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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 9173. Отображено 100.
22-03-2012 дата публикации

Lancet integrated test element tape dispenser

Номер: US20120067006A1
Автор: Daniel Wong, Frank A. Chan
Принадлежит: Roche Diagnostics Operations Inc

A lancet integrated test element tape includes a plurality of lancet integrated test elements. The lancet integrated test elements each include a lancet configured to form an incision in tissue and a test element configured to analyze body fluid from the incision in the tissue. A cartridge includes a supply compartment configured to store an unused section of the tape. The tape is folded within the supply compartment to limit damage to the lancet integrated test elements. The cartridge can further include a waste compartment in which a used section of the tape is stored. An indexing mechanism moves the tape between the supply and waste compartments.

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Номер записи: 1
26-04-2012 дата публикации

Molecular exchange device

Номер: US20120097600A1
Автор: Mark Thomas O'connell, Rodney Ruston, Stewart Jeffrey Block
Принадлежит: Probe Scientific Ltd

The present relates to a molecular exchange device. In particular, the molecular exchange device comprises at least one fluid passageway; and an actuator, the actuator positioned to provide a secondary fluid passageway within at least one of the fluid passageways.

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Номер записи: 2
14-06-2012 дата публикации

Blood collection devices containing blood stabilization agent

Номер: US20120149004A1
Автор: Craig A. Gelfand, Daniel Marchiarullo, Keith Moskowitz
Принадлежит: Becton Dickinson and Co

Disclosed are devices for collecting and stabilizing blood that contain a blood stabilization agent which includes variegin or an analog thereof, a polysulfated disaccharide, or a combination thereof, each in an amount effective to stabilize blood. Methods of making and using the devices, and kits containing the devices, are also provided.

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Номер записи: 3
14-06-2012 дата публикации

Transdermal Sampling and Analysis Device

Номер: US20120150004A1
Автор: John F. Currie, Joseph A. Marcanio, Joseph J. Vidalis, Sundar B. Nadarajan
Принадлежит: Flexible Medical Systems LLC

Transdermal sampling and analysis device, method and system are provided for non-invasively and transdermally obtaining biological samples from a subject and determining levels of analytes of the obtained biological samples. The transdermal sampling and analysis device, method and system may cause disruption to the skin cells to create capillary-like channels from which biological samples may flow to the transdermal sampling and analysis device. The transdermal sampling and analysis device, method and system may collect the biological samples in a reservoir where the biological sample may chemically react with a biologically reactive element. A sensor may convert the produced electrons (ions) into measured electrical signals. The converted signals may be measured and the levels of an analyte may be determined based on the measured signals.

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Номер записи: 4
14-06-2012 дата публикации

Adhesive and peripheral systems and methods for medical devices

Номер: US20120150115A1
Автор: Dean Kamen, Larry B. Gray, Russell H. Beavis
Принадлежит: Deka Products LP

Fill stations and base stations are provided for personal pump systems. The fill stations may be opened and closed to accept a reservoir and to allow fluid to be introduced into the reservoir for use with personal pump systems. The fill stations may hold the reservoir at a tilt relative to an underlying surface and may discourage overfilling of the reservoir. The filling stations may also include viewing windows having fluid lines marked thereon for indicating volume of fluid within the reservoir.

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Номер записи: 5
05-07-2012 дата публикации

Blood collection device

Номер: US20120172754A1
Автор: Rishi Baid
Принадлежит: Poly Medicure Ltd

The application relates to a blood collection device comprising: a cannula hub ( 10 ) defining a chamber ( 28 ); an inlet cannula ( 12 ) defining an axis and having a distal end and a lumen extending therethrough, the inlet cannula being mounted to the cannula hub such that the distal end of the inlet cannula is external of the cannula hub and such that the lumen through the inlet cannula communicates with the chamber; an outlet cannula ( 14 ) having a proximal end and a lumen extending therethrough, the outlet cannula being mounted to the cannula hub such that the proximal end of the outlet cannula is external of the cannula hub and such that the lumen of the outlet cannula communicates with the chamber; a closed sleeve ( 34 ) mounted over a portion of the outlet cannula disposed externally of the cannula hub; and a venting mechanism ( 38 ) providing communication between the chamber and ambient surroundings.

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Номер записи: 6
12-07-2012 дата публикации

Injection device with puncture function, method for controlling injection device with puncture function, chemical solution administration device, and method for controlling chemical solution administration device

Номер: US20120179016A1
Автор: Toshiaki Iio, Yoshinori Amano
Принадлежит: Individual

An injection device with a puncture function includes, in a single casing, a cylindrical cartridge in which insulin is enclosed, a cartridge holder to which the cartridge is inserted, a needle inserted at a front end of the cartridge, a reciprocation unit for reciprocating the cartridge toward the needle, and an extrusion member for extruding the insulin from a rear end of the cartridge toward the needle, and the motion speed and the motion amount of the reciprocation unit are made variable.

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Номер записи: 7
16-08-2012 дата публикации

Patch-sized fluid delivery systems and methods

Номер: US20120209179A1
Автор: Dean Kamen, Eric Yeaton, Larry B. Gray
Принадлежит: Deka Products LP

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

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Номер записи: 8
16-08-2012 дата публикации

Adhesive and peripheral systems and methods for medical devices

Номер: US20120209207A1
Автор: Eric Yeaton, Larry B. Gray
Принадлежит: Deka Products LP

A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

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Номер записи: 9
23-08-2012 дата публикации

Integrated spot monitoring device with fluid sensor

Номер: US20120215132A1
Автор: Christopher D. Wiegel, Daniel Wong
Принадлежит: Roche Diagnostics Operations Inc

A bodily fluid sampling device is operable to breach the skin surface and allow bodily fluid to emerge from the breach location. The bodily fluid sampling device further evaluates the amount of bodily fluid emerged from breach location and determines whether the amount is sufficient or insufficient for a particular purpose, such as sampling and testing. The determination is accomplished automatically without moving the device. The user may also intervene to perform a variety of tasks following the determination of the amount of bodily fluid.

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Номер записи: 10
27-09-2012 дата публикации

Glucose Monitoring System

Номер: US20120245445A1
Автор: Anita Margarette Chambers, Michael Darryl Black, Trent Huang
Принадлежит: Individual

A body fluid sampling system for use on a tissue site includes a drive force generator and one or more microneedles operatively coupled to the drive force generator. Each of a microneedle has a height of 500 to 2000 μm and a variable tapering angle of 60 to 90°. A sample chamber is coupled to the one or more microneedles. A body fluid is created when the one or more microneedles pierces a tissue site flows to the sample chamber for glucose detection and analysis.

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Номер записи: 11
25-10-2012 дата публикации

Apparatus for obtaining and analyzing a blood sample with a lancet coupling mechanism

Номер: US20120271126A1
Автор: Hans List, Kai Fluegge
Принадлежит: Roche Diagnostics Operations Inc

An apparatus for obtaining and analyzing a blood sample is presented. The apparatus comprises an integrated drive unit having a common drive source and a drive force transmission gearing that couples a lancet drive, a device for advancing a magazine, and a sample transfer device to the drive source. A tensioning rotor and a drive rotor are mounted so that they are rotatable coaxially to one another. A first cam control converts the rotation of the drive rotor into a radial forward and reverse movement of a drive rod. A second cam control converts the rotational movement of the tensioning rotor into a linear movement of a link slide. A switching link moved by the link slide rotates the magazine an additional step. A third cam control converts the rotational movement of the tensioning rotor into a linear movement of a pressure tappet perpendicular to the piercing axis.

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Номер записи: 12
01-11-2012 дата публикации

Systems and methods for collecting fluid from a subject

Номер: US20120277697A1
Автор: Donald E. Chickering, III, Li Yang Chu, Mark Michelman, Ramin Haghgooie, Shawn Davis
Принадлежит: Seventh Sense Biosystems Inc

Systems and methods for delivering to and/or receiving fluids or other materials, such as blood or interstitial fluid, from subjects, e.g., from the skin. Beading disruptors and/or capillaries may be used for facilitating the transport of fluids from a subject into a device. Beading disruptors may disrupt the “pooling” of bodily fluids such as blood on the surface of the skin and help influence flow in a desired way. A capillary may conduct flow of fluid in the device, e.g., to an inlet of a channel or other flow path that leads to a storage chamber. A vacuum (reduced pressure relative to ambient) may be used to receive fluid into the device, e.g., by using relatively low pressure to draw fluid into the inlet of a channel leading to a storage chamber. The vacuum source may be part of the device.

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Номер записи: 13
08-11-2012 дата публикации

Tissue penetration device

Номер: US20120283539A1
Автор: Dominique M. Freeman, Don Alden, Jeffrey Perry, Mark Castle, Robert Englert, Rodney Kugizaki, Thomas Shoup
Принадлежит: Pelikan Technologies Inc, Sanofi Aventis Deutschland GmbH

A body fluid testing device has at least one penetrating member and a penetrating member driver configured to be coupled to the at least one penetrating member. A plurality of analyte sensors are coupled to a spoked disk substrate. Each of a penetrating member can pass between spokes of the disk substrate to provide that a used penetrating member can be removed and a new penetrating inserted without removing the disk. A disposable houses the at least one penetrating member and the plurality of analyte sensors.

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Номер записи: 14
22-11-2012 дата публикации

Manufacturing electrochemical sensor module

Номер: US20120291254A1
Автор: James L. Say
Принадлежит: Individual

Certain processes for manufacturing an electrochemical sensor module include assembly first and second housing portions of sensor modules; dispensing a sensor fiber across multiple first housing portions; joining the first and second housing portions; and separating the sensor modules by cutting the sensor fiber.

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Номер записи: 15
13-12-2012 дата публикации

Safety Syringe Having A Manually Activated Retractable Needle

Номер: US20120316466A1
Автор: Jamieson W. Crawford, Robert G. Ellis
Принадлежит: Becton Dickinson and Co

A retractable needle assembly includes a housing having a sidewall defining a hollow bore, and an elongate plunger, the distal end of the plunger forming a reservoir within the hollow bore for containing a fluid therein. The plunger is adapted for slideable movement within the hollow bore. The assembly includes a hub disposed within the hollow bore and at least partially supporting a cannula therewith, and a needle retraction member engaged with the hub for manually selectable advancement with respect to a portion of the housing. The needle retraction member may be advanced from an initial position in which at least a portion of the needle is disposed outside the housing, to a retracted position in which the needle is fully surrounded by the housing. The elongate plunger may be advanced about the hub for extracting the fluid into the reservoir or expelling the fluid from the reservoir.

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Номер записи: 16
17-01-2013 дата публикации

Method for the Production of Bodies in Plastic Material Comprising at Least Two Portions Hinged to Each Other by a Single Rotation Pin

Номер: US20130015605A1
Автор: Roberto Sgaravatto, Ulisse Chiarin
Принадлежит: Meus Srl

The present invention relates to a method for the production of bodies in plastic comprising two portions hinged to each other by a single rotation pin. The method comprises the steps: a) predisposing a mould with two distinct forming chambers for the two portions; the mould comprises a third chamber for the single pin, made and positioned in such a way that the pin is formed already aligned along the hinge axis; the mould is provided with a pair of pegs axially distanced from each other to form the third chamber and sliding along the axis between a first and a second operating position; b) positioning the pegs in the first position; c) injecting plastic material inside the chambers; d) shifting the pegs from the first to the second position, bringing the pin to engage inside the seats; e) opening the mould and extracting the two assembled portions.

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Номер записи: 17
14-02-2013 дата публикации

Arrangement for detection of hemolysis

Номер: US20130040333A1
Автор: Mathias Karlsson
Принадлежит: Hemcheck Sweden Ab

The present invention relates to a device for visual detection of hemolysis in a whole blood sample, comprising at least one visible detection compartment and a transfer passage connected to said visible detection compartment, said transfer passage being arranged to permit transfer of a volume of plasma from said sample to said detection compartment and wherein said transfer passage further is arranged with a separation device ( 4 ) for separating plasma from blood cells within said whole blood sample before said plasma reaches the detection compartment, wherein said device is arranged with subpressure means providing a subpressure inside said detection compartment for generating a force urging said volume of plasma to be transferred from said whole blood sample to said detection compartment through said transfer passage and via said separation device.

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Номер записи: 18
14-03-2013 дата публикации

Vessel for blood sampling

Номер: US20130066234A1
Автор: Elke Helftenbein
Принадлежит: PreAnalytiX GmbH

The present invention relates to a vessel for withdrawing blood, the vessel containing a solution which comprises a guanidinium salt, a buffer substance, a reducing agent, and/or a detergent as components. The vessel is particularly suited for withdrawing blood which is to be analyzed with respect to nucleic acids.

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Номер записи: 19
28-03-2013 дата публикации

SYSTEMS AND METHODS FOR PARENTERALLY PROCURING BODILY-FLUID SAMPLES WITH REDUCED CONTAMINATION

Номер: US20130079604A1
Автор: Patton Richard G.
Принадлежит: MAGNOLIA MEDICAL TECHNOLOGIES, INC.

The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media. 120.-. (canceled)21. A method of obtaining a bodily fluid sample from a patient , the method comprising:inserting a first needle into the patient;inserting into a pre-sample reservoir a second needle fluidically coupleable to the first needle;receiving a first volume of bodily fluid into the pre-sample reservoir;after the first volume of bodily fluid has been received into the pre-sample reservoir, removing the second needle from the pre-sample reservoir;inserting the second needle into a first sample vessel; andreceiving a second volume of bodily fluid into the first sample vessel.22. The method of claim 21 , further comprising:after the second volume of bodily fluid has been received into the first sample vessel, removing the second needle from the first sample vessel.23. The method of claim 22 , further comprising:inserting the second needle into a second sample vessel; andreceiving a third volume of bodily fluid into the second sample vessel.24. The method of claim 23 , further comprising:after the third volume of bodily fluid has been received into the second sample vessel, removing the second needle from the second sample vessel.25. The method of claim 24 , further comprising:removing the first needle from the patient.26. The method of claim 21 , wherein the first sample vessel contains a culture medium that is ...

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Номер записи: 20
04-04-2013 дата публикации

System and Method for Monitoring Time Intervals During Blood Parameter Monitoring

Номер: US20130085471A1
Автор: Hans-Otto Maier, Horst Schmoll, Matthias Paetzold, Torsten Doenhoff
Принадлежит: B Braun Melsungen AG

A system and method for monitoring at least one blood parameter of the blood of different patients, comprising a plurality of access devices for establishing at least one means of access to the blood of each patient through the skin, a plurality of removal devices for removing a quantity of blood from each patient in order to obtain at least one blood sample, at least one blood analysis device for analysing the blood sample with respect to predeterminable blood parameters and for generating individual blood parameter data sets, a calculation device which can be used jointly for a plurality of blood parameter data sets of different patients for calculating data sets of drug parameters of the drugs to be administered to the respective patient on the basis of the individual blood parameter data sets, and a plurality of supply devices for supplying the respective drug having the calculated drug parameters.

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Номер записи: 21
02-05-2013 дата публикации

Simultaneous acquisition of biometric data and nucleic acid

Номер: US20130106568A1
Автор: Lori Hennessy, Michael Harrold, Robert Lagace
Принадлежит: Life Technologies Corp

Disclosed are devices and methods for collection and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of a test subject, while keeping the sample and signature associated with each other. Such devices and methods are used in forensic, human identification, screening, and access control technologies to rapidly process an individual's identity or determine the identity of an individual.

