УСТРОЙСТВО И СПОСОБ ОПРЕДЕЛЕНИЯ ПОКАЗАТЕЛЕЙ ЖИЗНЕННО ВАЖНЫХ ФУНКЦИЙ ПАЦИЕНТА

Группа изобретений относится к медицине, а именно к определению информации о показателях жизненно важных функций пациента. Предложено устройство для реализации способа, причем устройство содержит: устройство обнаружения для обнаружения электромагнитного излучения, принимаемого от пациента в поле зрения устройства обнаружения, первый блок определения для определения первого, зависимого от времени сигнала плетизмографии из излучения, принятого от пациента, блок оценки для получения по меньшей мере одного параметра из первого зависимого от времени сигнала плетизмографии, причем блок оценки содержит устройство определения частоты или блок демодуляции для определения частоты из первого зависимого от времени сигнала плетизмографии по меньшей мере в качестве одного параметра, причем блок демодуляции является блоком частотной или амплитудной демодуляции для демодуляции первого, зависимого от времени сигнала плетизмографии как частотно-модулированного сигнала; блок выбора для выбора области в поле ...

АНАЛИЗАТОР ПУЛЬСОВОЙ ВОЛНЫ И СПОСОБ АНАЛИЗА ПУЛЬСОВОЙ ВОЛНЫ

Изобретение относится к медицине. Способ анализа пульсовой волны осуществляют с помощью анализатора пульсовой волны. При этом получают форму сигнала пульсовой волны одного сердечного сокращения посредством датчика давления. Преобразуют полученный сигнал в цифровой сигнал посредством блока цифрового преобразования. Получают форму сигнала производной четвертого порядка от исходной формы сигнала на основе преобразованного цифрового сигнала посредством дифференцирующего фильтра четвертого порядка. Посредством вычислительного устройства вычисляют точку экстремума формы сигнала производной четвертого порядка, секционируют форму сигнала пульсовой волны на зону отраженной волны и зону отсутствия отраженной волны и выделяют характеристическую точку зоны отраженной волны. При этом выделяют начальную точку зоны отраженной волны на основе точки экстремума формы сигнала производной четвертого порядка, выделяют конечную точку зоны отраженной волны на основе амплитуды формы сигнала производной четвертого ...

УСТРОЙСТВО И СПОСОБ ДЛЯ ИЗМЕРЕНИЯ НАСЫЩЕНИЯ КИСЛОРОДОМ КРОВИ В ТКАНИ ПАЦИЕНТА

Группа изобретений относится к медицинской технике. Раскрыты устройство и способ для неинвазивного определения насыщения кислородом крови в ткани пациента посредством спектроскопии в ближней ИК области с использованием мультидистанционного способа и с учетом ослабления светового сигнала, вызванного светопоглотителями иными, нежели гемоглобин и дезоксигемоглобин, а также светорассеивающих свойств ткани пациента. Устройство и способ, в частности, пригодны для измерения насыщения кислородом крови в брюшной полости новорожденных детей с учетом мекония, переходного стула и биливердина. 2 н. и 11 з.п. ф-лы.

Vorrichtung und Verfahren zum Detektieren eines Fahrerzustands basierend auf biometrischen Signalen des Fahrers

Eine Vorrichtung und ein Verfahren zum Detektieren von biometrischen Signalen eines Fahrers und Klassifizieren des Fahrers in einen Normalzustand oder einen Ermüdungszustand basierend auf den biometrischen Signalen sind vorgesehen. Eine derartige Vorrichtung kann aufweisen: einen biometrische-Signal-Messteil (100), der konfiguriert ist, um die biometrischen Signale einschließlich einer Blutflussrate im Gehirn des Fahrers mittels einer Elektroenzephalografie (EEG), einer Elektrokardiografie (EKG) und einer funktionellen Nahinfrarotspektroskopie (fNIRS) des Fahrers zu messen, einen biometrisches-Signal-Integrierteil (110), der konfiguriert ist, um die gemessenen biometrischen Signale zu integrieren, Charakteristiken der jeweiligen biometrischen Signale aus den gemessenen biometrischen Signalen zu extrahieren und die extrahierten Charakteristiken dann zu integrieren oder die extrahierten Charakteristiken der biometrischen Signale zu klassifizieren und dann die klassifizierten Charakteristiken ...

Messverfahren zur Erfassung von Vitalparametern am Körper eines Menschen oder eines Tieres und eine Messanordnung

Messverfahren (1) zur Erfassung von Vitalparametern am Körper eines Menschen oder eines Tieres, wobei in einem Erfassungsschritt (3) mit einem Magnetinduktionssensor eine Induktionsmessfolge erfasst wird, die von einer zeitabhängigen Änderung mindestens eines Vitalparameters abhängig ist, wobei in dem Erfassungsschritt (3) zeitgleich mit einer Zusatzsensoreinrichtung eine Zusatzmessfolge erfasst wird, wobei die Zusatzmessfolge von einer die Induktionsmessfolge beeinflussenden Einflussgrößensignalfolge abhängig ist und dass in einem nachfolgenden Kombinationsschritt (4) mit einer vorgegebenen Kombinationsfunktion aus der Induktionsmessfolge und der Zusatzmessfolge mindestens eine Vitalparametermessfolge für einen von der Induktionsmessfolge erfassten Vitalparameter berechnet wird, sodass eine Erfassungsgenauigkeit des in der Vitalparametermessfolge und der Induktionsmessfolge abgebildeten Vitalparameters durch die Kombination der Induktionsmessfolge und der Zusatzmessfolge in der Vitalparametermessfolge ...

Systems and methods for detecting contraband

Systems and methods for detecting contraband

Systems and methods for treating cardiac arrhythmia

Blood monitoring

Electrical impedance measurement and EIT image for location of a micro bio-channel under skin

A method for locating a variation in one or more electrical impedance properties of an object, the method comprising the steps of: obtaining electrical impedance data for the object at different locations; analysing the obtained electrical impedance data using a transfer function of an assumed electrical model to determine a variation of a plurality of electrical impedance properties for the object with location; and identifying a location identified by a variation of one or more of the plurality of electrical impedance properties. In embodiments the method finds particular use in electrical impedance tomography (EIT) for locating micro bio-channels, acupuncture points and the like.

A skin inspection device identifying abnormalities

A skin inspection device for identifying abnormalities comprises a transparent panel or window 102 having an inspection area; an array of thermochromic liquid crystal (TLC) formations 105 provided on the transparent panel which are operable to change colour in response to a change of temperature; and one or more image capture devices for capturing a colour image of the TLC formations and an area of skin of a target located in the inspection area; the captured colour image being analysed to identify abnormalities in the area of skin. Particularly of use in inspecting the feet of diabetic patients to prevent ulcer formation.

Electrocardiogra-based blood glucose level monitoring

Respiration from a photoplethysmorgram (PPG) Using fixed and adaptive filtering

Respiration from a photoplethysmorgram (PPG) Using fixed and adaptive filtering

A system to determine a respiration rate of a subject from an output of a device capable of generating a photoplethysmogram (PPG) signal (101). The system comprises one or more hardware-based processors (1201) to sample the PPG signal; a first high-pass (HP) filter to filter the sampled PPG signal; a second HP filter coupled in series with the first HP filter to receive an output from the first HP filter and to filter the output at a second selected frequency. The system further comprises a plurality of bandpass filters (Fig. 6A) to receive an output of the second HP filter and to determine a central frequency of various components of the PPG signal, wherein at least one of the processors is further configured to determine a spectral estimate of b, wherein b is a ratio of respiration rate to a pulse rate, from the central frequency, to determine the respiration rate.

Systems and methods for monitoring neural activity

Systems and Methods for Monitoring Neural Activity A method of monitoring neural activity responsive to a stimulus in a brain or a subject under general anaesthetic, the method comprising: applying the stimulus to one or more of at least one electrode implanted in a target neural structure of the brain; detecting a resonant response from the target neural structure evoked by the stimulus at one or more of the at least one electrode in or near the target neural structure of the brain; and determining one or more waveform characteristics of the detected resonant response.

MARKING A COMPUTERIZED MODEL OF A CARDIAC SURFACE

Described embodiments include a system that includes an electrical interface and a processor. The processor is configured 5 to receive, via the electrical interface, an electrocardiographic signal from an electrode within a heart of a subject, to ascertain a location of the electrode in a coordinate system of a computerized model of a surface of the heart, to select portions of the model responsively to the ascertained location, such that 0 the selected portions are interspersed with other, unselected portions of the model, and to display the model such that the selected portions, but not the unselected portions, are marked to indicate a property of the signal. Other embodiments are also described. 0c CC~j ...

Detecting conditions using heart rate sensors

This relates to methods for measuring irregularities in a' signal and corresponding devices. The devices can include, a PPG sensor unit configured to detect multiple occurrences of a given event in the measured signal(s) over a sampling interval, in some instances, the device can register the occurrences of the events. In some examples;, the device can Include one or more motion sensors configured to detect whether the device is in a low-motion, state. The device may delay initiating measurements when the device Is not in a low-motion state to enhance measurement accuracy. Examples of the disclosure further include resetting the sample procedure based on one or more factors such as the number of non-qualifying 'measurements, in some examples, the -device can be configured to perform both primary and secondary measurements, where the primary measurements can Include readings using a set of operating: conditions different from the secondary measurements.

Method for analyzing heart rate variability signal based on extremum energy decomposition method

The present invention discloses a method for analyzing a heart rate variability signal based on an extremum energy decomposition method, including: obtaining an ECG signal in an unknown state at a given time and a given sampling frequency, and performing denoising on the ECG signal, to obtain an RRI signal x(t); using the RRI signal x(t) as an original signal, decomposing the original signal x(t) into n extremum modal function components and one margin, representing components of the original signal in different frequency bands by using the n extremum modal function components obtained by decomposing the original signal x(t), and determining, based on the n extremum modal function components, whether the RRI signal is an abnormal heart rate variability signal. Based on the present invention, the RRI signal is analyzed by using the extremum energy decomposition method, the original signal is decomposed into a plurality of components, that is, an extremum component function, and energy of ...

A SYSTEM FOR LEADERSHIP SKILLS MEASUREMENT

Disclosed is a system and method for leadership skill measurement. The system comprises a computer program operable to display one or more random selection events to the individual on a display screen, wherein the computer system is operable to display the coherence score to the individual after the individual being submitted to a series of emotional stimuli. The system and method of the present invention provide a novel technique to scientifically measure leadership skills. Coherence is a standard metric in social cognitive neuroscience. Coherence is a measure of the level of interconnectedness different areas of the brain. High coherence in the right hemisphere is linked to greater emotional balance and understanding of one's own emotion as well as the emotions of others. It also reflects a greater cognitive understanding of the larger picture. In other words, the inspirational leader has a heighten Coherence in the right frontal hemisphere. Respondent is shown 3 neutral images 5 second ...

Automated methods and systems for vascular plaque detection and analysis

Method and system for noise cleaning of photoplethysmogram signals

METHOD AND SYSTEM FOR NOISE CLEANING OF PHOTOPLETHYSMOGRAM A method and system is provided for noise cleaning of photoplethysmogram signals. The method and system is disclosed for noise cleaning of photoplethysmogram signals for estimating blood pressure of a user; wherein photoplethysmogram signals are extracting from the user; the extracted photoplethysmogram signals are up sampled; the up sampled photoplethysmogram signals are filtered; uneven baseline drift of each cycle is removed from the up sampled and filtered photoplethysmogram signals; outlier cycles of the photoplethysmogram signals are removed and remaining cycles of the photoplethysmogram signals are modeled; and time domain features are extracted from originally extracted and modeled photoplethysmogram signals for estimating blood pressure of the user. [To be published with Figure 2] An up sampling module (206) An image capturing device (202) A filtering module (208) A baseline drift removal module (210) A mobile communication ...

Method and System for Rapid Acquisition of Evoked Compound Action Potential Recordings

According to an embodiment, a system for acquiring ECAP recordings at a later session for a cochlear implant patient is disclosed. The system includes a receiving unit configured to receive, corresponding to an electrode, a stored prior individual value from a plurality of stored 5 prior individual values of ECAP/ an ECAP prior growth function, the plurality of stored prior individual values or the ECAP prior growth function being obtained at a previous session. Furthermore, a processing unit configured to process the received prior individual value/ ECAP growth function to determine a stimulus signal value corresponding to the received individual value/ a selected point on the ECAP prior growth function, instruct a signal delivery unit to 10 provide to the electrode a first stimulus signal comprising a first level that is same or above said stimulus signal value, and determine a resulting ECAP generated in response to said first stimulus signal. (Figure 3 to be published) Receive stored ...

Methods and devices for monitoring respiration using photoplethysmography sensors

Provided in embodiments herein are computer-implemented methods and systems for respiratory monitoring. Some embodiments include obtaining a PPG signal stream from a central source site of the individual; identifying peaks and troughs of the PPG signal stream within a predetermined epoch, wherein a time between peaks or a time between troughs corresponds to a heart rate of the individual; determining significant local maxima of peak amplitudes and significant local minima of trough amplitudes within the predetermined epoch, wherein each significant local maxima of peak amplitude corresponds to an onset of the individual's respiratory effort to exhale and each significant local minima of trough amplitude corresponds to an onset of the individual's respiratory effort to inhale; calculating the number of significant local maxima, significant local minima, or both, during the predetermined epoch to determine the number of respiratory efforts in the predetermined epoch; and displaying the number ...

METHOD AND SYSTEM FOR DETERMINING POSTURAL BALANCE OF A PERSON

A method and system for determining postural balance of the person is provided. The disclosure provides a single limb stance body balance analysis system which will aid medical practitioners to analyze crucial factor for fall risk minimization, injury prevention, fitness and rehabilitation. Skeleton data was captured using Kinect. Two parameters vibration-jitter and force per unit mass (FPUM) are derived for each body part to assess postural stability during SLS. Further, the vibration and force imposed on each joint a first balance score was quantified. A first balance score and a second balance are also calculated by combining vibration index and SLS duration to indicate the postural balance of the person. The vibration index is computed from the vibration profile associated different body segments. [Abstract to be published with Fig. 1] E& z *z 0 0 ...

METHODS FOR ENABLING MOVEMENT OF OBJECTS, AND ASSOCIATED APPARATUS

A method for enabling movement of an object, having a plurality of degrees of freedom, by a user. The method comprising: receiving a first and second plurality of reference signals from first and second test subjects respectively, generated in response to respective reference intended movements; and determining a set of first of and second profiles. The method also comprises determining profile-pairs, which each comprise a first profile and a second profile that correspond to the same degree of freedom of the object; determining a reference set of profiles based on a mathematical combination of each profile-pair; and providing the reference set of profiles for determining an intended movement of the object based on a plurality of user signals received from a respective plurality of different sensors associated with the user. The intended movement comprises simultaneous movements with respect to at least two degrees of freedom of the plurality of degrees of freedom.

SYSTEM AND METHOD FOR DETERMINING BILIRUBIN LEVELS IN NEWBORN BABIES

The present invention provides a system and method for determining bilirubin levels in an individual based on skin coloration using a smartphone or other personal device and an attached ancillary apparatus. The device, such as a smartphone or tablet, is capable of storing and running software. The device is also coupled to both a camera and light source to obtain data regarding the skin's coloration. Software is installed on the device to control the light source and calculate bilirubin levels in the individual based on the input received from the camera. The ancillary apparatus is a mechanism surrounding the light source and camera that is placed on the skin of the individual when the system is in use. The ancillary apparatus thus creates a light tight seal between the skin, light source and camera, enabling the system to receive the most accurate data from the camera.

BIOMETRIC IDENTIFICATION SYSTEM USING PULSE WAVEFORM

A biometric identity confirmation system is based on pulse waveform data for the subject (20). During an initial enrollment mode, pulse waveform data for a known subject (20) are used to generate subject characterization data (23) for the known subject (20). The subject characterization data (23) includes an exemplar created by synchronous averaging of pulse waveform data over multiple puise cycles. A number of trigger candidates are identified for the start point of each pulse cycle. The time delay between trigger candidates is analyzed to discard faise trigger candidate and identify true candidates, which are then used as the start points for each pulse cycle in synchronous averaging of the pulse waveform data. During a subsequent identity authentication mode, pulse waveform data for a test subject (25) are analyzed using the subject characterization data (23) to confirm whether the identity of the test subject (25) matches the known subject (20).

PAIN MANAGEMENT

A system including a processor configured to be coupled to an electrical lead that is configured to sense electrical activity in a patient, a memory coupled to the processor, the memory containing computer readable instructions that, when executed by the processor, cause the processor to detect a pain signature in the sensed electrical activity, determine a treatment protocol in response to the detected pain signature, and cause the treatment protocol to be delivered to the patient via the electrical lead.

METHOD FOR MEASURING A PHYSIOLOGICAL PARAMETER, SUCH AS A BIOLOGICAL RHYTHM, ON THE BASIS OF AT LEAST TWO SENSORS, AND ASSOCIATED MEASUREMENT DEVICE

La présente invention concerne un procédé de mesure d'un paramètre physiologique tel qu'un rythme biologique à partir d'au moins deux capteurs ainsi qu'un dispositif de mesure associé et tel que le procédé comporte, selon l'invention, une étape de mesure du paramètre physiologique pour chaque capteur permettant de générer une série de mesures d'au moins deux valeurs, une étape d'évaluation du niveau de cohérence de chaque valeur de la série de mesures, une étape de sélection d'une valeur parmi l'ensemble des valeurs de la série en fonction d'une part de leur niveau de cohérence respectif et d'autre part d'une valeur dite de référence, afin de déterminer une nouvelle valeur de référence et une étape de stockage de la nouvelle valeur de référence.

PORTABLE DEVICE AND METHOD FOR ANALYSIS OF COMPOSITION OF INHALED AND EXHALED AIR SUBJECT

АВТОМАТИЗИРОВАННЫЕ СПОСОБЫ И СИСТЕМЫ ДЛЯ ОБНАРУЖЕНИЯ И АНАЛИЗА СОСУДИСТЫХ БЛЯШЕК

Предложены автоматизированные способы и системы для обнаружения и анализа бляшки в одной или более областей сосудистой системы пациента.

Blood pressure prediction method based on wavelet analysis and echo state network

Self-powered analyte sensor and devices using the same

Non-invasive blood glucose detection method based on minimally invasive blood glucose value calibration and detection device thereof

HEART RATE MEASURING METHOD AND APPARATUS, AND ELECTRONIC TERMINAL

Noninvasive continuous blood pressure measuring device

DEVICE AND METHOD FOR DETECTING MUSCLE ACTIVITY OF ONE OR MORE MUSCLES DEEP BY NON-INVASIVE MEASUREMENTS

Method and system for computation of start time of wave-free period for calculation of iFR for determination of treatment of intermediate coronary artery stenosis

APPARATUS AND METHOD FOR CALIBRATING GLUCOSE LEVEL

Smart clothes using biological signal processing

Method and System for Obtaining Cycle of Physiological Signal

... 본 발명은 일종의 생체신호주기의 획득 방법과 시스템을 제시한다. 해당 방법은 생체신호값을 수신한 후 임시값과 크기를 비교하여, 그중의 하나를 보류하며; 유지시간이 설정시간에 도달한 생체신호값을 하나의 극값으로 판정하며; 싸이클을 다시 시작하여 다음 극값을 판정하며; 어느 하나의 극값과 다음 극값사이의 시간값을 계산하는 것을 통해 생체신호주기를 획득하는 단계를 포함한다. 본 발명은 극값인식알고리즘을 통해 생체신호주기를 획득할수 있으며, 간단하고, 신속하고, 효율적이고 신뢰도가 높은 우점이 있고, 또한 생체신호의 증폭, 필터링 및 아날로그디지틀변환에 대한 요구가 상대적으로 낮고, 데이터처리가 상대적으로 용이하여, 하드웨에 비용을 대폭 줄일수 있다.

Animal disease management system using Internet of Things and its operation method

테라헤르츠 대역의 전자파를 이용한 인체 조직의 분석 방법 및 장치

... 테라헤르츠 대역의 전자파를 이용한 인체 조직의 분석 방법을 제공한다. 본 발명의 일 실시예에 따른 테라헤르츠 대역의 전자파를 이용한 인체 조직의 분석 방법은 테라헤르츠(THz) 대역의 전자파를 이용하여 인체 조직을 분석하는 방법에 있어서, 복소분수함수식(QCRF)을 이용하여 인체의 분산 특징을 주파수에 따라 변경되는 실수부 및 허수부로 나타낸 모델링인 QCRF모델링을 생성하는 단계; 소정의 제1 복셀(voxel) 크기를 갖는 기본인체모델에 기초하여, 상기 제1 복셀 크기를 소정의 비율로 변경한 제2 복셀 크기를 갖는 고해상도인체모델을 생성하는 단계; 및 맥스웰방정식을 이산화한 유한차분 시간영역(finite difference time domain; FDTD) 알고리즘, 상기 QCRF모델링 및 상기 고해상도인체모델에 기초하여, 상기 전자파의 인체 조직에 대한 작용 결과를 분석하는 단계를 포함한다.

