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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 20223. Отображено 100.
05-01-2012 дата публикации

Prosthetic device and method of using in breast augmentation and/or breast reconstruction

Номер: US20120004723A1
Принадлежит: Allergan Inc

A method of using a biocompatible surgical knitted, silk scaffold device in a breast augmentation or in a breast reconstruction cosmetic or surgical procedure such as single-stage or two-stage breast reconstruction. In an aspect of the invention, the silk scaffold employs a knit pattern that substantially prevents unraveling and preserves the stability of the mesh or scaffold device, especially when the mesh or scaffold device is cut. An example scaffold device employs a knitted mesh including at least two yarns laid in a knit direction and engaging each other to define a plurality of nodes. The at least two yarns include a first yarn and a second yarn extending between and forming loops about two nodes. The second yarn has a higher tension at the two nodes than the first yarn. The second yarn substantially prevents the first yarn from moving at the two nodes and substantially prevents the knitted mesh from unraveling at the nodes.

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12-01-2012 дата публикации

High Energy Visible Light Filter Systems with Yellowness Index Values

Номер: US20120008217A1
Принадлежит: High Performance Optics Inc

The present invention relates to ophthalmic and non-ophthalmic systems with blue light filtering and Yellowness Index ranges. UV and IR filtering are also included. Industrial applications are also outlined in the invention.

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19-01-2012 дата публикации

Intraocular lens injector

Номер: US20120016374A1
Автор: Myoung Soo Han
Принадлежит: RET CO Ltd

Disclosed herein is an intraocular lens injector for inserting an intraocular lens into an eye, the intraocular lens injector including: a cylindrical cylinder, into which a plunger for passing the intraocular lens to be guided into the eye is inserted; a connection block having a C-shaped longitudinal cross-section and integrally formed at the front end of the cylinder; a cartridge, which is connected to the connection block and includes first and second wing portions, which are folded with respect to each other, first and second receiving grooves formed at the connection portion of the first and second wing portions and having a semicircular longitudinal cross-section, and a truncated conical guide portion, which extends from the second receiving groove in the lateral direction and includes a guide passage having a circular cross-section corresponding to the shape of the assembled first and second receiving grooves; and an engagement member having a circular cross-section corresponding to the shape of the assembled first and second receiving grooves and maintaining the intraocular lens in a folded state.

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26-01-2012 дата публикации

Dual Mode Automated Intraocular Lens Injector Device

Номер: US20120022548A1
Автор: Jaime Zacharias
Принадлежит: Alcon Research LLC

An IOL injector device allows for both powered and manual delivery of an IOL. The injector has a tubular housing. A plunger is longitudinally disposed within the housing and has first and second ends. The first end is disposed towards the front end of the housing. A drive system is coupled to the housing. The drive system causes longitudinal translation of the plunger along the primary axis of the housing. A normally engaged clutch system is coupled to the drive system. The normally engaged clutch system allows manual disengagement of the drive system. A knob coupled to the plunger allows for manual operation of the injector.

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09-02-2012 дата публикации

Methods for applying a skin graft

Номер: US20120035619A1
Принадлежит: Momelan Technologies Inc

The present invention generally relates to methods for applying a skin graft. Methods of the invention involve harvesting an epidermal skin graft, and applying the epidermal skin graft to a recipient site such that the basal layer of the skin graft makes direct contact with the recipient site.

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09-02-2012 дата публикации

Intravitreous self adaptive stent

Номер: US20120035738A1
Автор: Rongping Dai
Принадлежит: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Disclosed herein are devices, methods and kits for a stent for treating an eye, comprising a flexible material, wherein the stent is self adaptive to a dimension of a vitreous cavity in the eye.

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16-02-2012 дата публикации

Apparatus and Method for Capsule Formation in Tissue

Номер: US20120041393A1
Принадлежит: CARDIOPOLYMERS Inc, HENRY FORD HEALTH SYSTEM

Capsules, emplacement apparatus, and associated methods for establishing a capsule within tissue are described herein. The emplacement apparatus may be catheter-based or implemented in a handheld unit. The emplacement apparatus serves to introduced an encapsulating membrane in a collapsed condition into the tissue, and then to expand the encapsulating membrane within the tissue into a capsule by injection of fill material into the encapsulating membrane. Other than being capable of injection through the emplacement apparatus, the fill material may be selected and formulated to achieve such mechanical and biological properties within the encapsulating membrane after injection as are desired to achieve the therapeutic effect sought for the patient. Mechanically, the fill material within the encapsulating membrane after injection may be a liquid, a semi-solid such as a gel, or a solid such as a cross-linked polymer. The fill material may or may not be sealed within the encapsulating membrane.

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01-03-2012 дата публикации

Flow regulating implant, method of manufacture, and delivery device

Номер: US20120053505A1
Автор: Ira Yaron, Orit Yarden
Принадлежит: Optonol Ltd

An implant includes a tube for permitting fluid flow. A flow controlling rod may be inserted within the tube passage. One or more holes around the circumference of the tube may be selectively permanently or temporarily occluded to give desired flow characteristics. A delivery device for implanting the implant may include a central bore in which a retractable wire is located. The retractable wire penetrates a tube passage of the implant. After the implant is in position in the eye, the retention wire is retracted out of the implant. In a method for manufacturing an implant, two tubes of different diameters are utilized. The smaller tube fits inside the longitudinal bore of the larger tube. When the tubes are cut, the smaller tube forms the tube of the implant and the remaining portions of the larger tube form the retention projection and/or disk of the implant.

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08-03-2012 дата публикации

Intraocular lenses with interlenticular opacification resistance

Номер: US20120059466A1
Принадлежит: Individual

The present invention is directed to an intraocular lens, an intraocular lens system and a method of producing and/or implanting the lens or system in an eye wherein at least one intraocular lens includes a coating that aids in resisting opacification (e.g., posterior capsule opacification (PCO), interlenticular opacification (ILO) or the like). The material of the coating is preferably hydrophilic or super-hydrophobic.

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08-03-2012 дата публикации

Transplantation device

Номер: US20120059488A1
Автор: Shigeto Shimmura
Принадлежит: KEIO UNIVERSITY

The present invention is intended to provide a transplantation device which can transplant a graft into a layered tissue easily and without damaging the graft or a tissue around the transplantation site. A transplantation device ( 1 ) according to the present invention is a device for transplanting a graft to a living body, including a pair of flexible holding sheets ( 2,3 ) for holding the graft, wherein each of the holding sheets has a grip part for gripping the holding sheet, and the graft held between the holding sheets is exposed by pulling the paired grip parts ( 4,5 ) in directions away from the graft. By using the transplantation device, a graft can be transplanted into a layered tissue easily and without damaging the graft or a tissue around the transplantation site.

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22-03-2012 дата публикации

Artificial eye and method of manufacture

Номер: US20120071971A1
Автор: Roger A. Martin
Принадлежит: MCKENZIE SPORTS PRODUCTS Inc

An artificial eye comprises a transparent cup-shaped body member having a substantially concave inner surface and a substantially convex outer surface. The body member includes a pupil portion at the center, a substantially annular iris portion abutting the peripheral edge of the pupil portion for defining a boundary between the pupil portion and the iris portion, and at least one groove formed in the concave inner surface of the iris portion of the body member. The grooves are visible through the iris portion for reflecting light through the body member.

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29-03-2012 дата публикации

Accommodating intraocular lens

Номер: US20120078364A1
Автор: Donald C. Stenger
Принадлежит: Individual

An Accommodating Intraocular Lens (AIOL) is disclosed herein, that is comprised of a flexible optic and a flexible haptic rim that conforms to the human eye capsule. The spherical or custom shape of the optic is engineered to be maintained during accommodation through the mechanical/optic design of the implant and the interaction between the implant and the naturally occurring position and actuating forces applied through ciliary muscles/zonules/and capsule as the brain senses the need to increase the diopter change or magnification when an object of fixation approaches the eye. The axial relocation or position of the AIOL may also be further adjusted anatomically to further improve the affect needed to achieve improved accommodation. Optionally, the Accommodating Intraocular Lens (AIOL) is foldable or injectable for delivery of the lens into the eye.

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29-03-2012 дата публикации

Columellar strut for nasal tip support

Номер: US20120078367A1
Принадлежит: Ethicon Inc

Novel bioabsorbable, columellar strut implants are disclosed. The struts are useful in rhinoplasty and nasal reconstruction surgical procedures. The devices have opposed lateral sides connected to a spine member to form a tissue-receiving channel.

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10-05-2012 дата публикации

System and device for correcting hyperopia, myopia and presbyopia

Номер: US20120116505A1
Принадлежит: Individual

The present invention includes an ophthalmic device and system of mounting for correcting hyperopia, myopia and presbyopia. The present invention includes a limbus ring mountable in an encircling relation to a central optic zone of a cornea on a limbus annulus surrounding the cornea. In the limbus ring defines a substantially annular toroid defining a first average diameter that is selectable and has a hydrophilic coating disposed thereon. The inner radius of the limbus ring is selectable such that, upon mounting on the limbus annulus, the limbus ring causes the limbus annulus to contract or expand thereby causing the curvature of the cornea and the eye length to increase or decrease. The mounting system of the present invention is adapted to receive a limbus ring and further adapted to selectively place the limbus ring on a limbus annulus.

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10-05-2012 дата публикации

Breast implant system

Номер: US20120116509A1
Автор: Peter Forsell
Принадлежит: MILUX HOLDING SA

A breast implant system comprises at least one casing ( 3, 4 ) with a flexible outer shape for implantation in a patient's body so as to form part of a breast implant ( 10 ) and further comprises at least one first element ( 1 ) contained in the casing and optionally at least one second element ( 2 ) also contained in the casing. The first and second elements are either displaceable within the casing and/or their volume can be changed in order to change the shape and/or size of the breast implant. A reservoir (R) comprising a lubricating fluid is connected to the casing so as to allow lubricating fluid to be supplied to and removed from the casing in order to reduce surface friction between adjacent elements and/or between the casing and the elements before the shape of the breast implant is changed.

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17-05-2012 дата публикации

High Performance Selective Light Wavelength Filtering

Номер: US20120120515A1
Принадлежит: High Performance Optics Inc

A system may be provided that comprises a substrate and a selective light wavelength filter that selectively blocks between 5 and 50% of light having a wavelength at or near 400-460 nm. The system may comprise any one of, or some combination of: a window, automotive glass, a light bulb, a flash bulb, fluorescent lighting, LED lighting, instrumentation, a display system, a visual system, a television, or a computer monitor.

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17-05-2012 дата публикации

Therapeutic Breast Implants

Номер: US20120123535A1
Автор: Kathia Alejandro
Принадлежит: Individual

A breast implant and process to optimize the treatment of breast cancer patients that offers more effective alternatives in breast reconstruction and simultaneously administers regional therapies in order to minimize the possibility of local recurrences. The breast implant comprises an inner porous core contained by an elastic holding layer with a system of tubes and conducts within it covered with biodegradable chemotherapeutic and attaching layers.

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24-05-2012 дата публикации

Method for reconstruction and augmentation of the breast

Номер: US20120130490A1
Принадлежит: Individual

The invention provides a method for manufacturing a breast prosthesis, which method comprises the determination of existing contours of a breast of an individual in an upright position using magnetic resonance imaging (MRI) and/or 3D scanning with ultrasound (US), laser or photography, the planning of a moulage or virtual moulage using a computer-assisted modeling software, with or without a 3D visualization of a result to be expected, and the manufacturing of a customized breast prosthesis based on said moulage or said virtual moulage. The invention also provides for methods of breast reconstruction and/or augmentation.

