КОМПЕНСАЦИЯ ДВИЖЕНИЯ В ФУНКЦИОНАЛЬНОМ ФОРМИРОВАНИИ ИЗОБРАЖЕНИЙ

Группа изобретений относится к медицине и медицинской технике, а именно к способам и устройствам для формирования изображений с компенсацией движения, вызываемым естественными дыхательными и сердечными циклами. Способ формирования диагностического изображения содержит генерацию множества изображений сердца в каждой из множества фаз дыхания и сердца с использованием первой методики формирования изображения; преобразование изображений, которые имеют общую фазу сердца и различные фазы дыхания, в последовательность изображений с компенсацией дыхательного движения на множестве фаз сердца и на выбранной общей фазе дыхания; преобразование последовательности изображений с компенсацией дыхательного движения согласно модели формы и движения сердца для генерации последовательности изображений с компенсацией дыхательного и сердечного движения в выбранной общей фазе сердца и в выбранной общей фазе дыхания; и объединение этих изображений. Для выполнения способа используют устройство формирования диагностического ...

OPTICAL SENSOR TO NOT INVASIVEN THE BLUTDRUCKMESSUNG AND CALIBRATION PROCEDURE

BLUTSTRÖMUNGS GATE MRI

TOMOGRAPHI PICTURE RECONSTRUCTION WITH INTERPOLATION BETWEEN PROJECTION OPINIONS

Apparatus for monitoring chf patients using bio-impedance technique

METHOD AND APPARATUS FOR INVASIVE DEVICE TRACKING USING ORGAN TIMING SIGNAL GENERATED FROM MPS SENSORS

SYSTEM AND METHOD FOR COMPUTER AIDED SEPTAL DEFECT DIAGNOSIS AND SURGERY FRAMEWORK

Certain embodiments of the present invention provide systems and methods for detecting septal defects. In an embodiment, the method (200) may include acquiring gated MRI data and heart atlas data (210). A registration of the gated MRI data and the heart atlas data may be performed (220) as well as a flow-balance measurement (240). An atrial septal detection and ventricular septal detection (250) may be performed, as well as a septal measurement (260). A diagnostic report may be generated detailing the location and properties of the septal defects (270). A physician may utilize the diagnostic report for surgery planning (510-530). After surgery, the diagnostic report may be compared with a post-surgery diagnostic report to determine the success of the surgery (610-630).

ALGORITHMIC APPROACH FOR ESTIMATION OF RESPIRATION AND HEART RATES

One or more aspects of the disclosure relate to monitoring a resting subject's respiration and heart rate through an impulse radio ultra-wideband (IR-UWB) radar in a noninvasive fashion, in order to infer the corresponding health status including heart rate and respiration rate. Any other reflectance technology may be used. These two cardiopulmonary vital signs are derived based on the processing of recorded waveforms that are collected by the IR-UWB radar or any other reflectance technology system, after getting reflected-off the resting subject's body or relevant body part. A novel algorithm that processes the recorded waveforms is proposed to extract these vitals' signals and, accordingly, estimate their rates. This algorithm includes at least three major stages: i) noise reduction, ii) respiration rate estimation, and iii) heart rate estimation. Furthermore, the algorithm addresses the effects of harmonics and intermodulation between the breathing and heartbeat signals without requiring ...

ARTERY IMAGING SYSTEM

Retrospective sorting of 4d ct into breathing phases based on geometric analysis of imaging fiducials

AUTOMATICALLY DETERMINING 3D CATHETER LOCATION AND ORIENTATION USING 2D FLUOROSCOPY ONLY

DIAGNOSTIC IMAGING APPARATUS AND IMAGE DISPLAY METHOD

This diagnostic imaging apparatus is provided with: an image pickup unit that images a region of the subject and generates image data; a biosignal-acquiring unit that acquires biosignal data that is a periodic movement of the region of the subject; a storage unit that stores the generated image data synchronized with the acquired biosignal data; a biosignal analysis unit that analyzes the biosignal data and detects a specific signal waveform; and a control unit. The control unit: calculates, based on a time difference or a time ratio between multiple consecutive periods obtained from the specific signal waveform detected, a score indicating the stability of the periodic movement among the various periods; causes the biosignal analysis unit to extract a detected period from among the multiple consecutive periods on the basis of the calculated score and a threshold range for the time difference or time ratio; retrieves from the storage unit the image data generated for the extracted period ...

METHOD AND APPARATUS FOR REDUCING IMAGE ARTIFACTS

A method and apparatus are provided for reducing motion related imaging artifacts. The method includes obtaining an image data set of a region of interest in an object, obtaining a motion signal indicative of motion of the region of interest, and determining a displacement and a phase of at least a portion of the motion signal. The method also includes mapping the image data set into a matrix based on the displacement and phase of the motion signal, and generating an image of the region of interest from the matrix.

SYSTEMS AND METHODS FOR CARDIOVASCULAR-DYNAMICS CORRELATED IMAGING

A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient. 1. A method for cardiovascular-dynamics correlated imaging , comprising:receiving a time series of images of at least a portion of a patient;receiving a time series of cardiovascular data for the patient;evaluating correlation between the time series of images and the time series of cardiovascular data;identifying vascularized tissue of the patient based upon the correlation; anddetermining a property of the patient, relating to the vascularized tissue, based upon the correlation.2. (canceled)3. The method of claim 1 , the step of receiving a time series of images comprising receiving a time series of electrical impedance tomography images.45-. (canceled)6. The method of claim 1 , further comprising generating the time series of images as a time series of electrical impedance tomography images.711-. (canceled)12. The method of claim 1 , the step of receiving a time series of cardiovascular data comprising receiving a time series of pulse-oximetry data.1314-. (canceled)15. The method of claim 1 , further comprisinggenerating the time series of images at a first series of times;recording the time ...

Synchronization of ultrasound imaging data with electrical mapping

An image of an electro-anatomical map of a body structure having cyclical motion is overlaid on a 3D ultrasonic image of the structure. The electro-anatomical data and anatomic image data are synchronized by gating both electro-anatomical data acquisition and an anatomic image at a specific point in the motion cycle. Transfer of image data includes identification of a point in the motion cycle at which the 3-dimensional image was captured or is to be displayed.

Respiratory motion compensation for four-dimensional computed tomography imaging using ultrasound

A method for determining a surrogate respiratory signal for four-dimensional computed tomography using ultrasound data includes acquiring computed tomography data with a computed tomography imaging system (402), acquiring ultrasound data with an ultrasound probe of an ultrasound imaging system (404) concurrently with acquiring the computed tomography data during one or more respiratory cycles, wherein the ultrasound probe is aligned to acquire an image of a diaphragm of a subject, synchronizing the acquired computed tomography data and the acquired ultrasound data, and determining a surrogate respiratory signal from the acquired ultrasound data.

VASCULAR FLOW ASSESSMENT

A vascular assessment apparatus is disclosed. The apparatus is configured to receive medical images of a coronary vessel tree of a subject from a medical imaging device and analyze the medical images to identify vessel segments within the coronary vessel tree. For each identified vessel segment, the apparatus is configured to analyze portions of the segment to determine at least one of a radius, diameter, or cross-sectional area of the vessel segment at the analyzed portions, determine resistances for the analyzed portions of the vessel segment based the radius, diameter, or the cross-sectional area at the analyzed portions, and combine the determined resistances for the analyzed portions of the vessel segment to determine a total resistance of the each identified vessel segment and calculate an index indicative of vascular function based on the determined flow rates.

BIOIMPEDANCE SPECTROGRAPHY SYSTEM AND METHOD

A device and method for bioimpedance spectrography is corrected for breathing artefacts. A breathing signal is used in conjunction with the impedance signal to adjust for the time within the respiratory cycle at which the measurements are made. The correction allows the device to characterize tissue parameters accurately with fewer measurement points.

MAGNETIC RESONANCE IMAGING APPARATUS AND IMAGE PROCESSING APPARATUS

A magnetic resonance imaging apparatus according to an embodiment includes a sequence controller and a storage unit. The sequence controller acquires magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject. The storage unit stores therein the magnetic resonance signals acquired at the time phases.

UP-SAMPLING OF SIGNALS BY ANALYTIC PHASE PROJECTION

The systems and methods of the present disclosure address the problem of up-sampling an insufficiently sampled signal of numbers or images that does not yield interpretable data. A computing device may acquire from a sensor, a reference signal and a quasi-periodic signal of a subject over a predefined time period. The reference signal may have a fixed sampling rate. The quasi-periodic signal may have a variable sampling rate. The computing device may filter, using a band-pass filter, the reference signal to obtain a monocomponent signal. The computing device may determine, by applying a Hilbert transform on the monocomponent signal, an analytic phase. The computing device may generate a phase projected signal from the quasi-periodic signal based on the analytic phase. The phase projected signal may have a plurality of data points of the quasi-periodic signal across the predefined time period mapped to a predefined phase interval.

X-ray diagnostic apparatus, image processing apparatus, and program

An X-ray diagnostic apparatus includes an image generating unit (2) which generates a plurality of X-ray images by repeatedly radiographing a subject before and after injection of a contrast medium, a region detecting unit (20) which detects a non-contrast region from a plurality of mask images before injection of the contrast medium and a plurality of contrast images after injection of the contrast medium, which constitute the plurality of X-ray images, a mask selecting unit (19) which separately selects one mask image with respect to each of the contrast images on the basis of a correlation between the contrast image and the mask image upon localization to the non-contrast region, and a subtraction processing unit (21) which generates a subtraction image by performing subtraction between the contrast image and the selected mask image.

MULTI-PHASE CARDIAC IMAGER

A method of cardiac gating for use in an imaging apparatus includes monitoring a patient's cardiac cycle, and determing a cardiac cycle time for the patient. A desired cardiac phase of interest is selected, and a delay from a reference point in the cardiac cycle is determined. The delay is a function of the selected cardiac phase and the cardiac cycle time. Finally, the selected cardiac phase is located in the cardiac cycle using the delay. This cardiac gating method compensates for non-uniform changes in the patient's cardiac cycle corresponding to a non-uniform distribution of cardiac phases in the patient's cardiac cycle.

X-ray diagnostic apparatus, image processing apparatus, and program

SYSTEM FOR FUNCTIONAL MAGNETIC RESONANCE IMAGE DATA ACQUISITION

СПОСОБЫ ОЦЕНКИ СООТВЕТСТВИЯ НОРМЕ БИОЛОГИЧЕСКОЙ ТКАНИ

Группа изобретений относится к медицинской технике, а именно к средствам электромагнитного биозондирования и биовизуализации. Портативная система содержит портативный блок управления, подключенный к блоку управления ручной зонд, распространяющий генерируемое блоком управления электромагнитное поле, при этом зонд можно перемещать вокруг биологического объекта и помещать внутрь объекта, во время работы зонд измеряет создаваемое электромагнитное поле, рассеянное и/или отраженное биологическим объектом, и блок слежения, который фиксирует положение ручного зонда, причем блок слежения является внутренним устройством в портативном блоке управления. Способ оценки функционального и/или патологического состояния биологической ткани содержит генерацию электромагнитного сигнала, при этом данный электромагнитный сигнал является первым сигналом, передачу по меньшей мере части первого сигнала от портативного блока управления на ручной зонд с проводным подключением, излучение посредством ручного зонда ...

РЕТРОСПЕКТИВНАЯ СОРТИРОВКА 4D СТ ПО ФАЗАМ ДЫХАНИЯ НА ОСНОВАНИИ ГЕОМЕТРИЧЕСКОГО АНАЛИЗА ОПОРНЫХ ТОЧЕК ФОРМИРОВАНИЯ ИЗОБРАЖЕНИЯ

... 1. Маркер дыхания (40, 140, 240, 340, 440), содержащий ! распознаваемый участок (42, 342, 442), выполненный таким образом, что он пересекает изображения, полученные в разных позициях вдоль оси (20) сканирования сканера (10) формирования изображения, и распознается как маркирующий признак в изображениях, полученных сканером формирования изображения в разные моменты времени и в разных позициях вдоль оси сканера. ! 2. Маркер дыхания (140, 240) по п.1, дополнительно включающий в себя ! прокладочный участок (144, 244, 245), отделяющий распознаваемый участок (42, 342) от субъекта (18) формирования изображения. ! 3. Маркер дыхания (140, 240) по п.2, в котором прокладочный участок (144, 244, 245) имеет относительно низкую или нулевую видимость в изображениях по сравнению с распознаваемым участком (42). ! 4. Маркер дыхания (40, 140, 240, 340, 440) по п.1, в котором распознаваемый участок (42, 342, 442) является протяженным. ! 5. Маркер дыхания (140, 240) по п.4, дополнительно включающий в себя один ...

УПРАВЛЯЕМОЕ ИМПУЛЬСАМИ ECG ВРЕМЕННОЕ ВЗЯТИЕ ЗАМЕРОВ В КИНЕТИЧЕСКОМ МОДЕЛИРОВАНИИ СЕРДЦА

... 1. Устройство (10) для обнаружения импульсов излучения из интересующей области предмета (14), причем устройство содержит: ! средство (50) наблюдения, которое наблюдает периодические биологические циклы предмета (14); ! детектор (60) точек запуска, который обнаруживает время (t1, t2,..., tn) общей опорной точки (R1, R2,..., Rn) в каждом периодическом цикле предмета (14); ! селектор (62) последовательности, который выбирает последовательность (64) номинальных сегментов взятия замеров (S1, S2,..., Sn), причем каждый номинальный сегмент взятия замеров (S1, S2,..., Sn) имеет время начала (T1, T2,..., Tn) и время конца (T2,..., T(n+1)); и ! процессор (58) синхронизации, который синхронизирует моменты времени начала и остановки каждого номинального сегмента взятия замеров (S1, S2,..., Sn) с моментами времени обнаруженных опорных точек (R1, R2,..., Rn). ! 2. Устройство по п.1, дополнительно включающее в себя: ! сортировщик (66) для сортировки полученных импульсов излучения в наборы данных, собранные ...

КОМПЕНСАЦИЯ ДВИЖЕНИЯ В ФУНКЦИОНАЛЬНОМ ФОРМИРОВАНИИ ИЗОБРАЖЕНИЙ

... 1. Способ формирования диагностического изображения с компенсацией дыхательного и сердечного движения, содержащий: ! генерацию множества изображений сердца в каждой из множества фаз дыхания и сердца с первой модальностью формирования изображения; ! преобразование изображений из множества изображений, которые имеют общую фазу сердца и различные фазы дыхания, в последовательность компенсированных изображений дыхания на множестве фаз сердца и на выбранной общей фазе дыхания; ! преобразование последовательностей компенсированных изображений дыхания согласно форме и модели движения сердца, чтобы генерировать последовательности компенсированных изображений сердца и дыхания в выбранной общей фазе сердца и в выбранной общей фазе дыхания; и ! объединение изображений в выбранных общих фазах сердца и дыхания. ! 2. Способ по п.1, дополнительно содержащий: ! генерацию изображений сердца некоторого субъекта в каждой из множества фаз сердца со второй модальностью формирования изображения; ! подгонку общей ...

ВИЗУАЛИЗАЦИЯ СО СТРОБИРОВАНИЕМ ПО МНОЖЕСТВУ СЕРДЕЧНЫХ ТОНОВ И ПОСТОБРАБОТКА ДАННЫХ ВИЗУАЛИЗАЦИИ НА ОСНОВАНИИ СЕРДЕЧНОГО ТОНА

... 1. Способ, содержащий этапы, на которых:получают данные, показывающие акустические характеристики сердца, в течение сердечных циклов;идентифицируют первый сердечный тон акустических характеристик сердца, соответствующий конечной систоле;формируют конечно-систолический сигнал запуска визуализации на основании идентифицированного первого сердечного тона;проспективно стробируют получение данных по отношению к конечно-систолическому сигналу запуска визуализации, чтобы получить первые данные визуализации сердца, соответствующие первому заданному интервалу получения данных от начала диастолы;идентифицируют второй сердечный тон акустических характеристик сердца, соответствующий конечной диастоле;формируют конечно-диастолический сигнал запуска визуализации на основании идентифицированного второго сердечного тона;проспективно стробируют получение данных по отношению к конечно-диастолическому сигналу запуска визуализации, чтобы получить вторые данные визуализации сердца, соответствующие второму заданному ...

АДАПТАЦИЯ ОКНА РЕКОНСТРУКЦИИ В КОМПЬЮТЕРНОЙ ТОМОГРАФИИ СО СТРОБИРУЕМОЙ ЭЛЕКТРОКАРДИОГРАММОЙ

... 1. Система, содержащая ! компонент (140) управления окнами, который принимает сигнал ЭКГ, содержащий преждевременный сердечный цикл, в котором сигнал ЭКГ синхронизирован во времени с рентгеновскими проекционными данными бьющегося сердца, и в котором компонент (140) управления окнами (140) располагает первое окно реконструкции в пределах первого сердечного цикла, чтобы соответствовать желаемой кардиальной фазе, когда преждевременный сердечный цикл заставляет первое окно реконструкции соответствовать другой кардиальной фазе; и ! устройство (148) реконструкции, которое реконструирует проекционные данные, соответствующие множеству окон реконструкции различных кардиальных циклов, чтобы создать данные изображения, характерные для желаемой фазы биения сердца. ! 2. Система по п.1, в которой компонент (140) управления окнами (140) изменяет положение первого окна реконструкции во времени относительно опорного сигнала в пределах первого сердечного цикла, когда первый временной интервал от опорного ...

OPTISCHER SENSOR ZUR NICHT-INVASIVEN BLUTDRUCKMESSUNG UND KALIBRIERUNGSVERFAHREN

Verfahren und Signalverarbeitungseinheit zur Ermittlung eines kardiogenen Signals

Die Erfindung betrifft ein Verfahren und eine Signalverarbeitungseinheit, um eine Schätzung (Sigres,est) für ein respiratorisches Signal zu ermitteln. Die Signalverarbeitungseinheit empfängt Messwerte von einem Summen-Signal-Sensor und erzeugt ein Summen-Signal (SigSum), welches eine Überlagerung des respiratorischen Signals mit einem kardiogenen Signal ist. Die Signalverarbeitungseinheit detektiert mehrere Herzschläge und jeweils einen Herzschlag-Zeitraum [H_Zr(x)]. Sie berechnet ein Zwischen-Signal (Sigcom), indem sie den Einfluss der Herzaktivität auf das Summen-Signal (SigSum) rechnerisch kompensiert. Die Signalverarbeitungseinheit ermittelt ein Dämpfungs-Signal [Mod(1), ..., Mod(n)], welches ein Maß für den durchschnittlichen zeitlichen Verlauf des Beitrags des kardiogenen Signals am Zwischen-Signal (Sigcom) in einem vorgegebenen Referenz-Herzschlag-Zeitraum (H_Zrref) ist. Sie erzeugt einen Zwischen-Signalabschnitt [SigAcom(x)] als Abschnitt des Zwischen-Signals (Sigcom) in einem Herzschlag-Zeitraum ...

Prolapse detection and tool dislodgement detection

An intracoronary wire, system and method for evaluating intracoronary flow

A coronary wire 10 having: a working length running from a proximal end for connection with a connector to a distal end for insertion through a catheter 11 into a coronary vessel of a patient; a flexible length, a portion of which is exposed, in use, from the catheter and able to make contact with the coronary vessel; a distal tip at the distal end; an electrode 7, 13 on the flexible length at the distal tip or offset from the distal tip by a predetermined spacing; and electrical insulation electrically insulating the exposed portion of the flexible length of the wire except at the electrode at the distal end to allow the electrode to electrically contact the coronary vessel. In another aspect an intracoronary evaluation system 1 and method comprises a coronary wire to provide local intracoronary chamber and vessel data using the wire. The system further comprises a learnt data set comprising intracoronary chamber and vessel data trained against intracoronary flow data. A processor is operable ...

THREE-DIMENSIONAL PHASE CONTRAST MAGNET RESONANCE ILLUSTRATION WITH INTERLOCKED PROJECTION RECONSTRUCTION DATA

Physiological corrections in functional magnetic resonance imaging

Selection of medical images based on image data

METHOD OF MAGNETIC RESONANCE IMAGING

PHOTOACOUSTIC ELECTROCARDIOGRAM-GATED KILOHERTZ VISUALIZATION

In one embodiment, a photoacoustic imaging system receives user input to specify one or more imaging wavelengths, and a target number of image frames to be taken of a target tissue region. The specified imaging wavelengths are set to capture at least two different photoabsorbing molecules in the target tissue. The photoacoustic imaging system takes image frames at the specified wavelengths, while the system also receives ECG and respiration data of the subject. Image frames are discarded based on the respiration data, and the other image frames are sorted into a plurality of slots corresponding to different points of the cardiac cycle from the ECG data. The system creates a composite image from the one or more wavelengths to show the target tissue of interest through the different points of the cardiac cycle.

ARTERY IMAGING SYSTEM

Techniques for imaging a blood vessel are described. A transducer attached to a catheter is guided to a first site within a blood vessel. The catheter is moved to a second site proximal to the first site at a speed selected to enable the transducer to generate a signal indicative of a geometry of the wall, the lumen, and a portion of the side branch. A first image of the blood vessel obtained from the signal is oriented with a second image of the blood vessel such that a first portion of the first image aligns with a second portion of the second image.

