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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 5230. Отображено 100.
12-01-2012 дата публикации

Aortic annuloplasty ring

Номер: US20120010701A1
Автор: Anthony Paolitto, Neil Bulman-Fleming, Raymond Cartier, Valerio Valentini
Принадлежит: Coroneo Inc

An annuloplasty ring to resize a dilated aortic root during valve sparing surgery includes a scalloped space frame having three trough sections connected to define three crest sections. The annuloplasty ring is mounted outside the aortic root, and extends in height between a base plane and a spaced apart commissure plane of the aortic root. At least two adjacent trough sections are coupled by an annulus-restraining member or tether that limits the maximum deflection of the base of the annuloplasty ring. In use, the tether is preferably located in proximity to the base plane of the aortic root. The annuloplasty ring is movable between a first, substantially conical configuration occurring during a diastolic phase of the cardiac cycle, and a second, substantially cylindrical configuration occurring during a systolic phase of the cardiac cycle.

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Номер записи: 1
26-01-2012 дата публикации

Multiple anchor delivery tool

Номер: US20120022557A1
Автор: Amir Gross, Ehud Iflah, Oz Cabiri, Tal Hammer, Tal Reich
Принадлежит: Valtech Cardio Ltd

An anchor deployment tool includes a flexible outer tube, within which is positioned a flexible inner shaft, and a rotating deployment element coupled to a distal end of the shaft. The tool is configured to provide an anchor storage area, which initially stores a plurality of tissue anchors, such that the inner shaft passes through channels of the anchors along entire longitudinal lengths of the anchors, and the anchors are within the outer tube. The rotating deployment element is configured to directly engage the anchors in the anchor storage area one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end and into tissue of a subject. Other embodiments are also described.

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Номер записи: 2
02-02-2012 дата публикации

Method of reshaping a ventricle

Номер: US20120029628A1
Автор: Stanton J. Rowe
Принадлежит: Edwards Lifesciences Corp

Methods for restoring the conical shape of a dilated heart ventricle, or at least reshaping the ventricle to a more conical shape to counter the effects of dilation, thereby improving pumping efficiency. In an exemplary embodiment, a reshaping apparatus comprises an implantable body that can be delivered to a dilated left ventricle via the patient's vasculature in a minimally-invasive procedure. When deployed inside the left ventricle, the body is adapted to apply a longitudinal (downward) force against the inner surface of the left ventricle that causes the ventricle to distend or elongate downwardly relative to the base of the heart so as to at least partially restore the conical shape of the heart. In other embodiments, one or more tension members can be secured to heart tissue inside a heart chamber or on the outside of the heart and placed in tension to reshape the geometry of the heart.

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Номер записи: 3
09-02-2012 дата публикации

Truncated Cone Heart Valve Stent

Номер: US20120035713A1
Автор: Georg Lutter, Lucian Lozonschi
Принадлежит: Tendyne Medical Inc

A heart valve stent having a section with a heart valve implant and several proximally disposed tissue anchors, also comprising a plurality of anchoring threats, each with a proximate end fastened to the stent or valve and a distal end attached to tissue within a heart chamber to provide tension between the heart chamber tissue and the stent.

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Номер записи: 4
15-03-2012 дата публикации

Stentless Support Structure

Номер: US20120065728A1
Автор: Christopher M. Banick, Gary A. Thill, John Gainor, Robert Foster Wilson
Принадлежит: Heart Leaflet Tech Inc

A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.

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Номер записи: 5
29-03-2012 дата публикации

Devices and Methods for Heart Valve Treatment

Номер: US20120078358A1
Автор: Cyril J. Schweich, Jr., David Kusz, Jason E. Kalgreen, Richard Schroeder, Robert M. Vidlund, Todd J. Mortier
Принадлежит: Edwards Lifesciences LLC

Devices and methods for treating heart valves include members that assist the valve in closing during at least a portion of the cardiac cycle. Such devices include members configured to alter the shape of a valve annulus, reposition at least one papillary muscle, and/or plug an orifice of the valve so as to provide a coaptation surface for the valve leaflets.

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Номер записи: 6
31-05-2012 дата публикации

Intraoperative and post-operative adjustment of an annuloplasty ring

Номер: US20120136433A1
Автор: Alexander Marmureanu, Jason Tran, Jesus Flores, Le Le, Samuel Shaolian
Принадлежит: Micardia Corp

An intraoperative adjustment device is described. In some embodiments, the device includes an elongate body including a proximal end and a distal end, the distal end configured to penetrate an outer surface of an adjustable cardiac implant implanted in a patient's heart, and the proximal end and the distal end connected by at least one energy-transfer member. In some embodiments, the distal end includes at least one electrode coupled to the energy-transfer member and configured to deliver an activation energy to the adjustable cardiac implant. In some embodiments, the proximal end is configured to attach to an energy source that provides the activation energy. In some embodiments, the proximal end is configured to be located outside the patient's body while the distal end is coupled to the adjustable cardiac implant that is implanted in the patient's heart.

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Номер записи: 7
07-06-2012 дата публикации

Three-dimensional annuloplasty ring

Номер: US20120143322A1
Автор: Patrick M. McCarthy, Richard S. Rhee, Stefan G. Schreck
Принадлежит: Edwards Lifesciences Corp

An annuloplasty ring having a three-dimensional discontinuous form generally arranged about an axis with two free ends that are axially offset. The ring is particularly suited for repair of the tricuspid valve, and more closely conforms to the annulus shape. The ring is more flexible in bending about radially extending axes than about the central axis. The ring may have an inner structural support covered by a pliable sleeve and/or a fabric tube. The structural support may have a varying cross-section, such as a C-shaped cross-section in a mid-section between two free ends and a rectangular cross-section at the free ends.

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Номер записи: 8
02-08-2012 дата публикации

Adjustable annuloplasty ring with subcutaneous activation port

Номер: US20120197392A1
Автор: Brian C. Gray, Daniel C. Anderson, Jeffrey P. DuMontelle, Maurice Buchbinder, Ninh H. Dang, Paul A. Molloy, Ross Tsukashima, Samuel M. Shaolian
Принадлежит: Micardia Corp

Annuloplasty rings are employed to treat heart valve defects, such as regurgitation. Synching the heart tissue to the ring restores the valve opening to its approximate original size and operating efficiency. Adjustable annuloplasty rings allow for a proper degree of synching both during open heart surgery and over the patient's lifetime. A subcutaneous port may be coupled to an adjustable annuloplasty ring such that an external activation energy generator can be used to heat the adjustable annuloplasty ring and thereby adjust the size of the annuloplasty ring.

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Номер записи: 9
09-08-2012 дата публикации

Device and method for temporary or permanent suspension of an implantable scaffolding containing an orifice for placement of a prosthetic or bio-prosthetic valve

Номер: US20120203336A1
Автор: Lon Sutherland ANNEST
Принадлежит: Individual

In a surgical method for improving cardiac function, an implantable scaffold Or valve support device is inserted inside a patient's heart and attached to the heart in a region adjacent to a natural mitral or other heart valve. The scaffold or valve support device defines an orifice and, after the attaching of the scaffold or valve support device to the heart, or temporary support while native valve leaflets and/or subvalvular structures are captured, a prosthetic or bio-prosthetic valve seated in the orifice, and the native valve may be retracted into the scaffold/replacement assembly to create a gasket for sealing the complex.

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Номер записи: 10
16-08-2012 дата публикации

Adjustable annuloplasty ring and activation system

Номер: US20120209379A1
Автор: Jason Tran, Jesus Flores, Le Le, Samuel M. Shaolian
Принадлежит: Micardia Corp

An adjustable annuloplasty device is described. In some embodiments, the device includes a body member having a surface that conforms at least partially to a cardiac valve annulus. The body member comprises a shape-memory member that transforms from a first configuration to a second configuration in response to an applied energy. In some embodiments, the device further includes a first electrode assembly, coupled to the shape-memory member, that transfers energy to the shape-memory member, and a second electrode assembly, coupled to the shape-memory member, that transfers at least a portion of the energy away from the shape-memory member.

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Номер записи: 11
20-09-2012 дата публикации

Non-Axisymmetric Aortic Valve Devices

Номер: US20120239143A1
Автор: Al Beavan, J. Scott Rankin, William E. Cohn
Принадлежит: BioStable Science and Engr Inc

The present disclosure provides aortic valve prosthetic devices that are constructed in a non-axisymmetric shape, or are expandable to a non-axisymmetric shape for improved results in the repair of defective aortic valves. The devices can be surgically implanted, or they can be implanted percutaneously through an insertion catheter. The expandable devices can be self-expanding or expanded by an inflatable balloon to a non-axisymmetric cross-section geometry.

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Номер записи: 12
27-09-2012 дата публикации

Device And A Method For Augmenting Heart Function

Номер: US20120245678A1
Автор: Jan Otto Solem
Принадлежит: Synergio AG

A device, a kit and a method are presented for permanently augmenting the pump function of the left heart. The basis for the presented innovation is an augmentation of the physiologically up and down movement of the mitral valve during each heart cycle. By means of catheter technique, minimal surgery, or open heart surgery implants are inserted into the left ventricle, the mitral valve annulus, the left atrium and adjacent tissue in order to augment the natural up and down movement of the mitral valve and thereby increasing the left ventricular diastolic filling and the piston effect of the closed mitral valve when moving towards the apex of said heart in systole and/or away from said apex in diastole.

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Номер записи: 13
11-10-2012 дата публикации

Apparatus and methods to create and maintain an intra-atrial pressure relief opening

Номер: US20120259263A1
Автор: David Celermajer, Edward McNamara, Hiroatsu Sugimoto, Michael W. Sutherland
Принадлежит: DC Devices Inc

The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.

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Номер записи: 14
15-11-2012 дата публикации

Intra-atrial implants made of non-braided material

Номер: US20120290062A1
Автор: David Celermajer, Edward McNamara, Hiroatsu Sugimoto, Stephen Forcucci
Принадлежит: Individual

Several unique intra-cardiac pressure devices, placement catheters, methods of placement and methods of treating heart failure are presented. The intra-cardiac pressure devices presented allow sufficient flow from the left atrium to the right atrium to enable the relief of elevated left atrial pressure and resulting patient symptoms. The intra-cardiac pressure devices are made of a non-braided material.

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Номер записи: 15
22-11-2012 дата публикации

Positioning Cage

Номер: US20120296160A1
Автор: Jason Hill, Scott R. Smith
Принадлежит: Boston Scientific Scimed Inc

A positioning device and method of using are provided herein. The positioning device includes an expandable cage through which blood can flow. The expandable cage is insertable into a bodily organ, for example a heart, and expanded to temporarily secure the positioning device within the organ. Then, the cage can be used to steady the implantation of an annuloplasty device, for example. Alternatively, the expanded cage can be used to locate a desired area or feature of the body organ in which it is inserted by way of fluoroscopy.

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Номер записи: 16
22-11-2012 дата публикации

Corkscrew Annuloplasty Device

Номер: US20120296417A1
Автор: Jason Hill, Mark L. Jenson
Принадлежит: Boston Scientific Scimed Inc

An annuloplasty device having a plurality of corkscrew anchors is herein disclosed. In some embodiments, the annuloplasty device includes a core wire extending along the length of the device, and at least one corkscrew wire which is operably connected to the corkscrews to screw the corkscrews into heart tissue. In certain embodiments, one or more of the corkscrew wires includes a drive key and the corkscrew anchors are connected to a sleeve with a keyway that engages the drive key on the corkscrew wires. In addition, in some embodiments, the device includes a retractable sheath, which is disposed over the corkscrews to protect them during insertion of the device.

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Номер записи: 17
22-11-2012 дата публикации

Annuloplasty Ring with Piercing Wire and Segmented Wire Lumen

Номер: US20120296420A1
Автор: Kevin D. Edmunds
Принадлежит: Boston Scientific Scimed Inc

An annuloplasty device having an expandable member, a plurality of lobes, and a piercing wire is herein disclosed. In some embodiments, the lobes extend radially outwardly from the expandable member. The lobes each have a wire lumen disposed therethrough, and the piercing wire is extendable through the wire lumen of each lobe to secure the device to adjacent heart tissue. In some embodiments, the expandable member comprises an inflatable medical balloon. In addition, a method of implanting an annuloplasty device is disclosed.

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Номер записи: 18
03-01-2013 дата публикации

Heart valve repair devices and methods

Номер: US20130006352A1
Автор: Ira Yaron
Принадлежит: MITRALIX Ltd

Devices and methods for the repair of the functioning of heart valves are provided. A device may comprise a first section having a generally spiral shape and a second section connected to the first section. A method involves positioning the device such that chords associated with the heart valve are positioned within the path of the generally spiral shape of the first section and positioning the second section on an opposite side of the heart valve. The first section may be turned in a manner such that the chords move closer to the center of the first section. The first section draws the chords closer together, thereby pulling the valve leaflets closer together in order to facilitate their coaptation and proper closing.

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Номер записи: 19
31-01-2013 дата публикации

Annuloplasty rings and methods for heart valve repair

Номер: US20130030523A1
Автор: Ajit P. Yoganathan, Jorge H. Jimenez, Sai Muralidhar PADALA, Vinod H. Thourani
Принадлежит: EMORY UNIVERSITY, Georgia Tech Research Corp

An annuloplasty ring, configured for implantation in the annulus of a heart valve, comprising multiple segments each of which are geometrically shaped from a three dimensional perspective to conform to the anatomic shape of the valve annulus. In one embodiment, the annuloplasty ring is configured to facilitate a reduction of tension on heart valve tissue and eliminate a substantial portion of potential pressure or force that may be applied to the atrioventricular node by the annuloplasty ring when implanted. In another embodiment, at the annuloplasty ring is configured to include an assembly that facilitates selective adjustment of a segment's respective length and/or shape. The adjustment of the length of one of the ring segment's results in an adjustment of at least one angle between at least one set of other ring segments, thereby causing an adjustment to the geometric characteristics of the ring.

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Номер записи: 20
14-03-2013 дата публикации

ADJUSTABLE IMPLANT SYSTEM

Номер: US20130066420A1
Автор: Anderson Daniel C., Pool Scott L., Shaolian Samuel M., Tsukashima Ross
Принадлежит: ELLIPSE TECHNOLOGIES, INC.

Systems and methods treat a heart valve using a magnetically adjustable annuloplasty ring attached to or near a cardiac valve annulus. A changing magnetic field may be used to selectively increase or decrease a circumference of, or otherwise modify the shape of, the implanted annuloplasty ring. The adjustable annuloplasty ring includes a tubular body member, one or more adjustable members, and an internal magnet within the tubular body member. The tubular body member and the one or more adjustable members form a ring shape. The internal magnet is configured to rotate in response to a rotating external magnetic field. The internal magnet is coupled to the one or more adjustable members to change a dimension of the ring shape as the internal magnet rotates. A system for treating a heart valve may include an external adjustment device having one or more external magnets to generate the rotating external magnetic field. 149-. (canceled)50. A system for changing the dimension of a portion of a subject comprising: a tubular member;', 'an internal magnet disposed within the tubular member, the internal magnet configured to rotate in response to a rotating external magnetic field;', 'an adjustable member operatively coupled to the internal magnet, wherein the internal magnet is configured to rotate in response to the rotating external magnetic field and change a dimension of the adjustable implant as the internal magnet rotates; and, 'an adjustable implant configured for implantation within a patient comprisinga magnetic brake configured for implantation within a patient, wherein, in the absence of the rotating external magnetic field, the magnetic brake is configured to prevent the internal magnet from rotating, and wherein, in the presence of the rotating magnetic field, the magnetic brake is configured to allow the internal magnet to rotate.51. The system of claim 50 , wherein the adjustable implant is an adjustable annuloplasty ring.52. The system of claim 50 , wherein ...

