УСТРОЙСТВО ДЛЯ ПРОДВИЖЕНИЯ СТЕНТОВ

Изобретение относится к медицинской технике, а именно к устройствам для размещения стентов, например, в сосуде или протоке тела или в структуре, используемой для тестирования или демонстрирования (такой как полимерная трубка). Устройство для продвижения стента содержит наружный футляр и стент-зацепляющий элемент, расположенный внутри наружного футляра. Стент-зацепляющий элемент выполнен с возможностью перемещения стента в дистальном направлении из наружного футляра на протяжении по меньшей мере двух периодов зацепления стента стент-зацепляющим элементом. Каждый период зацепления выполнен с возможностью перемещения стента в дистальном направлении без механического сопутствующего возврата наружного футляра. Каждый период зацепления отделен периодом без зацепления стента стент-зацепляющим элементом, в котором стент не приводится в движение в дистальном направлении. 20 з.п. ф-лы, 16 ил.

ВНУТРИПРОСВЕТНЫЙ СОСУДИСТЫЙ ПРОТЕЗ

Изобретение относится к медицине, а именно к сердечно-сосудистой хирургии. Изобретение обеспечивает протезирование для перекрытия абдоминальной аортальной аневризмы. Протез содержит трубчатый проволочный каркас с проксимальным и дистальным концом и проходящий через протез центральный просвет. Каркас содержит, по меньшей мере, первый и второй смежные в осевом направлении трубчатые сегменты. Каждый трубчатый сегмент содержит последовательность проксимальных и дистальных изгибов. Трубчатые сегменты соединены проходящим между ними соединителем. Первый и второй сегменты и соединитель выполнены из одного куска проволоки. По меньшей мере, первый дистальный изгиб в первом трубчатом сегменте соединен, по меньшей мере, с первым проксимальным изгибом во втором трубчатом сегменте. По меньшей мере, первый проксимальный изгиб и первый дистальный изгиб содержат на себе петлю. Изобретение также касается способа изготовления внутрипросветного протеза, многозонного внутрипросветного протеза и способа имплантации ...

СИСТЕМА И СПОСОБ ЭНДОЛЮМИНАЛЬНОГО ПРОТЕЗИРОВАНИЯ РАЗВЕТВЛЯЮЩИХСЯ СОСУДОВ И СОСУДОВ С ОТВЕТВЛЕНИЯМИ

Группа изобретений относится к хирургии и может быть применима для эндолюминального протезирования основного анатомического канала в теле пациента в области, в которой по меньшей мере один ответвляющийся анатомический канал отходит от основного анатомического канала. Система включает эндоаортальный имплантат и имплантат ответвления. Эндоаортальный имплантат содержит первую гибкую трубку, имеющую по меньшей мере один проем ответвления, гибкое магнитное кольцо, размещенное вокруг по меньшей мере одного проема ответвления, устройство фиксации для поддержания первой трубки в практически фиксированном положении внутри основного анатомического канала так, чтобы проем ответвления совмещался с ответвляющимся анатомическим каналом. Имплантат ответвления содержит вторую гибкую трубку, соединительное устройство, выборочно приводимое в действие для соединения проксимального конца второй трубки с проемом ответвления первой трубки после приведения его в действие для обеспечения протекания текучей среды ...

УСТРОЙСТВО ДЛЯ ПРОДВИЖЕНИЯ СТЕНТОВ

... 1. Устройство, содержащее:наружный футляр; истент-зацепляющий элемент, расположенный внутри наружного футляра;в котором стент выполнен с возможностью перемещения в дистальном направлении из наружного футляра на протяжении, по меньшей мере, двух периодов зацепления стента стент-зацепляющим элементом, при этом каждый период зацепления выполнен с возможностью приведения стента в перемещение в дистальном направлении без механического сопутствующего возврата наружного футляра, причем каждый период зацепления отделен периодом без зацепления стента стент-зацепляющим элементом, в котором стент не приводится в движение в дистальном направлении.2. Устройство по п.1, дополнительно содержащее стент, расположенный внутри наружного футляра.3. Устройство по п.2, в котором стент имеет дистальный конец, проксимальный конец и полость, простирающуюся между дистальным концом и проксимальным концом, при этом стент-зацепляющий элемент расположен, по меньшей мере, частично внутри полости стента.4. Устройство ...

РАЗВЕТВЛЕННОЕ И В ВЫСОКОЙ СТЕПЕНИ ПРИСПОСАБЛИВАЕМОЕ МЕДИЦИНСКОЕ УСТРОЙСТВО, ВЫПОЛНЕННОЕ С ВХОДОМ ДЛЯ ОТВЕТВЛЕНИЯ

... 1. Многопросветный стент-графт, содержащий основной просвет, образованный графтом, состоящим из самой внутренней трубки с отверстием и самой внешней трубки с отверстием, при этом указанный графт поддерживается с помощью основного стента; и добавочный просвет, расположенный между самой внутренней трубкой и самой внешней трубкой указанного графта; при этом указанный добавочный просвет сообщается по текучей среде через указанные отверстия.2. Стент-графт по п.1, в котором указанный добавочный просвет образован добавочным стентом или стентом в сборе.3. Стент-графт по п.1, в котором самая внешняя трубка выполнена из вспененного политетрафторэтилена.4. Стент-графт по п.1, в котором самая внутренняя трубка выполнена из вспененного политетрафторэтилена.5. Стент-графт по п.1, в котором указанный основной стент прикреплен к указанному графту с помощью соединительного элемента.6. Стент-графт по п.2, в котором указанный основной стент содержит структуру в виде сдвоенного W, которая образует участок ...

СПОСОБЫ ДЛЯ СКРЕПЛЕНИЯ КОНЦОВ НИТЕЙ И ПОЛУЧЕННЫЕ В РЕЗУЛЬТАТЕ УСТРОЙСТВА

... 1. Способ формирования саморасширяющегося стента, содержащий следующие стадии:образование первого изгиба в каждой из множества нитей, каждая из которых включает в себя часть нити на обоих сторонах первого изгиба нити, при этом каждая часть нити имеет конец;сплетание частей нити, при этом каждый конец частей нити расположен вблизи первого конца нити после сплетания частей нити;термообработка множества нитей в течение первого периода времени после сплетания частей нити;образование второго изгиба каждой из множества нитей.2. Способ по п.1, дополнительно содержащий термообработку множества нитей в течение второго периода времени после формирования вторых изгибов нитей.3. Способ по п.1, дополнительно содержащий обратное заплетание некоторых частей нити после формирования вторых изгибов нитей, которое содержит их прохождение, по меньшей мере, двумя пересечениями нити от первого конца стента.4. Способ по п.1, дополнительно содержащий обрезку частей нити.5. Способ по п.1, в котором множество нитей ...

Introducer assembly and dilator tip therefor

Graft with Leg

Apparatus for use in coronary artery bypass surgery

The apparatus comprises a blood flow conduit 10 of T- or L-shape having a first end for insertion into and retention within a wall of a heart chamber 44 containing oxygenated blood and a second end for retention within a coronary artery 30, the conduit defining an open flow blood path during both systole and diastole. The conduit may be such as to bias forward flow of blood from the first towards the second end while not blocking reverse flow and may comprise a deflection surface for blocking flow through the conduit from impinging directly upon the coronary artery. Means may be provided in the conduit for reducing but not blocking blood flow during diastole.

STENTIMPLANTATE WITH WINDOWS

STENT WITH SEGMENTED PROSTHESIS

EQUIPMENT AND PROCEDURE FOR LINES AND MATERIALS

ENDOLUMINAL TRANSPLANT

STENT IMPLANT

DELIVERY CATHETER FOR FORKED TRANSPLANT

DEVICE FOR THE TREATMENT OF THE THORAX AORTA

NEWPOSITION-CASH AND BACKGET-CASH OF VASCULAR ONES STENT/GRAFT

PROSTHESIS FOR THE REPAIR A THORAX ANEURYSM

ENDOLUMINALE SIDE BRANCH PROSTHESIS

STENTSYSTEM

SUPRANIERENPROTHESE AND KIDNEY ARTERIENBYPASS

MEDICAL INSTRUMENT WITH WINDOW

DEVICE FOR BRINGING IN A MEDICAL TRANSPLANT

STENT GRAFT WITH A SCHR�GABZWEIG

MEDICAL TRANSPLANT LINKS

INTRODUCTION TOOL FOR ENDOLUMINALE PROSTHESIS WITH ENDOLUMINALER PROSTHESIS

PROTHETI TRANSPLANT FOR THE AORTABOGEN

Staged deployment of expandable implant

An endoprosthesis delivery system includes an expandable endoprosthesis including a side branch portal, a first primary sleeve releasably constraining a proximal portion of the expandable endoprosthesis to a collapsed configuration, a second primary sleeve in parallel with the first primary sleeve, the second primary sleeve releasably constraining a distal portion of the expandable endoprosthesis to the collapsed configuration, and a secondary sleeve within the first primary sleeve. Upon release of the first primary sleeve, the secondary sleeve releasably constrains the proximal portion of the expandable endoprosthesis to a partially expanded configuration allowing access to the side branch portal via the partially expanded proximal portion of the expandable endoprosthesis.

VASCULAR STENT GRAFTS

Side branched endoluminal prostheses and methods of delivery thereof

Stent-graft having facing side branch portals

In various embodiments, a device for treating disease of a vessel includes a stent graft (100) having an outer surface; and at least two side branch portals (110) each having a proximal ends and a distal end. Each distal end is substantially contiguous with the outer surface of the stent graft. In various other embodiments, the distal ends are generally axially further spaced apart than the proximal ends.

Systems for removal of atherosclerotic plaque or thrombus at a treatment site

A system for removing plaque or thrombus from the vasculature and/or deployed medical devices is described. An embodiment can include a plaque reduction brush comprising at least one support adapted to allow the brush to be endoluminally deliverable via a delivery device to a treatment site; and a plurality of bristles extending from the at least one support and being arranged in a predetermined pattern along the at least one support, each of the plurality of bristles having a length, wherein one or more of the plurality of bristles has a bending portion along the length that is more easily bent than another portion of the length thereof, said bending portion facilitating bending of the one or more of the plurality of bristles between a compressed delivery configuration and an expanded use configuration.

Stent grafts for the thoracic aorta

A method of temporarily reducing the diameter of a stent graft (10) and a stent graft with its diameter reduced. The stent graft has a tubular body and self expanding stents. The method comprising extending a release wire (18, 20) part helically along the graft material tube from substantially one side of the graft material tube at one end (14) of the graft material tube to substantially the opposite side of the graft material tube at the other end (12) of the graft material tube along the stent graft and stitching the release wire into the graft material tube, at each of a number of positions along the release wire looping flexible threads (22, 24) around the release wire and extending the flexible threads laterally around the circumference of the stent graft in each direction to a position away from the release wire, engaging the first flexible threads into the graft material or around struts of the stent, and drawing the ends of the thread together and tying ends of the thread to thereby ...

PROSTHESIS HAVING PIVOTING FENESTRATION

The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, and a second perimeter attached to and surrounding the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape. In one aspect, the prosthesis includes at least three pivotable fenestrations, ...

Customized aortic stent device and method of making the same

The application provides customized aortic stent and stent graft devices and methods for the manufacture thereof. The customized aortic stent or stent graft are patient-specific in that they conform to at least part of the ascending aorta, aortic arch and/or thoracic aorta.

Branched vessel endoluminal device

An endoluminal prosthesis (520) comprises a prosthetic trunk having a trunk lumen and a trunk wall, a first prosthetic branch (533) having a first branch lumen and a branch wall, and a second prosthetic branch (534) having a second branch lumen. The first branch lumen and the second branch lumen are both in fluid communication with the trunk lumen through the trunk wall and the second branch lumen is in fluid communication with the first branch lumen through the branch wall. Additional devices, systems, and methods are disclosed.

Pararenal and thoracic arch stent graft and methods for use

Example stent grafts and methods for placement thereof are provided. An example stent graft may include (a) a main body stent graft defining a lumen that has a first end and second end, (b) a diaphragm coupled to the main body stent graft, where the diaphragm defines at least three openings and (c) at least three stent graft extensions each defining a lumen, where a first end of each of the three stent graft extensions is coupled to one of the three openings.

System and method for endoluminal grafting of bifurcated or branched vessels

Low-profile, non-stented prosthesis for transluminal implantation

A by-pass graft

An implant comprising a support structure and a transition material made of porous plastics material

Medical grafting methods and apparatus

FENESTRATED STENT GRAFTS

A stent graft (1) with at least one fenestration (40) including a peripheral (37) reinforcement around at least part of the fenestration. There can also be a tubular extension (15). The side arm includes a stent (19) and a cover (17) and extends from and is in fluid communication with the fenestration and the stent graft. The stent may be a self expanding stent. The ring and/or tubular extension provides better support and sealing for an extension arm. The fenestratîon (40) can be circular or if towards the ends of the stent graft may be in the form of a U-shape (50) with an open end.