Detection of motion in dynamic medical images

UNOBTRUSIVE ACTIVE EYE INTERROGATION

Methods and systems for determining a physiological parameter of a subject through interrogation of an eye of the subject with an optical signal are described. Interrogation is performed unobtrusively. The physiological parameter is determined from a signal sensed from the eye of a subject when the eye of the subject is properly aligned with regard to an interrogation signal source and/or response signal sensor.

METHOD FOR MYOCARDIAL SEGMENT WORK ANALYSIS

The invention relates to medical monitoring apparatuses, methods, and computer programs for determining power or work as a function of time for individual myocardial segments based on strain and pressure measurements. Compared to prior art determinations of determination of mechanical power or work for individual segments, the invention is advantageous as it provides such determination solely from a pressure measurement or estimate and a measurement of strain, preferably by echocardiography, such as speckle tracking ultrasound imaging. This allows a fast, easy and non-invasive determination with high temporal and spatial resolution. A number of indices for segment work can be calculated which can be used as markers for the individual segment function as well as for a selection of patient for CRT.

SYSTEM FOR MONITORING AND PRESENTING HEALTH, WELLNESS AND FITNESS DATA WITH FEEDBACK AND COACHING ENGINE

A nutrition and activity management system is disclosed that monitors energy expenditure of an individual through the use of a body-mounted sensing apparatus. The apparatus is particularly adapted for continuous wear. The system is also adaptable or applicable to measuring a number of other physiological parameters and reporting the same and derivations of such parameters. A weight management embodiment is directed to achieving an optimum or preselected energy balance between calories consumed and energy expended by the user. An adaptable computerized nutritional tracking system is utilized to obtain data regarding food consumed, Relevant and predictive feedback is provided to the user regarding the mutual effect of the user's energy expenditure, food consumption and other measured or derived or manually input physiological contextual parameters upon progress toward said goal.

MULTI-ENERGY X-RAY SOURCE

An apparatus for use in a radiation procedure includes a radiation filter having a first portion and a second portion, the first and the second portions forming a layer for filtering radiation impinging thereon, wherein the first portion is made from a first material having a first x-ray filtering characteristic, and the second portion is made from a second material having a second x-ray filtering characteristic. An apparatus for use in a radiation procedure includes a first target material, a second target material, and an accelerator for accelerating particles towards the first target material and the second target material to generate x-rays at a first energy level and a second energy level, respectively.

MAGNETIC RESONANCE IMAGING WITH RANDOMLY DISTRIBUTED RECORDING OF RAW DATA

In a method and apparatus for recording magnetic resonance (MR) signals from an examination object, raw data space is filled with MR signals in raw data lines. Movement information of the examination object is detected during recording of the MR signals and the movement information is grouped into different movement phases of the examination object. A temporally randomly distributed sequence of the recording of the raw data lines is determined, with which at least one predetermined portion of the raw data space is filled MR signals. The MR signals are acquired in the determined temporally randomly distributed sequence of the raw data lines in the predetermined portion. Each recorded raw data line is allocated to one of the movement phases of the examination object. 1. A method for acquiring magnetic resonance (MR) signals from an examination subject , comprising:operating an MR scanner to acquire MR signals from a subject in said MR scanner and, during acquisition of said MR signals, also acquiring movement information representing movement of the subject during the acquisition of said MR signals;providing said MR signals and said movement information to a processor, and grouping the movement information into different movement phases of the subject;from said processor, entering said MR signals into an electronic memory representing raw data space comprised of a plurality of raw data lines, in order to fill at least a predetermined portion of the raw data space with said MR signals, with said MR signals for the plurality of raw data lines being acquired according to a temporally randomly distributed sequence;in said processor, allocating each raw data line in said predetermined portion to one of said movement phases respectively, thereby generating a data file comprising the raw data space filled with said MR signals acquired according to said temporally randomly distributed sequence; andmaking said data file available at an output of said processor in a form ...

Automatically Determining 3D Catheter Location and Orientation Using 2D Fluoroscopy Only

A method for automatically determining the 3D position and orientation of a radio-opaque medical object in a living body using single-plane fluoroscopy comprising: (a) capturing a stream of digitized 2D images from a single-plane fluoroscope; (b) detecting an image of the medical object in a subset of the digital 2D images; (c) applying to the digital 2D images calculations which preserve original pixel intensity values and permit statistical calculations thereon, using (i) multiple sequential determinations of a midline of the medical object image, (ii) a plurality of unfiltered raw-data cross-sectional intensity profiles perpendicular to each sequentially-determined midline, (iii) removal of outlier profiles from each plurality of profiles, and (iv) statistically combining each plurality of profiles to estimate image dimensions, thereby to measure the medical-object image from a final estimation of image dimensions; (d) applying conical projection and radial elongation corrections to the image measurements; and (e) calculating the 3D position and orientation of the medical object from the corrected 2D image measurements. 1. A method for automatically determining the 3D position and orientation of a radio-opaque medical object in a living body using single-plane fluoroscopy comprising:capturing a stream of digitized 2D images from a single-plane fluoroscope;detecting an image of the medical object in a subset of the digital 2D images; multiple sequential determinations of a midline of the medical object image;', 'a plurality of unfiltered raw-data cross-sectional intensity profiles perpendicular to each sequentially-determined midline;', 'removal of outlier profiles from each plurality of profiles; and', 'statistically combining each plurality of profiles to estimate image dimensions, thereby to measure the medical-object image from a final estimation of image dimensions;, 'applying to the digital 2D images calculations which preserve original pixel intensity ...

Retrospective retrofitting method to generate a continuous glucose concentration profile by exploiting continuous glucose monitoring sensor data and blood glucose measurements

Continuous Glucose Monitoring (CGM) devices provide glucose concentration measurements in the subcutaneous tissue with limited accuracy and precision. Therefore, CGM readings cannot be incorporated in a straightforward manner in outcome metrics of clinical trials e.g. aimed to assess new glycaemic-regulation therapies. To define those outcome metrics, frequent Blood Glucose (BG) reference measurements are still needed, with consequent relevant difficulties in outpatient settings. Here we propose a “retrofitting” algorithm that produces a quasi continuous time BG profile by simultaneously exploiting the high accuracy of available BG references (possibly very sparsely collected) and the high temporal resolution of CGM data (usually noisy and affected by significant bias). The inputs of the algorithm are: a CGM time series; some reference BG measurements; a model of blood to interstitial glucose kinetics; and a model of the deterioration in time of sensor accuracy, together with (if available ...

Photoplethysmography Based Non-Invasive Blood Glucose Prediction by Neural Network

The PPG based NIBG neural network prediction system of the present invention comprises a neural network configured to predict BG level of a subject based on PPG signal obtained from the subject wherein the subject is not undergoing medical treatment and the neural network is trained using training data from subjects not undergoing medical treatment. In another embodiment, the PPG based NIBG neural network prediction system of the present invention predicts BG level of a subject based on HbA1c of the subject measured using conventional finger prick method as well as PPG signal obtained from the subject wherein the subject is not undergoing medical treatment and the neural network is trained using training data from subjects not undergoing medical treatment.

BLOOD FLOW GATED MRI

A magnetic resonance imaging method and apparatus includes a navigator region defined within the subject by selective excitation. Blood flow is measured within the selected region using the principles of phase contrast MR angiography. A cardiac cycle plot is constructed from Fourier transformed data that represents measured velocity of blood flow through the navigator region as a function of time. On the basis of the cardiac cycle plot and the navigator measurements, data acquisition is synchronized or gated to portions of the cardiac cycle.

MEDICAL IMAGE DIAGNOSIS APPARATUS, IMAGE RECONSTRUCTION METHOD, AND COMPUTER-READABLE STORAGE MEDIUM STORING THEREIN IMAGE RECONSTRUCTION PROGRAM

A medical image diagnosis apparatus (1) includes a data obtaining unit (730), a pulse wave information obtaining unit (735), and a reconstructing unit (731). The data obtaining unit (730) obtains scan data generated by scanning an examined subject. The pulse wave information obtaining unit (735) obtains pulse wave information of the examined subject, along with the scan. The reconstructing unit (731) performs image reconstruction corresponding to electrocardiogram synchronization of the examined subject, by using the pulse wave information and the scan data.

РЕТРОСПЕКТИВНАЯ СОРТИРОВКА 4D СТ ПО ФАЗАМ ДЫХАНИЯ НА ОСНОВАНИИ ГЕОМЕТРИЧЕСКОГО АНАЛИЗА ОПОРНЫХ ТОЧЕК ФОРМИРОВАНИЯ ИЗОБРАЖЕНИЯ

Изобретение относится к медицинской диагностике. Устройство сортировки изображения содержит маркер дыхания, содержащий распознаваемый участок, выполненный с возможностью пересечения изображений, полученных в разных позициях вдоль оси сканирования сканера формирования изображения, и распознаваемый как маркирующий признак в изображениях, полученных сканером формирования изображения в разные моменты времени и в разных позициях вдоль оси сканера. Процессор сконфигурирован с возможностью определения положений маркирующих признаков в изображениях и сортировки изображений по фазе дыхания на основании определенных положений маркирующих признаков в изображении. Раскрыты устройство для организации изображений, способ для организации изображений и цифровой носитель, на котором хранятся процессорно-выполняемые инструкции для осуществления способа. Технический результат состоит в обеспечении ретроспективной сортировки изображений на основании фазы дыхания. 4 н. и 17 з.п. ф-лы, 8 ил.

СИСТЕМА ПОЛУЧЕНИЯ ИЗОБРАЖЕНИЯ С КАРДИО- И/ИЛИ ДЫХАТЕЛЬНОЙ СИНХРОНИЗАЦИЕЙ И СПОСОБ 2-МЕРНОЙ ВИЗУАЛИЗАЦИИ В РЕАЛЬНОМ ВРЕМЕНИ С ДОПОЛНЕНИЕМ ВИРТУАЛЬНЫМИ АНАТОМИЧЕСКИМИ СТРУКТУРАМИ ВО ВРЕМЯ ПРОЦЕДУР ИНТЕРВЕНЦИОННОЙ АБЛЯЦИИ ИЛИ УСТАНОВКИ КАРДИОСТИМУЛЯТОРА

... 1. Система обработки изображений, функционирующая в рабочей станции, связанной с системой получения изображений, при этом, упомянутая система получения изображений выполнена с возможностью выполнения способа получения изображений для отслеживания направляемых движений инвазивного инструмента, при проведении по анатомическим структурам сердечно-сосудистой системы и/или камер сердца пациента, посредством интраоперационного получения и записи последовательности 2-мерных динамических изображений с одного и того же угла проекции и расстояния до объекта, причем, упомянутые изображения представляют инвазивный инструмент во время разных стадий упомянутого направляемого движения, причем система (5) обработки изображений запрограммирована для- записи конкретных фаз сердечного и/или дыхательного циклов пациента для каждого пути, во время получения и записи 2-мерных флюорограмм,- выбора набора таких изображений, которые соответствуют предварительно определяемой конкретной фазе сердечного и/или дыхательного ...

COMPUTERTOMOGRAPHIE-BILDGEBUNG

BLUTSTRÖMUNGS-GATE-MRI

VERFAHREN UND SYSTEM FÜR PRÄDIKTIVES PHYSIOLOGISCHES GATING

A method and apparatus for controlling the generation of a magnetic resonance imaging sequence

ECG MORE STEERED TEMP-ORAL SCANNING WITH KARDIALER KINETIC MODELLING

MODEL-BASED DETERMINATION OF THE CONTRACTION STATUS OF A PERIODICALLY CONTRACTED OBJECT

MEDICAL SOUND SENSOR

SELECTION OF MEDICAL PICTURES DUE TO GRAPHIC DATA

Automatically determining 3D catheter location and orientation using 2D fluoroscopy only

A method for automatically determining the 3D position and orientation of a radio-opaque medical object in a living body using single-plane fluoroscopy comprising capturing a stream of digitized 2D images from a single-plane fluoroscope (10), detecting the image of the medical object in a subset of the digital 2D images, applying pixel-level geometric calculations to measure the medical-object image, applying conical projection and radial elongation corrections (31) to the image measurements, and calculating the 3D position and orientation of the medical object from the corrected 2D image measurements.

OPTICAL NONINVASIVE BLOOD PRESSURE SENSOR AND METHOD

A blood pressure sensor (12) includes a source of photo-radiation, such as an array (30) of laser diodes (30A-I). The sensor also includes a two- dimensional, flexible reflective surface (14). The reflective surface is nominally positioned relative to the radiation source such that the radiation travels in a direction normal to the reflective surface. The reflective surface is placed adjacent to the location on the patient where the blood pressure data is to be acquired. Radiation from the source is reflected off of the reflective surface onto a two-dimensional array (17) of photo-detectors (18). Systolic and diastolic blood pressure fluctuations in the patient are translated into deflections of the patient's skin. These deflections cause corresponding deflections in the two dimensional reflective surface. The associated movement of said flexible reflective surface (14) due to blood pulsation causes scattering patterns from said reflective surface to be detected by the two dimensional array ...

LIFE LOG UTILIZATION SYSTEM, LIFE LOG UTILIZATION METHOD, AND RECORDING MEDIUM

Highly reliable ingestible event markers and methods for using the same

SURGICAL DATA MONITORING AND DISPLAY SYSTEM

A surgical data monitoring and display system is described. In some embodiments, the system includes a data storage module that stores retrospective data and real-time surgical data concerning a patient, a first processing module that receives and processes the retrospective data into processed retrospective data, and a second processing module that receives and processes the real-time data into processed real-time data. Each of the first processing module and the second processing module transmits their processed data to first and second display modules, respectively, before or during performance by a healthcare provider of a medical or surgical procedure on the patient.

ULTRASONIC DIAGNOSIS APPARATUS

An ultrasonic diagnosis apparatus characterized in that previously picked up three-dimensional image data on a subject from which a reference image is clipped is recorded at least over one period of a periodically acting internal organ of the subject, while attaching time phase information on a biological signal of the subject to produce time-series volume data (14, 15) consisting of a two-dimensional image data group, and the two-dimensional image data to which time phase information corresponding to the time phase information on the biological signal of the subject at the time of picking up an ultrasonic image is attached is extracted from the three-dimensional image data, thus clipping the reference image.

CARDIAC GATING METHOD AND SYSTEM

The invention provides new materials and devices for EKG gating and defibrillation that alleviate problems in the art. Embodiments of the invention utilize special electrodes (120,130) of certain dimensions and made form materials that can generate trigger signals or transmit pulses more reliably and/or with less interference to other diagnostic procedures. The electrodes (120,130) and systems improve the amplitude and overall reliability of detecting EKG signals. The improved signals enable more reliable detection of a true cardiac phase and improved cardiac gating. Thus, embodiments of the invention lead to improved image quality, more accurate imaging of cardiac and intrathoracic/upper abdominal structures and improved referencing of systemic arterial blood flow for blood flow measurement within the chest and elsewhere in the body, including, for example, the extremities.

SYSTEM AND METHOD FOR A NON-INVASIVE MEDICAL SENSOR

Method for determining an optimal trigger time and device for ECG-triggered recording of an object

There is described a method for determining an optimal trigger time for an ECG-triggered recording of an object. In this respect, a time sequence of dynamic images is firstly acquired with simultaneous recording of an ECG signal, then a time in the cardiac cycle is assigned to each dynamic image, and finally the dynamic images are analyzed, for example by calculation of a degree of similarity, in order to identify the time of minimal movement of the object within the time sequence.

Method and apparatus for obtaining a volumetric scan of a periodically moving object

Method and apparatus for acquiring and processing a volumetric scan of a periodically moving object. A volumetric scan is performed of the periodically moving object which repeats a cycle of movement over time. A time interval of the periodic movement of the object is identified within the volumetric scan, and the volumetric scan is rearranged based on the time interval.

Prolapse detection and tool dislodgement detection

A tool dislodgement detection apparatus includes an MPS outputting position and orientation (P&O) readings for determining tool motion. A control generates an alarm based on the tool motion and dislodgement criteria. The criteria includes whether the tool motion meets a condition based on the type of medical procedure or tool, the tool parking position, a patient characteristic (e.g., age, weight, gender) or a physician preference. The criteria includes when the correlation between the tool motion and the cardiac, respiration and patient motion changes abruptly. In a prolapse detection apparatus, guidewire tip P&O readings determine a tip motion vector. The control generates an alarm using the motion vector and predetermined criteria. The criteria include a substantial change in the tip orientation not accompanied by a corresponding position change and a change in the motion vector by about 180° accompanied by a corresponding position change no greater than a threshold.

Method and device for magnetic resonance imaging data acquisition guided by physiologic feedback

An adaptive real-time radial k-space sampling trajectory (ARKS) can respond to a physiologic feedback signal to reduce motion effects and ensure sampling uniformity. In this adaptive k-space sampling strategy, the most recent signals from an ECG waveform can be continuously matched to the previous signal history, new radial k-space locations were determined, and these MR signals combined using multi-shot or single-shot radial acquisition schemes. The disclosed methods allow for improved MRI imaging.

CARDIAC GATING METHOD AND SYSTEM

The invention provides new materials and devices for EKG gating and defibrillation that alleviate problems in the art. Embodiments of the invention utilize special electrodes (120,130) of certain dimensions and made form materials that can generate trigger signals or transmit pulses more reliably and/or with less interference to other diagnostic procedures. The electrodes (120,130) and systems improve the amplitude and overall reliability of detecting EKG signals. The improved signals enable more reliable detection of a true cardiac phase and improved cardiac gating. Thus, embodiments of the invention lead to improved image quality, more accurate imaging of cardiac and intrathoracic/upper abdominal structures and improved referencing of systemic arterial blood flow for blood flow measurement within the chest and elsewhere in the body, including, for example, the extremities.

STAGED RECONSTRUCTION OF PLANNING IMAGES FOR CARDIAC MAGNETIC RESONANCE IMAGING

Disclosed herein is a medical system (100, 300, 700) comprising a magnetic resonance imaging system (102) configured to acquire lines of k-space (144) data from a thoracic region (122) of a subject (118). Execution of machine executable instructions (140) causes a computational system (132) to: repeatedly (200) acquire the lines of k-space data by controlling the magnetic resonance imaging system with the pulse sequence commands; repeatedly (202) assemble motion resolved k-space data (146) from the lines of k-space data using at least one cardiac phase and one respiratory phase of the subject as the k-space data is acquired; retrieve (204) at least a portion (148) of the motion resolved k-space data during acquisition of the k-space data; and construct (206) a preliminary three-dimensional cardiac image (150) using at least a portion of the motion resolved k-space data before acquisition of the lines of k-space data is finished. The pulse sequence commands are according to a three-dimensional ...

AN INTRACORONARY WIRE AND SYSTEM FOR EVALUATING INTRACORONARY FLOW

СИСТЕМА ПОЛУЧЕНИЯ ИЗОБРАЖЕНИЙ С КАРДИО-И/ИЛИ ДЫХАТЕЛЬНОЙ СИНХРОНИЗАЦИЕЙ И СПОСОБ 2-МЕРНОЙ ВИЗУАЛИЗАЦИИ В РЕАЛЬНОМ ВРЕМЕНИ С ДОПОЛНЕНИЕМ ВИРТУАЛЬНЫМИ АНАТОМИЧЕСКИМИ СТРУКТУРАМИ ВО ВРЕМЯ ПРОЦЕДУР ИНТЕРВЕНЦИОННОЙ АБЛЯЦИИ ИЛИ УСТАНОВКИ КАРДИОСТИМУЛЯТОРА

Изобретение относится к области электрофизиологии сердца и, в частности, к процедурам радиочастотной абляции и установки кардиостимуляторов под визуальным контролем. Система обработки изображений, функционирующая в рабочей станции, снабженной также машиночитаемым носителем, выполнена с возможностью интраоперационного получения и записи последовательности 2-мерных флюорограмм с одного и того же угла проекции и расстояния до объекта, записи фаз сердечного и/или дыхательного циклов пациента, во время получения и записи 2-мерных флюорограмм, выбора набора таких 2-мерных флюорограмм, которые соответствуют конкретной фазе сердечного и/или дыхательного циклов пациента, посредством кардио- и/или дыхательной синхронизации, формирования 2-мерной реконструкции анатомических структур сердечно-сосудистой системы и/или камер сердца пациента посредством объединения наложенного поднабора 2-мерных положений инвазивного инструмента на 2-мерных флюорограммах на разных стадиях направляемого движения и отображения ...

УСТРОЙСТВО И СПОСОБ ОТСЛЕЖИВАНИЯ ОСНОВНЫХ ПОКАЗАТЕЛЕЙ СОСТОЯНИЯ ОРГАНИЗМА

... 1. Устройство (1) для отслеживания основных показателей состояния организма субъекта, содержащее:модуль (2) формирования изображения, предназначенный для дистанционного получения данных (3) изображения упомянутого субъекта,интерфейс (7) для приема данных (8) движения упомянутого субъекта и/или упомянутого модуля (2) формирования изображения, при этом упомянутый интерфейс (7) выполнен с возможностью принимать упомянутые данные движения упомянутого субъекта из устройства (10) для фитнеса,модуль (4) обработки, предназначенный для выделения основных показателей (9) состояния организма упомянутого субъекта из упомянутых данных (3) изображения, имодуль (5) управления, предназначенный для адаптации параметров (6a, 6b) упомянутого модуля (2) формирования изображения и/или упомянутого модуля (7) обработки на основе принятых данных (8) движения.2. Устройство (1) по п. 1, в котором упомянутые данные (8) движения включают в себя, по меньшей мере, один из типа движения, направления движения, пути движения ...