APPARATUS AND METHOD FOR MEASURING BIO-INFORMATION

HEARING TEST METHOD AND APPARATUS BASED ON SPEECH DYNAMIC RANGE BY FREQUENCY BAND

INTELLIGENT SMART BAND FOR PROVIDING EMERGENCY NOTIFICATION THROUTH BIO SENSING

INFANT STATE TRANSMISSION SYSTEM

The present invention provides an infant state transmission system capable of checking an infant state in real time. According to an embodiment of the present invention, the infant state transmission system comprises: a heartbeat measuring part attached to a user, and measuring a heart rate of the user; a conductivity measuring part attached to the user, and measuring a skin conductivity of the user; a state determining part identifying a user state by using change of the heart rate and the skin conductivity; a transmitting part transmitting the unstable user state to a smart device; and a message playing part playing and transmitting voice or a video to the user. COPYRIGHT KIPO 2018 (10) Heart rate measuring part (20) Conductivity measuring part (30) State determination part (31) Conductivity determination part (32) Strength determination part (33) Irregular determination module (34) Speed determination module (40) Transmission part (41) Alarming transmission module (42) Video transmission ...

ELECTRONIC DEVICE AND CONTROL METHOD THEREOF

Provided are an electronic device capable of providing an accurate real-time measurement of blood glucose and a control method thereof. The electronic device for providing continuous blood glucose monitoring comprises: a first sensor for measuring a glucose level in interstitial fluids in order to predict a level of blood glucose; a second sensor disposed in the inner surface of the electronic device to come in contact with a human body and measure at least one of blood current and a heart rate of a human body; and a processor for determining a diffusion time, during which glucose present in blood is being diffused within the interstitial fluids, based on features of signals generated by the second sensor and predicting a level of blood glucose based on the level of glucose measured by the first sensor and the determined diffusion time. COPYRIGHT KIPO 2018 (AA) Start (BB) End (S1210) Determine blood glucose (S1220) Is that low blood glucose? (S1230) Determine step of low blood glucose and ...

METHOD, APPARATUS AND COMPUTER PROGRAM FOR MEASURING AND ANALYSIS OF BLOOD PRESSURE USING PHOTOPLETHYSMOGRAPHY

HIGH SENSITIVITY MULTIPLE BIO-SIGNAL ACQUISITION DEVICE AND HEALTHCARE METHOD USING SAME

A high sensitivity multiple bio-signal acquisition device and a healthcare method using the same are provided. According to an embodiment of the present invention, the bio-signal acquisition device includes: a band made of a stretchable material; and fabric electrodes provided on the band to detect the biological signals of a user. Thus, a fabric electrode for acquiring multiple biological signals can be formed on the band made of the stretchable material adhering to the wrist of the user, thereby increasing the sensitivity of the acquired signal by improving the contact property of the fabric electrode compared to an existing moving/attaching device, easily analyzing abnormal symptoms, and performing a fast and appropriate action. COPYRIGHT KIPO 2019 ...

METHOD FOR DETECTING BIOSIGNAL USING DIVERSITY TECHNIQUE AND BIO RADAR SYSTEM IMPLEMENTING THE SAME

HEALTH BAND TERMINAL

Provided is a health band terminal having a sensing module which is worn on a wrist to collect body composition information. The health band terminal comprises: a main body mountable in one area of the body; a first electrode part disposed on one side of the main body and having first and second electrodes disposed to be adjacent to each other; a second electrode part disposed on the other surface of the main body; and a control part calculating body composition information by using the impedance values measured by the first and second electrode parts. COPYRIGHT KIPO 2018 ...

WEARABLE DEVICE FOR HEART REHABILITATION EXERCISE AND CARDIAC REHABILITATION EXERCISE METHOD USING THE SAME

APPARATUS, METHOD AND APPLICATION FOR DIAGNOSING DEMENTIA

An apparatus for diagnosing dementia according to an embodiment of the present invention includes a database configured to store a first reference index set based on a standard alpha wave peak level obtained from a normal person′s EEG measurement signal, extracts an alpha wave peak level obtained from an EEG measurement signal of a subject as a first index, and compares the first index with the first reference index to diagnose the dementia. Accordingly, the present invention can perform an objective dementia diagnosis. COPYRIGHT KIPO 2018 (100) Dementia diagnosis apparatus (200) Brain wave sensing apparatus ...

BODY COMPOSITION ANALYZER HAVING MEASURED VALUE CORRECTING FUNCTION

The present invention relates to a body composition analyzer of a 4-electrode and 4-point touch type, which comprises: a mobile communications unit performing data communications with a mobile terminal of a measurer in a wired or a wireless manner; a measurer information storage unit storing measured basic information on the measurer including age, height, weight and gender received through the mobile communications unit; a BIA measurement unit measuring impedance of an upper body by providing a micro-AC, which is harmless to a human body, for the upper body through each touch pad; a first result calculating unit measuring a body composition including a body fat rate by using an impedance value measured by the BIA measurement unit and the measured basic information; a body feature determining unit determining one of four body types requiring correction for a measured value by using a standard body weight corresponding to the height of the measurer, the body weight of the measurer, and body ...

APPARATUS AND METHOD FOR MEASURING BIO-INFORMATION

Analyzing arterial pulse method and system thereof

An arterial pulse analyzing method and system thereof is disclosed. The method separates successive pulse signals into a plurality of pulses, and processes at least one of the pulses to obtain the non-time series data of at least one of the pulses. Then the non-time series data of at least one of the pulses is processed by a multi-model algorithm to obtain at least one features of at least one of the pulses.

Device and method for pulse diagnosis measurement

SYSTEM AND METHOD FOR THREE DIMENSIONAL CALIBRATION OF FORCE PLATES

A method for calibrating a force platform includes, providing a force platform and applying an nXm grid on a top surface of the force platform via a computing device. Next, applying p known loads on each of the nXm grid points of the top surface along a Z-axis being perpendicular to the X and Y axes and along the X and Y axes. Next, taking multipoint measurements at each grid point and for each applied known load along the X,Y and Z axes and generating six measured output signals, exact position coordinates and applied known load magnitude for each grid point. Next, assembling an array of nXmXp of six equations with six unknown for each grid point and applied known load and then solving the assembled equations and deriving a position and load specific calibration matrix for each grid point.

BLOOD WITHDRAWAL CANNULA OF A PUMP REPLACING OR ASSISTING ACTIVITY OF THE HEART

The invention relates to a blood withdrawal cannula (4) for connecting a pump (2) assisting or replacing activity of the heart to the inner volume of a heart ventricle (1), in particular the left ventricle. At the end thereof that is located in the ventricle the cannula has a pressure sensor (7a, 7b) for measuring the ventricle pressure and/or ventricle pressure differences and at the same end of the cannula has a volume sensor (3a, 3b, 5, 6) for measuring the volume and/or volume changes of the ventricle (1) in at least a partial region of the ventricle. The invention further relates to a measuring device for monitoring the ventricle contractions and/or the function of a pump replacing or assisting activity of the heart. The measuring device can be/is connected to the pressure sensor (7a, 7b) and to the volume sensor of a blood withdrawal cannula according to any one of the preceding claims and is designed to detect pressure changes and volume changes of a ventricle (1) as the heart is ...

IMAGING EPILEPSY SOURCES FROM ELECTROPHYSIOLOGICAL MEASUREMENTS

An example includes a method of imaging brain activity. The method includes receiving signals corresponding to neuronal activity of the brain. The signals are based on a plurality of scalp sensors (110). The method also includes decomposing the signals into spatial and temporal independent components (140). In addition, the method includes localizing a plurality of sources corresponding to the independent components. The method includes generating a spatio-temporal representation of neural activity based on the plurality of sources.

System and method for facilitating observation of monitored physiologic data

Present embodiments are directed to a system and method capable of detecting and graphically indicating physiologic patterns in patient data. For example, present embodiments may include a monitoring system that includes a monitor capable of receiving input relating to patient physiological parameters and storing historical data related to the parameters. Additionally, the monitoring system may include a screen capable of displaying the historical data corresponding to the patient physiological parameters. Further, the monitoring system may include a pattern detection feature capable of analyzing the historical data to detect a physiologic pattern in a segment of the historical data and capable of initiating a graphical indication of the segment on the screen when the physiologic pattern is present in the segment.

Detection and Display of Irregular Periodic Wave Forms

A method for display, consisting of acquiring an electrical signal from a heart of a subject over multiple heart cycles. The electrical signal is partitioned into a succession of synchronized segments having respective start times at a selected annotation point in the heart cycles. The method includes overlaying respective graphical representations of the synchronized segments in the succession on a display screen, such that each segment is first presented on the display screen with an initial display intensity at a respective display time corresponding to a respective start time of the segment. The method further includes gradually decreasing a display intensity of each segment overlaid on the display screen as a decaying function of a time elapsed since the respective display time.

METHOD AND SYSTEM FOR EVALUATION OF FUNCTIONAL CARDIAC ELECTROPHYSIOLOGY

An organ evaluation device, system, or method is configured to receive electrophysiological data from a patient or model organism and integrates the data in a computational backend environment with anatomical data input from an external source, spanning a plurality of file formats, where the input parameters are combined to visualize and output current density and/or current flow activity having ampere-based units displayed in the spatial context of heart or other organ anatomy.

Advanced electronic instrumentation for electrical impedance myography

Embodiments of devices and methods for evaluating tissue are disclosed. In one embodiment, a method for measuring a characteristic of a tissue may include passing a current through the tissue, measuring a signal corresponding to the voltage resulting from passing the current through the tissue, analyzing current passed through the tissue and resulting voltage to determine the electrical characteristics of the tissue; and analyzing the electrical characteristics of the tissue to determine a status of the tissue. Disposable sensors are disclosed.

HEART RATE DETERMINATION BASED ON VAD CURRENT WAVEFORM

The present disclosure provides for methods and systems for determining heart rate of a patient. Based on motor current signals of a ventricular assist device (VAD), each of first, second and third events in the measured current signal may be detected, the first event being indicative of a rise or fall in the current signal, the second event being indicative of a rise or fall in the current signal in the opposite direction as the first event, and the third event being indicative of a rise or fall in the current signal in the same direction as the first event. A timer counter may be initiated upon detection of the first event, and an elapsed time may be measured upon detection of the third event. Heart rate may be determined based on the elapsed time of the timer counter.

BODY ANALYZER

A body analyzer includes a main body including a platform contacting feet of a subject, an information transmitter, a weighing and body analyzing mechanism, a signal processor, and a wireless communication device, and a detecting board abutting against the subject's top head. At least one of the main body and the detecting board has a signal emitter, and at least one of the two has a signal receiver, thereby measuring a distance between the platform and the detecting board. The information transmitter emits data of the signal emitter and the signal receiver to the weighing and body analyzing mechanism. The weighing and body analyzing mechanism calculates body compositions of the subject. The signal processor processes data from the signal emitter, the signal receiver, and the weighing and body analyzing mechanism. The wireless communication device emits a processed data to an external mobile device or server via a wireless network.

Systems, apparatuses and methods for radio frequency-based attachment sensing

Some embodiments of the present disclosure discuss an apparatus comprising a transceiver configured to generate and/or receive radio frequency (RF) electromagnetic signals, one or more antennae configured to radiate the generated RF electromagnetic signals toward a surface and to output signals corresponding to received reflections of the RF electromagnetic signals, and a processing circuitry configured to process the received reflections and/or the output signals so as to determine change in position of the apparatus with respect to the surface. The apparatus may be incorporated into a wearable garment and/or an adhesive patch, and it may be attached to an outer surface of a human or an animal body.

DEVICE, SYSTEM AND METHOD FOR DETERMINING PULSE PRESSURE VARIATION OF A SUBJECT

The present invention relates to a device, system and method for determining pulse pressure variation of a subject. To enable more reliably determining pulse pressure variation of a subject the device comprises a signal input (11) configured to obtain an input signal representing a hemodynamic signal of the subject, a processor (12) configured to process the input signal and compute a pulse pressure variation and a signal output (13) configured to output the computed pulse pressure variation. The pulse pressure variation is computed by deriving a pulse height signal from the input signal, deriving a pulse height baseline and a de-trended pulse height signal from the pulse height signal as the ratio between the difference between extrema of the de-trended pulse height signal and the respective value of the pulse height baseline signal, and computing the pulse pressure variation from the de-trended pulse height signal and the pulse height baseline.

SYSTEM AND METHOD FOR AUDIO KYMOGRAPHIC DIAGNOSTICS

A system and method for assisting in a determination of one or more maladies associated with a human voice anatomy utilizes voice information acquired over at least two temporally displaced acquisitions. Acquired voice samples, including plural vowel sounds, are digitized and passed through one or more bandpass filters to isolate one or more frequency ranges. Curve fitting of acquired data is completed in accordance with a plurality of parameter weights applied in either a time domain or frequency domain model of the voice. This process is repeated a second, later time, for the same human, and the same process is completed for the subsequently-acquired voice information. A difference between the curve information in the respective data sets is analyzed relative to the weights, and corresponding changes are correlated to maladies of various areas of the human voice anatomy.

G-LOC WARNING METHOD AND SYSTEM USING G-LOC WARNING ALGORITHM

The present invention relates generally to a method for preventing gravity-induced loss of consciousness (G-LOC), which arises from increased acceleration during flight, and more particularly, to a G-LOC warning method and system using a G-LOC warning algorithm, which detects, in advance, risk factors that cause a G-LOC state by monitoring a change in the electromyogram (EMG) signal in real time. According to the G-LOC warning method and system using the G-LOC warning algorithm of the present invention, because information about the EMG signal is measured and collected in real time, changes in the EMG signal of a pilot who is exposed to high levels of acceleration during a flight maneuver are measured and checked on the spot.

Devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in cardio-pulmonary resuscitation (CPR) process

This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in the cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Respiration analysis using acoustic signal trends

The present invention isolates respiration phases in an acoustic signal using trend analysis. Once respiration phases are isolated, they are used to estimate respiration parameters. An exemplary method comprises receiving an acoustic signal recording body sounds; identifying candidate peaks at maxima of the signal; identifying candidate valleys at minima of the signal; selecting significant peaks from among the candidate peaks using heights of the candidate peaks; selecting significant valleys from among the candidate valleys using heights of the candidate valleys; detecting silent phases in the signal based at least in part on rise rates from the significant valleys; isolating respiration phases in the signal based at least in part on the significant valleys and the silent phases; calculating respiration parameter estimates based at least in part on the respiration phases; and outputting the respiration parameter estimates.

BIOLOGICAL INFORMATION ACQUISITION DEVICE, BIOLOGICAL INFORMATION ACQUISITION METHOD, AND RECORDING MEDIUM

According to the present invention, in a configuration in which a biological signal is received from an attachment-type device including one or more light emitting means and two or more light receiving means, information on a living body is acquired with high accuracy. A modulation unit (110) dims the one or more light emitting means with a specific frequency, a receiving unit (120) receives a biological signal based on the light received from a living body through the two or more light receiving means, and an adjusting unit (130) adjusts the intensity of the biological signal acquired from each light receiving means on the basis of the component of a specific frequency of the biological signal.

TRANSCRANIAL MAGNETIC STIMULATION SYSTEM AND METHOD

A transcranial magnetic stimulation system includes a magnetic field generator configured to generate a magnetic field to be applied to a patient's head, the magnetic field generator comprising one or more magnetic induction coils, a housing for the coils, and a Phase Change Material (PCM) in contact with the coils contained in the housing. One or more imaging devices configured to permit direct visualization of the coils on the patient's head are embedded in the housing. The one or more imaging device(s) may include one or more cameras, preferably one or more visible light imaging cameras, one or more ultraviolet light imaging cameras, or one or more infrared imaging cameras.

ОБНАРУЖЕНИЕ СИГНАЛА СО СНИЖЕННЫМ ИСКАЖЕНИЕМ

Изобретение относится к средствам извлечения информации из обнаруженного сигнала характеристики. Технический результат заключается в повышении точности извлечения информации. Принимается поток данных (26), извлекаемый из электромагнитного излучения (14), выпущенного или отраженного объектом (12). Поток данных (26) содержит непрерывный или дискретный контролируемый по времени сигнал характеристики (p; 98), содержащий по меньшей мере две основные составляющие (92a, 92b, 92c), связанные с соответствующими дополняющими каналами (90a, 90b, 90c) пространства сигналов (88). Сигнал характеристики (p; 98) отображается в заданное представление составляющей (b, h, s, c; T, c) с учетом по существу линейной алгебраической модели состава сигнала, чтобы задать линейное алгебраическое уравнение. Линейное алгебраическое уравнение по меньшей мере частично решается с учетом по меньшей мере приблизительной оценки заданных частей сигнала (b, h, s). Следовательно, из линейного алгебраического уравнения можно ...

УСТРОЙСТВО И СПОСОБ ОПРЕДЕЛЕНИЯ ОСНОВНЫХ ФИЗИОЛОГИЧЕСКИХ ПОКАЗАТЕЛЕЙ СУБЪЕКТА

Группа изобретений относится к медицине. Способ определения физиологического показателя субъекта осуществляют с помощью устройства для определения физиологического показателя субъекта. При этом с помощью интерфейса принимают поток данных, полученных из обнаруженного электромагнитного излучения, отраженного от исследуемой области кожной поверхности субъекта. Поток данных содержит информационный сигнал от области точечных элементов кожной поверхности. Информационный сигнал представляет обнаруженное электромагнитное излучение, отраженное от соответствующей области точечных элементов кожной поверхности в динамике по времени. С помощью анализатора проводят анализ пространственных и/или временных характеристик области кожной поверхности. Осуществляют определение гладкости, размера, однородности области кожной поверхности и/или составляющих сигналов цветности и/или яркости области кожной поверхности в динамике по времени и определение информации о надежности, используя изменение числа гладких ...

ИТЕРАЦИОННОЕ КОГЕРЕНТНОЕ КАРТИРОВАНИЕ ЭЛЕКТРОФИЗИОЛОГИЧЕСКОЙ АКТИВАЦИИ СЕРДЦА, ВКЛЮЧАЯ ЭФФЕКТЫ РУБЦА

ИТЕРАЦИОННОЕ КОГЕРЕНТНОЕ КАРТИРОВАНИЕ ЭЛЕКТРОФИЗИОЛОГИЧЕСКОЙ АКТИВАЦИИ СЕРДЦА, ВКЛЮЧАЮЩЕЕ В СЕБЯ ВЛИЯНИЕ ПОВТОРНОГО ВХОДА

Determination of cardiopulmonary resuscitation compression rate

A defibrillator (1) for determining a cardiopulmonary resuscitation (CPR) compression rate, comprising electrodes (3) adapted to be attached to the subject, an impedance signal measurement system (5) connected to the electrodes and configured to measure at least one impedance signal of the subject, an electrocardiogram signal measurement system (7) connected to the electrodes and configured to measure at least one electrocardiogram signal of the subject, an impedance signal processing system (9) connected to the impedance signal measurement system and configured to process the impedance signal of the subject to obtain a plurality of impedance signal compression rate estimates and a plurality of impedance signal features, an electrocardiogram signal processing system (11) connected to the electrocardiogram signal measurement system and configured to process the electrocardiogram signal of the subject to obtain a plurality of electrocardiogram signal features, a compression rate estimate ...

Personalized Nutritional and Wellness Assistant

Abstract The invention pertains to the establishment, implementation and management of a personalized information system pertinent to a user's general health, wellness and/or sport performance. Disclosed is a system capable of transcutaneous measurement of a subject including at least one light source, at least one light detector, and at least one component for generating or storing at least one value of VCO2 or at least one value of V02 from the detected signal. Further, disclosed is a portable device for analyzing the composition of the respired gasses of a subject including at least one air flow conduit through which the subject can inspire or expire air through the body of the device, at least one sampling portal, an oxygen sensor, and at least one flow sensor. A dual battery system is also provided by which an uninterrupted power supply can be provided for electronic components. 8519353_1 ...

System and method for facilitating observation of monitored physiologic data

Present embodiments are directed to a system and method capable of detecting and graphically indicating physiologic patterns in patient data. For example, present embodiments may include a monitoring system that includes a monitor capable of receiving input relating to patient physiological parameters and storing historical data related to the parameters. Additionally, the monitoring system may include a screen capable of displaying the historical data corresponding to the patient physiological parameters. Further, the monitoring system may include a pattern detection feature capable of analyzing the historical data to detect a physiologic pattern in a segment of the historical data and capable of initiating a graphical indication of the segment on the screen when the physiologic pattern is present in the segment.