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07-06-2012 дата публикации

Process for texturing materials

Номер: US20120142798A1
Принадлежит: Allergan Inc

Provided are methods for making textured implantable materials made from two part RTV silicone foams and having a desired color or tone without the need for dyes or colorants.

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07-06-2012 дата публикации

Corneal inlay with nutrient transport structures

Номер: US20120143325A1
Принадлежит: Acufocus Inc

Corneal inlays and masks and methods of improving vision of a patient with corneal inlays and masks are provided. Masks with an aperture can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. For example, a mask can have an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion, such as a clear lens or aperture. This provides an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The mask may also include nutrient transport structures that provide nutrient flow through mask to prevent nutrient depletion. These nutrient transport structures can be configured to concentrate nutrient transmission near a center region of the mask to provide more nutrient flow near the center region.

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07-06-2012 дата публикации

Variable cohesive gel form-stable breast implant

Номер: US20120143328A1
Принадлежит: Allergan Inc

A variable cohesive gel form stabilizing implant is provided for augmentation or reconstruction of the breast. The prosthesis includes a shell filled with a gel having variations in cohesiveness to maintain stable form, shape, and dimension after surgical implantation.

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14-06-2012 дата публикации

Contra-Aspheric Toric Ophthalmic Lens

Номер: US20120147321A1
Автор: Valdemar Portney
Принадлежит: Valdemar Portney

An ophthalmic toric lens to be worn on an eye or implanted inside of an eye, the lens includes an anterior surface, a posterior surface, and a toric shape formed into one of the anterior and posterior surfaces, the toric shape comprising two non-spherical principle meridians each having a region within an annular area of optical zone and the region of one principle meridian being configured for producing a longitudinal ray aberration of a different sign than a longitudinal ray aberration sign from the region of another principle meridian.

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14-06-2012 дата публикации

Synthetic graft

Номер: US20120148543A1
Автор: Che Connon
Принадлежит: Individual

The present invention relates to the use of a plastically-compacted collagen gel as a substrate for the growth of corneal cells, particularly limbal corneal epithelial stem cells. Cells grown on such a substrate can be cultured to produce artificial ocular epithelia which can be used in ocular toxicity testing or for transplantation.

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14-06-2012 дата публикации

Interfacial refraction accommodating lens (iral)

Номер: US20120150292A1

This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any other accommodative forces. Lenses of this invention are generally referred to as interfacial, i.e., lens properties being defined as the interface of two liquids having different refractive indices, refractive accommodating lenses (IRAL).

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21-06-2012 дата публикации

Intraocular lens transfer case

Номер: US20120158007A1
Принадлежит: Individual

An intraocular lens (IOL) transfer case for transferring an IOL to an injection cartridge includes a lens holder for holding the IOL. The lens holder includes a bore. Folding members within the lens holder are configured to fold the IOL into a partially folded position when the IOL is slid through the bore across the folding members. The IOL transfer case also includes an interface configured to removably connect to an injection cartridge. The interface is positioned to deliver the IOL in the partially folded position within the injection cartridge when the interface is connected to the injection cartridge. The IOL transfer case also includes a plunger connected to the lens holder and configured to push the IOL in the partially folded position through the bore to deliver the IOL into the injection cartridge.

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21-06-2012 дата публикации

Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration

Номер: US20120158132A1
Принадлежит: AMO Groningen BV

An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition. The empirically derived regression calculation includes at least a product of the corneal spherical aberration with an empirically derived corneal spherical aberration constant, and a mathematical indication of the at least one biometric parameter or one of the paraxial regression formulas commonly used in clinical practice to calculate IOL power in normal patients.

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02-08-2012 дата публикации

Method of making ophthalmic devices and components thereof from hydrophobic acrylic (ha) polymers with reduced or eliminated glistenings

Номер: US20120196951A1
Автор: Khalid Mentak
Принадлежит: Key Medical Technologies Inc

This invention relates to the fields of polymer chemistry, materials science and ophthalmology. More particularly it relates to optical components and method(s) of preparing same from hydrophobic acrylic (HA) monomer(s) that exhibit reduced or eliminated glistenings when implanted in a patient's eye. The method of this invention uses a mixture of one or more low temperature initiators (LTI) combined with one or more high temperature initiators (HTI), to polymerize one or more HA monomers to produce an optical HA polymer which, when used to manufacture an optical component and implanted as with an intraocular lens (IOL), exhibit reduced glistenings to the patient.

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02-08-2012 дата публикации

Coupling apparatus

Номер: US20120197066A1
Принадлежит: Sentient Medical Ltd

Coupling apparatus for coupling an implantable element to the round window membrane. The apparatus comprises engagement means in the form of a clip or a filler material for engaging the bone surface within the round window niche. This supports the apparatus in the region of the round window membrane.

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09-08-2012 дата публикации

Ophthalmic Lens with Multiple Phase Plates

Номер: US20120200823A1
Принадлежит: Abbott Medical Optics Inc

An ophthalmic lens for providing a plurality of foci includes an optic having an anterior surface, a posterior surface, and an optical axis. The ophthalmic lens has a first region and a second region. The first region has a first refractive optical power and includes a first base curvature having a finite radius of curvature and a first phase plate having at least one diffraction order with a diffractive optical power. The first region is configured for forming a first focus and a second focus. The second region has a second refractive optical power and includes a second base curvature having a finite second radius of curvature that is different from the first radius of curvature and a second phase plate having at least one diffraction order with a diffractive optical power.

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09-08-2012 дата публикации

Method and apparatus for centration of an ocular implant

Номер: US20120203239A1
Принадлежит: Acufocus Inc

This application describes apparatuses and techniques for identifying and marking a position corresponding to the intersection of a patient's line of sight with the anterior surface of the human cornea to aid centration of an ocular implant. The apparatus can include a first optical subsystem configured to project a first light through an aperture and along an instrument axis such that the patient will observe an annulus around a disc when the patient's visual axis is substantially collinear with the instrument axis and the patient will not observe the annulus when the visual axis is not substantially collinear with the instrument axis. The apparatus may also include a second optical subsystem configured to project a second light along the instrument axis such that the second light appears to a clinician to be an annulus around the first light.

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09-08-2012 дата публикации

Intraocular implant

Номер: US20120203337A1

An intraocular implant ( 1 ) including an optical portion ( 2 ) and a haptic portion ( 3 ), the haptic portion including two diametrically opposite haptic systems ( 3 a, 3 b ), characterized in that each of the haptic systems ( 3 a, 3 b ) includes two substantially identical haptics ( 4, 5 ) interconnected by their respective distal ends ( 4 a, 5 a ), the respective proximal ends ( 4 b, 5 b ) of the two haptics ( 4, 5 ) being connected to the optical portion ( 2 ) via a stalk ( 6 ), the width of each of the haptics ( 4, 5 ) decreasing continuously all along the haptic toward the distal end ( 4 a, 5 a ).

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23-08-2012 дата публикации

Hair restoration surgery

Номер: US20120215231A1
Автор: Carlos K. Wesley
Принадлежит: Individual

A surgical apparatus includes an elongated member ( 1 ), a dissection module ( 10 ), and an extraction module ( 701 ). The dissection module is removably attachable to a first end of the elongated member and includes a tissue separating device ( 10 ). The extraction module is removably attachable to the first end of the elongated member and includes a suction port and a tissue removal implement ( 13,14 ) disposed within the suction port.

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30-08-2012 дата публикации

Retinal prosthesis with efficient processing circuits

Номер: US20120221103A1
Принадлежит: Nano Retina Inc

A medical device includes an array of electrodes, configured for implantation in contact with tissue in an eye of a living subject. Driver circuitry is configured to drive the electrodes in an alternating pattern, such that different groups of the electrodes are driven to stimulate the tissue during different, predetermined respective time periods. A power sensor, may be coupled to deactivate a first group of the electrodes when the available electrical power drops below a predetermined threshold, while a second group of the electrodes remains active. Other embodiments are also described.

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30-08-2012 дата публикации

Prosthetic device and method of manufacturing the same

Номер: US20120221104A1
Принадлежит: Allergan Inc

An implantable device for use in tissue and ligament repair comprising at least one knitted section and at least one single continuous fiber traversing the at least one knitted section, the at least one single continuous fiber forming a plurality of traverses extending through the at least one knitted section. The implantable device may comprise at least one single continuous silk fiber. The implantable device is suitable for use in a variety or reconstructive or support applications such as breast reconstruction, mastopexy, breast augmentation revision, breast augmentation support, standard breast augmentation, chest wall repair, organ support, body contouring, abdominoplasty, facial reconstruction, hernia repair, and pelvic floor repair.

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06-09-2012 дата публикации

Devices and methods for reshaping cartilage structures

Номер: US20120226307A1
Принадлежит: NUMENA MEDICAL Corp

A networked system in which the majority of data bypass the server ( 101 ) to improve end-to-end performance of network access by achieving higher throughput between the network ( 130 ) and storage system ( 110 ). The apparatus consists of a network interface ( 120 ), server computer interface ( 240 ), and storage interface ( 250 ); and a switching element ( 201 ) and a high-layer protocol decoding and control unit ( 205 ). Incoming traffic is decoded and compared against a routing table. If there is a matching entry, it will be routed to the storage interface or sent to the server for further processing by default. The routing table entries are set up based on the initial nature of the applications. Subsequently, barring any changes or errors, there will be no data exchange between the server and the device. There may also be a speed matching funcion between the network and storage, load balancing function for servers, and flow control for priority and QOS purposes.

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13-09-2012 дата публикации

Implant with a visual indicator of a barrier layer

Номер: US20120232652A1
Принадлежит: Individual

An implantable soft tissue prosthesis device comprising a silicone elastomer-shell filled with silicone gel or liquid, which among the layers that constitute its shell includes a barrier layer formed of a low permeability silicone, which impedes the bleeding or diffusion of the silicone gel from the inside of the implant to its surroundings through the shell. This barrier layer is given a coloration different to the other layers of the shell, making it visible in the finished product. The coloration of the barrier layer gives the fabricator of the implant as well as to medical personnel, the possibility to identify the presence of the barrier layer and its homogeneity, improving the safety of the device.

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20-09-2012 дата публикации

Vision Modification with reflected image

Номер: US20120236257A1
Принадлежит: Individual

Various embodiments of methods and systems for improving and enhancing vision are disclosed. Adjustable lenses or optical systems may be used to provide adaptive vision modification. In some embodiments, vision modification may be responsive to the current state of the user's visual system. Certain embodiments provide correction of the subject's near and far vision. Other embodiments provide enhancement of vision beyond the physiological ranges of focal length or magnification.

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27-09-2012 дата публикации

Corneal implant for refractive correction

Номер: US20120245683A1
Принадлежит: Acufocus Inc

A corneal implant adapted for implantation between layers of a cornea to focus an image on a retina of an eye includes an inlay, an outer perimeter, and a clear central region capable of refracting light to compensate for a refractive error of an eye. The inlay also has an annular opaque region comprising a plurality of holes or otherwise being adapted to transport nutrients. The annular opaque region extends from the outer circumference of the inlay to the clear central portion. The opaque region extends over a minority of the surface area of the implant. The anterior and posterior surfaces of the inlay are configured to abut adjacent layers of the cornea.

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04-10-2012 дата публикации

Modulating buttress saline mammary prosthesis including limpet fill port

Номер: US20120253460A1
Автор: Walter J. Ledergerber
Принадлежит: Individual

An implantable mammary prosthesis includes a limpet buttress fill port structure. The fill port structure preferably comprises a shell, the shell including an opening, a compartment interior to the shell adapted to contain a filler. The limpet buttress is generally cup-shaped, and is disposed within the shell. The limpet buttress is preferably attached to the shell adjacent the opening to form a fluidic seal, optionally via a sealing flange. The limpet buttress may include one or more ribs, such as to provide structural support to the limpet buttress. Preferably, a reservoir is disposed external to the shell.