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Номер записи: 22
09-05-2013 дата публикации

METHOD AND APPARATUS FOR ACQUIRING BLOOD FOR TESTING

Номер: US20130116597A1
Автор: Guo Yibo, Rahn Peter, Rudge James, Sanchez Carl, Welsh Emmet
Принадлежит: PHENOMENEX, INC.

A blood sampling device is provided having holder with a manipulating end and an absorbent probe on the opposing end. The probe is of hydrophilic polymer sized to directly absorb a predetermined volume of up to about 30 microliters of blood. Ribs on the holder position the probe within a compartment of a container to prevent contact with the container. The ribs also position the probe within extraction wells. 1. A biological fluid sampling device , comprising:{'sup': '2', 'an absorbent probe made of a hydrophilic polymeric material of sufficient size to absorb for analysis a maximum of about 20 μl of blood in about 2-5 seconds without separating the blood from plasma, the probe having a length of less than about 5 mm and a cross-sectional area of less than about 20 mmand a density of less than about 4 g/cc with a majority of the exterior surface of the probe being exposed and available for placing against a fluid sample on a surface to absorb the sample; and'}a holder connected to the probe.2. The device of claim 1 , wherein the holder is dimensionally suited for use with devices that can manipulate a pipette tip.3. The device of claim 1 , wherein the holder is disposable and the probe has a pore volume of about 40%.4. The device of claim 1 , wherein the density is about 0.6 g/cc and the volume is about 25 microliters.5. The device of claim 1 , wherein the probe has a cylindrical portion that is sized to fit into a mating opening in the holder to connect the holder to the probe.6. The device of claim 1 , wherein the probe is made of polyethylene.7. The device of claim 1 , wherein the probe and holder are sterile and packaged in a sterile container.8. The device of claim 1 , wherein the probe contains dried anti-coagulant.9. The device of claim 1 , wherein the probe contains at least one of a reference standard claim 1 , a dried stabilizer or a modifier.10. The device of claim 1 , wherein the probe contains dried blood.11. The device of claim 1 , wherein the holder ...

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Номер записи: 23
23-05-2013 дата публикации

Diagnostic system

Номер: US20130131479A1
Автор: Alison Ruth Norcott, Christopher David Dunn, Eric Siu, Ernesto Monis Hueso, Ian Frederick Johnson, John Michael Kelly, Richard Sokolov
Принадлежит: Individual

A composite diagnostic system comprising a support member having a membrane penetration element; a bodily fluid collection point positioned for collection of a bodily fluid released by application of the membrane penetration element to a user's body; a test material positioned in the support member such that in use the bodily fluid is brought into contact with the test material.

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Номер записи: 24
23-05-2013 дата публикации

Body fluid testing device

Номер: US20130131480A1
Автор: Hugo Schrem, Volker Zimmer, Werner Ruhl
Принадлежит: Roche Diagnostics Operations Inc

Body fluid testing device for analyzing a body fluid comprises a test media tape adapted to collect the body fluid. The test media tape comprises a tape and test media portions. A free tape portion without test medium is located between successive test media portions. The testing device further comprises a supply portion. The supply portion comprises a housing in which uncontaminated test media tape is contained. The housing further has an opening for withdrawing test media tape from the housing. The testing device further has a sealing means for closing the opening against the surrounding. A free tape portion of the test media tape is located between a wall of the housing and the sealing means when the sealing means closes the opening. Further aspects concern a test media cassette with sealing means and a method for providing test media while holding them sealed against humidity during onboard storage.

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Номер записи: 25
30-05-2013 дата публикации

Delivering and/or receiving fluids

Номер: US20130138058A9
Автор: A. David Boccuti, Christopher J. Morse, Donald E. Chickering, III, Greg Fisher, Javier Gonzalez-Zugasti, Maisam Dadgar, Mark Michelman, Ramin Haghgooie, Richard L. Miller, Scott James, Shawn Davis
Принадлежит: Seventh Sense Biosystems Inc

The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication.

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Номер записи: 26
27-06-2013 дата публикации

Fluid injection and safety system

Номер: US20130160532A1
Автор: Eugene Lim, Gil Rivas, Jeffrey T. Chiou, Michael Butler
Принадлежит: Optiscan Biomedical Corp

Various medical systems and methods are described, including a medical monitoring system. The medical monitoring system can have a fluid system configured to receive bodily fluid and optically analyze said fluid to determine analyte concentration. The fluid system can have a removable portion. The removable portion can have an opening with a port. The system can also have a container configured to contain anticoagulant. The container can have a portion configured to mate with the port of the removable portion. The container can be further configured to not fit into a conventional luer fitting. An anti-coagulant insertion apparatus is also described. The apparatus can have a syringe, a dock with a port, and an adapter configured to connect the syringe to the port. The dock can also have a tab configured to move with the port.

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Номер записи: 27
04-07-2013 дата публикации

Emergency Medical Diagnosis and Communications Device

Номер: US20130172689A1
Автор: Dossas Vasilios D., Dy Lady C., Kraft Clifford H.
Принадлежит:

A portable emergency medical device capable of communicating with a remote location preferably as a cellular telephone that can measure one or more human vital parameters such as pulse rate, body temperature, skin moisture, blood pressure, ECG or blood chemistry and can receive symptoms from a user either by voice recognition or by keypad and can provide an expert medical diagnosis. The device can store a complete medical history for one or more users and can use an expert system to make the diagnosis. The device can make an emergency medical call either on command or automatically requesting help and optionally supplying medical information and/or GPS location information. 1. A personal medical diagnosis apparatus comprising:a cellular telephone module including a processor and memory;a medical expert system disposed in said memory and executable on said processor;a medical probe that measures at least one human medical parameter, said probe being in data communication with said medical expert system; andan input device, including a keyboard and circuitry through which the medical expert system receives symptom data;the expert system receiving imputed symptom data and at least one medical parameter and making a medical diagnosis.2. The personal medical diagnosis apparatus of further comprising a GPS receiver in communication with said processor claim 1 , wherein said processor is adopted to report a geographic location of said medical diagnosis apparatus to a remote station.3. The personal medical diagnosis apparatus of further comprising a housing wherein said medical probe is at least one of:a blood pressure sensor in or deployable from said housing;a pulse rate sensor in or deployable from said housing;a body temperature sensor in or deployable from said housing, or;an ECG interface in or deployable from said housing.4. The personal medical diagnosis apparatus of further comprising a housing wherein said medical probe is at least one of:a blood pressure sensor ...

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Номер записи: 28
04-07-2013 дата публикации

DEVICES AND METHODS FOR BODY FLUID SAMPLING AND ANALYSIS

Номер: US20130172698A1
Автор: Bloom Daniel R., Escutia Raul, Hu Charles, Larkin John F., Reynolds Paul D., Tomasco Michael F., Vivolo Joseph A., Wiard Richard M.
Принадлежит: Intuity Medical, Inc.

Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member. 1. An integrated body fluid sampling meter comprising:a meter housing comprising a light source and a first detector; anda disposable cartridge insertable into the meter housing and comprising a plurality of cells, wherein each cell has a first wall comprising a viewing window and a second wall comprising a light-blocking covering,wherein one of the plurality of cells is positionable between the light source and the first detector.2. The meter of wherein the disposable cartridge is rotatable within the meter housing.3. The meter of wherein the meter is configured to initiate an indexing protocol upon insertion of the disposable cartridge into the meter housing claim 2 , wherein the integrity of each cell is checked.4. The meter of further comprising a processor claim 3 , and wherein the processor is configured to index each cell as either available or used during the indexing protocol.5. The meter of wherein the meter housing comprises a contact pad and wherein the disposable cartridge is movable between a testing position claim 4 , where an available cell is aligned with the contact pad claim 4 , and a standby position claim 4 , where each of the plurality of cells is out of alignment with the contact pad.6. The meter of wherein the light-blocking covering is a foil seal.7. The meter of wherein the meter housing comprises a punch for puncturing the foil seal.8. The meter of wherein the ...

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Номер записи: 29
01-08-2013 дата публикации

BIODETECTOR

Номер: US20130197334A1
Автор: Niestroj Robert, Weber Ekkehardt
Принадлежит: GILUPI GMBH

The invention concerns a Biodetector with a functionalised surface for isolating molecules or cells from the human body. In order to improve a Biodetector of the type mentioned above such that the functionalised surface of the Biodetector or there upon enriched molecules or cells are exposed to a lower abrasion, and the biocompatibility of the Biodetector is improved, the Biodetector is designed to remove a fluid from the human body and absorb it into an inner space of the Biodetector, wherein the functionalised surface is oriented to the inner space of the Biodetector. 1. Biodetector with comprising:a functionalised surface for isolation of molecules or cells from a human body, wherein the Biodetector is configured to remove a fluid from the human body, and to absorb it into an inner space of the Biodetector, wherein the functionalised surface is oriented to the inner space of the Biodetector.2. Biodetector according to claim 1 , wherein the functionalised surface is at least partially occupied with detection molecules.3. Biodetector according to claim 2 , wherein the detection molecule includes antibodies claim 2 , selected from a group consisting of monoclonal antibodies claim 2 , chimeric antibodies claim 2 , humanized antibodies claim 2 , antibody fragments or amino acid structures and amino acid sequences claim 2 , nucleic acid structures and nucleic acid sequences claim 2 , carbohydrate structures claim 2 , and synthetic structures.4. Biodetector according to claim 2 , wherein the detection molecules are of non-human origin.5. Biodetector according to claim 1 , wherein the detection molecules are connected and oriented to the functionalised surface.6. Biodetector according to claim 1 , wherein the detection molecules are covalently attached to the functionalised surface.7. Biodetector according to claim 1 , wherein the Biodetector has a fluid removable section claim 1 , which satisfies at least one of the following requirements:a. The fluid removal section ...

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Номер записи: 30
12-09-2013 дата публикации

Blood Collection Assembly Having a Multi-Function Shield

Номер: US20130237927A1
Автор: Lee Hoong Sim, Tiong Yee Sim
Принадлежит: Becton Dickinson and Co

A needle assembly includes a housing having proximal and distal ends, an IV cannula projecting distally from the housing, and an IV shield having an engagement. The housing has a shield seat and the IV cannula has a distal tip. The IV shield has a pre-use position where the IV shield covers the distal tip of the IV cannula and the engagement is disengaged from the shield seat, and a use position where the engagement is engaged with the shield seat and the IV shield is adapted to move between a non-shielded position, in which the distal tip is exposed, and a shielded position, in which the distal tip is shielded by the IV shield.

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Номер записи: 31
03-10-2013 дата публикации

Sensing Patch Applications

Номер: US20130261409A1
Автор: Edwards David N., Pathak Srikant
Принадлежит:

Various methods, devices and systems for patch based physical, physiological, chemical, and biochemical sensors that diagnose and monitor disease states are described. The patch based sensors provide a panel of specific analyte parameters that determine one or more physiological conditions and/or the level of healing progression of a wound. The use of such analyte panels in local or remote monitoring of parameters related to various disease states is also described. 1. A wound healing indicator device comprising:a functional layer, wherein the functional layer determines the level of at least one specific parameter from wound exudates and provides an indication as to the status of a wound healing process.2. The wound healing indicator device of claim 1 , further comprising a carrier layer.3. The wound healing indicator device of claim 1 , further comprising a sampling layer.4. The wound healing indicator device of claim 3 , wherein the sampling layer operates through at least one of an electrophoretic mechanism claim 3 , an electrokinetic mechanism claim 3 , a capillary effect claim 3 , a pressure driven mechanism claim 3 , and combinations thereof.5. The wound healing indicator device of claim 1 , wherein the at least one specific parameter includes concentration of chemical or biochemical agents associated with at least one of bacteria claim 1 , inflammation cytokines claim 1 , proteases claim 1 , growth factors claim 1 , ECM receptors claim 1 , pH claim 1 , iconicity claim 1 , NO/O claim 1 , temperature claim 1 , integrins claim 1 , and combinations thereof.6. The wound healing indicator device of claim 1 , wherein the status of the wound healing process is indicated through at least one of a color change claim 1 , a digital display claim 1 , and combinations thereof.7. The wound healing indicator device of claim 6 , wherein the color change is provided by use of at least one of a coulometric assay claim 6 , a luminescence assay claim 6 , an electrochemical assay ...

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Номер записи: 32
10-10-2013 дата публикации

Eliciting a Blood Sample

Номер: US20130267807A1
Автор: Macarthur Ross, Richter Frank
Принадлежит: SANOFI-AVENTIS DEUTSCHLAND GMBH

Apparatus for eliciting a blood sample comprises: a housing; a shaft mounted within the housing; an aperture in the housing, the aperture being configured to receive a part of a user; a member rotatably mounted on the shaft; a lancet protruding from one position at an edge of the member, and a blood collection part located at a second, different position at the edge of the member. The apparatus is configured such that: when the member is in a first rotational position the lancet is shielded by the housing, when the member is in a second rotational position the lancet is operable to lance the part of the user received at the aperture, and when the member is in a third rotational position the blood collection part is presented such as to receive blood from the part of the user received at the aperture. 1. Apparatus for eliciting a blood sample , the apparatus comprising:a housing;a shaft mounted within the housing;an aperture in the housing, the aperture being configured to receive a part of a user;a member rotatably mounted on the shaft;a lancet protruding from one position at an edge of the member,a blood collection part located at a second, different position at the edge of the member,wherein the apparatus is configured such that:when the member is in a first rotational position the lancet is shielded by the housing,when the member is in a second rotational position the lancet is operable to lance the part of the user received at the aperture, andwhen the member is in a third rotational position the blood collection part is presented such as to receive blood from the part of the user received at the aperture.2. Apparatus according to claim 1 , wherein the member further comprises at least two electrical contact points connected to the blood collection part for communication with a meter for determining a parameter of blood chemistry.3. Apparatus as claimed in claim 1 , wherein the blood collection part includes a wicking or absorbent part and an analyte measurement ...

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Номер записи: 33
17-10-2013 дата публикации

FULLY INTEGRATED WEARABLE OR HANDHELD MONITOR

Номер: US20130274568A1
Автор: Emery Jeffrey L., Escutia Raul, Litherland Craig M., Pamichev Christo P., PFEIFFER James W.
Принадлежит:

An arrangement comprises a housing containing one or more components configured for at least one of body fluid sampling and analysis. The arrangement includes a housing containing one or more components configured for at least one of body fluid sampling and analysis, and a body attachment element. The housing and the body attachment element are connected by a quick-release mechanism configured to facilitate removal of the housing from the body attachment element. 1. An integrated body fluid sampling and analysis device , the device comprising:a housing, the housing containing a plurality of body fluid sampling and analysis sites, each of the sites comprising a skin-penetration member;a body attachment element; anda quick release mechanism connecting the housing and the body attachment element.2. The arrangement of claim 1 , wherein the body attachment element comprises a band configured to be secured to the wrist of a wearer.3. The arrangement of claim 1 , further comprising a disposable portion and a reusable portion.4. The arrangement of claim 1 , wherein each of the sampling and analysis sites further comprises an actuator configured to drive the skin-penetration member into the skin of a user.5. The arrangement of claim 4 , wherein the actuator is configured to accelerate the skin-penetration member along a curved or rotational path.6. The arrangement of claim 5 , wherein the actuator comprises a torsional spring.7. The arrangement of claim 4 , wherein each of the sampling and analysis sites further comprise a trigger configured to release the actuator.8. The arrangement of claim 1 , wherein the skin-penetration member comprises a hollow needle.9. The arrangement of claim 1 , wherein the analyte quantification member comprises an assay pad claim 1 , the assay pad comprising a chemical reagent for producing a detectable signal upon reaction with a target analyte.10. The arrangement of claim 9 , wherein the signal is optically detectable claim 9 , and the ...