Methods for assessing swallowing motor function

The present invention relates to methods for assessing swallowing motor function in a subject. The methods rely on obtaining intraluminal impedance and pressure measurements from the pharynx and/or esophagus of the subject during clearance of a bolus from the mouth and/or throat of the subject. The intraluminal impedance and pressure measurements are combined to derive a value for one or more pressure-flow variables in the pharynx and/or esophagus of the subject. The value of the one or more pressure-flow variables is compared to a predetermined pharyngeal and/or esophageal reference value for the one or more pressure-flow variables in order to provide an assessment of swallowing motor function in the subject. The intraluminal impedance and pressure measurements can also be combined to generate a swallow risk index for the subject or to generate an obstructive risk index for the subject based on a combination of a value of more than one pressure-flow variable in the pharynx and/or esophagus ...

Ultra-dense electrode-based brain imaging system

An ultra-dense electrode-based brain imaging system with high spatial and temporal resolution. A Sparsity and Smoothness enhanced Method Of Optimized electrical TomograpHy (s-SMOOTH) based reconstruction technique to improve the spatial resolution and localization accuracy of reconstructed brain images is described. Also described is a graph Fractional-Order Total Variation (gFOTV) based reconstruction technique to improve the spatial resolution and localization accuracy of reconstructed brain images.

Device and method for pulse diagnosis measurement

Abstract of Disclosure 5 A pulse diagnosis measurement device comprises a sensing device, for sensing a blood pressure wave of an organism, to generate a pulse signal; a pulse-holding device, for applying a pressure on a pulse of the organism, wherein the pulse holding device has an elasticity coefficient, the elasticity 0 coefficient is corresponding to a frequency of a harmonic of the blood pressure wave, and the harmonic is an integer harmonic or a fractional harmonic; and a processing device, for generating pulse diagnosis information of the harmonic according to the pulse signal. Sensing device Processing device Pulse-pressing device ...

Improved detection of action potentials

Separating a compound action potential from an artefact in a neural recording. A memory stores a set of basis functions comprising at least one compound action potential basis function and at least one artefact basis function. A neural recording of electrical activity in neural tissue is decomposed by determining at least one of a compound action potential and an artefact from the set of basis functions. An estimate is output of at least one of a compound action potential and an artefact.

Electrode patch, system, and method for detecting indicator of Pparkinson's disease in person

The present disclosure describes an electrode patch, and a method, a measurement arrangement, and a detection system utilizing the electrode patch for detecting an indicator of Parkinson's disease in a person from a muscle in a limb of the person. The electrode patch comprises two measurement electrodes, wherein a distance between centres of the measurement electrodes is above 2 cm and less than 4 cm, and a reference electrode positioned such that a lateral distance of from a centre of the reference electrode from to an axis passing through the centres of the measurement electrodes is at least he distance between the measurement electrodes.

ACCURATE TIME ANNOTATION OF INTRACARDIAC ECG SIGNALS

A method for analyzing signals, including: sensing a time-varying intracardiac potential signal and finding a fit of the time-varying intracardiac potential signal to a predefined oscillating waveform. The method further includes estimating an annotation time of the signal responsive to the fit. INSERT ELECTRODES. ACQUIRE ECG SIGNAL 202 200 SELECT HE ARTBEAT 4 FROM SIGNAL -20 FIT EQUATION TO 206 NO ELECTRODES YEN 2 Подробнее

DOUBLE BIPOLAR CONFIGURATION FOR ATRIAL FIBRILLATION ANNOTATION

Catheterization of the heart is carried out by inserting a probe having electrodes into a heart of a living subject, recording a bipolar electrogram and a unipolar electrogram from one of the electrodes at a location in the heart, and defining a window of interest wherein a rate of change in a potential of the bipolar electrogram exceeds a predetermined value. An annotation is established in the unipolar electrogram, wherein the annotation denotes a maximum rate of change in a potential of the unipolar electrogram within the window of interest. A quality value is assigned to the annotation, and a 3-dimensional map is generated of a portion of the heart that includes the annotation and the quality value thereof. ; ...

MAPPING OF ACTIVATION WAVEFRONTS

In one embodiment, a cardiac mapping system includes a medical examination device to capture data over time at multiple sample locations over a surface of at least one chamber of a heart, a display screen, and processing circuitry to process the captured data to determine a description of a propagation of activation wavefronts associated with activation times over the surface of the at least one chamber of the heart, calculate activation wavefront propagation path traces wherein each path trace describes a point on one activation wavefront being propagated over the surface of the at least one chamber of the heart according to an advancement of the activation wavefront such that the path traces describe the propagation of different points according to corresponding activation wavefronts, prepare a visualization showing the path traces on a representation of the at least one chamber, and render the visualization to the display screen.

BREAST SENSE FEEDING MONITOR

The Breast Sense Feeding Monitor provides real-time measurement of breastfeeding metrics including milk volume and infant suck and swallow characteristics over multiple feedings. The wearable design lends itself to versions suitable for both home and in-clinic use.

REFERENCE INTERVAL GENERATION

Described herein are systems and methods for generating health or risk parameter reference intervals for use in healthcare or any other application of risk/attribute measurement. The reference intervals generated by the systems and methods described herein are based on direct analysis and evidence-based models of human and/or other living organism data from a population of individuals including shared feature(s) and outcome data such as vital status. The direct analysis and evidence-based models of human and/or other living organisms data utilize shared common risk parameter feature(s) and outcome data and identify relationships of two or more health or risk parameters relative to one another. These methods also apply to the measurement of risk and/or other attributes of any living organism or nonliving objects.

CENTRAL AORTIC BLOOD PRESSURE AND WAVEFORM CALIBRATION METHOD

Central systolic and diastolic pressures are measured non-invasively using a peripheral senor to capture a patient's peripheral pulse waveform. Either the peripheral pulse waveform or a central pressure waveform generated, e.g., using a transfer method is recalibrated to account for differences between non-invasively measured systolic and diastolic pressure and invasively measured systolic and diastolic pressure. The recalibration is based, at least in part, on cardiovascular features of the patient's waveform. The determined central systolic and diastolic pressure values can be used to generate a corrected central pressure waveform having cardiovascular features preserved and maximum and minimum values set to the determined values.

CAMERA BASED PHOTOPLETHYSMOGRAM ESTIMATION

A system for estimating a photoplethysmogram waveform of a target includes an image processor configured to obtain images of the target and a waveform analyzer. The waveform analyzer is configured to determine a weight of a portion of the target. The weight is based on a time variation of a light reflectivity of the portion of the target. The time variation of the light reflectivity of the target is based on the images. The waveform analyzer is further configured to estimate a PPG waveform of the target based on the weight of the portion and the time variation of the light reflectivity of the portion.

CAMERA BASED PHOTOPLETHYSMOGRAM ESTIMATION

A system for estimating a photoplethysmogram waveform of a target includes an image processor configured to obtain images of the target and a waveform analyzer. The waveform analyzer is configured to determine a weight of a portion of the target. The weight is based on a time variation of a light reflectivity of the portion of the target. The time variation of the light reflectivity of the target is based on the images. The waveform analyzer is further configured to estimate a PPG waveform of the target based on the weight of the portion and the time variation of the light reflectivity of the portion.

A SKIN INSPECTION DEVICE FOR IDENTIFYING ABNORMALITIES

A skin inspection device for identifying abnormalities. The device comprises a transparent panel having an inspection area. An array of temperature sensors are provided on the transparent panel to record the temperature of an area of skin of a target. One or more image capture devices are provided for capturing an image of the area of skin of a target located in the inspection area. The captured image and recorded temperature being analysed to identify abnormalities in the area of skin of the target. A processor is operably coupled to the one or more image capture devices and the array of temperature sensors for controlling operations thereof. The processor is operable to generate indicia indicative of the emergence of ulcers and/or other skin abnormalities.

SYSTEM AND METHOD FOR FACILITATING OBSERVATION OF MONITORED PHYSIOLOGIC DATA

Present embodiments are directed to a system and method capable of detecting and graphically indicating physiologic patterns in patient data. For example, present embodiments may include a monitoring system that includes a monitor capable of receiving input relating to patient physiological parameters and storing historical data related to the parameters. Additionally, the monitoring system may include a screen capable of displaying the historical data corresponding to the patient physiological parameters. Further, the monitoring system may include a pattern detection feature capable of analyzing the historical data to detect a physiologic pattern in a segment of the historical data and capable of initiating a graphical indication of the segment on the screen when the physiologic pattern is present in the segment.

DEFIBRILLATOR DISPLAY

Systems and methods related to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR) are described herein.

Automated detection of sleep and waking states

Determining low power frequency range information from spectral data. Raw signal data can be adjusted to increase dynamic range for power within low power frequency ranges as compared to higher-power frequency ranges to determine adjusted source data valuable for acquiring low power frequency range information. Low power frequency range information can be used in the analysis of a variety of raw signal data. For example, low power frequency range information within electroencephalography data for a subject from a period of sleep can be used to determine sleep states. Similarly, automated full-frequency spectral electroencephalography signal analysis can be useful for customized analysis including assessing sleep quality, detecting pathological conditions, and determining the effect of medication on sleep states.

Metrics and algorithms for interpretation of muscular use

A muscle assessment method utilizing a computing system, surface electromyometry (sEMG) sensors, and other sensors to gather data for one or more subjects engaged in an activity through operably coupling the one or more sensors to the computing system, and directing a computing system to select one or more muscle assessment protocols related to a number of different metrics. For a user subject engaged in a physical activity, assessing muscle condition, the muscle activity, and statistically related averages provide information to the user and about muscle and whole body fitness.

Method and Apparatus For Early Warning of Critical Care Patient Hemodynamic Instability

A method and apparatus for providing a computing environment for a user which gives early warning of critical care patient instability. The method and apparatus use the entropy of monitored channels which are paired, each channel being paired once with each other channel. The entropies within each pair are compared to create an information exchange ratio. The information exchange ratios are integrated and a maximum of the integrated information exchange ratios is determined. Then, an alarm condition occurs at a user determined percentage of the maximum integrated information exchange ratio.

Signal Analysis System for Heart Condition Determination

A system for heart performance characterization and abnormality detection includes an interface for receiving sampled data representing an electrical signal indicating electrical activity of a patient heart over multiple heart beat cycles. A signal processor automatically, decomposes the received sampled data to multiple different subcomponent signals in the time domain. The signal processor associates individual decomposed subcomponents with corresponding different cardiac rotors and determined characteristics of the subcomponents indicating relative significance of the rotors in a cardiac atrial condition. A reproduction device provides data indicating the subcomponent characteristics indicating relative significance of the rotors in a cardiac atrial condition.

System and method for spo2 instability detection and quantification

The disclosed embodiments relate to a system and method for analyzing data. An exemplary method comprises the acts of receiving data corresponding to at least one time series, and computing a plurality of sequential instability index values of the data. An exemplary system comprises a source of data indicative of at least one time series of data, and a processor that is adapted to compute at least one of a plurality of sequential instability index values of the data.

Pain Management

A system including a processor configured to be coupled to an electrical lead that is configured to sense electrical activity in a patient, a memory coupled to the processor, the memory containing computer readable instructions that, when executed by the processor, cause the processor to detect a pain signature in the sensed electrical activity, determine a treatment protocol in response to the detected pain signature, and cause the treatment protocol to be delivered to the patient via the electrical lead.

Systems and methods for frequency-domain photoacoustic phased array imaging

Systems and methods of frequency-domain photoacoustic imaging are provided utilizing an ultrasonic phased array probe and intensity modulated optical excitation with coding to improve signal-to-noise ratio. Embodiments employ frequency-domain photoacoustic imaging methodologies such as the photoacoustic radar, coupled with a multi-element ultrasonic sensor array to deliver spatially-resolved correlation images of photoacoustic sources, which may be employed to image optical heterogeneities within tissue-like scattering media.

Accurate time annotation of intracardiac ecg signals

A method for analyzing signals, including: sensing a time-varying intracardiac potential signal and finding a fit of the time-varying intracardiac potential signal to a predefined oscillating waveform. The method further includes estimating an annotation time of the signal responsive to the fit.

METHODS AND APPARATUS FOR DETERMINING ARTERIAL PULSE WAVE VELOCITY

Methods are presented for determining pulse transit time (PTT) and/or pulse wave velocity (PWV) of a subject by application of parametric system identification to proximal and distal arterial waveforms. The two waveforms are measured from the subject. A system is defined that relates the proximal arterial waveform to the distal arterial waveform (or vice versa) in terms of the unknown parameters of a parametric mathematical model. The model parameters are determined from the measured waveforms using system identification. PTT between the proximal and distal arterial sites is then determined from the system model. PWV may also be determined by dividing the distance between measurement sites (D) by PTT. 126-. (canceled)27. A method for determining an arterial pulse transit time of a subject , comprising:measuring a proximal waveform indicative of the arterial pulse at a proximal site of the subject;measuring a distal waveform indicative of the arterial pulse at a distal site of the subject;defining a dynamic system that relates one of the waveforms to the other waveform in terms of unknown parameters of a parametric mathematical model that assumes a specific structure for the system;determining the unknown parameters of the mathematical model from the measured proximal waveform and the measured distal waveform; anddetermining a pulse transit time between the proximal site and the distal site from the mathematical model.28. The method of further comprises determining a distance between the proximal and distal sites and determining a pulse wave velocity by dividing the distance by the pulse transit time.29. The method of further comprises determining the unknown parameters by fitting one of the proximal waveform or the distal waveform to the other waveform.30. The method of wherein the mathematical model is a parametric physical tube-load model transfer function in which the pulse transit time is an explicit parameter of the model.31. The method of wherein the waveforms ...

SYSTEM AND METHOD FOR NON-INVASIVE DETERMINATION OF HEMOGLOBIN CONCENTRATION IN BLOOD

A system and method for measurement of absolute value of hemoglobin concentration non-invasively is provided. The system comprises a probe device comprising a sliding top structurally configured to be manually slid forward and backward onto the finger seat which is positioned on top of the housing for placing a fingertip. The finger seat houses two cavities for housing a set of three light emitting diodes and a photodetector respectively. Multiple distinct wavelengths of light transmitted through the fingertip is detected by the photodetector. Further, electronic signals generated by the photodetector are processed to obtain alternating and direct components of light corresponding to each wavelength. A system of three equations are obtained including unknown values of two primary constituent absorbers and known consolidated values of one or more secondary constituent absorbers corresponding to each wavelength of light. The system of equations are then solved simultaneously derive absolute value of hemoglobin concentration. 1. A method for non-invasively determining absolute value of hemoglobin concentration in blood , the method comprising:directing diffused light of three or more distinct wavelengths through a human tissue bed in a time-multiplexed manner;detecting optical signal corresponding to each wavelength by a photodetector and converting transmitted portion of optical signal into current signal;amplifying current signal corresponding to each wavelength of light to obtain a digital voltage waveform signal;processing the digital voltage waveform signal to obtain alternating and direct components of light corresponding to each wavelength;obtaining a system of three equations using alternating and direct components of light corresponding to each wavelength and Beer Lambert's law, wherein the equations comprise two unknown values of primary constituent absorbers of hemoglobin concentration and an unknown value of path length;deriving concentration values of the ...

BIOLOGICAL BODY STATE ESTIMATION DEVICE AND COMPUTER PROGRAM

A technique for grasping a state of a human being. The technique determines a time-series waveform of a frequency from a time-series waveform of a biological signal acquired from an upper body of a human being, and determines time-series waveforms of a frequency slope and frequency variation to analyze these frequencies. Upon analyzing the frequencies, it determines power spectrums of frequencies corresponding to a preset functional adjustment signal, fatigue reception signal, and activity adjustment signal, and then determines a state of the human being from a time-series change in each power spectrum. Dominant degrees of the functional adjustment signal and activity adjustment signal are compared as distribution rates thereof, in addition to a degree of progress of fatigue, to determine a state of the human being, for example a relaxed state, fatigued state, prominent state of sympathetic nervous, prominent state of parasympathetic nervous. 1. A biological body state estimation device which acquires a biological signal from an upper body of the human being and estimates a state of a human being by using the biological signal , comprising:frequency calculating means for determining a time-series waveform of a frequency from a time-series waveform of a biological signal acquired by the biological signal measuring means;frequency slope time-series analysis calculating means for subjecting the time-series waveform of the frequency of the biological signal acquired by the frequency calculating means to movement calculation for determining a slope of the frequency at each predetermined time window set with a predetermined overlap time, and for outputting a time-series change in the slope of the frequency acquired at each time window as a frequency slope time-series waveform;spectrum time-series change calculating means for analyzing a frequency of the frequency slope time-series waveform acquired by the frequency slope time-series analysis calculating means, and for ...

SYSTEM AND METHOD FOR THE SIMULTANEOUS, NON-INVASIVE ESTIMATION OF BLOOD GLUCOSE, GLUCOCORTICOID LEVEL AND BLOOD PRESSURE

System and method for the simultaneous and non-invasive estimation of blood glucose, glucocorticoid and pressure levels. It comprises an activity module detector for a digitalized signal acquired by a sensor, representing the distal heartbeat of a person, selecting a segment of consecutive signal samples of fixed duration S(t) and using the same to generate sub-windows S(t, n) of shorter duration; a signal processing module which receives the two signals S(t) and S(t, n) and which delivers a vector Xat its output with the parameters of a physiological model and module based on automatic learning, which receives the Xvector and information on a person's characteristics and provides an estimation of blood glucose levels (BGL), systolic pressure levels (SPL), diastolic pressure levels (DPL) and glucocorticoid levels (GCL) at its output. 1. System for the simultaneous and non-invasive estimation of glucose in blood , glucocorticoid levels and blood pressure , based on a person's distal heartbeat waveform , acquired from a sensor , which provides a digitalized signal , comprising:{'sub': window', 'frame', 'window, 'an activity detection module for said digitalized signal, which selects a segment of consecutive samples from said digitalized signal, with a fixed duration and which are referred to as S(t) and, based on the same, generates a sequence of sub-windows or frames referred to as S(t, n) which are shorter in duration than those of S(t), wherein the index t indicates the sample number within a frame and n represents the frame number;'}{'sub': window', 'frame', 'F, 'a signal processing module which receives the two signals S(t) and S(t, n) containing the waveform of the distal heartbeat in a fixed duration module, and which provides an Xvector as output, which in turn contains the parameters of a physiological model; and'}{'sub': 'F', 'an automatic learning based module to which said Xvector is fed alongside information on the characteristics of the person and which ...

Method and system for tomographic imaging

Approaches are disclosed for electrical impedance tomography which apply a current to a region at two or more frequencies and acquire voltage measurements at each frequency to generate a set of multi-frequency voltage measurements. One or more images of the region are generated, using spectral constraints, based on the multi-frequency data.

Adaptive phrenic nerve stimulation detection

An example of a system comprises a cardiac pulse generator configured to generate cardiac paces to pace the heart, a sensor configured to sense a physiological signal for use in detecting pace-induced phrenic nerve stimulation (PS), a storage, and a phrenic nerve stimulation detector. The storage is configured for use to store patient-specific PS features for PS beats with a desirably large signal-to-noise ratio. The phrenic nerve stimulation detector may be configured to detect PS features for the patient by analyzing a PS beat with a desirably large signal-to-noise ratio induced using a pacing pulse with a large energy output and store patient-specific PS features in the storage, and use the patient-specific PS features stored in the memory to detect PS beats when the heart is paced heart using cardiac pacing pulses with a smaller energy output.

Signal Data Extraction Method and Apparatus

A method and system for extracting important signal information is disclosed. The method examines a group of signals obtained from testing of a patient's nervous system and finds a signal area of interest. Once a cluster of signals that all have the area of interest is found—the system concludes that the area of interest is located and validated. Signals that are not within the cluster are rejected and the signals within the cluster are signal-averaged to yield a signal-averaged waveform. The signal averaged waveform represents the results of the test. 1. A method of constructing a waveform , said waveform representing the results of a test , comprising the steps of:obtaining a plurality of signals;storing said plurality of signals;analyzing said plurality of signals to identify a signal area of interest;obtaining a cluster of signals, each of said signals is said cluster of signal having said area of interest;calculating a percentage value for said cluster of signals, said percentage value corresponding to a percentage of signal having said area of interest out of total of said plurality of signals;determining if said percentage value is greater than a predetermined value; andconcluding, if said percentage value is greater than a predetermined percentage value, that said area of interest is validated.2. The method of claim 1 , further comprising the step of generating a signal-averaged waveform from said signals in said cluster of signals.3. The method of claim 1 , whereby said plurality of signals is obtained by one of VEP testing or PERG testing.4. The method of claim 1 , whereby said area of interest is a peak in said signal.5. The method of claim 1 , whereby said are of interest is a portion of a waveform that is found within a predetermined timeframe in a signal.6. The method of claim 3 , whereby said area of interest is a P100 latency.7. The method of claim 3 , whereby said area of interest is a P50 peak.8. The method of claim 1 , whereby said step of ...