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18-10-2012 дата публикации

Correction of higher order aberrations in intraocular lenses

Номер: US20120262670A1
Принадлежит: Mutlu Karakelle, Xiaoxiao Zhang, Xin Hong

In one aspect, the present invention provides a method of designing an intraocular lens (IOL) to address variations of at least one ocular parameter in a population of patient eyes. The method can include establishing at least one eye model in which the ocular parameter can be varied over a range exhibited by the population. The eye model can be employed to evaluate a plurality of IOL designs in correcting visual acuity for eyes in the patient population. An IOL design that provides a best fit for visual performance over at least a portion of the parameter range can then be selected.

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01-11-2012 дата публикации

Systems and Methods for Determining Intraocular Lens Power

Номер: US20120274895A1
Принадлежит: AMO Groningen BV

The present invention relates to devices, systems and methods for determination or selection of a lens power based on the postoperative vitreous length of an eye. The combined measurements of VL pre , ACD pre , AL, and/or LT are highly predictive in calculating the postoperative vitreous length, from which the position of the implanted intraocular lens or optic can be derived, and then selection of the appropriate lens power.

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01-11-2012 дата публикации

Lightweight breast implant material

Номер: US20120277860A1
Принадлежит: Individual

A prosthetic implant material for use in a prosthetic implant, comprising a gel and optionally a gas.

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08-11-2012 дата публикации

Ossicular Prosthesis with Stabilizer and Method of Use with Intact Stapes

Номер: US20120283827A1
Принадлежит: Enteroptyx

A system is provided for stabilized total ossicular replacement in a middle ear having an intact stapes with a capitulum and a footplate. The system includes an ossicular replacement prosthesis including with elongate shaft and a head coupled to the shaft, and a stabilizer that couples the prosthesis to the stapes. The stabilizer has a first portion with a first opening and a second portion with a second opening, said first opening sized to stably engage the shaft of the prosthesis, and said second opening sized to stably engage the capitulum. When the shaft and capitulum are engaged they are retained in an side-by side configuration. The stabilizer may be constructed of an elastic polymer, an elastic metal alloy, a plastic material or a shape memory material.

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29-11-2012 дата публикации

Flush patch for elastomeric implant shell

Номер: US20120303120A1
Автор: David J. Schuessler
Принадлежит: Allergan Inc

An elastomeric prosthetic breast implant is provided having a shell and a patch forming a flush interface with the shell and no sudden surface steps on both interior and exterior surfaces of the shell.

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13-12-2012 дата публикации

Electrode impedance spectroscopy

Номер: US20120316454A1
Автор: Paul Carter
Принадлежит: Cochlear Ltd

Aspects of the present invention are generally directed to impedance spectroscopy in an active implantable medical device (AIMD) comprising a component with one or more electrodes. In an embodiment, the AIMD applies a signal at a plurality of frequencies using one or more of the electrodes. Measurements are then obtained for the applied signal to determine impedance(s) at the applied frequencies of the tissue in which the electrodes are located.

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03-01-2013 дата публикации

Artificial skin

Номер: US20130006355A1
Принадлежит: Shiseido Co Ltd

The present invention relates to a method for producing artificial skin, comprising: adding a matrix metalloproteinase inhibitor and a heparanase inhibitor to an artificial skin formation culture medium comprising human epidermal keratinocytes and human dermal fibroblasts, culturing the cells in the artificial skin formation culture medium, and forming artificial skin.

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17-01-2013 дата публикации

All-purpose wig, method for fitting wig, and customized wig

Номер: US20130014776A1
Принадлежит: Propia Co Ltd

An all-purpose wig has a base including an ultrathin and moisture permeable film--shaped material, and hair materials adhered to one surface of the base. A first adhesion layer includes an adhesion agent having comparatively strong adhesion and a comparatively large degree of gelling. A second adhesion layer includes an adhesion agent having comparatively weak adhesion and a comparatively small degree of gelling. The first adhesion layer and the second adhesion layer are provided adjacent to each other with a tank layer therebetween. A first release layer is attached peelably to the whole surface of the second adhesion layer on the side that is fit to the skin, and a second release layer is applied peelably to the first adhesion layer and is layered on a portion of the surface between the first adhesion layer and the tank layer. The layers are layered in order, forming a flat surface.

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24-01-2013 дата публикации

Porous materials, methods of making and uses

Номер: US20130023987A1
Принадлежит: Allergan Inc

The present specification discloses porous materials, methods of forming such porous materials, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.

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31-01-2013 дата публикации

Pre-stressed haptic for accommodating intraocular lens

Номер: US20130030525A1
Принадлежит: Abbott Medical Optics Inc

An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. The haptic may be pre-stressed before the optic is placed within it. After such placement, the pre-stress may be relieved, and the haptic may produce stress in the optic. The pre-stress may produce a radial tension or a radial compression in the optic. Alternatively, once the optic is placed within the haptic, both may undergo a process that changes the size and/or shape of one with respect to the other, causing a stress within the optic. This process may produce a radial tension or a radial compression in the optic. The haptic may include an annular ring having outer and inner diameters that may depend on the stiffness of the haptic.

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31-01-2013 дата публикации

Engineered Tissue Implants And Methods Of Use Thereof

Номер: US20130030548A1
Автор: Jian Ling
Принадлежит: Southwest Research Institute SwRI

A engineered tissue implant comprising a perfusion chamber formed with a biocompatible flexible tubular member having a wall defining an internal fluid flow passage and a porous scaffold within the fluid flow passage of the tubular member, the porous scaffold arranged such that, in a presence of a perfusion fluid, the perfusion fluid will flow through the porous scaffold and be inhibited from flow between the porous scaffold and the wall of the tubular member. The engineered tissue implant may be understood as a transplantable cell construct or as an implantable bioreactor for cell growth both in vitro and/or in vivo. A method to provide tissue for reconstruction may comprise forming the engineered tissue implant containing a scaffold, introducing and seeding cells to the scaffold, introducing a perfusion fluid to the scaffold which flows through the fluid flow passage and scaffold, proliferating the cells within the scaffold and forming blood vessels within the scaffold. This may be followed by transplanting the engineered tissue implant in vivo where nutrition and oxygen are provided to support the preloaded cells.

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07-02-2013 дата публикации

Optical Element for Correcting Color Blindness

Номер: US20130033776A1
Принадлежит: Nitto Denko Corp

Described herein are devices, compositions, and methods for improving color discernment.

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14-02-2013 дата публикации

Application and network-based long poll request detection and cacheability assessment therefor

Номер: US20130041974A1
Принадлежит: Seven Networks Inc

Systems and methods for application and network-based long poll request detection and cacheability assessment therefore are disclosed. In one aspect, embodiments of the present disclosure include a method, which may be implemented on a distributed proxy and cache system, including, determining relative timings between a first request initiated by the application, a response received responsive to the first request, and a second request initiated subsequent to the first request also by the application. The relative timings can be compared to request-response timing characteristics for other applications to determine whether the requests of the application are long poll requests.

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28-02-2013 дата публикации

Intraocular lens (iol)

Номер: US20130053955A1
Автор: Gene Currie
Принадлежит: Individual

An improved intraocular lens, for example, an accommodating intraocular lens including a lens optic or lens optic portion provided with a light window.

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07-03-2013 дата публикации

Optical Element for Correcting Color Blindness

Номер: US20130057824A1
Принадлежит: Nitto Denko Corp

Described herein are devices, compositions, and methods for improving color discernment.

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07-03-2013 дата публикации

System, ophthalmic lens, and method for extending depth of focus

Номер: US20130060330A1
Принадлежит: AMO Groningen BV

System, ophthalmic lens, and method for extending depth of focus includes an optic having a clear aperture disposed about a central axis. The optic includes a first surface and an opposing second surface. The first and second surfaces are configured to introduce an asymmetric aberration to the eye while maintaining the in-focus visual acuity.

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14-03-2013 дата публикации

MINIMALLY INVASIVE TISSUE SUPPORT

Номер: US20130066423A1
Принадлежит:

Embodiments of apparatus and methods for tissue lifting, or for correcting a ptosis condition caused by tissue stretching, are described. In some embodiments a tissue is supported by a support member. In some embodiments, tension is applied to a support member through at least one suspension member. The described embodiments provide examples of methods and apparatus effective for use in lifting or otherwise applying tension to various tissues, including tissues of the breast, buttock, thigh, arm, abdomen, neck and face. 1. A device , for use in supporting a tissue in a patient's body , comprising;a support member, adapted to engage at least a portion of a tissue, the support member comprising a first end and a second end, the support member further comprising a plurality of support elements; andfirst and second suspension members, the first suspension member being coupled to the first end of the support member, the second suspension member being coupled to the second end of the support member;wherein at least one of the first and second suspension members is configured to be secured to a location in the patient's body;wherein the plurality of support elements is configured to distribute a load, from the tissue engaged by the support member, imposed on the support member; andwherein at least one of the first and second suspension members is configured to transmit a force through the support member, the force effective to move the engaged portion of the tissue from a first position to a second position.2. The device of claim 1 , wherein the first suspension member is coupled to each support element at a first end of each support element claim 1 , and the second suspension member is coupled to each support element at a second end of each support element.3. The device of claim 1 , wherein the second position is superior to the first position.4. The device of claim 1 , wherein the second position is at least one of posterior claim 1 , medial claim 1 , and lateral claim 1 ...

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21-03-2013 дата публикации

Conformable Therapeutic Shield for Vision and Pain

Номер: US20130070200A1
Принадлежит: Nexis Vision Inc

A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

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21-03-2013 дата публикации

MOLECULAR FILMS FOR HYDROPHOBIC IMPLANT SURFACES

Номер: US20130071590A1

Compositions are disclosed containing a solvated viscoelastic polymeric gel diluted into an ionically conductive aqueous solution which can be usefully applied to any surface that is hydrophobic to act, for example, as an antifogging coating with minimal optical distortion and excellent transparency. The compositions can also be used as lubricious agents on medical implants, shunts, and surgical supplies to minimize tissue trauma, to maximize bio-compatibility, and to increase healing by enhancing better irrigation and flow in adjacent tissue. 1. A composition , comprising a mixture of: '(b) an ionically conductive aqueous solution;', '(a) a solvated viscoelastic polymeric gel, comprising a viscoelastic polymer having a molecular weight of between about 20,000 Da and about 4,000,000 Da; and'}wherein the volume ratio of (a) to (b) is between 1:1 and 1:10.2. The composition of claim 1 , wherein the composition is an emulsion.3. The composition of wherein the ionically conductive aqueous solution comprises at least 0.03% electrolytes.4. The composition of wherein the ionically conductive aqueous solution approximates the composition of human vitreous humor.5. The composition of wherein the solvated viscoelastic polymeric gel comprises a viscoelastic polymer having a molecular weight of between about 20 claim 1 ,000 Da and about 500 claim 1 ,000 Da.6. The composition of wherein the solvated viscoelastic polymeric gel claim 1 , comprising a viscoelastic polymer having a molecular weight of between about 20 claim 1 ,000 Da and about 200 claim 1 ,000 Da.7. The composition of wherein the solvated viscoelastic polymeric gel is homogenous.8. The composition of claim 1 , wherein the solvated viscoelastic polymeric gel comprises hydroxypropylmethylcellulose.9. The composition of comprising between 0.0003 wt % and 10 wt % of the viscoelastic polymer.10. A device claim 1 , consisting of {'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, '(b) a second layer comprising the ...