AAA REPAIR DEVICE WITH ANEURYSM SAC ACCESS PORT

An abdominal aortic aneurysm repair device having an access port may be utilized to percutaneously access the aneurismal sac without disturbing the repair. The access port has a self-sealing member for maintaining the port in the normally closed position. The insertion of a percutaneous device into the port opens the port.

SIDE BRANCH STENT GRAFT

... ²²² A joining arrangement between a main tube and a side arm in a side²arm stent graft. The side arm is stitched into an aperture in the main tube ²and ²is in fluid communication with it. The aperture is triangular, elliptical or ²rectangular and the side arm is cut off at an angle to leave an end portion ²having a circumferential length equal to the circumference of the aperture. ²The side arm can also include a connection socket comprising a first resilient ²²ring around the arm at its end, a second resilient ring spaced apart along the ²²arm from the first ring and a zigzag resilient stent between the first and ²second rings. The zigzag resilient stent can be a compression stent. Both ²the main tube and the side arm are formed from seamless tubular ²biocompatible graft material.² ...

MEDICAL APPARATUS AND METHOD OF MAKING THE SAME

The invention relates to a novel medical apparatus for treatment of obesity, diabetes, and/or other obesity-associated health problems. The apparatus is used to impede absorption of nutrients within the gastrointestinal tract, i.e., substantially isolating nutrients from a portion of the gastrointestinal tract. The apparatus can be implanted using minimally invasive techniques, such a transesophageal approach under visualization. More specifically, the apparatus is used to impede absorption of nutrients within the gastrointestinal tract, i.e., substantially isolating nutrients from a portion of the gastrointestinal tract. The apparatus may include a sleeve and at least one anchoring component attached to the sleeve with a releasable component. The sleeve may have different properties along its length or there may be multiple sleeves having different properties.

BRANCHED STENT GRAFT SYSTEM

An endovascular prosthetic system comprises an prosthetic device with a major lumen extending therethrough, a major wall, at least one opening in the major wall; at least one branch extending into the major lumen of the prosthetic device the or each branch having a minor lumen, a minor wall, and a fenestration in the minor wall in communication with the major lumen; and at least one guide wire extending through the fenestration and out of the prosthesis through the opening.

ENDOVASCULAR FENESTRATED STENT-GRAFTING

A stent-graft (20) is provided, which is configured to initially be placed in a delivery shaft (40) in a radially-compressed state, and which comprises a support structure (36) and a covering element (38). The support structure (36) has proximal and distal ends, and is shaped so as to define at least a coupling portion (30), which 5 is configured to transition to a partially-radially-expanded state upon deployment of the stent-graft (20) from the delivery shaft (40), in which state the coupling portion (30) defines a sharp tip (34) at the proximal end of the support structure (36). The covering element (38) is securely attached to and covers at least a portion of the support structure (36). A 10 coupling-end expansion tool (100) is configured to transition the coupling portion (30) from the partially-radially-expanded state to a more-radially-expanded state. Other embodiments are also described.

INTRALUMINAL PROSTHESIS ATTACHMENT AND SYSTEMS

Systems and method implant prostheses in the body. The systems and method provide permanent attachment of the prosthesis in the body. The prosthesis can comprise, e.g., an endovascular graft, which can be deployed without damaging the native blood vessel in either an arterial or a venous system. The endovascular graft can comprise, e.g., a radially expanding vascular stent and/or a stent-graft. The graft can be placed in the vasculature, eg., to exclude or bridge an aneurysm, for example, an abdominal aortic aneurysms. The graft desirably adapts to change in aneurysm morphology and repairs the endovascular aneurysm. The fastening systems (27) and methods can be deployed through the vasculature and manipulated from outside the body, to deliver a fastener (28) to attach the graft to the vessel wall.

MULTIVASCULAR NETWORKS AND FUNCTIONAL INTRAVASCULAR TOPOLOGIES WITHIN BIOCOMPATIBLE HYDROGELS

A device made from a hydrogel matrix is provided. The hydrogel matrix includes a photoabsorber with a void architecture in the matrix, having a first vessel architecture and a second vessel architecture that are each tubular and branching, wherein the first and second vessel architectures are fluidically independent from each other. A pre-polymerization solution for forming the device, and methods of fabricating such devices are described. A method of fabricating a 3D hydrogel construct is provided. The method includes using a computer-implemented process to create a 3D model of the construct based on a tessellation of polyhedra having a number of faces connected by edges and vertices, generate a first vascular component of the model, generate a second vascular component of the model, and combine the first and second vascular components of the model.

MODULAR PROSTHESIS AND METHOD FOR BRANCH VESSELS

ENDOVASCULAR ANEURYSM REPAIR SYSTEM

Method and apparatus for implanting radially expandable prostheses (14) in the body lumens rely on tacking or anchoring of the prostheses with separately introduced fasteners (28). The prostheses may be self-expanding or balloon expandable. After initial placement, a fastener applier system (27) is introduced within the expanded prostheses to deploy a plurality of fasteners at at least one prosthesis end, usually as each end of the prosthesis. The fasteners are usually helical fasteners which are delivered from a helical track in the fastener applier by rotation with a rotator wire. The fasteners will be applied singly, typically in circumferentially spaced-apart patterns about the interior of each end of the prosthesis.

DEVICE AND METHOD FOR TREATING THORACIC AORTA

A prosthesis, introducer device and a method for repair of an aortic aneurysm which is positioned at least partially in the ascending aorta (62). The prosthesis (3) has a proximal end (15) and a distal end (5) and is formed from a biocompatible material, the proximal end is adapted to be surgically fastened adjacent and around the aortic heart valve (60) of a patient and the distal end is adapted to extend into the descending aorta (66). The distal end has a distally extending exposed self-expanding stent (9). The introducer device can be deployed through an incision (75) in the thoracic arch (64) and extend down the descending aorta to place the distal end of the prosthesis first and then removed so that the proximal end of the prosthesis can be sutured in place around the aortic heart valve (60).

ENDOLUMINAL GRAFT WITH A PROSTHETIC VALVE

An endoluminal prosthesis (122) is provided for restricting fluid flow in a lumen. The endoluminal prosthesis has a tubular graft having a flexible body with at least one stent (130) coupled thereto. The endoluminal prosthesis also includes a prosthetic valve (138) coupled to the inside the tubular graft. The prosthetic valve can be made of a synthetic or an organic material, such as an extracellular matrix, and can operate to limit fluid flow in one direction, but allow fluid flow in the other direction.

FLOW RESTRICTING STENT-GRAFT

The presently described stent-graft includes a stent frame forming a cavity and frame wires extending around the stent frame perimeter. The stent frame is formed such that the cavity cross sectional area decreases along a first length of a flow restricting section to a cavity minimum cross sectional area and increases along a second length of the flow restricting section. The first length extends from a cavity proximal cross sectional area to the cavity minimum cross sectional area and the second length extends from the cavity minimum cross sectional area to a cavity distal cross sectional area. When placed within a patient's aorta, the stent-graft may help the treatment of congestive heart failure by increasing blood flow to the kidneys. The provided stent-graft may also be adapted for placement within a patient's urethra to help the treatment of urinary incontinence.

PROSTHESIS FOR REPAIRING A BLOOD VESSEL AND METHOD

A prosthesis for repairing a blood vessel, wherein the prosthesis is inserted intraluminally and fixed in the vessel so as to isolate a diseased section thereof and maintain the flow of blood from the vessel to collateral vessels involved in the diseased section, and the prosthesis comprises a stent support and a flexible fabric liner of woven material comprising a plurality of concentric layers, wherein each of said layers has a very open fabric web which allows the passage of blood flow through the layers during the installation of the prosthesis but which allows the sealing of layers once the prosthesis is installed. A method is also provided for safe installation of the prosthesis.

COVERED STENTS WITH SIDE BRANCH

A system for treating stenosis in a target blood vessel, such as the common carotid artery, comprising a graft portion having a main portion and a branch portion extending therefrom. The branch portion extends from the intermediate portion of the main portion at an angle thereto and is in fluid communication with the main portion. A first stent is associated with the main portion and is expandable from a first configuration to a second configuration to retain the main portion in position within the target vessel. A second stent is associated with the branch portion and is expandable from a first configuration to a second configuration to retain the branch portion in position within a branching vessel. In one embodiment, the branch portion is integral with the main portion. In an alternate embodiment the branch portion is connected to the main portion.

ENDOVASCULAR ANEURYSM REPAIR SYSTEM

Method and apparatus for implanting radially expandable prostheses (14) in the body lumens rely on tacking or anchoring of the prostheses with separately introduced fasteners (28). The prostheses may be self-expanding or balloon expandable. After initial placement, a fastener applier system (27) is introduced within the expanded prostheses to deploy a plurality of fasteners at at least one prosthesis end, usually as each end of the prosthesis. The fasteners are usually helical fasteners which are delivered from a helical track in the fastener applier by rotation with a rotator wire. The fasteners will be applied singly, typically in circumferentially spaced-apart patterns about the interior of each end of the prosthesis.

BIFURCATED/BRANCH VESSEL PROSTHESIS

A stent graft has a tubular wall (1) defining a main lumen with at least one fenestration (15) in the wall. A tube (17) extends from the fenestration into the main lumen and is in fluid communication with the main lumen. An extension leg stent graft can be deployed from a branch vessel into the fenestration to seal into the tube. A flared guide (89) associated with the fenestration can be provided interiorly or exteriorly. There is also disclosed a bifurcated intraluminal prosthesis having a body (1), a first leg (7) and a second leg (17), the first leg extending from the body and the second leg extending into the body.

SYSTEM FOR FIXATION OF ENDOLUMINAL DEVICES

A system and method employs collar stents to implant an endoluminal device, such as a stent-graft, in a lumen. The system comprises at least one collar stent adapted to precondition a portion of the lumen for anchoring an endoluminal device having at least a portion adapted to be deployed radially within the collar stent. The method comprises first deploying one or more collar stents, and then deploying the endoluminal device radially within the one or more collar stents. In various embodiments, the collar stent may be radiopaque, may have inwardly protruding barbs for engaging the endoluminal device, and may have a region having a relatively low percentage of open area for bridging a portion of the main lumen having an intersecting lumen. The preconditioning step of implanting the collar stent may change the morphology of the lumen to more favorable morphology, such as from a non-circumferential geometry to a circumferential geometry.

WEAVE MODIFICATION FOR INCREASED DURABILITY IN GRAFT MATERIAL

An aneurysmal repair system that utilizes a weave modification to increase the durability of the graft material. An additional material is affixed to the graft material proximate the area where it is attached to the underlying stent structure. Alternatively, or in addition to, the additional material may be attached to the elements attaching the graft to the underlying stent structure.

TWISTING BIFURCATION DELIVERY SYSTEM

A catheter system comprises a catheter having an elongate catheter shaft such that a portion of the catheter shaft proximal a stent retaining region defines at least one bend that is bent around the longitudinal axis of a vessel. The catheter also has a side branch guidewire housing, defining a side branch guidewire lumen, and a side branch guidewire that extends through the side branch guidewire lumen.

CATHETER HAVING GUIDEWIRE CHANNEL

Catheter for delivering an expandable prosthetic device. The catheter has a guidewire channel for delivering a side branch guidewire to a side branch target site. An expandable prosthetic device can be loaded on to the distal end of the catheter.

DEVICES AND METHODS FOR APPROXIMATING THE CROSS-SECTIONAL PROFILE OF VASCULATURE HAVING BRANCHES

This disclosure is related to devices and related methods for isolating a treatment region in a human body from fluid pressure. In various embodiments, an implantable device for isolating a treatment region in a human body from fluid pressure comprises a first elongated segment, and a second elongated segment, and one or more branch segments in fluid communication with one of the first elongated segment and the second elongated segment. The elongated segments have a combined cross section that is substantially conformable to an intraluminal cross section of a body lumen into which they are implanted. A method of installing an implantable medical device into the body of a patient comprises deploying a first elongated segment, deploying a second elongated segment, and deploying one or more branch segments in a target region of a vasculature.

STENT-GRAFT HAVING FACING SIDE BRANCH PORTALS

In various embodiments, a device for treating disease of a vessel includes a stent graft (100) having an outer surface; and at least two side branch portals (110) each having a proximal ends and a distal end. Each distal end is substantially contiguous with the outer surface of the stent graft. In various other embodiments, the distal ends are generally axially further spaced apart than the proximal ends.

METHODS AND SYSTEMS FOR OSTIAL STENTING OF A BIFURCATION

A system for treating a bifurcation includes first and second delivery catheters, each having an expandable member. A stent having a side hole is disposed on the second delivery catheter. A portion of the first delivery catheter is disposed under a portion of the stent. The first delivery catheter is slidable relative to the second delivery catheter, and the first delivery catheter passes through the side hole. Expansion of the first expandable member expands a proximal portion of the stent in a main branch vessel, and expansion of the second expandable member expands a distal portion of the stent in a side branch vessel.