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Номер записи: 21
18-04-2013 дата публикации

Apparatus and method for guide-wire based advancement of a rotation assembly

Номер: US20130096672A1
Автор: Eran Miller, Tal Reich, Tal Sheps
Принадлежит: Valtech Cardio Ltd

Apparatus is provided, comprising (1) a guide member, (2) a tissue-adjustment mechanism having (a) an upper surface and a lower surface, (b) at least one first opening at the upper surface, (c) at least one second opening at the lower surface, and (4) a channel extending between the first and second openings, the channel facilitating advancement of the tissue-adjustment mechanism along the guide member; and (3) at least one repair chord coupled at a first portion thereof to the tissue-adjustment mechanism and having at least a first end that is configured to be coupled to a portion of tissue of a patient, the repair chord being configured to adjust a distance between the portion of tissue and the tissue-adjustment mechanism, in response to adjustment of the repair chord by the tissue-adjustment mechanism. Other embodiments are also described.

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Номер записи: 22
25-04-2013 дата публикации

TRANSVALVULAR INTRAANNULAR BAND FOR AORTIC VALVE REPAIR

Номер: US20130103142A1
Автор: Afzal Thomas, Christian Jeffrey, Hulme Gary, Reo Michael L., Subramanian Valavanur A.
Принадлежит: CARDIOVASCULAR TECHNOLOGIES, LLC

Aortic regurgitation can be treating by implanting in the aortic annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the aortic valve leaflets. The band may be implanted via translumenal access or via thoracotomy. 1. A transvalvular intraannular band , comprising:an elongate and arcuate body having a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion, the central portion displaced transversely from a plane which includes the first end and the second end;wherein the first end and the second end are configured to be attached to the aortic valve annulus within the plane of the annulus and the central portion is configured to support the aortic valve leaflets at a point displaced toward the ventricle from the plane.2. The transvalvular band of claim 1 , wherein the central portion is narrower than both the first anchoring portion and the second anchoring portion.3. The transvalvular band of claim 1 , wherein the central portion comprises an offset support portion and a first arm portion and a second arm portion claim 1 , the offset support portion wider than the first arm portion and second arm portion.4. The transvalvular band of claim 1 , wherein the central portion has a substantially triangular cross-section.5. A method of treating aortic regurgitation claim 1 , the method comprising:implanting in the aortic annulus a transvalvular band comprising an elongate and arcuate body having a first end, a first anchoring portion located proximate the first end, a second end, and a central portion, the central portion displaced out of the plane containing the first end and the ...

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Номер записи: 23
09-05-2013 дата публикации

External aortic ring and spool mechanism therefor

Номер: US20130116776A1
Автор: Amir Gross, Eran Miller, Oz Cabiri, Tal Reich, Tal Sheps
Принадлежит: Valtech Cardio Ltd

A method for repairing an aortic valve of a heart of a patient is provided, the method comprising (1) placing around a portion of an aorta of the patient in a vicinity of the aortic valve, an adjustable implant structure comprising an adjusting mechanism coupled to a first portion of a flexible contraction member; and (2) adjusting a dimension of the aortic valve by adjusting a dimension of the implant structure by rotating a rotatable structure of the adjusting mechanism. Other embodiments are also described.

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Номер записи: 24
09-05-2013 дата публикации

IMPLANT HAVING MULTIPLE ROTATIONAL ASSEMBLIES

Номер: US20130116780A1
Автор: CABIRI Oz, Gross Amir, Miller Eran, REICH Tal, Sheps Tal
Принадлежит: VALTECH CARDIO, LTD.

Apparatus is provided, comprising (1) an annuloplasty structure, shaped to define a perimeter, and configured to be disposed at the annulus of the native valve of the patient; (2) a first adjusting mechanism, coupled to the annuloplasty structure, and configured to adjust the perimeter; (3) at least one longitudinal flexible member, having a first end portion, and a second end portion that is configured to be coupled to tissue of the ventricle of the heart of the patient; and (4) at least a second adjusting mechanism, coupled to the annuloplasty structure such that the second adjusting mechanism is slidable around at least part of the perimeter, coupled to the first end portion of the longitudinal flexible member, and configured to adjust a distance between the second adjusting mechanism and the second end portion of the longitudinal flexible member. Other embodiments are also described. 1. Apparatus for use with a native valve of a heart of a patient , the native valve having a valve annulus , and the heart having a ventricle , the apparatus comprising:an annuloplasty structure, shaped to define a perimeter, and configured to be disposed at the annulus of the native valve of the patient;a first adjusting mechanism, coupled to the annuloplasty structure, and configured to adjust the perimeter of the annuloplasty structure;at least one longitudinal flexible member, having a first end portion, and a second end portion that is configured to be coupled to tissue of the ventricle of the heart of the patient; and coupled to the annuloplasty structure such that the second adjusting mechanism is slidable around at least part of the perimeter of the annuloplasty structure,', 'coupled to the first end portion of the at least one longitudinal flexible member, and', 'configured to adjust a distance between the second adjusting mechanism and the second end portion of the at least one longitudinal flexible member., 'at least a second adjusting mechanism24.-. (canceled)5. The ...

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Номер записи: 25
16-05-2013 дата публикации

INFLATABLE MINIMALLY INVASIVE SYSTEM FOR DELIVERING AND SECURING AN ANNULAR IMPLANT

Номер: US20130123910A1
Автор: Badia James, Baez Luis, Bentley Peter, Cartledge John P., Cartledge Richard G., McCrea James
Принадлежит: St. Jude Medical, Cardiology Division, Inc.

A delivery device for an annular implant that includes a balloon expansion mechanism and an annular implant having an adjustable dimension. The balloon expansion mechanism includes an inflation tube attached to a non-occluding balloon collar which is supported by trusses radially extending from a trocar. The annular implant further includes a flexible ring core, contiguous coiled spacers, and anchoring blocks. The flexible ring core is adjusted via a cinching mechanism. The anchoring blocks are spaced along the ring core by the contiguous coiled spacers, which keeps the distance between each pair of anchoring blocks equidistant as the ring core diameter is manipulated by the device user. The annular implant can also include gunbarrel elements housed in the trocar. Each gunbarrel element contains a gunbarrel pusher which drives an attachment element into the annular implant and annular tissue. 1. A delivery device for an annular implant comprising:a balloon expansion mechanism, wherein the balloon expansion mechanism comprises a hollow catheter attached to an inflation tube whereby a gas or liquid is fed through said inflation tube and a non-occluding balloon collar attached to the inflation tube to provide for expansion of the balloon collar, wherein the balloon collar is supported by a plurality of trusses radially extending from a trocar;an annular implant having an adjustable dimension removably mounted around the non-occluding balloon collar, wherein the annular implant is adjustable through at least one cinching cord; anda cinching mechanism attached to the annular implant, wherein the cinching mechanism reshapes the annular implant to conform to the size and shape of the annulus via the at least one cinching cord.2. The delivery device of claim 1 , wherein the annular implant includes a flexible ring core and wherein the flexible ring core is adjustable through two cinching cords.3. The delivery device of claim 1 , wherein the cinching mechanism comprises:a ...

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Номер записи: 26
16-05-2013 дата публикации

Catheter-Based Annuloplasty System and Method

Номер: US20130123913A1
Автор: Kuehn Stephen
Принадлежит: Medtronic, Inc.

A catheter-based annuloplasty system for use in repairing a heart valve having leaflets and a valve annulus, includes a delivery catheter having a proximal end and a distal end, and an expandable stent disposed on the distal end of the catheter. An adjustable annuloplasty ring is disposed on the expandable stent and is configured to expand and contract in response to expansion and contraction of the stent. 1. A catheter-based annuloplasty system for use in repairing a heart valve having leaflets and a valve annulus , comprising:a delivery catheter having a proximal end and a distal end;an expandable stent disposed on the distal end of the catheter; andan adjustable annuloplasty ring disposed on the expandable stent configured to expand and contract in response to expansion and contraction of the stent, wherein the adjustable ring includes at least one tissue attachment member configured to be attached to the valve annulus via movement of the expandable stent.2. The annuloplasty system of claim 1 , wherein the adjustable ring includes a plurality of tissue attachment members shaped for penetration into the valve annulus and configured to be triggered from a spring-loaded tensioned state to a relaxed state.3. The annuloplasty system of claim 2 , wherein each tissue attachment member comprises:a first prong portion extending from a first circular spring portion;a second prong portion extending from a second circular spring portion; anda cross-member connecting the first and second circular spring portions.4. The annuloplasty system of claim 3 , wherein the adjustable ring extends through the first and second circular spring portions of each of the tissue attachment members.5. The annuloplasty system of claim 3 , wherein the cross-member includes a feature configured to be connected to hold the adjustable ring adjacent to the expandable stent.6. The annuloplasty system of claim 2 , and further comprising:a plurality of tissue attachment retaining members disposed on the ...

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Номер записи: 27
23-05-2013 дата публикации

Catheter-based annuloplasty using ventricularly positioned catheter

Номер: US20130131791A1
Автор: Edwin J. Hlavka, Jonathan L. Podmore, Paul A. Spence
Принадлежит: Mitralign Inc

The present invention relates to a minimally invasive method of performing annuloplasty. According to one aspect of the present invention, a method for performing annuloplasty includes accessing a left ventricle of a heart to provide a discrete plication element to the left ventricle, and engaging the plication element to tissue near a mitral valve of the heart. Engaging the plication element includes causing the plication element to gather a portion of the tissue to create a plication. In one embodiment, accessing the left ventricle of the heart to provide the plication element includes accessing the left ventricle of the heart using a catheter arrangement.

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Номер записи: 28
23-05-2013 дата публикации

ACTIVELY-ENGAGEABLE MOVEMENT-RESTRICTION MECHANISM FOR USE WITH AN ANNULOPLASTY STRUCTURE

Номер: US20130131792A1
Автор: Baum Aviram, BEINART Iftah, CABIRI Oz, Gross Amir, Miller Eran
Принадлежит:

A method is provided, including providing an implant shaped to define a lumen and a flexible strip disposed at least in part within the lumen, and a plurality of recesses, the implant including a locking mechanism to which first and second ends of the strip are coupled such that the strip defines a closed loop which shortens when the first end is advanced through the locking mechanism in a first direction, and expands when the first end is advanced in a second opposite direction; advancing the first end in first and second opposing directions with respect to the second end; maintaining a recess-engaging portion in a position in which the recess-engaging portion is not disposed in any of the recesses during the advancing; and restricting the advancing by facilitating active positioning of the recess-engaging portion in one of the recesses. Other embodiments are also described. 1. A method , comprising: [ a first end,', 'a second end, and', 'a plurality of recesses, and, 'shaped so as to define a lumen therethrough and a flexible strip disposed at least in part within the lumen of the implant, the strip having, 'including a locking mechanism to which the first and second ends of the strip are coupled such that the strip defines a closed loop and a perimeter thereof which (a) shortens when the first end is advanced through the locking mechanism in a first direction and (b) expands when the first end is, 'providing an implantadvanced in a second direction opposite the first direction;advancing the first end of the strip in first and second opposing directions with respect to the second end of the strip;maintaining a recess-engaging portion in a position in which the recess-engaging portion is not disposed in any of the plurality of recesses during the advancing; andrestricting the advancing by facilitating active positioning of the recess-engaging portion in one of the plurality of recesses.2. The method according to claim 1 , further comprising coupling the implant ...

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Номер записи: 29
27-06-2013 дата публикации

ANCHORING DEVICE AND METHOD FOR REPLACING OR REPAIRING A HEART VALVE

Номер: US20130166022A1
Автор: Conklin Brian S.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

A device for anchoring a prosthetic heart valve or annuloplasty ring to a valve annulus in a heart and a method of implanting same is disclosed. The device can include a prosthetic valve or annuloplasty ring with one or more anchors configured to be threaded or otherwise passed underneath a native leaflet and/or subvalvular tissue to secure the device at the native annulus. 1. An anchoring device for a device intended for implantation at a native heart valve annulus , said anchoring device comprising:a central portion with one or more anchors extending therefrom, each of said one or more anchors having a proximal fixed end secured to the central portion and terminating in free end, said one or more anchors being spaced slightly away from and running substantially parallel to the circumference of the central portion in a curved fashion, forming valve leaflet-receiving slots between the anchors and the central portion.2. The anchoring device of claim 1 , wherein the anchors include a cross-section configured to have a different stiffness in-plane than the stiffness out-of-plane.3. The anchoring device of claim 1 , wherein the anchors are generally equidistantly positioned around the circumference central portion of the anchoring device.4. The anchoring device of claim 1 , wherein the anchors are formed of metal or polymer.5. The anchoring device of claim 1 , further comprising one or more radiopaque markers positioned thereon.6. The anchoring device of claim 1 , wherein the device has two anchors and the fixed ends of the anchors are spaced at least 90 degrees apart.7. The anchoring device of claim 1 , wherein the device has two anchors and the fixed ends of the anchors are spaced about 120 degrees apart.8. The anchoring device of claim 1 , wherein the device has two anchors claim 1 , one of which is longer than the other.9. The anchoring device of claim 1 , wherein the device has three anchors.10. The anchoring device of claim 1 , wherein the slots have a length of ...

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Номер записи: 30
11-07-2013 дата публикации

HEART VALVE PROSTHESIS

Номер: US20130178931A1
Автор: Fargahi Amir
Принадлежит: BIOTRONIK AG

The invention relates to a heart valve prosthesis comprising biological material or plastic material, having a suture or knot which comprises an X-ray visible material and the position of which identifies the valve plane. 1. A heart valve prosthesis made of biological material or plastic material , having a suture section including at suture or knot which comprises an X-ray visible metal wire wherein a position of the suture section identifies a plane of the heart valve prosthesis.2. The heart valve prosthesis according to claim 1 , wherein the metal wire comprises or is coated with at least one of the elements gold claim 1 , platinum claim 1 , tantalum and tungsten.3. A heart valve prosthesis according to claim 1 , wherein the metal wire has a diameter ranging between about 20 and about 200 μm.4. A heart valve prosthesis according to claim 1 , wherein the suture has a portion produced from a different suture material.5. A heart valve prosthesis according to claim 1 , wherein the suture comprises a double suture claim 1 , an overlap suture claim 1 , or an overlock suture.6. A heart valve prosthesis according to claim 1 , wherein the heart valve prosthesis comprises a base body claim 1 , and three valvular cusps claim 1 , each valvular cusp having the suture section.7. A heart valve prosthesis according to claim 6 , wherein the valvular cusps are sewn into the base body with the suture.8. A heart valve prosthesis according to claim 1 , wherein the suture is placed such that a predefined end thereof identifies a position of the valve plane.9. A heart valve prosthesis according to claim 1 , wherein the suture section includes the knot.10. A heart valve prosthesis according to claim 1 , which is sewn into a vascular stent claim 1 , wherein a suture connecting the heart valve prosthesis to the vascular stent is arranged in a corresponding manner to a position of the valve plane and is produced from the X-ray visible metal wire.11. A heart valve prosthesis according to ...

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Номер записи: 31
18-07-2013 дата публикации

Prosthetic heart valve including stent structure and tissue leaflets, and related methods

Номер: US20130184812A1
Автор: Bob Allan, Chad Cai, Lise LaChance, Paul Edward Ashworth, Peter Nicholas Braido, Steven D. Kruse
Принадлежит: St Jude Medical LLC

A method of making a prosthetic heart valve may include providing an annular stent having a plurality of annularly spaced commissure portions having tips, covering each of the tips with a first fabric cover, covering the first fabric covers and the remainder of the stent with a second fabric cover, covering the second fabric cover with a first tissue membrane, and covering the outside of the first tissue membrane with a second tissue membrane, the second tissue membrane forming leaflet portions that extend inwardly between the commissure portions.