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21-03-2013 дата публикации

Using the light adjustable lens (lal) to increase the depth of focus by inducing targeted amounts of asphericity

Номер: US20130072591A1
Принадлежит: Individual

In general, the present invention relates to optical elements, which can be modified post-manufacture such that different versions of the element will have different optical properties. In particular, the present invention relates to lenses, such as intraocular lenses, which can be converted into aspheric lenses post-fabrication. Also, the present invention relates to a method for forming aspheric lenses post-fabrication.

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21-03-2013 дата публикации

Vision Prosthesis

Номер: US20130073038A1
Автор: Azar Dimitri
Принадлежит: Massachusetts Eye & Ear Infirmary

A vision prosthesis includes an intra-ocular lens system having a variable focal length; and a controller that causes a change in the focal length thereof. 1. A vision prosthesis comprising:an intra-ocular lens system having a variable focal length; anda controller for causing a change in the focal length thereof2. The vision prosthesis of claim 1 , further comprising a rangefinder for providing the controller with an estimate of a distance to an object-of-regard.3. The vision prosthesis of claim 1 , further comprising an actuator for receiving a signal from the controller to cause a change in the focal length of the intra-ocular lens system.4. The vision prosthesis of claim 1 , further comprising an actuator for changing an index of refraction of the intra-ocular lens system in response to a signal from the controller.5. The vision prosthesis of claim 1 , further comprising an actuator for mechanically changing the focal length of the intra-ocular lens system in response to a signal from the controller.6. The vision prosthesis of claim 1 , wherein the intra-ocular lens system comprises a chamber containing nematic liquid crystal.7. The vision prosthesis of claim 1 , wherein the intra-ocular lens system comprises:a first lens element;a second lens element moveable relative to the first lens element; anda motor coupled to the second lens element for moving the second lens element relative to the first lens element.8. The vision prosthesis of claim 2 , further comprising a transducer for detecting a stimulus from an anatomic structure within the eye and providing a signal indicative of the stimulus to the rangefinder.9. The vision prosthesis of claim 7 , further comprising a manual focusing control for enabling a patient to fine tune focusing of the lens.10. A vision-prosthesis comprising:an intra-ocular lens system having a variable focal length; andan actuator coupled to the intra-ocular lens system for causing a change in the focal length thereof11. The vision ...

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21-03-2013 дата публикации

Silicone Breast Implant Delivery

Номер: US20130073040A1
Автор: Preissman Howard E.
Принадлежит: KELLER MEDICAL, INC.

A tapered sleeve is provided that includes a hydrophilic coating on an inner surface. In use, the device is typically removed from sterile packaging and soaked to activate the lubricous properties of the coating. An implant (e.g., a pre-filled silicon breast implant) is introduced into a large end of the sleeve and extruded into a surgical pocket of minimal access incision size through a small-sized end of the device. 1. A method of inserting a pre-filled prosthesis into a surgical pocket with a tapered sleeve having a length and defining proximal and distal openings , the method comprising:fitting the sleeve into a basin in a compacted state, the basin at least partially filled with fluid;soaking the sleeve in the fluid to activate a lubricous coating adhered to an inner surface of the sleeve;removing the sleeve from the basin;inserting the prosthesis into the sleeve through the proximal opening;introducing the sleeve into the surgical pocket; andmanipulating the sleeve to conform to a shape of the prosthesis and apply pressure to direct the prosthesis along the length of the sleeve toward the distal opening, out of the distal opening and into the surgical pocket.2. A method of inserting a breast augmentation prosthesis into a surgical pocket within a breast with a tapered sleeve having a length and defining proximal and distal openings , the method comprising:hydrating the sleeve to lubricate an inner surface of the sleeve by activating a hydrophilic coating adhered to the sleeve;inserting the breast augmentation prosthesis into the sleeve through the proximal opening;introducing the sleeve into the surgical pocket within the breast; andmanipulating the sleeve to conform to a shape of the prosthesis and apply pressure to direct the prosthesis along the length of the sleeve toward the distal opening, out of the distal opening and into the surgical pocket within the breast.3. A method of preparing a delivery system for use in implanting a pre-filled prosthesis into ...

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04-04-2013 дата публикации

COMPOSITION AND METHOD OF PREPARATION OF POLYSACCHARIDE GEL-BASED ARTIFICIAL, BIODEGRADABLE SKIN SCAFFOLDS

Номер: US20130085571A1
Принадлежит:

An artificial, biodegradable skin scaffold includes a biodegradable polysaccharide hydrogel composition having a Young's modulus of at least about 10 MPa and, preferably, includes an additional biodegradable polysaccharide hydrogel composition with the two biodegradable polysaccharide hydrogel compositions contacting one another and the additional biodegradable polysaccharide hydrogel composition preferably having a Young's modulus of less than about 10 MPa. 133-. (canceled)34. An artificial , biodegradable skin scaffold , comprising:a biodegradable polysaccharide hydrogel composition having a Young's modulus of at least approximately 10 MPa.35. The artificial claim 34 , biodegradable skin scaffold according to claim 34 , wherein said biodegradable polysaccharide hydrogel composition is a first biodegradable polysaccharide hydrogel composition and further comprising a second biodegradable polysaccharide composition claim 34 , wherein said second biodegradable polysaccharide composition contacts said first biodegradable polysaccharide hydrogel composition.36. The artificial claim 35 , biodegradable skin scaffold according to claim 35 , wherein said second biodegradable polysaccharide hydrogel composition has a Young's modulus of less than 10 MPa.37. The artificial claim 34 , biodegradable skin scaffold according to claim 34 , wherein said biodegradable polysaccharide hydrogel composition comprises a polysaccharide selected from the group consisting of carrageenan claim 34 , xanthan gum claim 34 , locust bean gum claim 34 , konjac gum claim 34 , starch claim 34 , methyl cellulose claim 34 , carboxymethyl cellulose claim 34 , ethyl cellulose claim 34 , partially- or fully-deacetylated gellan claim 34 , carob gum claim 34 , agar claim 34 , poly(glucuronic acid) claim 34 , poly(galacturonic acid) and a combination thereof.38. The artificial claim 34 , biodegradable skin scaffold according to claim 34 , wherein said biodegradable polysaccharide hydrogel composition ...

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11-04-2013 дата публикации

Multifocal intraocular lens

Номер: US20130090730A1
Принадлежит: Abbott Medical Optics Inc

An intraocular lens for providing a subject with vision at various distances includes an optic having a first surface with a first shape, an opposing second surface with a second shape, a multifocal refractive profile, and one or more diffractive portions. The optic may include at least one multifocal diffractive profile. In some embodiments, multifocal diffractive and the multifocal refractive profiles are disposed on different, distinct, or non-overlapping portions or apertures of the optic. Alternatively, portions of the multifocal diffractive profiles and the multifocal refractive profiles may overlap within a common aperture or zone of the optic.

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18-04-2013 дата публикации

Ultraviolet light absorbing materials for intraocular lens and uses thereof

Номер: US20130096273A1
Принадлежит: Benz Research and Development Corp

A method for reducing the transmittance of ultraviolet radiation through an intraocular lens to 10% or less at 370 mm Additionally, a method for preventing the transmittance of at least 90% of ultraviolet radiation at 370 nm through a foldable intraocular lens comprising: (a) incorporating a monomer comprising a 4-(4,6-diphenyl-1,3,5-triazin-2-yl)-3-hydroxyphenoxy moiety into at least one polymer and (b) forming the polymer into a material suitable for use as an intraocular lens, wherein the monomer comprising a 4-(4,6-diphenyl-1,3,5-triazin-2-yl)-3-hydroxyphenoxy moiety comprises 0.10 to 0.15 weight percent of the overall dry polymer.

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18-04-2013 дата публикации

BODY PART SHAPED MOULD AND A METHOD FOR USING SUCH A MOULD

Номер: US20130096675A1
Принадлежит: Novoaim AB

The invention relates to a body part shaped mould, for example for creating a test breast, a customized bra or a test body part and a method for using such a mould. The mould is characterised in that it is made of a formstable material having a predetermined shape forming at least one cup. The cup is having a breast like appearance or a body part appearance with a specific size and shape and is adapted to be fitted to a patient's chest or corresponding body part, It is also adapted to be filled with a hardening mixture in a cavity formed between the mould and the chest or corresponding body part. An object of the present invention is to make it possible to try out a suitable size and shape of a breast or other body part, before an implantation is made. 11. A body part shaped mould , characterised in that the mould is made of an formstable material having a predetermined shape with at least one cup () having a breast like appearance or a body part appearance with a specific size and shape and is adapted to be fitted to a patients chest or corresponding body part and to be filled with a hardening mixture (M) in a cavity formed between the mould and the chest/natural breast or corresponding body part.211. A body part shaped mould according to claim 1 , wherein a first and a second cup ( claim 1 , ) are used as moulds.31111. A body part shaped mould according to claim 2 , wherein a first and a second cup ( claim 2 , ) are used as mould and the first and second cups ( claim 2 , ) are integrated so that they are forming one single mould.4114. A body part shaped mould according to claim 3 , wherein the first and second cups ( claim 3 , ) are joined together with flexible or versatile attachment means ().55. A body part shaped mould according to claim 1 , wherein the mould is adapted to be fitted to the patient's chest with a bra-like device () or an elastic wrap.623. A body part shaped mould according to claim 1 , wherein the edge () of the entire mould or each separate ...

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25-04-2013 дата публикации

Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods

Номер: US20130103143A1
Принадлежит: Refocus Group Inc

A system includes a scleral prosthesis and an insert. The scleral prosthesis includes an elongated body having a first free end and a second free end opposite the first end. A maximum width of the body at each end is wider than a maximum width of the body between the ends. The body includes multiple first portions that form the first end of the body and a part of the body between the ends. The first portions are separated lengthwise along a substantial portion of a total length of the body. The first portions are biased so that they maintain separation from one another without external interference but are configured to be pushed towards each other. The insert is configured to be placed between the first portions to maintain a separation of the first portions. The body and/or the insert could be formed using one or more magnetic materials.

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25-04-2013 дата публикации

SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY

Номер: US20130103144A1
Принадлежит: AAREN SCIENTIFIC INC.

A lens for placement in a human eye, such as an intraocular lens, has at least some of its optical properties modified with a laser. The lens preferably contains at least 5% by weight UV absorber so commercially feasible rates of manufacture can be achieved. The laser forms modified loci in the lens where the modified loci have a different refractive index than the refractive index of the material before modification. The same laser modification technique can be used on the cornea in situ. 1. A polymeric body sized for implantation in a human eye as an intraocular lens and containing at least 5% by weight UV absorber.2. The body of containing at least 10% by weight UV absorber.3. The body of comprising up to about 15% by weight UV absorber.4. The body of sufficiently foldable for implantation in a human eye.5. The body of wherein the body has at least one haptic.6. The body of having opposed anterior and posterior surfaces claim 1 , wherein at least one of the surfaces is substantially convex or substantially concave.7. The body of having a glass transition temperature equal to or less than 37° C.8. The body of having a glass transition temperature of less than 20° C.9. The body of comprising at least about 150 ppm by weight of yellow dye.10. The body of comprising at least about 500 ppm by weight yellow dye.11. The body of comprising up to about 1000 ppm by weight of yellow dye.12. A method for modifying the optical properties of a polymeric lens sized for placement in a human eye claim 9 , the lens having an anterior surface and a posterior surface claim 9 , the method comprising the step of modifying loci of the lens with a laser beam claim 9 , the modified loci having a different refractive index than the material before modification claim 9 , wherein the laser beam travels at a rate of at least 40 μm per second.13. The method of wherein the laser beam travels at a rate of at least 50 millimeters per second.14. The method of wherein the lens contains at least 5% ...