SIGNAL AVERAGING

A method () can comprise performing principal component analysis (PCA) on data corresponding to a subset of a plurality of signals and a selected template to generate a virtual lead and an optimized template (). The method can also comprise calculating a cross correlation on the virtual lead and the optimized template to determine a strength of linear dependence between the virtual lead and the optimized template to determine regions of interest (ROIs) of the virtual lead (). The method can further comprise detecting peak correlation coefficients in the virtual lead (). The method can still further comprise comparing the amplitude of each of the ROIs of the virtual lead with the selected template to determine an error between the template and each ROI of the virtual lead (). The method can yet further comprise averaging the ROIs to generate averaged data (). 1. A method comprising:performing principal component analysis (PCA) on data corresponding to a subset of a plurality of signals and a selected template to generate a virtual lead and an optimized template, respectively, wherein each of the plurality of signals corresponds to an electrical biological signal detected by a sensor;calculating a cross correlation on the virtual lead and the optimized template to determine a strength of linear dependence between the virtual lead and the optimized template to determine regions of interest (ROIs) of the virtual lead;detecting peak correlation coefficients in the virtual lead;comparing the amplitude of each of the ROIs of the virtual lead with the selected template to determine an error between the template and each ROI of the virtual lead; andaveraging the ROIs to generate averaged data for the plurality of signals.2. The method of claim 1 , further comprising:detecting regions of poor signal quality for each of the plurality of signals; anddetermining which of the plurality of signals is associated with a bad channel based on the detected regions of poor signal ...

Methods and systems for determining physiological information based on a peak of a cross-correlation

A physiological monitoring system may process a physiological signal such a photoplethysmograph signal from a subject. The system may determine physiological information, such as a physiological rate, from the physiological signal. The system may use search techniques and qualification techniques to determine one or more initialization parameters. The initialization parameters may be used to calculate and qualify a physiological rate. The system may use signal conditioning to reduce noise in the physiological signal and to improve the determination of physiological information. The system may use qualification techniques to confirm determined physiological parameters. The system may also use autocorrelation techniques, cross-correlation techniques, fast start techniques, and/or reference waveforms when processing the physiological signal.

SYSTEMS AND METHODS FOR PROCESSING PHYSIOLOGICAL SIGNALS IN WAVELET SPACE

Methods and systems are disclosed for analyzing multiple scale bands in the scalogram of a physiological signal in order to obtain information about a physiological process. An analysis may be performed to identify multiple scale bands that are likely to contain the information sought. Each scale band may be assessed to determine a band quality, and multiple bands may be combined based on the band quality. Information about a physiological process may determined based on the combined band. In an embodiment, analyzing multiple scale bands in a scalogram arising from a wavelet transformation of a photoplethysmograph signal may yield clinically relevant information about, among other things, the blood oxygen saturation of a patient. 1. A method for processing a physiological signal of a subject , comprising:receiving, from a sensor, the physiological signal;determining, using a processor, a pulse rate of the subject based at least in part on the physiological signal;transforming, using the processor, the physiological signal into a transformed signal based at least in part on a wavelet transform;determining, using the processor, a quality associated with each of a plurality of scales of the transformed signal, wherein each of the plurality of scales is based at least in part on the pulse rate;combining, using the processor, the plurality of scales of the transformed signal to generate combined scale data based at least in part on the associated qualities; anddetermining, using the processor, physiological information of the subject based at least in part on the combined scale data.2. The method of claim 1 , wherein the plurality of scales corresponds to scales associated with the pulse rate and multiples of the pulse rate.3. The method of claim 1 , wherein the plurality of scales comprises a first scale corresponding to the pulse rate claim 1 , a second scale corresponding to two times the pulse claim 1 , and a third scale corresponding to three times the pulse rate.4. ...

CLOUD-BASED PHYSIOLOGICAL MONITORING SYSTEM

A cloud-based physiological monitoring system has a sensor in communications with a living being so as to generate a data stream generally responsive to a physiological condition of the living being. A monitor receives the data stream from the sensor and transmits the data stream to a cloud server. The cloud server processes the data stream so as to derive physiological parameters having values responsive to the physiological condition. The cloud server derives a medical index based upon a combination of the physiological parameters. The cloud server communicates the medical index to the monitor, which displays the medical index. 1. (canceled)2. A physiological monitoring system comprising: receive one or more data streams responsive to changes in one or more physiological conditions of a patient;', a first parameter of the plurality of parameters is indicative of hemoglobin (Hgb) of the patient,', 'a second parameter of the plurality of parameters is indicative of blood urea nitrogen (BUN) of the patient,', 'a third parameter of the plurality of parameters is indicative of creatinine (Cr) of the patient,', 'a fourth parameter of the plurality of parameters is indicative of a plethysmograph variability index (PVI) of the patient, and', 'a fifth parameter of the plurality of parameters is indicative of a blood pressure of the patient;, 'process the data streams so as to derive a plurality of parameters responsive to the changes in the one or more physiological conditions, wherein at least, 'determine trends in the first, second, third, fourth, and fifth parameters, the trends indicative of changes in the respective first, second, third, fourth, and fifth parameters over time; and', 'derive a medical index based upon a combination of the trends in the first, second, third, fourth, and fifth parameters, the medical index indicating a medical condition of the patient., 'one or more processors configured to execute program instructions to cause the system to3. The ...

ELECTRONIC DEVICE AND METHOD FOR PROVIDING PERSONALIZED BIOMETRIC INFORMATION BASED ON BIOMETRIC SIGNAL USING SAME

An electronic device for providing biometric information is provided. The electronic device includes a sensor module, a memory, and a processor electrically connected to the sensor module and the memory. The processor obtains a biometric signal from the sensor module at a predetermined time interval, determines whether a user is in a first state on the basis of the obtained biometric signal, in case the user is in a first state, obtains a representative value for a respective of the at least one biometric signal, defines the obtained representative value for the respective of the at least one biometric signal as a candidate reference value for a corresponding biometric signal, determines a candidate reference value satisfying a predetermined condition as a first reference value for the corresponding biometric signal, and updates a second reference value previously configured for the corresponding biometric signal on the basis of the first reference value. 1. An electronic device comprising:a sensor module;a memory; andat least one processor electrically connected to the sensor module and the memory, obtain at least one biometric signal from the sensor module at a predetermined time interval,', 'determine whether a user is in a first state on the basis of the obtained at least one biometric signal,', 'in case the user is in the first state, obtain a representative value for a respective of the at least one biometric signal,', 'define the obtained representative value for the respective of the at least one biometric signal as a candidate reference value for a corresponding biometric signal,', 'determine a candidate reference value satisfying a predetermined condition as a first reference value for the corresponding biometric signal, and', 'update a second reference value previously configured for the corresponding biometric signal on the basis of the first reference value., 'wherein the at least one processor is configured to2. The electronic device of claim 1 , ...

METHODS FOR ASSESSING SWALLOWING MOTOR FUNCTION

The present invention relates to methods for assessing swallowing motor function in a subject. The methods rely on obtaining intraluminal impedance and pressure measurements from the pharynx and/or esophagus of the subject during clearance of a bolus from the mouth and/or throat of the subject. The intraluminal impedance and pressure measurements are combined to derive a value for one or more pressure-flow variables in the pharynx and/or the esophagus of the subject. The value of the one or more pressure-flow variables is compared to a predetermined pharyngeal and/or esophageal reference value for the one or more pressure-flow variables in order to provide an assessment of swallowing motor function in the subject. The intraluminal impedance and pressure measurements can also be combined to generate a swallow risk index for the subject or to generate an obstructive risk index for the subject based on a combination of a value of more than one pressure-flow variable in the pharynx and/or esophagus of the subject. In this way, swallowing motor function in the subject can be assessed by comparing the swallow risk index or obstructive risk index for the subject to a predetermined reference swallow index or predetermined reference obstructive index, respectively. Products which make use of these methods are also encompassed by the present invention. 1. A method for assessing swallowing motor function in a subject , the method including:(a) accessing intraluminal impedance measurements and pressure measurements obtained from the pharynx, the esophagus or a combination of the pharynx and esophagus of the subject during clearance of a bolus from the mouth, the throat or a combination of the mouth and the throat of the subject; (i) using the intraluminal impedance measurements to generate an impedance waveform during clearance of the bolus, and using the pressure measurements to generate a pressure waveform during clearance of the bolus; and', '(ii) using the intraluminal ...

Biometric assessment in fitness improvement

In some embodiments, an automated system comprises one or more biometric sensors, an interactive screen, and an exercise routine generation application communicable with a mobile application. In some embodiments, the mobile application receives data from an automated station and displays exercise routines, other exercise information, or both. In some embodiments, the mobile application includes a scanner to scan labels, other indicia, or physical or other features of an exercise machine or other exercise apparatus to identify the machine or apparatus. In some embodiments, the mobile application communicates with one or more local or remote databases identifying differing exercise facility locations within a geographic area and identifying exercise apparatus available in each of the differing facilities.

Image Processing Device, Method and Non-Transitory Storage Medium

At least one of the common regions in time-sequence images is specified. Then, the time-sequence images are adjusted such that the position of that common region in at least one image among the time-sequence images is adjusted to the position of that common region in a different image. Then, the new adjusted time-sequence images are subjected to video compression processing. 1. An image processing apparatus comprising:a time-series image acquirer configured to acquire time-series images made up of a plurality of raw images generated in a time series;a common region designator configured to designate at least one common region that is commonly included in the time-series images acquired by the time-series image acquirer;a positioning processor configured to adjust the time-series images by bringing a common region that is represented by at least one raw image of the time-series images into positional alignment with a common region that is represented by another raw image; andan image compression processor configured to perform a moving-image compression process on new time-series images adjusted by the positioning processor.2. The image processing apparatus according to claim 1 , wherein the time-series image acquirer acquires claim 1 , as the time-series images claim 1 , a time series of cross-sectional image groups generated by capturing slice images along an axial direction; andthe positioning processor adjusts the time-series images by positioning the common region along the axial direction.3. The image processing apparatus according to claim 2 , wherein the positioning processor adjusts the time-series images by using a position of the common region claim 2 , which is represented by one raw image of the time-series images as a reference claim 2 , and bringing the common regions that are represented by remaining raw images into positional alignment with the reference.4. The image processing apparatus according to claim 2 , wherein the positioning processor ...

METHOD FOR DETERMINING A PERSON'S SLEEPING PHASE WHICH IS FAVOURABLE FOR WAKING UP

A pulse wave signal is registered and an occurrence of human limb movements detected during sleep using a pulse wave sensor and an accelerometer. The values of RR intervals and respiratory rate are measured at preset time intervals Δtbased on pulse wave signal. Mean P, minimal P, and maximal Pvalues of RR intervals, the standard deviation of RR intervals P, average respiratory rate Pand average number of limb movements Pare determined based on the above measured values. Function value F(Δt) is determined thereafter as: 2. The method of claim 1 , comprising selecting a time interval over which a value of parameter Pis measured in a range from 4 minutes to 6 minutes.3. The method of claim 1 , comprising selecting a time interval over which parameter value Pis measured in a range from 4 minutes to 6 minutes.4. The method of claim 1 , wherein the value of weight coefficient Kfor parameter P claim 1 , measured in ms claim 1 , is selected in the range from 0.6 msto 3 ms; the value of weight coefficient Kfor parameter P claim 1 , measured in ms claim 1 , is selected in the range of 0.1 msto 0.7 ms; the value of weight coefficient Kfor parameter P claim 1 , measured in ms claim 1 , is selected in the range of from 0.01 msto 0.3 ms; the value of weight coefficient Kfor parameter P claim 1 , measured in ms claim 1 , is selected in the range from 0.5 msto 3 ms; the value of weight coefficient Kfor parameter P claim 1 , measured in min claim 1 , is selected in the range from 1 min to 10 min; and the value of weight coefficient Kfor parameter Pis selected in the range from 5 to 50.5. The method of claim 4 , comprising selecting the value of the weight coefficient Kin a range from 0.9 msto 1.05 ms.6. The method of claim 4 , comprising selecting the value of the weight coefficient Kin a range from 0.1 msto 0.2 ms.7. The method of claim 4 , comprising selecting the value of the weight coefficient Kin a range from 0.02 msto 0.05 ms.8. The method of claim 4 , comprising selecting the ...

METHOD AND APPARATUS FOR MEASUREMENT OF CARDIOPULMONARY FUNCTION

A method for measuring anatomical dead space in a lung, the method comprising: 148-. (canceled)49. A method for adjusting ventilator settings in a ventilated patient based on information obtained by measuring anatomical dead space Vin a lung , the method comprising:delivering, through a breathing tube a supply of inspired gas, to the ventilated patient for inhalation; injecting, by a flow control means, the indicator gas into the supply of inspired gas via the breathing tube;', 'processing, by a processing unit, a measured flow rate and concentration of the inspired indicator gas over each breath so as to determine, from breath to breath, an injection rate for the inspired indicator gas that will cause the inspired indicator gas to follow the sinewave pattern, and', 'injecting the indicator gas, by the flow control means, at the determined injecting rate caused by a feedback control from a gas mixing controller to the flow control means, the feedback control based on the measured flow rate, concentration of the inspired indicator gas, the injection rate from the mass flow controller, the supply of the inspired gas, and feedback from a flow sensor and a gas analyzer each in communication with the breathing tube;, 'controlling concentration of an indicator gas for inhalation by a mass flow controller to follow a sinewave pattern over successive breaths, bymeasuring, by the flow sensor and the gas analyzer, the flow rate and concentration of the indicator gas during inspiration and exhalation of the patient;{'sub': I', 'Ē', 'E, 'fitting sinewave envelopes to the measured concentration of the indicator gas over the successive breaths and, from the fitted sinewave envelopes, determining, by the system controller, the inspired concentration F, the mixed expired concentration F, and the end expired concentration Fwith respect to the indicator gas for each breath; and'} [{'sub': T', 'T, 'calculating a tidal volume Vby integrating over time, from the start of a respective ...

Apparatus and method for estimating bio-information

Provided is an apparatus for non-invasively estimating bio-information by analyzing a pulse waveform. The apparatus for estimating bio-information according to an aspect of the present disclosure includes a processor configured to obtain a first characteristic point from a first pulse wave signal measured by a pulse wave sensor at a calibration time, obtain a second characteristic point from a second pulse wave signal measured by the pulse wave sensor at a bio-information estimation time, based on time information of the obtained first characteristic point, and estimate the bio-information of an object based on the obtained second characteristic point.

Combined Optical Sensor for Audio and Pulse Oximetry System and Method

A system includes at least one earpiece, wherein each earpiece comprises an earpiece housing, an optical source operatively connected to the earpiece housing, wherein the optical source is configured to emit light toward an ear surface, an optical sensor operatively connected to the earpiece housing, wherein the optical sensor is configured to receive reflected light from the ear surface, and at least one processor disposed within at least one earpiece and operatively connected to the optical source and the optical sensor, wherein the at least one processor is configured to separate the pulse oximetry signals from the audio signals in the reflected light detected by the optical sensor. 1. A system comprising:at least one earpiece, wherein each earpiece comprises an earpiece housing;an optical source operatively connected to the earpiece housing, wherein the optical source is configured to emit light toward an ear surface;an optical sensor operatively connected to the earpiece housing, wherein the optical sensor is configured to receive reflected light from the ear surface; andat least one processor disposed within at least one earpiece and operatively connected to the optical source and the optical sensor, wherein the at least one processor is configured to separate the pulse oximetry signals from the audio signals in the reflected light detected by the optical sensor.2. The system of wherein the at least one processor is further configured to determine an oxygen saturation level from the pulse oximetry signals.3. The system of wherein the at least one processor applies a filter to separate the pulse oximetry signals from the audio signals claim 1 , the audio signals centered at frequency higher than the pulse oximetry signals.4. The system of wherein the at least one earpiece comprises a set of earpieces.5. The system of wherein the optical source is a laser.6. The system of wherein the ear surface comprises an outer ear surface.7. The system of wherein the ear ...

Non-Contact Assessment of Cardiovascular Function using a Multi-Camera Array

A method is provided for non-contact cardiac assessment of a subject. Images of the subject are captured from at least two synchronized independent imaging devices spaced equidistant from the subject and positioned such that each imaging device captures an image of the subject different from other imaging devices. Spectral components of the captured images are extracted. The extracted spectral components are analyzed. A signal corresponding to cardiac information is identified in the extracted spectral components. The identified signal corresponding to the cardiac information is extracted from the extracted spectral components. 1. A method for non-contact cardiac assessment of a subject , the method comprising:capturing images of the subject from at least two synchronized independent imaging devices spaced equidistant from the subject and positioned such that each imaging device captures an image of the subject different from other imaging devices;extracting spectral components of the captured images;analyzing the extracted spectral components;identifying a signal in the extracted spectral components corresponding to cardiac information; andextracting the signal in the extracted spectral components corresponding to the cardiac information.2. The method of claim 1 , wherein capturing the images of the subject from at least two synchronized independent imaging devices comprises:capturing images of a head and neck of the subject from the at least two synchronized independent imaging devices.3. The method of claim 1 , wherein extracting spectral components of the captured images comprises:extracting Red, Green, and Blue components of the captured images.4. The method of claim 1 , wherein analyzing the extracted spectral components comprises:performing an independent component analysis on the extracted spectral components.5. The method of claim 1 , wherein identifying a signal in the extracted spectral components corresponding to cardiac information comprises:bandpass ...

A NON-INVASIVE SENSING SYSTEM

A non-invasive sensing system for measuring the concentration of a substance within an object, the system including a support element adapted to be placed near to, or against, a surface of the object, a first transmitting antenna mounted upon or within the support element for transmitting electromagnetic radiation signals into the object, and a second receiving antenna mounted upon or within the support element, and adjacent to the first transmitting antenna, for receiving at least a portion of the electromagnetic radiation signals that are reflected back to the same surface of the object covered by the support element, due to the transmitted electromagnetic radiation signals having interacted with the substance within the object being measured. 1. A non-invasive sensing system for measuring the concentration of a substance within an object , said system comprising:a. a support means adapted to be placed near to, or against, a surface of the object,b. a first transmitting antenna mounted upon or within the support means for transmitting electromagnetic radiation signals into the object, andc. a second receiving antenna mounted upon or within the support means, and adjacent to the first transmitting antenna, for receiving at least a portion of the electromagnetic radiation signals that are reflected back to the same surface of the object covered by the support means, due to the transmitted electromagnetic radiation signals having interacted with the substance within the object being measured.2. The non-invasive sensing system for measuring the concentration of a substance within an object claim 1 , as claimed in claim 1 , wherein the system further includes an analyser which is in electrical communication with the first transmitting antenna and the second receiving antenna claim 1 , the analyser being adapted to break down the reflected signal received by the second receiving antenna into spectra or a spectral file.3. The non-invasive sensing system for measuring the ...

Method and a system for detecting a vital sign of a subject

A method for detecting a vital sign of a subject (102) comprises: receiving (302) a reflected radio frequency signal from the subject (102), the reflected signal being based on a transmitted signal, which is Doppler-shifted due to mechanical movements corresponding to the heart rate and/or the respiratory rate; dividing (304) a baseband signal into a sequence of sliding windows (200), each sliding window (200) representing a time interval; estimating (306) a vital sign parameter in at least one sliding window (200); determining (308) whether a vital sign parameter may be reliably estimated in at least one sliding window (200); on condition that the vital sign parameter may not be reliably estimated in a sliding window (200), determining (310) a vital sign parameter of the sliding window (200) based on vital sign parameters estimated in a plurality of windows representing time intervals close to the time interval of the window (200).