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Номер записи: 32
18-07-2013 дата публикации

METHODS OF IMPLANT OF A HEART VALVE WITH A CONVERTIBLE SEWING RING

Номер: US20130184814A1
Автор: Huynh Van Le, Johnson Derrick, Scott Michael J.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

A sewing ring for prosthetic heart valves that is connected and configured to pivot outward. A biocompatible fabric covering surrounds at least a portion of the sewing ring, and the ring may be exclusively connected to a stent with the fabric. The sewing ring may be generally planar and of uniform thickness, or may be of varying thickness. The fabric may be used to encompass both the stent and the sewing ring, and may be a single piece. A seam may be provided in the fabric as a discrete pivoting line. The sewing ring may be convertible between bi-stable positions. The ring may extend outward in a frusto-conical shape so as to enable inversion between a position facing the inflow end of the valve and a position facing the outflow end of the valve. A method of implantation, and a method of assembly of the heart valve is also provided. 1. A method of implanting at a heart valve annulus a prosthetic heart valve having an inflow end and an outflow end , that define a flow direction through the valve , and a sewing ring attached to a periphery thereof , comprising:orienting the sewing ring to extend generally against the flow direction;attaching the sewing ring to the annulus; andre-positioning the valve with respect to the attached sewing ring so that the sewing ring is oriented to extend generally with the flow direction.2. The method of claim 1 , wherein the step of attaching comprises suturing the sewing ring to the annulus by first passing sutures through the annulus claim 1 , extending the sutures out of the surgical field claim 1 , and passing the sutures through the sewing ring while it is oriented to extend generally against the flow direction.3. The method of claim 1 , wherein the heart valve has a structural stent claim 1 , wherein the sewing ring comprises a suture-permeable insert ring and a fabric cover claim 1 , and the fabric cover surrounds the insert ring and connects the insert ring to the stent periphery at a single seam claim 1 , the seam defining a ...

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Номер записи: 33
25-07-2013 дата публикации

METHOD TO REDUCE MITRAL REGURGITATION BY CINCHING THE COMMISSURE OF THE MITRAL VALVE

Номер: US20130190863A1
Автор: Call Aaron M., Lane Joseph P.
Принадлежит: Mitralign, Inc.

Methods of repairing the mitral valve and reducing mitral regurgitation. One method includes securing a first tissue anchor to a position on a posterior portion of the annular tissue of the mitral valve and a second tissue anchor to a position on an anterior portion of the annular tissue of the mitral valve. At least one tensile member spans between the first and second tissue anchors and across the orifice of the mitral valve. When tension is applied to the at least one tensile member, the posterior portion of the annular tissue is pulled toward the anterior portion. 1. A method of repairing a mitral heart valve , the mitral heart valve having posterior and anterior leaflets forming an orifice therebetween , an annulus surrounding the posterior and anterior leaflets , and posterior and anterior commissures where the posterior and anterior leaflets join the annulus , the method comprising:(a) securing a first tissue anchor to a position on a posterior portion of the annulus between the posterior and anterior commissures;(b) securing a second tissue anchor to a position on an anterior portion of the annulus between the posterior and anterior commissures;(c) spanning at least one tensile member between the first and second tissue anchors and across the orifice of the mitral valve; and(d) applying tension to the at least one tensile member, thereby pulling the posterior portion of the annulus toward the anterior portion of the annulus.2. The method according to claim 1 , wherein the at least one tensile member is a suture claim 1 , a wire claim 1 , or a staple base.3. The method according to further comprising:maintaining the tension applied to the at least one tensile member with a suture locker.4. The method according to claim 3 , wherein the suture locker includes a locker body and a slidable member coupled to the locker body for securing the at least one tensile member claim 3 , the slidable member having a latent condition wherein the at least one tensile member ...

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Номер записи: 34
25-07-2013 дата публикации

Annuloplasty prostheses and surgical techniques

Номер: US20130190864A1
Автор: Aram K. Smolinsky
Принадлежит: Individual

An annuloplasty prosthesis is provided that includes a skeleton and a sleeve. The skeleton comprises a rigid posterior bar segment, which has first and second bar ends. The sleeve (a) comprises a flexible and substantially non-extensible fabric material, (b) covers the rigid posterior bar segment, (c) includes a first portion that extends at least 20 mm beyond the first bar end and a second portion that extends at least 25 mm beyond the second bar end, and (d) has a plurality of visually-sensible fiducial designators at respective longitudinal locations distributed along at least a portion of the sleeve, which fiducial designators are arranged to indicate a longitudinal center of the rigid posterior bar segment. The prosthesis is rigid along the rigid posterior bar segment, and is flexible or semi-rigid along at least 75% of the first portion of the sleeve and along at least 75% of the second portion of the sleeve.

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Номер записи: 35
25-07-2013 дата публикации

ANNULOPLASTY RING WITH INTRA-RING ANCHORING

Номер: US20130190866A1
Автор: CABIRI Oz, GROSS Yossi, ZIPORY Yuval
Принадлежит: VALTECH CARDIO, LTD.

A method includes positioning an anchor deployment manipulator at least partially within a lumen of a sleeve of an annuloplasty ring, the sleeve having a lateral wall shaped to define the lumen, and the lumen extending longitudinally along a length of the sleeve. A portion of the sleeve that contains a distal end of the deployment manipulator is placed into an atrium in a vicinity of an annulus of an atrioventricular valve. An anchor is deployed from the distal end of the deployment manipulator through the lateral wall of the sleeve into cardiac tissue, while the distal end of the deployment manipulator is positioned such that a central longitudinal axis of the deployment manipulator through the distal end of the deployment manipulator forms an angle of between 45 and 90 degrees with the lateral wall of the sleeve at a point at which the anchor penetrates the lateral wall. 123-. (canceled)24. A method comprising:positioning an anchor deployment manipulator at least partially within a lumen of a sleeve of an annuloplasty ring, the sleeve having a lateral wall shaped to define the lumen, and the lumen extending longitudinally along a length of the sleeve;placing, into an atrium of a subject in a vicinity of an annulus of an atrioventricular valve, at least a portion of the sleeve that contains a distal end of the deployment manipulator; anddeploying at least one anchor from the distal end of the deployment manipulator through the lateral wall of the sleeve into cardiac tissue of the subject, while the distal end of the deployment manipulator is positioned such that a central longitudinal axis of the deployment manipulator through the distal end of the deployment manipulator forms an angle of between 45 and 90 degrees with the lateral wall of the sleeve at a point at which the anchor penetrates the lateral wall.25. The method according to claim 24 , wherein deploying comprises deploying the at least one anchor while the angle is between 75 and 90 degrees.2627-. ( ...

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Номер записи: 36
01-08-2013 дата публикации

ADJUSTMENT SUTURE MARKERS FOR ADJUSTABLE ANNULOPLASTY RING

Номер: US20130197632A1
Автор: Kovach Melinda K., Li Xuemei, Volovsek Rebecca
Принадлежит: St. Jude Medical, Cardiology Division, Inc.

An adjustable annuloplasty ring includes a body in the form of an endless loop having an internal lumen therethrough, an adjustment suture extending through at least a portion of the internal lumen, a first portion of the suture exiting the lumen through a first opening in the body and a second portion of the suture exiting the lumen through a second opening in the body, and a first adjustment marker on the first portion of the suture outside of the body. The suture may be adapted to reduce the length of the body around the loop when tightened. 1. An adjustable annuloplasty ring , comprising:a body in the form of an endless loop having an internal lumen therethrough;an adjustment suture extending through at least a portion of the internal lumen, a first portion of the suture exiting the lumen through a first opening in the body and a second portion of the suture exiting the lumen through a second opening in the body, the suture adapted to reduce the length of the body around the loop when tightened; anda first adjustment marker on the first portion of the suture outside of the body.2. The adjustable annuloplasty ring of claim 1 , wherein the first opening is spaced from the second opening.3. The adjustable annuloplasty ring of claim 2 , further comprising a second adjustment marker on the second portion of the suture outside of the body.4. The adjustable annuloplasty ring of claim 1 , wherein the first adjustment marker is formed from a material applied to a surface of the suture claim 1 , the material being selected from the group consisting of ink claim 1 , paint claim 1 , and an adhesive.5. The adjustable annuloplasty ring of claim 1 , wherein the first adjustment marker is formed by a permanent deformation on a surface of the suture.6. The adjustable annuloplasty ring of claim 5 , wherein the permanent deformation is a burn mark.7. The adjustable annuloplasty ring of claim 1 , wherein the first adjustment marker is formed by a stitch on a surface of the suture.8 ...

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Номер записи: 37
08-08-2013 дата публикации

Stentless Support Structure

Номер: US20130204357A1
Автор: Christopher M. Banick, Gary A. Thill, John P. Gainor, Robert Foster Wilson
Принадлежит: HLT Inc

A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.

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Номер записи: 38
08-08-2013 дата публикации

Semi-flexible annuloplasty ring

Номер: US20130204361A1
Автор: David H. Adams, John T.M. Wright
Принадлежит: Medtronic ATS Medical Inc

An annuloplasty ring for attachment to an annulus of a tricuspid valve comprises an elongate tube of suturable material comprising a central segment and first and second end segments. An arcuate stiff ener is received in the central segment of the tube and extends the length thereof. The arcuate stiffener is circumferentially confined within the central segment to prevent circumferential movement of the stiffener relative to the tube. The first and second end segments of the tube lack a stiffener and are axially deformable.

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Номер записи: 39
15-08-2013 дата публикации

FLEXIBLE ANNULOPLASTY RING

Номер: US20130211512A1
Автор: Abram Tim, Crockett Bob, Migliazza John F.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. In addition, selective placement of point-welds or other such control points locally control other parameters such as the amount and direction of displacement as the ring undergoes external loading. Cable with well-placed control points result in a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as for example 1 cm×1 cm, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle and allowing for asymmetrical deflection to be designed into the product. 1. An annuloplasty ring , comprising:a flexible core member defining the peripheral shape of the ring, the flexible core member comprising a multi-stranded braided cable formed of multiple wire strands wound into multi-strand braids with the multi-strand braids being braided into the multi-stranded braided cable and having a first elastic modulus; anda suture-permeable outer covering encasing the flexible core member.2. The annuloplasty ring of claim 1 , wherein the multi-stranded braided cable has at least seven multi-strand braids in cross-section.3. The annuloplasty ring of claim 2 , wherein the multi-stranded braided cable has a 7×7 cross-sectional braid pattern.4. The annuloplasty ring of claim 2 , wherein the multi-stranded braided cable has a 7×19 cross-sectional braid pattern.5. The annuloplasty ring of claim 2 , wherein the multi-stranded braided cable has a 19×7 cross-sectional braid pattern.6. The annuloplasty ring of claim 2 , wherein the multi-stranded braided cable has a 7×7×7 cross-sectional braid pattern.7. The ...

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Номер записи: 40
15-08-2013 дата публикации

Method and apparatus for repairing a mitral valve

Номер: US20130211513A1
Автор: Jonathan M. Rourke, Stanley B. Kyi
Принадлежит: MITRASPAN Inc

A method for repairing a mitral valve, the method comprising: positioning a crossing guidewire across the mitral valve, the crossing guidewire passing through the annulus of the mitral valve at a first location and passing through the annulus of the mitral valve at a second location; using the crossing guidewire to position a spanning implant across the mitral valve, with the spanning implant extending from the first location to the second location; anchoring the spanning implant at the first location; tensioning the spanning implant so as to draw the first location and the second location together; and anchoring the spanning implant at the second location.

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Номер записи: 41
29-08-2013 дата публикации

PERCUTANEOUS ANNULOPLASTY SYSTEM WITH ANTERIOR-POSTERIOR ADJUSTMENT

Номер: US20130226289A1
Автор: Cao Hung H., DuMontelle Jeffrey P., Packham Victor S., Shaolian Samuel M., YELLIN Nadav
Принадлежит: Valcare, Inc.

Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow body member including a plurality of regions. Adjacent regions cooperate with one another to change the body member from an elongate insertion geometry to an annular operable geometry. Adjacent regions are coupled by a biasing element or a stepped connector to allow expansion to an expanded state and contraction to a contracted state in the annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the body member and having a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. An angled ring closure lock allows coupling of the ends of an annuloplasty ring at an apex of a D-shape annular operable geometry. 1. An adjustable annuloplasty ring for percutaneous , transcatheter heart valve repair , the annuloplasty ring comprising:a body member that is transitionable from an elongate insertion geometry to an annular operable geometry, the elongate insertion geometry to allow percutaneous passage of the annuloplasty ring, via a catheter, into a heart of a patient, and the annular operable geometry having an expanded state to conform to an annulus of a target valve of the heart and a contracted state to reduce a diameter of the annulus of the target valve;a plurality of anchors percutaneously deployable from the body member in the annular operable geometry to engage the annulus of the target valve;a biasing element disposed between a first region and a second region of the body member, the biasing element configured to be expanded to increase an anterior-posterior distance of the annuloplasty ring in the annular operable geometry to the expanded state in abutment with the annulus of the target valve, such that subsequent deployment of the plurality of ...

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Номер записи: 42
29-08-2013 дата публикации

Methods, devices, and systems for percutaneously anchoring annuloplasty rings

Номер: US20130226290A1
Автор: Jeffrey P. DuMontelle, Nadav Yellin, Samuel M. Shaolian
Принадлежит: Individual

Apparatus, systems, and methods are provided for percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer tube, an inner body member, and an anchor deployment system. The outer tube includes a plurality of windows and has an axis along its length. The internal body member includes a plurality of anchors formed perpendicular to the axis. The anchor deployment system selectively rotates the internal body member with respect to the axis of the outer tube. The rotation deploys the plurality of anchors through the plurality of windows.

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Номер записи: 43
05-09-2013 дата публикации

INTRA-ATRIAL IMPLANTS MADE OF NON-BRAIDED MATERIAL

Номер: US20130231737A1
Автор: Celermajer David, Forcucci Stephen J., McNamara Edward, Sugimoto Hiroatsu
Принадлежит: DC DEVICES, INC.

Several unique intra-cardiac pressure devices, placement catheters, methods of placement and methods of treating heart failure are presented. The intra-cardiac pressure devices presented allow sufficient flow from the left atrium to the right atrium to enable the relief of elevated left atrial pressure and resulting patient symptoms. The intra-cardiac pressure devices are made of a non-braided material. 1. A device for implanting in an opening in a septal wall in a heart of a patient , comprising:i. a first annular flange comprising a plurality of flange segments, each of said flange segments of the first annular flange having a first end and a second end;ii. a second annular flange comprising a plurality of flange segments, each of said flange segments of the second annular flange having a first and a second end, at least one of said flange segments of said second annular flange comprising a end adapted to be substantially parallel with and contact the septal wall when deployed; and wherein the first ends of the first annular flange and the first ends of the second annular flange are contiguous with and define the core segment,', 'wherein at least one of the flange segments of the second annular flange includes a first section that extends into the atrium and a second section that extends from the first section toward the septal wall,', 'wherein the second end of the at least one of the flange segments of the second annular flange is adapted to be in contact with the septal wall,', 'wherein at least a portion of at least one of said flange segments is more flexible than a portion of said core segment, and', 'wherein the core segment is collapsible, enabling the core segment to have a second diameter less than the first diameter thereby enabling percutaneous delivery., 'iii. a core segment having a first diameter when deployed, said core segment defining a passage adapted to permit fluid to flow therethrough from one side of said septal wall to another side of said ...