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25-04-2013 дата публикации

GONIO LENS SYSTEM WITH STABILIZATION MECHANISM

Номер: US20130103145A1
Принадлежит:

This disclosure relates generally to methods and devices for use in viewing and positioning an eye with a gonio lens system, such as during ocular exams and ocular surgeries. Some embodiments of the gonio lens system can include a gonio lens for viewing one or more tissues and structures of the eye. In addition, the gonio lens system can include one or more positioning features for controlling movement positioning of the eye. 1. A gonio lens system , comprising:a handle;a gonio lens; anda stabilization mechanism configured to couple the gonio lens to the handle, the stabilization mechanism further configured to allow the gonio lens to move relative to the handle.2. The system in claim 1 , wherein the stabilizing mechanism is further configured to couple one or more positioning features to the handle.3. The system in claim 2 , wherein the stabilization mechanism is configured to allow the positioning features to rotate relative to the handle and stabilize the positioning features relative to the eye.4. The system in claim 2 , wherein the positioning features include a stabilization bracket having one or more protrusions for positioning on the eye.5. The system in claim 4 , wherein the protrusions include at least one of a rounded shape and a surface feature for controlling movement of the eye.6. The system in claim 1 , wherein the stabilization mechanism includes a lens belt secured to at least a part of the gonio lens claim 1 , with the lens belt including a pair of extruding pins coupled to a pair of slots extending along a part of a lens bracket.7. The system in claim 6 , wherein the lens bracket is pivotally mounted to a support of a stabilization bracket claim 6 , with the stabilization bracket pivotally mounted to a bracket extending from a distal end of the handle.8. The system in claim 7 , wherein at least one of the lens bracket claim 7 , stabilization bracket and stabilizing bracket is U-shaped.9. The system in claim 6 , wherein the lens bracket includes a ...

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25-04-2013 дата публикации

Accommodating Intraocular Lenses and Methods of Use

Номер: US20130103146A1
Принадлежит:

Accommodating intraocular lenses containing a flowable media and their methods of accommodation. 1. An accommodating intraocular lens , comprising:an optic portion and a peripheral non-optic portion, the intraocular lens sized and configured to be implanted within a patient's eye, wherein the optic portion comprises an anterior lens element, a posterior lens element, and an optical axis; anda substantially nondeformable body defining an aperture, wherein the optical axis passes through the anterior lens element, the aperture, the posterior lens element, and a flowable media disposed between the anterior element and the posterior element,wherein the aperture is adapted such that an increase in pressure in the flowable media causes a change in power of the lens.2. The accommodating intraocular lens of claim 1 , wherein an increase in pressure in the flowable media causes a deformation of an optical interface of the intraocular lens claim 1 , which causes the change in power of the intraocular lens.3. The accommodating intraocular lens of claim 1 , wherein the anterior lens element is deformable in response to the increase in pressure in the flowable media.4. The accommodating intraocular lens of claim 1 , wherein the posterior lens element is deformable in response to the increase in pressure in the flowable media.5. The accommodating intraocular lens of claim 1 , wherein the optic portion and the peripheral portion are in fluid communication.6. The accommodating intraocular lens of claim 1 , wherein the flowable media is a fluid.7. The accommodating intraocular lens of claim 1 , wherein the aperture has a radial dimension that is smaller than a radial dimension of the anterior lens element.8. An accommodating intraocular lens claim 1 , comprising:an optic portion comprising an optical axis that passes through an anterior lens element, a posterior lens element, and a flexible intermediate element, wherein the flexible intermediate element is disposed between the ...

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25-04-2013 дата публикации

MASKED INTRAOCULAR IMPLANTS AND LENSES

Номер: US20130103147A1
Принадлежит: AcuFocus, Inc.

Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber. 1. A intraocular implant comprising:an implant body comprising a body material;a mask with an aperture positioned within the implant body, the mask comprises a plurality of holes that extend between a posterior surface and an anterior surface of the mask; andwherein the body material extends through the plurality of holes of the mask, and further wherein the plurality of holes are characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.2. The intraocular implant of claim 1 , wherein the plurality of holes are positioned at irregular locations.3. The intraocular implant of claim 1 , wherein a plurality of the holes comprise first hole size claim 1 , shape or spacing and at least another plurality of holes comprise a second hole size claim 1 , shape claim 1 , or spacing different from the first holes size claim 1 , shape claim 1 , or spacing.4. The intraocular implant of claim 1 , wherein a first plurality of the holes comprise first hole size claim 1 , a second plurality of the holes comprise a second hole size different form the third ...

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25-04-2013 дата публикации

Intraocular Lens

Номер: US20130103148A1
Автор: David P. Vanderbilt
Принадлежит: Bausch and Lomb Inc

An intraocular lens comprising: (a) monomeric units derived from at least one cationically polymerizable branched alkene monomer; (b) monomeric units derived from at least one cationically polymerizable monomer having a pendant benzocyclobutene group; and (c) a UV-absorbing benzotriazole component having the formula I.

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25-04-2013 дата публикации

PROSTHETIC FABRIC STRUCTURE

Номер: US20130103149A1
Принадлежит: ALLERGAN, INC.

Disclosed herein is an implantable prosthesis for breast augmentation or reconstruction procedures. The prosthesis comprises a biocompatible and biodegradable fabric structure comprising one or more individual yarns comprised of sericin-extracted native fibroin fibers, wherein the yarns are intertwined to produce the fabric structure. The fabric structure extends in at least a first dimension and has at least a first surface that is adapted to engage and support natural breast tissue and/or a prosthetic breast implant in a patient. Also disclosed are methods of supporting breast tissue or a breast implant in a patient by inserting the prosthesis between the skin of the patient and the breast tissue and/or implant within the patient. 1. A method of supporting breast tissue or a breast implant in a patient comprising:providing a biocompatible and biodegradable fabric structure comprising one or more individual yarns comprised of sericin-extracted native fibroin fibers, wherein the yarn(s) are intertwined to produce the fabric structure; andinserting the fabric structure between the skin of the patient and the breast tissue or the breast implant.2. The method of claim 1 , further comprising fastening the fabric structure to tissue surrounding the chest cavity of the patient.3. The method of claim 1 , further comprising fastening the fabric structure to soft tissue surrounding the breast tissue or the prosthetic breast implant.4. The method of claim 1 , further comprising fastening the fabric structure to a boney structure adjacent to the breast tissue or the prosthetic breast implant.5. The method of claim 1 , further comprising forming the fabric structure into a predefined shape adapted to conform to at least a portion of a region of natural breast tissue or a breast implant.6. The method of claim 1 , wherein the predefined shape is selected from the group consisting of a circular shape claim 1 , an oval shape claim 1 , a crescent shape claim 1 , a cup shape and an ...

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25-04-2013 дата публикации

DERMAL MICRO-ORGANS, METHODS AND APPARATUSES FOR PRODUCING AND USING THE SAME

Номер: US20130103151A1
Принадлежит: MEDGENICS MEDICAL ISRAEL LTD

Embodiments of the present invention provide Dermal Micro-organs (DMOs), methods and apparatuses for harvesting the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. Exemplary embodiments of the invention provide a genetically modified dermal micro-organ expressing at least one recombinant gene product. Some embodiments of the invention provide methods and apparatuses for implanting a genetically modified DMO. 2. The apparatus of claim 1 , wherein said support structure further comprises:a. a vacuum chamber comprising an inner support surface able to hold said skin-related tissue structure in a desired shape and position to enable said implanting tool to implant said dermal micro-organ into said skin-related tissue structure, wherein said third tubular element is connected to said vacuum chamber; andb. one or more vacuum channels to fluidically connect said vacuum chamber with at least one vacuum source.3. The apparatus of claim 2 , wherein said vacuum chamber further comprisesa. at least an elevated protrusion, said elevated protrusion able to support a plateau of epidermal and dermal skin layers from said skin-related tissue structure above the trajectory of said implanting tool; andb. a central channel co-axial with said third tubular element and distal to said elevated protrusion relative to said site of insertion, said central channel able to support skin-related tissue.5. The apparatus of claim 4 , wherein said fourth tubular element is an inner needle and said fifth tubular element is an outer sleeve.6. The ...

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02-05-2013 дата публикации

Refractive-diffractive ophthalmic device and compositions useful for producing same

Номер: US20130107201A1

A multifocal ophthalmic device is disclosed, wherein the lens body comprises a curcuminoid compound as a UV-light stabilizer, and/or a co-polymeric composition which is derived from a pre-polymerization mixture of defined monomers The lens body of the multifocal ophthalmic device is being formed with a plurality of concentric annular zones, which effect both diffraction and refraction of incident light, and which are separated by slanted steps that are substantially devoid of any diffractive or refractive power.

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02-05-2013 дата публикации

POLYMERIC COMPOSITION FOR OCULAR DEVICES

Номер: US20130109779A1

Polymeric and co-polymeric compositions useful for preparing ophthalmic and ocular devices, such as implantable intraocular lenses (IOL) and contact lenses, and processes of forming the compositions and devices are provided. The disclosed polymeric or co-polymeric composition may include a curcuminoid compound as a UV-blocker, and is derived from a pre-polymerization mixture of monomers which comprises at least 50 weight percents acrylate monomers and exhibiting visible light transparency and ultraviolet light opacity. The disclosed co-polymeric composition may alternatively, or in addition, be derived from a pre-polymerization mixture of defined monomers. 146-. (canceled)47. A co-polymeric composition comprising a polymeric backbone composed of a plurality of backbone units covalently linked to one another , said backbone units being derived from a pre-polymerization mixture of monomers which comprises:a first aromatic acrylate monomer, characterized as forming a first homopolymer having a refractive index that ranges from 1.50 to 1.53;a second aromatic acrylate monomer, characterized as forming a second homopolymer having a Tg lower by a range of 2° C. to 30° C. than a Tg of said first homopolymer;a third monomer, characterized as forming a third homopolymer having a Tg lower than 35° C.;a fourth monomer, characterized as forming a fourth homopolymer which is capable of absorbing water to at least 20% of the total weight of said fourth homopolymer; anda fifth monomer, being a crosslinking monomer,wherein:a concentration of said first aromatic acrylate monomer ranges from 50% to 60% of the total weight of the composition;a concentration of said second aromatic acrylate monomer ranges from 15% to 20% of the total weight of the composition;a concentration of said third monomer ranges from 10% to 15% of the total weight of the composition;a concentration of said fourth monomer ranges from 5% to 10% of the total weight of the composition;a concentration of said fifth ...

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02-05-2013 дата публикации

INTRAOCULAR LENS

Номер: US20130110233A1
Автор: Ghabra Marwan
Принадлежит:

A vision correction arrangement is described in which a lens system having variable optical power varies in dependence on the orientation of the user's eye. The vision correction arrangement may be embodied as an intraocular lens implant, or an extraocular device such as spectacles. The intraocular lens implant comprises a fixed lens element () and a movable lens () element sensitive to the orientation of the eye, so that the optical power of the intraocular lens implant is increased when the user looks downward, and returns to a reduced optical power condition when the user's eye returns to a horizontal gaze. The fixed lens element may have a convex rear surface and a concave front surface, and the second lens element may be pivotally mounted in front of the first lens element, so that downward inclination of the eye causes the second lens element to swing away from the fixed lens element. 1. An intraocular lens implant comprising:an optical combination of a first lens element and a second lens element;securing means to fix the first lens element relative to a lens capsule with a front surface directed towards the iris of the eye; andmounting means to mount the second lens element for pivoting movement under gravity between a first position in which the second lens is adjacent the front surface of the first lens and the optical combination has a first optical power, and a second position in which the second lens is spaced from the first lens and the optical combination has a second optical power greater than the first optical power;wherein the second lens element has an asymmetric “teardrop” or “pear” shape with a thinner region at its upper part, and the arrangement being such that directing the front surface of the first lens element downwardly causes the second lens element to move to the second position, and directing the front surface of the first lens element horizontally or upwardly causes the second lens element to move to the first position.2. An ...

