20-03-2014 дата публикации
Номер: US20140076763A1
A peelable pouch comprises a substantially flat enclosure formed by first and second opposing flexible plies. A seat extends along at least a portion of a perimeter of the opposing plies. A flat, flexible transdermal patch is disposed in the enclosure and includes a bioactive agent dissolved in a layer of adhesive. A release liner is removably attached over the layer of adhesive, with the patch and the release liner together being sufficiently resilient so as to generate a spring force when displaced out of the flat configuration. The first and the second plies each being separable along the seal and displaceable out of the flat configuration. The spring force generated by the patch and the release liner being sufficient to overcome an adhesive force created by the adhesive between the patch and one of the plies. 122-. (canceled)23. A medicine system , comprising:1) first and second opposing flexible plies forming an enclosure;2) a seal, extending along at least a portion of a perimeter of the opposing plies with an enclosed cavity between the plies;3) first and second opposing tabs, formed by a portion of the respective first and second opposing plies which extend beyond the seal; a) a backing layer;', i) a salt of testosterone;', 'ii) methyltestosterone, androstenedione, adrenosterone, dehydroepiandrosterone, oxymetholone, fluoxymesterone, methandrostenolone, testolactone, pregnenolone, 17α-methylnortestosterone, norethandrolone, dihydrotestosterone, danazol, androsterone, nandrolone, stanozolol, ethylestrenol, oxandrolone, bolasterone, mesterolone, testosterone propionate, testosterone cypionate, testosterone phenylacetate, testosterone enanthate, testosterone acetate, testosterone buciclate, testosterone heptanoate, testosterone decanoate, testosterone caprate, testosterone isocaproate and combinations thereof; and', 'iii) combinations thereof;, 'b) a compound selected from the group consisting of, 'c) an adhesive layer with an exposed perimeter, wherein the ...
Подробнее