Vorrichtung zum Gewinnen eines Volumenscans eines sich periodisch bewegenden Objekts

Vorrichtung zum Akquirieren eines Volumenscans eines sich periodisch bewegenden Objekts, zu der gehören: ein Transducer, der ein Array von Elementen enthält, das dazu dient, Ultraschallsignale in Richtung eines interessierenden Bereichs, der ein sich periodisch bewegendes Objekt enthält, abzustrahlen und von diesem Bereich zu empfangen; ein Sender zum Treiben des Arrays von Elementen, um das sich periodisch bewegende Objekt einmal in einer einzelnen Richtung zu scannen; ein Empfänger zum Empfangen der Ultraschallsignale, wobei die Ultraschallsignale eine Serie benachbarter Scanebenen umfassen; ein Arbeitsspeicher zum Speichern der Serie benachbarter Scanebenen als einen volumetrischen Datensatz; und ein Prozessor zum Verarbeiten der Serie benachbarter Scanebenen, wobei der Prozessor basierend auf dem sich periodisch bewegenden Objekt ein Zeitintervall identifiziert und die Serie benachbarter Scanebenen basierend auf dem Zeitintervall umgruppiert.

Verfahren und Anordnung zur Bestimmung der Position eines medizinischen Instruments

Prolapse detection and tool dislodgement detection

Monitoring physiology

PROCEDURE AND SYSTEM FOR PRÄDIKTIVES PHYSIOLOGICAL GATING

SYNCHRONIZATION OF ULTRASONIC GRAPHIC DATA WITH ELECTRICAL ILLUSTRATION

Algorithmic approach for estimation of respiration and heart rates

One or more aspects of the disclosure relate to monitoring a resting subject's respiration and heart rate through an impulse radio ultra-wideband (IR-UWB) radar in a noninvasive fashion, in order to infer the corresponding health status including heart rate and respiration rate. Any other reflectance technology may be used. These two cardiopulmonary vital signs are derived based on the processing of recorded waveforms that are collected by the IR-UWB radar or any other reflectance technology system, after getting reflected-off the resting subject's body or relevant body part. A novel algorithm that processes the recorded waveforms is proposed to extract these vitals' signals and, accordingly, estimate their rates. This algorithm includes at least three major stages: i) noise reduction, ii) respiration rate estimation, and iii) heart rate estimation. Furthermore, the algorithm addresses the effects of harmonics and intermodulation between the breathing and heartbeat signals without requiring ...

APPARATUS FOR MONITORING CHF PATIENTS USING BIO-IMPEDANCE TECHNIQUE

An apparatus and method for making corrected impedance images of the chest includes an impedance imaging data acquisition system (609,611) which acquires impedance imaging data of the chest, an electrocardiograph (618) which obtains electrocardiograph data of the patient, and a data analyzer (616) which analyzes the electrocardiograph data to obtain information about breathing parameters at the time the impedance imaging data was acquired. The data analyzer reconstructs, from the imaging data and the information about breathing parameters, at least one impedance image of the chest with reduced sensitivity to breathing parameters.

CARDIAC GATING METHOD AND SYSTEM

The invention provides new materials and devices for EKG gating and defibrillation that alleviate problems in the art. Embodiments of the invention utilize special electrodes (120,130) of certain dimensions and made form materials that can generate trigger signals or transmit pulses more reliably and/or with less interference to other diagnostic procedures. The electrodes (120,130) and systems improve the amplitude and overall reliability of detecting EKG signals. The improved signals enable more reliable detection of a true cardiac phase and improved cardiac gating. Thus, embodiments of the invention lead to improved image quality, more accurate imaging of cardiac and intrathoracic/upper abdominal structures and improved referencing of systemic arterial blood flow for blood flow measurement within the chest and elsewhere in the body, including, for example, the extremities.

RETROSPECTIVE SORTING OF 4D CT INTO BREATHING PHASES BASED ON GEOMETRIC ANALYSIS OF IMAGING FIDUCIALS

A respiratory marker (40, 140, 240, 340, 440) includes an elongated detectable portion (42, 342, 442) that is operatively coupled with respiration of an imaging subject such that the elongated detectable portion moves with the respiration. The elongated detectable portion is arranged to intersect images acquired by an imaging scanner (10) at different times and at different positions along a scanner axis (20), and is detectable as a marker feature in the images. A marker position finder (52, 54) is configured to determine positions of the marker features in the images.

METHOD TO CONFIRM MOVEMENT INFORMATION ITEM DESCRIBING MOVEMENT IN AT LEAST PARTIALLY MOVED INSPECTION AREA, AND MAGNETIC RESONANCE DEVICE

The present invention relates to a method to confirm a movement information item describing a movement in an inspection area at least partially moved and a magnetic resonance device, capable of confirming at least one movement information item (25, 26) describing a partial movement of the whole movement, which is discovered in an inspection area at least partially moved. At least one excitation signal (10) with a first frequency band is outputted, and reception signals (16), generated by the excitation signal (10), are recorded by using a reception coil arrangement (3), including a plurality of reception channels, especially, the reception coil arrangement (3) of a magnetic resonance device (1). Coils (4, 5, 6, 7) of the reception coil arrangement (3) are designed to record a reception frequency band including the first frequency band. To confirm the movement information (25, 26), complex reception signals (16) of the reception channels are combined simultaneously in accordance with combination ...

가속도계를 갖는 펄스 옥시미터

... 다양한 실시형태들의 시스템들, 방법들, 및 디바이스들은 가속도계로부터의 판독치들에 기초하여 혈액 산소 판독치들을 취할 수 있는 펄스 옥시미터를 제공한다. 다양한 실시형태들은, 프로세서에 연결된 펄스 옥시미터 및 가속도계를 포함하는 전자적 패치를 제공할 수도 있고, 여기서, 프로세서는 가속도계로부터 수신된 데이터에 적어도 부분적으로 기초하여 펄스 옥시미터의 동작을 제어하도록 프로세서 실행가능 명령들로 구성된다. 다양한 실시형태들에서, 전자적 패치는 펄스 옥시미터에 전력을 공급할 수도 있는 코인 셀 배터리, 또는 다른 저 전력 소스를 더 포함할 수도 있다.

USE OF ULTRASOUND IN THE DIAGNOSIS AND TREATMENT OF MULTIPLE SCLEROSIS

MR-PET CYCLIC MOTION GATING AND CORRECTION

In preparation for acquiring PET image data, subject motion models are built based on physiologic signal monitoring and MR data is collected and used for improved PET imaging. The physiologic signal monitoring is also used during PET imaging, and the acquired MR data is used for prospective or retrospective gating of the PET image acquisition, or in the PET reconstruction for improved correction/imaging.

CALCULATING A FRACTIONAL FLOW RESERVE

A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.

SIGNAL PROCESSING UNIT FOR PRODUCING IMAGES

An exemplary embodiment of the invention provides a signal processing unit for producing images of an object under examination based on data signals of a tomography system, the signal processing unit comprising a processor and an input interface, wherein the input interface is adapted to receive measured data signals. Furthermore, the processor is adapted to generate a pulmonary gating signal based on said measured data signals and is further adapted to generate an image based on said measured data signals by using the pulmonary gating signal.

SINGLE-CAMERA TRACKING OF AN OBJECT

A method and system for determining the position and orientation of an object is disclosed. A set of markers attached or associated with the object is optically tracked and geometric translation is performed to use the coordinates of the set of markers to determine the location and orientation of their associated object.

SYSTEM AND METHOD FOR PROCESSING A SERIES OF IMAGE FRAMES REPRESENTING A CARDIAC CYCLE

The invention relates to a system for processing a series of image frames representing a cardiac cycle, at least comprising input or data collection means for collecting the series of image frames, a memory inter alia for storing and retrieving said series of image frames, a processor for processing the frames, and display means, whereby in use the processor processes the frames to identify from said series of images a frame or frames representing a pre-determined phase of the cardiac cycle whereby the processor compares images from said series of image frames and establishes a measure of identity between such frames, whereby the processor applies said measure of identify to identify the phase of the cardiac cycle pertaining to such frames.

MAGNETIC RESONANCE IMAGING METHOD AND APPARATUS

Upon each data measurement after RF excitation pulse application for spread emphasis imaging, a body movement navigation echo is measured, so that one of them is used as a reference navigation echo. The reference navigation echo and the other navigation echoes are subjected to 1-dimensional Fourier transform in the lead-out direction and a 1-dimensional phase inclination is calculated from these data. The 1-dimensional phase inclination of the reference navigation echo is compared to that of the other navigation echoes, so as to determine whether the difference is within an allowable value. When the difference exceeds the allowable value, the echo signal corresponding to the navigation echo is decided not to be acceptable for correction by the navigation body movement correction method and not used for image re-construction. Measurement is again performed and an image is formed by using an echo signal measured with a navigation echo below the allowable value. Thus, the body movement component ...

Methods, apparatuses, and systems useful in conducting image guided interventions

Methods, apparatuses, and systems relating to image guided interventions on dynamic tissue. One embodiment is a method that includes creating a dataset that includes images, one of the images depicting a non-tissue internal reference marker, being linked to non-tissue internal reference marker positional information, and being at least 2-dimensional. Another embodiment is a method that includes receiving a position of an instrument reference marker coupled to an instrument; transforming the position into image space using a position of a non-tissue internal reference marker implanted in a patient; and superimposing a representation of the instrument on an image in which the non-tissue internal reference marker appears. Computer readable media that include machine readable instructions for carrying out the steps of the disclosed methods. Apparatuses, such as integrated circuits, configured to carry out the steps of the disclosed methods. Systems that include devices configured to carry out ...

Automatic quantitative vessel analysis

Apparatus and methods are described for use with an image of blood vessels of a subject. In response to a user designating a single point on the image (a) a target portion of a blood vessel is automatically identified in the vicinity of the designated point, and (b) quantitative vessel analysis is performed on the target portion of the blood vessel. An output is generated based upon the quantitative vessel analysis. Other embodiments are also described.

System and method for accelerated focused ultrasound imaging

Embodiments of the present invention relate to systems and methods for magnetic resonance imaging (MRI) and, more particularly, to cardiac cine MRI in which the cardiac sequences are gated retrospectively. In some embodiments, UNFOLD or related temporally- based imaging (e.g., UNFOLD-SENSE) is combined with retrospective gating to produce, for example, better images of the heart in the late diastolic part of the cardiac cycle.

Magnetic resonance imaging for therapy planning

Magnetic resonance imaging (MRI) is used for therapy planning. The motion or position of the treatment region is tracked over time for many cycles using MRI. For temporal resolution, the tracking is done in planes through the tumor at different orientations rather than using three-dimensional scanning. The tracking may be used for calculating a spatial probability density function for the target. Alternatively or additionally, spatiotemporal information derived from the surrogate is compared directly to that from the tracked object to determine the accuracy or robustness of the surrogate-to-target 3D correlation Gating or tracking based on this surrogate may be performed where the comparison indicates that the surrogate is sufficiently reliable (accurate).

Heart Treatment Kit, System, and Method for Radiosurgically Alleviating Arrhythmia

Radiosurgical treatments of tissues of the heart mitigate arrhythmias and treat other tumerous and non-tumerous disease using an implanted fiducial positioned in or near the heart using cardiac catheterization techniques. The fiducials may be implanted after diagnostic and planning images of the target tissues have been acquired. Fiducial implantation may take place the day of a scheduled radiosurgical treatment. Techniques to accommodate post-planning fiducial implantation may include registration of the implanted fiducial location with the treatment plan, and active fiducials may limit collateral imaging radiation exposure while enhancing tracking accuracy.

System for Coregistration of Optical Coherence Tomography and Angiographic X-ray Image Data

A system comprises a catheter including a lens, for acquiring optical coherence tomography images within the vessel of interest as the catheter is being retracted from the vessel in the presence of contrast agent. An X-ray imaging system interface receives a first set of X-ray images of an anatomical region including the vessel of interest containing the catheter. The first set of X-ray images are acquired at points corresponding to the particular points within a heart cycle, while the catheter is stationary in the vessel, in response to a heart electrical activity representative signal and in the absence of contrast agent. An image data processor associates the received X-ray images and corresponding optical coherence tomography image data derived at corresponding time points within respective acquisition heart cycles.

Adaptive ECG Trigger Signal Jitter detection for Imaging

A system provides an image acquisition trigger signal compensated for signal processing time delay. An interface receives waveform signal data representing electrical activity of a patient heart over at least one heart beat cycle. A detector detects a particular point associated with a particular signal portion within successive heart beat cycles of the signal data. A first time variation detector provides a first timing adjustment signal in response to detected change in time of occurrence of the detected particular point. A second time variation detector provides a second timing adjustment signal in response to comparison of relative timing of the trigger signal and the detected particular point. An output processor generates the trigger signal in response to the detected particular point and the first timing adjustment signal and the second timing adjustment signal. 1. A system for providing an image acquisition trigger signal compensated for signal processing time delay , comprising:an interface for receiving waveform signal data representing electrical activity of a patient heart over at least one heart beat cycle;a detector for detecting a particular point associated with a particular signal portion within successive heart beat cycles of said signal data;a first time variation detector for providing a first timing adjustment signal in response to detected change in time of occurrence of the detected particular point in said successive heart beat cycles;a second time variation detector for providing a second timing adjustment signal in response to comparison of relative timing of said trigger signal and said detected particular point in at least one of said successive heart beat cycles; andan output processor for generating said trigger signal in response to said first timing adjustment signal and said second timing adjustment signal.2. A system according to claim 1 , includinga third time variation detector for providing a third timing adjustment signal in ...

Automatic reduction of interfering elements from an image stream of a moving organ

Apparatus and methods are described for imaging a portion of a body of a subject that undergoes a motion cycle. A plurality of image frames of the portion are acquired. The image frames are enhanced with respect to a first given feature of the image frames, by (a) image tracking the image frames with respect to the first given feature, (b) identifying a second given feature in each of the image frames, and (c) in response to the identifying, reducing visibility of the second given feature in the image frames. The image frames that (a) have been image tracked with respect to the first given feature, and (b) have had reduced therein the visibility of the second given feature, are displayed as a stream of image frames. Other embodiments are also described.

METHOD AND SYSTEM FOR ELECTROMAGNETIC TRACKING WITH MAGNETIC TRACKERS FOR RESPIRATORY MONITORING

A method and system using electromagnetic tracking to monitor the respiration of a patient. The system includes trackers attached to the patient that emit and receive a magnetic field that changes as the patient breathes. The changing field received by the tracker can be associated with the breathing states of the patient and used to generate a respiratory signal. The respiratory signal may be used to indicate when to advance an intervention tool during an intervention procedure on the patient. The same electromagnetic system may also be used to track the position of the intervention tool, further assisting the intervention procedure. 1. An electromagnetic tracking system , comprising:a first tracker attached to a subject, wherein the first tracker comprises an emitter to emit a magnetic field;a second tracker attached to the subject, wherein the second tracker comprises a first receiver to measure the magnetic field; andlogic to determine a position of the second tracker relative to the first tracker based on the magnetic field measured by the first receiver and to generate a respiratory signal based on the position of the second tracker relative to the first tracker;wherein the position of the second tracker relative to the first tracker changes during a plurality of respiratory states of the subject.2. The system of claim 1 , wherein the emitter comprises at least two emitting coils.3. The system of claim 1 , wherein the first receiver comprises at least two receiving coils.4. The system of claim 1 , wherein the first receiver comprises at least three receiving coils.5. The system of claim 1 , further comprising:a third tracker attached to the subject, wherein the third tracker comprises a second receiver to measure the magnetic field; andlogic to determine a position of the third tracker relative to the first tracker based on the magnetic field measured by the second receiver and to generate the respiratory signal based on the position of the third tracker ...

APPARATUS, SYSTEM AND METHOD FOR VISUALIZING A PERIODICALLY MOVING ANATOMY

The invention relates to an apparatus, a system and a method for visualizing measurement signals of a periodically moving anatomy. A processor receives temporal measurement signals comprising temporal information on the movement of a distal portion of an interventional device within the anatomy, and temporal information of the periodically moving anatomy. It is ascertained whether the temporal information on the movement of the distal portion of the interventional device within the anatomy are aperiodic or periodic. Based on whether the signals are ascertained aperiodic or periodic, the processor outputs to a display the temporal information of the periodically moving anatomy as received in real-time or as gated according to a predetermined phase of a measured or ascertained period. 1. Apparatus for visualizing measurement information of a periodically moving anatomy , wherein the apparatus comprises a processor configured to: ascertain whether the temporal information on the movement of the distal portion of the interventional device is periodic or aperiodic;', 'gate the temporal information of the periodically moving anatomy when periodicity is ascertained;', 'output the temporal information of the periodically moving anatomy as received when the temporal information on the movement of the distal portion of the interventional device is ascertained aperiodic, and', 'output gated temporal information of the periodically moving anatomy when the temporal information on the movement of the distal portion of the interventional device is ascertained periodic., 'receive temporal measurement signals comprising temporal information on the movement of a distal portion of an interventional device and temporal information of the periodically moving anatomy;'}2. A system for visualizing information of a periodically moving anatomy , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'an apparatus according to ;'}the interventional device; anda display configured to ...

LIFE LOG UTILIZATION SYSTEM, LIFE LOG UTILIZATION METHOD, AND RECORDING MEDIUM

A life log utilization system associates event information, emotion information, and behavior information, which are acquired at the same time or within a predetermined time period, records the associated information as a life log of a target person or a user, and outputs the life log or information, such as analysis data and analysis content, generated from the life log as personality analysis information. 1. A life log utilization system comprising:an event information acquisition unit configured to acquire event information in relation to an event occurring in a vicinity of a target person or in relation to an event involving the target person;an emotion information acquisition unit configured to acquire emotion information indicative of an emotional state of the target person;a behavior information acquisition unit configured to acquire behavior information indicative of a behavior of the target person;a life log recording unit configured to associate the event information acquired by the event information acquisition unit, the emotion information acquired by the emotion information acquisition unit, and the behavior information acquired by the behavior information acquisition unit, which are acquired at a same time or within a predetermined time period, and to record the associated information as a life log of the target person; andan analysis information output unit configured to output the life log recorded by the life log recording unit or information generated from the life log as personality analysis information.2. The life log utilization system according to claim 1 , further comprising:a biometric information acquisition unit configured to acquire biometric information indicative of biological activity of the target person;wherein the emotion information acquisition unit acquires the emotion information, based on the biometric information acquired by the biometric information acquisition unit.3. The life log utilization system according to claim 1 , ...

IDENTIFICATION AN DPRESENTATION OF DEVICE-TOVESSEL RELATIVE MOTION

Apparatus and methods are described for use with a tool that is inserted into a portion of a body of a subject that undergoes cyclic motion. The apparatus and methods include using an imaging device, acquiring a plurality of images of the tool inside the portion of the body, at respective phases of the cyclic motion. Using at least one computer processor, an extent of movement of the tool with respect to the portion of the body that is due to the cyclic motion of the portion of the body is determined. In response thereto, an output is generated that is indicative of the determined extent of the movement of the tool with respect to the portion of the body. Other applications are also described. 1. An apparatus , comprising: receive an extraluminal image of a body lumen obtained by the extraluminal imaging device;', 'identify, within the extraluminal image, an endoluminal medical device positioned inside the body lumen;', 'automatically calculate a dimension based on identifying the endoluminal medical device within the extraluminal image, wherein the dimension comprises at least one of a value of the endoluminal medical device or a value of the body lumen associated with deployment of the endoluminal medical device; and', the extraluminal image; and', 'the dimension., 'output, a display in communication with the computer processor, a screen display comprising], 'a computer processor configured for communication with an extraluminal imaging device, wherein the computer processor is configured to2. The apparatus of claim 1 , wherein the computer processor is configured to automatically calculate the dimension based on a known dimension of a tool positioned inside the body lumen.3. The apparatus of claim 1 , wherein the tool comprises a guiding catheter claim 1 , and wherein the known dimension comprises a diameter of the guiding catheter.4. The apparatus of claim 1 , wherein the computer processor is configured to automatically calculate the dimension in response to ...

