , wherein the plurality of input variables further comprises at least one of a voltage of the drive signal claim 4 , a current of the drive signal claim 4 , a power of the drive signal ...

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10-05-2018 дата публикации

Anchored rf ablation device for the destruction of tissue masses

Номер: US20180125566A1
Принадлежит: Acessa Health Inc

The inventive ablation element comprises an elongated cannula having a proximal end and a distal end. The cannula defines an internal lumen and a cannula axis. A plurality of conductors contained within the lumen, each having a proximal end proximate the proximal end of the cannula, and a distal end proximate the distal end of the cannula. A plurality of ablation stylets each has a proximal end and a distal end, and each coupled to the distal end of a respective conductor, the conductors together with their respective stylets being mounted for axial movement. A trocar point defined proximate the distal end of the cannula. A deflection surface positioned between the trocar point and the proximal end of the cannula, the deflection surface being configured and positioned to deflect at least some of the stylets laterally with respect to the cannula axis in different directions defining an ablation volume.

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01-09-2022 дата публикации

Pulsed electric field (pef) index

Номер: US20220273353A1
Принадлежит: MEDTRONIC INC

A method and a medical device for determining efficacy of a pulsed electric field (PEF) ablation procedure are disclosed. According to one aspect, the method includes generating at least one pulsed electric field (PEF) pulse to be delivered to at least one electrode of a plurality of electrodes, the at least one electrode being at a distal end of a PEF ablation catheter and being positionable in proximity to a target region of tissue to be ablated. The method also includes determining an index of completeness indicative of a completeness of ablation of the target region of tissue based at least in part on a change in a parameter compared to an expected change in the parameter, the change in the parameter being caused at least in part on an extent of ablation of the target region.

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01-09-2022 дата публикации

Apparatus for treatment of tumors using a treatment object and powering of the treatment object

Номер: US20220273359A1
Автор: David Cohen
Принадлежит: Individual

A device for treatment of a tumor comprises a treatment object for placement in or around the tumor. The treatment object has a heating surface which is placed against tumor tissue and which achieves a controlled treatment temperature that is higher than a patient body temperature. An energy source is external to the treatment object and provides energy to reach the treatment temperature. The energy source may be contactless.

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17-05-2018 дата публикации

ELECTROSURGICAL INSTRUMENT WITH IMPEDANCE TRANSFORMER FOR DELIVERING MICROWAVE ENERGY

Номер: US20180132933A1
Принадлежит:

An electrosurgical instrument for delivering microwave energy having a predetermined frequency into biological tissue in contact with the instrument, wherein the instrument comprises a first coaxial transmission line having a second coaxial transmission line connected to the distal end thereof, the second coaxial transmission line having a length and a characteristic impedance that are configured to match the impedance of the first coaxial transmission line to the load impedance at the distal end of the distal coaxial transmission line when the instrument is in contact with the tissue, at the operating frequency. 1. An electrosurgical instrument configured for delivering microwave frequency energy having a predetermined operating frequency into tissue having a predetermined characteristic impedance in contact with a distal end of the instrument , the instrument comprising:a proximal coaxial transmission line for conveying microwave frequency energy comprising a first inner conductor, a first outer conductor formed coaxially with the first inner conductor, and a first dielectric layer separating the first inner conductor and the first outer conductor;a distal coaxial transmission line for conveying microwave frequency energy comprising a second inner conductor connected to the first inner conductor, a second outer conductor formed coaxially with the second inner conductor and connected to the first outer conductor, and a second dielectric layer separating the second inner conductor and the second outer conductor;wherein a ratio of an inner diameter of the second outer conductor to the outer diameter of the second inner conductor is such that a characteristic impedance of the distal coaxial transmission line is intermediate between a characteristic impedance of the proximal coaxial transmission line and a load impedance at the distal end of the distal coaxial transmission line when the distal end of the instrument is in contact with the tissue; andwherein a length of ...

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02-05-2019 дата публикации

SYSTEM AND METHODS FOR MITIGATING INTERFERENCES BETWEEN ELECTROSURGICAL SYSTEMS

Номер: US20190132062A1
Принадлежит:

Methods and system are provided to mitigate RF interferences during operation of an electrosurgical system. An electrosurgical system configured to output therapeutic RF energy may refrain from outputting RF energy in order to measure an RF interference for a group of candidate frequencies, and to select a frequency from the group of candidate frequencies for which the measured RF interference is below a threshold value, and to produce a feedback signal (a control signal) at the selected frequency to control operation of the electrosurgical system. During operation of the electrosurgical system the feedback signal may be filtered by a BPF whose fundamental frequency is set to the selected frequency, to thus obtain an interference free feedback signal and, consequently, a reliable control of the electrosurgical system. 1. A method of mitigating interferences during operation of an electrosurgical system , comprising: refraining from outputting RF energy;', 'measuring, while refraining from outputting RF energy, an RF interference for a group of candidate frequencies;', 'selecting, from the group of candidate frequencies, a frequency for which the measured RF interference is below a predetermined threshold and generating RF energy at the selected frequency; and', 'controlling operation of the electrosurgical system by using a feedback signal sampled from the generated RF energy., 'by an electrosurgical system configured to output a therapeutic radio frequency (“RF”) energy, performing,'}2. The method as in claim 1 , wherein controlling the operation of the electro surgical system comprises:calculating, using the feedback signal, a value of an operational parameter of the electrosurgical system; andcontrolling the operation of the electrosurgical system based on the calculated value of the operational parameter.3. The method as in claim 2 , wherein the calculated operational parameter is an impedance (Z) at the output of the electrosurgical system.4. The method as in ...

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08-09-2022 дата публикации

Apparatus and method for electrosurgery

Номер: US20220280224A1
Автор: Akinori KABAYA
Принадлежит: OLYMPUS MEDICAL SYSTEMS CORP

Methods and systems for treating biological tissue using high frequency electrical energy includes a cycle comprising a desiccating phase, a cutting phase and a coagulating phase. During the dessicating phase of the cycle, a first high frequency electrical energy applied to the tissue for desiccating the tissue is modulated. A first parameter associated with application of the first high frequency electrical energy to the tissue for desiccating the tissue is estimated. During the cutting phase, cutting energy applied to the tissue for cutting the tissue is then modulated based on the first parameter. During the coagulating phase, a second high frequency electrical energy applied to the tissue for coagulating the cut tissue is modulated.

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10-06-2021 дата публикации

Apparatus and method for precise mechanical tissue ablation using pressure modulated focused ultrasound

Номер: US20210169515A1

An apparatus for tissue ablation according to an embodiment of the present disclosure includes an ultrasound output unit to output focused ultrasound, and a control unit to control an intensity of the focused ultrasound, wherein the control unit may be configured to control the intensity of the focused ultrasound below a setting value, when a first condition in which a vapor bubble is formed in a tissue or a second condition in which a temperature of the tissue reaches a threshold is accomplished during the output of the focused ultrasound to the tissue. According to this embodiment, it is possible to precisely control vapor bubble dynamics without generating the shockwave scattering effect by instantaneously controlling the acoustic pressure and the intensity of the focused ultrasound, and prevent damage to a tissue other than a lesion to be removed.