STENT GRAFT HAVING A MARKER AND A REINFORCING AND MARKER RING

A reinforcing and marker ring for a stent graft is disclosed. The reinforcing and marker ring comprises a plurality of turns of a substantially inextensible resilient wire in a circular shape and terminal ends at each end of the wire. The terminal ends each comprise a loop, each loop attachable to a stent graft having an opening or a fenestration so as to substantially lock a peripheral length of the circular shape. A marker winding is wound helically around the reinforcing wire, the marker winding being viewable on an image display system employing electromagnetic radiation so as to indicate the location of a periphery of the fenestration. The circular shape of the resilient wire, with the marker winding wound around it, is collapsible under radial pressure to form a squashed circular shape for loading into a delivery device, the squashed circular shape self -expandable back to a substantially circular shape upon release from the delivery device.

PROSTHETIC VALVE WITH AN ELASTIC STENT AND A SEALING STRUCTURE

The present disclosure concerns a prosthetic valve comprising a tubular elastic stent having a distal end and a proximal end with a passage extending from the distal end to the proximal end of the elastic stent, a valve positioned within the passage, and an annular sealing structure positioned on an exterior of the elastic stent at the distal end of the elastic stent, the sealing structure forming a protrusion and comprising an inflatable cuff.

ENDOVASCULAR PROSTHESIS

L'invention vise une prothèse endovasculaire comprenant une première armature expansible et une première chemise pour ladite première armature, ladite première armature et ladite première chemise formant un premier canal lorsque la première armature est à l'état expansé. La première armature et la première chemise présentent chacune au moins une ouverture disposées sensiblement en regard l'une de l'autre et à travers lesquelles un manchon est reçu, ledit manchon présentant une première extrémité et une deuxième extrémité, et dont le pourtour de ladite première extrémité est solidaire avec le pourtour de l'ouverture de la première chemise tandis que ladite deuxième extrémité s'étend à l'intérieur dudit premier canal.

ELECTROPHYSIOLOGICAL ENDOCARDIOLOGY TOOL

Apparatus and methods for pacing the heart. The apparatus may include, and the methods may involve, an elongated member having: a delivery lumen that is configured to traverse the heart wall, the lumen having a proximal opening for receiving the instrument and a distal opening for deploying the instrument; and an electrically conductive member that is configured to deliver to the heart wall a current that modifies a contraction frequency. The apparatus may include an access opening closure device that has: a distal end that is configured to be disposed interior the heart and contact endocardial tissue adjacent the access opening; and a proximal end that is configured to be disposed exterior the heart and contact heart tissue adjacent the access opening; and an electrode that is configured to discharge electrical energy into the heart wall to change the frequency. The apparatus may include an injectable needle pacing electrode.

ARTICULATED STENT

A connector (110) for connecting adjacent areas of adjacent segments (102) of an articulated stent, the connector includes a plurality of flexible links (112), wherein each of the flexible links includes a plurality of portions with each pair of neighboring portions having an area of inflection therebetween and wherein during expansion of said stent, said area of inflection of each flexible link remains inflected.

SYSTEM AND METHOD FOR ENDOLUMINAL GRAFTING OF BIFURCATED OR BRANCHED VESSELS

The present invention is a system, and method for endoluminal grafting of a main anatomical conduit (e.g., the aorta), various branch conduits (e.g., si de branch vessels such as the carotid, innominate, subclavian, intercostal, superior mesenteric, celiac, or renal arteries or furcation such as the iliac arteries) which emanate from the main anatomical conduit. The grafting system generally comprises a primary graft having at least one opening therein, at least one branch graft which is passable through the opening of the primary graft, and into the branch conduit(s) suc h that the proximal end of each branch graft is in substantially fluid tight sealing contact with the primary graft. Also disclosed is a specific system, a method for graftin g a bifurcated anatomical conduit (e.g., the aorta ilea bifurcation) through onl y a single access opening (puncture site or incision), and a new balloon anchoring guid e wire system.

UNIVERSAL ENDOVASCULAR GRAFTS

Universal eudovascular grafts are provided for evaluation and repair of damaged or aneurismal blood vessels. More particularly, the present invention relates to universal fenestrated and universal branched endografts for repair of blood vessels with branches, methods for implanting the endografts in the vessel and for making connection with one or more branches. The universal fenestrated endografts have a body with a first end, a second end, a first wall, a second wall, and an interior passage or lumen. The body further includes openings in communication with the passage at the first and second ends and one or more lateral fenestrations in communication with the lumen. The body further has a necked portion between the ends and a cannulation member. The universal branched endografts have a tubular body with a main lumen and four branch lumens. A large branch extends from the body. The four lumens are positioned about a circumference of the tubular body.

Staged deployment of expandable implant

AORTIC ENDOPROSTHESIS UNIVERSAL

Method for the automated production of a stent

AORTA IMPLANT STENT TYPE

Cet implant (1) comprend une portion couverte (10) présentant la membrane (6) sur l'ensemble de sa circonférence, et une portion découverte (11) présentant la membrane (6) sur une partie seulement de sa circonférence de manière à former une ouverture latérale (12). Selon l'invention : - l'armature déployable de l'implant (1) est formée, au niveau de ladite portion couverte (10), par une série d'anneaux plans (5) reliés à la membrane (6) mais non reliés entre eux ; - cette armature déployable comprend, du côté de la portion découverte (11) opposée à la portion couverte (10), une première portion tubulaire (2) d'ancrage à une aorte ; - cette armature déployable comprend, du côté de l'extrémité de la portion couverte (10) opposée à la portion découverte (11), une deuxième portion tubulaire (15) d'ancrage à l'aorte.

흐름 제한 스텐트-그래프트

... 현재 설명된 스텐트-그래프트는 공동을 형성하는 스텐트 프레임과 스텐트 프레임 둘레 주위로 연장되는 프레임 와이어를 포함한다. 스텐트 프레임은 공동 단면적이 흐름 제한 부분의 제1 길이를 따라 공동 최소 단면적까지 감소하고 흐름 제한 부분의 제2 길이를 따라 증가하도록 형성된다. 제1 길이는 공동 근위 단면적에서 공동 최소 단면적까지 연장되고 제2 길이는 공동 최소 단면적에서 공동 원위 단면적까지 연장된다. 스텐트-그래프트는 환자의 대동맥 내에 배치될 때 신장으로의 혈류를 증가시켜 울혈성 심부전 치료에 도움이 될 수 있다. 제공된 스텐트-그래프트는 요실금 치료를 돕기 위해 환자의 요도 내에 배치할 수도 있다.

acesso a ramificação por meio de um dispositivo médico bifurcado altamente maleável

Improved endoprosthesis anchoring and sealing

Described are various embodiments of an improved endoprosthesis that includes a generally cylindrical graft portion that extends along a longitudinal axis to define a flow passage and a plurality of stent hoops. The plurality of stent hoops are connected to the graft portion and disposed in a spaced apart relationship along the longitudinal axis. There is at least a first suture disposed along on the outer surface of the main body. The first suture connects at least two of the spaced apart stent hoops together. The first suture also includes unidirectional barbs (or multidirectional barbs) configured to reduce movement of the main body with respect to a direction of blood flow in an artery.

BRANCH ENDOGRAFT DELIVERY

A system for treating disease involving branching vessels of a mammal is provide. The system may include a main graft assembly (i) having a lumen permitting fluid flow therethrough, and (ii) configured to expand within, and contact a wall of, a first vessel of a mammal; and a branch graft assembly including a branch cover (i) having a cover lumen permitting fluid flow therethrough; and (ii) configured to expand within, and contact a wall of, a branch vessel that branches from the first vessel. The branch graft assembly may also include an expandable branch stent extending within the cover lumen. The branch graft assembly may further include a branch sheath (i) extending between the branch stent and the cover lumen, and (ii) constraining radial expansion of the branch stent within the cover lumen.

TREATMENT KIT, TREATMENT DEVICE, AND ASSOCIATED METHOD OF PRODUCTION

This kit has a first implant (16) defining a window (26), and a second implant (18) with a second tubular body (42) intended to be placed in the window (26). The second implant (18) has a member for retention of the second implant (18) with respect to the first implant. The kit comprises a ring (20) which retains the second implant (18), placed on the first tubular body (22), in the window (26) and delimits an insertion passage (60) for the second implant (18). The retention ring (20) is elastically deformable in the window (26) in order to permit a reversible increase of at least 20%, advantageously of at least 30%, in the external contour of the insertion passage (60).

BRANCHED STENT GRAFT DEVICE AND DEPLOYMENT

A device (10) for treating disease along a main vessel and at least one branch vessel extending from the main vessel includes a branch member (200, 202) for deployment in the branch vessel, the branch member having a branch lumen; and a main body (100) for deployment in the main vessel. The main body has a generally tubular wall (106) extending generally longitudinally between opposite first and second ends. The wall has an internal surface defining a main lumen and an opposite outer surface. The wall has a recessed portion (120) that is recessed relative to the outer surface of the wall and positioned between the first and second ends of the main body. The main body has an opening (130) formed in the recessed portion of the wall for receiving the branch member therethrough such that the branch lumen is in fluid communication with the main lumen.

ENDOVASCULAR PROSTHESIS

The invention relates to an endovascular prosthesis comprising a first expandable framework and a first lining for said first framework, said first framework and said first lining forming a first channel when the first framework is in the expanded state. The first framework and the first lining each have at least one opening, which openings are arranged substantially opposite each other and through which a sleeve is received, said sleeve having a first end and a second end, the perimeter of said first end being rigidly connected to the perimeter of the opening of the first lining, while said second end extends inside said first channel.

SIDE BRANCH STENT GRAFT

A joining arrangement between a main tube (3) and a side arm (5) in a side arm stent graft (1). The side arm (5) is stitched into an aperture (11) in the main tube and is in fluid communication with it. The aperture is triangular, elliptical or rectangular and the side arm is cut off at an angle to leave an end portion having a circumferential length equal to the circumference of the aperture. The side arm can also include a connection socket (76) comprising a first resilient ring (79) around the arm at its end, a second resilient ring (80) spaced apart along the arm from the first ring and a zigzag resilient stent (82) between the first and second rings. The zigzag resilient stent can be a compression stent. Both the main tube and the side arm are formed from seamless tubular biocompatible graft material.

BIFURCATED STENT AND DELIVERY SYSTEM

Systems for delivering a bifurcated stent to a bifurcation site comprise catheters and/or bifurcated stents delivered therefrom.

METHOD AND APPARATUS FOR EFFECTING AN AORTIC VALVE BYPASS, INCLUDING THE PROVISION AND USE OF A T-STENT FOR EFFECTING A DISTAL ANASTOMOSIS FOR THE SAME

A connector for joining a first hollow structure to the side wall of a second hollow structure, the connector comprising a fluid-constraining tube having a fluid-constraining neck extending therefrom, wherein the tube comprises a lumen having a first opening and a second opening and the neck comprises a lumen having a first opening and a second opening, the neck being joined to the tube so that the neck is in fluid communication with the tube intermediate the length of the tube, such that fluid enteπng the first opening of the tube can exit the second opening of the tube, and fluid entenng the first opening of the neck can exit the second opening of the tube at least the portions of the tube adjacent to the first opening of the tube and the second opening of the tube being biased radially outwardly so that they normally assume a radially-expanded configuration.

ENDOVASCULAR GRAFT FOR ANEURYSMS INVOLVING MAJOR BRANCH VESSELS

Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites include a main graft or stent-graft deployable in a main artery and a vent device or stent-graft deployable in a branch artery to maintain blood flow through the main artery and from the main artery to the branch artery. Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites may also include a main graft or stent-graft deployable in the main artery, a chimney graft or stent-graft deployable in both branch artery and the main artery to the branch artery and a gutter-sealing device associated with the chimney graft to prevent flow of blood among the chimney graft, the main graft and a wall of the main artery.

ENDOPROSTHESIS DEVICES AND METHODS OF USING THE SAME

Endoprosthesis assemblies and methods for using the same. In at least one embodiment, the endoprosthesis assembly comprises an endoprosthesis comprising an impermeable inner wall defining an endoprosthesis lumen sized and shaped to permit fluid to flow therethrough, a distal balloon positioned at or near a distal end of the endoprosthesis and capable of inflation to anchor the distal end of the endoprosthesis within a luminal organ, and a proximal balloon positioned at or near a proximal end of the endoprosthesis and capable of inflation to anchor the proximal end of the endoprosthesis within the luminal organ, wherein when the endoprosthesis assembly is positioned within the luminal organ at or near an aneurysm sac, inflation of the distal balloon and the proximal balloon effectively isolates the aneurysm sac and prevents fluid within the aneurysm sac from flowing past the distal balloon and the proximal balloon.

PERSONALIZED PROSTHESIS AND METHODS OF USE

A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.