Physiological Metric Estimation Rise and Fall Limiting

Methods and apparatus disclosed herein use a filtering technique to improve the accuracy of the results achieved when processing data provided by a physiological sensor. The disclosed filtering technique corrects many of the accuracy problems associated with physiological sensors, particularly PPG sensors. Broadly, the filtering technique adjusts a current filtered estimate of a physiological metric as a function of a rate limit based on a comparison between an instantaneous estimate of the physiological metric and the current filtered estimate. 1. A physiological processor configured to process a waveform provided by a photoplethysmography sensor , the processor comprising:a spectral transformer configured to determine, based on the waveform, an instantaneous estimate of a heart rate; and compare the instantaneous estimate to a current filtered estimate of the heart rate; and', 'output a revised filtered estimate of the heart rate computed as a function of the current filtered estimate and a rate limit based on the comparison between the instantaneous estimate and the current filtered estimate., 'a filter configured to2. A method of processing data provided by a physiological sensor , the method comprising:receiving a physiological waveform from the physiological sensor;determining, based on the physiological waveform, an instantaneous estimate of a physiological metric;comparing the instantaneous estimate to a current filtered estimate of the physiological metric;computing a revised filtered estimate of the physiological metric as a function of the current filtered estimate and a rate limit based on the comparison between the instantaneous estimate and the current filtered estimate; andoutputting the revised filtered estimate.3. The method of further comprising computing an adjustment parameter as a function of the current filtered estimate claim 2 , the instantaneous estimate claim 2 , and the rate limit based on the comparison between the instantaneous estimate ...

System and Method for Determining Bilirubin Levels in Newborn Babies

The present invention provides a system and method for determining bilirubin levels in an individual based on skin coloration using a smartphone or other personal device and an attached ancillary apparatus. The device, such as a smartphone or tablet, is capable of storing and running software. The device is also coupled to both a camera and light source to obtain data regarding the skin's coloration. Software is installed on the device to control the light source and calculate bilirubin levels in the individual based on the input received from the camera. The ancillary apparatus is a mechanism surrounding the light source and camera that is placed on the skin of the individual when the system is in use. The ancillary apparatus thus creates a light tight seal between the skin, light source and camera, enabling the system to receive the most accurate data from the camera. 1. A system for monitoring the levels of at least one substance in skin based on the substance's optical properties , comprising: a memory;', 'a processor;', 'a camera coupled to said processor;', 'a light source coupled to said processor; and', 'a software module stored in the memory, said software module configured to run on said processor configured to control the light emitted by the light source, control the camera, and analyze at least one measurement of an amount of light from the camera to calculate concentrations of the at least one substance using an algorithm; and, 'a device includingan ancillary module coupled to said device such that when placed on the skin creates a light-tight housing for the camera of said device.2. A system as claimed in wherein the device is a mobile device.3. A system as claimed in wherein the mobile device is a smartphone.4. A system as claimed in in where the mobile device is a tablet or computer.5. A system as claimed in wherein the ancillary module includes a sensor for measuring whether a light-tight seal has been created between said camera and the skin.6. A ...

Automated methods and systems for vascular plaque detection and analysis

Automated methods and systems for the detection and analysis of plaque in one or more regions of a patient's vasculature are described.

HEART SOUND DENOISING APPARATUS, METHOD, AND PROGRAM

Provided is a heart sound denoising apparatus that includes: a heart sound signal acquisition unit that acquires a heart sound signal collected by a sound collector; a pulsation signal acquisition unit that acquires a pulsation signal of a living body; a peak interval acquisition unit that acquires a peak interval of the acquired pulsation signal; a first resampling unit that resamples the heart sound signal corresponding to the acquired peak interval, to a predetermined number of samples, with respect to the heart sound signal detected at a same time as the acquired pulsation signal; a noise removal unit that removes a noise component from the resampled heart sound signal; and a second resampling unit that resamples the heart sound signal resampled by the first resampling unit and with the noise removed, to a number of samples of the peak interval. 1. A heart sound denoising apparatus comprising:a heart sound signal acquisition unit that acquires a heart sound signal collected by a sound collector;a pulsation signal acquisition unit that acquires a pulsation signal of a living body;a peak interval acquisition unit that acquires a peak interval of the acquired pulsation signal;a first resampling unit that resamples the heart sound signal corresponding to the acquired peak interval, to a predetermined number of samples, with respect to the heart sound signal detected at a same time as the acquired pulsation signal;a noise removal unit that removes a noise component from the resampled heart sound signal; anda second resampling unit that resamples the heart sound signal resampled by the first resampling unit and with the noise removed, to a number of samples of the peak interval.2. The heart sound denoising apparatus according to claim 1 , wherein the pulsation signal is an electrocardiac signal indicating an electrical change associated with a pulsation claim 1 , or a pulse wave signal indicating a change in a flow of blood associated with the pulsation.3. The heart ...

EMBEDDING VISUAL INFORMATION INTO ECG SIGNAL IN REAL TIME

Embodiments include methods, systems, and apparatuses for generating an enhanced electrocardiograph (ECG) that includes indicators of values of different types of supplemental information embedded into a trace of measured electrical potentials. More specifically, embodiments may include collecting first data samples of electrical potentials produced by a heart at a sequence of sampling times, and processing the data to calculate supplemental information over a number of sampling times. Based on the first data samples and the supplemental information, a trace of the electrical potentials collected at the sampling times is presented. The trace may have one or more embedded indicators of the supplemental information that vary responsively to the first data samples collected at each of the sampling times. 1. A method comprising:collecting first data samples of electrical potentials produced by a heart at a sequence of sampling times, wherein the first data samples are collected by one or more electrodes;generating supplemental information based on at least the differences in the first data samples gathered over a number of the sampling times;generating, based on the first data samples, a trace of the electrical potentials collected at the sampling times, wherein the trace comprises a line chart; andembedding one or more indicators in the line chart based on the supplemental information, wherein the one or more indicators vary responsively to the first data samples collected at each of the sampling times.2. The method of claim 1 , wherein the one or more electrodes are located on a distal end of a probe inserted into the heart.3. The method of claim 1 , wherein the one or more electrodes are external to the heart.4. The method of claim 1 , further comprising:collecting second data samples with respect to the heart at the sampling times; anddisplaying the second data samples as the one or more embedded indicators.5. The method of claim 4 , wherein the second data samples ...

System and Method for Monitoring Respiratory Rate and Oxygen Saturation

A method and system for monitoring respiratory rate of a patient is provided. An example system includes a wearable device configured to be disposed around a wrist of the patient. The wearable device may include a gyroscope to measure a gyroscope signal indicative of a motion of the patient. The system may further include a processor communicatively coupled to the gyroscope. The processor can be configured to perform a spectral analysis of the gyroscope signal to obtain a spectrum in a pre-determined range. The pre-determined range may cover a normal respiratory rate range. The processor can be further configured to determine a position of a peak in the spectrum to obtain a value for the respiratory rate. The processor can be further configured to provide, based on the value of the respiratory rate, a message regarding a health status of the patient.

Apparatus and method for obtaining bio-information

An apparatus for obtaining bio-information may include a pulse wave sensor including a light source and a detector. The light source is configured to emit multi-wavelength light to an object of interest and the detector is configured to detect light reflected from the object. In addition, the apparatus may include a processor configured to obtain a change in volume of a blood vessel based on one or more of quantity of detected multi-wavelength light and absorbance coefficients of respective wavelengths of the multi-wavelength light and obtain bio-information based on the measured change in volume of the blood vessel.

SYSTEM AND METHOD FOR PHYSIOLOGICAL PARAMETER MONITORING

A device, method and system for calculating, estimating, or monitoring the blood pressure of a subject. A first signal representing heart activity of a subject may be received. A plurality of second signals representing time-varying information on at least one pulse wave of the subject may be received from a plurality of body locations of the subject. A first feature of the first signal may be identified. For each of the plurality of second signals, a second feature may be identified. A pulse transit time based on a difference of the first feature and at least one of the second features may be computed. A blood pressure of the subject may be calculated according to a model based on the computed pulse transit time. The model may include a compensation term relating to the plurality of second signals or the second features thereof. 1. A system , comprising:at least one storage device storing instructions; andat least one processor in communication with the at least one storage device, where when executing the instructions, the at least one processor is directed to perform operations comprising:receiving a first signal representing heart activity of a subject;receiving a plurality of second signals representing time-varying information on at least one pulse wave of the subject, the plurality of second signals corresponding to a plurality of body locations of the subject respectively;determining a plurality of pulse transit times (PTTs) based on the plurality of second signals and the first signal;determining a plurality of blood pressures of the subject based on the plurality of PTTs respectively, the plurality of blood pressures corresponding to the plurality of body locations respectively;determining relation information among the plurality of blood pressures;generating guide information associated with the subject based on the relation information; andtransmitting the guide information to a terminal device associated with the subject.2. The system of claim 1 , ...

Portable hydration monitoring device and methods

A method operable to monitor hydration including pressing a finger of a user against a finger cradle of a device, creating a finger press; sensing, via at least one sensor, a finger presence; providing an alarm indicating a pressure to apply; emitting, via at least one electromagnetic emitter, radiation through the finger; detecting, via at least one electromagnetic detector, radiation through the finger; verifying, via a synchronization line, that the electromagnetic radiation is applied synchronously with one or more finger presses; converting, via at least one analog-to-digital converter, the radiation detected by the electromagnetic detector into digital information; and converting, via a processing unit, the finger pressure data and the detected electromagnetic radiation data into a hydration level using an algorithm stored on the processing unit; and conveying the hydration level to at least one alarm unit coupled with the device.

Apparatus and Method for Measuring Physiological Signals

A measuring unit has at least one first signal-measuring end and at least one second signal-measuring end. The first signal-measuring end and the second signal-measuring end contact at least two symmetrical portions of a living being to obtain at least one first pulse signal and at least one second pulse signal of the two symmetrical portions, respectively. A signal-analyzing unit is coupled to the measuring unit. The signal-analyzing unit obtains at least one physiological data based on the first pulse signal and the second pulse signal, respectively, further to determine a physiological condition of the living being according to the physiological data. 1. An apparatus for measuring a physiological signal , comprising:a measuring unit having at least one first signal-measuring end and at least one second signal-measuring end, the first signal-measuring end and the second signal-measuring end contacting at least two symmetrical portions of a living being to obtain at least one first pulse signal and at least one second pulse signal of the two symmetrical portions, respectively; anda signal-analyzing unit coupled to the measuring unit, the signal-analyzing unit obtaining at least one physiological data based on the first pulse signal and the second pulse signal, respectively, further to determine a physiological condition of the living being according to the physiological data.2. The apparatus for measuring a physiological signal according to claim 1 , wherein the physiological data comprises at least one first physiological data group and at least one second physiological data group.3. The apparatus for measuring a physiological signal according to claim 2 , wherein the first physiological data group comprises at least one first crest-to-cycle ratio and at least one second crest-to-cycle ratio.4. The apparatus for measuring a physiological signal according to claim 2 , wherein the measuring unit further comprises a third signal-measuring end for measuring an ECG ...

MEASUREMENT OF PHYSIOLOGICAL CHARACTERISTICS

A system for measuring physiological aspects has a non-invasive monitor configured to generate monitor signals relating to fluid characteristics in the head and body. A computational device is operatively connected to the monitor and is configured to process the monitor signals to generate characterizing data relating to at least one of regional fluid volumes, intra/extracellular fluid volume ratios and blood flow. A data output device is connected to the computational device and is configured to output the characterizing data. A method and a computer program product for recording, measuring, and displaying physiological characteristics are also provided. 1. A system for measuring physiological aspects , the system comprising:a. a non-invasive monitor consisting of and configured to capture impedance data on at least three different frequencies;b. a computational device operatively connected to the monitor and configured to process the impedance data to generate characterizing data relating to at least one of regional fluid volumes, intra/extracellular fluid volume ratios and blood flow; andc. a data output device connected to the computational device and configured to output the characterizing data.2. The system as claimed in claim 1 , which includes at least one excitation electrode for providing an electrical stimulus across selected head or body areas.3. The system as claimed in claim 1 , in which the monitor comprises a number of electrodes that are configured to be placed in a non-invasive manner into operative engagement with the head claim 1 , body or the head or body claim 1 , such that at least one electrode engages each of a number of respective segments of the head and the body.4. The system as claimed in claim 1 , in which the monitor is configured to record steady state resistance on each frequency as well as pulsing wave resistance on at least three different frequencies.5. The system as claimed in claim 1 , in which the monitor is configured to use ...

PROCESSOR DEVICE AND METHOD FOR OPERATING SAME, AND ENDOSCOPIC SYSTEM AND METHOD FOR OPERATING SAME

An image signal acquisition unit acquires a first image signal corresponding to a first wavelength band, a second image signal corresponding to a second wavelength band, a third image signal corresponding to a third wavelength band, and a fourth image signal corresponding to a fourth wavelength band. A correlation storage unit stores a correlation between oxygen saturation degree and a first calculated value obtained from a specific calculation based on the second image signal, the third image signal, and the fourth image signal. A correlation correction unit calculates a correlation correction amount on the basis of the first image signal, the second image signal, the third image signal, and the fourth image signal, and corrects the correlation on the basis of the correction amount. 1. A processor device comprising:an image signal acquisition unit that acquires a first image signal corresponding to a first wavelength band whose light absorption amount varies according to a density of a pigment other than hemoglobin among pigments included in an observation target, a second image signal corresponding to a second wavelength band whose light absorption amount varies according to an oxygen saturation degree of the hemoglobin included in the observation target, a third image signal corresponding to a third wavelength band that has a wavelength longer than the first wavelength band and the second wavelength band and whose light absorption amount varies according to an amount of blood, and a fourth image signal corresponding to a fourth wavelength band that has a wavelength longer than the third wavelength band;a correlation storage unit that stores a correlation between a first calculated value obtained by a specific calculation based on the second image signal, the third image signal, and the fourth image signal, and the oxygen saturation degree; anda correlation correction unit that calculates a correction amount of the correlation on the basis of the first image ...

INTRAVENOUS ACCESS DEVICE DETECTING INTRAVENOUS INFILTRATION AND IN-VEIN PLACEMENT

Aspects of the invention relates to systems and methods for monitoring an intravenous (IV) line functionality of an IV device. In one embodiment, the system includes an IV catheter to be inserted into the vein of the living subject, at least one pressure sensor in fluid communication with the IV catheter to acquire peripheral venous signals; and a processing device. The processing device receives the peripheral venous signals from the pressure sensor, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum, and then performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an IV line functionality of the IV catheter in real time. When the IV line functionality indicates IV infiltration, the processing device may control the fluid controlling device to stop the fluid flow from the fluid source to the IV catheter. 1. An intravenous (IV) system , comprising:an IV catheter, configured to be inserted into a vein of a living subject;a fluid controlling device in fluid communication with the IV catheter, configured to control fluid flow from a fluid source to the IV catheter;at least one pressure sensor in fluid communication with the IV catheter, configured to acquire, from the vein of the living subject, peripheral venous signals; and receive the peripheral venous signals from the at least one pressure sensor;', 'perform a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum;', 'perform a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an IV line functionality of the IV catheter in real time, wherein the IV line functionality of the IV catheter indicates IV infiltration when amplitude decreases greater than a first threshold are detected from the peaks of the peripheral venous pressure frequency spectrum; and', 'when the IV line ...

INTRINSIC FREQUENCY ANALYSIS FOR LEFT VENTRICLE EJECTION FRACTION OR STROKE VOLUME DETERMINATION

Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination. 111-. (canceled)12. A system for acquiring and analyzing a hemodynamic waveform , the system comprising:a light source to illuminate an area on a patient's skin;an optical sensor to determine a skin motion waveform at the area of the patient's skin illuminated by the light source; anda processor programmed to determine first and second intrinsic frequencies (IF) based on the measured skin motion waveform and to output a signal corresponding to at least one of left ventricle ejection fraction (LVEF) and stroke volume (SV) based on the determined first and second intrinsic frequencies.13. The system of claim 12 , wherein the first and second intrinsic frequencies are determined using a pre-determined ejection fraction echo versus ejection fraction intrinsic frequency relationship.14. The system of claim 12 , wherein the LVEF is calculated as a function of p claim 12 , p claim 12 , p claim 12 , Tand heart rate claim 12 , wherein p claim 12 , p claim 12 , pare minimum claim 12 , maximum claim 12 , and mean systolic pressures claim 12 , respectively claim 12 , and Tis an ejection time of the left ventricle.15. The system of claim 12 , wherein SV is calculated as a function of p claim 12 , p claim 12 , p claim 12 , Tand heart rate claim 12 , wherein p claim 12 , p claim 12 , pare minimum claim 12 , maximum claim 12 , and mean systolic pressures claim 12 , respectively claim 12 , and Tis an ejection time of the left ventricle.16. The system of claim 12 , wherein the light source is a smartphone light.17. The system of claim 12 , wherein the optical sensor is a ...

INDICATION OF RISK FOR CORONARY ARTERY DISEASE

A way of indicating a risk for coronary artery disease is disclosed. A first plurality of first sound recordings of heartbeats and second plurality of second sound recording of the ambient background are obtained. A filtering of each first sound recording is performed by using a simultaneously recorded second sound recording. The filtering of each first sound recording involves determining a diastolic period of the heartbeat of the first sound recording, and performing an adaptive filtering of the first sound recording based in the diastolic period of the first sound recording and the simultaneously recorded second sound recording. This is followed by determination of an indication of the risk for coronary artery disease based on the filtered first sound recordings. 1. A method for indicating a risk for coronary artery disease for a person , the method comprising;(a) obtaining a first plurality of first sound recordings, wherein each first recording is of a heartbeat of the person,(b) obtaining a second plurality of second sound recording, wherein each second sound recording is of an ambient background surrounding the person and being recorded simultaneously to a first sound recording of the first plurality,(c) performing a filtering of each first sound recording of the first plurality by using a simultaneously recorded second sound recording of the second plurality, the filtering of each first sound recording comprises:(i) determining a diastolic period of the heartbeat of the first sound recording, and(ii) determining a first portion of the first sound recording and a second portion of the simultaneously recorded second sound recording, wherein the first portion and the second portion are covered by the diastolic period,(iii) determining an adaptive filter for the first sound recording, wherein the adaptive filter is based on the first portion and the second portion and configured for reducing noise originating from the ambient background that is present in both ...

METHOD AND SYSTEM FOR EVALUATION OF FUNCTIONAL CARDIAC ELECTROPHYSIOLOGY

An organ evaluation device, system, or method is configured to receive electrophysiological data from a patient or model organism and integrates the data in a computational backend environment with anatomical data input from an external source, spanning a plurality of file formats, where the input parameters are combined to visualize and output current density and/or current flow activity having ampere-based units displayed in the spatial context of heart or other organ anatomy. 121.-. (canceled)22. A method of treating an individual with a cardiac arrhythmia , said method comprising:(a) generating a current density map of a heart of the individual comprising at least one current vector expressed in Ampere units or equivalent units of current measurement;(b) identifying a region of the current density map associated with the cardiac arrhythmia; and(c) ablating the region.23. The method of claim 22 , wherein the current density map is non-invasively generated.24. The method of claim 23 , wherein the current density map is based on at least one electromagnetic field data associated with the individual.25. The method of claim 22 , wherein the current vector is overlaid onto the current density map.26. The method of claim 22 , wherein the cardiac arrhythmia comprises atrial fibrillation.27. The method of claim 22 , wherein the current density map comprises a three dimensional image.28. The method of claim 22 , wherein the current density map comprises a plurality of distributed claim 22 , spatially accurate electrical current values having dynamic claim 22 , real time parameters.29. The method of claim 28 , wherein each of the plurality of electrical current values are in units of amperes or equivalent units of current measurement.30. The method of claim 22 , wherein the current density map comprises a radiographic image.31. The method of claim 30 , wherein the image comprises a two dimensional x-ray image.32. The method of claim 30 , wherein the image comprises a CT ...

INFORMATION PROCESSING APPARATUS

An information processing apparatus includes a display control unit. The display control unit is configured to execute control to display a plurality of partial waveform data in parallel in a time axis direction of the plurality of partial waveform data, the plurality of partial waveform data each representing temporal change of one or more biological signals and each respectively representing biological waveform data corresponding to a respective partial time period, spots from among the biological waveform data being specifiable, the display control unit being further configured to execute control to display the spots of the plurality of partial waveform data, with emphasis, upon being specified. 1. An information processing apparatus comprising:a display control unit configured to execute control to display a plurality of partial waveform data in parallel in a time axis direction of the plurality of partial waveform data, the plurality of partial waveform data each representing temporal change of one or more biological signals and each respectively representing biological waveform data corresponding to a respective partial time period, spots from among the biological waveform data being specifiable, the display control unit being further configured to execute control to display the spots of the plurality of partial waveform data, with emphasis, upon being specified.2. The information processing apparatus according to claim 1 , wherein the control to display with emphasis is executed to display a line extending in a direction intersecting a measurement time direction of a waveform representing the biological waveform data.3. The information processing apparatus according to claim 1 , whereinthe one or more biological signals are biological signals acquired by a plurality of measurement methods, andthe display control unit is configured to execute control to display at least one or more of the one or more biological signals acquired by the plurality of measurement ...