DEVICE AND METHOD FOR MONITORING VITAL SIGNS

The present invention relates to a device () and method for monitoring vital signs of a subject. In particular, the device for monitoring vital signs () comprises an imaging unit () for obtaining image data () of said subject, an interface () for receiving motion data () of said subject and/or said imaging unit (), a processing unit () for extracting vital signs () of said subject from said image data (), and a control unit () for adapting parameters () of said imaging unit () and/or said processing unit () based on the received motion data (). A further aspect of the invention relates to a fitness device () comprising a device for monitoring vital signs () and a motion detection unit () for providing said device for monitoring vital signs () with motion data (). 1. A device for monitoring vital signs of a subject , comprising:an imaging unit for remotely obtaining image data of said subject,an interface for receiving motion data of said subject, wherein said interface is configured to receive said motion data of said subject from a fitness device,a processing unit for extracting vital signs of said subject from said image data, anda control unit for adapting parameters of said imaging unit or said processing unit based on the received motion data.2. (canceled)3. The device according to claim 1 , wherein said motion data includes at least one of a type of motion claim 1 , a motion direction claim 1 , a motion path claim 1 , a motion amplitude claim 1 , a motion frequency claim 1 , a motion intensity claim 1 , a resistance and force the subject has to work against.4. The device according to claim 1 , wherein said motion data includes physical or workout information about the subject whose vital signs are to be measured.5. The device according to claim 1 , wherein said control unit is configured to adapt the parameters of said processing unit to an expected value range for vital signs based on the received motion data.6. The device according to claim 1 , wherein said ...

ARTIFACT AS A FEATURE IN NEURO DIAGNOSTICS

A multi-modal physiological assessment device and method enables the simultaneous recording and then subsequent analysis of multiple data streams of biological signal measurements to assess the health and function of the brain. Means and methods are provided to identify and leverage artifact samples within ID and 2D bio signal data streams to help create more accurate predictors and classifiers of brain health states and conditions. One sensor's data is used to gate the relevant portion of another bio sensor's data in order to reduce the noise and increase the signal-to-noise ratio. This is a form of phase locking for multimodal data streams for brain health assessment. 1. An analysis method for pre-processing biological sensor data from one of a plurality of concurrently collected independent biological sensor data streams , comprising:identifying and flagging areas of artifact in said one biological sensor data stream; andanalytically characterizing features of the artifact as candidate predictor variables for predictive statistical models for analysis of said plurality of biological sensor data streams.2. An analysis method as in claim 1 , wherein said areas of artifact are used as time markers for analysis of said biological sensor data streams.3. An analysis method as in claim 1 , wherein a flagged artifact in said one biological sensor data stream is used to temporally gate data from another biological sensor data stream.4. An analysis method as in claim 1 , wherein the flagged artifact results from a manual action of a patient during a neuropsychiatric claim 1 , neuropsychological claim 1 , or cognition test.5. An analysis method as in claim 4 , wherein the manual action of the patient comprises clicks on one or more buttons or key strokes on one or more keys of a keyboard to mark times at the beginning and end of a time frame or period of interest.6. An analysis method as in claim 1 , wherein the artifact is automatically flagged without patient input.7. An ...

Apparatus and methods for reducing visibility of a periphery of an image stream

Apparatus and methods are described for imaging a portion of a body of a subject that undergoes a motion cycle, including acquiring a plurality of image frames of the portion of the subject's body. A given feature is identified in at least some of the image frames. At least some image frames are image tracked with respect to the feature, and the image frames that have been image tracked with respect to the given feature are displayed as a stream of image frames. Visibility of a periphery of the displayed stream of image frames is at least partially reduced. Other applications are also described.

METHODS AND SYSTEMS FOR RETROSPECTIVE INTERNAL GATING

The present invention, in one form, is a method for deriving respiratory gated PET image reconstruction from raw PET data. In reconstructing the respiratory gated images in accordance with the present invention, respiratory motion information derived from individual voxel signal fluctuations, is used in combination to create usable respiratory phase information. Employing this method allows the respiratory gated PET images to be reconstructed from PET data with out the use of external hardware, and in a fully automated manner. 1. A method for retrospective internal gating comprising:{'b': '1', 'acquiring a series of images at times t . . . tn including a moving object;'}extracting time-activity information for voxels of the images;generating a time varying object motion function based on the extracted time-activity information for the voxels of the images;determining, using the time varying object motion function, phase information for motion of the moving object; andgenerating an updated series of images correcting for the motion of the moving object using the determined phase information for motion of the moving object.21. The method of claim 1 , wherein time-activity information is defined as a voxel's value over times t . . . tn.31. The method of claim 1 , further comprising assigning weighting factors to voxels claim 1 , wherein the weighting factors include voxel specific weighting factors based on the mean voxel activity over times t . . . tn.4. The method of claim 1 , further comprising assigning weighting factors to voxels claim 1 , wherein the weighting factors include voxel specific weighting factors based upon the voxel's proximity to greater spatial signal gradients on an ungated image.51. The method of claim 4 , wherein the ungated image is comprised of combined image data from times t . . . tn.61. The method of claim 1 , further comprising assigning weighting factors to voxels claim 1 , wherein the weighting factors include voxel specific weighting ...

VITAL SIGNS INFORMATION SYNCHRONIZATION SYSTEM, VITAL SIGNS INFORMATION SYNCHRONIZATION METHOD, AND VITAL SIGNS INFORMATION DETECTING SENSOR

A first vital signs information detecting sensor and a second vital signs information sensor are attached to a living body. The first vital signs information detecting sensor detects over time first vital signs information and first motion information of the living body. The first vital signs information and the first motion information are transmitted from the first vital signs information detecting sensor to a receiver. The second vital signs information detecting sensor detects over time second vital signs information and second motion information of the living body. The second vital signs information and the second motion information are transmitted from the second vital signs information detecting sensor to the receiver. The first vital signs information and the second vital signs information are displayed on a display of the receiver in a synchronized state, on the basis of the first motion information and the second motion information. 1. A vital signs information synchronization system comprising:a first vital signs information detecting sensor;a second vital signs information detecting sensor; andan information processing device,wherein the first vital signs information detecting sensor and the second vital signs information detecting sensor are configured to be attached on a living body; a first vital signs information detecting section configured to detect over time first vital signs information of the living body;', 'a first motion detecting section configured to detect over time first motion information of the living body; and', 'a first transmitting section configured to transmit to the information processing device the first vital signs information detected by the first vital signs information detecting section and the first motion information detected by the first motion detecting section;, 'wherein the first vital signs information detecting sensor comprises a second vital signs information detecting section configured to detect over time second ...

PATCH-BASED PHYSIOLOGICAL SENSOR

The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest. 1. A sensor for measuring photoplethysmogram (PPG) and electrocardiogram (ECG) waveforms and blood oxygen (SpO2) values from a patient , the sensor comprising:a housing worn entirely on the patient's chest;a heating element attached to a bottom surface of the housing so that it contacts and heats an area of the patient's chest when the housing is worn on the patient's chest;a temperature sensor in direct contact with the heating element;an optical system comprised by the housing, the optical system comprising a light source configured to generate optical radiation in both the red spectral region and infrared spectral region, the optical sensor oriented within the housing so that the optical radiation irradiates the area of the patient's chest, and a photodetector configured to generate a red PPG waveform by detecting optical radiation in the red spectral region that reflects off the area after it is heated by the heating element, the photodetector further configured to generate an infrared PPG waveform by detecting optical radiation in the infrared spectral region that reflects off the area after it is heated by the heating element;an ECG sensor comprising two electrode leads and an ECG circuit, the ECG circuit configured to receive ...

Device and Method for Measuring and Displaying Bioelectrical Function of the Eyes and Brain

Apparatus, system, and computer-readable media measure electroencephalography (EEG) signals or ERG signals generated from a device that presents a series of images on a timing cycle to a subject. The apparatus comprises a Central Processing Unit (CPU), Power Supply Unit (PSU), Random Access Memory (RAM), and a hard drive (HDD). The apparatus further includes at least one electrode and a photo-sensor like a photodiode for conversion of light into electric current. The CPU is operable with software for converting the EEG or ERG signals evoked from the visual stimuli to provide data and retrieving the status of EEG signals.

NON-CARTESIAN RETROSPECTIVE RECONSTRUCTION OF CARDIAC MOTION IN PATIENTS WITH SEVERE ARRHYTHMIA

A retrospective reconstruction method uses cardiac self-gating for patients with severe arrhythmias. Self-gated myocardial systolic and diastolic motion is determined from low-spatial and high-temporal resolution images and then the MRI-data-set is retrospectively reconstructed to obtain high quality images. The method uses undersampled image reconstruction to obtain the low-spatial and high-temporal resolution images, including those of different beat morphologies. Processing of these images is utilized to generate a cardiac phase signal. This signal allows for arrhythmia detection and cardiac phase sorting. The cardiac phase signal allows for detection of end-systolic and diastolic events which allows for improved sampling efficiency. In the case of frequent and severe arrhythmia, the method utilizes data from the normal and interrupted beats to improve sampling and image quality. 1. A method of retrospectively reconstructing moving cardiac images with high resolution , comprising:obtaining cardiac magnetic resonance data from a subject which allows for reconstruction of low spatial resolution and high temporal resolution cardiac images;applying image processing to the obtained low spatial resolution cardiac images to create a cardiac phase signal;applying arrhythmia detection and cardiac phase sorting to the cardiac phase signal to estimate the types of heart beats and estimate the cardiac phase for each data sample; andapplying the cardiac phase information to perform a retrospectively gated reconstruction.2. The method according to claim 1 , further comprising obtaining cardiac data using a k-space sampling trajectory that allows for the reconstruction of low-spatial and high-temporal resolution images from a subset of the data.3. The method according to claim 1 , further comprising obtaining cardiac data using a golden angle radial k-space sampling trajectory by the magnetic resonance imaging device.4. The method according to claim 1 , further comprising ...

METHODS AND SYSTEMS FOR BREATH DELIVERY SYNCHRONIZATION

Systems and methods for triggering inspiration and/or cycling exhalation with a ventilator are described herein. In particular, systems and methods for synchronizing ventilator breath delivery with patient breath demand utilizing a digital sample counting trigger mode are described herein. The digital sample counting triggering mode characterizes digital samples taken from a measured or estimated parameter during the patient inhalation/exhalation period to synchronize breath delivery with patient breath demand. 120-. (canceled)21. A method for ventilating a patient with a ventilator , comprising:monitoring a physiological parameter of the patient based on one or more received sensor measurements;calculating a first derivative of the physiological parameter for a first sample period; comparing a first trigger count threshold to a previous trigger count threshold selected in a previous sample period,', 'comparing the first derivative to a previous first derivative calculated for the previous sample period, and', 'comparing the first derivative to a first level;, 'updating a sample count to form a first updated sample count for the first sample period based on first comparison results from at least one of the followingcomparing the first updated sample count to the first trigger count threshold; andtriggering inspiration based on a first result of the comparing of the first updated sample count to the first trigger count threshold.22. The method of claim 21 , wherein the first result is that the first updated sample count is equal to the first trigger count threshold.23. The method of claim 21 , wherein the comparing of the first updated sample count to the first trigger count threshold has a second result claim 21 , wherein the second result is that the first updated sample count is not equal to the first trigger count threshold.24. The method of claim 23 , further comprising:calculating a next first derivative of the physiological parameter for a second sample period ...

Medical imaging with ecg triggering

A method is for medical imaging of a patient using a medical imaging system with ECG triggering. In an embodiment, the method includes capturing a respiration signal of the patient including n respiration cycles; concurrently capturing an ECG signal of the patient including m heartbeat intervals; determining a respiration-dependent heartbeat model based upon the n respiration cycles and the m heartbeat intervals; specifying at least one trigger time-point based upon the respiration-dependent heartbeat model; and starting the medical imaging at the specified trigger time-point.

GATING WITH ANATOMICALLY VARYING DURATIONS

A method for reconstructing a radioactive emission image of an overall volume having first and second volumetric regions, each volumetric region having respectively independent dynamic characteristics. The method comprises the following steps: a) obtaining radioactive emissions from the overall volume, including the volumetric regions, b) reconstructing an initial radioactive emission image of the volumetric region according to the radioactive emissions, c) segmenting the initial radioactive emission image to delineate the first and second volumetric regions, and d) separately reconstructing the first and the second volumetric regions according to the respectively independent dynamic characteristics. 1. A method for reconstructing a radioactive emission image of an overall volume having first and second volumetric regions , each volumetric region having respectively independent dynamic characteristics , the method comprising:(a) obtaining a structural image of the overall volume, including said volumetric regions, by a structural imager, selected from the group consisting of a CT, an MRI, and an ultrasound, to delineate said first and second volumetric regions;b) delineating said first and second volumetric regions;c) obtaining radioactive emissions from the overall volume, including said volumetric regions;d) separately reconstructing said first and second volumetric regions according to said respectively independent dynamic characteristics.2. The method of wherein said separately reconstructing is an iterative process including using object implantation for refining reconstruction of at least one of the first and second volumetric regions.3. The method of claim 2 , wherein at least one of the volumetric regions comprises at least a part of a body organ or other body portion; and providing a model of only a part of said overall volume, said model comprising a general location and shape of, and expected number of photons emitted from, said body organ or said at ...

SYSTEM AND METHOD FOR PRODUCING TEMPORALLY RESOLVED IMAGES DEPICTING LATE-GADOLINIUM ENHANCEMENT WITH MAGNETIC RESONANCE IMAGING

Systems and methods for late gadolinium enhancement (“LGE”) tissue viability imaging in a dynamic (e.g., temporal-ly-resolved) manner using magnetic resonance imaging (“MRI”) are provided. Dynamic LGE images can be generated throughout the entire cardiac cycle at high temporal resolution in a single breath-hold. Dynamic, semi-quantitative longitudinal relaxation maps are acquired and retrospective synthetization of dynamic LGE images is implemented using those semi-quantitative longitudinal relaxation maps. 1. A method for using a magnetic resonance imaging (MRI) system to produce an image of a subject who has been administered a contrast , the steps of the method comprising:(a) establishing a selected magnetization state in a tissue of the subject using the MRI system;(b) after the selected magnetization state is established, applying a T1-preparation radio frequency (RF) pulse to generate inverted magnetization in the tissue of the subject;(c) while the inverted magnetization in the tissue of the subject is recovering and until the selected magnetization state is established again, acquiring a data set at each of a plurality of different cardiac phases by sampling k-space in a k-space segment;(d) repeating steps (b) and (c) for a selected number of inversion recovery periods such that a plurality of data sets are acquired for each of the plurality of different cardiac phases;(e) reconstructing images from the plurality of data sets;(f) producing maps of a longitudinal relaxation parameter by fitting the images to a signal model; and(g) synthesizing an image that depicts a late-gadolinium enhancement contrast from the maps of the longitudinal relaxation parameter.2. The method as recited in claim 1 , wherein the T1-preparation RF pulse is applied at a time based on a detection of a physiological trigger event measured from the subject.3. The method as recited in claim 2 , wherein the physiological trigger event is an occurrence of an R-wave in an electrocardiograph ...

Determining a characteristic of a lumen by measuring velocity of a contrast agent

Apparatus and methods are described for use with a plurality of angiographic image frames of a moving lumen of a subject, including aligning the image frames with each other. Using the aligned image frames, a time it takes a contrast agent to travel a known distance through the lumen is determined. At least partially in response thereto, a characteristic of the lumen is determined, and, in response to the determined characteristic, an output is generated on a display. Other applications are also described.

Highly reliable ingestible event markers and methods for using the same

Ingestible event markers having high reliability are provided. Aspects of the ingestible event markers include a support, a control circuit, a first electrochemical material, a second electrochemical material and a membrane. In addition, the ingestible event markers may include one or more components that impart high reliability to the ingestible event marker. Further, the ingestible event markers may include an active agent. In some aspects, the active agent, such as a pharmaceutically active agent or a diagnostic agent may be associated with the membrane.

MONITORING DEVICE INCLUDING COMPLIANT VARIABLE CAPACITOR FOR RESPIRATION AND CARDIAC SENSING APPLICATIONS

A monitoring device for obtaining data from a patient during a respiratory and/or cardiac cycle of the patient. The monitoring device includes a compliant variable capacitor securely attached to the patient The capacitance of the compliant variable capacitor changes during movement of the patient caused by the respiratory cycle and/or a cardiac cycle. The changing capacitance is used to generate a monitoring signal that includes the frequency, timing and amplitude of either the respiratory or cardiac cycle. The signal from the monitoring device is provided to a medical imaging system such that the medical imaging system can compensate for the motion of the patient during the reparatory/cardiac cycle. 1. A device for monitoring expansion and contraction of a thoracic or abdominal cavity of a patient , comprising:a movement sensor secured to the thoracic or abdominal cavity, wherein the movement sensor includes a compliant variable capacitor that changes capacitance as the thoracic or abdominal cavity expands and contracts; anda monitoring circuit that senses the changing capacitance and generates a monitoring signal that indicates the expansion and contraction of the thoracic or abdominal cavity.2. The device of wherein the movement sensor is formed as pan of a strap that surrounds the thoracic or abdominal cavity of the patient.3. The device of wherein the movement sensor is attachable to the patient by an adhesive.4. The device of wherein the compliant variable capacitor expands and contracts in omni-directions.5. The device of wherein the compliant variable capacitor includes a dielectric elastomer located between two electrodes.6. The device of wherein the movement sensor includes a plurality of compliant variable capacitors connected to each other in parallel.7. The device of further comprising a wireless transceiver coupled to the monitoring circuit to wirelessly transmit the monitoring signal from the device.8. The device of wherein the monitoring signal is ...

DATA PROCESSING APPARATUS, DATA PROCESSING METHOD, AND STORAGE MEDIUM STORING PROGRAM

A data processing apparatus includes: a data acquisition unit that acquires waveform data corresponding to biological information correlated with a heart rate and generates, on the basis of the acquired waveform data, a plurality of pieces of time series data whose starting timings are different from each other; a correlation value calculation unit that calculates an autocorrelation value of the plurality of pieces of time series data for each of a plurality of lags; and an image generation unit that generates the autocorrelation image data in which the autocorrelation values are indicated for each of coordinates corresponding to a plurality of combinations of a timing and a lag by mapping pixel values corresponding to autocorrelation values corresponding to the combinations of the timing and the lag to a coordinate plane, in which the timing is assigned to a first axis and the lag is assigned to a second axis. 1. A data processing apparatus comprising:a data acquisition unit that acquires waveform data corresponding to biological information correlated with a heart rate and generates, on the basis of the acquired waveform data, a plurality of pieces of time series data whose starting timings are different from each other;a correlation value calculation unit that calculates an autocorrelation value of the plurality of pieces of time series data for each of a plurality of lags;an image generation unit that generates the autocorrelation image data in which the autocorrelation values are indicated for each of coordinates corresponding to a plurality of combinations of a timing and a lag by mapping pixel values corresponding to autocorrelation values corresponding to the combinations of the timing and the lag to a coordinate plane, in which the timing is assigned to a first axis and the lag is assigned to a second axis; andan image output unit that outputs the autocorrelation image data.2. The data processing apparatus according to claim 1 , wherein the image generation ...

METHOD AND APPARATUS FOR IMPROVED FLOW LIMITATION DETECTION OF OBSTRUCTIVE SLEEP APNEA

In a respiratory apparatus for treatment of sleep apnea and other disorders associated with an obstruction of a patient's airway and which uses an airflow signal, an obstruction index is generated which detects the flattening of the inspiratory portion of the airflow. The flattening index serves as an obstruction index used to differentiate normal and obstructed breathing. The obstruction index is based upon comparison of values of airflow in different sectors of the inspiratory peak of the wave function and is particularly suitable for distinguishing M shaped or square shaped respiratory patters indicative of partially obstructed airways. 1. A method for the detection of inspiratory and expiratory half cycles in breathing comprisingdetecting the start of inspiration,provisionally taking the start of inspiration as the time that inspiratory airflow exceeds a predetermined threshold,rejecting the start of inspiration if the flow then falls below zero again before the total volume reaches a predetermined value,provisionally taking the start of expiration as the time that expiratory airflow falls below zero,rejecting the start of expiration if the airflow then goes above a predetermined value in the inspiratory direction before the total volume expired reaches a predetermined value.2. The method of further comprising trimming any end-expiratory pause that has been included in the inspiratory half cycle.3. The method of further comprising finding the earliest time at which inspiration could have started bylocating the time where flow first reaches a predetermined percentage of peak inspiratory flow,searching backwards to the time where the flow last reached a second predetermined percentage of the peak, andextrapolating backwards to find the time where flow should be zero.4. The method of further comprising reversing the approximate effect of a low pass filter on the flow-time curve by the steps of(a) passing the wave through an identical low pass filter a second time,( ...

Systems and Methods for Automated Medical Image Identification for Protocols

Method for identifying medical image records includes receiving a plurality of medical image records; receiving a protocol, the protocol including a plurality of measurements having an order; identifying a first medical image record of the plurality of medical image records, wherein a first measurement of the plurality of measurements can be performed on the first medical image record; displaying the first medical image record; receiving the first measurement; identifying a second medical image record of the plurality of medical image records, wherein a second measurement of the plurality of measurements can be performed on the second medical image record; displaying the second medical image record; and receiving the second measurement. 1) A method of identifying medical image records , comprising:receiving, at one or more computing devices, a plurality of medical image records;receiving, at the one or more computing devices, a protocol, the protocol including a plurality of measurements having an order;identifying, at the one or more computing devices, a first medical image record of the plurality of medical image records, wherein a first measurement of the plurality of measurements can be performed on the first medical image record;displaying, at the one or more computing devices, the first medical image record;receiving, at the one or more computing devices, the first measurement;identifying, at the one or more computing devices, a second medical image record of the plurality of medical image records, wherein a second measurement of the plurality of measurements can be performed on the second medical image record;displaying, at the one or more computing devices, the second medical image record; andreceiving, at the one or more computing devices, the second measurement.2) The method of claim 1 , wherein each medical image record of the plurality of medical image records comprises a Digital Imaging and Communications in Medicine (“DICOM”) Service-Object Pair ...