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Номер записи: 44
12-09-2013 дата публикации

METHOD FOR ANCHORING A MITRAL VALVE

Номер: US20130238089A1
Автор: Gelbart Daniel, Lichtenstein Samuel Victor
Принадлежит: KARDIUM INC.

An artificial mitral valve is anchored in the left atrium by placing the valve between the annulus of the natural mitral valve and an artificial annulus. The artificial annulus is formed by inserting a tool into the coronary sinus, and adjusting the tool to force the wall of the left atrium to form an annulus above the artificial valve, this locking it in place and forming a hemostatic seal. 1. A method for anchoring an artificial mitral valve in a left atrium of a heart , the method comprising:deploying the artificial mitral valve in the left atrium of the heart;positioning the artificial mitral valve above a natural annulus of a natural mitral valve in the heart; andshaping an atrial wall to form an artificial annulus to anchor artificial mitral valve.2. The method of wherein shaping an atrial wall to form an artificial annulus includes shaping the atrial wall to form the artificial annulus at least one of above or around the artificial mitral valve.3. The method of claim 1 , further comprising:percutaneously deploying the artificial mitral valve in the left atrium.4. The method of further comprising:inserting a tool in the coronary sinus to at least partially form the artificial annulus.5. The method of wherein deploying the artificial mitral valve includes expanding a balloon.6. The method of claim 1 , further comprising:permanently installing a tool in the coronary sinus to at least partially form the artificial annulus.7. A method to replicate a function of a natural mitral valve in a left atrium of a heart claim 1 , the natural mitral valve about which a coronary sinus of the heart at least partially extends claim 1 , the method comprising:inserting an artificial mitral valve inside an opening formed by the natural mitral valve in the left atrium of the heart;inserting an elongate member in a flexible state at least partially into the coronary sinus while in the flexible state such that the elongate member at least partially encircles a portion of the ...

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Номер записи: 45
26-09-2013 дата публикации

Heart valve chordae replacement methods and apparatus

Номер: US20130253639A1
Автор: Yousef F. Alkhatib
Принадлежит: St Jude Medical LLC

Apparatus for attaching a prosthetic tether between a leaflet of a patient's heart valve and another portion of the patient's heart to help prevent prolapse of the leaflet and/or to otherwise improve leaflet function. The apparatus can be used with relatively low invasiveness of the patient's body. The apparatus releasably clamps the leaflet during attachment of the tether to the leaflet. The apparatus may include an integrated display for indicating how extensively the leaflet is being clamped, as well as structure for stabilizing the leaflet for better clamping. The apparatus may enter the heart through an aperture in the wall of the heart, and may include structure for helping to reduce blood leakage from that aperture. The apparatus may be able to enter the heart by following a guide wire. The apparatus may include various means for attaching the tether to the leaflet.

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Номер записи: 46
26-09-2013 дата публикации

Collapsible valve prosthesis

Номер: US20130253643A1
Автор: Antonella Orecchia, Giovanni Rolando, Massimiliano Ares, Monica Achiluzzi, Paolo Gaschino
Принадлежит: Sorin Group Italia SRL

A collapsible valve prosthesis includes an armature and a set of prosthetic valve leaflets supported by the armature. The armature is expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, and includes a tubular intra-annular portion defining a blood flow lumen having an inflow side and an outflow side. The tubular intra-annular portion supports the prosthetic valve leaflets in the blood flow lumen and is provided with outward formations for coupling with the natural valve site. The armature includes an over-annular portion linked to the intra-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. The armature may also include an under-annular portion to extend collar-like at the outflow side of the blood flow lumen. The prosthesis may permit mitral valve replacement (MVR) without removing the native valve leaflets and the chordae tendineae.

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Номер записи: 47
24-10-2013 дата публикации

Side-entry knotless suture anchoring clamps and deployment tools

Номер: US20130282028A1
Автор: Brian S. Conklin, Donald E. Bobo, Jr., Louis A. Campbell, Salvador Marquez
Принадлежит: Edwards Lifesciences Corp

Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.

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Номер записи: 48
31-10-2013 дата публикации

Percutaneous transcatheter repair of heart valves

Номер: US20130289718A1
Автор: Brian C. Gray, Hung H. Cao, Maurice Buchbinder, Ross Tsukashima, Samuel M. Shaolian, Victor S. Packham
Принадлежит: Valcare Inc

Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow member including a plurality of segments. Adjacent segments cooperate with one another to change the outer hollow member from an elongate insertion geometry to an annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the outer hollow member. The internal anchor member includes a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. The internal anchor member is configured to move the plurality of anchors with respect to a plurality of windows in the outer hollow member to selectively deploy the plurality of anchors through the respective windows.

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Номер записи: 49
31-10-2013 дата публикации

PROSTHETIC DEVICE FOR HEART VALVE REINFORCEMENT AND REMODELING PROCEDURES

Номер: US20130289719A1
Автор: Dobrilovic Nikola
Принадлежит:

A prosthetic heart valve reinforcement ring is disclosed, which includes a ring body sized and dimensioned to fit an annulus of a heart valve. The ring body has an inner surface. A plurality of suture engaging features is on the inner surface of the ring body. A method of reinforcing a heart valve is also disclosed. Sutures are provided around an annulus of a heart valve. The proper size of the heart valve is determined by inserting a prosthetic ring around the annulus of the heart valve. The fit of the prosthetic ring is tested by attaching the sutures to the suture engaging features of the prosthetic ring. The fit of the prosthetic ring is adjusted by manipulating the sutures about the suture engaging features. The sutures are tied, securing the prosthetic ring in place. 1. A prosthetic heart valve reinforcement ring , comprising a ring body sized and dimensioned to fit an annulus of a heart valve , the ring body having an inner surface , a plurality of suture engaging features on the inner surface of the ring body.2. The prosthetic heart valve reinforcement ring of claim 1 , wherein the plurality of suture engaging features comprises a groove configured and arranged to grip a suture.3. The prosthetic heart valve reinforcement ring of claim 2 , wherein the grooves are formed on an inner surface of the ring body.4. The prosthetic heart valve reinforcement ring of claim 2 , wherein the grooves have a rubber coating.5. The prosthetic heart valve reinforcement ring of claim 1 , wherein the plurality of suture engaging features comprises a notch.6. The prosthetic heart valve reinforcement ring of claim 1 , wherein the plurality of suture engaging features comprises a stay.7. The prosthetic heart valve reinforcement ring of claim 6 , wherein the stay has a hooked end.8. The prosthetic heart valve reinforcement ring of claim 7 , wherein the hooked end is formed by a recess within the ring body.9. The prosthetic heart valve reinforcement ring of claim 7 , wherein the ...

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Номер записи: 50
31-10-2013 дата публикации

PROSTHETIC DEVICE FOR HEART VALVE REINFORCEMENT AND REMODELING PROCEDURES

Номер: US20130289720A1
Автор: Dobrilovic Nikola
Принадлежит:

A prosthetic heart valve reinforcement ring is disclosed. The prosthetic includes an outer ring sized and dimensioned to fit around an annulus of a heart valve and an inner ring configured and arranged to couple to the outer ring. The inner ring and the outer ring have complimentary mating formations configured and arranged to grip sutures therebetween. A method of reinforcing heart valve is also disclosed. Sutures are provided around an annulus of a heart valve. The sutures are corralled within an outer sizing ring. The outer sizing ring is placed around the annulus of the heart valve. An inner sizing ring is inserted within the outer ring, locking the sutures. The sutures are adjusted and the heart valve is tested for a proper fit. The outer sizing ring is removed and a prosthetic ring is placed over the inner sizing ring, locking the sutures. The sutures are tied. 1. A method of reinforcing heart valve , comprisingproviding sutures around an annulus of a heart valve;corralling sutures within an outer sizing ring;placing an outer sizing ring around the annulus of the heart valve;inserting an inner sizing ring within the outer ring, locking the sutures therebetween;adjusting the sutures to achieve a proper fit;testing the heart valve for a proper fit;removing the outer sizing ring after the a proper fit has been determined;placing a prosthetic ring over the inner sizing ring, locking the sutures therebetween; andtying the sutures.2. The method of claim 1 , further comprising removing the inner sizing ring.3. The method of claim 2 , wherein the inner sizing ring is removed after the sutures are tied.4. The method of claim 1 , further comprising tying the sutures to the prosthetic ring.5. The method of claim 1 , further comprising tying the sutures both the inner sizing ring and prosthetic ring.6. The method of claim 1 , further comprising using a knot-tying device to tie the sutures.7. The method of claim 1 , further comprising wrapping sutures around the prosthetic ...

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Номер записи: 51
14-11-2013 дата публикации

Left Heart Assist Device and Method

Номер: US20130304198A1
Автор: Solem Jan Otto
Принадлежит: Synergio AG

A device, a kit and a method is presented for permanently augmenting the pump function of the left heart. The mitral valve plane is assisted in a movement along the left ventricular long axis during each heart cycle. The very close relationship between the coronary sinus and the mitral valve is used by various embodiments of a medical device providing this assisted movement. By means of catheter technique an implant is inserted into the coronary sinus, the device is augmenting the up and down movement of the mitral valve and thereby increasing the left ventricular diastolic filling when moving upwards and the piston effect of the closed mitral valve when moving downwards. 1. A medical device for intra-cardiac blood circulation of a heart of a patient comprising:a first anchor unit implantable in a cardiac vessel of said heart in proximity to a mitral valve (MV),a force generating unit in communication with said first anchor unit, said force generating unit being operative to generate a force for assisting said blood circulation according to a cardiac cycle of said heart, andwherein said first anchor unit is configured to receive said force in such a manner so as to cause movement of said mitral valve in a mitral valve plane in a direction to and/or from an apex of said heart.2. The device of claim 1 , wherein said movement extends substantially along a long axis of the left ventricle of said heart claim 1 , and wherein said movement is provided during systole towards an apex of said heart and/or during diastole away from said apex of said heart.3. The device of claim 2 , wherein said movement is provided during systole towards said apex of said heart and during diastole away from said apex.4. The device of claim 1 , wherein said movement is provided along a short axis of a left ventricle claim 1 , transversal to said long axis so as to thereby assist a natural inwards and outwards movement of a lateral left ventricular wall relative to an intra-ventricular septum.5. ...

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Номер записи: 52
14-11-2013 дата публикации

PROSTHETIC HEART VALVE DEVICES, PROSTHETIC MITRAL VALVES AND ASSOCIATED SYSTEMS AND METHODS

Номер: US20130304200A1
Автор: GIFFORD, III Hanson, McLean Matt, Morriss John
Принадлежит: Foundry Newco XII, Inc.

Devices and methods for implantation at a native mitral valve having a non-circular annulus and leaflets. One embodiment of the device includes a valve support having a first region configured to be attached to a prosthetic valve with a plurality of prosthetic leaflets and a second region. The device can further include an anchoring member having a longitudinal dimension and including a first portion configured to contact tissue at the non-circular annulus, a second portion configured to be attached to the valve support, and a lateral portion between the first portion and the second portion. The second portion of the anchoring member is attached to the second region of the valve support while in a low-profile configuration in which the anchoring member and the valve support are configured to pass through vasculature of a human. The lateral portion is transverse to the longitudinal dimension. The anchoring member and the valve support are configured to move from the low-profile configuration to an expanded configuration in which the first portion of the anchoring member at least partially adapts to the non-circular annulus of the native mitral valve and the first region of the valve support is spaced inwardly from the first portion of the anchoring member relative to the longitudinal dimension of the anchoring member such that a shape of the first region of the valve support is at least partially independent of a shape of the first portion of the anchoring member. 1. A prosthetic heart valve device for treating a native heart valve having a native annulus and native leaflets , comprising:a valve support having an upstream region and a downstream region relative to blood flow direction through a native heart valve of a human heart, the upstream region being configured to support a prosthetic valve, the prosthetic valve having a plurality of leaflets and having an undeformed shape in which the leaflets coapt sufficiently to prevent backflow through the prosthetic valve ...

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Номер записи: 53
14-11-2013 дата публикации

APPARATUS AND METHODS FOR REPAIR OF A CARDIAC VALVE

Номер: US20130304201A1
Автор: Goodin Mark S., Navia Jose A., Navia Jose L.
Принадлежит: THE CLEVELAND CLINIC FOUNDATION

An annuloplasty ring for repairing a cardiac valve includes an expandable support member having oppositely disposed proximal and distal end portions and a main body portion between the end portions. The proximal end portion of the support member includes a plurality of wing members that extend from the main body portion. Each of the wing members includes at least one hook member for embedding into a cardiac wall and the valve annulus to secure the annuloplasty ring in the valve annulus. The annuloplasty ring may be expanded into full contact engagement with the annulus of the cardiac valve by an inflatable balloon. Methods for repairing a cardiac valve using the annuloplasty ring are also provided. 1. An annuloplasty ring for repairing a cardiac valve , said annuloplasty ring comprising:an expandable support member having oppositely disposed proximal and distal end portions and a main body portion between said end portions, said proximal end portion of said support member comprising a plurality of wing members that extend from said main body portion; andeach of said wing members including at least one hook member for embedding into a cardiac wall and the annulus of the cardiac valve to secure said annuloplasty ring in the annulus.2. The annuloplasty ring of wherein said hook members claim 1 , when embedded into the cardiac wall and the valve annulus claim 1 , extend distally from said wing members.3. The annuloplasty ring of wherein said main body portion has a concave cross-sectional shape for conforming to the convex shape of the valve annulus.4. The annuloplasty ring of wherein each of said wing members has a concave cross-sectional shape for conforming to the convex shape of the valve annulus.5. The annuloplasty ring of wherein said main body portion and said wing members are resiliently bendable from said concave cross-sectional shapes into flatter cross-sectional shapes for delivery and placement of said annuloplasty ring.6. The annuloplasty ring of further ...

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Номер записи: 54
28-11-2013 дата публикации

RAPID DEPLOYMENT PROSTHETIC HEART VALVES

Номер: US20130317598A1
Автор: Bakis George, Bash Assaf, Benichou Netanel, Bourang Henry, Keidar Yaron, Rowe Stanton J., Spenser Benjamin, Wood Larry L.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be expandable or a non-expandable type. 1. A prosthetic heart valve , comprising:a non-expandable/non-collapsible prosthetic heart valve member having a sewing ring on an inflow end;an expandable anchoring member sized to contact a heart valve annulus in an expanded state and being connected to the sewing ring.2. The heart valve of claim 1 , wherein the anchoring member comprises a tubular structure having connectors adapted to engage the sewing ring.3. The heart valve of claim 2 , wherein the connectors comprise prongs that change shape and engage the base ring.4. The heart valve of claim 2 , wherein the prongs are shaped to wrap around the base ring.5. The heart valve of claim 1 , wherein the anchoring member comprises a stent having a wider outflow end than an inflow end claim 1 , and wherein the valve sewing ring is sized to fit within the outflow end of the stent.6. The heart valve of claim 1 , wherein the anchoring member comprises a tubular structure having a suture-permeable fixation ring attached thereto claim 1 , wherein the valve member connects to the anchoring member via sutures looped between the valve sewing ring and the fixation ring. The present ...

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Номер записи: 55
28-11-2013 дата публикации

Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods

Номер: US20130317603A1
Автор: Hanson Gifford, III, John Morriss, Matt McLean
Принадлежит: Foundry Newco XII Inc

Devices and methods for implantation at a native mitral valve having a non-circular annulus and leaflets. One embodiment of the device includes a valve support having a first region configured to be attached to a prosthetic valve with a plurality of prosthetic leaflets and a second region, and an anchoring member having a longitudinal dimension with a first portion configured to contact tissue at the non-circular annulus, a second portion configured to be attached to the valve support, and a lateral portion transverse to the longitudinal dimension between the first portion and the second portion. The anchoring member and the valve support are configured to move from a low-profile configuration to an expanded configuration in which a shape of the first region of the valve support is at least partially independent of a shape of the first portion of the anchoring member.