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Номер записи: 34
17-10-2013 дата публикации

Allowing measurements to be made of a blood sample

Номер: US20130274579A1
Автор: Frank Richter, Ross Macarthur
Принадлежит: Sanofi Aventis Deutschland GmbH

An apparatus and a method for measuring a property of a blood sample is shown. The apparatus comprises of a housing having an aperture; a shaft mounted inside the housing; a testing member rotatably mounted on the shaft; an actuating member coupled to the housing and configured to exert a force against the testing member; and a lancet for eliciting a blood sample fixedly coupled to and protruding substantially radially from the testing member and configured to co-rotate with the testing member. The apparatus is further configured such that the lancet is aligned with the aperture in the housing when the testing member is in a first position. The testing member is configured, in the presence of a force exerted against the testing member by the actuator member, to translate to a second position in which the lancet is in a skin penetrating position.

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Номер записи: 35
17-10-2013 дата публикации

BLOOD SAMPLE COLLECTION

Номер: US20130274631A1
Автор: Macarthur Ross, Richter Frank
Принадлежит: SANOFI-AVENTIS DEUTSCHLAND GMBH

Apparatus comprises: a housing, the housing having an aperture; a shaft; and plural blood sample collection members supported on the shaft. The apparatus is constructed such that different ones of the plural blood sample collection members are able to be presented at the aperture in turn. Each of the blood sample collection members may be independently rotatable about the shaft. 115-. (canceled)16. Apparatus comprising:a housing, the housing having an aperture;a shaft; andplural blood sample collection members supported on the shaft, wherein each of the blood sample collection members is independently rotatable about the shaft andwherein the apparatus is constructed such that different ones of the plural blood sample collection members are able to be presented at the aperture in turn.17. Apparatus as claimed in claim 16 , wherein the shaft is rotatable in the housing claim 16 , and wherein the shaft includes a drive dog that is operable to mate with a corresponding feature in the blood sample collection member claim 16 , so as to allow the blood sample collection members to be controllably rotated within the housing.18. Apparatus as claimed in claim 16 , wherein the location of the aperture in the housing is fixed and wherein the plural blood sample collection members are moveable along the housing.19. Apparatus as claimed in claim 18 , wherein each of the blood sample collection members includes at least one guide slot and wherein the housing is provided with at least a first guide on an internal surface thereof claim 18 , the first guide being configured so as to allow rotation of one of the blood sample collection members with the shaft and so as to restrict rotation of blood sample collection members other than the one of the blood sample collection members.20. Apparatus as claimed in claim 19 , wherein the first guide extends along part of the internal surface of the housing in a direction approximating an axis of the shaft and is absent from a location that ...

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Номер записи: 36
28-11-2013 дата публикации

Analyte testing method and system with high and low analyte trends notification

Номер: US20130318439A1
Автор: Anita Mathew, Jeremy Landis, Salve Retuta Pascual
Принадлежит: Life Scan Inc

Described herein are systems and methods to utilize factual information based on stored analyte data to allow greater insight into the management of diabetes of a user.

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Номер записи: 37
02-01-2014 дата публикации

Providing an id-verified blood test

Номер: US20140002235A1
Автор: Aaron K. Baughman, Peter K. Malkin
Принадлежит: International Business Machines Corp

Providing an ID-verified blood test, in one aspect, may include enabling a user to press a finger against a fingerprint-reading panel and reading a fingerprint of the user. A blood sampling device coupled to the fingerprint-reading panel may be activated while the user has the finger against the fingerprint-reading panel to sample blood from the finger. Blood may be sampled from the user via the blood sampling device while the user has the finger against the fingerprint-reading panel. A test may be performed on the sampled blood to determine a level of specified chemical in the blood. User identification may be determined based on the fingerprint. The determined user identification and the level of the specified chemical may be returned.

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Номер записи: 38
16-01-2014 дата публикации

Bodily Fluid Analysis Device

Номер: US20140018652A1
Автор: Schabbach Michael
Принадлежит: SANOFI-AVENTIS DEUTSCHLAND GMBH

An apparatus comprising a substrate, the substrate having supported thereon: 113-. (canceled)14. An apparatus comprising a substrate , the substrate having supported thereon:plural collectors each for collecting a bodily fluid from the surface of a body part placed adjacent thereto;at least two pairs of electrodes integral with each of the collectors;an analyser for analysing each collected bodily fluid, wherein the analyser comprises a controller, wherein each of the at least two pairs of electrodes are connected to the analyser and wherein the analyser is configured to analyse at least one electrical signal received via a first pair of the at least two pairs of electrodes; anda display for displaying an indication of a result of each analysis, wherein the apparatus is configured to activate the analyser in response to a predetermined electrical signal received via a second pair of the at least two pairs of electrodes.15. An apparatus according to claim 14 , wherein a bodily fluid collecting end of each of the collectors is covered by a removable seal.16. An apparatus according to claim 15 , wherein each removable seal provides a fluid impermeable barrier around the bodily fluid collecting end of the respective collector.17. An apparatus according to claim 14 , wherein the apparatus is configured to activate the display in response to a predetermined electrical signal received via the second pair of electrodes.18. An apparatus according to claim 14 , wherein the apparatus is configured to activate the display in response to a predetermined electrical signal received via a third pair of the at least two pairs of electrodes integral with each collector.19. An apparatus according to claim 14 , wherein each second pair of electrodes is located further from a bodily fluid collecting end of the respective collector than each first pair of electrodes.20. An apparatus according to claim 18 , wherein each third pair of electrodes is located closer to a bodily fluid ...

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Номер записи: 39
23-01-2014 дата публикации

Enhanced Laser Vein Contrast Enhancer with Projection of Analyzed Vein Data

Номер: US20140024952A1
Автор: Conlon Stephen, Goldman Ron, Luciano Vincent, Wood Fred
Принадлежит:

It is known in the art to use an apparatus to enhance the visual appearance of the veins and arteries in a patient to facilitate insertion of needles into those veins and arteries. This application discloses a number of inventions that add additional data collection and presentation capabilities to a handheld vein enhancement apparatus and a set of processes for the collection of blood and the delivery of IV medicines that use the handheld device to mediate the process. 1. A handheld system for assisting in the performance of a venipuncture procedure , said system comprising:a display means;a microprocessor, said microprocessor coupled to a memory, and thereby configured to access patient data stored therein and associated with a respective bar code, said patient data comprising patient identification data and required venipuncture data;a first laser configured to emit a beam of light at a first wavelength;a second laser configured to emit a beam of light at a second wavelength;an image capture means responsive to said first and second wavelengths of light;means for scanning, said means for scanning configured to scan said first wavelength of light, with said image capture means and said microprocessor thereby configured to decode a bar coded patient wrist band, and to provide said required venipuncture data corresponding to said bar code, upon said display means;said means for scanning further configured to scan said second wavelength of light in a pattern onto a target area of the patient to form a contrasted image of subcutaneous veins of the target area by differential absorption between the subcutaneous veins and the surrounding tissue therein, said image capture means further configured to output a signal representing said contrasted image to said second laser, with said means for scanning configured to receive said contrasted image from said second laser and to thereby scan said imaged subcutaneous veins in said contrasted image onto the target area using ...

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Номер записи: 40
23-01-2014 дата публикации

Patch-sized fluid delivery systems and methods

Номер: US20140025001A1
Автор: Dean Kamen, Larry Brian Gray, Russell H. Beavis
Принадлежит: Deka Products LP

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

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Номер записи: 41
13-02-2014 дата публикации

DEVICE FOR ASSISTING WITH THE SAMPLING OF A BIOLOGICAL FLUID PRESENT IN A CAVITY

Номер: US20140046213A1
Автор: Benbunan Marc
Принадлежит: ASSISTANCE PUBLIQUE HOPITAUX DE PARIS

A device for assisting with the sampling of a biological fluid present in a cavity, which device can co-operate with a puncture needle, the device including a holding member for keeping the device and the needle rigidly connected to one another while the needle is being inserted into the cavity; and a securing device which, following the introduction of the needle into the cavity, can be secured to an internal wall of the cavity. 1. Device for assisting with the sampling of a biological fluid present in a cavity , said device can constructed and arranged to cooperate with a puncture needle , said device comprising:a holding member for keeping the device and the needle rigidly connected to one another, while the needle is being inserted into the cavity;a securing device which, following the introduction of the needle into the cavity, can be secured to an internal wall of the cavity.2. Device according to claim 1 , wherein the securing device includes a plurality of fins secured on the holding member.3. Device according to wherein the holding member is a ring able to surround at least one portion of the needle while hugging the external shape of the needle.4. Device according to claim 1 , wherein the holding member and the securing device are made from metal.5. Device according to claim 1 , wherein the holding member and the securing device are made of plastic.6. Device according to claim 1 , comprises comprising a maintaining device claim 1 , and wherein the securing device is able to take two positions:a retracted position according to which the securing device is maintained retracted by the maintaining device, such that the securing device is able to be maintained against the internal wall of the needle.a deployed position according to which the securing device opens out from the holding member during the removal of the maintaining device, such that the securing device is able to come into contact with the internal wall of the cavity.7. Device according to claim 6 ...

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Номер записи: 42
27-02-2014 дата публикации

Fluid handling cassette

Номер: US20140058228A1
Автор: James R. Braig, Jennifer H. Gable, Kenneth I. Li, Mark Wechsler, PENG Zheng, Richard Keenan
Принадлежит: Optiscan Biomedical Corp

A fluid handling module that is removably engageable with a bodily fluid analyzer is provided. The module may comprise a fluid handling element, and a fluid component separator that is accessible via the fluid handling element and configured to separate at least one component of a bodily fluid transported to the fluid component separator. The fluid handling element may have at least one control element interface.

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Номер записи: 43
06-03-2014 дата публикации

Biological Sample Collection Device and System

Номер: US20140066726A1
Автор: COSTELLO BENEDICT
Принадлежит: PROTEUS DIGITAL HEALTH, INC.

A biological sample collection device includes a top cover plate, a bottom portion attached to the top cover plate, the bottom portion comprising a remotely-analyzable biological sample collection portion to collect a biological sample from a body of a subject. The biological sample is to be analyzed at a remote processing facility at a later time. A fastening portion is provided on the bottom portion to affix the remotely-analyzable biological sample collection device to the body of the subject. A real time clock is coupled to the top cover plate and a memory is coupled to the top cover plate and electrically coupled to the real time clock. The remotely-analyzable biological sample collection device may further include a processing unit, at least two electrodes coupled to the processing unit, and a transbody conductive communication module. Additionally, a remotely-analyzable biological sample collection device communication system includes a wireless communication device configured to communicate with a communication device external to the patient. 1. A biological sample collection device , comprising:a top cover plate;a bottom portion attached to the top cover plate, the bottom portion comprising a remotely-analyzable biological sample collection portion to collect a biological sample from a body of a subject, wherein the biological sample is to be analyzed at a remote processing facility at a later time;a fastening portion provided on the bottom portion to affix the remotely-analyzable biological sample collection device to the body of the subject;2. The biological sample collection device of claim 1 , comprising a real time clock coupled to the top cover plate.3. The biological sample collection device of claim 2 , comprising a memory coupled to the top cover plate and electrically coupled to the real time clock.4. The biological sample collection device of claim 3 , wherein the memory coupled to the real time clock is operative to time-stamp when the ...

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Номер записи: 44
06-03-2014 дата публикации

Apparatus and Method for Measuring Biochemical Parameters

Номер: US20140066734A1
Автор: Zdeblick Mark
Принадлежит: PROTEUS DIGITAL HEALTH, INC.

In a first embodiment, electrodes are coupled to a surface at first, second, and third locations, the first location being further from the third location than from the second location. Impedance is measured at distinct frequencies between pairs of the electrodes. As a result, impedance is measured at differing regions below the surface, one region being deeper below the surface than the other region. In a second embodiment, a microfluidic device carries out an analysis. The analysis may be within a flexible patch adhered to a surface, or may be in a solid device implanted in a body of liquid surrounded by tissue. The analysis may involve pumping a fluid or may involve drawing an analyte electrophoretically through a microfluidic channel. 1. (canceled)2. Apparatus comprising:an adhesive patch disposed for adhesion to a surface;the patch being flexible;the patch comprising a microfluidic channel disposed to receive fluid from the surface;the patch further comprising a pump connected with the channel, the pump responsive to a control signal for pumping fluid received from the surface along the microfluidic channel;the patch further comprising a sensor positioned along the channel, the sensor disposed to sense a biochemical parameter of interest and responsive to the sensing to generate a data signal;the patch unpowered by any power source external thereto and further comprising an electrochemical cell;the patch wirelessly communicatively coupled to electronic equipment external thereto by means of a wireless communications link;the patch further comprising a microcontroller controlling the pump by means of the control signal, the microcontroller receiving the data signal from the sensor, the microcontroller connected to the electrochemical cell to be powered thereby, the microcontroller electrically connected to the wireless communications link;the patch being sterile;the patch contained within a wrapper preserving said sterile condition;wherein the channel diameter ...

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Номер записи: 45
13-03-2014 дата публикации

Portable medical diagnostic systems and methods using a mobile device

Номер: US20140072189A1
Автор: Michal DEPA, Sidhant JENA
Принадлежит: Michal DEPA, Sidhant JENA

A system and method for analysis of colorimetric test strip strips and disease management. The system can include an accessory that is operably coupled to a mobile device, the mobile device acquiring and/or analyzing images of the colorimetric test strips. The light box accessory can be detachably attached to the mobile device, or made to remain attached to the mobile device, but with the capability of having the light box accessory removed from the field of view of the camera for general photography purposes. In other embodiments, an image containing known calibration color(s) and reagent area(s) is obtained sans the light box for comparison with a previous calibration image to model changes in ambient lighting conditions and determine a color correction function. The correction can be applied to the detected reagent area color(s) for matching between the detected reagent area color(s) and reference color(s) on the reference chart. Optionally, the information can be processed and displayed to provide feedback, as well as transmitted to a health provider for analysis.

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Номер записи: 46
13-03-2014 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE COLLECTION

Номер: US20140073990A1
Автор: Burd Tammy, Chen Michael, Holmes Elizabeth A., Ko Pey-Jiun, Lath Adrit, McHale Patricia
Принадлежит: Theranos, Inc.

Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container. 155-. (canceled)56. A device for collecting a fluid sample from a subject , comprising:(a) a body containing at least a portion of at least one collection channel, the collection channel comprising a first opening and a second opening, and being configured to draw a bodily fluid via capillary action from the first opening towards the second opening;(b) at least one adaptor channel having a first opening and a second opening, the first opening aligned with the second opening of the collection channel, and the adaptor channel being configured to penetrate a cap of the sample container; and(c) at least one sample container movable between a first position on the device and a second position on the device to engage the adaptor channel.57. The device of wherein the body comprises at least two collection channels.58. The device of wherein an interior of the collection channel is coated with an anticoagulant.59. The device of claim 57 , wherein an interior of a first of the collection channels is coated with a first anticoagulant different from a second anticoagulant coating an interior of a second of the collection channels.60. The device of claim 59 , wherein the first anticoagulant is ethylenediaminetetraacetic acid (EDTA) and the ...