Retrospective retrofitting method to generate a continuous glucose concentration profile by exploiting continuous glucose monitoring sensor data and blood glucose measurements

Continuous Glucose Monitoring (CGM) devices provide glucose concentration measurements in the subcutaneous tissue with limited accuracy and precision. Therefore, CGM readings cannot be incorporated in a straightforward manner in outcome metrics of clinical trials e.g. aimed to assess new glycaemic-regulation therapies. To define those outcome metrics, frequent Blood Glucose (BG) reference measurements are still needed, with consequent relevant difficulties in outpatient settings. Here we propose a “retrofitting” algorithm that produces a quasi continuous time BG profile by simultaneously exploiting the high accuracy of available BG references (possibly very sparsely collected) and the high temporal resolution of CGM data (usually noisy and affected by significant bias). The inputs of the algorithm are: a CGM time series; some reference BG measurements; a model of blood to interstitial glucose kinetics; and a model of the deterioration in time of sensor accuracy, together with (if available) a priori information (e.g. probabilistic distribution) on the parameters of the model. The algorithm first checks for the presence of possible artifacts or outliers on both CGM datastream and BG references, and then rescales the CGM time series by exploiting a retrospective calibration approach based on a regularized deconvolution method subject to the constraint of returning a profile laying within the confidence interval of the reference BG measurements. As output, the retrofitting algorithm produces an improved “retrofitted” quasi-continuous glucose concentration signal that is better (in terms of both accuracy and precision) than the CGM trace originally measured by the sensor. In clinical trials, the so-obtained retrofitted traces can be used to calculate solid outcome measures, avoiding the need of increasing the data collection burden at the patient level.

DECEPTION DETECTION USING OCULOMOTOR, CARDIOVASCULAR, RESPIRATORY AND ELECTRODERMAL MEASURES

The present application discloses a deception detection systems and processes that use a processor; an eye tracking device connected to the processor, and a set of physiological sensors connected to the processor. The eye tracking device may comprise an infrared camera that is positioned to be able to track the oculomotor activity of a subject. The deception detection system also includes a respiratory sensor connected to the processor positioned to be able to track the respiration of the subject and an electrodermal sensor connected to the processor positioned to be able to detect the electrodermal activity of the subject. Additionally, the deception detection system includes a cardiovascular sensor connected to the processor positioned to be able to detect the cardiovascular activity of the subject and a speaker connected to the processor positioned to be able to transmit sound to the subject. 2. The system for deception detection assessment analysis of claim 1 , wherein the processor is presenting to the subject one or more questions to obtain an emotional assessment and extracting features from oculomotor data obtained by the eye-tracking device to calculate an emotional assessment from the assessment protocol.3. The system for deception detection assessment analysis of claim 2 , further comprising the processor calculating computing an overall probability of deception from the emotional assessment claim 2 , the cognitive load assessment claim 2 , and the first probability of deception.4. The system for deception detection assessment analysis of claim 1 , wherein the assessment protocol features questions directed to four issues of interest presented in a series of session claim 1 , with only questions directed to two of the four issues of interest presented in each session.5. The system for deception detection assessment analysis of claim 1 , further comprising a speaker connected to the processor positioned to be able to transmit sound to the subject; and the ...

METHODS AND SYSTEMS FOR RETROSPECTIVE INTERNAL GATING

The present invention, in one form, is a method for deriving respiratory gated PET image reconstruction from raw PET data. In reconstructing the respiratory gated images in accordance with the present invention, respiratory motion information derived from individual voxel signal fluctuations, is used in combination to create usable respiratory phase information. Employing this method allows the respiratory gated PET images to be reconstructed from PET data with out the use of external hardware, and in a fully automated manner. 1. A method for retrospective internal gating comprising:{'b': '1', 'acquiring a series of images at times t . . . tn including a moving object;'}extracting time-activity information for voxels of the images;determining phase information for motion of the moving object based on the time-activity information for voxels of the images; andgenerating an updated series of images correcting for the motion of the moving object using the determined phase information for motion of the moving object.2. The method of claim 1 , further comprising:generating a time varying object motion function based on the extracted time-activity information for the voxels of the images; andwherein determining the phase information further comprises determining the phase information using the time varying object motion function.31. The method of claim 1 , further comprising assigning weighting factors to voxels claim 1 , wherein the weighting factors include voxel specific weighting factors based on the mean voxel activity over times t . . . tn.4. The method of claim 1 , further comprising assigning weighting factors to voxels claim 1 , wherein the weighting factors include voxel specific weighting factors based upon the voxel's proximity to greater spatial signal gradients on an ungated image.51. The method of claim 4 , wherein the ungated image is comprised of combined image data from times t . . . tn.61. The method of claim 1 , further comprising assigning weighting ...

BIOIMPEDANCE BASED PULSE WAVEFORM SENSING

An arterial pulse wave may be determined via a system that includes a pressure transducing pad configured to temporarily attach to skin of a user and to deflect outwards from the skin proportionate to pressure applied by an artery. A sensor is configured to measure outward deflection of the pressure transducing pad. A plurality of electrodes are coupled to the pressure transducing pad and configured to interface with the skin of the user when the pressure transducing pad is attached to the skin of the user. The plurality of electrodes include electrodes configured to apply a current to the skin of the user, and electrodes configured to measure a voltage differential across the skin of the user. An arterial pulse wave may be determined based on at least the measured outward deflection and the measured voltage differential. 1. A system for determining an arterial pulse wave of a user , comprising:a pressure transducing pad temporarily attachable to skin of a user, the pressure transducing pad configured to deflect outwards from the skin proportionate to pressure applied by an artery;a sensor configured to measure outward deflection of the pressure transducing pad; anda plurality of electrodes coupled to the pressure transducing pad and configured to interface with the skin of the user when the pressure transducing pad is attached to the skin of the user, the plurality of electrodes comprising electrodes configured to apply a current to the skin of the user, and electrodes configured to measure a voltage differential across the skin of the user.2. The system of claim 1 , wherein the plurality of electrodes comprise two electrodes configured to apply a current to the skin of the user claim 1 , and further comprise two electrodes configured to measure a voltage differential across the skin of the user.3. The system of claim 2 , wherein the plurality of electrodes are thin strip electrodes arranged in parallel such that the two electrodes configured to apply a current to ...

AN APPARATUS CONFIGURATED TO AND A PROCESS TO PHOTOACOUSTICALL IMAGE AND MEASURE A STRUCTURE AT THE HUMAN EYE FUNDUS

An apparatus configured to photoacoustically image and measure a structure at the human eye fundus or components, substances, cells, tissue, or analytes within the eye and within the blood vessels of the eye including an emitter element for emitting electro-magnetic radiation, a transition element for delivering the electro-magnetic radiation into an eye, a detection element for detecting an acoustic wave and converting the acoustic wave into a digital wave signal, an analysis element for processing the digital wave signal into an image or measurement or both, and a display element for displaying a representation of the image and/or the measurement. The apparatus additionally includes a coupling member, the coupling member being configured and arranged to acoustically couple the eye to the detection element such that the acoustic wave generated within the eye can be guided onto the detection element. 1. An apparatus configured to photoacoustically image and measure a structure at the human eye fundus , comprising:an emitter element configured to emit electro-magnetic radiation;a transition element configured to deliver the electro-magnetic radiation into an eye;a detection element configured to detect an acoustic wave and convert the acoustic wave into a digital wave signal;an analysis element configured to process the digital wave signal into at least one of an image and a measurement;a display element configured to display a representation of at least one of the image and the measurement; anda coupling member configured and arranged to acoustically couple the eye to the detection element such that the acoustic wave generated within the eye is capable of being guided onto the detection element.2. The apparatus according to claim 1 , wherein the emitter element comprises one or more light sources configured to emit electro-magnetic radiation claim 1 , as beams of different wavelengths claim 1 , and a beam combiner configured to combine the beams of different ...

Control using an uncertainty metric

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for an exosuit activity transition control structure. In some implementations, sensor data representing an estimate of sensor data that will be produced by sensors of an exosuit at a particular time in the future is generated, where the exosuit is configured to assist mobility of a wearer. Actual sensor data that is generated using the sensors of the exosuit is obtained. A measure of uncertainty is determined based on the forecasted sensor data and the actual sensor data. Based on the measure of uncertainty, a control action for the exosuit to adjust an assistance provided to the wearer is determined.

Automatic quantitative vessel analysis

Apparatus and methods are described including designating within an image of blood vessels of a subject, a target portion of the blood vessels. In response to a first input from a user that designates a single point on the image, a first location within the blood vessels in a vicinity of the designated point is designated. In response to second and third inputs from the user, proximal and distal locations within the target portion are designated. The target portion is designated such that the target portion passes from the proximal location of the target portion to the distal location of the target portion, and such that the target portion includes the first location. Quantitative vessel analysis is performed on the target portion of the blood vessels, and an output is generated based upon the quantitative vessel analysis. Other applications are also described.

VOXEL TAGGING USING FIBER OPTIC SHAPE SENSING

A voxel tagging system (100) includes a sensing enabled device (104) having an optical fiber (126) configured to sense induced strain within the device (Bragg grating sensor). An interpretation module (112) is configured to receive signals from the optical fiber interacting with an internal organ, e.g. heart, and to interpret the signals to determine positions visited by the at least one optical fiber within the internal organ. A data source (152, 154) is configured to generate data associated with an event or status, e.g. respiration, ECG phase, time stamp, etc.. A storage device (116) is configured to store a history (136) of the positions visited in the internal organ and associate the positions with the data generated by the data source (152, 154). 1. A system , comprising:a sensing enabled device having at least one optical fiber configured to sense induced strain within the device;an interpretation module configured to receive signals from the at least one optical fiber interacting with a volume and to interpret the signals to determine positions visited by the at least one optical fiber within the volume;a data source configured to generate data associated with an event or status; anda storage device configured to store a history of the positions visited in the volume and associate the positions with the data generated by the data source.2. The system as recited in claim 1 , wherein the data source includes a clock and the storage device stores timestamps associated with the positions in the volume.3. The system as recited in claim 1 , wherein the shape sensing enabled device is included in a medical device and the volume includes an internal cavity in a body.4. The system as recited in claim 1 , wherein the data source includes a monitoring device that monitors one or more health parameters and the storage device stores health parameter data associated with the positions in the volume.5. The system as recited in claim 1 , wherein the data source includes at ...

METHOD AND SYSTEM FOR CREATING A ROADMAP FOR A MEDICAL WORKFLOW

A method for creating a roadmap for a medical workflow includes providing a multidimensional image-dataset including a plurality of images of a predefined organ combined with a number of state-dimensions characterizing a movement state of a moving organ. Measured pilot tone data is provided from a continuous pilot tone signal acquisition. A coordinate is determined for each state-dimension based on the measured pilot tone data, and an image of the multidimensional image-dataset is selected based on the number of determined coordinates of each state dimension. 1. A method for creating a roadmap for a medical workflow , the method comprising:providing a multidimensional image-dataset comprising a plurality of images of a predefined organ combined with a number of state-dimensions characterizing a movement state of a moving organ;providing measured pilot tone data from a continuous pilot tone signal acquisition;determining a coordinate for each state-dimension based on the measured pilot tone data; andselecting an image of the multidimensional image-dataset based on a number of determined coordinates of each state dimension.2. The method of claim 1 , further comprising performing an image acquisition parallel to the continuous pilot tone signal acquisition;wherein the measured pilot tone data is used to match an acquired image with a corresponding predefined image of the multidimensional image-dataset, andwherein the image acquisition is configured such that a device is trackable in a patient.3. The method of claim 2 , wherein:the measurement of the pilot tone data is connected with a measurement of a central k-space region of the image acquisition;in the course of determining the coordinate for each state-dimension, the pilot tone data measured at the central k-space region is used; ora combination thereof.4. The method of claim 1 , wherein intervals of the measured pilot tone data respective to a predefined time period are stored in the course of pilot tone signal ...

METHODS AND SYSTEMS FOR RETROSPECTIVE INTERNAL GATING

The present invention, in one form, is a method for deriving respiratory gated PET image reconstruction from raw PET data. In reconstructing the respiratory gated images in accordance with the present invention, respiratory motion information derived from individual voxel signal fluctuations, is used in combination to create usable respiratory phase information. Employing this method allows the respiratory gated PET images to be reconstructed from PET data with out the use of external hardware, and in a fully automated manner. 1. A method for retrospective internal gating comprising:{'b': '1', 'acquiring image data corresponding to times t . . . tn to be used to generate one or more images corresponding to a moving object;'}extracting information for a plurality of arrays derived from the image data;generating a time varying object motion function based on the extracted information for the plurality of arrays of the image data;determining, based on the time varying object motion function, phase information for motion of the moving object; andgenerating at least one image correcting for the motion of the moving object based on the determined phase information for motion of the moving object and the acquired image data.21. The method of claim 1 , wherein information is defined as a signal of an array element over times t . . . tn.31. The method of claim 1 , further comprising assigning weighting factors to the plurality of arrays claim 1 , wherein the weighting factors include array specific weighting factors based on the mean array activity over times t . . . tn.4. The method of claim 1 , further comprising assigning weighting factors to the plurality of arrays claim 1 , wherein the weighting factors include array specific weighting factors based upon the array's proximity to greater spatial signal gradients on a non-corrected image.51. The method of claim 4 , wherein the non-corrected image is comprised of combined image data from times t . . . tn.61. The method of ...

APPARATUS, MEDICAL INFORMATION PROCESSING APPARATUS, AND COMPUTER PROGRAM PRODUCT

A medical image diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to obtain a plurality of pieces of first medical information indicating wall motion parameters in a first local region and in a first global region, with respect to the heart of a first patient. The processing circuitry is configured to determine abnormality in the first local region on the basis of the plurality of pieces of first medical information. 1. An apparatus comprising processing circuitry configured to:obtain a plurality of pieces of first medical information indicating wall motion parameters in a first local region and in a first global region, with respect to a heart of a first patient; anddetermine abnormality in the first local region on a basis of the plurality of pieces of first medical information.2. The apparatus according to claim 1 , wherein the processing circuitry determines the abnormality in the first local region of the first patient claim 1 , by inputting the plurality of pieces of first medical information of the first patient to a trained model trained by using claim 1 , with respect to hearts of a plurality of second patients claim 1 , a plurality of pieces of second medical information indicating wall motion parameters in a second local region and in a second global region and abnormality determination results with respect to the second local region.3. The apparatus according to claim 2 , whereinthe wall motion parameters include pieces of information that are of mutually-different types with respect to at least one selected from among: temporal phases before and after either a load or medical treatment; positions in a wall thickness direction; and heart motion directions, andthe plurality of pieces of second medical information include information that is of same types as the plurality of pieces of first medical information.4. The apparatus according to claim 3 , whereineach of the first global region ...

AUTOMATED COMPUTATION OF TRIGGER DELAY FOR TRIGGERED MAGNETIC RESONANCE IMAGING SEQUENCES

A magnetic resonance (MR) imaging device () repeatedly executes a navigator pulse sequence () to generate navigator data in image space as a function of time, and a motion signal () of an anatomical feature that moves with a physiological cycle (e.g. respiration) as a function of time is extracted from the navigator data. A concurrent physiological signal () as a function of time is generated by a physiological monitor () concurrently with the repeated execution of the navigator pulse sequence. A gating time offset () is determined by comparing the motion signal of the anatomical feature as a function of time and the concurrent physiological signal as a function of time. The MR imaging device performs a prospective or retrospective gated MR imaging sequence () using gating times defined as occurrence times of gating events detected by the physiological monitor modified by the gating time offset. 1. A gating device for a magnetic resonance (MR) imaging device , the gating device comprising:a physiological monitor;an electronic processor; anda non-transitory storage medium storing a navigator pulse sequence, a gated MR imaging sequence, and instructions readable and executable by the electronic processor to perform a gated MR imaging method including:operating the MR imaging device to repeatedly execute the navigator pulse sequence to generate navigator data in image space as a function of time;extracting a motion signal of an anatomical feature as a function of time from the navigator data;concurrently with operating the MR imaging device to repeatedly execute the navigator sequence, acquiring a concurrent physiological signal as a function of time generated by the physiological monitor;determining a gating time offset by comparing the motion signal of the anatomical feature as a function of time and the concurrent physiological signal as a function of time by computing a time corresponding to a phase shift between the motion signal of the anatomical feature and the ...

MULTI-PARAMETER PHYSIOLOGICAL MAPPING

A map generator can be programmed to generate a multi-parameter graphical map by encoding at least two different physiological parameters for a geometric surface, corresponding to tissue of a patient, using different color components of a multi-dimensional color model such that each of the different physiological parameters is encoded by at least one of the different color components. 1. One or more non-transitory computer-readable media having data and machine readable instructions executable by a processor , the data comprising electroanatomical data corresponding to electrophysiological signals measured by a plurality of sensors from tissue of a patient , the machine readable instructions comprising a mapping system that comprises: compute a first set of physiological parameter data based on the electroanatomical data;', 'encode the first set of physiological parameter data to a first color component representing a dimension of a multi-dimensional color model;', 'compute a second set of physiological parameter data different from the first set of physiological parameter data based on the electroanatomical data; and', 'encode the second set of physiological parameter data to a second color component representing another dimension of the multi-dimensional color model; and, 'a physiological parameter calculator programmed toa map generator programmed to generate output data corresponding to a multi-parameter graphical map for a geometric surface corresponding to the tissue of the patient by mapping the first and second set physiological parameter data to respective color components of the multi-dimensional color model, wherein the mapping system is programmed to provide the output data to a therapy system for delivery of a therapy to the patient.2. The one or more media of claim 1 , wherein the mapping system is further programmed to configure one or more control parameters for the delivery of the therapy to the tissue of the patient based the output data.3. The one ...

Magnetic resonance imaging apparatus and magnetic resonance imaging method

A magnetic resonance imaging apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to set a rotation angle of a non-Cartesian trajectory in a k-space on the basis of information related to cyclic movements of a subject to be imaged, to obtain k-space data by rotating the non-Cartesian trajectory at the set rotation angle, and to generate an image by reconstructing the k-space data.

MAGNETIC RESONANCE IMAGING APPARATUS AND IMAGE PROCESSING APPARATUS

A magnetic resonance imaging apparatus according to an embodiment includes a sequence controller and a storage unit. The sequence controller acquires magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject. The storage unit stores therein the magnetic resonance signals acquired at the time phases. 1. An image processing apparatus comprising:an analyzing unit that extracts a cerebrospinal fluid (CSF) region from a magnetic resonance (MR) image; andan input unit that receives an input to specify a cerebral ventricle portion region on the MR image from which the CSF region is extracted,wherein the analyzing unit further extracts a cerebral sulcus portion region based on the specified cerebral ventricle portion region.2. The image processing apparatus according to claim 1 , wherein the input unit receives an input to specify a region of interest (ROI) that encompasses the cerebral ventricle portion region.3. The image processing apparatus according to claim 1 , wherein the analyzing unit generates a mask of the cerebral sulcus portion region by using the CSF region and the specified cerebral ventricle portion region.4. The image processing apparatus according to claim 3 , wherein the analyzing unit generates the mask of the cerebral sulcus portion region by subtracting a mask of the cerebral ventricle portion region from the CSF region.5. The image processing apparatus according to claim 4 , wherein the analyzing unit applies the mask of the cerebral sulcus portion region and the mask of the cerebral ventricle portion region to the MR image claim 4 , and extracts signal values of the cerebral sulcus portion region and the cerebral ventricle portion region.6. An image processing apparatus comprising:an analyzing unit that extracts a cerebrospinal fluid (CSF) region from a magnetic ...

Magnetic Resonance Imaging with Asymmetric Radial Sampling and Compressed-Sensing Reconstruction

A method for acquiring cine images using a magnetic resonance imaging (MRI) system includes selecting an asymmetric radial sampling scheme providing an asymmetric view of k-space corresponding to a desired image resolution. Radial k-space data is acquired using the asymmetric radial sampling scheme, wherein slice-orientation of the radial k-space data is continuously modified while acquiring the radial k-space data. A plurality of cine images are reconstructed from the radial k-space data using a compressed-sensing method. 1. A method for acquiring cine images using a magnetic resonance imaging (MRI) system , the method comprising:selecting an asymmetric radial sampling scheme providing an asymmetric view of k-space corresponding to a desired image resolution;acquiring radial k-space data using the asymmetric radial sampling scheme, wherein slice-orientation of the radial k-space data is continuously modified while acquiring the radial k-space data; andreconstructing a plurality of cine images from the radial k-space data using a compressed-sensing method.2. The method of claim 1 , wherein the asymmetric radial sampling scheme is an interleaved-angle asymmetric radial sampling scheme.3. The method of claim 2 , wherein the interleaved-angle asymmetric radial sampling scheme comprises:a full-echo sampling scheme portion to be applied in a center region of k-space; anda secondary sampling scheme portion to be applied in a remaining area of k-space which excludes the center region of k-space.4. The method of claim 2 , wherein the interleaved-angle asymmetric radial sampling scheme is a weak asymmetry sampling scheme.5. The method of claim 2 , wherein the interleaved-angle asymmetric radial sampling scheme is a strong asymmetry sampling scheme.6. The method of claim 2 , wherein the interleaved-angle asymmetric radial sampling scheme is a half-echo sampling scheme.7. The method of claim 2 , wherein the interleaved-angle asymmetric radial sampling scheme distributes the ...