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02-05-2013 дата публикации

ACCOMMODATING INTRAOCULAR LENS WITH DEFORMABLE MATERIAL

Номер: US20130110235A1

An accommodating intraocular lens. The lens includes a substantially-rigid anterior member having an extrusion aperture. First transparent deformable material is disposed anterior to the posterior side of the anterior member. Second transparent deformable material is disposed adjacent the posterior surface of the first material, the second material having a different degree of deformability than the first material and having an index of refraction different from the index of refraction of the first material. This forms a refractive deformable interface between the body of first material and the body of the second material. Force applied to the second material causes that material to be extruded through the aperture so as to form a curved, refractive interface with the body of first material. A method for installation of the accommodating intraocular lens is also provided. 1. An accommodating intraocular lens , comprising:a substantially-rigid anterior member having an anterior side and a posterior side and an extrusion aperture there through;a body of a first transparent deformable material disposed anterior to the posterior side of the anterior member at least partially within the periphery of the extrusion aperture;a body of a second transparent deformable material having an anterior surface disposed at least partially adjacent the posterior surface of the body of first transparent material, the second transparent deformable material having a different degree of deformability than the first transparent deformable material and having an index of refraction different from the index of refraction of the first transparent deformable material, thereby forming a refractive deformable interface between the body of first transparent deformable material and the body of second transparent deformable material; anda posterior member having an anterior side and a posterior side, the anterior side being disposed against the posterior of the body of second transparent deformable ...

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09-05-2013 дата публикации

DISCRETE PRE-ASSEMBLED MONOLITHIC AIOL ASSEMBLAGES AND AIOL ASSEMBLIES INCLUDING SAME

Номер: US20130116781A1
Автор: Ben Nun Joshua
Принадлежит:

Accommodating intraocular lens (AIOL) assemblies including a discrete pre-assembled monolithic AIOL assemblage and a discrete haptics system having a haptics ring and at least two elongated C-shaped haptics for self-anchoring in a human scleral wall at the ciliary sulcus. The AIOL assemblages include an AIOL capsule and an integrally formed base member. The AIOL assemblages also include an annular haptics support surround posterior to an anterior structure on implantation in a human eye of a supine human. AIOL assemblies are assembled in situ by mounting a haptics system onto a previously implanted AIOL assemblage. The haptics system bears against the annular haptics support surround. The anterior structure is freely telescopically received in the haptics ring. 1. A discrete pre-assembled monolithic AIOL assemblage for implantation in a human eye of a supine human , the human eye having a human visual axis , a sclera wall of tough connective tissue , an annular ciliary sulcus , and a sphincter-like ciliary body for tensioning a capsular diaphragm in an anterior direction along the human visual axis on its relaxation from a contracted ciliary body state to a relaxed ciliary body state ,the AIOL assemblage for use with a discrete haptics system having a longitudinal haptics axis for co-axial alignment with the human visual axis and a haptics ring with at least two elongated generally C-shaped haptics extending therefrom in opposite directions in a plane perpendicular to said longitudinal haptics axis,each haptics terminating in an attachment plate having at least one pointed puncturing member for penetrating the tough connective tissue of the scleral wall for self-anchoring implantation at at least two spaced apart stationary anchor points in the sclera wall at the annular ciliary sulcus,said haptics ring having a leading haptics ring end face, an internal peripheral haptics ring surface and a trailing haptics ring end face opposite said leading haptics ring end face, ...

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09-05-2013 дата публикации

APPARATUS AND METHODS FOR NIPPLE FORMATION VIA COLLAPSIBLE DEVICES

Номер: US20130116782A1

Apparatus and methods for nipple and breast formation are described where devices precondition or expand a target nipple tissue to reduce the pressure exerted by the skin on an eventual implant. Generally, the apparatus comprises a mold having a contact surface which is curved in conformance with a breast upon which the mold is positionable, the contact surface having an adhesive for securement upon the breast, and the mold defining a cavity along the contact surface which conforms to a size of a nipple to be formed upon the breast and where the cavity further comprises the adhesive for securement to the nipple. A breast enlargement device comprises a cup larger than the target breast and further defines an inner surface which adheres to the breast when contacted. 1. A nipple forming apparatus , comprising:a mold having, a contact surface which is curvable in conformance with a breast upon which the mold is positionable, wherein the contact surface comprises an adhesive for securement upon the breast, the mold having a first collapsed configuration for adhering to a region of the breast and a second molding configuration which defines a receiving cavity for drawing the adhered region of the breast away from as remainder of the breast; anda mold skirt which is attached to a portion of the mold and is reconfigurable between a first extended configuration where the mold in its first collapsed configuration is positionable against the region of the breast and a second supporting configuration where the mold skirt forms a smoothed surface relative to the mold in its second molding configuration.2. The apparatus of wherein the mold is invertible.3. The apparatus of wherein the mold is hollow.4. The apparatus of wherein the mold is made from an elastomeric material having a first durometer of Shore A 30-70 more specifically Shore A 50 claim 1 , and the cavity that has a second hardness which is higher than the first stiffness of Shore 40-80 claim 1 , more specifically ...

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09-05-2013 дата публикации

Silk based implantable medical devices and methods for determining suitability for use in humans

Номер: US20130116785A1
Принадлежит: Allergan Inc

Methods for determining suitability of an implantable silk scaffold for use in human soft tissue repair by implanting a silk scaffold in a quadruped. The silk scaffold is completely or essentially completely bioresorbed by twelve months after implantation, the silk scaffold (to the extent remaining) with ingrown tissue shows at least about a 60% strength increase by 12 months after implantation, and the thickness of the silk scaffold (to the extent remaining) with ingrown tissue increases by more than 100% by 12 months after implantation.

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09-05-2013 дата публикации

BREAST PROSTHESIS FILLED WITH MICROSPHERES OF THERMOEXPANDED POLYMER

Номер: US20130116786A1
Принадлежит:

A breast prosthesis constructed from a bag of elastic material or biocompatible mesh having a front face forming a dome and a rear face forming a base with a sealed and seamless interior cavity filled with microspheres of foam polymers or thereto expanded polymers or a combination of both. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. A breast prosthesis constructed from a bag having a sealed and seamless interior cavity , where the bag has a front face that forms a dome and a rear face that forms a base , and where the interior cavity contains a plurality of microspheres.6. A breast prosthesis according to where the microspheres are made from foam polymers.7. A breast prosthesis according to where the microspheres are made from thermo expanded polymers.8. A breast prosthesis according to where the microspheres are made from a combination of foam and thermo expanded polymers.9. A breast prosthesis according to where the bag is made of elastic material.10. A breast prosthesis according to where the elastic material is silicone elastomer.11. A breast prosthesis according to where the bag is made of elastic material.12. A breast prosthesis according to where the elastic material is silicone elastomer.13. A breast prosthesis according to where the bag is made of elastic material.14. A breast prosthesis according to where the elastic material is silicone elastomer.15. A breast prosthesis according to where the bag is a mesh of biocompatible material.16. A breast prosthesis according to where the bag is a mesh of biocompatible material.17. A breast prosthesis according to where the bag is a mesh of biocompatible material. This invention is generally related to the breast implant with thermo-expanded polymer microspheres filler. Concretely, the invention consists of a breast implant comprising an implant pocket or shell with an interior cavity, based on elastic material, and which has a front part, that constitutes a dome, a back part that constitutes a base, a ...

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16-05-2013 дата публикации

Corneal Implant Storage and Delivery Devices

Номер: US20130123916A1
Принадлежит:

Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants. 1. A corneal implant applicator apparatus , comprising:a corneal applicator member comprising an applicator;a corneal implant support disposed relative to the applicator to form an implant chamber; andwherein the applicator and the corneal implant support are adapted such that a corneal implant has a greater preference for adhering to the applicator than to the corneal implant support.2. The apparatus of wherein the applicator is adapted such that the corneal implant has a greater preference for adhering to corneal tissue than to the applicator.3. The apparatus of wherein the applicator has a radius of curvature that is greater than a radius of curvature of an anterior surface of the corneal implant.4. The apparatus of wherein the corneal implant support has a surface with a contour different than a contour of a surface of the applicator claim 1 , and wherein the different contours provide the corneal implant with the greater preference for adhering to the applicator than to the corneal implant support.5. The apparatus of wherein the applicator surface is smoother than the surface of the corneal implant support.6. The apparatus of wherein the corneal implant support is adapted to be moved relative to the applicator to provide access to the corneal implant and allow the corneal implant to preferentially adhere to the applicator.7. The apparatus of wherein the corneal implant support is detachably secured to the applicator.8. The apparatus of further comprising at least one clip adapted to detachably secure the corneal implant support to the applicator.9. The apparatus of further comprising a fluid disposed within the implant chamber.10. The apparatus of wherein the corneal implant is made from a hydrophilic material.11. The apparatus of wherein the corneal implant is made from a hydrogel material.12. The apparatus of ...

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16-05-2013 дата публикации

Human implantable tissue expander

Номер: US20130123918A1
Автор: Ami Glicksman
Принадлежит: Implite Ltd

A human implantable tissue expander including a biocompatible implantable structural skeleton element having a predetermined overall three-dimensional shape and defining at least one wall portion having formed therein apertures extending from an interior thereof to an exterior thereof and being operative, when implanted in human tissue, to permit fluid flow through the apertures and to generally maintain the predetermined three-dimensional shape generally independently of its orientation relative to gravitational acceleration.

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16-05-2013 дата публикации

METHODS AND DEVICES FOR RADIO FREQUENCY (RF) MITIGATION PROXIMATE THE EAR

Номер: US20130123919A1
Принадлежит: Personics Holdings Inc.

Earpieces and methods of forming earpieces for radio frequency (RF) mitigation are provided. An earpiece is configured to be inserted in an ear canal. The earpiece includes an insertion element and a sealing section disposed on the insertion element and configured to conform to the ear canal. The sealing section is configured to substantially mitigate radio frequency (RF) transmission and to substantially isolate the ear canal from an ambient environment. 1. An earpiece configured to be inserted in an ear canal comprising:an insertion element; anda sealing section disposed on the insertion element and configured to conform to the ear canal,wherein the sealing section is configured to substantially mitigate radio frequency (RF) transmission and to substantially isolate the ear canal from an ambient environment.2. The earpiece according to claim 1 , wherein the sealing section includes a plurality of particles configured to at least one of interfere with the RF transmission claim 1 , absorb the RF transmission or reflect the RF transmission.3. The earpiece according to claim 2 , wherein the particles include at least one of ferromagnetic particles claim 2 , ferrimagnetic particles or electrically conductive particles.4. The earpiece according to claim 1 , wherein the sealing section includes:a mixture of a medium and a plurality of particles, the particles configured to substantially mitigate the RF transmission; andan expandable element disposed on the insertion element, the expandable element configured to receive the mixture and to expand, responsive to the mixture, to conform to the ear canal.5. The earpiece according to claim 4 , wherein the expandable element is formed from a material including at least one of silicone claim 4 , rubber claim 4 , a polyurethane elastomer or an RF absorbing elastomer.6. The earpiece according to claim 4 , wherein the medium includes at least one of a liquid or a gel.7. The earpiece according to claim 6 , wherein the liquid ...

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23-05-2013 дата публикации

BREAST RECONSTRUCTION OR AUGMENTATION USING COMPUTER-MODELED DEPOSITION OF PROCESSED ADIPOSE TISSUE

Номер: US20130131655A1
Автор: Baroni Guido, Rigotti Gino
Принадлежит: ALLERGAN, INC.