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Номер записи: 47
13-03-2014 дата публикации

Apparatus and method for manually powered bodily fluid extraction

Номер: US20140073992A1
Автор: Hoi-Cheong S. Sun, Kevin A. Hufford
Принадлежит: Charles Stark Draper Laboratory Inc

Apparatuses and methods are disclosed herein for extracting bodily fluids. The apparatus consists of a housing, a releasable lancet stored in the housing, an inlet flow channel formed in the housing, a mechanically powered vacuum generator, and a storage area formed in the housing. The releasable lancet is released to pierce the skin of the subject to allow fluid to be extracted from the subject. The vacuum generator generates a partial vacuum within the inlet flow channel. After the lancet has pierced the skin of the subject, the partial vacuum draws fluid from the subject and into the inlet flow channel. The storage area is in fluid connection with the inlet flow channel, and receives the fluid drawn from the subject from the inlet flow channel.

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Номер записи: 48
03-01-2019 дата публикации

Safety Blood Collection Assembly With Indicator

Номер: US20190000366A1
Автор: Bartfeld Benjamin R., Chia Neville Yu Leng, Crawford Jamieson W., Ellis Robert G., Moh Jon, Newby C. Mark, Sim Tiong Yee, Tan Chee Leong Alvin, Wilkinson Bradley M.
Принадлежит:

A needle assembly is disclosed. The needle assembly includes a housing having a flash chamber, and having a distal end and a proximal end engageable with a specimen collection container. The assembly includes a cannula having a patient end, a non-patient end, and a sidewall extending therebetween defining a cannula interior. The patient end of the cannula projects at least partially from the distal end of the housing, and the cannula interior is in fluid communication with the flash chamber. The assembly further includes a shield restrainably engaged with a portion of the housing and axially transitionable over the patient cannula from a retracted position in which the patient end is exposed, to an extended position in which the patient end is shielded by at least a portion of the shield, wherein at least a portion of the flash chamber is visible in the retracted position. 1. A needle assembly , comprising:a housing, comprising a front hub portion and a rear hub portion with a flash chamber defined therebetween, the housing having a distal end, and a proximal end engageable with a specimen collection container;a cannula having a patient end, a non-patient end, and a sidewall extending therebetween defining a cannula interior, the patient end of the cannula projecting at least partially from the distal end of the housing, the cannula interior in fluid communication with the flash chamber; anda shield engaged with a portion of the housing and comprising a locking structure, the shield transitionable from a first position to a second position with respect to the housing, wherein the flash chamber includes a top surface which is free from obstructions on the flash chamber and is visible when the shield is in the first position, and wherein the shield is disposed over the patient end of the cannula and the locking structure engages at least one ledge located on the front hub portion when the shield is in the second position.2. The needle assembly of claim 1 , wherein the ...

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Номер записи: 49
03-01-2019 дата публикации

Procoagulant factors suitable for subsequent autologous use

Номер: US20190000367A1
Автор: Niels Erik Holm, Rasmus Lundquist
Принадлежит: Reapplix AS

Provided is a blood collection unit suitable for accelerated blood coagulation of whole blood for subsequent autologous or allogeneic use. The blood collection unit includes an inside surface that an activation site accelerating coagulation by having a high roughness. Further provided is a blood collection unit including an inside surface that has an activation site having a high roughness area, and an interior of the blood collection unit has been prepared with a pressure of no more than 255 mBar, and preferably a pressure of no more than 130 mBar.

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Номер записи: 50
07-01-2016 дата публикации

Venous access device

Номер: US20160000363A1
Автор: Christopher M. Richardson, David L. Nichols, David R. DePoyster, Kelli L. Shada, Spencer A. Jones
Принадлежит: Bvad Technologies LLC

A venous access device includes a hub and a bifurcated cannula. The hub includes a bifurcated connecting arm, a blood sampling arm connected to the bifurcated connecting arm, a fluid transfer arm connected to the bifurcated connecting arm, a blood sampling channel and a fluid transfer channel. The blood sampling channel passes through the blood sampling arm and the bifurcated connecting arm. The fluid transfer channel passes through the fluid transfer arm and the bifurcated connecting arm. The bifurcated cannula is coupled to the bifurcated connecting arm and includes a blood sampling lumen having a blood sampling port, a fluid transfer lumen having a fluid transfer port, and a dividing member separating the blood sampling lumen from the fluid transfer lumen. The blood sampling port is 2 mm to 20 mm proximal from the fluid transfer port. The blood sampling channel is fluidly connected to the blood sampling lumen, and the fluid transfer channel is fluidly connected to the fluid transfer lumen.

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Номер записи: 51
07-01-2021 дата публикации

MEDICAL DEVICE INSERTERS AND PROCESSES OF INSERTING AND USING MEDICAL DEVICES

Номер: US20210000399A1
Автор: Curry Samuel M., Donnay Manuel L., Nguyen Tuan, Pace Louis G., Robinson Peter G., Yee Phillip
Принадлежит:

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. 119-. (canceled)20. A glucose monitoring system comprising: the glucose sensor, wherein a distal end of the glucose sensor is configured to be inserted under skin of the subject;', 'a distal surface including an adhesive layer, wherein the distal surface is configured to be positioned on the skin of the subject such that the adhesive layer adheres to the skin of the subject;', 'an interior of the insertion assembly including a first spring in a loaded position, a second spring, a sliding member, and a straight track having a length, wherein the sliding member is configured to move only within the straight track; and', wherein the button is further configured to release the first spring from the loaded position upon being pressed, such that the first spring causes the sliding member to move within the straight track along a second axis different from the first axis, wherein the second axis is defined by the length of the straight track,', 'wherein movement of the sliding member within the straight track causes an actuator to advance in a distal direction along an insertion axis different from the first axis and the second axis, wherein advancement of the actuator causes advancement of a sharp and the glucose sensor in the distal direction along the insertion axis such that the distal end of the glucose sensor is inserted under the skin of the subject,', 'wherein the sliding member is further configured to continue moving within the straight track after the advancement of the sharp and the glucose sensor in the distal direction along the insertion axis,', 'wherein the sliding member is operatively engaged with the actuator throughout the movement of the sliding member within the straight track,', 'wherein, the second spring is configured to expand and retract the sharp in a proximal direction along the insertion axis while the distal ...

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Номер записи: 52
07-01-2021 дата публикации

MEDICAL DEVICE INSERTERS AND PROCESSES OF INSERTING AND USING MEDICAL DEVICES

Номер: US20210000400A1
Автор: Curry Samuel M., Donnay Manuel L., Nguyen Tuan, Pace Louis G., Robinson Peter G., Yee Phillip
Принадлежит:

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. 119-. (canceled)20. A glucose monitoring system comprising: the glucose sensor, wherein a distal end of the glucose sensor is configured to be inserted under skin of the subject;', 'a distal surface including an adhesive layer, wherein the distal surface is configured to be positioned on the skin of the subject such that the adhesive layer adheres to the skin of the subject;', 'an interior of the insertion assembly including a first spring in a loaded position, a second spring, a sliding member, and a straight track having a length, wherein the sliding member is configured to move only within the straight track; and', wherein the button is further configured to release the first spring from the loaded position upon being pressed, such that the first spring causes the sliding member to move within a first section of the straight track along a second axis different from the first axis, wherein the second axis is defined by the length of the straight track,', 'wherein movement of the sliding member within the first section of the straight track causes an actuator to advance in a distal direction along an insertion axis different from the first axis and the second axis, wherein advancement of the actuator causes advancement of a sharp and the glucose sensor in the distal direction along the insertion axis such that the distal end of the glucose sensor is inserted under the skin of the subject,', 'wherein the sliding member is further configured to move within a second section of the straight track, and wherein the movement of the sliding member within the second section of the straight track causes the actuator to move in a proximal direction along the insertion axis,', 'wherein the second spring is configured to expand and retract the sharp in a proximal direction along the insertion axis while the distal end of the glucose sensor ...

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Номер записи: 53
05-01-2017 дата публикации

METHODS AND SYSTEMS FOR BLOOD GLUCOSE MONITORING

Номер: US20170000349A1
Автор: KRIEF Haim, RAPHAEL Erez
Принадлежит:

The present invention provides for an apparatus, including: a lancing device; a cartridge; where the lancing device is configured to house the cartridge; where the cartridge is configured to house a plurality of test strips and a glucose monitoring apparatus; where the glucose monitoring apparatus is configured to determine a glucose test result from at least one test strip of the plurality of test strips. 112-. (canceled)13. A diabetes management system , comprising:at least one server functioning in a communications cloud to provide cloud based diabetes management, the server having software stored on a non-transient computer readable medium;wherein, upon execution of the software, the at least one server is at least configured to receive test data from a plurality of testing apparatuses, wherein each apparatus comprises:a connecting plug configured to mate with an audio jack phone port on a portable electronic device, wherein the connecting plug is configured to receive power for the apparatus from the audio jack phone port, and wherein the connecting plug is configured to receive data from the audio jack phone port, and wherein the connecting is configured to transmit data from the glucose monitoring apparatus to the audio jack phone port; andwherein the apparatus is configured to determine a test result and to deliver a test result to at least one third party user of a connectable device, by use of a graphical user interface caused to be displayed by the software.14. The system of claim 13 , wherein the communications cloud includes one or more cloud services.15. The system of claim 14 , wherein the cloud services are selected from the group including SaaS services claim 14 , social features claim 14 , CRM claim 14 , Email claim 14 , Virtual desktop claim 14 , thin client claim 14 , and terminal emulator.16. The system of claim 13 , wherein the communications cloud includes a Web Frontend.17. The system of claim 16 , wherein the Web Frontend provides PaaS ...

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Номер записи: 54
07-01-2021 дата публикации

PASSIVE SAFETY I.V. BLOOD COLLECTION CATHETER

Номер: US20210000401A1
Автор: Millerd Donald L.
Принадлежит: MMI, LLC

Apparatus and methods for a single, handheld device that provides for both insertion of a catheter and collection of a fluid. Some embodiments further include a needle that assists in the insertion of the catheter into a blood vessel, and which includes a retraction feature that protects the user from an accidental needle stick when the device is ready for disposal. Still further embodiments include a protective cover that prevents a user from accidentally being stuck by a second needle used for the introduction of the patient's blood into a collection device. 149-. (canceled)50. A method for automatically retracting a needle from a catheter , comprising:providing a first hollow needle extending in a distal direction from the lumen of a catheter;providing a flowpath from the first hollow needle to a second hollow needle, the second hollow needle being aligned with a second axis that is laterally displaced from the first axis of the first hollow needle;extending the tip of the second hollow needle through an aperture in a slidable cover;retracting the first hollow needle from the lumen in a proximal direction along the first axis; andautomatically sliding the cover along the second axis during said retracting.51. The method of which further comprises separating the first hollow needle from the catheter before said retracting.52. The method of wherein said automatically sliding the cover is to a position that is proximal of the tip.53. The method of wherein said extending is in a proximal direction.54. The method of which further comprises automatically locking the cover in a position after said automatically sliding.55. The method of wherein the flowpath is flexible.56. The method of wherein said automatically sliding the cover is by pushing the cover with the retracting first hollow needle.57. The method of wherein said automatically sliding the cover is by expanding a coiled spring. This application claims the benefit of priority to U.S. Provisional Patent ...

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Номер записи: 55
06-01-2022 дата публикации

SYSTEMS AND METHODS TO IMPROVE INSTRUMENT GUIDANCE WITHIN AN INTRAVENOUS CATHETER ASSEMBLY

Номер: US20220001161A1
Автор: Bihlmaier Bryan Fred, Burkholz Jonathan Karl, Staley Shaun
Принадлежит:

A catheter assembly and/or an introducer may include one or more features configured to guide a probe and/or a catheter distally through a septum. The catheter assembly may include a catheter adapter and the septum. The catheter adapter may include a distal end, a proximal end, and a lumen extending therebetween. In some embodiments, the septum may be disposed within the lumen. The septum may include a proximal surface that is tapered inwardly in a distal direction such that the proximal surface of the septum is configured to guide the probe and/or the catheter distally through the septum. The catheter assembly may be configured to receive an introducer, which may include an introducer element. A proximal end of the introducer element may include another proximal surface that is tapered inwardly in the distal direction such that the other proximal surface is configured to guide the probe or the catheter distally through the septum. 1. A catheter assembly , comprising:a catheter adapter, comprising a distal end, a proximal end, and lumen extending therebetween; anda septum disposed within the lumen, wherein the septum comprises a proximal surface that is tapered inwardly in a distal direction such that the proximal surface is configured to guide a probe or catheter distally through the septum.2. The catheter assembly of claim 1 , wherein the septum comprises a cavity claim 1 , wherein a distal end of the cavity comprises an annular protrusion claim 1 , wherein annular protrusion forms the proximal surface.3. The catheter assembly of claim 2 , wherein the septum further comprises a slit disposed in a center of the annular protrusion.4. The catheter assembly of claim 1 , further comprising extension tubing claim 1 , wherein the proximal end of the catheter adapter comprises a first port and a second port claim 1 , wherein the lumen comprises a first lumen claim 1 , a second lumen claim 1 , and a common lumen claim 1 , wherein the first port forms the first lumen claim ...

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Номер записи: 56
07-01-2016 дата публикации

Methods and Devices for Collecting Body Fluids

Номер: US20160000613A1
Автор: Miller Denise H.
Принадлежит:

The present invention comprises methods and devices for collection of fluids, including cells and cellular materials, from the uterus. A device of the present invention comprises a central tubing member to which, at least, a flexible tubing member and an absorbable member are connected at least at one point. The absorbable member is connected to at least one portion of the central tubing member and to at least one portion of the flexible tubing member. The devices of the present invention are useful in methods of collection of uterine fluids, including blood, cells and cellular material. 112.-. (canceled)13. A method for collecting stems cells in uterine fluids , comprising , a central tubing member comprising a proximal end and a distal end, wherein the proximal end has at least one opening and the distal end is closed;', 'a flexible tubing member connected to the central tubing member in a region near the proximal end of the central tubing member; and', 'an absorbent member attached along the length of the flexible tubing member,, 'a) providing an intrauterine device in a compressed state to an intrauterine cavity of a mammal, the intrauterine device comprisingwherein the compressed state of the intrauterine device comprises, the flexible tubing member and the absorbent member in close proximity or wrapped around the central tubing memberb) maintaining the intrauterine device within the intrauterine cavity for more than one day to collect and retain uterine fluids within a reservoir portion located inside the central tubing member;c) removing absorbed fluids and cells from the intrauterine device; andd) separating the stem cells from the absorbed fluids and cells removed from the intrauterine device.14. The method of claim 13 , wherein the fluids and cells are removed from the intrauterine device while the intrauterine device is in place in the intrauterine cavity.15. The method of claim 13 , wherein the fluids and cells are removed from the intrauterine device ...