Biological information detection system, wearable biological information detection device, and biological information detection method

A biological information detection system includes a wearable biological information detection device, a stationary biological information detection device, and a control unit. When data from the stationary biological information detection device is received by a first communication unit, the control unit calculates a correlation value between first biological information detected by a first detection unit and second biological information included in the data, and when the calculated correlation value satisfies a predetermined correlation condition, the control unit causes the wearable biological information detection device to start monitoring the second biological information included in the data, as biological information of a wearer.

GUIDEWIRE APPARATUS AND METHOD FOR MULTIPLE PARAMETER ANALYSIS OF CORONARY STENOSIS

A Percutaneous Coronary Intervention (PCI) guidewire and method of use includes at least two pairs of small surface area, closely spaced electrodes spaced axially along the length of the guidewire to allow one electrode pair to be positioned on each side of a coronary stenosis. The electrodes can sense electrical signals from the myocardium immediately adjacent to the electrodes, enabling the guidewire to record and analyze an Intra-Coronary Electrogram (ICEG) and heart pacing, and, therefore, facilitate more accurately diagnosis of an individual patient's stenosis and provide a more patient specific diagnosis of clinical need. 1. An intravascular device:an elongate tubular body having a distal end region, anda plurality of electrode pairs disposed on an exterior surface of the elongate tubular body proximate the distal end region and actually spaced thereapartwherein the plurality of electrode pairs are electrically couplable to one of a signal source and measurement circuit.2. The intravascular device of wherein the plurality of electrode pairs comprises a proximal pair of closely spaced electrodes and a distal pair of closely spaced electrodes wherein the ratio of the interelectrode distance between the proximal pair of electrodes in the distal pair of electrodes to the intra-electrode distance between electrodes within a pair is in the range between 5:1 to 40:1.3. The intravascular device of wherein the plurality of electrode pairs comprises a proximal pair of closely spaced electrodes and a distal pair of closely spaced electrodes wherein the ratio of the interelectrode distance between the proximal pair of electrodes in the distal pair of electrodes to the intra-electrode distance between electrodes within a pair is in the range between 7:1 to 25:1.4. The intravascular device of wherein the plurality of electrode pairs comprises a proximal pair of closely spaced electrodes and a distal pair of closely spaced electrodes wherein the ratio of the interelectrode ...

IMAGING APPARATUS, LOCAL COIL AND METHOD FOR CORRECTING A PATIENT MOVEMENT

The disclosure relates to an imaging apparatus for acquiring image data from a diagnostically-relevant body region of a patient comprising a sensor and a correction unit, wherein the at least one sensor is embodied to output a signal containing information on movement of the diagnostically relevant body region of the patient and the correction unit is embodied to receive the signal from the at least one sensor, and to apply a correction method in dependence on the signal to reduce the influence of the movement of the diagnostically relevant body region of the patient on an imaging examination. The disclosure further relates to a local coil for acquiring magnetic resonance signals in a frequency and power range of a magnetic resonance measurement, and a method for correcting patient movement. 1. An imaging apparatus for acquiring image data from a diagnostically-relevant body region of a patient , comprising:a sensor configured to output a signal containing information on a movement of the diagnostically-relevant body region of the patient, the sensor being a non-imaging sensor, and the signal being based upon the movement of the diagnostically-relevant body region of the patient; andcorrection circuitry configured to apply a correction technique based upon on the signal received from the sensor to reduce an influence of the movement of the diagnostically-relevant body region of the patient on an imaging examination.2. The imaging apparatus as claimed in claim 1 , wherein the imaging apparatus is a magnetic resonance imaging system claim 1 , and further comprising:a local coil positioned according to an application on the diagnostically-relevant body region of the patient, and configured to receive magnetic resonance signals in a frequency and power range corresponding to a magnetic resonance measurement,wherein the local coil includes the sensor, andwherein the sensor is configured as an acceleration sensor, a gyro sensor, and/or a Hall sensor.3. The imaging ...

System and method for automatically monitoring physiological parameters of a subject

A method and assembly for monitoring physiological parameters of a subject is provided. The method includes measuring, with a physiological sensor, data that indicates a change in a value of a physiological parameter of a subject over a time period. The method further includes measuring, with a motion sensor, data that indicates a value of a motion of the subject over the time period. The method further includes determining, with a processor, whether the value of the motion of the subject over the time period is less than a motion threshold. The method includes determining, with the processor, whether the change in the value of the physiological parameter over the time period exceeds a change threshold. The method also includes performing an action based on the determination that the change in the value of the physiological parameter exceeds the change threshold.

System for monitoring and presenting health, wellness and fitness data with feedback and coaching engine

A nutrition and activity management system is disclosed that monitors energy expenditure of an individual through the use of a body-mounted sensing apparatus. The apparatus is particularly adapted for continuous wear. The system is also adaptable or applicable to measuring a number of other physiological parameters and reporting the same and derivations of such parameters. A weight management embodiment is directed to achieving an optimum or preselected energy balance between calories consumed and energy expended by the user. An adaptable computerized nutritional tracking system is utilized to obtain data regarding food consumed, Relevant and predictive feedback is provided to the user regarding the mutual effect of the user's energy expenditure, food consumption and other measured or derived or manually input physiological contextual parameters upon progress toward said goal.

Smart Patient Monitoring

A patient monitoring method wherein data is received from a transducer by an electronic device, the electronic device receives input from the patient regarding timing of various events, the data is processed to incorporate the event timing data, and the data is then transmitted to a terminal. The terminal is accessible by, e.g., a healthcare provider. The transducer is used to perform medical diagnostic tests, such as fetal non-stress tests, electrocardiography, Holter monitoring, and electroencephalography. In the event that an emergency is identified, the healthcare provider can take immediate action. The utilization of an electronic device, e.g., a smartphone, by patients not only ensures ease of use and compliance with testing, but also conveniently allows patients to take an active role in their healthcare.

SYSTEM AND METHOD FOR AUTOMATICALLY MONITORING PHYSIOLOGICAL PARAMETERS OF A SUBJECT

A method and assembly for monitoring physiological parameters of a subject is provided. The method includes measuring, with a physiological sensor, data that indicates a change in a value of a physiological parameter of a subject over a time period. The method further includes measuring, with a motion sensor, data that indicates a value of a motion of the subject over the time period. The method further includes determining, with a processor, whether the value of the motion of the subject over the time period is less than a motion threshold. The method includes determining, with the processor, whether the change in the value of the physiological parameter over the time period exceeds a change threshold. The method also includes performing an action based on the determination that the change in the value of the physiological parameter exceeds the change threshold. 1. An assembly comprising:a first physiological sensor configured to measure data that indicates a change in a value of a first physiological parameter of a subject over a time period;a second physiological sensor configured to measure data that indicates a change in a value of a second physiological parameter of a subject over the time period;at least one processor; andat least one memory including one or more sequences of instructions, determine whether the change in the value of the first physiological parameter exceeds a first change threshold;', 'receive data from the second physiological sensor over the time period if the change in the value of the first physiological parameter exceeds the first change threshold;', 'determine whether the change in the value of the second physiological parameter exceeds a second change threshold; and', 'perform an action based on the determination that the change in the value of the second physiological parameter exceeds the second change threshold., 'the at least one memory and the one or more sequences of instructions configured to, with the at least one processor, ...

SYSTEMS AND METHODS FOR MATCHING AND IMAGING TISSUE CHARACTERISTICS

Systems and methods for matching a characteristic of multiple sectors of a moving tissue to verify an overlap thereof are disclosed herein. In an exemplary method, tissue data for at least a first sector and a second sector of a moving tissue is acquired. A characteristic of at least a portion of the first and second sectors is estimated from the acquired tissue data, and the estimated characteristics are matched to verify whether a portion of the first sector overlaps with a portion of the second sector. Estimating can include estimating a displacement such as an axial displacement and/or lateral displacements. Estimating can further include estimating a strain, a velocity, a strain rate and/or a stiffness or equivalent. 1. A method for matching a characteristic of two or more sectors of a moving tissue to verify whether any portions thereof overlap , comprising:acquiring tissue data for at least a first sector and a second sector of said moving tissue;estimating a characteristic of at least a portion of said first sector and a characteristic of at least a portion of said second sector from said acquired tissue data; andmatching said estimated characteristic of said portion of said first sector with said estimated characteristic of said portion of said second sector, to verify whether said portion of said first sector overlaps with said portion of said second sector.2. The method of claim 1 , further comprising determining a time delay between said matched characteristic of said portion of said first sector and said matched characteristic of said portion of said second sector.3. The method of claim 2 , further comprising forming an image of said matched characteristic of said portion of said first sector and said matched characteristic of said portion of said second sector utilizing said determined time delay.4. The method of claim 1 , wherein estimating said characteristic further comprises estimating a displacement.5. The method of claim 1 , wherein estimating ...

Implantable medical system for measuring a physiological parameter

An implantable medical system includes at least four electrodes forming a dipole emitter and a dipole receiver which is distinct from the dipole emitter. The system is configured to recover physiological mechanical information by way of the two dipoles, by analyzing a received and processed electrical signal, wherein the amplitude has been modulated in accordance with the electrical properties of the propagation medium between the dipole emitter and the dipole receiver. Thus, a parameter which is representative of a pre-ejection period may be extracted from the attenuation of the voltage between the dipole emitter and the dipole receiver by taking an electrocardiogram or an electrogram into account.

SYSTEM AND METHOD FOR ONSET/OFFSET CAPTURE

A medical device is utilized to monitor physiological parameters of a patient and capture segments of the monitored physiological parameters. The medical device includes circuitry configured to monitor one or more physiological parameters associated with the patient and an analysis module that includes a buffer and a processor. The buffer stores monitored physiological parameters and the processor analyzes the monitored physiological parameters and triggers capture of segments from the buffer in response to a triggering criteria being satisfied. The analysis module selects a pre-trigger duration based at least in part on the triggering criteria. 1. A system comprising: a housing configured for subcutaneous implantation within a patient, the housing having a length from a proximal end of the housing to a distal end of the housing, a width, and a depth, wherein the length is greater than the width and the width is greater than the depth;', 'a proximal electrode in proximity to the proximal end of the housing;', 'a distal electrode in proximity to the distal end of the housing;', 'sensing circuitry within the housing, the sensing circuitry configured to sense an electrocardiogram (ECG) of the patient via the proximal electrode and the distal electrode;', 'wireless communication circuitry within the housing;', 'a memory within the housing; and', determine whether a triggering criterion is satisfied based on the ECG;', 'store a segment of the ECG in the memory based on satisfaction of the triggering criterion, wherein the segment of the ECG includes a pre-trigger duration prior to satisfaction of the triggering criterion; and', 'control the wireless communication circuitry to transmit the segment of the ECG,, 'a processor within the housing, the processor configured to], 'an insertable cardiac monitor (ICM) comprising receive the segment of ECG data; and', 'transmit an updated setting to the ICM based on the segment of ECG data., 'a remote monitoring center configured ...

METHODS AND SYSTEMS FOR RETROSPECTIVE INTERNAL GATING

The present invention, in one form, is a method for deriving respiratory gated PET image reconstruction from raw PET data. In reconstructing the respiratory gated images in accordance with the present invention, respiratory motion information derived from individual voxel signal fluctuations, is used in combination to create usable respiratory phase information. Employing this method allows the respiratory gated PET images to be reconstructed from PET data without the use of external hardware, and in a fully automated manner. 1. A method for retrospective internal gating , the method comprising:{'sub': 1', 'n, 'acquiring image data corresponding to successive digital images ito ito obtain a chronologically ordered image set with temporally cyclical signals corresponding to periodic motion of a moving object;'}{'sub': 1', 'n, 'extracting information for a plurality of arrays corresponding to one or more voxels in the successive images ito i;'}generating a time varying object motion function based on the extracted information for the plurality of arrays of the image data;determining, based on the time varying object motion function, phase information for the periodic motion of the moving object; andgenerating at least one image correcting for the periodic motion of the moving object based on the acquired image data and the determined phase information for the periodic motion of the moving object.2. The method of claim 1 , wherein information is defined as a signal of an array element over times t. . . tcorresponding to images ito i.3. The method of claim 1 , further comprising assigning weighting factors to the plurality of arrays claim 1 , wherein the weighting factors include array specific weighting factors based on the mean array activity over times t. . . tcorresponding to images ito i.4. The method of claim 1 , further comprising assigning weighting factors to the plurality of arrays claim 1 , wherein the weighting factors include array specific weighting ...

Ultrafast tracer imaging for positron emission tomography

The disclosed embodiments relate to a system that performs ultra-fast tracer imaging on a subject using positron emission tomography. During operation, the system performs a high-temporal-resolution, total-body dynamic PET scan on the subject as an intravenously injected radioactive tracer propagates through the vascular system of the subject to produce PET projection data. Next, the system applies an image reconstruction technique to the PET projection data to produce subsecond temporal frames, which illustrate the dynamic propagation of the radioactive tracer through the vascular system of the subject. Finally, the system outputs the temporal frames through a display device.

Image diagnostic apparatus and method, and recording medium

The image diagnostic method includes acquiring an electrocardiogram (ECG) signal of an object, selecting a scan protocol used to reconfigure a heart image of the object, based on the acquired ECG signal, and providing a user with information used to propose the selected scan protocol.

TECHNIQUES FOR ANALYZING NON-VERBAL MARKERS OF CONDITIONS USING ELECTROPHYSIOLOGICAL DATA

Embodiments related to analyzing brain activity of a subject to identify signs associated with binocular rivalry. Sensed electrical activity of a subject's brain is received over a time period while the subject is exposed to a visual stimulus. The sensed electrical activity comprises a first frequency band associated with a first frequency of a first image presented to the subject's left eye, a second frequency band associated with a second frequency of a second image presented to the subject's right eye. A set of events in the time period is determined based on the frequency bands, wherein an event is associated with a change from a previous perceptual event to a new perceptual event. A metric for the subject is determined based on the set of events. The metric is analyzed to determine whether the subject exhibits signs associated with a condition that is associated with binocular rivalry. 1. A computerized method for analyzing brain activity of a subject associated with the subject's vision to identify signs associated with binocular rivalry , the method comprising: ["a first frequency band associated with a first frequency of a first image presented to the subject's left eye; and", "a second frequency band associated with a second frequency of a second image presented to the subject's right eye;"], "receiving sensed electrical activity of a subject's brain over a time period while the subject is exposed to a visual stimulus, wherein the sensed electrical activity comprises:"}determining, based on the first and second frequency bands, a set of events in the time period, wherein an event in the set of events is associated with a change from a previous perceptual event triggered by observation of the first and second images by the subject to a new perceptual event triggered by observation of the first and second images by the subject;determining, based on the set of events, a metric for the subject; andanalyzing the metric to determine whether the subject exhibits ...

Diagnostically useful results in real time

A method for real-time vascular modeling and assessment is disclosed. Modeling, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels and construct 3-D vascular extents and determine other vascular characteristics. Assessment, in some embodiments, comprises processing models selectively different from one another to produce one or more vascular indexes which indicate a diagnostic preference, for example, to perform a medical intervention such as a stent implantation. Speed is achieved, for example, by the method being optimized for determining the effects of a medical intervention. In some embodiments, results are produced quickly enough to allow use of the method to perform PCI within the same catheterization used to perform diagnostic imaging.

SYSTEMS AND METHODS FOR CARDIOVASCULAR-DYNAMICS CORRELATED IMAGING

A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient. 1. A method for cardiovascular-dynamics correlated imaging , comprising:receiving a time series of images of at least a portion of a patient;receiving a time series of cardiovascular data for the patient;evaluating correlation between temporal variation in the time series of images and temporal variation in the time series of cardiovascular data;identifying vascularized tissue of the patient based upon the correlation; anddetermining a property of the patient, relating to the vascularized tissue, based upon the correlation.2. (canceled)3. The method of claim 1 , the step of receiving a time series of images comprising receiving a time series of electrical impedance tomography images.45-. (canceled)6. The method of claim 1 , further comprising generating the time series of images as a time series of electrical impedance tomography images.711-. (canceled)12. The method of claim 1 , the step of receiving a time series of cardiovascular data comprising receiving a time series of pulse-oximetry data.1316-. (canceled)17. The method of claim 1 , the step of evaluating correlation comprising analyzing ...

Synthetically Trained Neural Network for MRI Tag Tracking

A method for magnetic resonance imaging (MRI) tag tracking includes: synthetically generating tagged data from natural images combined with programmed tag motion and a full Bloch simulation; training a convolutional neural network (CNN) with the synthetically generated tagged data to generate grid tag motion paths; acquiring MRI images using a tagged imaging method; inputting the acquired images into the CNN to estimate motion paths of tracked points; and determining from the estimated motion paths a path of tag lines through the cardiac cycle from a set of tagged MRI images. The method can calculate strain curves from the estimated motion paths using Ederivation. 1. A method for magnetic resonance imaging (MRI) tag tracking , the method comprising:synthetically generating tagged data from natural images combined with programmed tag motion and a full Bloch simulation;training a convolutional neural network (CNN) with the synthetically generated tagged data to generate grid tag motion paths;acquiring MRI images using a tagged imaging method;inputting the acquired images into the CNN to estimate motion paths of tracked points;determining from the estimated motion paths a path of tag lines through the cardiac cycle from a set of tagged MRI images.2. The method of wherein the convolutional neural network (CNN) includes both coordinate convolutions and (2+1)D convolutions.3. The method of further comprising calculating strain curves from the estimated motion paths using strain tensor derivation.4. The method of wherein the tagged imaging method comprises applying tagging pulses asynchronously with an ECG trigger claim 1 , and including a time-from-tagging sampling dimension in tagged data.. This application claims priority from US Provisional Patent Application 62/963123 filed Jan. 19, 2020, and from US Provisional Patent Application 62/963124 filed Jan. 19, 2020, both of which are incorporated herein by reference.The present invention relates generally to medical ...

MONITORING PHYSIOLOGOGY

A physiological monitoring system comprising a sensor device for attachment to the skin of a subject, the sensor device comprising at least a first sensor for sensing a physiological parameter of the subject and a processing device configured for analysing data sensed by the sensor by means of a predetermined algorithm to estimate whether the data is indicative of a disease condition, and on detecting such a condition to generate an alert. It is further described a method for monitoring a plurality of subjects comprising the step of providing each subject with a sensor device as referred to above and then analysing data sensed by the sensors such as to preferentially generate an alert if the data received from multiple ones of the sensors demonstrate a contemporaneous trend indicative of a disease condition. 2. (canceled)3. A physiological monitoring system as claimed in claim 1 , wherein each sensor device further comprises an accelerometer.4. A physiological monitoring system as claimed in claim 2 , wherein the system is configured to selectively analyse data gathered by the first and second temperature sensors at times dependent on data gathered by the accelerometer.5. A physiological monitoring system as claimed in claim 3 , wherein the system is configured to claim 3 , in dependence on data sensed by the accelerometer during a sleep session of each subject claim 3 , form an estimate of the quality of the subject's sleep during that session and to estimate whether the data is indicative of a disease condition in dependence on that sleep quality estimate.6. (canceled)7. A physiological monitoring system as claimed in claim 3 , wherein the system is configured to selectively analyse temperature data gathered at times of relatively low acceleration as sensed by the accelerometer.8. A physiological monitoring system as claimed in claim 5 , wherein the system is configured to form an estimate of the lowest temperature attained by a wearer of the device during a sleep ...

Methods, Apparatuses and Systems Useful in Conducting Image Guided Intervensions

Methods, apparatuses, and systems relating to image guided interventions on dynamic tissue. One embodiment is a method that includes creating a dataset that includes images, one of the images depicting a non-tissue internal reference marker, being linked to non-tissue internal reference marker positional information, and being at least 2-dimensional. Another embodiment is a method that includes receiving a position of an instrument reference marker coupled to an instrument; transforming the position into image space using a position of a non-tissue internal reference marker implanted in a patient; and superimposing a representation of the instrument on an image in which the non-tissue internal reference marker appears. Computer readable media that include machine readable instructions for carrying out the steps of the disclosed methods. Apparatuses, such as integrated circuits, configured to carry out the steps of the disclosed methods. Systems that include devices configured to carry out steps of the disclosed methods. 140-. (canceled)41. A method comprising:receiving, from an imaging device, an image signal that includes a plurality of images, each image depicting a non-tissue internal reference marker;calculating a transformation from tracking space to image space for each image based on a position of the non-tissue internal reference marker and linking the transformation for each image to the corresponding image, and calculating a dataset vector using a position of the non-tissue internal reference marker and a position of an external reference marker;receiving, from a tracker, a current position of the non-tissue internal reference marker;selecting one of the plurality of images based on the current position of the non-tissue internal reference marker;linking the dataset vector with the one of the plurality of images;receiving, from the tracker, a current position of an instrument reference marker coupled to an instrument;applying the transformation linked to ...