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Номер записи: 56
05-12-2013 дата публикации

Post-operative adjustment tool, minimally invasive attachment apparatus, and adjustable tricuspid ring

Номер: US20130325118A1
Автор: Richard G. Cartledge
Принадлежит: St Jude Medical Cardiology Division Inc

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.

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Номер записи: 57
12-12-2013 дата публикации

Method and Device for Percutaneous Valve Annuloplasty

Номер: US20130331864A1
Автор: Ana Menk, Damian Jelich, Gilbert Tang, Jason Quill
Принадлежит: MEDTRONIC INC

A delivery system for delivery of a radially expandable device to an implantation site in a patient, the delivery system including an elongated tubular member comprising a distal tip and an outer surface, first and second balloon portions spaced proximally from each other and the distal tip along a length of the tubular member, an annular space between the first and second balloon portions, a plurality of clip deployment tubes extendably moveable relative to the outer surface of the tubular member, and a plurality of clips, wherein each clip is moveable within a length of one of the clip deployment tubes between a retracted position and a deployed position.

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Номер записи: 58
12-12-2013 дата публикации

COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES WITH NON-EXPANDING STENT POSTS AND RETRIEVAL FEATURES

Номер: US20130331933A1
Автор: Alkhatib Yousef F.
Принадлежит: ST. JUDE MEDICAL, INC

A frame structure for a collapsible and re-expandable prosthetic heart valve. The frame structure includes an annular annulus portion that is configured for implanting in or near a patient's native heart valve annulus. This annulus portion of the frame structure may include a plurality of annularly spaced commissure post structures interconnected by connecting structures. The commissure post structures may be more resistant to annular collapse than the connecting structures. In the case of a prosthetic aortic valve, the frame structure may also include an annular aortic portion. The aortic portion may include a plurality of attachment points (for tethers) closest to the annulus portion. Such attachment points and tethers can facilitate re-collapse of a partly deployed valve in the event of a need to reposition or remove the valve. 1. (canceled)2. A frame structure for a prosthetic aortic heart valve , comprising:an annulus portion that is annular about a longitudinal axis and that is annularly collapsible and re-expandable, the annulus portion including a plurality of annularly spaced commissure post structures extending in a first direction parallel to the longitudinal axis, and a plurality of open-centered, closed perimeter first cells annularly positioned between the commissure post structures;an aortic portion that is annular about the longitudinal axis and annularly collapsible and re-expandable, the aortic portion being spaced from the annulus portion in the first direction;a plurality of strut members each having one end connected to the annulus portion and another end connected to a point on the aortic portion, for each of the points the aortic portion including a pair of arm members that begin at the point and diverge from one another in the first direction until each of the arm members connects to an arm member that started from an annularly adjacent one of the points, the aortic portion including no other structure between annularly adjacent ones of the ...

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Номер записи: 59
26-12-2013 дата публикации

MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE

Номер: US20130345797A1
Автор: Dahlgren Jonathan, Gelbart Daniel, Goertzen Douglas, To Derrick, Watkinson Kelly
Принадлежит:

A device, kit and method may employ an implantable device (e.g., annuloplasty implant) and a tool to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). Tissue anchors are guided into precise position by an intravascularly deployed anchor guide frame and embedded in an annulus. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in a generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may move a posterior leaflet anteriorly and an anterior leaflet posteriorly, improving leaflet coaptation to eliminate mitral regurgitation. 1. An implant kit comprising:a plurality of tissue anchors comprising at least a first tissue anchor, a second tissue anchor and a third tissue anchor;a percutaneous delivery system operable to at least partially embed each of the tissue anchors into a respective location about a periphery of an orifice in a tissue within a body during an implant procedure in which a location of the embedded third tissue anchor is laterally offset by a first distance from a first axis, the first axis extending between a location of the embedded first tissue anchor and a location of the embedded second tissue anchor;an implant member reconfigurable between a delivery configuration in which the implant member is manipulable to a size and dimension to be deliverable percutaneously to the tissue within the body, and an implantable configuration in which the implantable member forms a structure sufficiently rigid to affect a shape of the orifice in the tissue, the implant member further comprising a plurality of tissue anchor receivers, each of the tissue anchor receivers positioned to physically matingly ...

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Номер записи: 60
26-12-2013 дата публикации

IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN

Номер: US20130345802A1
Автор: Cartledge Richard G., Fann James I., Friedmann Josef L., Greene James L., Lee Leonard Y.
Принадлежит: St. Jude Medical, Cardiology Division, Inc.

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit he implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. 1. An implantable device system for controlling at least one of the shape and size of an anatomical structure or lumen , comprising:an implantable device adapted for attachment to an anatomical structure or lumen, said implantable device having a first band and a second band and an adjustable member configured to both increase and decrease the dimensions of the implantable device, said adjustable member configured to receive an adjustment tool;a torqueable adjustment tool configured to provide adjustment of the dimensions of the implantable device, wherein adjustment of said adjustable member adjusts the size of the implant device generally in a preferred dimension.2. The system of claim 1 , wherein the first band and the second band are overlappable.3. The system of claim 1 , wherein the first band and the second band are slidable relative to each other.4. The system of claim 1 , wherein the adjustable member is configured to pull the first band and the second band towards and away from each other.5. The system of claim 1 , wherein the at least one of said first and second bands has portions of varying durometer.6. The system of claim 1 , wherein the implantable device comprise a prosthetic heart valve.7. The system of claim 6 , wherein the prosthetic heart valve comprises an annuloplasty ring.8. An implantable device having an adjustable size or shape comprising:a first band including a terminal end having a plurality of ...

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Номер записи: 61
02-01-2014 дата публикации

CARDIAC VALVE SUPPORT STRUCTURE

Номер: US20140005778A1
Автор: Buchbinder Maurice, DUBI SHAY, EFTEL Avi, LOGAN Julie, TUBISHEVITZ AMIT
Принадлежит:

Cardiac valve supports and their methods of use. 1. A cardiac valve support adapted for endovascular delivery to a cardiac valve , comprising:first and second support elements each having a collapsed delivery configuration and a deployed configuration;and wherein at least two bridging members extend from the first support element to the second support element, said bridging members having a delivery configuration and a deployed configuration, wherein said bridging members extend radially inward from the first and second support elements in the deployed configuration.2. A cardiac valve support adapted for endovascular delivery to a cardiac valve , comprising:first and second support elements each having a collapsed delivery configuration and a deployed configuration;and wherein at least two bridging members extend from the first support element to the second support element, said bridging members having a delivery configuration and a deployed configuration, wherein said bridging members extend longitudinally, and without any appreciable radial curvature, between first and second support elements in the deployed configuration.3. The cardiac valve support of or , wherein the first and second bridging members extend from the first and second support elements about 180 degrees from one another.4. The cardiac valve support of or , wherein at least one of the first and second support elements has an annular shape.5. The cardiac valve support of or , wherein at least one of the first and second support elements has an outer perimeter that is entirely rigid.6. The cardiac valve support of or , wherein at least one portion of the inner perimeter of at least one of the support elements is elastically deformable in a radial direction.7. The cardiac valve support of or , wherein at least one of the support elements in its deployed configuration has the form of a flat annular ring , and wherein the difference (Rd) between the outer radius and the inner radius of said annular ring ...

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Номер записи: 62
02-01-2014 дата публикации

METHOD AND APPARATUS FOR HEART VALVE SURGERY

Номер: US20140005779A1
Автор: Hausen Bernard A.
Принадлежит: CARDICA, INC.

A method for heart valve surgery may include providing a cardiac valve ring and suture loops connected to the cardiac valve ring, accessing a valve annulus of the heart of the patient, stapling at least one of the sutures loop to the valve annulus, and parachuting the cardiac valve ring down the suture to the valve annulus after the stapling. The cardiac valve ring may be an annuloplasty ring, a replacement heart valve, or other medical device. 1. A surgical apparatus , comprising:a cardiac valve ring; anda plurality of suture loops connected to said cardiac valve ring.2. The apparatus of claim 1 , wherein said cardiac valve ring is an annuloplasty ring.3. The apparatus of claim 1 , wherein said cardiac valve ring is a replacement heart valve.4. The apparatus of claim 1 , wherein said cardiac valve ring includes a plurality of apertures defined therethrough and a tab associated with at least one said aperture.5. The apparatus of claim 4 , wherein at least one said aperture is substantially cylindrical.6. The apparatus of claim 1 , wherein at least one said suture loop is U-shaped.7. The apparatus of claim 1 , wherein at least one said suture loop is lasso-shaped.8. The apparatus of claim 1 , wherein at least one said length of suture is composed of polypropylene.9. A surgical apparatus claim 1 , comprising:a cardiac valve ring having a plurality of unidirectional suture holding features associated therewith; anda plurality of suture loops connected to said cardiac valve ring; wherein each said suture loop is formed from a single length of suture independent from the other said suture loops; and wherein each suture passes through at least one said unidirectional suture holding features in said cardiac valve ring.10. The apparatus of claim 9 , wherein at least one unidirectional suture holding feature comprisesan aperture defined through said cardiac valve ring, wherein one strand of said suture passes through said aperture, anda tab associated with said aperture, ...

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Номер записи: 63
09-01-2014 дата публикации

Method for Implanting a Prosthetic Mitral Valve

Номер: US20140012373A1
Автор: Chau Mark, Geist Stephen C., Hauser David L., Oba Travis, Patterson Marlowe E., Yi Seung-Beom
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

Embodiments of a method for implanting a prosthetic valve at the native mitral valve region of the heart, the prosthetic valve including a main body that is radially compressible to a radially compressed state and self-expandable from the compressed state to a radially expanded state. The prosthetic apparatus also comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body with a leaflet-receiving space between the anchor and an outer surface of the main body to receive a native valve leaflet. Apparatus for delivering and implanting the prosthetic valve are also described. 1. A method of implanting a prosthetic heart valve at the native mitral valve region of a heart , the native mitral valve having a native mitral valve orifice and native mitral valve leaflets , the method comprising:positioning a docking frame within the native mitral valve orifice such that the docking frame is secured to the native mitral valve leaflets; and thensecuring a prosthetic valve within the docking frame.2. The method of claim 1 , wherein positioning the docking frame within the native mitral valve orifice comprises delivering the docking frame into the mitral valve orifice in a radially compressed state and allowing the docking frame to self-expand to a radially expanded state contacting inner surfaces of the native mitral valve leaflets.3. The method of claim 1 , wherein the docking frame comprises an annular main body that comprises a lumen for receiving the prosthetic valve.4. The method of claim 1 , wherein positioning the docking frame within the native mitral valve orifice comprises positioning a first ventricular anchor behind the anterior native mitral valve leaflet and positioning a second ventricular anchor behind the posterior native mitral valve leaflet.5. The method of claim 4 , wherein the anterior native mitral valve leaflet is compressed between the first ventricular anchor and an outer surface of a main body of the docking ...

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Номер записи: 64
16-01-2014 дата публикации

Semi-Rigid Annuloplasty Ring and Band

Номер: US20140013602A1
Автор: Wright John T.M.
Принадлежит: Medtronic, Inc.

An annuloplasty ring comprising an elongate lube of suturable material formed into a ring. A stiffener configured to prevent axial compression and radial deformation of the ring is received in the tube in a first circumferential segment of the ring. An axial support configured to prevent axial compression of the ring and to permit radial deformation of the ring is received in the tube in a second circumferential segment of the ring. The first circumferential segment of the ring may correspond to a posterior portion of a mitral valve annulus with the first circumferential portion configured to extend between the right and the left fibrous trigones of the mitral valve annulus upon installation. The second circumferential segment of the ring may correspond to an anterior portion of a mitral valve annulus and the second circumferential segment is configured to extend between the right and left fibrous trigones of the mitral valve annulus upon installation. 113-. (canceled)14. A method of making an annuloplasty ring comprising:providing a length of a close-coiled spring;inserting a stiffener into a cavity formed by the spring coils;preventing axial movement of the stiffener within the cavity;forming the close-coiled spring into ring by securing the ends of the length of close-coiled spring together;providing a ribbon of suturable material;forming the ribbon into a ring by securing the ends of the ribbon together;placing the close-coiled spring formed into a ring into contact with the ring of suturable material; andforming the ring of suturable material into a tube surrounding the close-coiled spring.15. The method of further comprising securing the close-coiled spring to the ring of the suturable material tube to prevent circumferential movement of the close-coiled spring within the tube.16. The method of further comprising inserting the close-coiled tube within an elastomeric tube.17. The method of further comprising inserting an elastomeric core into the cavity formed ...

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Номер записи: 65
16-01-2014 дата публикации

METHODS AND DEVICES FOR MODULATION OF HEART VALVE FUNCTION

Номер: US20140018916A1
Автор: Cartledge Richard G., Chronos Nicolas A.f., Courtney Brian K., Fitzgerald Peter J., Hassan Ali, Lee Leonard Y.
Принадлежит: St. Jude Medical, Cardiology Division, Inc.

Methods and devices for modulating heart valve function are provided. In the subject methods, a heart valve is first in structurally modified. Blood flow through the structurally modified heart valve is then monitored, and the heart is paced in response to the monitored blood flow. Also provided are devices, systems and kits that find use in practicing the subject methods. The subject methods find use in a variety of applications. 1. A method of modulating the function of a cardiac valve in a heart , said method comprising:structurally altering said cardiac valve;monitoring blood flow through said structurally altered cardiac valve;andpacing said heart in response to said monitoring to modulate function of said cardiac valve.2. The method according to claim 1 , wherein said modulating results in an improvement in said cardiac valve function.3. The method according to claim 2 , wherein said cardiac valve is a mitral valve.4. The method according to claim 3 , wherein said structurally altering comprises performing an annuloplasty procedure on said mitral valve.5. The method according to claim 4 , wherein said annuloplasty procedure employs an implantable annuloplasty device.6. The method according to claim 5 , wherein said annuloplasty device is an interstitial device.7. The method according to claim 1 , wherein said monitoring employs an implanted blood flow velocity measuring device.8. The method according to claim 7 , wherein said blood flow velocity measuring device is a sonic device.9. The method according to claim 7 , wherein said blood flow velocity measuring device is an optical device.10. The method according to claim 7 , wherein said blood flow velocity measuring device is a thermal device.11. The method according to claim 7 , wherein said blood flow velocity measuring device is an electromagnetic device.12. The method according to claim 7 , wherein said blood flow velocity measuring device is in operational communication with an implanted cardiac pacing ...

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Номер записи: 66
23-01-2014 дата публикации

Cloned biological material medical device and method thereof

Номер: US20140023687A1
Автор: Keith A Raniere
Принадлежит: First Principles Inc

A medical device, said medical device, comprises: a first component having a non-biological material; a second component having a cloned biological material, said second component being attached to said first component, wherein said first component and said second component are operatively associated in a non-living medical device for at least one of treatment, diagnosis, cure, mitigation and prevention of disease, injury, handicap or condition in a living organism. In another aspect, a method comprises: preparing a cloned biological material from a tissue or an organ; attaching said biological material to a medical device; interfacing said biological material with the non-biological material; providing treatment, diagnosis, cure, mitigation and prevention of disease, injury, handicap or condition in a living organism.