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Номер записи: 57
05-01-2017 дата публикации

INTEGRATED TESTING DEVICE

Номер: US20170001192A1
Автор: DUNN Christopher David, HUESO Ernesto Monis, JOHNSON Ian Frederick, KELLY John Michael, NORCOTT Alison Ruth, Sokolov Richard, SUI Eric
Принадлежит: ATOMO DIAGNOSTICS PTY LIMITED

An integrated testing device and method are disclosed. The device includes an integral reservoir for a test fluid, and an actuator, so that the test fluid can be dispensed to facilitate the test. 1. An integrated testing device comprising:a test component;a reservoir adapted to contain a test fluid; anda fluid delivery actuator, wherein operation of the fluid delivery actuator causes the test fluid to be released from the reservoir so as to contact the test component.2. An integrated testing device according to claim 1 , wherein the device further includes a receptacle for receiving a bodily fluid claim 1 , so that the bodily fluid contacts or can be caused to contact the test component.3. An integrated testing device according to claim 2 , wherein the actuator is adapted to be manually operated.4. An integrated testing device according to claim 1 , wherein an interlock prevents the release of the test fluid until a specific stage in the test process.5. An integrated testing device according to claim 4 , wherein an interlock prevents the release of the test fluid until the bodily fluid has contacted the test component.6. An integrated testing device according to claim 1 , wherein the test component is removable from the diagnostic system.7. An integrated testing device according to claim 1 , wherein the actuator is adapted to enable the release a controlled amount of test fluid.8. An integrated testing device according to claim 1 , wherein the device comprises a plurality of reservoirs adapted to contain test fluids.9. An integrated testing device according to claim 1 , wherein the or each reservoir is a separately formed sachet.10. An integrated testing device according to claim 9 , wherein the sachet is formed so that when pressure is applied by the actuator claim 9 , test fluid is emitted from a specific site on the sachet.11. Am integrated testing device according to claim 10 , wherein the actuator comprises a button located on the housing of the device.12. An ...

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Номер записи: 58
03-01-2019 дата публикации

SYSTEM AND METHOD FOR DESORBING AND DETECTING AN ANALYTE SORBED ON A SOLID PHASE MICROEXTRACTION DEVICE

Номер: US20190003936A1
Автор: Pawliszyn Janusz, Singh Varoon, Tascon Marcos
Принадлежит:

Disclosed herein is a system for desorbing and detecting an analyte sorbed on a solid phase microextraction (SPME) device. This SPME device The system includes a desorption chamber containing solvent required for desorption of analytes from SPME device; a flow injector in fluid connection with the desorption chamber, the desorption chamber and the flow injector being fluidly connected by at least a flow-insulating fluid connector; a solvent source in fluid connection with the flow injector; and a fluid switch that: in a desorption position, allows the solvent to be sprayed from the flow injector while flow-insulating any desorption solution in the desorption chamber, and in an detecting position, turns off the solvent source while maintaining the fluid connection between the flow injector and the desorption chamber, transferring the desorption solution through the flow-insulating fluid connector to the flow injector as a substantially undiluted plug of liquid. The SPME device can be configured to be various morphologies such as, fibers, blades, thin film membranes and even magnetic particles. When magnetic particles are used an additional holder that contains an embedded magnet which holds a plate with a well to hold said magnetic particles is added to the system. 1. A system for desorbing and detecting an analyte sorbed on a solid phase microextraction (SPME) device , the system comprising:a desorption chamber containing the desorption fluid forming a dome in contact with said SPME device;a flow injector in fluid connection with the desorption chamber, the desorption chamber and the flow injector being fluidly connected by at least a flow-insulating fluid connector;a solvent source in fluid connection with the flow injector; and (a) in a desorption position, allows the solvent to be sprayed from the flow injector while flow-insulating any desorption solution in the desorption chamber, and', '(b) in an detecting position, isolates the solvent source from the flow ...

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Номер записи: 59
01-01-2015 дата публикации

Analyte meter with operational range configuration technique

Номер: US20150006087A1
Автор: Shawn Berven, Sweta CHOVANDA
Принадлежит: Lifescan Inc

Described are techniques governing the glycemic ranges that are applied and governed in the meter so the user is not required to understand or know the editing rules in order to use or set up the meter. These guiding principles will come into effect each time the user chooses to edit the ranges. There will be appropriate warning messages to inform the user if the user does not set the ranges correctly.

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Номер записи: 60
12-01-2017 дата публикации

ASSEMBLY FOR DETERMINING THE PRESENCE OR ABSENCE OF AN ANALYTE IN A BLOOD SAMPLE AND ANALYSIS UNIT COMPRISING SUCH AN ASSEMBLY

Номер: US20170007164A1
Автор: Colin Bruno, Goudard Michel, Paris Cecile
Принадлежит: BIOMERIEUX

This assembly includes: a transportable support; a strip attached to the support and including an application area for applying the sample and at least one reagent required for the analysis; a piercing member for piercing the skin and a blood vessel; and a container for collecting, storing and returning the sample of human or animal blood. The piercing member is inserted into the container. The tip is connected to the support. The container is connected to the support in a removable manner between a storage configuration and a use configuration, in which the container is placed close to the application area. 1. An assembly comprising:a casing configured to be transportable by hand;a strip attached to and arranged inside the casing, the strip comprising an application area for a blood sample and at least one reagent for a blood analysis;a piercing member connected to the casing and configured to pierce skin or a blood vessel; anda container configured to collect, store, and provide the blood sample to the strip, the container being removably connected to the casing such that the container may be alternatively arranged in a storage configuration or in a use configuration, in which the container may be placed close to the application area.2. The assembly according to claim 1 , further comprising:a piece of fabric which is soaked in disinfectant product and which is extends over an outer surface of the casing; anda sealed film, detachable and watertight, the film being arranged such as to cover the piece of fabric when the container is arranged in the storage configuration.3. The assembly according to claim 1 , configured such that when the container is arranged in the storage configuration claim 1 , the container and the piercing member are each connected to the casing.4. The assembly according to claim 3 , configured such that when the container is arranged in the storage configuration claim 3 , the piercing member is either totally or partially housed within a hollow ...

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Номер записи: 61
14-01-2021 дата публикации

Medical device inserters and processes of inserting and using medical devices

Номер: US20210007651A1
Автор: Louis G. Pace, Manuel Luis Donnay, Peter G. Robinson, Tuan Nguyen
Принадлежит: Abbott Diabetes Care Inc

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

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Номер записи: 62
11-01-2018 дата публикации

DEVICES AND METHODS FOR BODY FLUID SAMPLING AND ANALYSIS

Номер: US20180008178A1
Автор: Bloom Daniel R., Escutia Raul, Hu Charles, Larkin John F., Reynolds Paul D., Tomasco Michael F., Vivolo Joseph A., Wiard Richard M.
Принадлежит:

Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member. 114-. (canceled)15: A body fluid sampling arrangement comprising:a hub comprising a patterned surface, wherein the patterned surface defines a volume;a skin penetration member configured to pierce skin and comprising a bore therethrough, wherein the bore is in fluid communication with the patterned surface; anda quantification member configured to react with a body fluid sample,wherein the hub is configured to collect the body fluid sample in the volume, and when the volume is filled, deliver the body fluid sample to the quantification member.16: The arrangement of claim 15 , wherein the volume is a volume sufficient to provide a measurable result indicative of a property of the body fluid sample.17: The arrangement of claim 16 , wherein the body fluid sample is blood and the property of the body fluid sample is a concentration of glucose.18: The arrangement of claim 15 , wherein the patterned surface is configured to spread the body fluid sample so that it is positioned across a surface of the quantification member prior to contacting the quantification member.19: The arrangement of claim 15 , wherein the bore is centrally positioned relative to the patterned surface and the patterned surface is configured to promote spread of the body fluid sample radially across the patterned surface.20: The arrangement of claim 15 , wherein the patterned surface comprises a groove or a channel configured ...

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Номер записи: 63
11-01-2018 дата публикации

Blood Collection Tube Holder with Discharge Needle Displacement Member

Номер: US20180008180A1
Автор: Shaw Thomas J., Small Mark
Принадлежит:

A medical device configured as a blood collection tube holder, the device having a body with two spaced-apart, oppositely facing, coaxially aligned needles including a forwardly facing venipuncture needle and a rearwardly facing fluid discharge needle, the two needles being held by first and second needle holders separated by a compressible fluid seal defining part of a fluid path between the two needles and the two needle holders. The body also includes a discharge needle displacement member that is manually repositioned following removal of the last blood tube holder so that the discharge needle displacement member contacts the second needle holder and displaces the second needle holder and the fluid discharge needle laterally inside the body to initiate retraction of the venipuncture needle into a rearwardly projecting needle retraction chamber. 1. A blood collection tube holder comprising:a body;two spaced-apart, oppositely facing, coaxially aligned needles held inside the body, wherein the first needle is a forwardly projecting venipuncture needle held by a rearwardly biased needle holder and the second needle is a rearwardly facing fluid discharge needle;a discharge needle displacement member slidably engaging the body and further comprising a rearwardly projecting needle retraction chamber and a touch surface configured to initiate sliding movement of the discharge needle displacement member relative to the body;wherein sliding movement of the discharge needle displacement member relative to the body displaces the fluid discharge needle laterally relative to the venipuncture needle, allowing the rearwardly biased needle holder to travel into the rearwardly projecting needle retraction chamber so that the venipuncture needle no longer projects forwardly from the body.2. The blood collection tube holder of wherein the rearwardly biased needle holder comprises part of a fluid flow path communicating with the venipuncture needle.3. The blood collection tube ...

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Номер записи: 64
11-01-2018 дата публикации

DEVICES AND METHODS FOR DELIVERING AND/OR RECEIVING FLUID

Номер: US20180008183A1
Автор: Chickering, Chu Li Yang, Grigoryants Sergey, III Donald E., James Scott, Wachlin Jacob
Принадлежит: Seventh Sense Biosystems, Inc.

The present invention generally relates to collecting, determining and/or transmitting information associated with the process of receiving bodily fluid through a device opening and/or delivering substances to a subject. In one aspect, the device includes an information collecting portion and a fluid receiving portion. In another aspect, the two portions are constructed and designed to attach to one another. In one embodiment, actuation of one of the portions causes the other portion to actuate. Methods of time keeping and information transmission are also discussed. 1. A device for receiving fluid from a subject , comprising:a device actuator;a fluid receiving portion constructed and designed to receive fluid from the subject, the fluid receiving portion including a fluid storage chamber for storing the fluid released by the subject;an information collecting portion being constructed and designed to attach to the fluid receiving portion, the information collecting portion being constructed and designed to collect information associated with operation of the fluid receiving portion or the fluid stored in the storage chamber,wherein activation of the device actuator actuates the fluid receiving portion to begin a fluid collecting process and actuates the information collecting portion to collect information.2. The device of claim 1 , wherein:the information collecting portion comprises a housing having sidewalls,the fluid receiving portion comprises a housing, andwhen the information collecting portion is attached to the fluid receiving portion, the sidewalls surround at least a portion of the housing of the fluid receiving portion.3. The device of claim 2 , wherein the housing of the information collecting portion attaches to the housing of the fluid receiving portion via a snap-fit engagement.4. The device of claim 1 , wherein all electronic components of the device are contained only within the information collecting portion.5. The device of claim 1 , wherein the ...

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Номер записи: 65
10-01-2019 дата публикации

METHOD OF HARVESTING TISSUE USING SEQUENTIAL SECTIONS OF A TWO DIMENSIONAL ARRAY OF NEEDLES

Номер: US20190008542A1
Автор: Guiles Marvin A., Labombard Denis, Sabir Sameer, SIDOTI Charles
Принадлежит:

In one aspect, the present disclosure relates to a method for harvesting biological tissue. In some embodiments, the method includes providing a device having a plurality of segments of hollow tubes, each hollow tube having at least one point at the distal end of the hollow tube, the plurality of segments forming a two dimensional array of hollow tubes, wherein each segment can include a plurality of hollow tubes; positioning the two dimensional array of hollow tubes proximal to an upper surface of a biological tissue; advancing a first segment of the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from the surrounding tissue; raising the first segment of the two dimensional array of hollow tubes such that the biological tissue remains in each of the hollow tubes of the first segment; advancing a second segment of the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from the surrounding tissue; and raising the second segment of the two dimensional array of hollow tubes such that the biological tissue remains in each of the hollow tubes of the second segment. 1. A method for harvesting biological tissue , the method comprising:providing a device having a plurality of segments of hollow tubes, each hollow tube comprising at least one point at the distal end of the hollow tube, the plurality of segments forming a two dimensional array of hollow tubes, wherein each segment comprises a plurality of hollow tubes;positioning the two dimensional array of hollow tubes proximal to an upper surface of a biological tissue;advancing a first segment of the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from the surrounding tissue;raising the first segment of the two dimensional array of hollow tubes such that the biological tissue remains in each of the hollow tubes of the first segment;advancing a ...

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Номер записи: 66
14-01-2021 дата публикации

SYSTEMS AND METHODS FOR DELIVERING A FLUID TO A PATIENT WITH REDUCED CONTAMINATION

Номер: US20210008280A1
Автор: Bullington Gregory J., GAW Shan E., Patton Richard G.
Принадлежит: MAGNOLIA MEDICAL TECHNOLOGIES, INC.

An apparatus includes a cannula assembly, a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing includes an inlet port removably coupled to the cannula assembly and defines an inner volume. The fluid reservoir is fluidically coupled to the housing and configured to receive and isolate a volume of bodily fluid from a patient. The flow control mechanism is at least partially disposed in the inner volume. The actuator is operably coupled to the flow control mechanism and is configured to move the flow control mechanism between a first configuration, in which bodily fluid can flow, via a fluid flow path defined by the flow control mechanism, from the cannula assembly, through the inlet port and into the fluid reservoir, to a second configuration, in which the fluid reservoir is fluidically isolated from the cannula assembly. 1. An apparatus , comprising:a cannula assembly;a housing including a proximal end portion and a distal end portion and defining an inner volume therebetween, the housing having an inlet port configured to be removably coupled to the cannula assembly;a fluid reservoir fluidically coupled to the housing and configured to receive and isolate a first volume of bodily fluid withdrawn from the patient;a flow control mechanism at least partially disposed in the inner volume of the housing and configured to move relative to the housing between a first configuration and a second configuration, the flow control mechanism defining a fluid flow path between the cannula assembly and the fluid reservoir in the first configuration; andan actuator operably coupled to the flow control mechanism and configured to move the flow control mechanism from the first configuration in which the inlet port is placed in fluid communication with the fluid reservoir such that bodily fluid can flow from the cannula assembly, through inlet port via the fluid flow path and to the fluid reservoir, to the second configuration, in which the fluid ...