Ultrasonic imaging apparatus and control method thereof

Disclosed herein are an ultrasonic imaging apparatus which is capable of accurately and quickly estimating a Point Spread Function (PSF) is usable for restoring ultrasonic images, and a control method which is executable by the ultrasonic imaging apparatus. The ultrasonic imaging apparatus includes: a probe; a receive beamformer configured to beamform an ultrasonic signal and to output the beamformed ultrasonic signal; a Point Spread Function (PSF) database configured to store a PSF which is acquired based on a situational variable, and a phase parameter which is determined based on the situational variable, for the beamformed ultrasonic signal; and an image generator configured to select the PSF and the phase parameter from the PSF database based on the beamformed ultrasonic signal, and to perform deconvolution using an estimated PSF based on the selected PSF and the selected phase parameter in order to generate an image.

HEART RATE DETERMINATION BASED ON VAD CURRENT WAVEFORM

The present disclosure provides for methods and systems for determining heart rate of a patient. Based on motor current signals of a ventricular assist device (VAD), each of first, second and third events in the measured current signal may be detected, the first event being indicative of a rise or fall in the current signal, the second event being indicative of a rise or fall in the current signal in the opposite direction as the first event, and the third event being indicative of a rise or fall in the current signal in the same direction as the first event. A timer counter may be initiated upon detection of the first event, and an elapsed time may be measured upon detection of the third event. Heart rate may be determined based on the elapsed time of the timer counter. 1. A method of determining heart rate of a patient having an implantable blood pump , comprising:measuring a motor current signal of the implantable blood pump, the implantable blood pump being in fluid communication with a ventricle of the patient's heart;detecting a first event in the measured current signal, the first event being indicative of one from the group consisting of a rise in the current signal and a fall in the current signal;initiating a timer counter when detecting the first event;detecting a second event in the measured current signal, the second event being indicative of one from the group consisting of a rise in the current signal and a fall in the current signal in the opposite direction as the first event;detecting a third event in the measured current signal, the third event being indicative of one from the group consisting of a rise in the current signal and a fall in the current signal in the same direction as the first event;measuring an elapsed time of the timer counter when detecting the third event; anddetermining the heart rate of the patient based on the elapsed time of the timer counter.2. The method of claim 1 , wherein detecting the second event is initiated after ...

COMPUTERIZED METHOD AND DEVICE FOR ANALYZING PHYSIOLOGICAL SIGNAL

A computerized method and device for analyzing a physiological signal are provided. The computerized method for analyzing the physiological signal includes the following steps. A pulse waveform is measured by a measuring unit, wherein the pulse waveform represents a blood volume of a blood vessel over time. A plurality of rising segments of the plus waveform is analyzed by a processing unit. The maximum change rate point at each rising segment is analyzed by the processing unit. A pulse interval time sequence is obtained according to the maximum change rate points. 1. A computerized method for analyzing a physiological signal , comprising:measuring a pulse waveform by a measuring unit, wherein the pulse waveform represents a blood volume of a blood vessel over time;analyzing a plurality of rising segments of the pulse waveform by a processing unit;analyzing a maximum change rate point at each rising segment by the processing unit; andobtaining a pulse interval time sequence according to the maximum change rate points.2. The computerized method for analyzing the physiological signal according to claim 1 , further comprising:filtering a high frequency noise, a low frequency noise or a noise ranging within a certain frequency band of the pulse waveform by a filter.3. The computerized method for analyzing the physiological signal according to claim 1 , wherein the pulse waveform represents characteristics of the light after passing through the blood vessel over time.4. The computerized method for analyzing the physiological signal according to claim 1 , wherein step of measuring the pulse waveform comprises:providing an emitted light, wherein the emitted light is ejected to a user's finger;receiving a reflective light, wherein the reflective light is reflected from the user's finger; andrecording the value of the characteristics of the reflective light over time.5. The computerized method for analyzing the physiological signal according to claim 1 , wherein step of ...

METHOD, APPARATUS, AND SYSTEM FOR DIAGNOSING PERICARDIAL TAMPONADE

The disclosure is directed to a method, apparatus, and system for diagnosing pericardial tamponade. Pulse oximetry is a noninvasive method for monitoring a person's oxygen saturation. The method includes analyzing a pulse oximetry waveform of a person and obtaining an oximetry paradoxus corresponding to the variation of the pulse oximetry waveform, which includes identifying a maximum amplitude and a minimum amplitude of the pulse oximetry waveform within a respiratory cycle and calculating a ratio of the maximum amplitude and the minimum amplitude to obtain the oximetry paradoxus. The method also includes determining whether the oximetry paradoxus is equal to or larger than a threshold. When the oximetry paradoxus is determined to be equal to or larger than the threshold, the method identifies the person having pericardial tamponade. Therefore, the disclosure provides a noninvasive, inexpensive, and ubiquitous tool in aiding in the accurate diagnosis of pericardial tamponade. 1. A method for diagnosing pericardial tamponade , comprising: identifying, by the device, a maximum amplitude and a minimum amplitude of the pulse oximetry waveform within a respiratory cycle, and', 'calculating, by the device, a ratio of the maximum amplitude and the minimum amplitude within the respiratory cycle to obtain the oximetry paradoxus;, 'analyzing, by a device comprising a memory and a processor in communication with the memory, a pulse oximetry waveform of a person to obtain an oximetry paradoxus, wherein the analyzing the pulse oximetry waveform to obtain the oximetry paradoxus comprisesdetermining, by the device, whether the oximetry paradoxus is equal to or larger than a threshold; andwhen the oximetry paradoxus is determined to be equal to or larger than the threshold, identifying, by the device, the person as having or suspected as having pericardial tamponade.2. The method of claim 1 , whereinthe pulse oximetry waveform comprises one or more respiratory cycles.3. The method ...

Device and Method for Measuring and Displaying Bioelectrical Function of the Eyes and Brain

Apparatus, system, and computer-readable media measure electroencephalography (EEG) signals or ERG signals generated from a device that presents a series of images on a timing cycle to a subject. The apparatus comprises a Central Processing Unit (CPU), Power Supply Unit (PSU), Random Access Memory (RAM), and a hard drive (HDD). The apparatus further includes at least one electrode and a photo-sensor like a photodiode for conversion of light into electric current. The CPU is operable with software for converting the EEG or ERG signals evoked from the visual stimuli to provide data and retrieving the status of EEG signals.

METHOD AND APPARATUS FOR IMPROVING LAG CORRECTION DURING IN VIVO MEASUREMENT OF ANALYTE CONCENTRATION WITH ANALYTE CONCENTRATION VARIABILITY AND RANGE DATA

Methods, devices, and systems are provided for correcting lag in measurements of analyte concentration level in interstitial fluid. The invention includes receiving a signal representative of sensor data from an analyte monitoring system related to an analyte level measured over time, computing rates of change of the sensor data for a time period of the sensor data, computing a rate distribution of the rates of change, transforming the rate distribution into a linear arrangement, determining a best-fit line for the transformed rate distribution, computing a slope of the best-fit line; and using the slope of the best-fit line as a representation of a variability of the analyte level to adjust an amount of lag correction applied to the sensor data. Numerous additional features are disclosed. 1. A method for lag correction of sensor data from an analyte sensor , comprising:receiving sensor data from an analyte sensor, the sensor data including historical analyte sensor data over a plurality of intervals;determining a variability of the historical analyte sensor data over each of the plurality of intervals;comparing the variability of the historical analyte sensor data of a recent interval of the plurality of intervals to at least one prior variability determined from prior intervals of the plurality of intervals;setting an amount of lag correction based on at least one of the variability of the recent interval and the at least one prior variability; andcomputing lag corrected values based on the amount of lag correction.2. The method of claim 1 , further comprising:defining a probability density function of the historical analyte sensor data over at least a portion of one of the plurality of intervals; andsetting the amount of lag correction based on at least one of the variability of the recent interval, the at least one prior variability, and the probability density function of the historical analyte sensor data.3. The method of claim 1 , wherein the variability of ...

System and method for monitoring physiological activity of a subject

A system and associated method is disclosed to monitor physiological activity of a subject. One or more sensors are positioned in or on a support, the support being adapted to receive the subject, at least a first one of the sensors being adapted to produce a first signal indicative of movement of the subject over time. Processing apparatus is adapted to identify first, second and third portions of the first signal. The first and third portions correspond to first and third time periods, respectively, during which the subject changes body position on the support. The second portion corresponds to a second time period, between the first and third time periods, during which substantially no change in body position of the subject on the support takes place.

BLOOD PRESSURE RELATED INFORMATION DISPLAY APPARATUS AND PROGRAM

A blood pressure related information display apparatus acquires blood pressure data including at least early-morning blood pressure data measured in the morning and night-time blood pressure data measured at night in a certain period for the measurement subject. The blood pressure related information display apparatus sets one of early-morning blood pressure and night-time blood pressure on a horizontal axis and the other on a vertical axis and performs graph display of points determined using early-morning blood pressure data and night-time blood pressure data on the display screen. 1. A blood pressure related information display apparatus configured to display information related to blood pressure of a measurement subject on a display screen , comprising:a blood pressure data acquisition unit configured to acquire blood pressure data including at least early-morning blood pressure data measured in the morning and night-time blood pressure data measured at night in a certain period for the measurement subject; anda display control unit configured to set one of early-morning blood pressure and night-time blood pressure on a horizontal axis and the other on a vertical axis, and perform graph display of a point determined by the early-morning blood pressure data and the night-time blood pressure data on the display screen.2. The blood pressure related information display apparatus according to claim 1 , whereinthe display control unit performs graph display of a first reference line indicating a reference value for determining early-morning hypertension and a second reference line indicating a reference value for determining night-time hypertension on the display screen, and performs display of which type the point on the display screen is to be classified into among a night-time hypertension type in which hypertension occurs at night but not in the early morning, an early-morning hypertension type in which hypertension does not occur at night but does occur in the ...

System and method for determining stability of cardiac output

A PPG system includes a processor configured to receive a PPG signal from a PPG sensor, the PPG signal having a plurality of pulses each representing a heartbeat of a patient. The processor is also configured to determine an amplitude variance of the plurality of pulses over a time period, determine a pulse period variance of the PPG signal over the time period, determine a cardiac stability based on a ratio of the amplitude variance and the pulse period variance, and provide an indication of the cardiac stability via a display. The amplitude variance includes an average of squared differences of an amplitude of a peak of each pulse of the plurality of pulses from a mean amplitude of the plurality of pulses over the time period, and the mean amplitude includes an average of respective midpoints of each of the plurality of pulses over the time period.

Assessing Effectiveness of CPR

Novel tools and techniques are provided for assessing, predicting and/or effectiveness of cardiopulmonary resuscitation (“CPR”), in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid estimation of a patient's compensatory reserve index (“CRI”) before, during, and after CPR is performed, and using the CRI and variations in CRI values to determine, in some instances, in real-time, the effectiveness of CPR that is performed.

Electronic device for determining biometric information and method of operating same

An electronic device includes a first sensor, a camera, and a processor functionally connected to the first sensor and the camera, wherein the processor is configured to acquire a first biometric signal through the first sensor and a second biometric signal through the camera at a first location, acquire a third biometric signal through the first sensor and a fourth biometric signal through the camera at a second location, and determine a blood pressure based on the first biometric signal and the second biometric signal acquired at the first location and the third biometric signal and the fourth biometric signal acquired at the second location.

BLOOD PRESSURE MEASURING APPARATUS, WRIST WATCH TYPE TERMINAL HAVING THE SAME, AND METHOD OF MEASURING BLOOD PRESSURE

Provided is a blood pressure measuring apparatus, a wrist watch type terminal, and a method of measuring blood pressure. The blood pressure measuring apparatus includes a light source that emits light onto a living body, a light receiver that receives light from the living body, and a signal processing device that calculates the blood pressure based on a detected signal received from the light receiver, wherein the signal processing device includes a subtractor that obtains a subtraction value by subtracting a moving average value of the detected signal in a second duration which is shorter than a first duration from a moving average value of the detection signal in the first duration, an extractor that extracts a feature point of a pulse wave based on the subtraction value, and a converter that converts a feature amount obtained based on the feature point to a blood pressure value. 1. A blood pressure measuring apparatus comprising:a sensor comprising a light source configured to emit light onto a living body and a light receiver configured to receive light from the living body, the received light carrying a first detection signal and a second detection signal and being represented as a pulse wave; anda signal processing device configured to extract a first feature point and a second feature point of the pulse wave based on the first detection signal and the second detection signal and convert a feature amount of the pulse wave to a blood pressure value based on the extracted first feature point and the extracted second feature point of the pulse wave,wherein the light source is further configured to output the first detection signal based on light of a first wavelength range and the second detection signal based on light of a second wavelength range that is shorter than the first wavelength range, andthe signal processing device is further configured to extract the first feature point based on a systolic blood pressure (SBP) that is based on the first detection ...

PULSE WAVE DETECTION DEVICE, BIOLOGICAL INFORMATION MEASURING DEVICE, WEARING AUXILIARY MEMBER OF PULSE WAVE DETECTION DEVICE

A pulse wave detector which is used while being attached to a wrist of a measurement subject includes: a body portion which includes a detecting section configured to detect a pulse wave from a radial artery of the measurement subject; a strip-like band which is configured to secure the body portion to the wrist; and an attachment auxiliary member which is configured to be attachable to and detachable from the band. In a secured state where the body portion is secured to the wrist with the band to which the attachment auxiliary member is attached, the attachment auxiliary member is contacted with a vicinity of an ulna or radius of the wrist. 1. A pulse wave detector which is used while being attached to a wrist of a measurement subject , the pulse wave detector comprising:a body portion which includes a detecting section configured to detect a pulse wave from a radial artery of the measurement subject;a strip-like band which is configured to secure the body portion to the wrist; andan attachment auxiliary member which is configured to be attachable to and detachable from the band,wherein the band is contacted with the wrist through the attachment auxiliary member at an attachment position of the attachment auxiliary member,wherein the attachment auxiliary member includes, in a contact surface with the wrist, both end portions of the attachment auxiliary member in a short-side direction of the band in a state of being attached to the band, and a concave portion formed between the both end portions to receive a protrusion of the ulna of the wrist,wherein in a secured state where the body portion is secured to the wrist with the band to which the attachment auxiliary member is attached, the attachment auxiliary member is secured such that the protrusion of the ulna is received in the concave portion and the both end portions are contacted with the wrist.2. The pulse wave detector according to claim 1 ,wherein a surface of the attachment auxiliary member to be contacted ...

PULSE WAVE DETECTION DEVICE AND BIOLOGICAL INFORMATION MEASURING DEVICE

A pulse wave detector includes: a body portion; a band which is wound around a wrist while the band is engaged with the body portion; a basal-end engaging portion which is disposed on one end portion of the body portion in a circumferential direction of the wrist, and with which a basal end portion of the band is engaged; an arbitrary-position engaging portion which is disposed on another end portion of the body portion in the circumferential direction, and with which an arbitrary position between the basal end portion and a tip end portion of the band is engaged in a folded back state; and an engagement member which causes the tip end portion to be detachably engaged with the band or the body portion in a state where the band which is folded back in the arbitrary-position engaging portion and the basal end portion overlap with each other. 1. A pulse wave detector which is used while being attached to a wrist of a measurement subject , the pulse wave detector comprising:a body portion which includes a detecting section configured to detect a pulse wave from a radial artery of the measurement subject;a band which is configured to be wound around the wrist in a state where the band is engaged with the body portion, so as to maintain a state where the detecting section is opposed to the radial artery;a basal-end engaging portion which is disposed on one of end portions of the body portion in a circumferential direction of the wrist, and with which a basal end portion of the band is engaged;an arbitrary-position engaging portion which is disposed on another end portion of the body portion in the circumferential direction, and with which an arbitrary position between the basal end portion engaged with the basal-end engaging portion and a tip end portion of the band is engaged in a folded back state; andan engagement member which is configured to cause the tip end portion to be detachably engaged with the band or the body portion in a state where the band which is folded ...

BIOLOGICAL SIGNAL PROCESSING METHOD AND BIOLOGICAL SIGNAL PROCESSING APPARATUS

There is provided a biological signal processing apparatus. The biological signal processing apparatus includes a biological signal extraction unit () configured to extract a biological signal from an electrocardiographic waveform measured by an electrocardiograph (), an averaging processing unit () configured to calculate averaged data using time-series data of the biological signals extracted by the biological signal extraction unit (), an abnormal value determination unit () configured to determine, for each data, whether the data of the biological signal extracted by the biological signal extraction unit () is appropriate, based on the averaged data calculated using the data of the biological signals that have occurred before the data, and an abnormal value processing unit () configured to perform one of deletion and interpolation of the data of the biological signal determined to be inappropriate by the abnormal value determination unit (). 1. (canceled)2. A biological signal processing method:a first step of extracting a biological signal from an electrocardiographic waveform of a living body;a second step of calculating averaged data using time-series data of the biological signals extracted in the first step;a third step of determining, for each data, whether the data of the biological signal extracted in the first step is appropriate, based on the averaged data calculated using the data of the biological signals that have occurred before the data; anda fourth step of performing one of deletion and interpolation of the data of the biological signal determined as inappropriate in the third step, a fifth step of performing averaging processing for values based on reciprocals of values of the time-series data of the biological signals extracted in the first step, and', 'a sixth step of calculating the averaged data from a reciprocal of a value obtained by the averaging processing in the fifth step., 'the second step including'}3. The biological signal ...

SYSTEMS AND METHODS FOR OBJECTIVELY DETERMINING HEARING THRESHOLDS

A system and method for determining hearing thresholds of people. The system and methods include the steps of presenting an auditory stimulus of a duration of less than one second to the person; spreading the power of the stimulus across a frequency range in alternating regions of high and low intensity; including in the stimulus at least two regions of high intensity; and measuring the transient evoked electrical response of the brain of the person. 116-. (canceled)17. A method of determining a hearing threshold of a person , the method comprising:presenting an auditory stimulus of a duration of less than one second to the person;spreading a power of the stimulus across a frequency range in alternating regions of high and low intensity;including at least two regions of high intensity in the stimulus; andmeasuring a transient evoked electrical response of a brain of the person.18. The method according to claim 17 , further comprising centering the at least two alternating regions of high and low intensity around a target frequency of interest.19. The method according to claim 17 , further comprising including at least three regions of high intensity in the stimulus.20. The method according to claim 17 , further comprising including narrow bands in the regions of high intensity.21. The method according to claim 17 , further comprising including pure tones in the regions of high intensity.22. The method according to claim 17 , further comprising presenting the stimulus to the person for a duration of less than 200 ms.23. The method according to claim 17 , further comprising presenting the stimulus to the person for a duration of less than 100 ms.24. The method according to claim 17 , further presenting the stimulus to the person for a duration of approximately 50 ms.25. A system for determining hearing thresholds of a person claim 17 , the system comprising:means for presenting an auditory stimulus of a duration of less than one second to the person;a power of the ...

System and method for noninvasive analysis of subcutaneous tissue

A method for noninvasive analysis of subcutaneous tissue includes irradiating a surface of the tissue with short wave infrared (SWIR) radiation in a first spectral band that is strongly absorbed by water, and with SWIR radiation in a second spectral band such that an interaction of the radiation in both spectral bands with a component of the tissue other than water is substantially identical. An intensity of the radiation in each of the spectral bands that emerges from the tissue is measured. A relative absorption by the tissue of radiation in one of spectral bands relative to absorption by the tissue of radiation in the other of the spectral bands is calculated. A state of the tissue is determined in accordance with the calculated relative absorption.

METHOD FOR LOCATING A BRAIN ACTIVITY ASSOCIATED WITH A TASK

The invention relates to a method for estimating the brain activity, from physiological signals, in particular magnetoencephalographic or electroencephalographic surfaces, which has, in certain predetermined areas of the cortex, considered as areas of interest, an improved accuracy with respect to other areas of the gridding. It enables a more accurate estimation to be obtained in the areas of the brain intended to be subjected to a particular treatment, for example to accommodate cortical electrodes. 1. A method for estimating the electrical activity within a tissue of a subject , whereinthe tissue is decomposed into a plurality of elementary areas and a transition matrix connecting the electrical activity in each area to a physiological signal around the tissue is determined,acquiring a plurality of physiological signals is performed thanks to a plurality of sensors disposed around the tissue,a noise covariance matrix is estimated;said method being characterised in that:elementary areas interest are defined among the elementary areas, the number of elementary areas of interest being strictly lower than the number of elementary areas,a source covariance matrix is established, so that the terms of its diagonal, corresponding to the elementary areas of interest, are lower than the other terms of its diagonal,the electrical activity in at least one elementary area is estimated from the physiological signals, the source covariance matrix and the noise covariance matrix2. The method for estimating the electrical activity within a tissue according to claim 1 , characterised in that the estimation is based on an MNE criterion.3. The method for estimating the electrical activity within a tissue according to claim 2 , characterised in that the noise matrix is calculated as the covariance matrix of the physiological signals over a time window in which the subject is at rest.4. The method for estimating the electrical activity within a tissue according to claim 2 , ...