Thoracic aorta stent graft with access region

A stent graft (2) for placement in the thoracic arch of a patient has a first tubular body portion (6) with a first lumen therein for placement in the ascending aorta of a patient and a second tubular body portion (8) to extend along the thoracic arch and down the descending aorta. The second tubular body portion is of a lesser diameter than the first tubular body portion. There is a step portion (10) between the first body portion and the second body portion. The step portion is joined to and continuous with the first portion and the second portion. A first side of each of the first body portion, the step portion and the second body portion are substantially aligned so that there is a step (18) defined on a second side opposite to the first side of the body portion. There is an aperture (30) in the step portion and an internal tube (32) extending from the aperture towards the first body portion. The internal tube is divided along part of its length into at least two smaller internal tubes ...

Multi-leaflet coupling for branch vessel connection

A prosthesis includes a tubular body of a graft material, a plurality of stents coupled to the tubular body, and a coupling. The coupling has a plurality of overlapping leaflets successively coupled to the tubular body around an opening formed in the graft material. The leaflets in a non-deployed configuration lay flush with the graft material of the tubular body and partially cover the opening, and the leaflets in a deployed configuration extend radially outward from the graft material of the tubular body. Delivery and deployment of a branch vessel prosthesis through the opening causes the leaflets to transform from the non-deployed configuration to the deployed configuration, and causes a diameter or width of a passageway defined by the leaflets to increase. Leaflet material properties, as well as size, shape, and sewing patterns on adjacent leaflets may be varied in order to vary the flexibility and/or orientation of the coupling.

Modular aneurysm repair system

The present invention is directed to a system, apparatus, and method for treating and/or repairing an aneurysm, preferably an aortic aneurysm, and most preferably, an abdominal aortic aneurysm. The systems, devices, and methods of the present invention include a first prosthesis or first prosthesis, and at least one second prosthesis for bypassing the aneurysm, and at least one third prosthesis for establishing a fluid flow channel from the abdominal aorta into another artery, such as a renal artery.

Selective stent crimping

Methods for crimping a stent on an expandable member of a delivery catheter, and devices and methods for treating a bifurcation are disclosed. A method for crimping includes positioning a stent having a first portion and a second portion over the expandable member, and non-uniformly crimping the stent to the expandable member. The method can include routing an elongate shaft under the second portion of the stent and through the side hole so as to be routed external to the first portion. The stent second portion can be crimped so that the elongate shaft can be slidably disposed relative to the stent second portion prior to deployment of the stent.

Fenestration with intrinsic means of selective closure incorporated to a tubular body and used in interventional cardiovascular procedures

A first arched surface (2) having a lower end fenestration (4), protruding from a tubular body (1), intersecting it along a closed oval perimeter (5). A second arched surface (7) placed with body (1) facing first surface (2), with an upper opening (8). Both surfaces (2,7) are related through this same perimeter (5) with identical cross sections. Body (1) and both arched surfaces (2,7) are made of a waterproof material. Surface (7) is elastically deformed along said perimeter (5), having means capable of displacing it between two operative positions. When both surfaces (2,7) have opposed convexities of different sign, they establish a passage (9) communicating inner tubular body (6) through said opening (8) and fenestration (4). When surface (7) acquires a same sign convexity to first surface (2), it settles against the inside of (2) closing passage (9), fenestration 4 and opening (8), with a sealing relationship.

FLARED STENTS AND APPARATUS AND METHODS FOR DELIVERING THEM

Apparatus and methods are provided for securing a stent-graft deployed within an aorta relative to a renal artery. A distal end of a delivery device may be introduced into the aorta, the distal end carrying a stent thereon. The distal end may be advanced through an opening in the stent-graft at least partially into the renal artery, and the stent may be expanded to anchor the stent-graft relative to the renal artery and/or secure the stent relative to the renal artery. An exemplary flaring stent is also disclosed.

Endoluminal vascular prosthesis

Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded by a flexible tubular membrane. A delivery catheter and methods are also disclosed.

Exterior supported self-expanding stent-graft

This is a medical device and a method of using it. The device is a foldable stent-graft which may be percutaneously delivered with (or on) an endovascular catheter or via surgical techniques or using other suitable techniques and then expanded. The stent-graft uses a kink-resistant stent structure and an interior graft which is attached to the stent in such a way that the graft does not kink and yet the stent is able to conform to curves in the blood vessel lumen. The expandable stent structure preferably has a helically deployed torsional member with an undulating shape which is wound to form the generally cylindrical shape deployed as the stent. The helical winding desirably is aligned to allow the undulations in adjacent turns of the helix to be in phase. The adjacent undulating shapes are held in that phased relationship using a flexible linkage, typically made of a polymeric material. The stent may also be of a ring configuration. The stent may be flared to promote smooth blood flow ...

Vascular prosthesis

The subject invention concerns vascular prosthetic devices and methods for ascending aorta and/or valve replacement in humans and animals. In one embodiment, a device of the invention includes a vessel-like structure having a first end adapted for surgical attachment to a left ventricle, a second end adapted for surgical attachment to an aorta, and, interposed between the first and second ends, a sinus portion configured in the shape of the sinuses of Valsalva in a human aortic valve.

Endovascular aneurysm repair systems and methods

Systems and methods introduce a tissue fastener applier to apply tissue-piercing fasteners to a prosthesis sequentially along a path established by the directing device that, between fastener applications, is manipulated into orientation with different desired fastening sites, until a plurality of tissue-piercing fasteners are placed, one-at-a-time, in the prosthesis.

Stent Graft Having A Marker And A Reinforcing And Marker Ring

A reinforcing and marker ring for a stent graft is disclosed. The reinforcing and marker ring comprises a plurality of turns of a substantially inextensible resilient wire in a circular shape and terminal ends at each end of the wire. The terminal ends each comprise a loop, each loop attachable to a stent graft having an opening or a fenestration so as to substantially lock a peripheral length of the circular shape. A marker winding is wound helically around the reinforcing wire, the marker winding being viewable on an image display system employing electromagnetic radiation so as to indicate the location of a periphery of the fenestration. The circular shape of the resilient wire, with the marker winding wound around it, is collapsible under radial pressure to form a squashed circular shape for loading into a delivery device, the squashed circular shape self-expandable back to a substantially circular shape upon release from the delivery device. The marker winding defines a curved passageway around the resilient wire of the reinforcing ring, the curved passageway having an internal diameter D, wherein the marker winding is helically wound with a pitch providing at least one winding per length D along the reinforcing wire of the reinforcing ring. The marker winding may be a radiopaque gold wire wound around a nitinol reinforcing wire.

Endovascular aneurysm repair system

Method and apparatus for implanting radially expandable prostheses in the body lumens rely on tacking or anchoring of the prostheses with separately introduced fasteners. The prostheses may be self-expanding or balloon expandable. After initial placement, a fastener applier system is introduced within the expanded prostheses to deploy a plurality of fasteners at least one prosthesis end, usually as each end of the prosthesis. The fasteners are usually helical fasteners which are delivered from a helical track in the fastener applier by rotation with a rotator wire. The fasteners will be applied singly, typically in circumferentially spaced-apart patterns about the interior of each end of the prosthesis.

Modular grafting system and method

A system and method for treating and repairing complex anatomy characterized by a plurality of vessel portions oriented at various angles relative to each other. The system including a graft device that is capable of being assembled in situ and has associated therewith a method that avoids the cessation of blood flow to vital organs. A delivery catheter system and various graft supporting, mating and anchoring structures are additionally included.

Devices and methods for in situ fenestration of a stent-graft at the site of a branch vessel

The present disclosure includes a stent-graft comprising a first portion that is configured to engage a vessel wall, a second portion that is configured not to engage the vessel wall, and a perfusion window that is configured to permit blood flow. The stent-graft may further comprise a transition portion between the first portion and the second portion, and the perfusion window may be formed in the first portion, the second portion, and/or the transition portion. In a variety of embodiments, one of the first and the second portion may have a smaller diameter than the other. Similarly, in a variety of embodiments, the transition portion may be frustoconically shaped.

Stent Graft System

The stent graft system in accordance with the present invention has a trunk, a left subclavian tube, a left common carotid tube and a brachiocephalic tube. The trunk is tubular and expandable and has a descending end, an ascending end, a left subclavian mount, a left common carotid mount and a brachiocephalic mount, for receiving the aforementioned branch tubes that are elastic and self-expandable for respectively connecting the left subclavian artery, the left common carotid artery and the brachiocephalic artery to the trunk. With the above-described structure, the present invention allows fast determination of a suitable trunk and branch tubes for a patient and allows a medical institute to prepare compatible branch tubes and trunks for a composite stent graft system instead of numerous stent grafts of various combinations of differently sized tubular bodies and branches, wherein the former requires significantly less warehousing cost than the latter.

Paraplegia prevention valve for stent grafts

A stent graft defining a main lumen bounded by a wall of graft material is disclosed. The stent graft has a valve portion between proximal and distal portions. The valve portion is formed by a wall portion having a part-circumferential double layer portion comprising an inner underlap portion and an outer overlap portion, the double layer portion forming a passageway parallel to the main lumen. The passageway has an entrance mouth and an exit mouth. The passageway has an open condition where the underlap and overlap portions are spaced apart to form a vent lumen. The wall portion is broken by a narrow cut. The cut is openable by relative radial movement between its edges. This allows re-perfusion of an aneurism and perfusion of blood from within the lumen out towards blood vessels such as intercostals and can assist in minimising the chance of paraplegia.

Thoracic aorta stent graft

A stent graft for placement in the thoracic arch of a patient has a tubular body defining a main lumen therethrough, a plurality of zig zag stents along the tubular body, each of the stents comprising a plurality of struts and bends, the bends being between adjacent struts. At least a first stent and an adjacent second stent having at least a pair of adjacent bends on the first stent aligned with an adjacent pair of bends on the second stent, whereby a first pair of adjacent struts of the first stent and a second pair of adjacent struts of the second adjacent stent together define a diamond shape region. A recess is within the diamond shaped region with the recess extending into the lumen of the tubular body. A fenestration extending into the tubular body within the recess in the diamond shaped region and a graft tube leading from the fenestration into the main lumen. There can be one, two or three diamond shaped regions, recesses, fenestrations and graft tubes Proximally of the or each diamond shaped region the tubular body has a first diameter, distally of the diamond shaped region the tubular body has a second diameter and in the region of the tubular body around the diamond shaped region the tubular body has a third diameter, the first diameter being greater than the second diameter and both the first and second diameter being greater than the third diameter whereby a central region is defined which will allow circumferential blood flow during an operation out of the graft tube into the recess and then into the central region.

Paraplegia prevention stent graft

A stent graft ( 10 ) for deployment into the aorta of a patient has a tubular body ( 12 ) with a proximal portion ( 14 ) of a selected diameter and a portion ( 16 ) of a reduced diameter less than the selected diameter distal of the proximal portion and a tapered portion ( 18 ) extending between the proximal portion and the portion of reduced diameter. Low profile side arms ( 26, 28, 30, 32 ) are provided in the portion of reduced diameter and/or the tapered portion. The side arms are for connection of an arm extension to an aortic branch vessel. A paraplegia prevention vent tube ( 34 ) is provided in fluid communication with the main lumen and open to external of the tubular body in the region defined by the portion of reduced diameter and the tapered portion. The paraplegia prevention vent tube is not intended to be connected to a side branch of the aorta but is intended, and is so constructed and arranged, to provide temporary perfusion to external of the stent graft after deployment of the stent graft into the aorta and is intended, and is so constructed and arranged, to be subsequently blocked.

Branch vessel prostheses

The present embodiments provide a branch vessel prosthesis for placement at least partially between a main vessel and a branch vessel of a patient. The branch vessel prosthesis has a graft including a generally tubular body of a biocompatible material. At least one stent is coupled to a proximal region of the graft, and at least one stent is coupled to a distal region of the graft. The proximal region of the graft includes a generally straight configuration in an expanded deployed state that is substantially parallel to a longitudinal axis of a main vessel. The distal region of the graft includes a generally straight configuration in the expanded deployed state that is substantially parallel to a branch vessel. A curvature of a central region varies an angle in which the distal region of the graft is disposed relative to the proximal region.

Actively Controllable Stent, Stent Graft, Heart Valve and Method of Controlling Same

Sealable and repositionable implant devices are provided with features that increase the ability of implants such as endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, the assembly having adjustable elements and being operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.

Endoluminal prosthesis with steerable branch

An endoluminal prosthesis may include a tubular main graft body including a sidewall and proximal and distal ends. A first stent may be positioned near the proximal end of the main graft body. A second stent may be positioned adjacent to and distal of the first stent. An opening in the sidewall may be positioned longitudinally between a peak of the first stent and a valley of the second stent. A tubular branch may be disposed in the opening. The branch may include first and second end openings. The branch may be flexibly orientable between a retrograde configuration in which the first end opening is oriented toward the distal end and the second end opening is oriented toward the proximal end and an antegrade configuration in which the first end opening is oriented toward the proximal end and the second end opening is oriented toward the distal end.