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10-06-2021 дата публикации

CONTACT QUALITY ASSESSMENT BY DIELECTRIC PROPERTY ANALYSIS

Номер: US20210169602A1
Принадлежит: Navix International Limited

Devices and methods for assessing tissue contact based on dielectric properties and/or impedance sensing are disclosed. In some embodiments, one or more probing frequencies are delivered via electrodes including an electrode in proximity to a tissue (for example, myocardial tissue). In some embodiments, dielectric parameter values, optionally together with other known and/or estimated tissue characteristics, are measured to determine a contact quality with the tissue. In some embodiments, dielectric contact quality is used, for example, in guiding the formation of a lesion (for example, RF ablation of heart tissue to alter electrical transmission characteristics). 1. A system for evaluation of dielectric contact quality of an intra-body ablation probe with target tissue , the intra-body ablation probe including at least one electrode , and the system comprising:an electrical field measurement device, configured to measure dielectric properties in the environment of the at least one electrode using signals sensed by the at least one electrode at a plurality of electrical field frequencies; anda contact characterization module, comprising a data structure mapping the dielectric properties to characterization of contact, and configured to characterize contact between the intra-body ablation probe and the target tissue, based on the data structure and on the dielectric properties measured by the electrical field measurement device.2. The system of claim 1 , including the intra-body ablation probe.3. The system of claim 2 , wherein the intra-body probe comprises an ablation electrode configured for ablation of the target tissue.4. The system of claim 3 , wherein the at least one electrode comprises the ablation electrode.5. The system of claim 1 , comprising a display configured to display the characterized contact as an estimate of contact force.6. The system of claim 1 , wherein the electrical field measurement device comprises the at least one electrode.7. The system ...

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23-05-2019 дата публикации

Cryogenic Needle With Freeze Zone Regulation

Номер: US20190151006A1
Принадлежит: MyoScience Inc

A cryogenic needle of a cryogenic system is coupled to a heater. While the needle is inserted into target tissue beneath skin, the heater provides heat to protect the skin. Power supplied to the heater is used to interpolate performance of the needle and/or operating parameters of the cryogenic system.

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02-07-2015 дата публикации

Surgical generator for ultrasonic and electrosurgical devices

Номер: US20150182276A1
Принадлежит: Ethicon Endo Surgery Inc

A method for determining motional branch current in an ultrasonic transducer of an ultrasonic surgical device over multiple frequencies of a transducer drive signal. The method may comprise, at each of a plurality of frequencies of the transducer drive signal, oversampling a current and voltage of the transducer drive signal, receiving, by a processor, the current and voltage samples, and determining, by the processor, the motional branch current based on the current and voltage samples, a static capacitance of the ultrasonic transducer and the frequency of the transducer drive signal.

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02-07-2015 дата публикации

SURGICAL GENERATOR FOR ULTRASONIC AND ELECTROSURGICAL DEVICES

Номер: US20150182277A1
Принадлежит:

A method for determining motional branch current in an ultrasonic transducer of an ultrasonic surgical device over multiple frequencies of a transducer drive signal. The method may comprise, at each of a plurality of frequencies of the transducer drive signal, oversampling a current and voltage of the transducer drive signal, receiving, by a processor, the current and voltage samples, and determining, by the processor, the motional branch current based on the current and voltage samples, a static capacitance of the ultrasonic transducer and the frequency of the transducer drive signal. 1. A surgical system , comprising:a surgical device, wherein the surgical device comprises an end effector to treat tissue; provide a drive signal to drive the end effector;', 'receive a frequency of the drive signal; and', 'determine a temperature at the end effector considering the frequency of the drive signal., 'a surgical generator in communication with the surgical device, comprising at least one programmable logic device, wherein the at least one programmable logic device is programmed to2. The surgical system of claim 1 , wherein determining the temperature at the end effector comprises training a model of end effector temperature.3. The surgical system of claim 2 , wherein training the model comprises:providing to the model a set of input values including the frequency of the drive signal; andcomparing an output temperature of the model to a known output temperature associated with the set of input values.4. The surgical system of claim 1 , wherein the programmable logic device is further programmed to receive a plurality of input variables describing the end effector claim 1 , wherein the plurality of input variables comprises the frequency of the drive signal.5. The surgical system of claim 4 , wherein the plurality of input variables further comprises at least one of a voltage of the drive signal claim 4 , a current of the drive signal claim 4 , a power of the drive signal ...

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09-07-2015 дата публикации

Systems and Methods for Monitoring and Controlling Ultrasound Power Output and Stability

Номер: US20150190121A1
Принадлежит: Guided Therapy Systems LLC

Some embodiments provide a method of providing ultrasound energy having a stable power output. The method can comprise providing ultrasound energy from a ultrasound transducer; determining a power level threshold of the ultrasound energy; monitoring a power level of the ultrasound energy over time of the ultrasound energy; communicating a power level to a controller; adjusting the frequency of the ultrasound energy upon a change in the power level; and maintaining the power level threshold of the ultrasound energy.

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20-06-2019 дата публикации

Skin wrinkle treatment

Номер: US20190183562A1
Автор: Alan David Widgerow
Принадлежит: LIFE CARE MEDICAL DEVICES Ltd

A method for treating skin may first involve contacting an applicator of a skin heating device with an epidermal layer of the skin. The applicator may be activated to generate high-frequency alternating magnetic fields. The applicator may be used to heat a dermal layer of the skin, with the high-frequency alternating magnetic fields, to a temperature of less than 40 degrees Celsius, to stimulate a release of heat shock protein in the dermal layer to promote collagen generation. The method may also involve limiting heating of the dermal layer of the skin to less than 40 degrees Celsius.

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27-07-2017 дата публикации

Temperature controlled short duration ablation

Номер: US20170209209A1
Принадлежит: Biosense Webster Israel Ltd

A method, including selecting a first maximum radiofrequency (RF) power to be delivered by an electrode within a range of 70 W-100 W, and selecting a second maximum RF power to be delivered by the electrode within a range of 20 W-60 W. The method also includes selecting an allowable force on the electrode within a range of 5 g-50 g, selecting a maximum allowable temperature, of tissue to be ablated, within a range of 55° C.-65° C., and selecting an irrigation rate for providing irrigation fluid to the electrode within a range of 8-45 ml/min. The method further includes performing an ablation of tissue using the selected values by initially using the first power, switching to the second power after a predefined time between 3 s and 6 s, and terminating the ablation after a total time for the ablation between 10 s and 20 s.