METHODS AND SYSTEMS FOR PROCESSING MOLECULAR IMAGING DATA BASED ON ANALYSIS OF A RESPIRATORY MOTION WAVEFORM

Methods and systems are provided for analyzing a respiratory motion waveform acquired during acquiring imaging data with a molecular imaging device. In one embodiment, a method comprises acquiring imaging data with a molecular imaging apparatus, analyzing a respiratory motion waveform acquired during the acquiring imaging data, and applying gating to the acquired imaging data based on the analyzed respiratory motion waveform. In this way, gating may be applied to the acquired imaging data in order to generate an image for medical diagnosis with increased image quality and accuracy. 1. A method , comprising:acquiring imaging data with a molecular imaging apparatus;analyzing a respiratory motion waveform acquired during the acquiring imaging data; andapplying gating to the acquired imaging data based on the analyzed respiratory motion waveform.2. The method of claim 1 , further comprising generating an image from the gated acquired imaging data and displaying the image to a user.3. The method of claim 1 , wherein the respiratory motion waveform is a one-dimensional waveform generated from the acquired imaging data.4. The method of claim 1 , wherein the respiratory motion waveform is a one-dimensional waveform acquired from a sensor coupled to a patient being scanned with the molecular imaging apparatus.5. The method of claim 1 , wherein analyzing the respiratory motion waveform includes: finding a peak amplitude of a cycle and dividing the cycle into a first segment before the peak amplitude and a second segment after the peak amplitude, where each cycle is defined between adjacent valleys of the respiratory motion waveform;', 'determining a first slope of the first segment and a second slope of the second segment; and', 'determining whether a difference between the first slope and the second slope is greater than a threshold., 'for each cycle of the respiratory motion waveform6. The method of claim 5 , further comprising claim 5 , for each cycle claim 5 , marking the ...

System and methods for generating predictive combinations of hospital monitor alarms

Systems and methods are disclosed for monitoring data associated with a plurality of physiological characteristics of a patient, comprising: the methods include generating a set of super-alarm patterns associated with the plurality of physiological conditions, wherein the super-alarm patterns comprising data relating to a combination of at least two individual raw alarms from independent physiological data streams that co-occur within a temporal window, and triggering an alarm if a combination of the input physiological data matches at least a portion of a generated super-alarm pattern.

APPARATUS AND METHOD FOR ESTIMATING BLOOD PRESSURE

An apparatus for estimating blood pressure includes: a ballistocardiogram (BCG) sensor configured to measure a limb BCG signal from a user; and a processor configured to obtain blood pressure-related features from the measured limb BCG signal, according to sensing characteristics of the BCG sensor, and estimate a blood pressure of the user based on the obtained blood pressure-related features. 1. An apparatus for estimating blood pressure , the apparatus comprising:a ballistocardiogram (BCG) sensor configured to measure a limb BCG signal from a user; and obtain blood pressure-related features from the measured limb BCG signal, according to sensing characteristics of the BCG sensor, and', 'estimate a blood pressure of the user based on the obtained blood pressure-related features., 'a processor configured to2. The apparatus of claim 1 , wherein the sensing characteristics of the BCG sensor comprise at least one of a type and a measurement position of the BCG sensor.3. The apparatus of claim 1 , wherein the processor comprises a model calibrator configured to calibrate a reference limb BCG prediction model based on the limb BCG signal measured from the user claim 1 , so as to generate a personalized limb BCG prediction model according to the sensing characteristics of the BCG sensor.4. The apparatus of claim 3 , wherein the model calibrator is further configured to:select at least one parameter from among a plurality of parameters of the reference limb BCG prediction model, andgenerate the personalized limb BCG prediction model by adjusting the selected at least parameter based on the measured limb BCG signal.5. The apparatus of claim 4 , wherein the model calibrator is further configured to claim 4 , based on the sensing characteristics of the BCG sensor indicating that the BCG sensor is an acceleration sensor worn on a wrist of the user claim 4 , select at least one of mass claim 4 , elasticity claim 4 , and attenuation as the at least one parameter.6. The apparatus ...

METHODS OF IDENTIFYING AND LOCATING TISSUE ABNORMALITIES IN A BIOLOGICAL TISSUE

A method of identifying and locating tissue abnormalities in a biological tissue includes irradiating an electromagnetic signal, via a probe defining a transmitting probe, in the vicinity of a biological tissue. The irradiated electromagnetic signal is received at a probe, defining a receiving probe, after the signal is scattered/reflected by the biological tissue. Blood flow information pertaining to the biological tissue is provided. Based on the received irradiated electromagnetic signal and the blood flow information, tissue properties of the biological tissue are reconstructed. A tracking unit determines the position of at least one of the transmitting probe and the receiving probe while the step of receiving is being carried out, the at least one probe defining a tracked probe. The reconstructed tissue properties are correlated with the determined probe position so that tissue abnormalities can be identified and spatially located. 1. A method of identifying and locating tissue abnormalities in a biological tissue , comprising:irradiating an electromagnetic signal, via a transmitting probe, in the vicinity of a biological tissue, the electromagnetic signal being a first electromagnetic signal;at a receiving probe, receiving the irradiated electromagnetic signal after the signal is scattered/reflected by the biological tissue, and the received electromagnetic signal being a second electromagnetic signal;processing the first and second electromagnetic signals in conjunction with a signal representing a blood circulation cycle of the biological tissue;providing blood flow information pertaining to the biological tissue based at least partly on the basis of the processing step;communicating at least some of the provided blood flow information to a tissue properties reconstruction process;via the tissue properties reconstruction process, reconstructing tissue properties of the biological tissue based in part on the second electromagnetic signal;determining, via a ...

SYSTEMS AND METHODS FOR DETECTING PATIENT STATE IN A MEDICAL IMAGING SESSION

Methods and systems are provided for detecting patient motion during a diagnostic scan. In one example, a method for a medical imaging system includes obtaining output from one or more patient monitoring devices configured to monitor a patient before and during a diagnostic scan executed with the medical imaging system, receiving a request to initiate the diagnostic scan, tracking patient motion based on the output from the one or more patient monitoring devices, and initiating the diagnostic scan responsive to patient motion being below a threshold level. 1. A method for a medical imaging system , comprising:obtaining output from one or more patient monitoring devices configured to monitor a patient before and/or during a diagnostic scan executed with the medical imaging system;receiving a request to initiate the diagnostic scan;tracking patient motion based on the output from the one or more patient monitoring devices; andinitiating the diagnostic scan responsive to patient motion meeting a predetermined condition.2. The method of claim 1 , further comprising claim 1 , upon initiating the diagnostic scan claim 1 , tracking patient motion based on the output from the one or more patient monitoring devices claim 1 , and if patient motion exceeds a threshold level claim 1 , taking an action based on the patient motion.3. The method of claim 2 , wherein taking an action based on the patient motion comprises pausing the diagnostic scan until patient motion reaches or drops below the threshold level.4. The method of claim 2 , wherein taking an action based on the patient motion comprises tagging data acquired by the medical imaging system while the patient motion exceeds the threshold level.5. The method of claim 4 , further comprising claim 4 , when patient motion reaches or drops below the threshold level claim 4 , reacquiring the data that was acquired by the medical imaging system while the patient motion exceeded the threshold level.6. The method of claim 2 , ...

Assessment of Hemodynamic Function In Arrhythmia Patients

Electrocardiogram (ECG)-gated cardiac magnetic resonance imaging (MRI) alone may be unable to capture the hemodynamics associated with arrhythmic events. As a result, values such as ejection fraction are acquisition dependent. The desired RR-duration determines the arrhythmia rejection. By combining real-time volume measurements with ECG recordings, beat morphologies can be categorized and a more comprehensive evaluation of ventricular function during arrhythmia can be provided. 1. A method for evaluating hemodynamic function of the heart by:obtaining continuous cardiac imaging data;obtaining physiologic data synchronous to the cardiac imaging data;analyzing the physiologic data to determine multiple observed cardiac contraction morphologies; andestimating hemodynamic information for each of the cardiac contraction morphologies using the cardiac imaging data.2. The method of claim 1 , wherein estimating the hemodynamic information includes estimating global hemodynamic information for each beat morphology by combining regional hemodynamic estimates.3. The method of claim 2 , wherein the cardiac imaging data is used to obtain the regional hemodynamic information.4. The method of claim 3 , further comprising producing a comprehensive hemodynamic quantification report based on observed beat morphologies and global hemodynamic information.5. The method of claim 1 , wherein the cardiac imaging data is heart chamber imaging data.6. The method of claim 5 , wherein the heart chamber imaging data is magnetic resonance imaging (MRI) data.7. The method of claim 1 , wherein the continuous cardiac imaging data is a two-dimensional 2D multi-slice MRI acquisition.8. The method of claim 1 , wherein the cardiac imaging data is a 2D golden angle radial acquisition.9. The method of claim 1 , wherein the physiologic data is a heart signal.10. The method of claim 1 , wherein the physiologic data is electrocardiogram (ECG) data.11. The method of wherein the cardiac imaging data is 2D ...

SYSTEMS AND METHODS FOR CARDIOVASCULAR-DYNAMICS CORRELATED IMAGING

A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient. 1. A method for evaluating tissue for cancer , comprising:receiving a time series of images of one or more regions of a patient;receiving a time series of cardiovascular data for the patient, the time series of cardiovascular data being recorded concurrently with the time series of images;evaluating a correlation between temporal variation in the time series of images and temporal variation in the time series of cardiovascular data, the correlation including at least one of temporal correlation and spectral correlation;identifying, in the images, vascularized tissue of the patient based upon the correlation; andevaluating the vascularized tissue of the patient for cancer based upon the images and based upon the correlation.2. The method of claim 1 , the step of receiving a time series of images comprising: generating the time series of images as a time series of electrical impedance tomography images and receiving the time series of electrical impedance tomography images.3. The method of wherein the step of evaluating the correlation between temporal variation in the time series of images and ...

MAGNETIC RESONANCE IMAGING APPARATUS

A magnetic resonance imaging apparatus includes a controller and a deriving unit. The controller performs first imaging for acquiring first image data on a region including a target and the diaphragm, second imaging for acquiring, with application of motion detection pulses for detecting a respiratory phase, second image data including the target at a first respiratory phase and third image data including the target at a second respiratory phase different from the first respiratory phase, and third imaging for acquiring fourth image data. The deriving unit detects the position of the diaphragm from the first image data and derives a region to which the motion detection pulses are applied. In the performing of the second imaging, the controller detects a respiratory phase by the application of the detection pulses and controls timings at which the second image data and the third image data are acquired. 1. A magnetic resonance imaging apparatus comprising:a controller that performs first imaging for acquiring first image data, that performs second imaging for acquiring second image data and third image data, and that performs third imaging for acquiring fourth image data, the first image data being of a region including a target and a diaphragm, the second imaging and the third imaging being performed with application of motion detection pulses for detecting a respiratory phase, the second image data being of a region including the target at a first respiratory phase, the third image data being of a region including the target at a second respiratory phase being different from the first respiratory phase image; anda deriving unit that detects a position of the diaphragm from the first image data and that, on a basis of the detected position, derives a region to which the motion detection pulses are applied;wherein, in the performing of the second imaging, the controller detects the respiratory phase by the application of the motion detection pulses and, on a basis of ...

Magnetic Resonance Method And Apparatus For Quantitative Time-Resolved Assessment Of Tissue Displacement And Related Biomarker Parameters With Blood Suppression In The Whole Cardiac Cycle

Embodiments relate to acquiring magnetic resonance (MR) images with suppressed residual blood signal in the early cardiac phases, leading to images with a preferred dark-blood appearance throughout the entire cardiac cycle, which improves accuracy of subsequent post-processing algorithms. The acquisition of the desired blood suppressed tissue images is achieved through a double inversion recovery pulse in DENSE sequences. The double inversion recovery pulse is applied after an electrocardiogram (ECG) trigger at a beginning point of a repetition time period, followed by a displacement encoding module at an inversion time during the repetition time period and a readout module comprised of a plurality of frames during a remainder of the repetition time period. The displacement encoding module applies a labelling process on the tissue, while the readout module applies an un-labelling process. The readout module comprises an imaging sequence adapted to acquire DENSE images.

Systems And Methods For Noninvasive Spectral-Spatiotemporal Imaging of Cardiac Electrical Activity

A system and method for non-invasively generating a report of cardiac electrical activities of a subject includes determining, using cardiac electrical activation information, equivalent current densities (ECDs). The ECDs are assembled into time-course ECD information and a spectrum of the time-course ECD information is analyzed to determine peaks for spectral characteristics of atrial fibrillation (AF). The spectral characteristics of AF are correlated with potential electrical sources of the AF and a report is generated indicating the potential electrical sources of the AF spatially registered with the medical imaging data.

METHOD AND EKG TRIGGER DEVICE FOR CORRECTING AN EKG SIGNAL IN MAGNETIC RESONANCE IMAGE ACQUISITION

In a method to correct an EKG signal, the EKG signal is acquired, and used for R-spike triggering, during a magnetic resonance (MR) image acquisition sequence that produces interference signals in the EKG signal generated by gradient jumps, wherein the gradient jumps repeat at a fixed time interval, and wherein the duration of a cardiac cycle measured via the EKG signal is at least five times the time interval. During at least a first cardiac cycle, immediately after detection of the R-spike in the EKG signal no detection of the R-spike for triggering takes place for a dead time that is shorter than the duration of the cardiac cycle and during which the MR sequence is already running, and the EKG signal is acquired in that dead time as a reference signal. The reference signal is analyzed to extract interference signals that respectively repeat after the time interval, which are used to determine a correction signal having a duration equal to the time interval. During the further execution of the MR sequence, the correction signal, which is synchronously repeated in the time interval, at least outside of the dead time, is used to correct the measured EKG signal. 1. A method to correct an EKG signal , comprising:operating a magnetic resonance (MR) data acquisition unit in a data acquisition sequence that comprises gradient jumps that repeatedly, respectively occur at respective fixed time intervals from each other;while operating said MR data acquisition unit in said sequence, acquiring an EKG signal from a patient in the MR data acquisition unit, said EKG signal comprising a plurality of cardiac cycles each having an R-spike therein that is to be detected and used to trigger acquisition of MR data in said sequence, each of said cardiac cycles having a cycle duration that is at least five times said time interval, said EKG signal also comprising interference signals that results from said gradient jumps;providing said EKG signal to a processor and, in said processor, ...

RETROSPECTIVE RETROFITTING METHOD TO GENERATE A CONTINUOUS GLUCOSE CONCENTRATION PROFILE BY EXPLOITING CONTINUOUS GLUCOSE MONITORING SENSOR DATA AND BLOOD GLUCOSE MEASUREMENTS

Continuous Glucose Monitoring (CGM) devices provide glucose concentration measurements in the subcutaneous tissue with limited accuracy and precision. Therefore, CGM readings cannot be incorporated in a straightforward manner in outcome metrics of clinical trials e.g. aimed to assess new glycaemic-regulation therapies. To define those outcome metrics, frequent Blood Glucose (BG) reference measurements are still needed, with consequent relevant difficulties in outpatient settings. Here we propose a “retrofitting” algorithm that produces a quasi continuous time BG profile by simultaneously exploiting the high accuracy of available BG references (possibly very sparsely collected) and the high temporal resolution of CGM data (usually noisy and affected by significant bias). The inputs of the algorithm are: a CGM time series; some reference BG measurements; a model of blood to interstitial glucose kinetics; and a model of the deterioration in time of sensor accuracy, together with (if available) a priori information (e.g. probabilistic distribution) on the parameters of the model. The algorithm first checks for the presence of possible artifacts or outliers on both CGM datastream and BG references, and then rescales the CGM time series by exploiting a retrospective calibration approach based on a regularized deconvolution method subject to the constraint of returning a profile laying within the confidence interval of the reference BG measurements. As output, the retrofitting algorithm produces an improved “retrofitted” quasi-continuous glucose concentration signal that is better (in terms of both accuracy and precision) than the CGM trace originally measured by the sensor. In clinical trials, the so-obtained retrofitted traces can be used to calculate solid outcome measures, avoiding the need of increasing the data collection burden at the patient level. 1. A glucose monitoring system for monitoring a glucose level in a user , comprising:(a) a continuous glucose ...

METHODS OF IDENTIFYING AND LOCATING TISSUE ABNORMALITIES IN A BIOLOGICAL TISSUE

A method of identifying and locating tissue abnormalities in a biological tissue includes irradiating an electromagnetic signal, via a probe defining a transmitting probe, in the vicinity of a biological tissue. The irradiated electromagnetic signal is received at a probe, defining a receiving probe, after the signal is scattered/reflected by the biological tissue. Blood flow information pertaining to the biological tissue is provided. Based on the received irradiated electromagnetic signal and the blood flow information, tissue properties of the biological tissue are reconstructed. A tracking unit determines the position of at least one of the transmitting probe and the receiving probe while the step of receiving is being carried out, the at least one probe defining a tracked probe. The reconstructed tissue properties are correlated with the determined probe position so that tissue abnormalities can be identified and spatially located. 1. A method of identifying and locating tissue abnormalities in a biological tissue , comprising:irradiating an electromagnetic signal, via a probe, in the vicinity of a biological tissue, the probe defining a transmitting probe;at a probe, receiving the irradiated electromagnetic signal after the signal is scattered/reflected by the biological tissue, the probe defining a receiving probe;providing blood flow information pertaining to the biological tissue;based on the received irradiated electromagnetic signal and the blood flow information, reconstructing tissue properties of the biological tissue;determining, via a tracking unit, the position of at least one of the transmitting probe and the receiving probe while the step of receiving is being carried out, the at least one probe defining a tracked probe; andcorrelating the reconstructed tissue properties with the determined probe position so that tissue abnormalities can be identified and spatially located.2. The method of claim 1 , wherein the step of determining includes ...

SYSTEM AND METHOD FOR ONSET/OFFSET CAPTURE

A medical device is utilized to monitor physiological parameters of a patient and capture segments of the monitored physiological parameters. The medical device includes circuitry configured to monitor one or more physiological parameters associated with the patient and an analysis module that includes a buffer and a processor. The buffer stores monitored physiological parameters and the processor analyzes the monitored physiological parameters and triggers capture of segments from the buffer in response to a triggering criteria being satisfied. The analysis module selects a pre-trigger duration based at least in part on the triggering criteria. 1. A method of monitoring and capturing arrhythmic electrocardiogram (ECG) segments , the method comprising:monitoring one or more physiological parameters of a patient;triggering capture of a first segment in response to an onset trigger criteria being satisfied;triggering capture of a second segment in response to an abnormal condition trigger criteria being satisfied; anddiscarding the first segment if capture of the first segment is not followed by the abnormal condition trigger criteria being satisfied, wherein the onset trigger criteria is more sensitive than the abnormal condition trigger criteria.2. The method of claim 1 , wherein the captured first segment includes onset of the abnormal condition if the abnormal condition trigger criteria is satisfied.3. The method of claim 1 , wherein the first segment is defined by an onset pre-trigger duration.4. The method of claim 1 , wherein the onset trigger criteria is more sensitive than the abnormal condition trigger criteria.5. The method of claim 1 , wherein the captured first segment and the captured second segment are separated by a time gap.6. The method of claim 1 , further including incrementing an onset counter in response the onset triggering criteria being satisfied.7. The method of claim 1 , wherein one or more of the monitored physiological parameters is an ...

Determination of Physiological Cardiac Parameters as a Function of the Heart Rate

A method for determining physiological cardiac parameters as a function of a heart rate is provided. For at least two heart rates adjusted by a cardiac stimulation during the recording, in each case, a four-dimensional image data set of the heart showing the entire cardiac cycle is recorded using an X-ray device. The physiological cardiac parameters are determined by evaluation of the four-dimensional image data sets.

Ultrasonic diagnostic apparatus, image processing apparatus, and image processing method

An ultrasonic diagnostic apparatus according to an embodiment includes an ultrasonic probe and processing circuitry. The ultrasonic probe collects reflected wave data in a time series manner from a region of a subject in motion. The processing circuitry generates time-series volume data from the reflected wave data collected by the ultrasonic probe. The processing circuitry calculates at least either of volume information and motion information on a region of interest of the subject by performing processing including tracking using the volume data. The processing circuitry sets one or more feature positions that represent anatomical features in the region of interest. The processing circuitry displays an MPR image that passes through at least one of the feature positions. The processing circuitry outputs at least either of the volume information and the motion information that includes the feature positions as boundaries.