METHODS AND SYSTEMS FOR NON-INVASIVE MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION BY TRANSMISSION OF MILLIMETER WAVES THROUGH HUMAN SKIN

A device is described for interrogating human skin using tight coupling between the transmitter and receiver of the millimeter waves (MMWs). Methods are provided to evaluate changes in the amplitude and/or phase of the transmitted MMWs in order to estimate the blood concentration of glucose. Using this device and the related methods, the blood glucose concentration or a change in the blood glucose concentration can be monitored for diagnosing diabetes mellitus and other metabolic disorders of carbohydrate metabolism characterized by either high blood glucose level (hyperglycemia) or low blood glucose level (hypoglycemia), as well as for monitoring (including self-monitoring) a metabolic disorder progression or an efficacy of treatment. 1. A device comprising:an electromagnetic wave transmitter, configured to be attached to biological tissue and transmit electromagnetic waves through biological tissue; andan electromagnetic wave receiver, configured to receive the electromagnetic waves transmitted through the biological tissue.2. The device of claim 1 , wherein the electromagnetic waves are in the microwave or millimeter wavelength range.3. The device of claim 2 , wherein the biological tissue is human skin.4. The device of claim 3 , further comprising an electromagnetic wave analyzer claim 3 , configured to analyze the electromagnetic waves before or after transmission.5. The device of claim 4 , further comprising a display for displaying results from the electromagnetic wave analyzer.6. The device of claim 5 , wherein the electromagnetic wave transmitter is configured to modulate claim 5 , and the electromagnetic wave receiver is configured to detect claim 5 , a magnitude and phase of the electromagnetic waves.7. The device of claim 6 , wherein the electromagnetic wave transmitter comprises an electromagnetic wave source and a waveguide or antenna.8. The device of claim 7 , wherein the electromagnetic wave source is chosen from the group comprising: a backward-wave ...

Heart rate measurement method and device, and computer readable storage medium

The present disclosure provides a heart rate measurement method, including: using a human body parameter acquisition device to collect user data; obtaining a time domain heart rate value according to a time domain characteristic of the user data; performing frequency domain transformation on the user data to obtain user frequency domain data, and obtaining a frequency domain heart rate value according to the user frequency domain data; and obtaining a heart rate measurement value according to the time domain heart rate value and the frequency domain heart rate value. The present disclosure further provides a heart rate measurement device and a computer readable storage medium.

Method and system for determining a parameter related to microcirculation function

The present invention provides a method for assessing at least one parameter related to the microcirculation function of a person, said method comprising the steps of a) determining an arrival time (AT) of a pulse wave, wherein the AT is the time between the onset of an activity of the heart that produces said pulse wave and the arrival of said pulse wave in a part of the body of said person; b) varying an applied pressure (P) on said part of the body over time and determining said AT as a function of applied pressure and time; and c) assessing said at least one parameter related to the microcirculation function based on said determination of AT and said AT as a function of applied pressure and time in steps a) and b). The present invention further provides a system for assessing at least one parameter related to the microcirculation function of a person.

Oximetry Probe with Tissue Depth Analysis

An oximeter probe includes a probe unit or a base unit and a probe tip where the probe tip has a number of sources and detectors that can be accessed individually or in differing combinations for measuring tissue oxygen saturation at different tissue depth in tissue. A processor of the oximeter probe controls a multiplexer that is coupled to the detectors for selectively collecting measurement information from the detectors via the multiplexer. The oximeter probe is user programmable via one or more input devices on the oximeter probe for selecting the particular sources and detectors to collect measurement information from by the processor. 1. A method comprising:providing a handheld oximeter housing;providing a processor housed in the handheld oximeter housing;providing a memory, housed in the handheld oximeter housing, coupled to the processor;providing a display, accessible from an exterior of the handheld oximeter housing, coupled to the processor;providing a battery, housed in the handheld oximeter housing;allowing for the battery to supply power to the processor, the memory, and the display;providing a first probe tip comprising a first source structure and a first plurality of detector structures having a first arrangement;coupling the first probe tip to the handheld oximeter housing;providing a second probe tip comprising a second source structure and a second plurality of detector structures having a second arrangement, wherein the first and second arrangements are different arrangements; andreplacing the first probe tip with the second probe tip via coupling the second probe tip to the handheld oximeter housing such that the first arrangement is changed to the second arrangement.2. The method of comprising:providing the first source structure and the first plurality of detector structures are on a first face of the first probe tip; andproviding the second source structure and the second plurality of detector structures are on a second face of the second ...

Pulse wave sensor and pulse wave measurement module

A pulse wave sensor includes a light sensor unit arranged to irradiate a living body with light from a light emitting unit and to detect reflected light or transmitted light from the living body by a light receiving unit, so as to generate a current signal corresponding to received light intensity, a pulse drive unit arranged to turn on and off the light emitting unit at a predetermined frame frequency and duty, a transimpedance amplifier arranged to convert the current signal into a voltage signal, and a mounting determination unit arranged to perform mounting determination by comparing an OFF voltage signal obtained by the transimpedance amplifier during an OFF period of the light emitting unit with a predetermined first threshold voltage.

NEUROLOGICAL EVENT DETECTION TOOLS FOR IMPLANTABLE MEDICAL DEVICES

An implantable device includes one or more electrodes to sense an electrical signal from a brain and a waveform analyzer to identify a half wave in the electrical signal; determine an amplitude and a duration of the half wave; determine if the amplitude satisfies a half wave amplitude criterion defined by a set of amplitude parameters comprising a minimum half wave amplitude and a maximum half wave amplitude; determine if the duration satisfies a half wave duration criterion defined by a set of duration parameters comprising a minimum half wave duration and a maximum half wave duration; and identify the half wave as a qualified half wave when the half wave amplitude criterion and the half wave duration criterion is satisfied. A neurological event may be detected based on one or more qualified half waves and electrical stimulation therapy may be delivered to the brain in response to the detection. 1. An implantable medical device , comprising:one or more electrodes configured to sense an electrical signal from a patient's brain; identify a half wave in the electrical signal;', 'determine an amplitude of the half wave and a duration of the half wave;', 'determine if the amplitude satisfies a half wave amplitude criterion defined by a set of amplitude parameters comprising a minimum half wave amplitude and a maximum half wave amplitude;', 'determine if the duration satisfies a half wave duration criterion defined by a set of duration parameters comprising a minimum half wave duration and a maximum half wave duration; and', 'identify the half wave as a qualified half wave when the half wave amplitude criterion and the half wave duration criterion is satisfied; and, 'an event detector comprising a waveform analyzer configured toa processor configured to determine, based at least in part on one or more identified qualified half waves, whether the electrical signal sensed from the patient's brain includes electrographic activity indicative of a neurological event.2. The ...

WEARABLE MEASUREMENT DEVICE AND MEASUREMENT METHOD

The wearable measurement device includes a mounting part for mounting the device to a human body, a variation detection part detecting a variation in distance from a predetermined portion of the human body, a posture detection part detecting a posture of the variation detection part in the case where the device is mounted to the human body through the mounting part, and a measurement part measuring the number of predetermined motions based on the variation detected by the variation detection part and the posture detected by the posture detection part. The variation detection part includes a light emitting unit and a light receiving unit, makes the light emitting unit emit light and the light receiving unit detect reflection light reflected at a predetermined portion, detects a distance from the predetermined portion and outputs an electric signal (voltage or current) in accordance with the detected distance at a predetermined sampling cycle. 15-. (canceled)6: A wearable measurement device , comprising:a mounting part for mounting the device to a human body;a variation detection part detecting a variation in distance from a predetermined portion of a human body;a posture detection part detecting a posture of the variation detection part in a case where the device is mounted to a human body through the mounting part; anda measurement part measuring the number of predetermined motions based on the variation detected by the variation detection part and the posture detected by the posture detection part.7: The wearable measurement device according to claim 6 , further comprising a decision part deciding a threshold in accordance with the posture detected by the posture detection part claim 6 , whereinthe measurement part is configured to count the number of predetermined motions if the variation detected by the variation detection part is larger than the threshold decided by the decision part.8: The wearable measurement device according to claim 6 , further comprising a ...

SYSTEM AND METHOD OF RESOLVING OUTLIERS IN NIRS CEREBRAL OXIMETRY

A system and method for non-invasively estimating the tissue blood oxygen saturation level of a human subject, including so-called “outliers”, whose physiological make-up causes previously-known techniques to generate invalid tissue blood oxygen saturation estimations. The system includes a computing device and a sensor. The sensor includes a light source configured to emit light of at least four different wavelengths, one at a time. The sensor also includes two light detectors, each positioned a different distances from the light source. Optical density measurements are taken by the light detectors and provided to the computing device. A first tissue blood oxygen saturation value is computed using the optical density measurements associated with three of the four wavelengths, and a second tissue blood oxygen saturation value is computed using the optical density measurements associated with four of the wavelengths. The first and second tissue blood oxygen saturation values are compared, and the human subject is identified as an “outlier” based upon that comparison. 112-. (canceled)13. A system for assessing tissue blood oxygen saturation levels , comprising:a computing device; a light source capable of selectively emitting a plurality of wavelengths of light, one wavelength at a time; and', 'a first light detector positioned a first distance from said light source and a second light detector positioned a second distance from said light source, said second distance being greater than said first distance;, 'a sensor in communication with said computing device, said sensor being configured to be attached to a human subject and havingsaid computing device having a memory for storing an algorithm and a processor for executing instructions associated with said algorithm, said algorithm comprising the following steps:causing said light source to emit light of a plurality of wavelengths, one wavelength at a time, into a human subject;receiving optical density measurements ...

METHOD AND SYSTEM FOR SENSING RADIO WAVE IN DIAGNOSTIC IMAGING OF BREAST CANCER

Provided is a method of sensing a radio wave in diagnostic imaging of breast cancer, including arranging a plurality of transmitting and receiving antennas along a periphery of a breast, transmitting a radio wave signal from at least one first antenna among the plurality of transmitting and receiving antennas, receiving a scattered wave signal for the radio wave signal from the remaining antennas, other than the first antenna, among the plurality of transmitting and receiving antennas, and rotating the plurality of transmitting and receiving antennas by a predetermined angle. 1. A method of sensing a radio wave in diagnostic imaging of breast cancer , the method comprising:arranging a plurality of transmitting and receiving antennas along a periphery of a breast;transmitting a radio wave signal from at least one first antenna among the plurality of transmitting and receiving antennas;receiving a scattered wave signal for the radio wave signal from the remaining antennas, other than the first antenna, among the plurality of transmitting and receiving antennas; androtating the plurality of transmitting and receiving antennas by a predetermined angle.2. The method of claim 1 , wherein the rotating of the plurality of transmitting and receiving antennas comprises re-arranging the plurality of transmitting and receiving antennas by rotating the plurality of transmitting and receiving antennas by the predetermined angle along the periphery of the breast.3. The method of claim 1 , further comprising:moving the plurality of transmitting and receiving antennas by a predetermined distance in a depthwise direction of the breast after rotating the plurality of transmitting and receiving antennas.4. The method of claim 1 , further comprising:setting at least one new first antenna among the remaining antennas, other than the first antenna transmitting the radio wave signal, after receiving the scattered wave signal.5. The method of claim 1 , wherein the receiving of the scattered ...

PHOTOACOUSTIC IMAGE GENERATION APPARATUS, SYSTEM AND METHOD

A photoacoustic wave induced in a subject to be examined by illumination of the subject to be examined with light is detected. A first photoacoustic image corresponding to a frequency component less than or equal to a predetermined frequency and a second photoacoustic image corresponding to a frequency component higher than a predetermined frequency are generated based on a detection signal of the detected photoacoustic wave. The first photoacoustic image and the second photoacoustic image are combined together by placing, on a pixel in the first photoacoustic image the pixel value of which is less than or equal to a threshold, a pixel in the second photoacoustic image corresponding to the pixel in the first photoacoustic image. 1. A photoacoustic image generation apparatus comprising:an image generation unit that generates photoacoustic images based on a detection signal of a photoacoustic wave induced in a subject to be examined by illumination of the subject to be examined with light, and which generates a first photoacoustic image corresponding to a frequency component less than or equal to a first predetermined frequency and a second photoacoustic image corresponding to a frequency component higher than a second predetermined frequency; andan image combination unit that combines the first photoacoustic image and the second photoacoustic image together by placing, on a pixel in the first photoacoustic image the pixel value of which is less than or equal to a threshold, a pixel in the second photoacoustic image corresponding to the pixel in the first photoacoustic image.2. The photoacoustic image generation apparatus claim 1 , as defined in claim 1 , wherein the image generation unit includes:an original image generation unit that generates, based on the detection signal of the photoacoustic wave, a third photoacoustic image including both of the component of less than or equal to the first predetermined frequency and the component of higher than the second ...

System and Method for Providing Biofeedback Controls to Various Media Based Upon the Remote Monitoring of Life Signs

A system and method for generating biofeedback using feedback signals created by at least one media device. A subject person is monitored to obtain biometric data. The biometric data is used to generate a biometric waveform. The biometric waveform is used to generate control signals. The control signals are used to regulate audio signals, lighting, audiovisual imagery and/or auxiliary devices so that these feedbacks are altered to represent some waveform characteristic embodied by the biometric waveform. The subject person will hear and/or see the feedback and will better be able to control their body and mind. 1. A method of generating biofeedback using feedback signals created by at least one media device , said method comprising the steps of:monitoring a subject person to obtain a biometric waveform, wherein said biometric waveform has waveform characteristics;utilizing said biometric waveform to generate control signals; andcontrolling said at least one media device with said control signals, wherein said at least one media device broadcasts said feedback signals as directed by said control signals.2. The method according to claim 1 , wherein said at least one media device is selected from a group consisting of audio devices claim 1 , lighting devices and audiovisual devices.3. The method according to claim 1 , wherein said at least one media device is an audio device that broadcasts an audio signal that is selectively altered by said control signals to correspond with at least one of said waveform characteristics of said biometric waveform.4. The method according to claim 1 , wherein said at least one media device is an audio device that broadcasts an audio signal with a pitch frequency that is selectively altered by said control signals to correspond with at least one of said waveform characteristics of said biometric waveform.5. The method according to claim 1 , wherein said at least one media device is an audio device that broadcasts an audio signal that is ...

BIOLOGICAL INFORMATION ANALYZING SYSTEM, BIOLOGICAL INFORMATION PROCESSING SYSTEM, AND BIOLOGICAL INFORMATION ANALYZING DEVICE

A biological information analyzing system includes: a reception unit receiving pulse wave information which is collected by a pulse wave measurement device worn by a user; a processing unit performing analysis processing with respect to atrial fibrillation of the user on the basis of the pulse wave information and generating browsing information of an analysis result of the analysis processing; and an output unit outputting the generated browsing information. 1. A biological information analyzing system comprising:a reception unit receiving pulse wave information which is collected by a pulse wave measurement device worn by a user;a processing unit performing analysis processing with respect to atrial fibrillation of the user on the basis of the pulse wave information and generating browsing information of an analysis result of the analysis processing; andan output unit outputting the generated browsing information.2. The biological information analyzing system according to claim 1 ,wherein the processing unit generates the browsing information including total onset time information of the atrial fibrillation.3. The biological information analyzing system according to claim 2 ,wherein the processing unit generates the browsing information including information which indicates a change in the total onset time information in chronological order.4. The biological information analyzing system according to claim 1 ,wherein the processing unit generates the browsing information including continuous onset time information of the atrial fibrillation.5. The biological information analyzing system according to claim 4 ,wherein the processing unit generates the browsing information including information in which the continuous onset time information is associated with date and time.6. The biological information analyzing system according to claim 1 ,wherein the reception unit receives body motion information of the user which is collected by the pulse wave measurement device ...

System and Method for Facilitating Observation of Monitored Physiologic Data

Present embodiments are directed to a system and method capable of detecting and graphically indicating physiologic patterns in patient data. For example, present embodiments may include a monitoring system that includes a monitor capable of receiving input relating to patient physiological parameters and storing historical data related to the parameters. Additionally, the monitoring system may include a screen capable of displaying the historical data corresponding to the patient physiological parameters. Further, the monitoring system may include a pattern detection feature capable of analyzing the historical data to detect a physiologic pattern in a segment of the historical data and capable of initiating a graphical indication of the segment on the screen when the physiologic pattern is present in the segment. 119.-. (canceled)20. A pulse oximeter , comprising:an input for receiving a photoplethysmograph (PPG) signal from a pulse oximetry sensor, wherein the pulse oximetry sensor detects light attenuated by a patient; process the PPG signal to generate oxygen saturation data,', 'analyze the oxygen saturation data to detect reciprocations in the oxygen saturation data, each reciprocation defined by a fall peak, a nadir, and a rise peak,', 'qualify each of the detected reciprocations based on qualification criteria, maintain a count of qualified reciprocations, and', 'determine an occurrence of a clustering state indicative of a presence of ventilatory instability based on the count; and, 'computer program instructions recorded thereon for causing the pulse oximeter to, 'non-transitory computer-readable medium comprisinga display for displaying a ventilatory instability notification while the clustering state is determined to be occurring.21. The pulse oximeter of claim 20 , wherein the non-transitory computer-readable medium further comprises computer program instructions recorded thereon for causing the pulse oximeter to determine a scoring metric associated ...

NEUROPHYSIOLOGICAL SIGNATURES FOR FIBROMYALGIA

Described herein are novel fMRI-based neurologic signatures that predict fibromyalgia (FM), clinical severity, and treatment outcomes. Further described are methods for diagnosing FM and for predicting or evaluating efficacy of a treatment of FM based on the neurologic signature. 1. A method of detecting fibromyalgia (FM) in a subject comprising: i. a pressure pain stimulus, and', 'ii. a non-painful, multisensory stimulus comprising visual, auditory and tactile-motor stimulation;, 'a. applying a stimulus to the subject, wherein the stimulus is selected from at least one ofb. detecting brain activity of the subject in response to the stimulus using functional Magnetic Resonance Imaging (fMRI) and generating a brain map of the subject representing the brain activity of the subject in response to the stimulus;c. comparing the brain map of the subject to a neurologic signature map, wherein the neurologic signature map represents brain activity indicative of FM in the subject; and,d. diagnosing FM in the subject if the brain map of the subject is at least 70% identical to the neurologic signature map indicative of FM.2. The method of claim 1 , wherein the neurologic signature map comprises an fMRI pattern created in a subject known to have FM in response to pain created by the application of pressure to a surface of the subject and that is at least 70% identical to the fMRI patterns shown in .3. The method of claim 2 , wherein the applied pressure is about 4.5 kg/cm.4. The method of claim 2 , wherein the fMRI pattern is created by detecting brain activity in the subject known to have FM in brain regions of major targets of ascending nociceptive afferents selected from the group consisting of the thalamus claim 2 , primary and secondary somatosensory regions (SI/SII) claim 2 , posterior claim 2 , mid and anterior insula and adjacent opercula claim 2 , midbrain claim 2 , dorsal anterior cingulate cortex claim 2 , inferior frontal gyms claim 2 , amygdala claim 2 , and ...

BIOLOGICAL INFORMATION EXTRACTING DEVICE AND BIOLOGICAL INFORMATION EXTRACTING SYSTEM

A biological information extracting device which is provided at a head-mounted member mounted on a head of a person (subject) and includes a camera that captures temporally successive images including at least a part of a face of the person as an object; a region selector that selects a skin color region from the image captured by the camera; a pulse wave measurer that measures a pulse wave signal of the person based on image data of the skin color region; and a data transmitter that transmits the pulse wave signal to a predetermined transmission destination. The camera is disposed to face a side surface of the face of the person and is set to capture a part (cheek of the face) of the side surface of the face. 1. A biological information extracting device which is provided at a head-mounted member mounted on a head of a subject and extracts biological information of the subject from information obtained without coming into contact with the subject , the device comprising:a camera that captures temporally successive images including at least a part of a face of the subject as an object;a region selector that selects a skin color region from the image captured by the camera; anda data transmitter that transmits biomaterial-related data relating to a biomaterial of the subject extracted based on the skin color region to a predetermined transmission destination,wherein the camera is disposed to face a side surface of the face of the subject.2. The biological information extracting device of claim 1 ,wherein the camera is set to capture a part of the side surface of the face.3. The biological information extracting device of claim 2 ,wherein a part of the face is a cheek of the face.4. The biological information extracting device of claim 1 ,wherein the biomaterial-related data is time series image data of the skin color region.5. The biological information extracting device of claim 4 , further comprising:a pulse wave measurer that measures a pulse wave signal of the ...