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Номер записи: 67
27-01-2022 дата публикации

MICRONEEDLE AND CHIP

Номер: US20220023606A1
Автор: Rangsten Pelle, Renlund Markus
Принадлежит:

A microneedle and a chip are disclosed for extraction fluids. The microneedle is provided on a substrate and comprises an elongated body extending from a distal end with a bevel to a proximal end on the substrate along a longitudinal axis. The elongated body comprises a capillary bore extending in a longitudinal direction thereof and defines a fluid path. The proximal end is integrally connected with the substrate and the capillary bore is in fluid communication with a fluid channel of the substrate. The cross-sectional area of the capillary bore in the distal end is larger than the cross-sectional area of the capillary bore in the proximal end. 1. A microneedle provided on a substrate , comprising: the elongated body comprises a capillary bore extending in a longitudinal direction thereof and defines a fluid path;', 'the proximal end is connected to the substrate and the capillary bore is in fluid communication with a fluid channel of the substrate;', 'wherein the cross-sectional area of the capillary bore comprises a triangular cross-section in a perpendicular direction relative the longitudinal direction of the microneedle., 'an elongated body extending from a distal end thereof with a bevel to a proximal end on the substrate along a longitudinal axis, wherein2. A microneedle according to claim 1 , wherein the triangular cross-section of the capillary bore further comprises at least one rounded corner.3. A microneedle according to claim 1 , wherein the triangular cross-section of the capillary bore comprises a convex base connected to straight sections via two rounded corners.4. A microneedle according to claim 1 , wherein the capillary bore comprises a hydrophilic surface.5. A microneedle according to claim 1 , wherein the fluid channel is configured to provide an under-pressure claim 1 , relative the atmospheric pressure claim 1 , to the capillary bore claim 1 , whereby fluid flow through the capillary bore is promoted.6. A microneedle according to claim 1 , ...

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Номер записи: 68
08-01-2015 дата публикации

Biocompatible Solid-Phase Microextraction Coatings and Methods for their Preparation

Номер: US20150011376A1
Автор: Florin Marcel Musteata, Janusz B. Pawliszyn, Mihaela L. Musteata
Принадлежит: Individual

A biocompatible coating, such as for a fiber, for solid phase microextraction (SPME) of a small molecule of interest from a matrix, with the coating having an extraction phase including SPME particles having pores dimensioned to absorb the small molecule of interest from the matrix and a biocompatible polymer being a polyacrylonitrile (PAN) or a co-polymer of polyacrylonitrile (PAN) that completely covers the SPME particles and homogeneously distributing the SPME particles therein and having reduced adsorption of proteins or macromolecules onto the SPME particles and allowing the SPME particles to extract the small molecule of interest from the matrix.

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Номер записи: 69
03-02-2022 дата публикации

CAPILLARY COLLECTOR WITH ROTATABLE CONNECTION

Номер: US20220031211A1
Автор: Bokka Srinivasa Rao Kishore K., Edelhauser Adam, Ivosevic Milan, Torris Anthony V., Yakhnich Vlad
Принадлежит:

A device for obtaining a blood sample, the device including a holder for receiving a sample source, the holder having an actuation portion and a port, a container engagement portion connected to the holder, and a collection container removably connectable to the container engagement portion, the container defining a collection cavity, wherein the container engagement portion allows the collection container to rotate between a first position in which the collection container is spaced from the port and a second position in which the collection container is in fluid communication with the port. 1. A device for obtaining a blood sample , the device comprising:a holder for receiving a sample source, the holder having an actuation portion and a port;a container engagement portion connected to the holder; anda collection container removably connectable to the container engagement portion, the container defining a collection cavity,wherein the container engagement portion allows the collection container to rotate between a first position in which the collection container is spaced from the port and a second position in which the collection container is in fluid communication with the port.2. The device of claim 1 , wherein the actuation portion is transitionable between a first position in which the holder defines a first ellipse and a second position in which the holder defines a second ellipse claim 1 , wherein the second ellipse is different than the first ellipse.3. The device of claim 1 , wherein the actuation portion includes a contact member.4. The device of claim 3 , wherein the actuation portion is transitionable between a first position in which the contact member is in a disengaged position and a second position in which the contact member is in an engaged position.5. The device of claim 4 , wherein claim 4 , with the contact member in the engaged position claim 4 , the contact member exerts a pressure on the sample source.6. The device of claim 1 , wherein the ...

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Номер записи: 70
19-01-2017 дата публикации

Passive safety i.v. blood collection catheter

Номер: US20170014061A1
Автор: Donald L. Millerd
Принадлежит: Millaghi Medical Inc

Apparatus and methods for a single, handheld device that provides for both insertion of a catheter and collection of a fluid. Some embodiments further include a needle that assists in the insertion of the catheter into a blood vessel, and which includes a retraction feature that protects the user from an accidental needle stick when the device is ready for disposal. Still further embodiments include a protective cover that prevents a user from accidentally being stuck by a second needle used for the introduction of the patient's blood into a collection device.

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Номер записи: 71
17-01-2019 дата публикации

SYSTEM, METHOD AND APPARATUS TO FACILITATE DRAWING BLOOD AND EXTRACTING OTHER BODILY FLUIDS

Номер: US20190015030A1
Автор: BARKER Michael James
Принадлежит:

A system, method and apparatus are provided for facilitating the extraction of bodily fluids, including blood, in a medical setting. The disclosed apparatus is configured as a single unit integral apparatus composed of two opposing and interconnected flexible clip components. A proximal end of a unitary apparatus includes two opposing flexible clip components configured to flexibly yet firmly engage a thumb or finger of the medical professional undertaking the blood draw in a manner that secures the apparatus to the thumb or finger of the medical professional during the blood draw evolution. A distal end of the unitary apparatus includes two opposing flexible clip components configured to flexibly yet firmly engage a blood tube holder of a typical standard diameter to securely hold the blood tube holder in place in proximity to the thumb or finger of the medical professional during the blood draw evolution. 1. A device to facilitate blood draw , comprising:a first substantially circular engaging portion that is configured to engage at least one of a thumb or a finger of a user; anda second substantially circular engaging portion that is configured to engage at least one of a blood tube holder or another substantially tubular shaped component,the first substantially circular engaging portion and the second substantially circular engaging portion being mechanically coupled to each other.2. The device of claim 1 , the first substantially circular engaging portion defining a first plane that is orthogonal to an axis at a center of the first substantially circular engaging portion claim 1 , and the second substantially circular engaging portion defining a second plane that is orthogonal to an axis at a center of the second substantially circular engaging portion.3. The device of claim 2 , the first substantially circular engaging portion and the second substantially circular engaging portion being mechanically coupled to each other in a configuration in which the first ...

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Номер записи: 72
17-01-2019 дата публикации

FLUID SAMPLING APPARATUS AND METHOD

Номер: US20190015031A1
Автор: LIEPOLD Darren Patrick, LIEPOLD Lars Otto
Принадлежит:

The present invention relates generally to a sampling apparatus and a method for bodily fluids, and, more specifically, a blood sampling apparatus and a method for using the same. A blood collection system includes a housing having at least one open end, and an absorbent material positioned within the housing. The absorbent material has at least one end positioned proximate the at least one open end of the housing. A method of collecting blood samples includes positioning an absorbent material near a source of blood, holding the absorbent material with a housing, the absorbent material absorbing a volume of blood, and moving the housing and absorbent material to a position where the absorbent material can dry. 1. A method of collecting blood samples comprising:positioning a absorbent material near a source of blood;holding the absorbent material with a housing, the absorbent material absorbing a volume of blood;moving the housing and absorbent material to a position where the absorbent material can dry.2. The method of further comprising shipping the housing and the absorbent material to a lab location.3. The method of wherein holding the sample with the housing includes:attaching the absorbent material to a stem; andattaching a stem to the housing, the length of the stem selected to position a portion of the absorbent material near an opening in the housing.4. The method of wherein holding the sample with the housing includes:attaching the absorbent material to a stem; andattaching a stem to a cap positioned over a first opening in the housing, the length of the stem selected to position a portion of the absorbent material near a second opening in the housing.5. The method of further comprising labeling the stem with an identifier.6. The method of further comprising:removing the stem and absorbent material from the housing; andmoving the stem and absorbent material using a robot, the stem and absorbent material moved to at least one different position to complete a ...

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Номер записи: 73
16-01-2020 дата публикации

CASSETTE FOR BLOOD SAMPLE MEASUREMENT COLLECTION AND STORAGE

Номер: US20200015725A1
Автор: Fink Catherine, Johnson Brandon T., Kopitzke Keith
Принадлежит:

A device uses push-initiated force to collect, meter, filter and store a blood sample. In one implementation, the push-initiated force may be provided in a cassette-type housing that also collects, meters, filters and/or stores the blood sample. 1. A blood sample collection device comprising:a housing;a collection well;a metering component coupled to the collection well for collecting a metered portion of the blood sample;absorptive media, disposed in a frame, adjacent to and in fluid communication with the metering component; anda movable member engaging an upper region of the collection well, and providing push-driven mechanical force to initiate collection of a blood sample onto the absorptive media.2. The device of wherein a breakable tab is disposed between the movable member and the frame supporting the absorptive media.3. The device of wherein a hinged cover is disposed over the collection well.4. The device of wherein the the metering component is disposed on on a substrate composed of two components that separate upon application of the mechanical force.5. The device of wherein the well and metering component form a subassembly that is disposed adjacent the frame containing the absorbtive media.6. The device of additionally wherein the absorbtive media is a microfluidic separation media for separating plasma from whole blood in the blood sample.7. The device of additionally comprising one or more supports for supporting the microfluidic separation media within the housing.8. The device of additionally comprising:an anticoagulant disposed within the metering component.9. The device of wherein the absorptive media is removable from the housing after application of the mechanical force.10. A device for collecting a fluid sample comprising:a sample port cover,a top housing,a fluid collection assembly,a bottom housing, anda frame assembly, whereinthe fluid collection assembly includes a sample port, an exit end, and one or more microfluidic channels disposed on ...

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Номер записи: 74
16-01-2020 дата публикации

RAPID DELIVERY AND/OR WITHDRAWAL OF FLUIDS

Номер: US20200015751A9
Автор: Bernstein Howard, Chickering, Davis Shawn, Haghgooie Ramin, III Donald E., Levinson Douglas A., Michelman Mark
Принадлежит: Seventh Sense Biosystems, Inc.

The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like. 1148-. (canceled)149. A device for receiving blood from a subject , the device comprising:a plurality of skin insertion objects for insertion into the skin of a subject, having a pre-deployed position and a deployed position; anda reversibly deformable structure, operably linkable to the plurality of skin insertion objects, the reversibly deformable structure switchable from a first position, through an actuation energy barrier, to a second position, wherein the first position is associated with the pre-deployed position of the skin insertion objects, and the second position is associated with the deployed position of the skin ...

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Номер записи: 75
21-01-2021 дата публикации

FLUID COLLECTION DEVICE AND RELATED METHODS

Номер: US20210015413A1
Автор: Dirckx Matthew, Singh Hardeep, Taylor Jason
Принадлежит: OPKO Diagnostics, LLC

Articles and methods for collecting and/or facilitating transfer of fluids are generally provided. In some embodiments, an article comprises a fluid collection region for introducing a fluid, such as a sample (e.g., blood sample) or a reagent, into a fluidic system. The articles and methods described herein may be useful for facilitating the filling of relatively small channels with a fluid, such as channels of a microfluidic device. The articles and methods may, for example, interface with a patient sample (e.g., a droplet of blood), or with a macroscopic fluid source such as a pipette or syringe. In certain embodiments, articles and methods described herein may increase the ease of collecting a fluidic sample from a patient, prevent or reduce spillage of the fluidic sample, reduce contamination of a fluidic sample, and/or prevent or reduce air from entering a fluidic sample or device compared to certain existing fluid collection devices. 1. An article for introducing a fluid into a fluidic system , comprising:a fluid collection region comprising an edge, a sidewall, and a bottom portion; anda receiving channel integrally connected to and in fluidic communication with the fluid collection region, wherein the receiving channel includes a concave portion adapted and arranged to receive a fluidic channel.2. An article as in claim 1 , wherein the edge is a curved edge.3. An article as in claim 1 , wherein the edge is tapered.4. An article as in claim 1 , wherein the receiving channel is adapted and arranged to receive a fluidic channel to allow fluid communication between the fluidic channel and the fluid collection region.5. An article as in claim 4 , wherein the fluidic channel is a part of a fluidic connector.6. A device for introducing a fluid into a fluidic system claim 4 , comprising:a fluidic connector comprising a fluidic channel that includes a fluid path having a fluid path inlet and a fluid path outlet, wherein the fluidic connector is adapted and arranged ...

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Номер записи: 76
16-01-2020 дата публикации

DELIVERY DEVICE FOR A VASCULAR ACCESS INSTRUMENT

Номер: US20200016374A1
Автор: Burkholz Jonathan Karl, Spataro Joseph
Принадлежит:

A delivery device for delivering an instrument into a catheter assembly may include a housing having a proximal end, a distal end, and a slot. The delivery device may include a guide feature, which may be disposed within the housing. The guide feature may extend through the slot. The delivery device may include an instrument disposed within the housing and extending through the guide feature. In response to movement of the guide feature along the slot in the distal direction a first distance, a first end of the instrument may be advanced in the distal direction a second distance, which may be greater than the first distance. A second end of the instrument may be stationary with respect to the housing. 1. A delivery device for delivering an instrument into a catheter assembly , comprising:a housing having a proximal end, a distal end, and a slot;a guide feature disposed within the housing, wherein the guide feature extends through the slot, wherein the guide feature comprises a channel, wherein the channel is generally U-shaped; andan instrument disposed within the housing and extending through the channel, wherein in response to movement of the guide feature along the slot in a distal direction, the instrument moves through the channel and a first end of the instrument is advanced in the distal direction, wherein a second end of the instrument is stationary with respect to the housing.2. The delivery device of claim 1 , wherein in response to movement of the guide feature along the slot in the distal direction a first distance claim 1 , the first end of the instrument is advanced in the distal direction a second distance claim 1 , wherein the second distance is greater than the first distance.3. The delivery device of claim 1 , wherein the first end of the instrument is advanced in the distal direction beyond the distal end of the housing in response to the guide feature being fully advanced along the slot in the distal direction.4. The delivery device of claim 1 , ...

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Номер записи: 77
22-01-2015 дата публикации

Near-field-communication or rfid based electrochemical biosensor and method for an ingredient measurement using thereof

Номер: US20150021207A1
Автор: Chong-Min Kyung, Hyun Tae Cho, Seung Ro Lee
Принадлежит: CENTER FOR INTEGRATED SMART SENSORS FOUNDATION

Disclosed herein are a near-field-communication or a Radio-Frequency Identification (RFID) based electrochemical biosensor capable of measuring an ingredient by being inter-worked with a wireless communication device such as a smartphone and a method for an ingredient measurement using thereof. The near field communication or radio-frequency identification based electrochemical biosensor, includes: a casing having a specimen introduction channel formed therein; an ingredient measurement electrode disposed in the casing and measuring a specific ingredient of a specimen; a reaction reagent portion disposed in the casing and reacting with the specimen; a specimen recognition electrode disposed in the casing and recognizing the introduction of the specimen; an antenna transmitting and receiving signals and power to and from a smart device or a tester; and a control integrated circuit (IC) chip controlling the ingredient measurement electrode, the specimen recognition electrode, and the antenna.