Surgical Stapling System

A system is provided for joining two tubular structures by a surgical stapling procedure. The system includes a series of sizers, a specifically designed graft, a loading unit, a wand, a tourniquet, and a stapling instrument. As a result, a plurality of staples may be simultaneously deployed quickly and accurately in a circumferential pattern so as to join together two tubular structures. The system may be used in either an open surgical procedure or laparascopically.

Branch stent graft deployment and method

A deployment device for deploying a self-expanding fenestrated stent graft. The device includes a fenestrated stent graft retained on an introducer. The introducer includes a main catheter and an auxiliary catheter preloaded within the introducer and extending from distal the distal end of the stent graft, into the lumen of the stent graft and through the fenestration.

Device for endovascular aortic repair and method of using the same

A device and method for endovascular repair of a patient's aorta is disclosed. The device includes a frame component that has a balloon-expandable frame and a self-expanding frame secured to the balloon-expandable frame. The device also includes a valve element positioned at the proximal end of the frame component. The device may include another prosthetic component that may be secured to the frame component. The prosthetic component may include at least one conduit configured to receive a covered stent.

Electrophysiological endocardiology tool

Apparatus and methods for pacing the heart. The apparatus may include, and the methods may involve, an elongated member having: a delivery lumen that is configured to traverse the heart wall, the lumen having a proximal opening for receiving the instrument and a distal opening for deploying the instrument; and an electrically conductive member that is configured to deliver to the heart wall a current that modifies a contraction frequency. The apparatus may include an access opening closure device that has: a distal end that is configured to be disposed interior the heart and contact endocardial tissue adjacent the access opening; and a proximal end that is configured to be disposed exterior the heart and contact heart tissue adjacent the access opening; and an electrode that is configured to discharge electrical energy into the heart wall to change the frequency. The apparatus may include an injectable needle pacing electrode.

Branched stent graft device and deployment

A device for treating disease along a main vessel and at least one branch vessel extending from the main vessel includes a branch member for deployment in the branch vessel, the branch member having a branch lumen; and a main body for deployment in the main vessel. The main body has a generally tubular wall extending generally longitudinally between opposite first and second ends. The wall has an internal surface defining a main lumen and an opposite outer surface. The wall has a recessed portion that is recessed relative to the outer surface of the wall and positioned between the first and second ends of the main body. The main body has an opening formed in the recessed portion of the wall for receiving the branch member therethrough such that the branch lumen is in fluid communication with the main lumen.

Medical device delivery system and deployment method

An aortic stent-graft may include a tubular graft extending from a proximal end to a distal end, the graft comprising a proximal sealing portion and an intermediate portion, wherein a proximal end of the intermediate portion abuts the distal end of the proximal sealing portion. At least one sealing stent may be attached to the proximal sealing portion. A first fenestration window is disposed in the intermediate portion. The first fenestration window has a length determined by the equation L=1.23*D−24 millimeters, where L is the length of the first fenestration window. D is between about 24 millimeters and 45 millimeters.

Debranching Great Vessel Stent Graft and Methods for Use

A debranching Great vessel stent graft and methods for its use, where the stent graft comprises, a main body stent graft with a first bifurcation defining a first leg and a second leg, the main body stent graft has distal and proximal ends, the main body stent graft has a diameter at the proximal end in the range from about 18 mm to about 28 mm, the first leg and the second leg each have a diameter in the range from about 12 mm to about 18 mm, the distance from the proximal end of the main body to the distal end of the first leg is in the range from about 30 mm to about 50 mm, and the distance from the proximal end of the main body to the distal end of the second leg is in a range from about 50 mm to about 70 mm.

Stent-graft prosthesis for placement in the abdominal aorta

A self-expanding main vessel stent-graft includes a trunk portion configured for placement within the abdominal aorta and a bifurcated portion configured for placement above the aortic bifurcation of the common iliac arteries. The trunk portion includes a proximal end section having an anchor stent and a seal stent that accommodates a scallop or open-top fenestration; a suprarenal body section having at least one stent of variable stiffness to accommodate branch vessel prosthesis deployed alongside the main vessel stent-graft; a branch connection section having opposing couplings for connecting the main vessel stent-graft to branch vessel prostheses deployed within the renal arteries; an infrarenal body section having at least one stent of uniform stiffness; and a transition section for transitioning into the bifurcated portion. The main vessel stent-graft is configured to treat short-neck infrarenal, juxtarenal, and/or suprarenal aneurysms in a wide range of patient anatomies.

Fenestrated stent grafts

A stent graft ( 1 ) including a tubular wall ( 3 ) with at least one fenestration ( 40 ) including a peripheral ( 37 ) reinforcement around at least part of the fenestration. There can also be a tubular extension ( 15 ). The side arm includes a stent ( 19 ) and a cover ( 17 ) and extends from and is in fluid communication with the fenestration and the stent graft. The stent may be a self expanding stent. The ring and/or tubular extension provides better support and sealing for an extension arm. The fenestration ( 40 ) can be circular or if towards the ends of the stent graft may be in the form of a U-shape ( 50 ) with an open end.

STAGED DEPLOYMENT OF EXPANDABLE IMPLANT

An endoprosthesis delivery system includes an expandable endoprosthesis including a side branch portal, a first primary sleeve releasably constraining a proximal portion of the expandable endoprosthesis to a collapsed configuration, a second primary sleeve in parallel with the first primary sleeve, the second primary sleeve releasably constraining a distal portion of the expandable endoprosthesis to the collapsed configuration, and a secondary sleeve within the first primary sleeve. Upon release of the first primary sleeve, the secondary sleeve releasably constrains the proximal portion of the expandable endoprosthesis to a partially expanded configuration allowing access to the side branch portal via the partially expanded proximal portion of the expandable endoprosthesis. 1. An endoprosthesis delivery system comprising:an expandable endoprosthesis including a side branch portal;a first primary sleeve releasably constraining at least a first portion of the expandable endoprosthesis toward a collapsed configuration;a secondary sleeve overlapping with the first primary sleeve, wherein upon release of the first primary sleeve, the secondary sleeve releasably constrains a second portion of the expandable endoprosthesis to a partially expanded configuration allowing access to the side branch portal via the partially expanded portion of the expandable endoprosthesis;a side branch component configured for delivery through the side branch portal via the partially expanded portion of the expandable endoprosthesis.2. The endoprosthesis delivery system of claim 1 , wherein:the expandable endoprosthesis defines a central lumen, further comprising a first guidewire extended through the central lumen; anda second guidewire extended through the partially expanded portion of the endoprosthesis and the side branch component.3. The endoprosthesis delivery system of claim 1 , further comprising a second primary sleeve in parallel with the first primary sleeve claim 1 , the second ...

SINGLE MULTIBRANCH STENT DEVICE ASSEMBLY AND METHOD

The techniques of this disclosure generally relate to an assembly including a single multibranch stent device. The single multibranch stent device includes a main body, a proximal coupling extending radially from the main body, and a distal coupling extending radially from the main body. The main body, the proximal coupling, and the distal coupling are permanently coupled to one another and the single multibranch stent device is a single piece. By forming the single multibranch stent device as a single piece, the single multibranch stent device can be deployed in a single deployment thus simplifying the deployment procedure. 1. An assembly comprising: a main body;', 'a proximal coupling extending radially from the main body; and', 'a distal coupling extending radially from the main body, wherein the main body, the proximal coupling, and the distal coupling are permanently coupled to one another;, 'a single multibranch stent device comprisinga first guidewire prewired within the proximal coupling; anda second guidewire prewired within the distal coupling.2. The assembly of wherein the main body comprises a proximal opening at a proximal end and a distal opening at a distal end claim 1 , wherein the distal coupling is located between the distal opening and the proximal coupling.3. The assembly of wherein the proximal coupling is located between the distal coupling and the proximal end.4. The assembly of wherein the main body comprises a lumen extending between the proximal opening and the distal opening.5. The assembly of wherein the proximal coupling comprises a lumen fluidly coupled to the lumen of the main body claim 4 , and wherein the distal coupling comprises a lumen fluidly coupled to the lumen of the main body.6. The assembly of wherein the main body comprises a first longitudinal axis claim 1 , the proximal coupling comprises a second longitudinal axis extending radially from the first longitudinal axis claim 1 , and the distal coupling comprises a third ...

METHOD FOR AORTIC REPAIR AND AORTIC REPLACEMENT

An endovascularly deployed prosthetic includes a portion for being positioned within an ascending aorta. The prosthesis includes a replacement aortic valve on a proximal end thereof. The prosthesis includes an increased diameter portion that seals against the aorta at a more distal portion, and a pair of conduits extend from the increased diameter portion to the coronaries for fluidly coupling the coronaries to the prosthesis. 110-. (canceled)11. A method of implanting a transcatheter aortic valve assembly , comprising:endovascularly positioning a guide wire through the aortic valve of a patient;endovascularly positioning the transcatheter aortic valve assembly through the aortic valve of the patient, wherein the transcatheter aortic valve assembly has a radially compressed orientation and a radially expanded orientation,wherein the transcatheter aortic valve is positioned so that an outer seal of the transcatheter aortic valve assembly is in overlapping radial alignment with native valve leaflets of the patient, wherein the outer seal comprises a plurality of outwardly extending fibers that form the outer seal;inflating a balloon assembly to expand the transcatheter aortic valve assembly from the radially compressed orientation into the radially expanded orientation,wherein the outwardly extending fibers are pressed into engagement with the native leaflets of the patient to treat paravalvular leaks.12. The method of claim 11 , wherein the transcatheter aortic valve assembly includes an outer frame claim 11 , wherein the outer frame is formed from a metallic material and defines an open cell configuration.13. The method of claim 12 , wherein the transcatheter aortic valve assembly includes an inner frame that engages a prosthetic heart valve having prosthetic leaflets claim 12 , wherein the inner frame includes a cylindrically extending graft covering extending at least partially radially outwardly of the prosthetic heart valve and radially inwardly of the outer ...

Pre-loaded multiport delivery device

A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. The indwelling guide wire are configured to receive the access sheaths. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertization of a side branch or target vessel through the fenestration or be used to stabilize the access sheath during catheterization, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.

Devices and methods for anatomic mapping for prosthetic implants

A method of generating a patient-specific prosthetic includes receiving anatomic imaging data representative of a portion of a patient's anatomy. A first digital representation of the anatomic imaging data is defined. The first digital representation of the anatomic imaging data is modified. A second digital representation of the portion of the patient's anatomy is defined based on the modifying of the first digital representation of the anatomic imaging data. A patient-specific prosthetic template of the portion of the patient's anatomy is generated based at least in part on the second digital representation of the anatomic imaging data.

ENDOPROSTHESIS FOR ENDOVASCULAR TREATMENT OF THORACIC-ABDOMINAL AORTIC ANEURYSMS OR DISSECTIONS AND ENDOPROSTHESIS FOR ENDOVASCULAR TREATMENT OF ABDOMINAL AORTIC ANEURYSMS OR DISSECTIONS WHICH COMPROMISE THE ILIAC ARTERIES

The present invention relates to an endoprosthesis for endovascular treatment of thoracic-abdominal aortic aneurysms or dissections, wherein the endoprosthesis has a proximal region, an intermediate region and a distal region, comprising five inner cylinders parallel to the longitudinal axis of the endoprosthesis, said inner cylinders, having elliptical apertures in the intermediate region. The present invention also relates to an endoprosthesis for endovascular treatment of abdominal aortic aneurysms or dissections which compromise the iliac arteries, wherein the endoprosthesis has a proximal region, an intermediate region and a distal region, comprising an inner cylinder parallel to the longitudinal axis of the endoprosthesis, said inner cylinder having an elliptical aperture in the intermediate region. 1123457911131579111368101214. Endoprosthesis for endovascular treatment of thoracic-abdominal aortic aneurysms or dissections , said endoprosthesis () comprising a proximal region () , an intermediate region () and a distal region () , wherein it has five internal cylinders () , () , () , () , and () , parallel to the longitudinal axis of the endoprosthesis () , said internal cylinders () , () , () , () , and () being provided with elliptical openings () , () , () , () , and () arranged in said intermediate region ().2505152535450545552. Endoprosthesis for endovascular treatment of thoracic-abdominal aortic aneurysms or dissections , said endoprosthesis () comprising a proximal region () , an intermediate region () and a distal region () , wherein it has an internal cylinder () , parallel to the longitudinal axis of the endoprosthesis () , said internal cylinder () being provided with and elliptical opening () in said intermediate region (). The present invention belongs to the field of prostheses implantable inside the human body, especially to the field of devices that prevent collapse of tubular structures of the body, such as endoluminal vascular prostheses or ...