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Номер записи: 67
23-01-2014 дата публикации

Systems, devices and methods for surgical and precutaneous replacement of a valve

Номер: US20140025163A1
Автор: Saimuralidhar Padala, Vinod H. Thourani
Принадлежит: EMORY UNIVERSITY

The systems, devices and methods relate surgical and percutaneous replacement of a valve. The devices may include a frame and artificial leaflets. The devices may include one frame or two frames. The devices may also include a stent device in which the implant valve device may be implanted. The devices may also include a valve retainer device.

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Номер записи: 68
23-01-2014 дата публикации

Disk-Based Valve Apparatus and Method for the Treatment of Valve Dysfunction

Номер: US20140025164A1
Автор: CHIEFFO Alaide, GRANADA Juan F., MONTORFANO Matteo
Принадлежит:

The present invention comprises a novel and safer mechanism of deployment using a self-positioning, self-centering, and self-anchoring method. To embody the present invention, a disk-based valve apparatus allowing the repositioning and retrieval of the implantable valve while working on a dysfunctional valve structure is disclosed. The disk-based valve apparatus may comprise one or more disks, either proximal or distal, a valve-housing component and a valve component. The one or more disks may be either proximal or distal, may be either connected to each other or disconnected from each other and may either be symmetrical or have different shapes and dimensions. The disk-based valve apparatus may be self anchoring, such as anchored by pressure from the one or more disk, or may be anchored using any anchoring. 1. A valve prosthesis having a constrained shape and an expanded shape , the valve prosthesis comprising a replacement valve attached to an anchor , the anchor comprising:a proximal portion adapted and configured to self-expand from the constrained shape into the expanded shape, the proximal portion comprising a plurality of wire petals of shape memory material;distal portion adapted and configured to self-expand from the constrained shape to the expanded shape; anda central portion disposed between, and connected to, the proximal portion and the distal portion, the central portion have a diameter in the expanded shape smaller than diameters of the proximal portion and the distal portion in their expanded shapes, the central portion being adapted to self-expand to move the proximal portion and the distal portion toward each other to compress native cardiac tissue between them.2. The valve prosthesis of wherein the plurality of wire petals of the proximal portion are disposed in an overlapping arrangement.3. The valve prosthesis of wherein the distal portion comprises a plurality of wire petals of shape memory material.4. The valve prosthesis of wherein the ...

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Номер записи: 69
30-01-2014 дата публикации

IMPLANTABLE DEVICES FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN

Номер: US20140031929A1
Автор: Cartledge Richard G., Lee Leonard Y.
Принадлежит: StJude Medical, Cardiology Division, Inc.

An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants area disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive producers and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like. 1. An implantable device system for controlling at least one of the shape and size of an anatomical orifice or lumen , comprising:an adjustable implantable device adapted for attachment to an anatomical orifice or lumen, said implantable device including an adjustable member configured to adjust at least one of the shape and size of the implantable device; andan adjustment tool configured to be releasably connected to the adjustable member such that the adjustment tool can be used to activate and control adjustment of the implantable device;wherein the adjustment member and the adjustment tool are configured to be attached and subsequently reattached to each other when the implantable device is positioned in situ to the anatomical orifice or lumen.2. The system of claim 1 , wherein the adjustable member includes an adjustment element configured for releasably connecting and reconnecting the adjustment tool to the adjustable member.3. The system of claim 1 , wherein the adjustable implant device comprises a prosthetic heart valve.4. The system of claim 3 , wherein the adjustable implantable device comprises an annuloplasty ring.5. The system of claim 3 , wherein the adjustment tool is mechanically connected to the adjustable member.6. An adjustable implantable device system for an anatomic orifice ...

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Номер записи: 70
30-01-2014 дата публикации

CARDIAC IMPLANT CONFIGURED TO RECEIVE A PERCUTANEOUS PROSTHETIC HEART VALVE IMPLANTATION

Номер: US20140031930A1
Автор: Keidar Yaron, Konno Mark A.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

The invention is a cardiac implant, and associated methods therefore, configured to repair and/or replace a native heart valve, and having a support frame configured to be reshaped into an expanded/changed form in order to receive and/or support an expandable prosthetic heart valve therein. The implant may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace/repair a native valve (or other prosthetic heart valve), but to assume a generally non-rigid and/or expanded/expandable form when subjected to an outward force such as that provided by a dilation balloon. The implant may be configured to have a generally D-shaped configuration when initially implanted, but to assume a generally circular form when subjected to an outward force such as that provided by a dilation balloon. 1. An annuloplasty ring comprising:a plurality of rigid sections, wherein each rigid section comprises a first end and a second end, wherein in a first configuration of the annuloplasty ring the plurality of rigid sections are assembled in end-to-end form to create an annuloplasty ring support frame, wherein in the first configuration the annuloplasty ring defines an inner orifice having a first area;a restraint configured to prevent movement of adjacent rigid sections with respect to each other, wherein the restraint is further configured to permit movement of the adjacent rigid sections with respect to each other and thereby permit transformation of the annuloplasty ring from the first configuration to a second configuration when the annuloplasty ring is subjected to a dilation force of at least 1 atm.2. The annuloplasty ring of claim 1 , wherein the restraint is configured to plastically deform when the annuloplasty ring is subjected to the dilation force of at least 1 atm.3. The annuloplasty ring of claim 2 , wherein the restraint comprises a suture claim 2 , weld claim 2 , solder claim 2 , or adhesive configured to break when ...

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Номер записи: 71
06-02-2014 дата публикации

Method for Stabilizing a Cardiac Valve Annulus

Номер: US20140039612A1
Автор: Dolan Mark
Принадлежит: Medtronic Vascular, Inc.

A method for stabilizing a cardiac valve annulus is provided. The method includes intravascularly delivering a prosthesis to a region of a cardiac valve, expanding the prosthesis to secure the prosthesis to the region of the cardiac valve, and reducing the inner diameter of the prosthesis to form the region of the cardiac valve into a predefined shape. 1. A method for stabilizing a cardiac valve annulus comprising:intravascularly delivering a prosthesis in a compressed configuration to a region of a cardiac valve;expanding an inner diameter of the prosthesis to a deployment configuration to secure the prosthesis to the region of the cardiac valve; andafter deployment, reducing the inner diameter of the prosthesis to a resting configuration to form the region of the cardiac valve into a predefined shape.2. The method of claim 1 , wherein forming the cardiac valve into a predefined shape reduces a diameter of the cardiac valve annulus.3. The method of claim 1 , wherein the prosthesis is self-expandable.4. The method of claim 1 , wherein the prosthesis is balloon expandable.5. The method of claim 1 , further comprising:expanding a balloon to expand the inner diameter of the prosthesis to the deployment configuration to secure the prosthesis to the region of the cardiac valve.6. The method of claim 1 , the prosthesis further comprising anchoring barbs to secure the prosthesis to a posterior portion of the cardiac valve annulus.7. The method of claim 6 , wherein the anchoring barbs are movable.8. The method of claim 7 , wherein the anchoring barbs are parallel to a central axis of the prosthesis in the compressed configuration claim 7 , andwherein the anchoring barbs are radially extended in the deployment configuration and the resting configuration.9. The method of claim 1 , wherein the prosthesis is intravascularly delivered through the femoral artery.10. The method of claim 1 , wherein the prosthesis is intravascularly delivered through the subclavian vein.11. The ...

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Номер записи: 72
06-02-2014 дата публикации

METHODS FOR REPLACING A CARDIAC VALVE

Номер: US20140039613A1
Автор: Navia Jose A., Navia Jose L., Oberti Carlos
Принадлежит:

A method for replacing a cardiac valve includes an expandable support member having oppositely disposed first and second ends, a main body portion extending between the ends, and a prosthetic valve within the main body portion. The main body portion has an annular shape for expanding into position in the annulus of the valve. The first and second ends include a plurality of upper and lower wing members movable from a collapsed condition into an extended condition for respectively engaging a first section of cardiac tissue surrounding the valve and for: engaging a portion of the native valve leaflets to pin the leaflets back against the annulus. The second end further includes at least two strut members spaced apart from each other. A respective one of the strut members is attached to at least one commissural section of the prosthetic valve to prevent prolapse of the valve leaflets. 1. A method for replacing a cardiac valve having at least two native valve leaflets , said method comprising the steps of:providing a prosthetic valve that includes an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends, a plurality of upper wing members that extend from a one end of the main body portion, and a plurality of lower wing members that extend from an opposite end of the main body portion, the second end of the support member further including at least two strut members, the prosthetic valve having at least two valve leaflets joined at two or more commissural sections, each of the commissural sections being attached to a strut member to prevent prolapse of the valve leaflets;placing the main body portion of the prosthetic valve within the annulus of the cardiac valve to be replaced;expanding the main body portion into engagement with the annulus of the cardiac valve to secure the prosthetic valve in the annulus;deploying the upper wing members from a radially collapsed condition into a radially extended ...

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Номер записи: 73
06-02-2014 дата публикации

Devices and methods for surgical and percutaneous repair of heart valve lesions

Номер: US20140039615A1
Автор: Saimuralidhar Padala, Vinod H. Thourani
Принадлежит: EMORY UNIVERSITY

The devices and methods relate to surgical and percutaneous repair of heart valve regions. The devices may be structured to conform to the desired shape of a specific patient. The devices may include a frame and an artificial body onto which leaflets of the valve may coapt or rest.

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Номер записи: 74
20-02-2014 дата публикации

Sutureless anchoring device for cardiac valve prostheses

Номер: US20140052244A1
Автор: Andrea Marchisio, Giovanni Rolando, Mauro Ercolani, Paolo Gaschino
Принадлежит: Sorin Group Italia SRL

A device for anchoring on biological tissue a prosthetic heart valve, includes first and second anchoring assemblies mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.

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Номер записи: 75
27-02-2014 дата публикации

INSTRUMENT OF PATTERNING CUSP FOR CARDIAC VALVE RECONSTRUCTION AND COMPONENT THEREOF

Номер: US20140058504A1
Автор: OZAKI Shigeyuki
Принадлежит:

In a case of repairing an aortic valve by forming a valve cusp with a biomembrane, the shape and the size of a valve cusp can be determined easily. An instrument including a valve cusp sizer for measuring the size of the valve cusp and a template for scribing lines for the shape of a valve cusp conforming to the measured size of the valve cusp, in which the valve cusp sizer has a plurality of differently-sized sizer blocks attached to each of the top ends of grip members respectively and each sizer block has an arcuate surface formed by cutting each of differently-sized circular cylinders at an angle conforming to the central angle for the commissure portions and, the template is formed with a scribing portion including a substantially semi-circular valve cusp base forming portion. 2. The method in accordance with claim 1 ,wherein dipping the new valve cusp comprises dipping the new valve cusp in one of a left coronary cusp dipping portion, right coronary cusp dipping portion and a noncoronary cusp dipping portion of a vessel,the left coronary cusp dipping portion comprising an identification tag of the left coronary cusp dipping portion;the right coronary cusp dipping portion comprising an identification tag of the right coronary cusp dipping portion; andthe noncoronary cusp dipping portion comprising an identification tag of the noncoronary cusp dipping portion.3. The method in accordance with claim 1 ,wherein obtaining the new valve cusp comprises obtaining the new valve cusp by:lining for a cusp shape by drawing along an inner peripheral surface of a scribing portion of a template which relates to the nominal diameter to the pericardium,the inner peripheral surface of the scribing portion comprising:an inner peripheral surface of a valve cusp base forming portion of the template which has a diameter as a sum of a diameter defined as the nominal diameter and an allowance for stitching margins; andan inner peripheral surface of a coaptation zone forming portion in ...

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Номер записи: 76
06-03-2014 дата публикации

Heart Valve Sealing Devices

Номер: US20140067048A1
Автор: Chau Mark, Delgado Sergio, Oba Travis, Taft Robert C.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet. 1. A prosthetic device for treating heart valve regurgitation comprising:a radially compressible and radially expandable body having a first end, a second end, and an outer surface extending from the first end to the second end; andan anchor having a connection portion and a leaflet capture portion, wherein:the connection portion is coupled to the body such that the leaflet capture portion is biased against the outer surface of the body when the body is in a radially expanded state;the prosthetic device is configured to capture a leaflet of a native heart valve between the leaflet capture portion of the anchor and the outer surface of the body; andthe body is configured to prevent blood from flowing through the body in a direction extending from the first end to the second end and in a direction extending from the second end to the first end.2. The device of claim 1 , wherein:the outer surface of the body comprises a first side against which the anchor is biased and a second side opposite the first side; andthe connection portion of the anchor is coupled to the body on the second side of the body.3. The device of claim 2 , wherein:the anchor comprises an elongated member that is coupled to the second side of the body at a connection location; andthe elongated member comprises a ventricular portion that extends from the connection location across the first end of the body.4. The device of claim 3 , wherein the ventricular portion comprises first and ...

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Номер записи: 77
06-03-2014 дата публикации

Heart Valve Sealing Devices

Номер: US20140067054A1
Автор: Chau Mark, Cooper Alexander H., Delgado Sergio, Oba Travis, Rowe Stanton J., Taft Robert C.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet. 1. A prosthetic device for treating heart valve regurgitation comprising:a main body portion having a connection portion and a free end portion, wherein:the connection portion is configured to be coupled to a first one of the two native mitral valve leaflets such that the device is implanted within a native mitral valve orifice; andwhen the device is implanted within the native mitral valve orifice, the free end portion moves laterally toward a second one of the two native mitral valve leaflets during systole, thereby helping to seal the orifice and reduce mitral regurgitation during systole, and the free end portion moves laterally away from the second native mitral valve leaflet during diastole to allow blood to flow from the left atrium to the left ventricle during diastole.2. The device of claim 1 , wherein the connection portion of the main body is thicker than the free end portion.3. The device of claim 1 , wherein the main body portion further comprises an atrial portion that contacts the native mitral valve annulus within the left atrium adjacent to the first native mitral valve leaflet.4. The device of claim 1 , further comprising a ventricular anchor that clips around a lower end of the first native mitral valve leaflet claim 1 , thereby securing the device to the first native mitral valve leaflet.5. The device of claim 4 , wherein the anchor comprises a paddle shape with a broad upper end portion and a relatively narrow neck portion ...

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Номер записи: 78
20-03-2014 дата публикации

METHOD FOR ALTERING THE GEOMETRY OF THE HEART

Номер: US20140081393A1
Автор: Hasenkam John M., Nielsen Sten L., Smerup Morten
Принадлежит: Edwards Lifesciences AG

A system () for altering the geometry of a heart (), comprising an annuloplasty ring; a set of elongate annulus-papillary tension members (), adapted for forming a link between said ring () and a papillary muscle, and a first set of papillary anchors () for connecting each of the tension members () to the papillary muscle; and where said annuloplasty ring () has at least one aperture (); where each of said annulus-papillary tension members () are extendable through said ring () through said apertures (), and through an atrium to an exterior side of said atrium, such that the distance of each link between the annulus and the muscles is adjustable from a position exterior to the heart while the heart is beating. 1. A method for adjusting , from outside the heart and while the heart is beating , the distance between a native heart valve annulus and associated papillary muscles located within the adjacent ventricle , comprising:inserting a system for altering the geometry of a heart into an atrium of the heart, the system comprising a substantially rigid annuloplasty ring having an upper side and a lower side, an upper aperture located on the upper side and a lower aperture located on the lower side and spaced from the upper aperture around the annuloplasty ring, the annuloplasty ring further including a channel that extends between the upper aperture and the lower aperture, the system further including a flexible, elongate annulus-papillary tension member that extends from a second end through the lower aperture in the annuloplasty ring, through the channel, and through the upper aperture to a first end;passing the second end of the tension member into the ventricle associated with the atrium;attaching the second end of the tension member to a papillary muscle;attaching the annuloplasty ring to the heart valve annulus between the atrium and the associated ventricle;extending the first end of the tension member from the upper aperture of the annuloplasty ring to a ...