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Номер записи: 78
28-01-2016 дата публикации

DIAGNOSTIC TEST DEVICE WITH IMPROVED DISPLAY

Номер: US20160022225A1
Автор: Nazareth Albert R., Palmer Mathew, Romanoschi Ovieiu, Sanders Giles H.W., Snowden Timothy
Принадлежит:

The present disclosure relates to diagnostic test devices that provide enhanced communication to a user thereof through provision of improved digital display. The test device can include a test member, such as lateral flow assay test strip. The test device can further include an electronic communication circuit that can comprise a digital display element as well as a microcontroller. Other elements in the electronic communication circuit can include one or more sensor elements, an audio element, and one or more switching elements. The disclosure further relates to methods of providing indicia of operation of a test device that comprises steps for assembly of a diagnostic test device that includes an improved digital display. 1. A diagnostic test device comprising:a test member; andan electronic communication circuit adapted to provide one or more indicia of operation of the test member to a user;wherein the electronic communication circuit includes a color digital display.2. The diagnostic test device of claim 1 , wherein the color digital display comprises a plurality of color-variable pixels.3. The diagnostic test device of claim 1 , wherein the color digital display comprises one or more light emitting diode (LED).45-. (canceled)6. The diagnostic test device of claim 1 , wherein the color digital display comprises a liquid crystal display (LCD).710-. (canceled)11. The diagnostic test device of claim 6 , wherein the LCD comprises backlighting.12. The diagnostic test device of claim 1 , wherein the electronic communication circuit comprises a microcontroller.1323-. (canceled)24. The diagnostic test device of claim 1 , wherein the electronic communication circuit further includes an audio output component.25. (canceled)26. The diagnostic test device of claim 1 , wherein the test device is adapted to detect the presence of an analyte in a fluid sample applied to the test member.2728-. (canceled)29. A diagnostic test device comprising:a test member; andan electronic ...

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Номер записи: 79
26-01-2017 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE TRANSPORT

Номер: US20170020425A1
Автор: Chen Michael, Holmes Elizabeth A., Lui Clarissa, Young Daniel
Принадлежит:

Bodily fluid sample transport systems, devices, and method are provided. In at least one embodiment described herein, methods are provided for the physical transport of small volumes of bodily fluid in liquid form from one location to another location. By way of nonlimiting example, the samples are collected in liquid form at a collection site, transported in liquid form, and arrive at an analysis site in liquid form. In many embodiments, the liquid form during transport is not held in a porous matrix, wicking material, webbing, or similar material that prevents sample for being extracted in liquid form at the destination site. In one embodiment, small volume of sample in each sample vessel is in the range of about 1 ml to about 1 microliter. 169-. (canceled)70. A method comprising:collecting a bodily fluid sample on a surface of a subject, wherein the collected sample is stored in one or more sample vessels;providing a transport container to house at least two or more sample vessels, wherein the vessels are arranged in a two-dimensional array configuration in the transport container;arranging to have the sample vessels shipped in the transport container from a first location to a second location,wherein each of the sample vessels arrives at the second location holding a majority of its bodily fluid sample in a non-wicked, non-matrixed form that is removable from the sample vessels in liquid form and wherein the amount of sample in each of the sample vessels does not exceed about 2 ml; andscanning information storage units on substantially all of the sample vessels, wherein the scanning occurs while the sample vessels remain in the two-dimensional array configuration at the second location.71. The method of wherein collecting comprises making at least one puncture on the subject to release the bodily fluid claim 70 , wherein the puncture is not a venipuncture.72. The method of wherein collecting comprises using at least one lancet to make at least one puncture on ...

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Номер записи: 80
26-01-2017 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE COLLECTION

Номер: US20170020426A1
Автор: Burd Tammy, Chen Michael, Holmes Elizabeth A., Ko Pey-Jiun, Lath Adrit, McHale Patricia
Принадлежит:

Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container. 159-. (canceled)60. A device for collecting a bodily fluid sample , the device comprising:a first portion comprising at least two sample collection channels configured to capture bodily fluid sample formed on a surface of a subject by drawing the fluid sample into the sample collection channels via a first type of motive force;wherein each of the collection channels has at least one opening to allow air therein to be vented as sample enters therein; anda second portion comprising a plurality of sample containers for receiving the bodily fluid sample collected in the sample collection channels, the sample containers operably engagable to be in fluid communication with the collection channels, wherein the containers are configured to use a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channels into the containers.61. The device of claim 60 , wherein the at least two sample collection channels comprise molded channels formed in the first portion.62. The device of wherein said channels are configured to receive the bodily fluid sample from an interface on the first portion claim 60 , wherein the interface comprises a shaped front end configured to engage target ...

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Номер записи: 81
26-01-2017 дата публикации

Blood Collection Wristband

Номер: US20170020631A1
Автор: Horras Auston
Принадлежит:

A blood collection device includes a wristband with a base and a main body. The main body includes a plurality of tube openings that are sized and shaped to receive and hold blood tubes, and a hub opening that is sized and shaped to receive a hub. The hub opening includes a slot that allows a tube connected to the hub to be fed through the slot thereby obviating the need to fish the needle and butterfly through the entire length of the hub opening. This improves the safety of using a hub with an attached needle. In addition, by placing the hub and the blood tubes in a convenient place for the phlebologist, this further improves safety, speeds the blood drawing process and reduces the potential for work place injuries. 1. A blood collection system , comprising;a wristband;the wristband operatively connected to a main body;the main body having a top side, a bottom side, opposing ends and an opposing front side and back side;the main body having a plurality of tube openings;the tube openings extending from the front side of the main body to the back side of the main body;the main body having a hub opening;the hub opening extending from the front side of the main body to the back side of the main body;the hub opening having a slot therein, wherein the slot provides access to the hub opening.2. The blood collection system of claim 1 , wherein the tube openings are generally cylindrical in shape and slightly narrow as they extend from the front side to the back side of the main body.3. The blood collection system of claim 1 , wherein the hub opening is generally cylindrical in shape and slightly narrows as it extends from the front side to the back side of the main body.4. The blood collection system of claim 1 , further comprising a needle holder positioned in the main body.5. The blood collection system of claim 1 , further comprising a needle holder positioned in the main body claim 1 , wherein the needle holder is generally cylindrical in shape.6. The blood collection ...

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Номер записи: 82
10-02-2022 дата публикации

DEVICES, SYSTEMS AND METHODS FOR GRAVITY-ENHANCED MICROFLUIDIC COLLECTION, HANDLING AND TRANSFERRING OF FLUIDS

Номер: US20220039710A1
Автор: Berthier Erwin, Casavant Ben, Moga Ben
Принадлежит:

The disclosed apparatus, systems and methods relate to the collection of bodily fluids through the use of gravity and microfluidic properties by way of a collector. The collector can make use of microfluidic networks connected to collection sites on the skin of a subject to gather and shuttle blood into a reservoir by a combination of capillary action and gravitational forces. The collected fluid is moved through the microfluidic networks and into the reservoir by a variety of approaches. 120-. (canceled)21. A system for collecting bodily fluid from a subject , the system comprising:a housing including a base having (a) a lower surface configured to be positioned against skin of the subject and (b) an aperture extending therethrough;an outflow channel fluidly connected to the aperture and configured to receive a flow of the bodily fluid from the aperture; and the collection cartridge is fluidly connected to the portion of the outflow channel to receive the flow of the bodily fluid in the direction generally parallel to the lower surface of the base; and', 'the axis of the collection cartridge extends generally parallel to the lower surface of the base., 'an elongate collection cartridge extending along an axis, wherein the collection cartridge is configured to be releasably coupled to the housing via a coupling portion, wherein a portion of the outflow channel extends through the coupling portion in a direction generally parallel to the lower surface of the base, and wherein, when the collection cartridge is coupled to the coupling portion—'}22. The system of wherein the collection cartridge is configured to be sealingly coupled to the coupling portion.23. The system of wherein the collection cartridge includes a sealing member configured to sealingly engage a portion of the housing when the collection cartridge is coupled to the coupling portion.24. The system of claim 21 , further comprising a vacuum source positioned at least partially within the housing and ...

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Номер записи: 83
10-02-2022 дата публикации

BODY FLUID SAMPLING DEVICE - SAMPLING SITE INTERFACE

Номер: US20220039711A1
Автор: Emery Jeffrey L., Escutia Raul, Jones Jeffrey M., Lipman Kelley J., Litherland Craig M., Tomasco Michael F.
Принадлежит:

An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes: a housing, the housing comprising a first opening; a skin interface member disposed in the first opening, the skin interface member comprising an inner member having a second opening, and an outer member at least partially surrounding the inner member and attached to the first opening; and at least one skin-penetration member configured and arranged to project within the second opening. Arrangements having alternatively constructed skin interface members are also described. 148-. (canceled)49. An arrangement to assist in obtaining a body fluid sample from a sampling site of a user , the arrangement comprising:a housing; anda plate releasably mountable to the housing, the plate comprising a skin interface member attached thereto, the skin interface member comprising an inner member having an opening configured to receive the sampling site of a user, and an outer member at least partially surrounding the inner member, wherein the outer member is coplanar with the plate and is configured to flex more than the inner member upon application of force to the skin interface member.50. The arrangement of claim 49 , wherein the inner member has a first hardness and the outer member has a second hardness that is less than the first hardness.51. The arrangement of claim 49 , wherein the inner member and the outer member are integral.52. The arrangement of claim 49 , wherein the outer member is formed from an elastomer claim 49 , a silicone rubber claim 49 , or a soft plastic and the inner member is formed from a metal claim 49 , an elastomer claim 49 , or a ceramic.53. The arrangement of claim 49 , wherein the skin interface member comprises a punching or cutting mechanism.54. The arrangement of claim 53 , wherein the punching or cutting mechanism comprises a downwardly projecting member.55. The arrangement of further comprising a cartridge configured ...

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Номер записи: 84
10-02-2022 дата публикации

CATHETER AND RETRACTABLE NEEDLE WITH PURGING SYSTEM

Номер: US20220039712A1
Автор: Asbaghi Hooman A., Daniluck John V.
Принадлежит: MMI, LLC

Apparatus and methods pertaining to catheters used for the withdrawal of blood. 1. An apparatus for intravenous withdrawal of blood , comprising:a main body defining an interior;a catheter assembly having a body and a hollow lumen having a distal open end;a first hollow needle having a first sharp tip, said first needle being readily movable relative to said catheter assembly from a first extended position in which the first sharp tip extends from the distal open end of said lumen to a second retracted position in which the first sharp tip does not extend from the distal open end of said lumen;a second hollow needle having a second sharp tip extending in a direction opposite to the direction of the first hollow needle, said first hollow needle and said second hollow needle having a fluid flowpath therebetween;means for purging the fluid flowpath to the interior of said body; andmeans for restricting said purging means.2. The apparatus of wherein said restricting means is operative to restrict flow in the presence of blood.3. The apparatus of wherein said restricting means permits flow into the fluid flowpath.4. The apparatus of which further comprises means for biasing apart said first hollow needle and said catheter assembly.5. The apparatus of wherein said biasing mean is a spring.6. The apparatus of wherein said purging means permits flow in one direction and restricts flow in the opposite direction.7. An apparatus for collecting blood claim 1 , comprising:a main body defining an interior;a first retractable hollow needle having a first sharp tip extending distally, said first needle being movable from a first extended position in which the first sharp tip is exterior to said main body for insertion into a blood vessel to a second retracted position in which the first sharp tip is within the interior;a second hollow needle attached to said main body and having a second sharp tip extending proximally;a catheter assembly having a body and a hollow lumen and ...

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Номер записи: 85
24-01-2019 дата публикации

EXTENSION HOUSING A PROBE OR INTRAVENOUS CATHETER

Номер: US20190021640A1
Автор: Bihlmaier Bryan, Burkholz Jonathan Karl, Spataro Joseph
Принадлежит:

A vascular access device may include a housing, which may include a proximal end, a distal end, and a slot. The distal end of the housing may be configured to be coupled to a catheter assembly. The vascular access device may also include an instrument disposed within the housing. The instrument may include a catheter or a probe. The instrument may include a proximal end and a distal tip. The proximal end of the instrument may extend through the slot and may be configured to move along the slot to move the instrument from a proximal position to a distal position. In response to movement of the proximal end of the instrument from the proximal position to the distal position, the catheter may be advanced beyond the distal end of the housing into the catheter assembly and/or vasculature of a patient. 1. A vascular access device , comprising:a housing, comprising a proximal end, a distal end, and a slot; andan instrument disposed within the housing, wherein the instrument comprises a proximal end and a distal tip, wherein the instrument comprises a catheter or a probe, wherein the proximal end of the instrument extends through the slot and is configured to move along the slot from a proximal position to a distal position, wherein in response to movement of the proximal end of the instrument from the proximal position to the distal position, the instrument is advanced beyond the distal end of the housing.2. The vascular access device of claim 1 , wherein the instrument comprises the catheter claim 1 , wherein the proximal end of the instrument is coupled with an adapter claim 1 , wherein the adapter comprises a cavity configured to receive a syringe or blood collection tube claim 1 , wherein the adapter further comprises a cannula disposed within the cavity and configured to puncture a septum of the syringe or the blood collection tube in response to the syringe or the blood collection tube being advanced into the cavity of the adapter.3. The vascular access device of ...

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Номер записи: 86
24-01-2019 дата публикации

Intravenous Catheter Insertion and Blood Sample Devices and Method of Use

Номер: US20190022358A1
Автор: Belson Amir
Принадлежит:

A catheter insertion device includes a handle, a needle, a guide wire, and a catheter. The handle may have a proximal region and a distal region. The distal region may include a slot between a top extension and a bottom extension, which extends through a distal end. The needle may have a proximal end positioned in the proximal region and a distal end extending from the distal region. The guide wire may have a proximal end positioned in the proximal region of the handle and a distal end positioned in a lumen of the needle. The catheter may be positioned coaxially over the needle with a proximal end connected to a catheter hub. The catheter hub may be slidably disposed in the slot to enable movement from a first position in the distal region to a second position distal of the distal region. 1. A catheter insertion device , comprising:a handle having a proximal region and a distal region, the distal region including a slot between a top extension and a bottom extension, the slot extending through a distal end of the distal region;a needle having a proximal end positioned in the proximal region of the handle and a distal end extending from the distal region of the handle;a guide wire having a proximal end positioned in the proximal region of the handle and a distal end positioned in a lumen of the needle; anda catheter positioned coaxially over the needle, the catheter having a proximal end connected to a catheter hub, the catheter hub slidably disposed in the slot to enable movement from a first position in the distal region of the handle to a second position distal of the distal region.2. The catheter insertion device according to claim 1 , further comprising a guide wire advancement member coupled to the proximal end of the guidewire claim 1 , wherein movement of the guide wire advancement member moves the guide wire relative to the needle.3. The catheter insertion device according to claim 2 , wherein the guide wire advancement member includes a guide wire actuator ...

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Номер записи: 87
24-01-2019 дата публикации

SYSTEMS AND METHODS TO IMPROVE INSTRUMENT GUIDANCE WITHIN AN INTRAVENOUS CATHETER ASSEMBLY

Номер: US20190022367A1
Автор: Bihlmaier Bryan, Burkholz Jonathan Karl, Staley Shaun
Принадлежит:

A catheter assembly and/or an introducer may include one or more features configured to guide a probe and/or a catheter distally through a septum. The catheter assembly may include a catheter adapter and the septum. The catheter adapter may include a distal end, a proximal end, and a lumen extending therebetween. In some embodiments, the septum may be disposed within the lumen. The septum may include a proximal surface that is tapered inwardly in a distal direction such that the proximal surface of the septum is configured to guide the probe and/or the catheter distally through the septum. The catheter assembly may be configured to receive an introducer, which may include an introducer element. A proximal end of the introducer element may include another proximal surface that is tapered inwardly in the distal direction such that the other proximal surface is configured to guide the probe or the catheter distally through the septum. 1. A catheter assembly , comprising:a catheter adapter, comprising a distal end, a proximal end, and lumen extending therebetween; anda septum disposed within the lumen, wherein the septum comprises a proximal surface that is tapered inwardly in a distal direction such that the proximal surface is configured to guide a probe or catheter distally through the septum.2. The catheter assembly of claim 1 , wherein the septum comprises a cavity claim 1 , wherein a distal end of the cavity comprises an annular protrusion claim 1 , wherein annular protrusion forms the proximal surface.3. The catheter assembly of claim 2 , wherein the septum further comprises a slit disposed in a center of the annular protrusion.4. The catheter assembly of claim 1 , further comprising extension tubing claim 1 , wherein the proximal end of the catheter adapter comprises a first port and a second port claim 1 , wherein the lumen comprises a first lumen claim 1 , a second lumen claim 1 , and a common lumen claim 1 , wherein the first port forms the first lumen claim ...