APPARATUS, TERMINAL AND BIOINFORMATION SYSTEM

An apparatus that stores information on a pulse wave of a living body is provided, the apparatus including: a receiving unit that receives a bias signal and a fundamental wave signal of the pulse wave, respectively; and a storage unit that stores the bias signal and fundamental wave signal. A terminal is provided, the terminal including: an acquiring unit that acquires a pulse wave signal of a living body; a calculating unit that calculates a bias signal and a fundamental wave signal of the pulse wave from the pulse wave signal; and a transmitting unit that transmits the bias signal and the fundamental wave signal to an apparatus provided outside. In addition, a bioinformation system including an apparatus according to the present specification and a terminal according to the present specification is provided. 1. An apparatus that stores information on a pulse wave of a living body , the apparatus comprising:a receiving unit that receives a bias signal and a fundamental wave signal of the pulse wave, respectively; anda storage unit that stores the bias signal and fundamental wave signal.2. The apparatus according to claim 1 , wherein the storage unit stores a higher harmonic wave signal of the pulse wave.3. The apparatus according to claim 2 , wherein the storage unit stores a second higher harmonic wave signal and a third higher harmonic wave signal of the pulse wave claim 2 , respectively.4. The apparatus according to claim 2 , wherein the storage unit stores a frequency of the fundamental wave signal and an amplitude and a phase of the higher harmonic wave signal.5. The apparatus according to claim 1 , wherein the storage unit stores reliability of the pulse wave.6. The apparatus according to claim 1 , wherein the storage unit stores information on a pulse wave acquired from optical information of the living body.7. The apparatus according to claim 6 , wherein the storage unit stores information on a pulse wave acquired from video information of the living body.8 ...

Thermal Patient Signal Analysis

Disclosed herein is a framework for facilitating thermal patient signal analysis. In accordance with one aspect, the framework receives patient signal data including thermal signal data. The framework then segments a waveform of the thermal signal data into portions and extracts thermal parameters based on the segmented portions. The framework then determines one or more thermal indices based at least in part on the thermal parameters and generates a report that presents cardiac event detection results determined based at least in part on the one or more thermal indices. 1. A system for patient signal analysis , comprising:a patient monitor including a sensor system that simultaneously acquires multiple types of patient signal data including thermal signal data from a patient; and a non-transitory memory device for storing computer readable program code, and', synchronizing a first waveform of a first type of the patient signal data with a second waveform of a second type of the patient signal data by determining time durations between peaks of the first waveform and peaks of the second waveform within a predetermined time window,', 'determining a synchronicity value based at least in part on the time durations; and', 'generating a report that presents cardiac event detection results determined based at least in part on the synchronicity value., 'a processor in communication with the memory device, the processor being operative with the computer readable program code to perform steps including'}], 'a computer system communicatively coupled to the patient monitor to receive the patient signal data, wherein the computer system includes'}2. The system of wherein the patient monitor comprises a smart device.3. The system of wherein the sensor system comprises multiple thermal sensors that acquire different types of the thermal signal data from different locations on a body surface.4. The system of wherein the first and second types of the patient signal data comprise ...

Bootstrapping a simulation-based electromagnetic output of a different anatomy

Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.

SYSTEM AND METHOD OF CANNABIS MONITORING

A system for monitoring cannabis safety for a user comprising: an intake device communicatively coupled to a cannabis analysis subsystem via a network; wherein said intake device collects session data from the user and transmits said collected session data to the cannabis analysis subsystem; and said cannabis analysis subsystem performs analysis of said transmitted session data and communicates a reading to said user. 1. A system for monitoring cannabis safety for a user comprising:an intake device communicatively coupled to a cannabis analysis subsystem;wherein said intake device collects session data from the user and transmits said collected session data to the cannabis analysis subsystem; andsaid cannabis analysis subsystem performs analysis of said transmitted session data and communicates a personalized report to said user based on the analysis.2. The system of claim 1 , wherein said cannabis safety self-monitoring device is configured to detect one or more concentrations of one or more metabolites from one or more exhaled samples provided by the user.3. The system of claim 1 , wherein said cannabis analysis subsystem comprises at least one usage processing subsystem coupled to a database;wherein said database stores data corresponding to said user's usage history and elimination patterns; andsaid analysis is performed based on said user's usage history and elimination patterns.4. The system of claim 2 , wherein said cannabis safety self-monitoring device performs regression analysis to determine at least one metabolite elimination t ½beta.5. The system of claim 2 , wherein said cannabis safety self-monitoring device implements one or more sobriety algorithms.6. The system of claim 1 , whereinsaid intake device is communicatively coupled to a mobile device associated with said user;said mobile device is communicatively coupled to said mobile device; andsaid cannabis analysis subsystem communicates said personalized report to said mobile device.7. The system of ...

One repetition maximum (1rm) estimating apparatus and method

A one repetition maximum (1RM) estimating apparatus includes a potential signal receiving unit configured to receive a potential signal of a muscle from a sensor attached to a user, and a 1RM estimating unit configured to estimate a 1RM of the user based on the potential signal.

SYSTEM AND METHOD FOR PHYSIOLOGICAL FEATURE DERIVATION

The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject based on physiological features and personalized models. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on a pulse wave of the subject may be received. A personalized model for the subject may be designated. Effective physiological features of the subject based on the plurality of second signals may be determined. A blood pressure of the subject based on the effective physiological features and the designated model for the subject may be calculated. 1. A device for monitoring blood pressure comprising:memory storing instructions; and receiving a plurality of second signals representing time-varying information on a pulse wave of a subject;', 'determining a plurality of effective physiological features of the subject based on the plurality of second signals;', 'designating a personalized model for the subject from a plurality of models based on cost function of each of the plurality of models and the plurality of effective physiological features; and', 'calculating a blood pressure of the subject based on the effective physiological features and the designated personalized model for the subject., 'at least one processor that executes the instructions to perform operations comprising2. The device of claim 1 , wherein the plurality of effective physiological features of the subject are an optimal subset of a plurality of physiological features of the subject that leads to minimal cross-validated prediction errors.3. The device of claim 1 , wherein the cost function is a standard deviation of prediction errors of test data claim 1 , the test data being the plurality of effective physiological features with the ...

System and method to measure and monitor neurodegeneration

A system to measure and monitor neurodegeneration of a subject, which includes: an acquisition module configured to acquire electroencephalographic signals with multiple EEG channels from a subject perceptually isolated; a calculation module configured to extract at least one EEG metric representative of neurodegeneration; and an evaluation module configured to evaluate the at least one EEG metric and extract a neurodegeneration index.

HEAD MOUNTABLE DEVICE

A head mountable device for detecting a functional disorder of the brain in a patient, comprising an LED display; at least one electrode for measuring electrical potential; the device being configured to be mountable on the head of a patient such that when mounted on the head of a patient the LED display is positioned before the eyes of a patient and the at least one electrode is positioned adjacent to the occipital lobe of the patient. 1. A head mountable device for detecting a functional disorder of the brain in a patient , comprising:an LED display;at least one electrode for measuring electrical potential;the device being configured to be mountable on the head of a patient such that when mounted on the head of a patient the LED display is positioned before the eyes of a patient and the at least one electrode is positioned adjacent to the occipital lobe of the patient.2. A head mountable display according to wherein the LED display is configured to display a visual stimulus.3. A head mountable device according to wherein the visual stimulus is a light pulse.4. A head mountable device according to wherein the visual stimulus is white light.5. A head mountable device according to wherein the visual stimulus pulses at a frequency of between 5 Hz to 60 Hz.6. A head mountable device according to wherein the visual stimulus pulses at a frequency of 15 Hz.7. A head mountable device according to any preceding claim wherein the at least one electrode is configured to detects electrical signals from the occipital lobe of the patient in response to the visual stimulus when the device is mounted on the head of a patient.8. A head mountable device according to any preceding claim comprising a processor configured to receive electric potential signal data from the at least one electrode.9. A head mountable device further comprising a memory claim 3 , the memory being configured to store predetermined electrical potential values claim 3 , wherein the processor is configured to ...

Advanced Electronic Instrumentation for Electrical Impedance Myography

Embodiments of devices and methods for evaluating tissue are disclosed. In one embodiment, a method for measuring a characteristic of a tissue may include passing a current through the tissue, measuring a signal corresponding to the voltage resulting from passing the current through the tissue, analyzing current passed through the tissue and resulting voltage to determine the electrical characteristics of the tissue; and analyzing the electrical characteristics of the tissue to determine a status of the tissue. Disposable sensors are disclosed.

Method and device for continuous blood pressure monitoring and estimation

A method and device is provided for the continuous estimation of the blood pressure using a noninvasive technique. The method involves sensing of the displacement signal generated by the palpation of the radial artery. The radial artery is modelled as a cylindrical voight type viscoelastic tissue for the estimation of the personalized blood pressure. The model includes the displacement signal and a set of parameters as an input. The set of parameters include a mean radius of the artery, a radius at zero mmHg, a viscoelastic damping parameter, an elasticity of the artery and a thickness of wall of artery. The method involves the optimization of the set of parameters using heuristic optimization techniques, which helps in the estimation of the systolic and diastolic blood pressure. The method and device can also be personalized for individualized monitoring and estimation of the blood pressure of the person.

Cardiovascular Detection System and Method

The detection and diagnosis of a variety of cardiovascular disorders and levels of heart condition, using a novel method and system, according to a comprehensive analysis of cardiac electrical signal via the frequency domain, time domain, spatial domain.

Machine learning using clinical and simulated data

Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.

Synchronous Detection Circuit And Method For Determining A Bio-Impedance Of A Biological Tissue

Embodiments of synchronous detection circuits and methods are provided for extracting magnitude and phase information from a waveform. One embodiment of a synchronous detection circuit includes a driver circuit, an analog-to-digital converter (ADC) and a controller. The driver circuit is configured to supply an input waveform at an input frequency to a load. The ADC is coupled to receive an output waveform from the load, and configured for generating four digital samples, each spaced 90° apart, for every period of the output waveform. The controller is configured for setting an oversampling rate (OSR) of the ADC, so that the ADC generates an integer number, M, of sub-samples for each digital sample generated by the ADC, where the integer number, M, of sub-samples is inversely proportional to the input frequency of the input waveform. The controller is further configured to use the digital samples generated by the ADC to extract magnitude and phase information from the output waveform.

Apparatus and method for obtaining bio-information

An apparatus for obtaining bio-information may include a pulse wave sensor including a light source and a detector. The light source is configured to emit multi-wavelength light to an object of interest and the detector is configured to detect light reflected from the object. In addition, the apparatus may include a processor configured to obtain a change in volume of a blood vessel based on one or more of quantity of detected multi-wavelength light and absorbance coefficients of respective wavelengths of the multi-wavelength light and obtain bio-information based on the measured change in volume of the blood vessel.

SYSTEMS AND METHODS FOR CLUSTERING WAVEFRONT SIGNALS IN ELECTROPHYSIOLOGICAL MAPS

A system and method for clustering wavefront signals in an electrophysiological map of a cardiac tissue are provided. The system and method include receiving an electrophysiological map of the cardiac tissue, displaying propagation of the wavefront signals as a plurality of velocity vectors, discretizing the received electrophysiological map into a plurality of sections, clustering the velocity vectors into at least one group within each section based on predefined criteria, and generating a trend line representative of each group of clustered velocity vectors within each section in the electrophysiological map. 1. A method for clustering wavefront signals in an electrophysiological map of a cardiac tissue , comprising:providing a processor configured to receive an electrophysiological map of the cardiac tissue;displaying propagation of the wavefront signals as a plurality of velocity vectors;discretizing the received electrophysiological map into a plurality of sections;clustering the velocity vectors into at least one group within each section based on predefined criteria; andgenerating a trend line representative of each group of clustered velocity vectors within each section in the electrophysiological map.2. The method of claim 1 , wherein the cardiac tissue is an atrial chamber.3. The method of claim 1 , wherein the received electrophysiological map is a 3D map of local activation times associated with the cardiac tissue.4. The method of claim 1 , wherein the electrophysiological map is discretized into a plurality isochronal sections.5. The method of claim 4 , wherein the electrophysiological map is discretized based on the direction of the velocity vectors.6. The method of claim 1 , wherein clustering further comprises applying a clustering algorithm to group the velocity vectors.7. The method of claim 1 , wherein the predefined criteria for clustering the velocity vectors comprises at least one of a predefined proximity claim 1 , a common direction claim 1 ...

COMPARTMENT-SPECIFIC DOWN-SCALING OF HIGH-FREQUENCY CONDUCTIVITY TO LOW-FREQUENCY CONDUCTIVITY FOR EEG

In an embodiment, deriving low frequency conductivity based on radio frequency conductivity derived from Electric Properties Tomography for use in source localization. 1. A computing device comprising:a memory configured to store instructions; andone or more processors configured to execute the instructions to:measure radio frequency conductivity based on Electric Properties Tomography;segment areas of a head differing in conductivity; andderive low frequency conductivity based on application of plural Cole-Cole models to the measured radio frequency conductivity for each of one or more segmented areas of the head, the low frequency conductivity applicable to source localization.2. The computing device claim 1 , wherein the one or more processors are further configured to execute the instructions to receive magnetic resonance data and apply the Electric Properties Tomography to the magnetic resonance data.3. The computing device of claim 1 , wherein the one or more processors are further configured to execute the instructions to apply the derived low frequency conductivity to electro-encephalography data for the source localization.4. The computing device claim 1 , wherein the derived low frequency conductivity applied to the electro-encephalography data is patient-specific.5. The computing device of claim 1 , wherein the low frequency conductivity comprises a frequency at or proximal to 1000 kilohertz and the measured radio frequency conductivity comprises a frequency at or proximal to 100 megahertz.6. The computing device of claim 1 , wherein the one or more processors are further configured to execute the instructions to segment areas of a head by segmenting tissue classes in a head for which one or more tissue-specific transfer functions are applied.7. The computing device of claim 1 , wherein the one or more processors are further configured to execute the instructions to:parameterize frequency dependence of electric properties by superposing four of the Cole- ...

METHOD AND SYSTEM FOR ASSESSING THE STATE OF HEALING OF A FRACTURED LONG BONE

A method of assessing the state of healing of a fractured long bone in a limb, including the steps of: applying a known force to the limb; using vibration sensors attached on either side of the limb to produce output signals generated in response to the known force from the output signals of the vibration sensors; from the output signals, generating frequency domain waveforms for a) phase difference between vibration sensor output signals, b) coherence of the vibration sensor output signals, and c) cross-spectra of the vibration sensor output signals; identifying in-phase and the out-of-phase responses of the vibration sensors from phase differences in the phase difference waveform at frequencies corresponding to peaks in the cross-spectra waveform; verifying coherent modes from the magnitude of the coherence waveform; and generating bone healing data, including using the magnitude of the coherence waveform and the phase differences as weighting-functions, computing a healing index value representing the state of healing of the bone. 1. A method of assessing the state of healing of a fractured long bone in a limb , including the steps of:applying a known force to the limb;using vibration sensors attached on either side of the limb to produce output signals generated in response to the known force from the output signals of the vibration sensors;from the output signals, generating frequency domain waveforms for phase difference between vibration sensor output signals,coherence of the vibration sensor output signals, andcross-spectra of the vibration sensor output signals;identifying in-phase and the out-of-phase responses of the vibration sensors from phase differences in the phase difference waveform at frequencies corresponding to peaks in the cross-spectra waveform;verifying coherent modes from the magnitude of the coherence waveform; andgenerating bone healing data, includingusing the magnitude of the coherence waveform and the phase differences as weighting- ...

Microangiography method and system based on full-space modulation spectrum splitting and angle compounding

A microangiography method and system based on full-space modulation spectrum splitting and angle compounding is disclosed. Label-free three-dimensional optical coherence tomography angiography is realized by combining the three-dimensional space resolution capability of an optical coherence tomography and the motion recognition capability of a dynamic scattering technology. Probe light of different incident angles is encoded with a transverse scanning modulation spectrum in a spatial frequency domain, incident angle-resolved sub-angiograms which are independent of one another are obtained by splitting the modulation spectrum, and an angiogram with multiple space angles compounded is realized. Conjugate mirror images are removed from a depth (z) domain, a complex-valued OCT interference spectra are reconstructed, the full-space modulation spectrum is obtained in the spatial frequency domain, and the overlap of the modulation spectrum conjugate mirror images is avoided. And the absolute flow velocity of blood flow can be measured through a multi angle-resolved probing technology. 1. A microangiography method based on full-space modulation spectrum splitting and angle compounding , comprising following steps of:1) reconstructing complex-valued interference spectrum and obtaining a full-space transverse scanning modulation spectrum in a spatial frequency domain by removing conjugate mirror images in an OCT (Optical Coherence Tomography) depth (z) domain;2) encoding a probe light of different incident angles with the full-space transverse scanning modulation spectrum in the spatial frequency domain and obtaining an incident angle-resolved OCT interference subspectra independent of one another by splitting a modulation spectrum;3) obtaining independent sub-angiograms of multi-angle-resolved based on transverse scanning modulation spectrum splitting by combing a modulation spectrum splitting technology and an optical coherence tomography angiography technology in the step ...

PORTABLE RAPID NEUROLOGICAL AND MOTOR FUNCTION SCREENING APPARATUS

In an aspect, a neurological data collecting apparatus is described. A plurality of electronically interconnected interface panels configured to selectively display stimuli and accept input is provided. An interface panel frame supports the plurality of interface panels and aggregates the plurality of interface panels into a user interface screen that extends into the user's peripheral vision when the user is standing within a predetermined distance from the user interface screen. A supporting stand is connected to the user interface screen. The supporting stand includes a height adjustment mechanism for adjusting the height of the user interface screen to eye level of the user. A control unit electronically connects the user interface screen to a computer. 1. A neurological data collecting apparatus , comprising:a plurality of electronically interconnected interface panels configured to selectively display stimuli and accept input;an interface panel frame supporting the plurality of interface panels and aggregating the plurality of interface panels into a user interface screen that extends into the user's peripheral vison when the user is standing within a predetermined distance from the user interface screen;a supporting stand connected to the user interface screen, including a height adjustment mechanism for adjusting the height of the user interface screen to eye level of the user; anda control unit electronically connecting the user interface screen to a computer.2. The apparatus as set forth in claim 1 , wherein each interface panel includes an electronically controlled stimulus display and corresponding input sensors that may be associated with individual stimuli.3. The apparatus as set forth in claim 2 , wherein the stimulus display includes a plurality of LEDs embedded into a printed circuit board and the input sensors includes a resistive touch screen that covers the entire stimulus display.4. The apparatus as set forth in claim 1 , wherein each interface ...

WEANING FROM VENTILATION USING CAPNOGRAPHY

Devices and systems for monitoring weaning of a subject from a respiratory ventilator including a processing logic configured to characterize distinct patterns in a series of COwaveforms, the distinct patterns indicative of the effectiveness of a weaning process; and to provide an indication relating to the effectiveness of the weaning process. 1. A method for monitoring weaning of a subject from a respiratory ventilator , the method comprising:{'sub': '2', 'characterizing distinct patterns in a series of COwaveforms obtained from expired breath of a subject undergoing respiratory ventilation weaning; and'}providing an indication relating to the effectiveness of the weaning process.2. The method of claim 1 , wherein said distinct patterns are indicative to the effectiveness of a weaning process and wherein said distinct patterns are selected from a group consisting of “sigh events” claim 1 , “spike events” and “pools”3. The method of claim 1 , further comprising providing a signal to a ventilator at least partially based on the characterized distinct patterns in the series of COwaveforms and thus inducing a change in one or more parameters of the ventilator.4. The method of claim 3 , wherein said change in one or more parameters of the ventilator comprises a change in the level of support to the ventilation claim 3 , allowing the patient to rest from weaning attempts claim 3 , changing a mode/program of weaning or any combination thereof.5. The method of claim 3 , wherein providing a signal to the ventilator is further based on one or more additional parameters selected from the group consisting of: age of the subject claim 3 , medical condition of the subject claim 3 , medical history of the subject and medications administered to the subject.6. The method of claim 3 , wherein providing a signal to the ventilator is further based on one or more additional parameters selected from the group consisting of: respiration rate claim 3 , tidal volumes claim 3 , minute ...