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25-06-2020 дата публикации

APPARATUS FOR EFFECTIVE ABLATION AND NERVE SENSING ASSOCIATED WITH DENERVATION

Номер: US20200197079A1
Принадлежит:

An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes at the distal ends of the guide tubes allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered to ablate nerves outside of the media. 121-. (canceled)22. A method comprising:inserting a distal end of a catheter body into a patient, the catheter body having a proximal end and a connector configured to connect to external electronic equipment outside the catheter body;moving at least two elements outwardly from the catheter body toward an interior wall of a target vessel, a first element of the at least two elements comprising a first distal electrode, a second element of the at least two elements comprising a second distal electrode, wherein the at least two elements have a blunt, non-beveled tip which is atraumatic to the interior wall of the target vessel, wherein the at least two elements are configured to maintain their position against the interior wall of the target vessel;sensing nerve activity between the first distal electrode and the second distal electrode; andconducting electrical signals from the first distal electrode and the second distal electrode to the connector for communicating with the external electronic equipment.23. The method of claim 22 , further ...

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04-07-2019 дата публикации

Electrosurgical instrument

Номер: US20190201095A1
Принадлежит: Creo Medical Ltd

An electrosurgical instrument with a radiating tip portion having a relative permeability and/or relative permittivity that is selected to provide an electrical length for the radiating tip portion that enables effective delivery into biological tissue of microwave EM energy supplied thereto, at two or more frequencies of choice. The instrument has a radiating tip portion disposed to receive microwave EM energy from a coaxial cable, the radiating tip portion having a first effective relative permeability at a first frequency and a second effective relative permeability at a second frequency.

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03-08-2017 дата публикации

Optimizing Treatment Using TTfields by Changing the Frequency During the Course of Long Term Tumor Treatment

Номер: US20170215939A1
Автор: DISHON Matan, PALTI Yoram
Принадлежит: Novocure Limited

Tumors can be treated with an alternating electric field. The size of cells in the tumor is determined prior to the start of treatment by, for example, biopsy or by inverse electric impedance tomography. A treatment frequency is chosen based on the determined cell size. The cell size can be determined during the course of treatment and the treatment frequency is adjusted to reflect changes in the cell size. A suitable apparatus for this purpose includes a device for measuring the tumor impedance, an AC signal generator with a controllable output frequency, a processor for estimating the size of tumor cells and setting the frequency of the AC signal generator based thereon, and at least one pair of electrodes operatively connected to the AC signal generator such that an alternating electric field is applied to the tumor. 1. A method for adaptively treating a tumor with an alternating electric field , the method comprising the steps of:applying an alternating electric field having a first frequency to the tumor for a first duration;determining an impedance of the tumor based on a measured current during the first duration while the alternating electric field having the first frequency is applied;estimating a size of cells in the tumor based on the determined impedance;selecting a second frequency based on the estimated size of cells; andapplying an alternating electric field to the tumor at the second frequency to treat the tumor.2. The method of claim 1 , further comprising the steps of:waiting for a period of time;applying an alternating electric field having a third frequency to the tumor;determining a second impedance of the tumor based on a measured current while the alternating electric field having the third frequency is applied;estimating a second size of cells in the tumor based on the determined second impedance; selecting a fourth frequency based on the estimated second size of cells; andapplying an alternating electric field to the tumor at the fourth ...

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04-07-2019 дата публикации

VARIABLE FREQUENCY EXCITATION PLASMA DEVICE FOR THERMAL AND NON-THERMAL TISSUE EFFECTS

Номер: US20190208614A1
Принадлежит:

A plasma system is disclosed. The plasma system includes a plasma instrument having an elongated body defining a lumen therethrough and a first electrode and a second electrode; an ionizable media source in fluid communication with the lumen and configured to supply ionizable media thereto; and a variable frequency energy source adapted to be coupled to the first and second electrodes and configured to supply energy to the first and second electrodes sufficient to ignite ionizable media supplied by the ionizable media source to generate a plasma influent, wherein a frequency of the energy is adjustable to modify at least one property of the plasma effluent. 120-. (canceled)21. A plasma system comprising:a plasma instrument;an ionizable media source in fluid communication with the plasma instrument and configured to supply ionizable media thereto; and supply an excitation waveform including a plurality of cycles to the plasma instrument sufficient to ignite the ionizable media supplied by the ionizable media source to generate a plasma effluent; and', 'adjust a frequency of the excitation waveform on a cycle-by-cycle basis to a first frequency at which the plasma effluent is at a first temperature for non-thermal treatment of tissue and a second frequency, higher than the first frequency, at which the plasma effluent is at a second temperature, higher than the first temperature, for thermal treatment of tissue., 'a variable frequency energy source coupled to the plasma instrument and configured to22. The plasma system according to claim 21 , wherein the ionizable media source is adapted to be coupled to the variable frequency energy source.23. The plasma system according to claim 22 , wherein the variable frequency energy source is configured to adjust the frequency based on a flow rate of the ionizable media from the ionizable media source.24. The plasma system according to claim 21 , wherein the plasma instrument includes:an elongated body defining a lumen ...

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02-07-2020 дата публикации

Improved laser-therapy device

Номер: US20200206528A1
Автор: Michele Gallamini
Принадлежит: Fremslife Srl

An improved laser-therapy device for the treatment of acupuncture points, which comprises: a control unit; laser emitting means associated to said control unit; means for generating an emission signal, which are functionally associated to said control unit and to said laser emitting means; and means for modulating said emission signal, which are designed to generate a modulated signal, wherein said modulated signal derives from a first square-wave modulation at a frequency of 100 Hz combined with a second square-wave modulation at a frequency of between 1 and 2 Hz, characterized in that a third square-wave modulation at a frequency of between 50 and 200 Hz is provided, combined, respectively, with said first and second modulations, characterized in that a third square-wave modulation at a frequency of between 5 and 20 Hz is provided, combined, respectively, with said first and second modulations.

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18-07-2019 дата публикации

Techniques for predicting recurrence of cancerous cells using impedance detection

Номер: US20190216358A1
Автор: William David Gregory
Принадлежит: NovaScan Inc

One embodiment of the present application sets forth a method for predicting recurrence of cancerous cells in a patient that includes measuring, by a first subset of electrodes included in an electrode array operating at a first frequency, a first impedance of a first section of a first sample of tissue excised from the patient, computing a first Cole relaxation frequency for the first section of the first sample based on the first impedance, and generating a first prediction relating to cancerous cells in the patient based at least in part on the first Cole relaxation frequency.