A tissue transfer method for reconstruction and augmentation of soft tissue. The method includes harvesting adipose tissue from a patient. The harvested tissue is processed via centrifugation to isolate a purified subset of the adipose tissue including separating and removing a substantial amount of triglycerides from the harvested adipose tissue. The centrifugation may be performed to cause separation of water from the purified adipose tissue and to cause separation of oil from mature adipocytes. Specifically, the spin rates may be selected to be high enough to cause lesions in the mature adipocytes that results in the release of the oil. The method continues with implanting the purified adipose tissue into the patient at a breast or other area identified for reconstruction or augmentation. The implanting is performed based on an injection pathway model that defines injection point locations and a number of injection pathway directions from each point. 1. A method of reconstructing a breast of a patient after radiation therapy , comprising:generating a model of a plurality of injection points and injection pathways at each of the injection points for the breast, wherein the model defines locations of each of the injection points and a direction for each of the injection pathways;purifying a volume of adipose tissue by removing a volume of triglycerides from the adipose tissue and a volume of oil from damaged, mature adipocytes in the adipose tissue; andtransferring the volume of the purified adipose tissue into the breast of the patient by implanting a portion of the volume of the purified adipose tissue based on the defined injection points and injection pathways of the generated model.2. The method of claim 1 , wherein the model generating comprises generating a 3D surface model of the breast based on a digital model of the patient's other breast and overlaying the injection points and injection pathways on the 3D surface model.3. The method of claim 1 , further ...

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23-05-2013 дата публикации

Accommodating Intraocular Lenses and Methods of Use

Номер: US20130131794A1
Принадлежит:

Accommodating intraocular lenses and methods of use. The accommodating intraocular lenses include peripheral regions that are adapted to be more sensitive to certain types of forces than to other types of forces. 1. An accommodating intraocular lens , comprising:an optic portion comprising an optic fluid chamber; anda peripheral non-optic portion secured to and extending peripherally from the optic portion, the peripheral non-optic portion comprising a peripheral fluid chamber in fluid communication with the optic fluid chamber,wherein the peripheral non-optic portion is adapted to deform in response to forces on the peripheral non-optic portion due to ciliary muscle movement to thereby move a fluid between the peripheral fluid chamber and the optic fluid chamber to change an optical parameter of the accommodating intraocular lens,wherein the peripheral non-optic portion is adapted to be more sensitive to forces in the radial direction than it is to forces in the anterior-to-posterior direction.2. The accommodating intraocular lens of wherein the peripheral non-optic portion is adapted to deform in response to capsular bag forces on the peripheral non-optic portion due to ciliary muscle movement to thereby move a fluid between the peripheral fluid chamber and the optic fluid chamber to change an optical parameter of the accommodating intraocular lens.3. The accommodating intraocular lens of wherein the peripheral non-optic portion is adapted to be more sensitive to capsular bag forces in the radial direction than it is to capsular bag forces in the anterior-to-posterior direction.4. The accommodating intraocular lens of wherein the peripheral non-optic portion is adapted to deform more in response to forces in the radial direction that it is to forces in the anterior-to-posterior direction.5. The accommodating intraocular lens of wherein the peripheral non-optic portion is adapted such that a greater volume of fluid moves between the peripheral fluid chamber and the ...

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23-05-2013 дата публикации

SYSTEM AND METHOD FOR INCREASING THE DEPTH OF FOCUS OF THE HUMAN EYE

Номер: US20130131795A1
Принадлежит: BOSTON INNOVATIVE OPTICS, INC.

A method and apparatus for increasing the depth of focus of the human eye is comprised of a lens body, an optic in the lens body configured to produce light interference, and a pinhole-like optical aperture substantially in the center of the optic. The optic may be configured to produce light scattering or composed of a light reflective material. Alternatively, the optic may increase the depth of focus via a combination of light interference, light scattering, light reflection and/or light absorption. The optic may also be configured as a series of concentric circles, a weave, a pattern of particles, or a pattern of curvatures. One method involves screening a patient for an ophthalmic lens using a pinhole screening device in the lens to increase the patient's depth of focus. Another method comprises surgically implanting a mask in the patient's eye to increase the depth of focus. 1. An implantable ophthalmic mask comprising:a centrally located pinhole aperture configured to increase depth of focus; anda structure surrounding the aperture, the structure having varying degrees of opacity, each of the varying degrees of opacity preventing transmission of a substantial portion of visible light incident on the structure.2. The implantable ophthalmic mask of claim 1 , wherein the mask is configured to produce light interference.3. The implantable ophthalmic mask of claim 2 , wherein the structure is configured to minimize transmission of light by producing negative interference of light directed toward the structure.4. The implantable ophthalmic mask of claim 3 , wherein the mask is configured to transmit light by producing positive interference of light directed toward the mask.5. The implantable ophthalmic mask of claim 1 , wherein the mask is configured to produce light scattering.6. The implantable ophthalmic mask of claim 1 , wherein the mask is configured to block visual aberrations.7. The implantable ophthalmic mask of claim 1 , wherein the mask comprises embedded ...

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23-05-2013 дата публикации

INTRAOCULAR LENS (IOL) WITH MULTI OPTICS ASSEMBLY

Номер: US20130131796A1
Автор: Mirlay Ram Srikanth
Принадлежит:

The various embodiments of the present invention provide a multi-optics intraocular lens (IOL) scaffold assembly for incorporation into a capsular bag of an eye of a subject, provided with a ring platform and a protective umbrella. Several anterior and posterior ribs are hinged to the ring platform to support a posterior lens and an anterior lens. The dynamic spring elastic junctions are provided between the anterior and posterior ribs. The pendulum IOL assembly of the multi-optics intraocular lens (IOL) scaffold assembly enables a near vision of the objects using an optical system designed for a distance focusing in normal gaze. The pendulum IOL assembly has a posterior lens fixed to an equatorial ring platform and a secondary hanging lens provided with a weight at the lower end to act like a pendulum which swings with the posture of the eye. 1. A multi-optics intraocular lens (IOL) scaffold assembly for incorporation into a capsular bag of an eye of a subject , comprising:an anterior ring with an anterior optical lens, disposed in the anterior region of the capsular bag;a posterior optical lens disposed in the posterior region of the capsular bag;a plurality of movable anterior and posterior ribs disposed to extend radially from the anterior ring and the posterior optical lens, and anchored to a ring platform, through a plurality of hinges;a hinge protective umbrella disposed to enclose the ring platform; anda plurality of dynamic elastic spring junctions operably connected to the anterior and posterior ribs.2. The IOL scaffold assembly according to claim 1 , wherein the anterior ribs and posterior ribs are anchored to the ring platform and disposed to move the anterior and posterior ribs farther from and closed to each other.3. The IOL scaffold assembly according to claim 1 , wherein the anterior and posterior ribs are convex with intervening spaces.4. The IOL scaffold assembly according to claim 1 , wherein the anterior and posterior ribs are covered with webs ...

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23-05-2013 дата публикации

RETINAL IMPLANT AND VISUAL PROSTHESIS INCORPORATING SUCH AN IMPLANT

Номер: US20130131797A1
Принадлежит: IMI INTELLIGENT MEDICAL IMPLANTS AG

A system for generating artificial vision in a subject, comprising: an image capture means for capturing an image from a surrounding environment; an image processing means for processing the image and converting the image into an image signal; and a retinal implant or stimulation device () configured to be implanted within an eye of a patient and positioned on or adjacent the retina. The implant or stimulation device () comprises a substrate () and a plurality of light sources () arranged in an array on the substrate () for stimulating nerve cells of the retina, wherein each of the plurality of light sources () is configured to emit infrared radiation to stimulate one or more nerve cells in response to a respective stimulation signal derived from the image signal. 1. A retinal prosthesis comprising:a substrate, anda plurality of light sources arranged in an array on the substrate,wherein the prosthesis is configured to be implanted within an eye of a subject and positioned on or adjacent the retina, and wherein each of the light sources is configured to emit infrared radiation to stimulate nerve cells of the retina.2. The retinal prosthesis of claim 1 , wherein each of the light sources is configured to emit infrared radiation having a wavelength in the range of about 0.75 μm to 3.0 μm claim 1 , and preferably in the range of 1.5 μm to 2.5 μm; and/orwherein the plurality of light sources are configured to be controlled for independent actuation based on stimulation signals transmitted to or generated by the prosthesis.3. The retinal prosthesis of claim 2 , wherein the prosthesis is configured to receive telemetrically transmitted stimulation signals.4. The retinal prosthesis of claim 1 , wherein each of the plurality of light sources comprises a laser diode claim 1 , preferably a vertical-cavity surface-emitting laser (VCSEL) diode claim 1 , and wherein the laser diodes are arranged in an array on a semiconductor material claim 1 , such as an integrated circuit or ...

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23-05-2013 дата публикации

Moldable Back Breast Form

Номер: US20130131798A1
Принадлежит: AMERICAN BREAST CARE, LP

A breast prosthesis for wearing against a chest of a user includes a bag, a first silicone rubber and a silicone agglomerate putty. The bag includes at least three films that are sealed together around a periphery so as to define at least a front chamber and a back chamber. The first silicone rubber is disposed in the front chamber and is cured in an outer shape of a breast. The silicone agglomerate putty is disposed in the back chamber and is configured as a shear thinning fluid that conforms in shape to surface features of the chest of the user when placed against the chest of the user. 1. A breast prosthesis for wearing against a chest of a user , comprising:(a) a bag that includes at least three films that are sealed together around a periphery so as to define at least a front chamber and a back chamber;(b) a first silicone rubber disposed in the front chamber and cured in an outer shape of a breast; and(c) a silicone agglomerate putty that is disposed in the back chamber and that is configured as a shear thinning fluid that conforms in shape to surface features of the chest of the user when placed against the chest of the user.2. The breast prosthesis of claim 1 , wherein the bag further comprises a fourth film so that the bag defines a middle chamber claim 1 , a second silicone rubber claim 1 , different from the first silicone rubber claim 1 , disposed in the middle chamber.3. The breast prosthesis of claim 2 , wherein the first silicone rubber comprises a lightweight silicone rubber and wherein the second silicone rubber comprises a firm silicone that is configured to provide support to the breast prosthesis.4. The breast prosthesis of claim 1 , wherein the silicone agglomerate putty comprises an agglomerate of finely ground silicone rubber particles swollen with a liquid.5. The breast prosthesis of claim 4 , wherein the liquid comprises a liquid selected from a list consisting of: a silicone oil claim 4 , a non-silicone oil claim 4 , an alcohol claim 4 , an ...

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23-05-2013 дата публикации

SELF-SEALING SHELL FOR INFLATABLE PROSTHESES

Номер: US20130131799A1
Автор: Schuessler David
Принадлежит: ALLERGAN, INC.

A self-sealing shell useful as a component of a soft fluid-filled prosthetic implant is provided. The shell is at least partly constructed of a wall made of a colloid of an elastomeric polymer matrix and particles of a water-swellable material distributed therein. 1. An implantable article of manufacture useful as a component of an inflatable prosthesis , the article made by the steps of:providing a curable polymer-based liquid;distributing a plurality of solid, water swellable particles in the liquid to form a fluid mixture comprising a liquid polymer and solid, water swellable particles;allowing the mixture to solidify to form a polymeric matrix having solid, water swellable particles occupying enclosed spaces in the matrix; andforming the mixture into a wall of an inflatable prosthesis;wherein, when the wall is contacted with an aqueous fluid, the water swellable particles expand and the wall becomes self-sealing to a needle puncture.2. The article of wherein the wall is not self sealing to a needle puncture when it is in a dry state.3. The article of wherein the particles comprise hydrogel particles.4. The article of wherein the particles comprise a hydrogel comprising polyethylene glycol.59-. (canceled)10. The article of wherein the water swellable particles make up between about 2% to about 40% by weight of the mixture.11. The article of wherein the water swellable particles make up about 25% by weight of the mixture.12. A method of making an implantable article useful as a component of an inflatable prosthesis claim 1 , the method comprising the steps of:providing a curable polymer-based liquid;distributing a plurality of solid, water swellable particles in the liquid to form a fluid mixture comprising a liquid polymer and solid, water soluble particles;allowing the mixture to solidify to form a polymeric matrix having solid, water swellable particles occupying enclosed spaces in the matrix; andforming the mixture into a wall of an inflatable prosthesis; ...