INTRODUCER FOR A SIDE BRANCH DEVICE

An introduction arrangement for a fenestrated or branched stent graft () intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer () has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator () and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath () on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter () extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire () extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery. 1. An introduction arrangement for a branched stent graft intended for deployment into the lumen of a vessel having a blind vessel extending therefrom; the branched stent graft having a main tubular body having a distal end and a proximal end with a main lumen therethrough , a side arm extending from the main body and having a side arm lumen therethrough and in fluid communication with the main lumen , the introduction arrangement including an introducer , the introducer having a distal end intended to remain outside a patient in use and a proximal end , the proximal end having a nose cone dilator and an arrangement to retain the branched stent graft thereon distally of the nose cone dilator , the branched stent graft being retained on the introducer and a sheath on the introducer extending over the branched stent graft to the nose cone dilator , an indwelling catheter extending from the distal end of the introducer through an introducer lumen in the introducer to the branched stent graft , exiting from the introducer lumen at a distal end of the branched stent graft and entering the distal end of the side ...

Introducer for a side branch device

An introduction arrangement for a fenestrated or branched stent graft ( 13 ) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer ( 1 ) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator ( 11 ) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath ( 15 ) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter ( 21 ) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire ( 29 ) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.

PROSTHESIS HAVING PIVOTING FENESTRATION

The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. 1. A prosthesis , comprising:a graft having a tubular body and a surface comprising a first biocompatible material;at least one fenestration having a diameter extending from a sidewall of the graft;a first perimeter having a first diameter and surrounding the fenestration;a band of flexible material attached to and surrounding the first perimeter and having a flexible frame;a second perimeter attached to and surrounding the band of flexible material and having a second diameter greater than the first perimeter diameter;where the band of material has a first diameter substantially the same as the first perimeter diameter and a second diameter substantially the same as the diameter of the second perimeter, and where the diameter of the band of material decreases in a direction away from the surface of the graft from the second perimeter to the first perimeter; andwhere each fenestration is pivotable in any direction away from an axis perpendicular to a longitudinal axis of the prosthesis.2. The prosthesis of claim 1 , wherein the flexible frame includes a plurality of support units.3. The prosthesis of claim 1 , wherein the band of material has a concave or convex orientation relative to the surface of the graft.4615. The prosthesis of claim 1 , wherein the first diameter of the band is about mm and the second diameter of the band is about mm.5. The prosthesis of claim 5 , wherein the first perimeter claim 5 , the band of material claim 5 , and the second perimeter form a hemispherical shape and are substantially concentric when positioned in the same plane.6. A prosthesis for treatment of a main vessel ...

DEVICE FOR ENDOVASCULAR AORTIC REPAIR

An endovascularly deployed prosthetic includes a portion for being positioned within an ascending aorta. The prosthesis includes a replacement aortic valve on a proximal end thereof. The prosthesis includes an increased diameter portion that seals against the aorta at a more distal portion, and a pair of conduits extend from the increased diameter portion to the coronaries for fluidly coupling the coronaries to the prosthesis. 110-. (canceled)11. A transcatheter heart valve assembly comprising: a first open cell portion; and', 'a second open cell portion extending from and continuous with the first open cell portion and defining a construction that differs from the construction of the first open cell portion;, 'an outer frame, wherein the outer frame is formed from a metallic material and definesan inner frame that houses a prosthetic heart valve, wherein the inner frame is a graft covering extending around at least a portion of the prosthetic heart valve for providing sealing to the heart valve, wherein the graft covering covers the first open cell portion but does not extend to the second open cell portion,wherein the outer frame is secured to the graft covering by a plurality of stitches,a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks, wherein the sealing material includes a plurality of outwardly extending fibers that extend outwardly of the outer frame to form the sealing material, wherein the sealing material is attached to the first open cell portion of the outer frame and extends at least a majority of a height of the first open cell portion,wherein the valve assembly is balloon expandable and expansion of the valve assembly presses the sealing material against native leaflets of the aorta of the patient,wherein the valve assembly has a radially compressed orientation and a radially expanded orientation.12. The valve assembly of claim 11 , ...

PERSONALIZED PROSTHESIS AND METHODS OF USE

A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed. 1. A personalized prosthesis , said prosthesis comprising:A radially expandable prosthesis, wherein the prosthesis is personalized prior to implantation thereof such that the prosthesis substantially matches a shape and a volume of a treatment site.2. A method of treating a treatment site , said method comprising:providing a personalized prosthesis;delivering the prosthesis to the treatment site; andradially expanding the prosthesis into engagement with the treatment site such that the prosthesis substantially matches a shape and a volume of the treatment site. The present application is a continuation of U.S. patent application Ser. No. 15/628,431 (Attorney Docket No. 44600-703.302) now U.S. Pat. No. filed Jun. 20, 2017 which is a continuation of U.S. patent application Ser. No. 14/850,586 (Attorney Docket No. 44600-703.401) now U.S. Pat. No. 9,744,060 filed Sep. 10, 2015 which is a divisional application of U.S. patent application Ser. No. 13/663,160 (Attorney Docket No. 44600-703.201, formerly 45045-703.201) filed Oct. 29, 2012 now abandoned, which is a non-provisional of and claims the benefit of U.S. Provisional Patent Application No. 61/554,099 (Attorney Docket No. 44600-703.101, formerly 45045-703.101) filed Nov. 1, 2011; the entire ...

BRANCH ENDOGRAFT DELIVERY

A system for treating disease involving branching vessels of a mammal system can include a main graft assembly (i) having a lumen permitting fluid flow therethrough, and (ii) configured to expand within a first vessel of a mammal; and a branch graft assembly including a branch cover (i) having a cover lumen permitting fluid flow therethrough; and (ii) configured to expand within a branch vessel that branches from the first vessel. The branch graft assembly may also include an expandable branch stent extending within the cover lumen. The branch graft assembly may further include a branch sheath (i) extending between the branch stent and the cover lumen, and (ii) constraining radial expansion of the branch stent within the cover lumen. 1. (canceled)2. A graft system for treating branching blood vessels of a mammal , said branch assembly comprising:a main graft assembly including a main stent with a main stent lumen and a main cover with a main cover lumen; anda branch graft assembly including a branch stent with a branch stent lumen and a branch cover with a branch cover lumen, wherein the branch cover is coupled with the main cover;a branch sheath (i) positioned fully over the expandable branch stent and beneath the branch cover, and (ii) constraining radial expansion of the branch stent, wherein the expandable branch stent is attached to the branch cover along at least a part of a perimeter of the branch cover in order to inhibit distal movement of the branch sheath within the branch cover lumen while said branch graft assembly is being advanced through a first vessel and into a branch vessel;an outer sheath which constrains the branch graft assembly to lie substantially in parallel against the main graft assembly while the main graft assembly and the branch graft assembly are being advanced through the first vessel;such that (i) retracting the outer sheath from over the main graft assembly and the branch graft assembly laterally releases the branch graft assembly ...

SYSTEMS AND METHODS WITH FENESTRATED GRAFT AND FILLING STRUCTURE

A system includes a graft body and a filling structure. The graft body has a fenestration in a side surface through which a support structure is insertable. The filling structure has an internal volume that is tillable with a filling medium and is configured to have a conduit through the internal volume through which the support structure is insertable. The conduit in the filling structure is alignable with the fenestration in the graft body such that the support structure is insertable through both the conduit in the filling structure and the fenestration in the graft body. 1. A system , comprising:a graft body with a fenestration in a side surface through which a support structure is insertable; anda filling structure defining an internal volume that is fillable with a filling medium and configured with a conduit through the internal volume through which the support structure is insertable.2. The system of claim 1 ,wherein the conduit in the filling structure is alignable with the fenestration in the graft body such that the support structure is insertable through both the conduit in the filling structure and the fenestration in the graft body.3. The system of claim 1 ,wherein the fenestration in the graft body and the conduit in the filling structure are alignable with a renal artery.4. The system of claim 1 , further comprising:a stent attached to the graft body at a portion of the graft body that is entirely above a location of the fenestration in the graft body.5. The system of claim 1 ,wherein the graft body is configured to have an enlarged portion having slack graft material to allow for the fenestration to be moved to align the fenestration with an artery.6. The system of claim 1 ,wherein the filling structure surrounds at least a portion of the graft body.7. The system of claim 1 ,wherein the filling structure is configured such that the conduit in the filling structure is an opening with a shutter that is closable around the support structure after the ...

PROTHESIS HAVING PIVOTING FENESTRATION

The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, and a second perimeter attached to and surrounding the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape. In one aspect, the prosthesis includes at least three pivotable fenestrations, 1. An endoluminal prosthesis , comprising:a graft having a tubular body and a surface comprising a first biocompatible material;a stent frame having a plurality of stent units attached to the graft about the surface of the graft and arranged in longitudinally spaced rows, at least one of the stent units comprising a plurality of struts interconnected by apices;at least three fenestrations disposed through a sidewall of the graft, each fenestration having a diameter;a first perimeter having a first diameter and surrounding each of the fenestrations;each first perimeter having a band of flexible material attached to and surrounding the perimeter, the band of flexible material having a depth relative to a surface plane of the tubular body; andeach band of flexible material having a second perimeter attached to and surrounding the band of flexible material;where the first perimeters, the bands of flexible material, and the second perimeters have a geometric shape and where each fenestration is pivotable in any direction away from an axis perpendicular to a longitudinal axis of the prosthesis, where at least two of the fenestrations are positioned on opposing sides of the graft.2. The prosthesis of claim 1 , where the ...

Frame structures, stent grafts incorporating the same, and methods for extended aortic repair

One aspect of the present disclosure can include a frame structure adapted for use with a stent graft. The frame structure can include a scallop region and a Z-form region. The scallop region can have a first end portion, a second end portion, and a perimeter that defines an aperture. The Z-form region can extend from the scallop region and include a plurality of Z-shaped struts, each of which has a first end and a second end that is connected to the scallop region at different points so as to form a central frame structure lumen. The second end portion of the scallop region can include a backstop that is deployable from a first flattened configuration to a second erect configuration. The backstop, in the second erect configuration, is sized and dimensioned to extend into a lumen of an aortic branch vessel.

BRANCHED STENT GRAFT, DELIVERY SYSTEM COMPRISING SAME AND METHOD OF FABRICATING SAME

A branched stent graft, a convey system comprising thereof and manufacturing method thereof, the branched stent graft includes a main body () and a side branch (), at least a portion of a lowermost stent section of the side branch () closest to the main body () is not stitched to the cover of the side branch from a lower end to an upper end, the at least a portion of the lowermost stent section is located on a side of the side branch corresponding to a folding direction of the side branch. After deployed, the branched stent graft has an effective supporting force at the base portion of the side branch. In addition, during the deployment of the stent, the side branch can expand to a maximal extent even when the positioning is slightly inaccurate. Further, vascular stenosis or occlusion will not be caused even when subsequent endothelialization occurs.

STENT GRAFT

The stent graft () comprises a cylinder comprising a graft material in the form of a film and a stent that supports the cylinder. Further, the stent graft () is inserted within a region from the ascending aorta to the sinus of valsalva, and the stent graft comprises cylindrical body section () arranged in the ascending aorta and the sinus of valsalva section () arranged in the sinus of valsalva and having an inner diameter larger than that of the body section (). 14-. (canceled)5. A stent graft comprising a cylinder comprising a graft material in the form of a film , and a stent that supports the cylinder , characterized in that:an open window is formed in the cylinder,roentgen markers are arranged inside an inner periphery of the open window, anda site of the window is a bare stent.6. (canceled)7. The stent graft according to claim 5 , whereinthe open window is circular when the stent graft is extended, and the roentgen markers are arranged in four directions of the open window.8. The stent graft according to claim 5 , whereinthe roentgen markers are soldered to the stent.9. The stent graft according to claim 5 , whereinthe stent graft is inserted in aortic arch; andthe open window is formed so as to enclose the openings of left subclavian artery, left common carotid artery, and brachiocephalic artery branching from the aortic arch. The present disclosure relates to stent grafts.Aortic diseases include cases of aortic aneurysms and aortic dissections. The aortic aneurysm refers to generation of aneurysm which bulges out like a lump in a part of the aorta; and arteriosclerosis is thought to be the main cause of the onset of the aortic aneurysm. The aortic aneurysm is a dangerous disease that exhibits no noticeable subjective symptoms such as pain even when the enlargement of the aortic aneurysm advanced and causes the rupture of the aorta in the course of time due to failure to withstand blood pressure, resulting in massive bleeding. Further, the aortic dissection ...

LOW PROFILE NON-SYMMETRICAL STENT

Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component. 120-. (canceled)21. A stent-graft system for treatment of a medical condition , the stent-graft system comprising:a proximal component comprising a graft having proximal and distal ends, and further comprising a stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where at least one of the distal apices of the stent is attached to the graft using one or more sutures,where each proximal apex comprises a first curved portion and each distal apex comprises a second curved portion, where the first curved portion and the second curved portion each comprises at least one radius of curvature, and the radius of curvature of at least one of the proximal apices is greater than the radius of curvature of at least one of the distal apices; anda ...