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19-08-2021 дата публикации

Microwave system for global endometrial ablation

Номер: US20210251689A1
Принадлежит: Hologic Inc, Kansas State University

A tissue ablation system includes an antenna, a microwave energy source, measurement apparatus including a signal generator and a detector, a controller, and a switch assembly arranged to alternatively electrically couple the antenna to the microwave energy source or to the measurement apparatus, wherein the controller is configured to cause the switch assembly to alternate between assessment mode and ablation mode, and wherein the controller is configured to control the delivery of ablative microwave energy during an ablation mode based at least in part on a difference between a then-current broadband reflection coefficient spectrum and a previously measured broadband reflection coefficient spectrum obtained by delivery of a spectrum of individual non-ablative microwave signals and detecting the reflection of same during respective assessment modes.

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25-07-2019 дата публикации

Device and methods for delivery of high frequency electrical pulses for non-thermal ablation

Номер: US20190223938A1

The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative disorders are provided. In embodiments, the methods comprise the delivery of high-frequency bursts of bipolar pulses to achieve the desired modality of cell death. More specifically, embodiments of the invention relate to a device and method for destroying aberrant cells, including tumor tissues, using high-frequency, bipolar electrical pulses having a burst width on the order of microseconds and duration of single polarity on the microsecond to nanosecond scale. In embodiments, the methods rely on conventional electroporation with adjuvant drugs or irreversible electroporation to cause cell death in treated tumors. The invention can be used to treat solid tumors, such as brain tumors.

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06-11-2014 дата публикации

OPTIMIZING TREATMENT USING TTFIELDS BY CHANGING THE FREQUENCY DURING THE COURSE OF LONG TERM TUMOR TREATMENT

Номер: US20140330268A1
Автор: DISHON Matan, PALTI Yoram
Принадлежит: NOVOCURE LTD

Tumors can be treated with an alternating electric field. The size of cells in the tumor is determined prior to the start of treatment by, for example, biopsy or by inverse electric impedance tomography. A treatment frequency is chosen based on the determined cell size. The cell size can be determined during the course of treatment and the treatment frequency is adjusted to reflect changes in the cell size. A suitable apparatus for this purpose includes a device for measuring the tumor impedance, an AC signal generator with a controllable output frequency, a processor for estimating the size of tumor cells and setting the frequency of the AC signal generator based thereon, and at least one pair of electrodes operatively connected to the AC signal generator such that an alternating electric field is applied to the tumor. 1. A method for adaptively treating a tumor with an alternating electric field , the method comprising the steps of:applying an alternating electric field having a first frequency to the tumor;determining an impedance of the tumor based on a measured current while the alternating electric field having the first frequency is applied;estimating a size of cells in the tumor based on the determined impedance;selecting a second frequency based on the estimated size of cells; andapplying an alternating electric field to the tumor at the second frequency to treat the tumor.2. The method of claim 1 , further comprising the steps of:waiting for a period of time;applying an alternating electric field having a third frequency to the tumor;determining a second impedance of the tumor based on a measured current while the alternating electric field having the third frequency is applied;estimating a second size of cells in the tumor based on the determined second impedance;selecting a fourth frequency based on the estimated second size of cells; andapplying an alternating electric field to the tumor at the fourth frequency to treat the tumor.3. The method of claim ...

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09-09-2021 дата публикации

Methods of detecting and treating back pain

Номер: US20210275245A1
Принадлежит: Relievant Medsystems Inc

Described herein are various implementations of systems and methods for accessing and modulating tissue (for example, systems and methods for accessing and ablating nerves or other tissue within or surrounding a vertebral body to treat chronic lower back pain). Assessment of vertebral endplate degeneration or defects (e.g., pre-Modic changes) to facilitate identification of treatment sites and protocols are also provided in several embodiments. Several embodiments comprise the use of biomarkers to confirm or otherwise assess ablation, pain relief, efficacy of treatment, etc. Some embodiments include robotic elements for, as an example, facilitating robotically controlled access, navigation, imaging, and/or treatment.

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07-09-2017 дата публикации

METHODS AND APPARATUS FOR REDUCING SWEAT PRODUCTION

Номер: US20170252105A1
Принадлежит:

Methods and apparatuses are provided for reducing sweat production via, for example, the removal, disablement, and incapacitation of sweat glands in the epidermis, dermis and subdermal tissue regions of a patient. In one embodiment, a method of treating a patient is provided which involves identifying a patient having a condition of excessive sweating, positioning an energy delivery device proximate to a skin tissue of the patient and delivering energy to sweat glands to halt secretion of sweat. The energy delivery device may include microwave delivery devices, RF delivery devices, and cryogenic therapy devices. Some embodiments may include using a cooling element for avoiding destruction of non-target tissue and/or a suction device to localize treatment at specific portions of the skin fold. 1. A method of treating a patient comprising:identifying an area of skin tissue comprising a layer of sweat glands, wherein the area of skin tissue produces sweat;grasping the area of skin tissue, wherein, the layer of sweat glands comprise a treatment zone;applying protective cooling with a cooling element to at least a portion of the area of skin tissue;positioning microwave antennas adjacent to the treatment zone; anddelivering microwave energy with the microwave antennas through the cooling element to the treatment zone to yield a treatment effect, the treatment effect reducing the amount of sweating from the area of skin tissue.2. The method of claim 1 , wherein the area of skin tissue comprises at least a portion of the axilla.3. The method of claim 1 , wherein applying protective cooling to at least a portion of the area of skin tissue further comprises positioning the cooling element proximate the area of skin tissue.4. The method of claim 1 , wherein grasping the area of skin tissue further comprises providing suction to the area of skin tissue.5. The method of claim 4 , wherein providing suction to the area of skin tissue further comprises maintaining suction to the ...

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13-09-2018 дата публикации

Electrosurgical system

Номер: US20180256240A1
Принадлежит: MEDTRONIC INC

An electrosurgical system includes a radiofrequency (RF) generator having a controller configured to detect an occurrence of a vaporization point of target tissue and a vaporization duration between commencement of delivery of the RF energy and the occurrence of the vaporization point. The controller can apply the vaporization duration to adjust a parameter during subsequent electrode activation, such as RF power level, an electrode activation sequence, a distance between activated electrodes, and a number of activated electrodes. The controller can apply the vaporization duration to determine if whether a predetermined depth of effect has been reached for use in subsequent parameter adjustments.