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Номер записи: 79
27-03-2014 дата публикации

Tool for the adjustment of a prosthetic anatomical device

Номер: US20140088691A1
Автор: Eric E. Bielefeld
Принадлежит: St Jude Medical LLC

An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment.

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Номер записи: 80
27-03-2014 дата публикации

Two-part prosthetic valve system

Номер: US20140088694A1
Автор: Francesco Maisano, Oded Meiri, Stanton J. Rowe
Принадлежит: Edwards Lifesciences Corp

A prosthetic valve system for replacing a native aortic valve exhibiting regurgitation comprises a support structure and a transcatheter heart valve (THV) that is separate from the support structure. The support structure is radially collapsible and expandable, and deployable on an outflow side of the native aortic valve, circumscribing the native leaflets of the aortic valve. The THV is radially collapsible and expandable, and deployable in an annulus of the native aortic valve to frictionally engage the native leaflets between an interior surface of the support structure and the THY.

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Номер записи: 81
27-03-2014 дата публикации

HEART VALVE ASSEMBLIES

Номер: US20140088697A1
Автор: DREWS Michael J., Fogarty Thomas J., HOLMGREN Neil, Modesitt D. Bruce
Принадлежит: Medtronic, Inc.

A heart valve assembly comprises a first prosthesis configured to expand from an unexpanded state to an expanded state at which the first annular prosthesis contacts native tissue of a body lumen. The heart valve assembly also comprises a second prosthesis comprising a valve, and a connection adapter that secures the second prosthesis to the first prosthesis, the connection adapter having a multi-lobed circumference. 1. A heart valve assembly comprising:a first prosthesis configured to expand from an unexpanded state to an expanded state at which the first annular prosthesis contacts native tissue of a body lumen;a second prosthesis comprising a valve; anda connection adapter that secures the second prosthesis to the first prosthesis, the connection adapter having a multi-lobed circumference.2. The heart valve assembly of claim 1 , wherein the first prosthesis is configured to resiliently expand within the body lumen.3. The heart valve assembly of claim 1 , wherein the first prosthesis comprises an annular ring configured to be folded at the unexpanded state and unfolded at the expanded state.4. The heart valve assembly of claim 1 , wherein the first prosthesis comprises a plurality of fixturing device connectors configured to allow a plurality of fixturing devices to pass.5. The heart valve assembly of claim 4 , wherein the plurality of fixturing devices comprises sutures claim 4 , clips claim 4 , staples claim 4 , or pins.6. The heart valve assembly of claim 1 , wherein:the first prosthesis comprises a first engagement element; andthe connection adapter comprises a second engagement element configured to couple to the first engagement element such that the connection adapter is secured to the first prosthesis.7. The heart valve assembly of claim 6 , wherein:the first engagement element comprises a lip; andthe second engagement element comprises a spring lock tab.8. The heart valve assembly of claim 1 , wherein the second prosthesis further comprises a frame having ...

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Номер записи: 82
03-04-2014 дата публикации

Tissue anchors, systems and methods, and devices

Номер: US20140094906A1
Автор: Aaron M. Call, Donald S. Baim, Edward I. McNamara, Hiroatsu Sugimoto, Jason H. Robinson, Joseph P. Lane, Kate E. Traynor, Mark Maguire, Paul A. Spence, Steven D. Cahalane
Принадлежит: Mitralign Inc

Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

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Номер записи: 83
06-01-2022 дата публикации

ROTATION-BASED ANCHORING OF AN IMPLANT

Номер: US20220000612A1
Автор: HACOHEN Gil
Принадлежит: CARDIOVALVE LTD.

Apparatus is provided for use at a native atrioventricular valve of a heart of a subject. A prosthetic valve structure includes prosthetic leaflets configured to facilitate upstream-to-downstream bloodflow longitudinally through the prosthetic valve structure. The apparatus includes an annular portion configured to be positioned at the native atrioventricular valve and curved anchors that point in a circumferential direction around the annular portion. The anchors each having a leading tip configured to gather chordae tendineae of the heart between the anchors and the annular portion. Rotation of the prosthetic valve structure in the circumferential direction causes the anchors to gather the chordae tendineae between the anchors and the annular portion by the anchors moving, leading tip first, in the circumferential direction. Other embodiments are also described. 117-. (canceled)18. Apparatus for use at a native atrioventricular valve of a heart of a subject , the apparatus comprising a prosthetic valve structure that comprises:prosthetic leaflets configured to facilitate upstream-to-downstream bloodflow longitudinally through the prosthetic valve structure;an annular portion configured to be positioned at the native atrioventricular valve; andcurved anchors that point in a circumferential direction around the annular portion, the anchors each having a leading tip and being configured to gather chordae tendineae of the heart between the anchors and the annular portion upon rotation of the prosthetic valve structure in the circumferential direction in a manner that causes the anchors to gather the chordae tendineae between the anchors and the annular portion by the anchors moving, leading tip first, in the circumferential direction.19. The apparatus according to claim 18 , wherein the anchors are disposed circumferentially around the annular portion.20. The apparatus according to claim 18 , wherein each of the anchors defines a base portion coupled to the annular ...

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Номер записи: 84
06-01-2022 дата публикации

CARDIAC VALVE COMMISSURE BRACE

Номер: US20220000620A1
Автор: Entis Allan C., Keren Gad
Принадлежит:

A brace for mounting to an annulus of a cardiac valve, the brace comprising: first and second bottom gripping wings for gripping the annulus; first and second top gripping wings for gripping the annulus; and a support bridge that connects the top wings to the bottom wings; wherein the brace is formed from a shape memory alloy and is deformable from a delivery configuration to a deployed configuration and in the delivery configuration the top wings are oriented substantially back to back along an axis and the bottom wings are oriented substantially back to back along the same axis, and in the deployed configuration the first top and first bottom gripping wings face each other to grip the annulus between them and the second top and second bottom gripping wings face each other to grip the annulus between them. 1. A brace for mounting to an annulus of a cardiac valve , the brace comprising:first and second bottom gripping wings for gripping the annulus;first and second top gripping wings for gripping the annulus; anda support bridge that connects the top wings to the bottom wings;wherein the brace is formed from a shape memory alloy and is deformable from a delivery configuration to a deployed configuration and in the delivery configuration the top wings are oriented substantially back to back along an axis and the bottom wings are oriented substantially back to back along the same axis, and in the deployed configuration the first top and first bottom gripping wings face each other to grip the annulus between them and the second top and second bottom gripping wings face each other to grip the annulus between them.2. The brace according to wherein the brace comprises a wireform having first and second wire-loops connected by the support bridge.3. The brace according to wherein the support bridge comprises at least one wire segment.4. The brace according to wherein the first top and first bottom gripping wings are wireform gripping wings comprised in the first wire-loop.5 ...

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Номер записи: 85
05-01-2017 дата публикации

SUTURE-SECURING FOR CARDIAC VALVE REPAIR

Номер: US20170000474A1
Автор: ALFIERI Ottavio, DENTI Paolo, GUIDOTTI Andrea, Maisano Francesco, TOBIS Idan, VANERMEN Hugo
Принадлежит:

Apparatus is provided that includes a casing, shaped to define a cavity, and one or more openings in the casing, in which openings one or more sutures are disposable; and a core, disposed in the cavity, and shaped to define a lumen in which the sutures are disposable. The apparatus has an unlocked configuration in which the sutures are disposable within and slidable through the openings and the lumen, and a locking configuration in which the sutures are inhibited from sliding through the openings and the lumen. The apparatus is movable from the unlocked configuration to the locking configuration, and is configured such that, when the sutures are disposed within the openings and the lumen, and the apparatus moves from the unlocked configuration to the locking configuration, the apparatus cuts the sutures at a cutting site, and becomes coupled to the sutures at a coupling site. 174-. (canceled)75. Apparatus for use with one or more sutures , the apparatus comprising:a casing, shaped to define a cavity, and one or more openings in the casing, in which openings the sutures are disposable; anda core, disposed in the cavity, and shaped to define a lumen in which the sutures are disposable, having an unlocked configuration in which the sutures are disposable within and slidable through the openings and the lumen, and a locking configuration in which the sutures are inhibited from sliding through the openings and the lumen,', 'being movable from the unlocked configuration to the locking configuration, and', 'being configured such that, when the sutures are disposed within the openings and the lumen, and the apparatus moves from the unlocked configuration to the locking configuration, the apparatus (1) cuts the sutures at a cutting site of the apparatus, and (2) becomes coupled to the sutures at a coupling site of the apparatus., 'the apparatus76. The apparatus according to claim 75 , wherein:the casing defines two or more openings, the openings being provided along a ...

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Номер записи: 86
07-01-2021 дата публикации

PERCUTANEOUS TRANSCATHETER REPAIR OF HEART VALVES VIA TRANS-APICAL ACCESS

Номер: US20210000601A1
Автор: Buchbinder Maurice, Shaolian Samuel M.
Принадлежит: Valcare, Inc.

Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves via a trans-apical approach to accessing the heart. A guiding sheath may be introduced into a ventricle of the heart through an access site at an apex of the heart. A distal end of the guiding sheath can be positioned retrograde through the target valve. An annuloplasty ring arranged in a compressed delivery geometry is advanced through the guiding sheath and into a distal portion of the guiding sheath positioned within the atrium of the heart. The distal end of the guiding sheath is retracted, thereby exposing the annuloplasty ring. The annuloplasty ring may be expanded from the delivery geometry to an operable geometry. Anchors on the annuloplasty ring may be deployed to press into and engage tissue of the annulus of the target valve. 1. A system for percutaneous transcatheter delivery of an annuloplasty ring to repair a target valve of a heart via a trans-apical approach , the delivery apparatus comprising:a guide sheath having a lumen therethrough and configured to be positioned into the heart via an access site through a wall of the heart at the apex of the heart, the guide sheath having a length configured to be positioned through a ventricle of the heart, retrograde through the target valve, and into an atrium of the heart;a delivery assembly configured to be positioned within the guide sheath and advanced to a distal portion of the guide sheath; andthe annuloplasty ring configured to be arranged in a compressed delivery geometry within a plane that is transverse to a longitudinal axis of the lumen of the guiding sheath, wherein the annuloplasty ring comprises a plurality of anchors configured to be pressed into and engage tissue of an annulus of the target valve.2. The system of claim 1 , wherein the delivery assembly comprises a balloon assembly comprising:an upper balloon portion defining an ...

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Номер записи: 87
02-01-2020 дата публикации

PROSTHETIC HEART VALVE WITH UPPER SKIRT

Номер: US20200000580A1
Автор: HACOHEN Gil
Принадлежит:

Apparatus for use at a native atrioventricular valve of a heart of a subject includes a prosthetic valve structure. The prosthetic valve structure comprises a valve ring, a leaflet frame, a plurality of prosthetic leaflets, and an upper skirt. The valve ring circumscribes a longitudinal axis of the prosthetic valve structure. The leaflet frame is disposed within the valve ring. The prosthetic leaflets are coupled to the leaflet frame, and are configured to facilitate upstream-to-downstream bloodflow longitudinally through the prosthetic valve structure. The upper skirt includes an annular skirt fabric, and an annular skirt frame coupled to the valve ring by the skirt fabric. The upper skirt extends radially outward and in an upstream direction from the valve ring. The upper skirt is configured to rest against an atrial portion of the native atrioventricular valve. Other embodiments are also described. 117-. (canceled)18. Apparatus for use at a native atrioventricular valve of a heart of a subject , the apparatus comprising a prosthetic valve structure that comprises:a valve ring that circumscribes a longitudinal axis of the prosthetic valve structure;a leaflet frame, disposed within the valve ring;a plurality of prosthetic leaflets, coupled to the leaflet frame, and configured to facilitate upstream-to-downstream bloodflow longitudinally through the prosthetic valve structure; and [ an annular skirt fabric; and', 'an annular skirt frame coupled to the valve ring by the skirt fabric,, '(i) comprising, '(ii) extending, radially outward and in an upstream direction, from the valve ring, and', '(iii) configured to rest against an atrial portion of the native atrioventricular valve., 'an upper skirt,'}19. The apparatus according to claim 18 , wherein an upstream portion of the leaflet frame is disposed within the valve ring.20. The apparatus according to claim 19 , wherein an upstream end of the leaflet frame is disposed within the valve ring.21. The apparatus according ...

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Номер записи: 88
02-01-2020 дата публикации

Truncated Cone Heart Valve Stent

Номер: US20200000583A1
Автор: Lozonschi Lucian, Lutter Georg
Принадлежит:

A heart valve stent having a section with a heart valve implant and several proximally disposed tissue anchors, also comprising a plurality of anchoring threats, each with a proximate end fastened to the stent or valve and a distal end attached to tissue within a heart chamber to provide tension between the heart chamber tissue and the stent. 1. (canceled)2. A prosthetic mitral valve comprising:a self-expanding stent having a proximal atrial section and a distal body section;a prosthetic valve assembly disposed within the body section of the stent; anda cloth member positioned on an exterior surface of the atrial section of the stent;wherein the atrial section of the stent includes a first tissue anchor connected to, and flaring radially outward from, a first end of the body section, the first tissue anchor including a plurality of circumferentially arranged expandable stent cells adapted to anchor to a first tissue area on an atrial side of a native mitral valve annulus; andwherein the body section of the stent includes a plurality of second tissue anchors extending therefrom adapted to anchor to a second tissue area disposed distally to the first tissue area.3. The prosthetic mitral valve of claim 2 , wherein the prosthetic valve assembly is directly coupled to the body section of the stent.4. The prosthetic mitral valve of claim 2 , wherein the cloth member is formed of a material selected from the group consisting of synthetics claim 2 , pericardium claim 2 , and polytetrafluoroethylene.5. The prosthetic mitral valve of claim 2 , wherein the cloth member is also positioned on an exterior surface of the body section of the stent.6. The prosthetic mitral valve of claim 2 , wherein the plurality of second tissue anchors includes a plurality of anchoring sutures.7. The prosthetic mitral valve of claim 2 , wherein the body section of the stent has a shape of a truncated cone.8. The prosthetic mitral valve of claim 2 , wherein one side of the body section is flattened ...

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Номер записи: 89
02-01-2020 дата публикации

SYSTEM AND METHOD FOR IMPLANTING AND SECURING A BIOPROSTHETIC DEVICE TO WET TISSUE

Номер: US20200000586A1
Автор: Campbell Louis A., Claessens Steven M., Martinez Carolyn Sue, Rodriguez Rodolfo, Tian Bin
Принадлежит:

Systems, devices, kits, and methods are described for securing a bioprosthetic heart valve within an anatomical feature of a patient. Kits can comprise a bioprosthetic heart valve, a curable composition, and an applicator configured to deliver the curable composition to a target area. The bioprosthetic heart valve can comprise a support structure and one or more valve leaflets coupled thereto. The support structure can comprise a sewing portion peripheral of the bioprosthetic heart valve. The support structure and the valve leaflets can define a central flow orifice. The curable composition can comprise a pre-polymer composition and an initiator. Methods can comprise positioning the bioprosthetic heart valve within the anatomical feature of a patient, applying the curable composition to one or both of the bioprosthetic heart valve and the anatomical feature, and curing the curable composition for a cure time. The applying can be performed before or after the positioning. 1. A method for implanting an implant device to an anatomical feature of a patient , the method comprising:positioning the implant device at an implant location inside the patient's body;applying a curable composition to one or both of the implant device and an anatomical feature, the curable composition comprising a pre-polymer composition and an initiator; andcuring the curable composition for a cure time after the applying step;wherein the applying step is performed either before or after the positioning.2. The method of claim 1 , wherein the implant device is selected from the group consisting of: a bioprosthetic heart valve and an annuloplasty ring.3. The method of claim 1 , wherein the implant device is a bioprosthetic heart valve and wherein the heart valve comprises a support structure and one or more valve leaflets coupled to the support structure and wherein the support structure defines a central flow orifice.4. The method of claim 3 , wherein the bioprosthetic heart valve further ...