Treatment of tricuspid insufficiency

A tricuspid insufficiency treatment device includes a vena cava member ( 12 ) implantable in a vena cava of a patient. The vena cava member ( 12 ) is formed with a fenestration ( 14 ) and further includes a blocking member ( 16 ) arranged to block and unblock the fenestration ( 14 ).

STENT GRAFT WITH INTERNAL CONSTRAINING MECHANISM

A stent graft assembly having a tubular body and a constraining patch attached to the interior surface of the tubular body. The constraining patch delineates a small passageway close to the inner surface of the tubular body. A cannula may extend through the passageway. 1. A stent graft assembly comprising:a tubular body having a first open end, a second open end, a main lumen between the first open end and the second open end, and an inner surface surrounding the main lumen;a patch disposed in the main lumen and attached to the inner surface and defining a longitudinally extending passageway between the inner surface and the patch, the patch having a first unattached end and a second unattached end;wherein the passageway is in fluid communication with the main lumen through the first unattached end and the second unattached end;wherein neither unattached end is in communication with an exterior of the graft, andwherein the patch is configured to temporarily constrain a portion of a medical instrument within the passageway.2. The stent graft assembly of wherein the tubular body comprises graft material having a sidewall and a fenestration in the sidewall.3. The stent graft assembly of wherein the patch is circumferentially offset from the fenestration.4. The stent graft assembly of wherein the tubular body has a posterior side and an anterior side claim 2 , and wherein the patch extends at least partially around a circumference of the inner surface; and wherein the fenestration is on the posterior side and the patch is on the anterior side.5. The stent graft assembly of wherein the patch has at least two lateral edges and the patch is attached to the inner surface at the at least two lateral edges.6. The stent graft assembly of further comprising at least one stent ring.7. The stent graft assembly of wherein the stent is disposed at least partially over the patch and in a first configuration closes the passageway.8. The stent graft assembly of further comprising:a ...

STENT MONITORING ASSEMBLY AND METHOD OF USE THEREOF

Assemblies are provided comprising a stent and a sensor positioned on and/or in the stent. Within certain aspects the sensors are wireless sensors, and include for example one or more fluid pressure sensors, contact sensors, position sensors, accelerometers, pulse pressure sensors, blood volume sensors, blood flow sensors, blood chemistry sensors, blood metabolic sensors, mechanical stress sensors and/or temperature sensors. Within certain aspects these stents may be utilized to assist in stent placement, monitor stent function, identify complications of stent treatment, monitor physiologic parameters and/or medically image a body passageway, e.g., a vascular lumen. 189-. (canceled)90. An assembly comprising a first stent in combination with a second stent , wherein each of the first and second stents is a unitary stent; and a sensor positioned on or within each of said first and second stents , wherein the assembly further comprises an antenna for sending and receiving data.91. The assembly according to wherein the sensor is positioned on an outer wall of the first stent or on an inner wall of the first stent.92. The assembly according to wherein the sensor is positioned within the first stent material itself.93. The assembly according to wherein the sensor of the first stent is a fluid pressure sensor.94. The assembly according to wherein the sensor of the first stent is a blood volume sensor95. The assembly according to wherein the sensor of the first stent is a blood flow sensor.96. The assembly according to wherein the sensor of the first stent is a blood chemistry sensor.97. The assembly according to wherein the sensor of the first stent is a blood metabolic sensor.98. The assembly according to claim 90 , wherein the sensor of the first stent measures the development of restenosis.99. The assembly according to claim 90 , wherein the sensor of the first stent measures the development of a thrombus claim 90 , atherosclerosis claim 90 , tumor claim 90 , ...

Aneurysm Graft With Stabilization

The present invention provides methods and apparatus for the endoluminal positioning of an intraluminal prosthesis at a target location within a body lumen. The device may comprise a porous, multi-layer prosthesis that can include stabilization members for stabilizing the placement of the device at the site. Various components can have different densities or pore sizes. 1. A vascular defect treatment device , comprising:an inner tubular member sized to span a vascular defect;at least one stabilization member associated with said tubular member and disposed so as to provide support to said inner tubular member in a region of said vascular defect.24-. (canceled)5. A vascular defect treatment device according to claim 1 , wherein said at least one stabilization member comprises two stabilization members disposed opposite each other along an axis of said inner tubular member.6. A vascular defect treatment device according to claim 5 , wherein opposing ends of said two stabilization members contact each other so as to form a ring of contact around said inner tubular member.7. A vascular defect treatment device according to claim 6 , wherein said ring of contact is substantially planar and is substantially orthogonal to said axis of said inner tubular member.8. A vascular defect treatment device according to claim 6 , wherein said ring of contact is substantially planar and is at an angle to the axis of said inner tubular member.9. A vascular defect treatment device according to claim 5 , wherein opposing ends of said two stabilization members are spaced from each other so as to create an axial space around said inner tubular member.10. (canceled)11. A vascular defect treatment device according to claim 1 , wherein said at least one stabilization member comprises three stabilization members disposed axially along said axis of said inner tubular member.12. A vascular defect treatment device according to claim 11 , wherein opposing ends of said three stabilization members ...

STENT GRAFT ADAPTOR

A stent graft adaptor has an outer graft tube and an inner graft tube with the inner graft tube substantially concentric with and within the outer graft tube. A joining member extends between the inner tube and the outer tube. The joining member can be a continuous fold of graft material extending from a proximal end of the outer tube to a proximal end of the inner tube. The inner tube has at least one self expanding stent on an outer surface thereof and the outer graft tube has at least one self expanding stent on an inner surface. The outer surface of the outer tube provides a sealing surface to engage against the wall of a vessel and the inner tube provides a sealing surface to engage with a corresponding sealing surface of a stent graft deployed through it. The outer sealing surface can include barbs. 1. A stent graft delivery assembly comprising:a delivery device including a proximal end, a distal end, a nose cone dilator at the proximal end, the nose cone dilator having a proximal tip and a distal end, and an inner catheter extending from the distal end of the delivery device to at least the nose cone dilator;a stent graft mounted at least partially over the inner catheter, the stent graft comprising a tube of graft material and having a proximal end, a distal end and at least one stent attached to the tube of graft material, the tube of graft material having a proximal end, a proximal portion having a first diameter, a proximal portion inner lumen, a distal end, a distal end portion having a second diameter, and a distal portion inner lumen in fluid communication with the proximal portion inner lumen;wherein the graft material of the proximal portion is at least partially inverted into the lumen of the proximal portion to form an outer proximal tube portion and an inner proximal tube portion of graft material disposed within the outer proximal tube portion, the inner proximal tube portion having an edge disposed distal of the proximal end of the graft ...

AORTIC STENT-GRAFT

An aortic stent-graft includes a main aortic stent-graft and a plurality of branch arterial stent-grafts. The main aortic stent-graft includes a proximal segment, a depressed segment, and a distal segment; steps are provided on a top surface of the depressed segment from left to right; one or two first orifices are formed on a middle-upper part of a right side wall of the proximal segment, and one or two second orifices are formed on a right side wall of the steps; a first inner chimney stent is fixed inside the first orifice and a second inner chimney stent is fixed inside the second orifice; the first inner chimney stent is sutured along an inner wall of the proximal segment, and the second inner chimney stent is sutured along an inner wall of the steps; and one of the branch arterial stent-grafts is placed inside each inner chimney stent. 1. An aortic stent-graft , comprisinga main aortic stent-graft and a plurality of branch arterial stent-grafts,wherein at least one step is provided on a top surface of the depressed segment from left to right;', 'one or two first orifices are formed on a middle-upper part of a right side wall of the proximal segment, and one or two second orifices are formed on a right side wall of the at least one step;, 'the main aortic stent-graft comprises a proximal segment, a distal segment, and a depressed segment connecting the proximal segment and the distal segment;'} the first inner chimney stent is sutured along an inner wall of the proximal segment, and the second inner chimney stent is sutured along an inner wall of the at least one step;', 'one of the plurality of branch arterial stent-grafts is placed inside each of the first inner chimney stent and the second inner chimney stent; and', 'no orifice is formed on a left side wall of the distal segment., 'a first inner chimney stent is fixed inside each of the one or two first orifices and a second inner chimney stent is fixed inside each of the one or two second orifices;'}2. ( ...

STENT GRAFT SYSTEM AND A METHOD FOR COUPLING STENT GRAFTS AS A STENT GRAFT SYSTEM

A stent graft system () with a first stent graft () expandable in respect of a diameter, and with at least a second stent graft (). The first stent graft () at least in some areas has a tubular net structure () which, in an expanded mode, has a net structure () with substantially round annular meshes (). The at least second stent graft () has, at a distal end (), outwardly extending barbs () via which the at least second stent graft () can be coupled to the first stent graft () in the expanded mode. The distal end () of the at least second stent graft () passes through a round annular mesh () of corresponding diameter and, with its outwardly extending barbs (), engages on the round annular mesh (). Also, a method for coupling stent grafts as a stent graft system. 112324453673236575. A stent graft system () having an expandable diameter first stent graft () and at least one second stent graft () , the first stent graft () comprising , at least in regions , a tubular mesh structure () having in an expanded mode a mesh structure () with substantially circular annular loops () , the at least second stent graft () having at a distal end () outwardly projecting barbs () , via which the at least second stent graft () can be coupled to the first stent graft () in the expanded mode , wherein the at least second stent graft () pierces with the distal end () a circular , annular loop () corresponding to its own diameter and engages with the respective outwardly projecting barbs () on the circular annular loop ().2128. The stent graft system () according to claim 1 , wherein the first stent graft () is coated with a layer () claim 1 , in particular a polymer claim 1 , such as polytetrafluoroethylene (PTFE).342. The stent graft system according to claim 2 , wherein a material of the mesh structure () of the first stent graft () is a shape-memory alloy claim 2 , preferably Nitinol.4429. The stent graft system according to claim 1 , wherein the mesh structure () of the first stent ...

METHOD FOR REPLACEMENT OF HEART VALVE

A method for implanting a replacement heart valve within a diseased valve includes accessing a patient's heart by piercing a myocardium, advancing a guidewire into the patient's heart, and installing an access device in a wall of the heart. The access device preferably has at least one valve mechanism. A valve delivery device is advanced over the guidewire and through the access device. The valve delivery device has a replacement heart valve disposed along a distal end portion thereof. The replacement heart valve preferably includes an outer support structure and a leaflet valve disposed within the outer support structure. The replacement heart valve is radially expanded within the diseased valve. During implantation, the outer support structure conforms to a diameter of the diseased valve and the leaflet valve expands to a fixed size having a diameter smaller than the diameter of the diseased valve. 1. A method for implanting a replacement heart valve within a diseased valve , the method comprising:accessing a patient's heart by piercing a myocardium;advancing a guidewire into the patient's heart;installing an access device in a wall of the heart, the access device having at least one valve mechanism for preventing blood from escaping the patient's heart;advancing a valve delivery device over the guidewire and through the access device, the valve delivery device having a replacement heart valve disposed along a distal end portion thereof, the replacement heart valve including an outer support structure and a leaflet valve disposed within the outer support structure; andradially expanding the replacement heart valve in the diseased valve;wherein the outer support structure conforms to a diameter of the diseased valve and the leaflet valve expands to a fixed size with a diameter smaller than the diameter of the diseased valve.2. The method of claim 1 , wherein the leaflet valve comprises leaflets made from pericardium.3. The method of claim 2 , wherein the outer ...

DEVICE FOR ENDOVASCULAR AORTIC REPAIR AND METHOD OF USING THE SAME

An intraluminal vascular prosthesis assembly, having a hollow cylindrical body with a first end and a second end is provided. The assembly includes, at its first end, a first vascular prosthesis portion, and at its second end, a second vascular prosthesis portion which has only a prosthesis material. The vascular prosthesis assembly has a stent portion which is provided between the first vascular prosthesis portion and the second vascular prosthesis portion, the stent portion being free of prosthesis material to allow fluid flow therethrough and received within the aortic arch and spanning the brachiocephalic artery, left common carotid artery, and left subclavian artery when placed within the aortic arch of a patient. 1. An intraluminal vascular prosthesis assembly, having a hollow cylindrical body with a first end and a second end. This application is a continuation of U.S. patent application Ser. No. 16/042,286 entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which was filed on Jul. 23, 2018, which is a continuation of U.S. patent application Ser. No. 14/614,628 entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which was filed on Feb. 5, 2015, which is a continuation of U.S. patent application Ser. No. 14/569,306 entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which was filed on Dec. 12, 2014, which is a divisional of U.S. patent application Ser. No. 13/706,896, entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which claims the benefit under 35 U.S.C. § 119 to U.S. Provisional Application Ser. No. 61/567,458 entitled “Transcathetar Aortic Valve for Endovascular Aortic Repair,” which was filed on Dec. 6, 2011. Application Ser. No. 13/706,896 also claims priority under § 119 to U.S. Provisional Application Ser. No. 61/723,446 entitled “Transcathetar Aortic Valve for Endovascular Aortic Repair,” which was filed on Nov. 7, 2012. Each of the ...