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20-09-2018 дата публикации

SYSTEM AND METHOD FOR DRIVING AN ULTRASONIC HANDPIECE AS A FUNCTION OF THE MECHANICAL IMPEDANCE OF THE HANDPIECE

Номер: US20180263652A1
Автор: Downey Adam, Owen Matthew
Принадлежит: STRYKER CORPORATION

An ultrasonic surgical tool system for actuating a handpiece with a tip. The frequency of the drive signal applied to the handpiece drivers is a function of the equivalent of current through the mechanical components of the handpiece and tip and the frequency responsiveness of these components. 1. A system for vibrating the tip of an ultrasonic handpiece , the handpiece having an at least one driver to which an AC drive signal is applied to vibrate the tip , the system including:a control console for generating the AC drive signal that is applied to the handpiece;a sensor for measuring a voltage of the AC drive signal;a sensor for measuring a current of the AC drive signal; and based on the voltage of the AC drive signal, the current of the AC drive signal, the frequency of the AC drive signal and the capacitance of the at least one driver, calculate current applied to the at least one driver and the equivalent of current applied to the mechanical components of the handpiece;', 'calculate a value based on the current applied to the at least one driver and the equivalent of current applied to the mechanical components of the handpiece; and', 'based on the calculated value, set the frequency of the AC drive signal output by the control console., 'a processor coupled to the sensors for measuring the voltage and current of the AC drive signal and configured to2. The system of further comprising the handpiece having at least one driver coupled to the control console.3. The system of claim 1 , wherein said processor is configured to calculate the equivalent of current applied to the mechanical components of the handpiece by determining the difference in the current of the AC drive signal and the current through the at least one driver.3. The system of claim 3 , wherein said processor is configured to determine the current through the at least one driver as function of the capacitance of the at least one driver and the voltage and frequency of the AC drive signal.4. The ...

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29-08-2019 дата публикации

CRYOTHERAPY, THERMAL THERAPY, TEMPERATURE MODULATION THERAPY, AND PROBE APPARATUS THEREFOR

Номер: US20190262057A1
Автор: GRANT Mark A., TYC Richard
Принадлежит:

A variable length interstitial probe apparatus includes: a probe for effecting thermal therapy and/or cryotherapy to a tissue; a flexible umbilical sheath permanently affixed to the probe, including at least one interface for supplying energy, cooling fluid, cooling gas, heating fluid, and/or heating gas to the probe; and an adjustable depth stop configured to slide along a length of a shaft region of the probe, and lock to the shaft region at a selected position. The adjustable depth stop is configured to engage a probe driver and/or a skull mount apparatus to stabilize positioning of the probe and to control a depth of entry of the probe into a patient. The probe may be configured to effect temperature modulation therapy, where processing circuitry activates a modulation pattern of thermal therapy emission and cryogenic therapy emission for applying a thermal dose to the tissue. 1. A system for performing temperature modulation therapy to a tissue with an interstitial probe , the system comprising:an interstitial probe, comprising a shaft region, a tip region, at least one thermal therapy-generating element for thermal therapy emission via the tip region, and at least one cryotherapy-generating element for cryogenic therapy emission via the tip region;processing circuitry; and activate temperature modulation therapy by the interstitial probe utilizing a modulation pattern of thermal therapy emission and cryogenic therapy emission for applying a thermal dose to the tissue,', 'wherein the modulation pattern comprises at least one higher thermal output corresponding to activation of a first thermal therapy element of the at least the thermal therapy-generating element for a first time interval, and at least one lower thermal output corresponding to activation of a first cryogenic therapy element of the at least one cryogenic therapy element for a second time interval different than the first time interval,', 'wherein prior to activating the temperature modulation ...

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06-10-2016 дата публикации

CRYOTHERAPY, THERMAL THERAPY, TEMPERATURE MODULATION THERAPY, AND PROBE APPARATUS THEREFOR

Номер: US20160287308A1
Принадлежит: MONTERIS MEDICAL CORPORATION

A variable length interstitial probe apparatus includes: a probe for effecting thermal therapy and/or cryotherapy to a tissue; a flexible umbilical sheath permanently affixed to the probe, including at least one interface for supplying energy, cooling fluid, cooling gas, heating fluid, and/or heating gas to the probe; and an adjustable depth stop configured to slide along a length of a shaft region of the probe, and lock to the shaft region at a selected position. The adjustable depth stop is configured to engage a probe driver and/or a skull mount apparatus to stabilize positioning of the probe and to control a depth of entry of the probe into a patient. The probe may be configured to effect temperature modulation therapy, where processing circuitry activates a modulation pattern of thermal therapy emission and cryogenic therapy emission for applying a thermal dose to the tissue. 1. A variable length interstitial probe apparatus for effecting treatment to a tissue , comprising:a probe portion for effecting at least one of thermal therapy and cryotherapy to the tissue;a flexible umbilical sheath portion permanently affixed to the probe portion, wherein the flexible umbilical sheath portion includes at least one interface for supplying one of energy, cooling fluid, cooling gas, heating fluid, and heating gas to the probe portion; and slideably move along a length of a shaft region of the probe portion, and', 'releasably lock to the shaft region of the probe portion at a selected position;, 'an adjustable depth stop configured to'}wherein the adjustable depth stop includes a releasably engageable fastener configured to engage at least one of a probe driver and a skull mount apparatus to stabilize positioning of the probe portion and to control a depth of entry of the probe portion into a patient.2. The variable length interstitial probe apparatus of claim 1 , wherein the shaft region comprises a plurality of gradation markings for selecting a measurement correlating ...

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06-10-2016 дата публикации

INTERDIGITATION OF WAVEFORMS FOR DUAL-OUTPUT ELECTROSURGICAL GENERATORS

Номер: US20160287311A1
Автор: FRIEDRICHS Daniel A.
Принадлежит:

Disclosed are systems, devices, and methods for interdigitation of waveforms for dual-output electrosurgical generators. Such methods may comprise outputting DC energy from a power supply, converting DC energy from the power supply, by a plurality of amplifiers coupled to the power supply, into a plurality of RF waveforms, and controlling the plurality of RF amplifiers to interdigitate the first and second RF waveforms. 1. An electrosurgical generator , comprising:a power supply configured to output DC energy;a plurality of RF amplifiers coupled to the power supply, each of the plurality of RF amplifiers being configured to convert DC energy from the power supply into an RF waveform, thereby generating a plurality of RF waveforms; anda controller coupled to the power supply and the plurality of RF amplifiers and configured to control the plurality of RF amplifiers to interdigitate the RF waveforms generated by the plurality of RF amplifiers.2. The electrosurgical generator according to claim 1 , further comprising a plurality of sensors coupled to the plurality of RF amplifiers claim 1 , each of the plurality of sensors configured to measure at least one property of a corresponding RF waveform of the plurality of RF waveforms supplied by a corresponding RF amplifier of the plurality of RF amplifiers.3. The electrosurgical generator according to claim 2 , wherein the controller is further coupled to the plurality of sensors and is further configured to control the plurality of RF amplifiers based on the at least one property of the corresponding RF waveform.4. The electrosurgical generator according to claim 1 , wherein the plurality of RF waveforms are square waveforms.5. The electrosurgical generator according to claim 1 , wherein the controller is further configured to adjust the DC energy supplied by the power supply to the plurality of RF amplifiers based on at least one property of at least one RF waveform of the plurality of RF waveforms.6. The electrosurgical ...