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Номер записи: 88
28-01-2016 дата публикации

Device to Determine Volume of Fluid Dispensed

Номер: US20160025544A1
Автор: Dean Kamen, Derek G. Kane, John M. Kerwin, Larry B. Gray, Russell H. Beavis
Принадлежит: Deka Products LP

An apparatus for determining the volume of fluid dispensed. The apparatus has an acoustic volume sensor that acoustically excites a reference volume and a measurement chamber with a loudspeaker and measures the acoustic response with microphones acoustically coupled to the reference and the measurement chamber. The loudspeaker and sensing microphones are connected to the measurement chamber by separate ports. A detachable dispensing chamber is coupled to the acoustic volume sensor. The volume of the fluid dispensed is determined by a processor based on the acoustic response of the microphones to acoustic excitement by the loudspeaker.

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Номер записи: 89
26-01-2017 дата публикации

Method and apparatus for acquiring blood for testing

Номер: US20170023446A1
Автор: Gijsbertus G. Rietveld, Monika M. Kansal, Stuart Kushon
Принадлежит: NEOTERYX LLC

A blood sampling device is provided having holder with a manipulating end and an absorbent probe on the opposing end. The probe is made of pyrolyzed porous carbon sized to directly absorb a predetermined volume of liquid, preferably biological fluid, in a predetermined amount of time. Shapes for absorbent probes of differing materials are provided.

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Номер записи: 90
28-01-2016 дата публикации

HIGH THROUGHPUT DNA DAMAGE QUANTIFICATION OF HUMAN TISSUE WITH HOME-BASED COLLECTION DEVICE

Номер: US20160025709A1
Автор: Costes Sylvain V., Tang Jonathan, Yannone Steven M.
Принадлежит:

Kits, methods and systems for providing a service to provide a subject with information regarding the state of a subject's DNA damage. Collection, processing and analysis of samples are also described. 1. A home collection kit comprising a sterile blood-drawing device , a capillary blood collection device coated with an anti-coagulant to avoid coagulation , patient blood collection tubes containing a fixative and anti-coagulant , wherein the fixative provides fixation conditions such that the blood can be shipped and/or stored without substantial changes in the signal of interest (DNA-break markers).2. The kit of claim 1 , wherein said capillary blood collection device is configured to collect about 10 μl to about 200 μl claim 1 , or about 10 μl to about 100 μl of blood.3. (canceled)4. The kit of claim 1 , wherein said anticoagulant comprises EDTA or heparin.5. (canceled)6. The kit of claim 1 , wherein said fixative is selected from the group consisting of paraformaldehyde claim 1 , methanol claim 1 , ethanol claim 1 , acetone claim 1 , and urea.7. (canceled)8. The kit of claim 1 , wherein said fixative and anticoagulant in said blood collection tubes comprises:an anticoagulant;paraformaldehyde; anda buffer.9. The kit of claim 8 , wherein:said anticoagulant comprises about 10 mM up to about 100 mM EDTA; andsaid buffer comprises phosphate buffered saline at about pH 7 to about pH 8.1011-. (canceled)12. The kit of claim 8 , wherein said fixative comprises about 0.1 percent up to about 10% paraformaldehyde.13. The kit of claim 8 , wherein said fixative claim 8 , when mixed with blood leads to a mix of fixative and blood with a final concentration of 1% paraformaldehyde and 25 mM EDTA.14. The kit of claim 13 , wherein the fixative comprises about 2% paraformaldehyde and 50 mM EDTA in PBS claim 13 , and the volume of fixative provided in the collection tube is such that fixative and whole blood are mixed in a 1:1 ratio when the capillary collection device is dispensed ...

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Номер записи: 91
26-01-2017 дата публикации

Smartphone dock and diagnostic-test reader plus related methods

Номер: US20170023542A1
Автор: Jimmy Jing, Naishu Wang
Принадлежит: Individual

Disclosed is are a diagnostic test reader and related methods or systems. In one embodiment, a smartphone, including diagnostic software and a camera, may be docked onto the reader so that the camera of the phone is coupled to a diffuser for imaging test strips or other test cartridges provided to the reader. Preferably, the diagnostic software is configured to interpret an image of the strip and provide diagnostic feedback via the interface of the phone. Light for producing the image may be from the flash of the smartphone camera or a light source inside the reader. The more specific details of the disclosed reader are described in connection with the figures.

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Номер записи: 92
26-01-2017 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE COLLECTION, TRANSPORT, AND HANDLING

Номер: US20170023546A1
Автор: Anekal Samartha, Chen Michael, Holmes Elizabeth A., Lui Clarissa, Young Daniel
Принадлежит:

Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step. 1. A method for use with a bodily fluid sample from a subject , the method comprising:shipping a plurality of sample containers from a first location to a second location, wherein each of said sample containers contains about 500 μL or less but greater than about 30 μL of the bodily fluid sample, wherein interior volume of each of the sample containers is about 600 μL or less,subjecting the bodily fluid sample to a first accelerated sedimentation force of at least about 1400 g or greater to form a first processed sample;shipping the first processed sample from a first location to a second location; andsubjecting the first processed sample at the second location to a second accelerated sedimentation force of greater than about 10 g but less than about 500 g.2. (canceled)3. The method of wherein the first processed sample contains a heparin-based anti-coagulant.4. The method of wherein the first processed sample contains a plasma portion separated by a separation gel from a formed-blood component portion.5. The method of wherein the second processed sample does not force electrolytes though the separation gel from the formed-blood component portion to the plasma portion.6. The method of wherein the second processed sample does not force liquid though the separation gel from the formed-blood component portion to the plasma portion.7. The method of wherein the first accelerated sedimentation force is provided through centrifugation.8. The method of wherein the second accelerated sedimentation force is provided through centrifugation.9. The method of wherein a plurality of samples are shipped from a ...

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Номер записи: 93
23-01-2020 дата публикации

SKIN PRICK TEST DEVICE

Номер: US20200022629A1
Автор: MA Hance
Принадлежит:

The present invention relates to the field of test devices. The skin prick test device according the present invention mainly comprises conjoined bottles, a tray and pricking devices, wherein each set of conjoined bottles, which comprises a large bottle body and a small bottle body, is arranged in clamping holes of the tray, and liquid medicine can flow into the small bottle body from the large bottle body through an inclined surface, thereby avoiding frequent refilling of the liquid medicine. In addition, each connecting base has a trapezoidal cross section with its bottom surface being flush with that of the holder, and is gradually widened from the top down to fit with the parallel clamp plates on the tray, so that the pricking device has better stability as both ends thereof are prevented from excessively shaking longitudinally when the pricking device is taken out of and put into the tray. 1. A skin prick test device , comprising conjoined bottles , a tray and pricking devices , wherein clamping holes having the same as the conjoined bottles are arranged at an upper end of the tray , each set of conjoined bottles , which comprises bottle caps and bottle bodies , is arranged in the clamping holes; the bottle bodies comprise a first bottle body and a second bottle body which are of an integrated structure and internally communicated , and the first bottle body has a radius smaller than that of the second bottle body; each bottle body is provided with a pricking cavity inside and an opening at its upper end , the bottle cap is clamped and fixed to the opening at the upper end of the bottle body and is provided with a through hole corresponding to the position of the first bottle body , and the through hole is communicated with the pricking cavity; and protruding parallel clamp plates to which the pricking device is clamped are also arranged on an upper end surface of the tray.2. The skin prick test device according to claim 1 , wherein the pricking device ...

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Номер записи: 94
28-01-2021 дата публикации

MEDICAL DEVICE INSERTERS AND PROCESSES OF INSERTING AND USING MEDICAL DEVICES

Номер: US20210022654A1
Автор: Curry Samuel M., Donnay Manuel L., Nguyen Tuan, Pace Louis G., Robinson Peter G., Yee Phillip
Принадлежит:

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. 119-. (canceled)20. A glucose monitoring system comprising: the glucose sensor, wherein a distal end of the glucose sensor is configured to be inserted under skin of the subject;', 'a distal surface including an adhesive layer, wherein the distal surface is configured to be positioned on the skin of the subject such that the adhesive layer adheres to the skin of the subject;', 'an interior of the insertion assembly including a first spring in a loaded position, a second spring, a sliding member, and a straight track having a length, wherein the sliding member is configured to move only within the straight track; and', wherein the button is further configured to release the first spring from the loaded position upon being pressed, such that the first spring causes the sliding member to move within the straight track along a second axis different from the first axis, wherein the second axis is defined by the length of the straight track,', 'wherein movement of the sliding member within the straight track causes advancement of a sharp and the glucose sensor in a distal direction along an insertion axis different from the first axis and the second axis such that the distal end of the glucose sensor is inserted under the skin of the subject,', 'wherein the sliding member is further configured to continue moving within the straight track after the advancement of the sharp and the glucose sensor in the distal direction along the insertion axis,', 'wherein the second spring is configured to expand and retract the sharp in a proximal direction along the insertion axis while the distal end of the glucose sensor remains under the skin of the subject, and wherein expansion of the second spring does not stop before the sliding member has stopped moving,', 'wherein the second spring is a compression spring, and', 'wherein the glucose sensor is ...

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Номер записи: 95
28-01-2021 дата публикации

SYSTEMS AND METHODS FOR PHLEBOTOMY THROUGH A PERIPHERAL IV CATHETER

Номер: US20210022655A1
Автор: DEVGON Pitamber
Принадлежит: Velano Vascular, Inc.

An apparatus for performing phlebotomy through a peripheral intravenous line. The apparatus includes an introducer and a catheter configured to advance the catheter through a peripheral intravenous line. A y-adapter with a port of larger diameter is configured to receive the catheter and place in fluid communication with the peripheral intravenous line. When advanced the catheter is configured to transport a bodily fluid (i.e. blood) to a volume outside of the body. 1. An apparatus , comprising:an introducer coupleable to a peripheral intravenous line, the peripheral intravenous line being at least partially insertable into a vein of a patient; anda catheter movable from a first position inside the introducer and outside the peripheral intravenous line to a second position at least partially outside the introducer and extending through the peripheral intravenous line, a proximal end of the catheter disposed in the introducer when the catheter is in the first position and the second position.2. The apparatus of claim 1 , further comprising:an actuator coupled to the proximal end portion of the catheter and movable along a fixed length of the introducer to move the catheter between the first position and the second position.3. The apparatus of claim 2 , wherein the introducer defines a slot claim 2 , the actuator being movable within the slot along the fixed length of the introducer.4. The apparatus of claim 1 , wherein the introducer is configured to transition between a first configuration and a second configuration to move the catheter between the first position and the second position.5. The apparatus of claim 4 , wherein the introducer has a first length when in the first configuration and a second length less than the first length when in the second configuration.6. The apparatus of claim 4 , wherein at least a portion of the introducer is collapsible from the first configuration to the second configuration.7. The apparatus of claim 1 , further comprising:an ...

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Номер записи: 96
28-01-2021 дата публикации

SAMPLING DEVICE INTERFACES

Номер: US20210022681A1
Автор: Bernstein Howard, Chickering, Davis Shawn, Haghgooie Ramin, III Donald E., Levinson Douglas A.
Принадлежит: Seventh Sense Biosystems, Inc.

The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, in some cases, may be interfaced with external equipment to determine an analyte contained within a fluid contained within or collected by the device. For example, the device may be mounted or engaged on an external holder, the device may include a port for transporting fluid out of the device, the device may include a window for interrogating a fluid contained within the device, or the like. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like. 187-. (canceled)88. A device for withdrawing blood from a subject , the device comprising:a recess comprising a fluid transporter, the fluid transporter comprising one or more needles;a detachable portion containing a storage chamber ...

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Номер записи: 97
29-01-2015 дата публикации

Stabilising and analysing fatty acids in a biological sample stored on solid media

Номер: US20150027208A1
Автор: Liu Ge, Robert Gibson
Принадлежит: ADELAIDE RESEARCH AND INNOVATION PTY LTD

The present invention relates to a method for stabilising fatty acids present in a sample such as bodily fluids. The present invention further relates to a solid medium which is capable of stabilising fatty acids applied thereto, and a method for preparing same. The present invention further relates to a method for determining the fatty acid composition of a sample.

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Номер записи: 98
24-01-2019 дата публикации

Test Sensor Cartridges And Sensor-Dispensing Instruments

Номер: US20190025278A1
Автор: Creaven John P., Reynolds Jeffery S.
Принадлежит:

The cartridge comprises a housing, a plurality of test sensors, a mechanical mechanism, and a pusher assembly. The housing forms at least one opening therethrough. The plurality of test sensors is stacked in the housing. The plurality of test sensors is adapted to assist in testing at least one analyte. The mechanical mechanism is adapted to urge the plurality of test sensors in a first direction. One of the plurality of test sensors is positioned for extraction from the cartridge. The pusher assembly is adapted to push one of the plurality of test sensors from the cartridge. The pusher assembly includes a ferromagnetic material or a magnet. 1187-. (canceled)188. A cartridge comprising:a housing forming at least one opening therethrough;a plurality of test sensors being stacked in the housing, the plurality of test sensors being adapted to assist in testing at least one analyte;a mechanical mechanism being adapted to urge the plurality of test sensors in a first direction, one of the plurality of test sensors being positioned for extraction from the cartridge; anda sliding pusher lid assembly including a flexible pusher tab, the flexible pusher tab being adapted to contact and push one of the plurality of test sensors from the housing and at least partially through the opening, the flexible pusher tab extending generally outwardly and generally downwardly from the remainder of the sliding pusher lid assembly,wherein in the closed position, the sliding pusher lid assembly is adapted to assist in sealing the cartridge.189. The cartridge of claim 188 , wherein the sliding pusher lid assembly further includes a pusher grip to assist in the user in gripping and sliding the pusher lid assembly.190. The cartridge of claim 188 , further including a reference surface that is adapted to contact the plurality of test sensors one at a time and assist in removing the plurality of test sensors one at a time.191. The cartridge of claim 188 , wherein the flexible pusher tab ...

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Номер записи: 99
04-02-2016 дата публикации

Analyte sensors, systems, testing apparatus and manufacturing methods

Номер: US20160029935A1
Автор: Jiangfeng Fei, Narasinha Parasnis, Serban Peteu, Swetha Chinnayelka, Yuan Wang
Принадлежит: Ascensia Diabetes Care Holdings AG

In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor may include one or more conductors received in a hollow portion of a hollow member. The first conductor may be made, at least in part, of a semiconductor material and an active region may be provided in contact with at least the first conductor. The analyte sensor may, in one aspect, include a lancet and an integrated sensor. Manufacturing methods and apparatus and systems utilizing the analyte sensors are provided, as are numerous other aspects.

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Номер записи: 100