14-01-2021 дата публикации
Номер: US20210008082A1
Fragrance compositions comprising one or more fragrance compounds for use in increasing the duration of sleep and/or improving quality of sleep in a subject is disclosed. Fragrance compositions comprising one or more fragrance compounds for use in increasing the quality of sleep in a subject (i.e., an increase in the time the subject is asleep during the night, a decrease in the time the subject is awake during the night, an increase in the time the subject experiences REM sleep, an increase in the time the subject experiences deep sleep, an increase in the time the subject experiences light sleep; and an increase in overall sleep efficiency) is disclosed. The composition can be incorporated into various consumer end products. 2. A method of improving at least one sleep parameter of a subject , wherein the method comprises:providing a fragrance accord; andadministering the fragrance accord to the subject in an amount effective to improve the at least one sleep parameter,wherein the at least one sleep parameter is selected from the group consisting of total minutes awake, total minutes asleep, sleep efficiency, number of REM sleep minutes, number of light sleep minutes, and number of deep sleep minutes.3. The method of claim 2 , wherein the fragrance accord comprises cis-3-hexenyl salicylate claim 2 , at least one musk compound and at least one floral compound.4. The method of claim 3 , wherein the musk compound is selected from the group consisting of (3aR claim 3 ,5aS claim 3 ,9aS claim 3 ,9bR)-3a claim 3 ,6 claim 3 ,6 claim 3 ,9a-tetramethyl-2 claim 3 ,4 claim 3 ,5 claim 3 ,5a claim 3 ,7 claim 3 ,8 claim 3 ,9 claim 3 ,9b-octahydro-1H-benzo[e][1]benzofuran claim 3 , 5-cyclohexadecen-1-one claim 3 , L-muscone claim 3 , (12E)-1-oxacyclohexadec-12-en-2-one claim 3 , and 1 claim 3 ,4-dioxacycloheptadecane-5 claim 3 ,17-dione.5. The method of claim 3 , wherein the floral compound is selected from the group consisting of myrcenol claim 3 , ionone alpha claim 3 , linalool ...
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