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05-10-2017 дата публикации

Surgical resection apparatus

Номер: US20170281272A1
Принадлежит: Creo Medical Ltd

Surgical cutting apparatus having a treatment channel and a measurement channel for conveying microwave energy from a source to an antenna at a cutting edge. The measurement channel operates at lower power than the treatment channel for determining when higher energy can be safely applied. The apparatus may deliver microwave radiation at differing frequencies to one or more antennas at the cutting edge, e.g. to provide different treatment effects. The source may generate an output for an antenna whose frequency can be selected e.g. for most efficient operation. Selection may be automatic based on detected magnitude and phase of reflected signals during a frequency sweep of a forward signal. Power delivered to tissue via the cutting element may be manually boosted to deal with large blood vessels. The apparatus may include a reflected power monitor for recognising behaviour in reflected signals received from the antenna to trigger automatic pre-emptive action.

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22-10-2015 дата публикации

Methods and systems for treatment of tissue in a body lumen

Номер: US20150297293A1
Принадлежит: COVIDIEN LP

A system for measuring physiologic characteristics or treating tissue in a body lumen. The system may be used for treating abnormal mucosa in the esophagus. The system comprises an energy delivery device, such as an ablation device including an electrode support and an electrode pattern on the support. The ablation device may expand in size from a pre-deployed state to a deployed state. The system may include a sizing device having an inflatable balloon on a distal end of a catheter that is inflated with an expansion medium to expand the balloon to engage the wall of the esophagus so that the internal cross-section can be calculated or measured. The sizing device may also a controller for delivering an expansion medium and measuring the amount and pressure of the expansion medium inside the catheter. Methods of treating or diagnosing tissue are also disclosed.

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19-10-2017 дата публикации

Anchored RF Ablation Device for The Destruction of Tissue Masses

Номер: US20170296256A9
Принадлежит: HALT MEDICAL INC.

The inventive ablation element comprises an elongated cannula having a proximal end and a distal end. The cannula defines an internal lumen and a cannula axis. A plurality of conductors contained within the lumen, each having a proximal end proximate the proximal end of the cannula, and a distal end proximate the distal end of the cannula. A plurality of ablation stylets each has a proximal end and a distal end, and each coupled to the distal end of a respective conductor, the conductors together with their respective stylets being mounted for axial movement. A trocar point defined proximate the distal end of the cannula. A deflection surface positioned between the trocar point and the proximal end of the cannula, the deflection surface being configured and positioned to deflect at least some of the stylets laterally with respect to the cannula axis in different directions defining an ablation volume. 1. An ablation element , comprising:(a) an elongated cannula having a proximal end and a distal end, said cannula defining an internal lumen within said cannula and a cannula axis;(b) a plurality of conductors contained within said lumen, each of said conductors having a proximal end proximate the proximal end of said cannula, and a distal end proximate the distal end of said cannula;(c) a plurality of ablation stylets each having a proximal end and a distal end, and each coupled at the respective proximal end of said stylet to the distal end of a respective conductor, said stylets comprising a deflectable material, said conductors together with their respective stylets being mounted for axial movement;(d) a trocar point defined proximate the distal end of said cannula; and(e) a deflection surface positioned between said trocar point and said proximal end of said cannula, the deflection surface being configured and positioned to deflect, in response to axial movement of said stylets in a direction from said proximate end of said cannula to said distal end of said ...

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25-10-2018 дата публикации

SURGICAL LASER SYSTEMS AND LASER LITHOTRIPSY TECHNIQUES

Номер: US20180303549A1
Принадлежит: BOSTON SCIENTIFIC SCIMED, INC.

A surgical laser system () includes a first laser source (A), a second laser source (B), a beam combiner () and a laser probe (). The first laser source is configured to output a first laser pulse train (A) comprising first laser pulses (). The second laser source is configured to output a second laser pulse train (B) comprising second laser pulses (). The beam combiner is configured to combine the first and second laser pulse trains and output a combined laser pulse train () comprising the first and second laser pulses. The laser probe is optically coupled to an output of the beam combiner and is configured to discharge the combined laser pulse train. 120.-. (canceled)21. A system comprising:a first laser generator configured to generate a first laser pulse train having first laser pulses with a first pulse repetition rate;an analyzer configured to receive a portion of the first laser pulse train reflected from a kidney or bladder stone, and generate an output relating to a natural or resonance frequency of the kidney or bladder stone; anda controller configured to determine the natural or resonance frequency of the kidney or bladder stone based on the output from the analyzer, and match the first pulse repetition rate with the natural or resonance frequency.22. The system of claim 21 , further comprising a laser probe configured to discharge the first laser pulse train towards the kidney or bladder stone.23. The system of claim 21 , further including a second laser generator configured to generate a second laser pulse train having second laser pulses with a second pulse repetition rate.24. The system of claim 23 , wherein the second laser pulses have a lower energy level than the first laser pulses.25. The system of claim 23 , wherein the first pulse repetition rate is different than the second pulse repetition rate.26. The system of claim 23 , wherein each second laser pulse in the second laser pulse train includes a pulse width less than 1 millisecond.27. The ...

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12-11-2015 дата публикации

ELECTROSURGICAL GENERATOR

Номер: US20150320479A1
Автор: Cosman, JR. Eric R.
Принадлежит: Chenes LLC

This invention relates to high-frequency ablation of tissue in the body using a cooled high-frequency electrode connected to a high frequency generator including a computer graphic control system and an automatic controller for control the signal output from the generator, and adapted to display on a real time graphic display a measured parameter related to the ablation process and visually monitor the variation of the parameter of the signal output that is controlled by the controller during the ablation process. In one example, one or more measured parameters are displayed simultaneously to visually interpret the relation of their variation and values. In one example, the displayed one or more parameters can be taken from the list of measured voltage, current, power, impedance, electrode temperature, and tissue temperature related to the ablation process. The graphic display gives the clinician an instantaneous and intuitive feeling for the dynamics and stability of the ablation process for safety and control. This invention relates to monitoring and controlling multiple ground pads to optimally carry return currents during high-frequency tissue ablation, and to prevent of ground-pad skin burns. This invention relates to the use of ultrasound imaging intraoperatively during a tissue ablation procedure. This invention relates to the use of nerve stimulation and blocking during a tissue ablation procedure. 1. A system for tissue ablation that includes a radiofrequency signal generator , a controller , an ablation electrode , and at least two ground pads; wherein the controller automatically generates a sequence of at least two configurations; wherein , in a first configuration having a first duration , both a first ground pad and a second ground pad are connected to the radiofrequency signal generator , and current generated by the radiofrequency signal generator flows from the ablation electrode to both the first ground pad and the second ground pad through a ...