System for the capture and combined display of video and analog signals coming from electromedical instruments and equipment

A system is proposed for the acquisition and the combined displaying of video output signals, for example in the VGA standard, coming from a set of various instruments and apparatuses (), each of which reproduces at least a signal representing the evolution of a physiological parameter, a diagnostic image of a part of the body of a person, or both. The system collects a video signal in the section connecting each of the instruments and apparatuses () with a monitor (). The video signals are carried to a central unit () for collection and processing of the signals and then presented in a single image on a central monitor (). 1. A system for the capture and display of output signals coming from a set of various electromedical instruments and apparatuses , each comprising display means , for displaying the operations carried out by said electromedical instruments and apparatuses , and operations including a trend of at least one physiological parameter of a patient , or a diagnostic image or video clip taken during a diagnostic check-up or an operation , said system including:video signal shunt devices, installed in corresponding sections connecting the output signals of each of said instruments and apparatuses with corresponding related display means, said video shunt devices being fit to shunt said video signals in order to make the corresponding video outputs available in a corresponding standard as used by said instruments or apparatuses;a plurality of connections, respectively arranged between each video signal shunt device, and a central unit for collection and processing of signals;video capture mans provided in said central unit, connected to said plurality of connections, for capturing video outputs coming from said video signal shunt devices for making said video outputs available for storing in said central unit for combined display;synchronization means for synchronizing various images or sequences of images coming from said video capture means, and ...

PROCESS AND SIGNAL PROCESSING UNIT FOR DETERMINING A CARDIOGENIC SIGNAL

A process and unit for determining an estimate for a respiratory signal. Measured values are received, and a sum signal is generated, which is a superimposition of the respiratory signal to a cardiogenic signal. The unit detects heartbeats, and a respective heartbeat time period for each. An intermediate signal is calculated by compensating the influence of the cardiac activity on the sum signal. The unit determines an attenuation signal, which is an indicator of the average time curve of the contribution of the cardiogenic signal to the intermediate signal in a predefined reference heartbeat time period. An intermediate signal section is generated as a section of the intermediate signal in a heartbeat time period and intermediate signal sections are mapped to the reference heartbeat time period. The estimated respiratory signal is calculated with the use of the mapped intermediate signal sections and of the attenuation signal. 1. A process for determining an estimate for a respiratory signal , wherein the respiratory signal is correlated with an intrinsic breathing activity and/or with a mechanical ventilation of a patient , the process comprising the steps of:predefining a reference heartbeat time period; receiving measured values of at least one sum signal sensor, the at least one sum signal sensor being configured to measure a signal generated in the body of the patient;', 'generating a sum signal with the use of the measured values, the sum signal being configured to be a superimposition of the respiratory signal to be estimated and of a cardiogenic signal, configured to be correlated with cardiac activity of the patient;', 'detecting a plurality of heartbeats with use of the sum signal;', 'detecting a respective heartbeat time period, in which the heartbeat takes place, for each detected heartbeat with the use of the sum signal;', 'one of calculating an intermediate signal from the sum signal, the intermediate signal being configured to compensate an influence ...

VASCULAR FLOW ASSESSMENT

A vascular assessment apparatus is disclosed. The apparatus is configured to receive a stenotic model having measurements of a coronary vessel tree of a subject, the stenotic model created from a set of medical images recorded before the subject underwent a stent procedure. The apparatus is also configured to receive a post-medical image of the coronary vessel tree of the subject after the stent has been placed into the coronary vessel tree and identify vascular features within the post medical image that correspond to vascular features that are provided among the set of medical images. The apparatus is further configured to modify geometrical information for the corresponding vascular features in the stenotic model to create an updated stenotic model from the identified vascular features of the post medical image and calculate an index indicative of vascular function, based, at least in part, on the updated stenotic model. 1. (canceled)2. A vascular assessment apparatus comprising:a processor communicatively coupled to a medical imaging device; and receive a set of medical images of a coronary vessel tree of a subject from the medical imaging device, wherein a first of the medical images of the set was acquired from a first viewing angle, and a second of the images of the set was acquired from a second viewing angle;', 'perform image analysis to identify vascular features within and corresponding among the set of medical images;', 'combine geometrical information for the corresponding vascular features to produce a stenotic model of the coronary vessel tree, the stenotic model having measurements of the coronary vessel tree at locations along vessels of the coronary vessel tree;', 'determine a flow characteristic from the stenotic model;', 'calculate a first index indicative of vascular function, based, at least in part, on the flow characteristic from the stenotic model;', 'receive another medical image of the coronary vessel tree of the subject;', 'analyze the ...

Systems And Methods For Noninvasive Spectral-Spatiotemporal Imaging of Cardiac Electrical Activity

A system and method for non-invasively generating a report of cardiac electrical activities of a subject includes determining, using cardiac electrical activation information, equivalent current densities (ECDs). The ECDs are assembled into time-course ECD information and a spectrum of the time-course ECD information is analyzed to determine peaks for spectral characteristics of atrial fibrillation (AF). The spectral characteristics of AF are correlated with potential electrical sources of the AF and a report is generated indicating the potential electrical sources of the AF spatially registered with the medical imaging data. 120.-. (canceled)21. A system for non-invasively generating a report of cardiac electrical activities of a subject , the system comprising:a first input configured to receive anatomical information acquired from a region of interest in the subject including a heart of the subject;a second input configured to receive physiological information acquired from the subject related to the heart of the subject;a non-transitory memory having stored thereon instructions; determine, using the physiological information, equivalent current densities (ECDs);', 'determine, using the ECDs, dominant frequency (DF) information for the heart of the subject; and', 'generate a map of the heart of the subject using the anatomical information and the DF information illustrating a spatial distribution of electrical information over at least a portion of the heart of the subject., 'a processor configured to access the memory to receive and execute the instructions and, following the instructions, to22. The system of wherein the processor is configured to assemble the ECDs into time-course ECD information and analyze a spectrum of the ECD information to determine peaks to generate the DF information.23. The system of wherein the processor is further configured to record body surface potential maps (BSPMs) from the subject and generate a heart-torso boundary element ...

System for monitoring and presenting health, wellness and fitness trend data with activity detection and feedback and coaching engine

A nutrition and activity management system is disclosed that monitors energy expenditure of an individual through the use of a body-mounted sensing apparatus. The apparatus is particularly adapted for continuous wear. The system is also adaptable or applicable to measuring a number of other physiological parameters and reporting the same and derivations of such parameters. A weight management embodiment is directed to achieving an optimum or preselected energy balance between calories consumed and energy expended by the user. An adaptable computerized nutritional tracking system is utilized to obtain data regarding food consumed, Relevant and predictive feedback is provided to the user regarding the mutual effect of the user's energy expenditure, food consumption and other measured or derived or manually input physiological contextual parameters upon progress toward said goal.

Method and system for radiation application

A method for generating one or more images includes collecting data samples representative of a motion of an object, acquiring image data of at least a part of the object over a time interval, synchronizing the data samples and the image data to a common time base, and generating one or more images based on the synchronized image data. A method for generating one or more images includes acquiring image data of at least a part of an object over a time interval, associating the image data with one or more phases of a motion cycle, and constructing one or more images using the image data that are associated with the respective one or more phases.

REGIONAL SATURATION SYSTEM WITH ENSEMBLE AVERAGING

A method may include receiving, at a processor, a first electromagnetic radiation signal and a second electromagnetic radiation signal from a regional oximetry sensor having two or more detectors and two or more emitters. The method may also include receiving, at the processor, a trigger signal that has a frequency corresponding to a periodic physical activity of a patient. Additionally, the method may include generating, via the processor, one or more ensemble averaged signals based at least in part on the first and second electromagnetic radiation signals and the trigger signal. Further, the method may include calculating, via the processor, a regional oxygen saturation value based at least in part on the one or more ensemble averaged signals and displaying, via a display, the regional oxygen saturation value. 1. A system , comprising:a regional oximetry sensor configured to generate a first electromagnetic radiation signal and a second electromagnetic radiation signal; and receive the first and second electromagnetic radiation signals from the regional oximetry sensor;', 'receive a trigger signal that has a frequency corresponding to a periodic physical activity of a patient;', 'generate one or more ensemble averaged signals based at least in part on the first and second electromagnetic radiation signals and the trigger signal;', 'determine the regional oximetry sensor is not disposed on the patient based at least in part on one or more features of the one or more ensemble averaged signals; and', 'generate a user-perceivable indication in response to a determination that the regional oximetry sensor is not disposed on the patient., 'a patient monitor comprising a processor configured to2. The system of claim 1 , wherein the one or more features comprise a pulse amplitude claim 1 , a pulse shape claim 1 , a pulse period claim 1 , a dicrotic notch claim 1 , or any combination thereof.3. The system of claim 1 , wherein the processor is configured to determine the ...

ROBOTIC SYSTEMS FOR NAVIGATION OF LUMINAL NETWORKS THAT COMPENSATE FOR PHYSIOLOGICAL NOISE

Certain aspects relate to systems and techniques for luminal network navigation. Some aspects relate to incorporating respiratory frequency and/or magnitude into a navigation system to implement patient safety measures. Some aspects relate to identifying, and compensating for, motion caused by patient respiration in order to provide a more accurate identification of the position of an instrument within a luminal network. 1. A system configured to navigate a luminal network of a patient , the system comprising:a field generator configured to generate an electromagnetic (EM) field;a set of one or more EM sensors at a distal end of a steerable instrument;a set of one or more respiration sensors;at least one computer-readable memory having stored thereon executable instructions; and access a preoperative model representative of the luminal network;', 'access a mapping between a coordinate frame of the EM field and a coordinate frame of the preoperative model;', 'calculate at least one position of the set of EM sensors within the EM field based on a data signal from the set of EM sensors;', 'calculate a frequency of respiration of the patient based on a data signal from the set of respiration sensors; and', 'determine a position of the distal end of the steerable instrument relative to the preoperative model based on the registration mapping, the frequency of the respiration, and the at least one position of the set of EM sensors within the EM field., 'one or more processors in communication with the at least one computer-readable memory and configured to execute the instructions to cause the system to at least2. The system of claim 1 , wherein the one or more processors are configured to execute the instructions to cause the system to at least:transform one or more data signals from the set of respiration sensors into a frequency domain representation of the one or more data signals; andidentify the frequency of respiration from the frequency domain representation of ...

MEDICAL ATTACHMENT DEVICE TRACKING SYSTEM AND METHOD OF USE THEREOF

A tracking system for tracking a medical attachment device within a tracking area, the tracking system including a first reflector defining a first tracking region, a medical attachment device having at least one reflector sensor operable to integrate the first reflector, and a processor communicatively coupled to the medical attachment device, the processor operable to determine a distance between the medical attachment device and the first reflector to determine a location of the medical attachment device relative to a subject. 116-. (canceled)17. A medical attachment device synchronization system comprising:a processor including a sound database storing a plurality of biological sounds;a medical attachment device communicatively coupled to the processor, the medical attachment device including a speaker; and detect a plurality of signals emitted by a subject;', 'synchronize the plurality of signals emitted by the subject to at least one of the plurality of biological sounds stored within the sound database; and', 'communicate the at least one of the plurality of biological sounds to the speaker., 'at least one sensor communicatively coupled the processor and operably configured to18. The medical attachment device synchronization system according to claim 17 , wherein:the at least one sensor is an orientation sensor coupled to the medical attachment device; andthe plurality of signals emitted by the subject correspond to a breathing cycle of the subject.19. The medical attachment device synchronization system according to claim 17 , wherein:the at least one sensor is an orientation sensor coupled to the medical attachment device; andthe plurality of signals emitted by the subject include at least one occurrence of a chest expansion and a chest contraction.20. The medical attachment device synchronization system according to claim 17 , wherein:the at least one sensor is an X-Y-Z axis accelerometer coupled to the medical attachment device.21. The medical attachment ...

Collecting and processing reliable ecg signals and gating puleses in a magnetic resonance environment

An electrocardiogram (ECG) electrode patch ( 10 ) system ( 50 ) for use in a magnetic resonance (MR) environment includes a flexible patch material ( 12 ) configured for attachment to human skin, and a plurality of electrodes ( 20 ). The electrodes ( 20 ) Care attached to the patch material ( 12 ) and configured to sense a plurality of ECG signals with different amplitudes across pairs of electrodes in at least two different directions.

DETERMINING PULSE WAVE TRANSIT TIME FROM PPG AND ECG/EKG SIGNALS

What is disclosed is a system and method for determining a pulse transit time for a subject. In one embodiment, the system comprises a handheld wireless cellular device configured with a sensor to acquire an electrocardiogram (ECG) signal from the subject and a photodetector generating a time-series signal in response to continuously sensing a reflection of source light off a region of exposed skin of the subject where a photoplethysmographic (PPG) signal can be detected by the photodetector. In one embodiment, the time-series signal is a PPG signal. In another embodiment, the time-series signal is processed to extract a PPG signal. A temporally overlapping segment of the PPG and ECG signals is analyzed to obtain a pulse transit time between a reference point on the PPG signal and a reference point on the ECG signal. The pulse transit time is used to assess pathologic conditions such as peripheral vascular disease. 1. A method for determining pulse wave transit time for a subject , comprising:receiving a time-series signal generated by a photodetector sensing an intensity of light reflected off a region of exposed skin of a subject where a photoplethysmographic (PPG) signal can be detected, said time-series signal comprising said PPG signal;receiving an electrocardiogram (ECG) signal obtained by a sensor placed on said subject's body where electrical activity of said subject's heart can be sensed; andprocessing a temporally overlapping segment of said PPG and ECG signals to determine a pulse transit time between a reference point on said PPG signal and a reference point on said ECG signal.2. The method of claim 1 , wherein claim 1 , in advance of processing said temporally overlapping segment of said PPG and ECG signals claim 1 , further comprising compensating for motion in said PPG signal induced by a movement of said subject.3. The method of claim 1 , wherein claim 1 , in advance of processing said temporally overlapping segment of said PPG and ECG signals claim ...

SYSTEMS AND METHODS FOR ADAPTIVE REPLANNING BASED ON MULTI-MODALITY IMAGING

Systems and methods directed to adaptive radiotherapy planning are provided. In some aspects, provided system and method include producing synthetic images from magnetic resonance data using relaxometry maps. The method includes applying corrections to the data and generating relaxometry maps therefrom. In other aspects, a method for adapting a radiotherapy plan is provided. The method includes determining an objective function based on dose gradients from an initial dose distribution, and generating an optimized plan based on updated images, using aperture morphing and gradient maintenance algorithms without need for organ-at-risk contouring. In yet other aspects, a method for obtaining 4D MR imaging using a temporal reshuffling of data acquired during normal breathing, a method for deformable image registration using a sequentially applied semi-physical model regularization method for multimodality images, and a method to generate 4D plans using an aperture morphing algorithm based on 4D CT or 4D MR imaging are provided. 1. A method for adapting a radiotherapy treatment plan , the method comprising:providing an initial radiotherapy plan to be adapted according to an updated image set, the initial radiotherapy plan having a radiation dose distribution;determining a plurality of dose gradients using the radiation dose distribution;defining an optimization objective using the dose gradients;receiving the updated image set;generating, using the updated image set, an updated set of contours representative of an updated target volume;forming a set of partial rings using the updated set of contours, the set of partial rings arranged about the updated set of contours representative of the updated target volume;performing a plan optimization using the optimization objective and the set of partial rings; andgenerating a report representative of an adapted radiotherapy plan obtained using the plan optimization.2. The method of claim 1 , wherein the plurality of dose ...

Prolapse detection and tool dislodgement detection

A tool dislodgement detection apparatus includes an MPS outputting position and orientation (P&O) readings for determining tool motion. A control generates an alarm based on the tool motion and dislodgement criteria. The criteria includes whether the tool motion meets a condition based on the type of medical procedure or tool, the tool parking position, a patient characteristic (e.g., age, weight, gender) or a physician preference. The criteria includes when the correlation between the tool motion and the cardiac, respiration and patient motion changes abruptly. In a prolapse detection apparatus, guidewire tip P&O readings determine a tip motion vector. The control generates an alarm using the motion vector and predetermined criteria. The criteria include a substantial change in the tip orientation not accompanied by a corresponding position change and a change in the motion vector by about 180° accompanied by a corresponding position change no greater than a threshold.

SURGICAL SYSTEM FOR DETECTING GRADUAL CHANGES IN PERFUSION

The present disclosure is directed to an augmented reality surgical system. The system includes an endoscope that captures an image of the region of interest of a patient and an ECG device that records an ECG of the patient. A controller receives the image and applies at least one image processing filter to the image. The image processing filter includes a decomposition filter that decomposes the image into frequency bands. A temporal filter is applied to the frequency bands to generate temporally filtered bands. An adder adds each band frequency band to a corresponding temporally filtered band to generate augmented bands. A reconstruction filter generates an augmented image by collapsing the augmented bands. The controller also receives the ECG and processes the augmented image with the ECG to generate an ECG filtered augmented image. A display displays the ECG filtered augmented image to a user. 1. An augmented reality surgical system comprising:an endoscope configured to capture an image of a region of interest of a patient;an electrocardiogram (ECG) device configured to record electrical activity of a heart of the patient; a decomposition filter configured to decompose the image into a plurality of frequency bands;', 'a temporal filter that is configured to be applied to the plurality of frequency bands to generate a plurality of temporally filtered bands;', 'an adder configured to add each band in the plurality of frequency bands to a corresponding band in the plurality of temporally filtered bands to generate a plurality of augmented bands;', 'a reconstruction filter configured to generate an augmented image by collapsing the plurality of augmented bands; and', 'an ECG filter configured to generate the ECG filtered augmented image based on the augmented image and the electrical activity; and, 'a controller configured to receive the image and apply at least one image processing filter to the image to generate an ECG filtered augmented image, the image ...

BLOOD PRESSURE MEASURING APPARATUS, SYSTEM, METHOD, AND PROGRAM

A measuring apparatus includes a biological sensor that detects biological information, a movement sensor that detects movement information of a living body as a target of the biological information, a determination unit that determines whether the body starts to move and whether the body is moving, based on the biological information and the movement information, a recording unit that records the biological information until a common value is obtained, if it is determined that the body starts to move, an analyzer that determines whether a history of a biological value of the biological information from when the biological value starts to decrease until the biological value reaches the common value is within a proper range, and a deleting unit that deletes a corresponding biological information from the recording unit if the history is within the proper range. 1. A blood pressure measuring apparatus comprising:a biological sensor configured to continuously detect biological information in time;a movement sensor configured to normally detect movement information of a living body as a target of the biological information;a determination unit configured to determine whether or not the living body starts to move and whether or not the living body is moving, by referring to the biological information and the movement information;a recording unit configured to record the biological information until a normal value is obtained, in a case where it is determined that the living body starts to move;an analyzer configured to determine whether or not a time history of a value of the biological information from when the value of the biological information starts to decrease until the value of the biological information reaches the normal value is within a proper range; anda deleting unit configured to delete a corresponding biological information from the recording unit in a case where the time history is within the proper range.2. The blood pressure measuring apparatus ...

Ultrasound image generation system for generating an intravascular ultrasound image

The invention relates to the field of intravascular ultrasound (IVUS) imaging IVUS images of a vessel (6) are provided, which have been determined based on IVUS signals acquired at different acquisition locations (9, 10) along the length of the vessel and at different acquisition times. Moreover, pressure values are provided, which are indicative of the pressure within the vessel at the acquisition times, wherein a combined IVUS image is generated by combining provided IVUS images that have been determined based on IVUS signals acquired at acquisition times at which the pressure values differ by less than a predefined deviation threshold from a reference pressure value. This use of the pressure within the vessel as a selection criterion for combining IVUS images can ensure that only IVUS images are combined, which correspond to a same vessel wall motion state, thereby reducing artifacts in the combined IVUS image.

A METHOD AND DEVICE FOR MAGNETIC RESONANCE IMAGING DATA ACQUISITION GUIDED BY PHYSIOLOGIC FEEDBACK

An adaptive real-time radial k-space sampling trajectory (ARKS) can respond to a physiologic feedback signal to reduce motion effects and ensure sampling uniformity. In this adaptive k-space sampling strategy, the most recent signals from an ECG waveform can be continuously matched to the previous signal history, new radial k-space locations c were determined, and these MR signals combined using multi-shot or single-shot radial acquisition schemes. The disclosed methods allow for improved 1. A method of making a Magnetic Resonance Imaging (MRI) image of a body part from MRI data , comprising:obtaining physiologic data;analyzing the physiologic data to determine at least one previous time that the body part was in a similar position to the current position;analyzing MRI hardware-controllable settings used at the at least one previous time to determine new MRI hardware-controllable settings;scanning the body part with the new MRI hardware-controllable settings to produce new MRI data; andproducing the MRI image using the new MRI data.2. The method of wherein the physiologic data is a heart signal.3. The method of claim 1 , wherein the physiologic data is an electrocardiogram (ECG).4. The method of claim 1 , wherein an autocorrelation on the physiologic data is done to determine the at least one previous time.5. The method of claim 1 , wherein the MRI hardware-controllable settings are settings to control the magnetic fields and radiofrequency pulses of the MRI and correspond to k-space values of the time domain MRI signal.6. The method of claim 5 , wherein the new MRI hardware-controllable settings are such that the k-space values for the new MRI hardware-controllable settings differ from the k-space values for MRI hardware-controllable settings.7. The method of claim 1 , wherein the new MRI data along with previous MRI data from the at least one previous time is used to produce the MRI image.8. The method of claim 1 , wherein the MRI image is a frame in an MRI cine.9 ...