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23-05-2013 дата публикации

SELF-SEALING SHELL FOR INFLATABLE PROSTHESES

Номер: US20130131801A1
Автор: Schuessler David J.
Принадлежит: ALLERGAN, INC.

A self-sealing shell useful as a component of a soft fluid-filled prosthetic implant is provided. The shell is at least partly constructed of a wall made of a colloid of an elastomeric polymer matrix and particles of a water-soluble material distributed therein. 1. An implantable article of manufacture useful as a component of an inflatable prosthesis , the article made by the steps of:providing a curable polymer-based liquid;distributing a plurality of solid, water soluble particles in the liquid to form a fluid mixture comprising a liquid polymer and solid, water soluble particles;allowing the mixture to solidify to form a polymeric matrix having solid, water soluble particles occupying enclosed spaces in the matrix,forming the mixture into a wall of an inflatable prosthesis;wherein, when the wall is contacted with an aqueous fluid, the water soluble particles at least partially dissolve and cause expansion of the enclosed spaces and the wall becomes self-sealing to a needle puncture.2. The article of wherein the wall is not self sealing when it is in a dry state.3. The article of wherein the particles comprise salt particles.4. The article of wherein the water soluble particles make up between about 2% to about 20% by weight of the mixture.5. A method of making an implantable article useful as a component of an inflatable prosthesis claim 1 , the method comprising the steps of:providing a curable polymer-based liquid;distributing a plurality of solid, water soluble particles in the liquid to form a fluid mixture comprising a liquid polymer and solid, water soluble particles;allowing the mixture to solidify to form a polymeric matrix having solid, water soluble particles occupying enclosed spaces in the matrix,forming the mixture into a wall of an inflatable prosthesis;wherein, when the wall is contacted with an aqueous fluid, the water soluble particles at least partially dissolve and cause expansion of the enclosed spaces and the wall becomes self-sealing to a ...

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30-05-2013 дата публикации

Optical material and method for modifying the refractive index

Номер: US20130138093A1
Принадлежит: Bausch and Lomb Inc, UNIVERSITY OF ROCHESTER

An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.

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30-05-2013 дата публикации

Adjustable Chiral Ophthalmic Lens

Номер: US20130138208A1
Принадлежит: AKKOLENS INTERNATIONAL B.V.

The present invention relates to an adjustable ophthalmic lens comprising at least one optical element comprising a combination of at least two optical surfaces wherein both optical surfaces are chiral optical surfaces adapted to provide chiral modulation of the light beam, the combination of the chiral optical surfaces is adapted to provide at least one adjustable focus and the combination of the chiral optical surfaces is adapted such that the focal distance of the adjustable foci depends on the mutual position of the chiral optical surfaces. These chiral optical surfaces result in a chiral modulation of the light beam. Combinations of chiral optical surfaces are applied to obtain adjustable optical powers in single-focus ophthalmic lenses and multiple-focus ophthalmic lenses. 1. An adjustable ophthalmic lens comprising at least one optical element including a combination of at least two optical surfaces wherein:both optical surfaces are chiral optical surfaces adapted to provide chiral modulation of the light beam,the combination of the chiral optical surfaces is adapted to provide at least one adjustable focus,and that the combination of the chiral optical surfaces is adapted such that the focal distance of the adjustable foci depends on the mutual position of the chiral optical surfaces.2. The lens as claimed in claim 1 , wherein the lens comprises at least two optical elements of which at least two optical elements comprise at least one chiral optical surface.3. The lens as claimed in claim 1 , wherein the lens comprises one optical element which element comprises at least two chiral optical surfaces.4. The lens as claimed in claim 1 , wherein at least one of the optical elements comprises a surface component adapted to correct at least one aberration of the eye or at least one aberration of the lens itself.5. The lens according to claim 1 , wherein the mutual position is the mutual rotational position of the chiral optical elements around any axis parallel to ...

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13-06-2013 дата публикации

Muscle-based grafts/implants

Номер: US20130149356A1
Принадлежит: RTI Biologics Inc

The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.

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13-06-2013 дата публикации

Ocular Implant Architectures

Номер: US20130150959A1
Принадлежит: Individual

An ocular implant having a first spine; a second spine; a first strut extending in an axial direction Z between the first spine and the second spine; a second strut extending in an axial direction Z between the first spine and the second spine; wherein an angular dimension θ of a first edge of each strut undulates as the strut extends in the axial direction Z between the first spine and the second spine; and wherein a radius r of an outer surface of each strut remains substantially constant as the strut extends the axial direction Z between the first spine and the second spine.

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13-06-2013 дата публикации

ACCOMMODATING INTRAOCULAR LENS

Номер: US20130150960A1
Принадлежит:

Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. The lenses can be made from silicone, fluorosilicone, and phenyl substituted silicone and be semipermeable to air. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens. 1. An intraocular lens apparatus , comprising:a biocompatible polymer balloon Tillable with an optically clear medium, the balloon configured for insertion into a capsular bag of an eye; andan elastomeric patch intimately attached to the balloon, the elastomeric patch having a thickness sufficient self-sealing of needle punctures at nominal lens pressures.2. The apparatus of wherein the elastomeric patch has a thickness equal to or greater than 100 μm.3. The apparatus of wherein the elastomeric patch has a thickness equal to or less than 700 μm claim 2 , thereby being thin enough to avoid contact with a posterior iris when implanted in an eye.4. The apparatus of wherein the elastomeric patch has a thickness between 150 μm and 350 μm.5. The apparatus of wherein the elastomeric patch includes a preformed slit adapted for a needle to pass therethrough.6. The apparatus of wherein the pre-formed slit includes a stepped portion.7. The apparatus of wherein the elastomeric patch has a concave innermost edge claim 1 , the concave edge of the patch located outside an optical path of the lens apparatus.8. The apparatus of further including:a circumferential sharp edge on an anterior side of the balloon configured to prevent ...

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13-06-2013 дата публикации

METHOD OF IMPLANTING AN INTRAOCULAR LENS

Номер: US20130150961A1
Принадлежит: Visiogen, Inc.

A method is provided for implanting an accommodating intraocular lens system in a capsular bag of an eye. The method includes providing the accommodating intraocular lens having an anterior viewing element and a posterior viewing element. The anterior viewing element has a width in a range between approximately 4.5 millimeters and approximately 6.5 millimeters. The method further includes forming an opening in an anterior portion of the capsular bag. The opening has a minimum width not less than approximately 4 millimeters and has a maximum width not greater than approximately 6.0 millimeters. The method further includes placing the accommodating intraocular lens system within the capsular bag. The capsular bag overlaps at least a portion of the anterior viewing element and defines an overlap region with a width in a range between approximately 0.1 millimeters and approximately 0.75 millimeters. 1. A method of implanting an accommodating intraocular lens system in a capsular bag of an eye , the method comprising:providing an accommodating intraocular lens, the accommodating intraocular lens having a central region and a peripheral region, at least a portion of the central region being optically transmissive;forming an opening in an anterior region of the capsular bag; andplacing the accommodating intraocular lens within the capsular bag such that the capsular bag extends inwardly from the peripheral region of the intraocular lens towards the central region so that the capsular bag overlaps with at least a portion of the central region and defines an overlap region having a width AW, the width AW of the overlap region having a size such that the intraocular lens is properly positioned in the capsular bag.2. The method of claim 1 , wherein the width of the overlap region is constant over the overlap region.3. The method of claim 1 , wherein the width of the overlap region varies over the overlap region.4. The method of claim 1 , wherein the portion of the central ...

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13-06-2013 дата публикации

MAMMARY PROSTHESIS FILLED WITH EXPANDED POLYMER MICROSPHERES

Номер: US20130150962A1
Принадлежит:

A mammary prosthesis built from a sack of elastic material or biocompatible material having a sealed interior cavity with the sack having an anterior surface forming a dome and a posterior surface forming a base, with a sealed and seamless interior cavity filled with microspheres of foamed or expanded polymers or a combination of both. The sack may also be permeable to establish equilibrium between body fluids and interstitial volume of the microspheres. 1. A mammary prosthesis built from a sack having a sealed interior cavity , where the sack has an anterior surface fowling a dome and a posterior surface forming a base , and where the interior cavity fully contains a plurality of biocompatible microspheres with interstices between microspheres.2. A mammary prosthesis according to the where the microspheres are made from foamed polymers.3. A mammary prosthesis according to the where the microspheres are made from expanded polymers.4. A mammary prosthesis according to the where the microspheres are made from a combination of foamed and expanded polymers.5. A mammary prosthesis according to the where the microspheres are made from a nucleus material covered by a different cover material where both the nucleus material and cover material are biocompatible.6. A mammary prosthesis according to the where the microspheres have an expansion range between a specific gravity of 1.0 to 0.03.7. A mammary prosthesis according to the where the microspheres have an expansion range between a specific gravity of 1.0 to 0.03.8. A mammary prosthesis according to the where the microspheres have an expansion range between a specific gravity of 1.0 to 0.03.9. A mammary prosthesis according to the where the microspheres have a coefficient of friction as between microspheres ranging from 0.03 to 0.70.10. A mammary prosthesis according to the where the microspheres have a coefficient of friction as between microspheres ranging from 0.03 to 0.70.11. A mammary prosthesis according to the ...

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20-06-2013 дата публикации

INTRAVITREAL APPLICATION

Номер: US20130158561A1
Принадлежит: ALLERGAN, INC.

An assembly for implanting ocular implants into a mammalian eye is provided. The assembly generally includes a cannula having a curved distal end, an injector mechanism coupled to the cannula for linearly moving one or more implant segments in the cannula toward the curved distal end, and a rotator mechanism for rotating the cannula about a longitudinal axis thereof. 1. An assembly for implanting ocular implants into a mammalian eye , the assembly comprising:a cannula having a curved distal end;an injector mechanism coupled to the cannula for linearly moving one or more implant segments in the cannula toward the curved distal end; anda rotator mechanism for rotating the cannula about a longitudinal axis thereof.2. The assembly of wherein the injector mechanism comprises a drive rod assembly and a compression spring coupled thereto.3. The assembly of wherein the injector mechanism comprises a drive rod assembly claim 1 , a compression spring for driving forward the drive rod assembly claim 1 , and a plunger having a distal end movable in the cannula.4. The assembly of wherein the rotator mechanism is structured to rotate the curved distal end of the cannula in a stepwise manner.5. The assembly of wherein the rotator mechanism comprises a rotatable sleeve having helical ribs.6. The assembly of wherein the rotator mechanism comprises a rotatable sleeve having helical ribs and a torsion spring for applying a restoring force.7. The assembly of wherein the curved distal end of the cannula has a curvature radius of between about R 20 to about R 80.8. The assembly of wherein the curved distal end of the cannula has a curvature radius of between about R 40 to about R 60.9. The assembly of wherein the curved distal end of the cannula has a curvature radius of about R 50.10. The assembly of wherein the curved distal end of the cannula has a distal tip offset between about 0.1 mm to about 1.0 mm.11. The assembly of wherein the curved distal end of the cannula has a distal tip ...

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