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12-11-2015 дата публикации

Electrosurgical generator

Номер: US20150320481A1
Принадлежит: Chenes LLC

This invention relates to high-frequency ablation of tissue in the body using a cooled high-frequency electrode connected to a high frequency generator including a computer graphic control system and an automatic controller for control the signal output from the generator, and adapted to display on a real time graphic display a measured parameter related to the ablation process and visually monitor the variation of the parameter of the signal output that is controlled by the controller during the ablation process. In one example, one or more measured parameters are displayed simultaneously to visually interpret the relation of their variation and values. In one example, the displayed one or more parameters can be taken from the list of measured voltage, current, power, impedance, electrode temperature, and tissue temperature related to the ablation process. The graphic display gives the clinician an instantaneous and intuitive feeling for the dynamics and stability of the ablation process for safety and control. This invention relates to monitoring and controlling multiple ground pads to optimally carry return currents during high-frequency tissue ablation, and to prevent of ground-pad skin burns. This invention relates to the use of ultrasound imaging intraoperatively during a tissue ablation procedure. This invention relates to the use of nerve stimulation and blocking during a tissue ablation procedure.

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02-11-2017 дата публикации

Visualization apparatus for property change of a tissue

Номер: US20170311922A1
Принадлежит: Koninklijke Philips NV

The present invention relates to a visualization apparatus ( 1 ) comprising a signal processor ( 2 ) for processing measurement signals from an ultrasound measurement ( 3 ) and a rendering device ( 4 ) coupled to a processor for rendering a representation for discerning a region of tissue with changed property ( 42 ) upon energy application to the tissue from a region with unchanged property ( 41 ) within two extremities ( 44,47 ) of the representation indicative of two boundaries defining the tissue thickness. The rendering of the tissue with changed property ( 42 ) and the tissue with unchanged property ( 41 ) with different visual aspects is readily absorbable by a person who applies energy to the tissue.

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09-11-2017 дата публикации

RADIO FREQUENCY SKIN TREATMENT

Номер: US20170319262A1
Принадлежит:

A device for radio frequency (RF) skin treatment of skin of a user is provided. The device comprises an active electrode and a return electrode. The device further comprises an RF generator arranged to supply RF energy to the user's skin via the active electrode and the return electrode. The return electrode has a planar skin contact surface extending in a main plane. The active electrode has a skin contact surface with a maximum dimension in a range from 100 μm to 500 μm, and a surface area of the planar skin contact surface of the return electrode is at least 5 times larger than a surface area of the skin contact surface of the active electrode. The skin contact surface of the active electrode is arranged in a position at a distance from the main plane, seen in a direction perpendicular to the main plane. The device may be advantageously used, for example, to control the dimensions and shape of a thermal lesion in the user's skin generated by the RF energy. 2. The device according to claim 1 , wherein the distance is larger than 0.5 mm.3. The device according to claim 1 , wherein the skin contact surface of the active electrode has a circular circumference with a diameter in a range from 100 μm to 500 μm.4. The device according to claim 1 , wherein the return electrode surrounds the active electrode.5. The device according to claim 4 , wherein the planar skin contact surface of the return electrode is annular claim 4 , and wherein the active electrode is arranged on a center line of the planar skin contact surface.6. The device according to claim 5 , wherein the planar skin contact surface has an inside diameter between 1 and 4 mm and a radial width between 1 and 5 mm.7. The device according to claim 1 , wherein an outer surface of the device comprises a protrusion claim 1 , wherein the active electrode is arranged on top of the protrusion claim 1 , and wherein the return electrode is arranged adjacent to the protrusion.8. The device according to claim 7 , wherein ...

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08-11-2018 дата публикации

System and Method for Determining Ablation Parameters

Номер: US20180318013A1
Принадлежит: St Jude Medical Cardiology Division Inc

Parameters for cardiac ablation can be determined using a map of one or more biological properties of a tissue to be ablated, such as tissue thickness. The biological properties are used to compute a transmurality index map. In turn, the transmurality index map can be used to determine one or more of ablation energy level, ablation time, and ablation contact force to achieve a transmural lesion. Graphical representations of the biological property maps, the transmural index map, and/or the ablation parameters can be output, for example on geometric models of the heart and/or the ablation catheter.

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16-11-2017 дата публикации

ABLATION DEVICES WITH DUAL OPERATING FREQUENCIES, SYSTEMS INCLUDING SAME, AND METHODS OF ADJUSTING ABLATION VOLUME USING SAME

Номер: US20170325871A1
Автор: Brannan Joseph D.
Принадлежит:

An ablation device includes a feedline including an inner conductor having a distal end, an outer conductor coaxially disposed around the inner conductor, and a dielectric material disposed therebetween, an elongated electrically-conductive member longitudinally disposed at the distal end of the inner conductor and having a proximal end, a first balun structure disposed over a first portion of the outer conductor and positioned so that a distal end of the first balun structure is located at a first distance from the proximal end of the electrically-conductive member and a second balun structure disposed over a second portion of the outer conductor and positioned so that a distal end of the second balun structure is located at a second distance from the proximal end of the electrically-conductive member. 120-. (canceled)21. A method of adjusting an ablation volume , the method comprising:positioning an ablation device within tissue, the ablation device including an inner conductor surrounded by an outer conductor;delivering energy to tissue via the inner and outer conductors;controlling the energy to a first operating frequency operably associated with a first balun structure disposed on the outer conductor; andcontrolling the energy to a second operating frequency different than the first operating frequency, the second operating frequency operably associated with a second balun structure disposed on the outer conductor in spaced relation to the first balun structure.22. The method according to claim 21 , further comprising directing the energy to at least one of the first or second balun structures via a dielectric layer coaxially disposed around the outer conductor.23. The method according to claim 22 , wherein the dielectric layer extends distally beyond a distal-most end of the inner conductor.24. The method according to claim 21 , wherein delivering energy to tissue further comprises delivering energy to an electrically conductive element extending distally ...

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16-11-2017 дата публикации

SURGICAL LASER SYSTEMS AND LASER LITHOTRIPSY TECHNIQUES

Номер: US20170325890A1
Принадлежит:

A system may include a stone analyzer, a controller, a laser generator, and a beam combiner. The stone analyzer may be configured to generate an output relating to a natural or resonance frequency of a kidney or bladder stone. The controller may be configured to determine the natural or resonance frequency of the stone based on the output from the stone analyzer, and match a resultant pulse repetition rate with the natural or resonance frequency. The laser generator may be configured to generate at least two laser pulse trains, with each laser pulse train including laser pulses at a pulse repetition rate. The beam combiner may be configured to combine the at least two laser pulse trains into a combined laser pulse train including laser pulses at the resultant pulse repetition rate. 120.-. (canceled)21. A system comprising:a stone analyzer configured to generate an output relating to a natural or resonance frequency of a kidney or bladder stone;a controller configured to determine the natural or resonance frequency of the stone based on the output from the stone analyzer, and match a resultant pulse repetition rate with the natural or resonance frequency;a laser generator configured to generate at least two laser pulse trains, each laser pulse train including laser pulses at a pulse repetition rate; anda beam combiner configured to combine the at least two laser pulse trains into a combined laser pulse train including laser pulses at the resultant pulse repetition rate.22. The system of claim 21 , further comprising a laser probe configured to discharge the combined laser pulse train towards the kidney or bladder stone.23. The system of claim 21 , wherein each of the at least two laser pulse trains includes laser energy at a different wavelength.24. The system of claim 21 , wherein each of the at least two laser pulse trains includes laser energy at a different power level.25. The system of claim 21 , wherein the pulse repetition rate of each of the at least two ...