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Номер записи: 90
02-01-2020 дата публикации

MITRAL VALVE ANNULOPLASTY DEVICE WITH TWISTED ANCHOR

Номер: US20200000591A1
Автор: NIEMINEN Gregory D., Thaler Carly A.
Принадлежит:

The present invention relates to a tissue shaping device adapted to be disposed in a vessel near a patient's heart to reshape the patient's heart. The device comprises a first anchor and a second anchor adapted to be deployed by a catheter to engage a vessel wall while the first anchor is adapted to resist the compression of a first part of the first anchor and resist the expansion of a second part of the first anchor in response to a compressive force on the first part. 1. A mitral valve therapy device , the therapy device comprising:an expandable first anchor, an expandable second anchor, and a connecting member extending therebetween, a distal end, a proximal end, and an axis that extends between the distal and proximal ends and along the connecting member,the expandable first anchor having an anchored configuration in which a first anchor apex is in an anchor portion that is spaced radially furthest away from the axis,the expandable first anchor comprising a first segment and a second segment, and in the anchored configuration the first segment engages the second segment to form at least one full twist around the second segment in the apex of the expandable first anchor in which the first segment passes over the second segment and then under the second segment and then over the second segment, and in which the second segment passes under the first segment and then over the first segment and then under the first segment,the expandable first anchor further comprising a securing member for securing an end of the first segment and an end of the second segment therein at a distal end of the securing member, the securing member generally aligned with the connecting member,the first segment extending distally from the securing member, below the axis and away from the apex, and forming a first strain relief portion, the second segment extending distally from the securing member, below the axis and away from the apex, and forming a second strain relief portion,wherein ...

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Номер записи: 91
04-01-2018 дата публикации

METHOD FOR REPLACING A HEART VALVE

Номер: US20180000585A1
Автор: Solem Jan Otto
Принадлежит:

A method for replacing a native heart valve in need thereof comprises delivering to the native heart valve an apparatus comprising a valve member, a connecting member, and an anchor member suitable for anchoring the apparatus. The valve member reversibly moves between an open position and a closed position to augment or replace the function of the native valve leaflets, thereby reducing valve regurgitation. Some embodiments include a stent that is positioned in the native heart valve with the valve member disposed therein. 1. A method for replacing a function of a native heart valve , the method comprising:compressing a valve-replacement apparatus to a small diameter;delivering the valve-replacement apparatus to a native mitral valve using a catheter;expanding a stent of the valve-replacement apparatus within the native mitral valve, the stent at least partially covered, a valve member disposed within the stent, the valve member including a plurality of pericardial tissue flaps arranged side-by-side with adjacent surfaces having coaptation areas in close contact with each other to prevent leakage between the flaps;extending a portion of a first end of a flexible connecting member through a tissue wall, a second end of the connecting member coupled to an outflow portion of the valve-replacement apparatus; andsecuring a disk-shaped element to the connecting member, the disk-shaped element contacting the tissue wall, to fix a position of the valve member within the native mitral valve.2. The method of claim 1 , wherein extending the portion of the first end of a flexible connecting member through the tissue wall includes extending the portion of the first end of a flexible connecting member through an interventricular muscular septum or a muscular ventricular wall.3. The method of claim 1 , wherein the disk-shaped element is a first disk-shaped element claim 1 , the method further comprising securing a second disk-shaped element to the connecting member claim 1 , the ...

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Номер записи: 92
04-01-2018 дата публикации

SYSTEMS AND METHODS FOR HEART VALVE THERAPY

Номер: US20180000586A1
Автор: Forsberg Andrew T., Ganesan Kavitha, JR. Cyril J., Krone Douglas J., Martz Erik O., Mortier Todd J., Schweich, Venkatasubramanian Ramji T.
Принадлежит:

Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks. This document also describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. In addition, this document describes prosthetic heart valve designs and techniques that reduce the risk of interference between the prosthetic valves and chordae tendineae. 1. A prosthetic mitral valve system comprising: a frame member defining an outer profile and an interior frame member space; and', 'an occluder disposed within the interior frame member space, the occluder having an open configuration and a closed configuration,, 'a valve assembly comprisingwherein the frame member comprises a proximal end frame portion and a distal end frame portion, wherein an outer periphery of the distal end frame portion comprises a generally flat region and a generally round region, and wherein at least some portions of the generally flat region extend distally toward the interior frame member space.2. The prosthetic mitral valve of claim 1 , further comprising an anchor assembly defining an interior anchor assembly space claim 1 , wherein the valve assembly is selectively mate-able with the interior anchor assembly space.3. The prosthetic mitral valve of claim 2 , wherein the anchor assembly comprises an expandable anchor frame including a hub and a sub-annular support arm extending from the hub claim 2 , wherein the sub-annular support arm extends to an anchor foot having a surface configured for engagement with a sub-annular gutter of a native mitral valve.4. The prosthetic mitral valve of claim 3 , wherein a distance measured ...

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Номер записи: 93
04-01-2018 дата публикации

Methods, Devices and Systems for Treating Venous Insufficiency

Номер: US20180000588A1
Автор: Busold Rany Huynh, Perkins D.H., Rafiee Nasser, Thompson Dustin
Принадлежит:

Methods and systems for improving the competency of a venous valve wherein one or more compressor(s) (e.g., space occupying material(s) or implantable device(s)) is/are delivered to one or more location(s) adjacent to a venous valve to compress the venous valve in a manner that causes one or both leaflets of the valve to move toward the other, thereby improving closure or coaptation of the valve leaflets. The compressor(s) may be delivered by an open surgical approach, by a direct percutaneous approach or by a transluminal catheter-based approach. 1. (canceled)2: A method for improving function of a venous valve that comprises valve leaflets , the venous valve being located in a vein that has a wall and a lumen , the method comprising the steps of:positioning, within the lumen of the vein in which the venous valve is located or within the lumen of another blood vessel that has a wall and is located near the venous valve, a tissue penetrating catheter that has a penetrator that is advanceable from the catheter;advancing the penetrator from the tissue penetrating catheter through the wall of the vein or other blood vessel in which the catheter is positioned toward a first location outside of the vein;delivering a first compressor through the penetrator to the first location;retracting the penetrator;repositioning the tissue penetrating catheter;advancing the penetrator from the tissue penetrating catheter through the wall of the vein or other blood vessel in which the catheter is positioned toward a second location outside of the vein, wherein the second location is on an opposite side of the venous valve relative to the first location;delivering a second compressor through the penetrator to the second location;retracting the penetrator; andremoving the tissue penetrating catheter, wherein the first and second compressors at the first and second locations cause sufficient inward compression of the wall of the vein in the area of the venous valve to improve closure of ...

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Номер записи: 94
03-01-2019 дата публикации

Heart valve sealing devices and delivery devices therefor

Номер: US20190000613A1
Автор: Alexander J. Siegel, Asher L. Metchik, David M. Taylor, Devin H. Marr, Eric Robert Dixon, Grant Matthew Stearns, II Gregory Scott Tyler, Lauren R. Freschauf, Matthew T. Winston, Sam Sok, Sergio Delgado, Sirous Darabian, Tam Van Nguyen
Принадлежит: Edwards Lifesciences Corp

An exemplary implantable prosthetic device has a paddle frame, an inner paddle, and an outer paddle. The outer paddle is connected to the inner paddle. The inner and outer paddles are connected to the paddle frame at a connection between the inner paddle and the outer paddle. The paddle frame can be positioned inside the inner paddle, outside the outer paddle, or between the inner and outer paddles.

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Номер записи: 95
03-01-2019 дата публикации

PROSTHETIC HEART VALVE DEVICES AND ASSOCIATED SYSTEMS AND METHODS

Номер: US20190000614A1
Автор: GIFFORD Hanson, Morriss John
Принадлежит:

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve. The device can also include a plurality of asymmetrically arranged arms coupled to the expandable support and configured to receive the leaflets of the native valve between the arms and the outer surface. In some embodiments, the arms can include tip portions for engaging a subannular surface of the native valve. 130-. (canceled)31. A prosthetic heart valve device for treating a native mitral valve having a native annulus and native leaflets , comprising:a valve member configured to allow blood flow in a downstream direction toward a ventricle and at least partially blocking blood flow in an upstream direction toward an atrium;a support carrying the valve member;an anchoring portion coupled to and at least partially extending around the support, the anchoring member having a downstream end and an upstream end, wherein the anchoring portion extends outwardly from the downstream end in an upstream direction such that the anchoring portion has a greater diameter at the upstream end than at the downstream end, wherein the anchoring portion is configured to exert force against an inner surface of the native leaflets when the prosthetic heart valve device is in an expanded configuration at the native annulus; anda skirt on the anchoring portion and flaring outwardly in the upstream direction such that an upstream region of the skirt is spaced outwardly from the support, wherein the skirt extends around the entire circumference of the anchoring portion.32. The prosthetic heart valve device of wherein the anchoring portion comprises a plurality of elongated members.33. The prosthetic heart valve device ...

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Номер записи: 96
03-01-2019 дата публикации

HEART VALVE ASSEMBLY SYSTEMS AND METHODS

Номер: US20190000618A1
Автор: JR. Cyril J., Mortier Todd J., Schweich
Принадлежит:

Heart valve assembly systems and methods configured for medical interventional procedures. In one aspect, the methods and systems involve a modular approach to treatment. 1an anchor, the anchor including structure residing above and below a valve annulus and an interior; anda valve assembly defining structure configured to be implanted separately from the anchor and having an exterior sized and shaped to lockingly and directly engage the interior of the anchor.. A heart valve assembly system for implantation at an interventional site, comprising: This document is a continuation of U.S. application Ser. No. 15/378,737 filed Dec. 14, 2016, which is a continuation of U.S. application Ser. No. 14/677,665 filed on Apr. 2, 2015, which is a continuation of U.S. application Ser. No. 13/842,490 filed on Mar. 15, 2013, which claims the benefit of: U.S. Provisional Application Ser. No. 61/635,741 filed on Apr. 19, 2012, and U.S. Provisional Application Ser. No. 61/669,383 filed on Jul. 9, 2012, the entire disclosures of these previous applications being expressly incorporated herein.The present disclosure relates to medical interventional systems and methods and more particularly, to artificial valve assembly systems and methods. The long-term clinical effect of valve regurgitation is well recognized as a significant contributor to cardiovascular related morbidity and mortality. In particular, there are two basic classifications of mitral regurgitation (“MR”), primary and secondary. Primary MR results when there is either direct tissue pathology of the valve structures or there is structural damage/alteration of one or more valve structures (leaflets, chordae). Secondary MR is a functional loss of valve competence caused left ventricular dilatation, and secondary alteration of mitral valve geometry following damage to the myocardium and left ventricle (“LV”) causing. Whether valvular in origin leading to a ventricular problem or of ventricular/muscle origin leading to the ...

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Номер записи: 97
03-01-2019 дата публикации

ADJUSTABLE IMPLANT SYSTEM

Номер: US20190000620A1
Автор: Anderson Daniel, Pool Scott, Shaolian Samuel, Tsukashima Ross
Принадлежит:

Systems and methods treat a heart valve using a magnetically adjustable annuloplasty ring attached to or near a cardiac valve annulus. A changing magnetic field may be used to selectively increase or decrease a circumference of, or otherwise modify the shape of, the implanted annuloplasty ring. The adjustable annuloplasty ring includes a tubular body member, one or more adjustable members, and an internal magnet within the tubular body member. The tubular body member and the one or more adjustable members form a ring shape. The internal magnet is configured to rotate in response to a rotating external magnetic field. The internal magnet is coupled to the one or more adjustable members to change a dimension of the ring shape as the internal magnet rotates. A system for treating a heart valve may include an external adjustment device having one or more external magnets to generate the rotating external magnetic field. 120.-. (canceled)21. A system for changing the dimension of a portion of a subject , the system comprising: a tubular body member;', 'an internal magnet disposed within the tubular body member, the internal magnet configured to rotate in response to a rotating external magnetic field originating external to the subject;', 'an adjustable member operatively coupled to the internal magnet, wherein the internal magnet is configured to rotate in response to the moving magnetic field and change a dimension of the adjustable implant as the internal magnet rotates;', 'wherein the tubular body member and the adjustable member substantially form an annulus and are configured to be placed around at least the portion of the subject., 'an adjustable implant configured for implantation within a patient comprising22. The system of claim 21 , wherein the adjustable member comprises one or more adjustable members.23. The system of claim 21 , wherein the internal magnet comprises a cylindrical magnet.24. The system of claim 23 , further comprising a magnetic brake ...

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Номер записи: 98
03-01-2019 дата публикации

Force transducting inflatable implant system including a dual force annular transduction implant

Номер: US20190000621A1
Автор: Christopher Seguin, John Wilson
Принадлежит: Harmony Development Group Inc

An implant system for restoring and improving physiological intracardiac vortical flow in a human heart is provided including a dual force transducting annular implant comprising laterally extending struts transitioning into annular structural members for positioning on the atrial side of the valve annulus; an anchoring system comprising a therapeutic base plate assembly attachable to the apex of the heart; and a tether assembly comprising a tether connected between the implant and the therapeutic base plate assembly.

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Номер записи: 99
03-01-2019 дата публикации

HEART VALVE REPAIR DEVICES FOR PLACEMENT IN VENTRICLE AND DELIVERY SYSTEMS FOR IMPLANTING HEART VALVE REPAIR DEVICES

Номер: US20190000622A1
Автор: BEN-ZVI Yonatan, YARON Ira
Принадлежит: MITRALIX LTD.

Devices and methods for the repair of the functioning of heart valves are provided. A device may comprise a ventricular winding having a generally spiral shape, wherein the device is free of any atrial stabilizing section. A method involves positioning the device such that chords associated with the heart valve are positioned within the path of the generally spiral shape of the ventricular winding and turning the ventricular winding such that the chords move closer to the center of the ventricular winding. The ventricular winding draws the chords closer together, thereby pulling the valve leaflets closer together in order to facilitate their coaptation and proper closing. A delivery system for maneuvering and releasing a heart valve repair device comprises an applicator tube and internal rod. 1. A device for assisting the functioning of a heart valve comprising:a ventricular winding having a generally spiral shape adapted to be positioned on a ventricular side of the heart valve such that chords associated with the heart valve are positioned within the path of the generally spiral shape of the ventricular winding;wherein the device is free of any atrial stabilizing section.2. A device as in claim 1 , wherein the ventricular winding is substantially flat.3. A device as in claim 1 , wherein the ventricular winding is substantially conical.4. A device as in claim 1 , wherein the generally spiral shape of the ventricular winding is substantially circular.5. A device as in claim 1 , wherein the generally spiral shape of the ventricular winding is substantially elliptical.6. A device as in claim 1 , wherein the device claim 1 , including the ventricular winding claim 1 , comprises a wire claim 1 , bundle of wires claim 1 , strip claim 1 , rod claim 1 , tube claim 1 , or a combination thereof.7. A device as in claim 1 , wherein the device is comprised at least in part of a metallic material.8. A device as in claim 1 , wherein the device is comprised at least in part of a ...

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Номер записи: 100