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08-10-2020 дата публикации

ENERGY TREATMENT DEVICE AND METHOD FOR MANUFACTURING ENERGY TREATMENT DEVICE

Номер: US20200315696A1
Автор: AKAGANE Tsunetaka
Принадлежит: OLYMPUS CORPORATION

An energy treatment device includes: a base having electrical conductivity and including a treatment surface for applying a high-frequency current to a treatment target when being supplied with electrical energy. A coating, including a silane coupling agent having a coupling structure, is formed over at least the treatment surface of the base by a bond due to the coupling structure; and an organic layer is disposed between the treatment surface of the base and the coating, and is bonded to the surface of the base. The coupling structure of the coupling agent of the coating is bonded to the organic layer. 1. An energy treatment device comprising:a base having electrical conductivity and including a treatment surface configured to apply a high-frequency current to a treatment target when supplied with electrical energy;a coating including a silane coupling agent having a coupling structure, the coating being formed over at least the treatment surface of the base by a bond due to the coupling structure; andan organic layer that is disposed between the treatment surface of the base and the coating, and is bonded to the treatment surface of the base,wherein the coupling structure of the coupling agent of the coating is bonded to the organic layer.2. The energy treatment device according to claim 1 , wherein the coupling agent of the coating includes a molecular chain having carbon and fluorine3. The energy treatment device according to claim 1 , wherein the silane coupling agent of the coating includes the coupling structure at both ends of a molecular chain.4. The energy treatment device according to claim 1 , wherein the base is formed of a titanium alloy.5. The energy treatment device according to claim 1 , wherein the organic layer includes a titanate coupling agent having a coupling structure claim 1 , and the coupling structure of the titanate coupling agent is bonded to the treatment surface of the base.6. The energy treatment device according to claim 1 , wherein ...

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03-12-2015 дата публикации

Epilation by Thermolysis

Номер: US20150342666A1
Автор: Suzanne Anderer
Принадлежит: Individual

A method for removing hair by thermolysis is provided. The method steps include oscillating a direct current to create an alternating current (“AC”) micro-pulse, pulsing the AC micro-pulse on and off continuously, delivering the AC micro-pulse to a probe, applying the probe to a hair follicle, and inverting the direction of the AC micro-pulse on the hair follicle. When the probe is applied to the hair follicle, the AC micro-pulse travels from the top of the dermis of the hair follicle to a dermal papilla of the hair follicle. The AC micro-pulse reverses direction at the dermal papilla and travels to the top of the dermis of the hair follicle. The AC micro-pulse produces heat that destroys the tissues controlling the growth of the hair follicle.

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23-11-2017 дата публикации

APPARATUS FOR EFFECTIVE ABLATION AND NERVE SENSING ASSOCIATED WITH DENERVATION

Номер: US20170332926A1
Принадлежит:

An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes near the distal ends of the needles allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media. 121-. (canceled)22. A method of treating hypertension , comprising:positioning a distal portion of a denervation catheter within a renal artery of a human patient;advancing at least two needle guiding elements outward from the catheter toward an inside surface of the renal artery;advancing at least a first conducting injection needle and a second conducting injection needle through the first and second needle guiding elements and into a peri-vascular space outside of the inside surface of the renal artery;operating the catheter to provide at least one modality of neurolysis to sympathetic nerves located in the peri-vascular space; andsensing nerve activity from at least one of the first and second conducting injection needles from locations outside of the renal artery.23. The method of treating hypertension as in claim 22 , wherein the at least one modality of ablation includes injecting an ablative fluid through the first and second conducting injection needles to form ...

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23-11-2017 дата публикации

Catheter extension control

Номер: US20170333104A1
Принадлежит: Individual

The present disclosure pertains to devices and methods for diagnosis and treatment of biological tissue in which the tissue is accessed by a catheter through a working channel of an endoscope and in which the degree of extension of a distal tip of the catheter beyond a distal tip of the endoscope is controlled.

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23-11-2017 дата публикации

System and method for temperature enhanced irreversible electroporation

Номер: US20170333109A1
Автор: James A. Gilbert
Принадлежит: COVIDIEN LP

An electrosurgical generator is disclosed. The electrosurgical generator includes: a power supply configured to output DC power; an inverter coupled to the power supply, the inverter including a plurality of switching elements; and a controller coupled to the inverter and configured to signal the inverter to simultaneously generate based on the DC power a radio frequency heating waveform and an electroporation waveform.

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07-12-2017 дата публикации

NERVE SPARING TREATMENT SYSTEMS AND METHODS

Номер: US20170348052A1
Принадлежит:

Treatment systems are provided, which comprise a treatment element applying a treatment to a tissue, a stimulation element optically stimulating nerves in the tissue, a sensing unit sensing an electrical signal produced by nerves in the tissue in response to the optical stimulation, and a control unit controlling the application of the treatment according to the sensed signal. The systems and methods are used to avoid damaging nerves by sensing them during operation and immediately before local treatment application and preventing energy emission when the treatment tool is too close to specified nerves. Additional electric stimulation may be provided to enable avoidance of nerve damages on a larger scale, the treatment may be applied by a cold laser, and the control unit may control the treatment in realtime and in a closed loop and immediate prevent further treatment upon sensing optically stimulated nerves. 129.-. (canceled)30. A treatment probe comprising: a treatment element arranged to apply a treatment to a tissue from a tip of the probe,', 'an optical stimulation element arranged to send a stimulation optical signal from the tip of the probe;', 'at least one non-contact electric sensing antenna positioned at the tip of the probe arranged to remotely sense an electrical signal produced by nerves in the tissue, in response to the optical stimulation signal, wherein the non-contact electric sensing antenna is not in direct contact with the tissue; and', 'a control unit arranged to control the application of the treatment in real-time and in a closed loop according to the sensed electrical signal produced by nerves., 'a single probe accommodating31. The treatment probe of claim 30 , wherein the treatment element comprises one of: an optical fiber for laser ablative claim 30 , a radiofrequency electromagnetic radiation (RF) cutting device and microwave radiation cutting device.32. The treatment probe of claim 30 , wherein the optical stimulation element comprises ...

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