ALIGNMENT SYSTEM FOR MULTIPLE BRANCH ENDOGRAFTS

A nonmodular endograft system for treating aortic aneurysms involving bilateral renal arteries can include a main fabric cover that is sealed, coupled, or integral, with first and second branch fabric covers. The system can be configured so that after the main cover is expanded in the aorta, and after the two branch covers are respectively expanded in the renal arteries such that (i) the first cover ostium is substantially aligned with the first renal ostium, and (ii) the second cover ostium is not substantially aligned with the second renal ostium, then aortic blood flows from the main cover into each of the branch covers. 1. A method for placing an endograft assembly in an aorta having branching vessels , said method comprising:providing an endograft including a main cover, a first branch cover, and a second branch cover;implanting the endograft in the aorta between opposed branching vessels or covering adjacent branching vessels, wherein the first branch cover and the second branch cover move relatively freely axially, radially, and rotationally relative to a long axis of the main cover to accommodate different positions of the branching vessels.2. A method as in claim 1 , wherein the main cover expands in the aorta to contact a wall of the aorta.3. A method as in claim 2 , wherein the main cover further expands to contact a wall of the at least one of the first and second branching vessels.4. A method as in claim 3 , wherein the main cover further expands to contact the walls of both branching vessels.5. A method as in claim 1 , wherein each branch cover is tapered from a wide cross-section at its base where connected to the main cover to a narrower cross-section along more distal portions thereof.6. A method as in claim 1 , wherein each branch cover is integrally formed with the main cover.7. A method as in claim 1 , wherein each branch cover and the main cover comprise a fabric.8. A method as in claim 1 , further comprising expanding a main stent within a ...

MODULAR MULTIBRANCH STENT ASSEMBLY AND METHOD

The techniques of this disclosure generally relate to a modular stent device including a main body configured to be deployed in the ascending aorta, a bypass gate configured to be deployed in the aorta, and a bifurcated contra limb. The bifurcated contra limb includes a single proximal limb that is bifurcated (split) into a first distal limb and a second distal limb. By forming the bifurcated contra limb to include a single proximal limb that is bifurcated into the distal limbs, guiding a guide wire into the relatively larger opening of bifurcated contra limb at a proximal end is simpler than guiding a guidewire into two smaller limbs extending distally from main body. Accordingly, cannulation of the bifurcated contra limb is relatively simple thus simplifying the procedure. In addition, the parallel design mimics anatomical blood vessel bifurcations to limit flow disruptions. 1. An assembly comprising: a main body configured to be deployed in the ascending aorta;', 'a bypass gate configured to be deployed in the aorta; and', a proximal limb extending from the main body;', 'a first distal limb extending from the proximal limb; and', 'a second distal limb extending from the proximal limb, wherein the first distal limb is connected to the second distal limb at a septum., 'a bifurcated contra limb comprising], 'a first modular stent device comprising2. The assembly of wherein the bifurcated contra limb is bifurcated from a single proximal opening to two distal openings.3. The assembly of wherein the proximal limb is bifurcated into the first distal limb and the second distal limb.4. The assembly of wherein the bifurcated contra limb further comprises a transition region where the proximal limb is bifurcated into the first distal limb and the second distal limb.5. The assembly of wherein the proximal limb extends distally from a proximal end of the bifurcated contra limb to the transition region and comprises a single lumen.6. The assembly of wherein:the first distal ...

Endovascular graft having a cannulation pocket

A stent graft for placement in a lumen of a patient is disclosed. The stent graft comprises: a main tubular body of a biocompatible graft material having a main lumen, the main tubular body having a proximal end and a distal end; a side arm extending from the main tubular body, the side arm having a side arm lumen, the side arm lumen being in fluid communication with the main lumen through a side arm opening in the main tubular body; and a cannulation pocket. The pocket comprises: an exit aperture positioned opposite the side arm opening; an entry aperture longitudinally spaced from the entry aperture in a direction toward the distal end of the main tubular body; and a wall, the wall laterally spaced from the main lumen so as to provide a guide surface for a cannula fed through the entry aperture.

STENT FOR BIFURCATION, A SYSTEM FOR INTRAVASCULAR IMPLANTATION OF THE STENT FOR BIFURCATION AND A METHOD OF IMPLANTATION OF THE STENT FOR BIFURCATION

A stent for bifurcation, including two cylindrical parts: a distal part () of smaller diameter and a proximal part () of greater diameter, connected by two arranged as opposite longitudinal connectors () having length (L) of 0.5 to 8 mm and forming a cell of the stent having an enlarged surface area (), the connectors having a curvilinear shape, in particular a sinusoidal shape. A method of introducing the stent and a system for intravascular implantation are disclosed. 1. A system for intravascular implantation of the stent for bifurcation , comprising the proximal part and the distal part including an external tube , an internal tube and a profiled balloon , wherein in the distal part of the system , on the internal tube marked with three rings , visible at X-rays , there is the profiled balloon fastened with the proximal part to the external surface of the external tube and with the distal part to the external surface of the internal tube , and the stent for bifurcation comprising two cylindrical parts: the distal part of smaller diameter and the proximal part of greater diameter , connected by two longitudinal connectors arranged as opposite having length of 0.5 to 8 mm and forming a cell of the stent having an enlarged surface area , the connectors having a curvilinear shape , is clamped on the profiled balloon in a detachable way , the profiled balloon comprising three non-separable parts , the distal part , of smaller diameter , the proximal part , of greater diameter , and the medial part having length from 0.5 to 8 mm , located between the distal part and the proximal part , a position of the ring coinciding with the proximal edge of the distal part of the stent clamped on the balloon.2. A system of claim 1 , wherein a ratio of the distal part diameter to the proximal part diameter of the profiled balloon is within the limits of 1.0: 1.1 to 1.0: 2.0.3. A system of claim 1 , wherein between long edges of the distal part of the profiled balloon and an edge of ...

Vascular prosthesis for treating aneurysms

Apparatus for use with a delivery catheter, including a primary stent-graft and a flared endovascular stent-graft, which is configured to initially be positioned in the delivery catheter in a radially-compressed state, and to assume a radially-expanded state upon being deployed from the delivery catheter. The primary stent-graft includes (a) a structural member, which includes a plurality of structural stent elements, and which, when the flared endovascular stent-graft assumes the radially-expanded state, is shaped so as to define a flared caudal portion, which flares radially outward in a caudal direction; (b) at least one biologically-compatible substantially fluid-impervious flexible sheet, which is coupled to at least the flared caudal portion; and (c) a stent-engagement member, which is generally tubular when the flared endovascular stent-graft assumes the radially-expanded state, which is disposed at least partially within the flared caudal portion, and which is configured to be sealingly coupled to the primary stent-graft.

ORIENTABLE IMPLANTABLE DEVICE AND METHOD

An intravascular system having a first catheter having a first non-circular transverse cross-sectional configuration and a first delivery device configured for insertion into the lumen of the catheter. The first delivery device includes an implantable medical device and an elongated member supporting the first medical device such that the first elongated member and the first medical device are movable through the lumen of the first catheter. The first elongated member has a second non-circular transverse cross-sectional configuration corresponding to the first non-circular transverse cross-sectional configuration to thereby inhibit rotation of the first elongated member within the catheter and control orientation of the first medical device relative to the catheter. 1. An intravascular system for treating a blood vessel , the intravascular system comprising:a first catheter defining a first lumen terminating in a distal end hole, the first lumen having a first non-circular transverse cross-sectional configuration; and a first implantable medical device; and', 'a first elongated member supporting the first medical device such that the first elongated member and the first medical device are movable through the first lumen to facilitate delivery of the first medical device to a target location within the blood vessel, the first elongated member having a second non-circular transverse cross-sectional configuration corresponding to the first non-circular transverse cross-sectional configuration to thereby inhibit rotation of the first elongated member within the catheter and control orientation of the first medical device relative to the catheter., 'a first delivery device configured for insertion into the first lumen of the catheter, the first delivery device including2. The intravascular system of claim 1 , wherein the first catheter has a hub and at least one of the hub claim 1 , first catheter claim 1 , first elongated member claim 1 , and medical device has at least ...

MODULAR MULTIBRANCH STENT ASSEMBLY AND METHOD

The techniques of this disclosure generally relate to an assembly including a single branch stent device and a modular stent device configured to be coupled to the single branch stent device. The single branch stent device includes a main body and a branch coupling extending radially from the main body. The modular stent device includes a main body configured to be coupled inside of the main body of the single branch stent device, a bypass gate extending distally from a distal end of the main body of the modular stent device, and an artery leg extending distally from the distal end of the main body of the modular stent device. 1. A method comprising:introducing a single branch stent device via femoral access;advancing the single branch stent device into the ascending aorta;deploying the single branch stent device such that a main body of the single branch stent device engages the aorta and a branch coupling perfuses the brachiocephalic artery;introducing a modular stent device via supra aortic access through an artery distal of the brachiocephalic artery;advancing the modular stent device such that a main body of the modular stent device is located within the main body of the single branch stent device; anddeploying the modular stent device such that the main body of the modular stent device engages the main body of the single branch stent device, a bypass gate of the modular stent device engages the aorta, and an artery branch of the modular stent device is located within the artery distal of the brachiocephalic artery.2. The method of further comprising deploying a bridging stent graft within the branch coupling and the brachiocephalic artery.3. The method of wherein the artery distal of the brachiocephalic artery is selected from the group consisting of the left common carotid artery and the left subclavian artery.4. A method comprising:introducing a single branch stent device via femoral access;advancing the single branch stent device into the ascending aorta; ...

Methods, systems, and devices for relieving congestion of the lymphatic system

Systems, devices and methods for treating lymphatic congestion are disclosed. In one method, a balloon is placed at or near the veno-lymph junction. The balloon is inflated and deflation through cycles of slow inflation and rapid deflation. In another embodiment, an arteriovenous fistula is created near the veno-lymph junction. Alternate embodiments may also include axial pumps, stents, or balloons in combination with the fistula. These devices and methods create an acceleration of the blood flow past the lymphatic duct which reduces local pressure via the Venturi effect and according to the Bernoulli principle which facilitates lymph entering into the bloodstream.

Implanted Extracardiac Device for Circulatory Assistance

This invention is an implanted extracardiac device for supplementing blood circulation which comprises an implanted blood flow lumen, a blood flow increasing mechanism, and a control unit. Its design improves blood circulation when the blood flow increasing mechanism is operating, without hindering native blood flow when the mechanism is not operating. This device improves circulation without intruding on cardiac tissue or weakening the heart by completely supplanting cardiac function. Also, since the device allows native blood flow when the blood flow increasing mechanism is not in operation, it requires less power and can enable more patient mobility. 1. An implanted extracardiac device for supplementing blood circulation comprising:at least one implanted blood flow lumen, wherein this implanted blood flow lumen is configured to be implanted within a person's body so as to receive blood inflow from a blood vessel at an upstream location with respect to the natural direction of blood flow, wherein this implanted blood flow lumen is configured to discharge blood into a blood vessel at a downstream location with respect to the natural direction of blood flow, wherein this implanted blood flow lumen has a longitudinal axis spanning from the upstream location to the downstream location, wherein this implanted blood flow lumen has a cross-sectional area through which blood can flow which is substantially perpendicular to the longitudinal axis, and wherein a minimum cross-sectional flow area is defined as the minimum unobstructed cross-sectional area through which can blood flow from the upstream location to the downstream location;a blood flow increasing mechanism, wherein this blood flow increasing mechanism is configured to be implanted within a person's body, wherein this blood flow increasing mechanism is configured to increase the flow of blood from the upstream location to the downstream location when the blood flow increasing mechanism is in operation by ...

Prosthesis having pivoting fenestration

The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, and a second perimeter attached to and surrounding the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape. In one aspect, the prosthesis includes at least three pivotable fenestrations,

BIFURCATED HIGHLY CONFORMABLE MEDICAL DEVICE BRANCH ACCESS

The present invention comprises a highly conformable stent graft with an optional portal for a side branch device. Said stent graft comprises a graft being supported by a stent, wherein said stent comprises undulations each which comprise apices in opposing first and second directions and a tape member attached to said stent and to said graft such that the tape member edge is aligned to the edge of the apices in the first direction of the each of the undulations, thus confining the apices in the first direction of the undulations to the graft and wherein the apices in the second direction of the undulation are not confined relative to the graft; wherein said graft forms unidirectional pleats where longitudinally compressed and wherein said apices in the first direction of said undulation is positioned under an adjacent pleat when compressed. The invention also discloses and claims methods of making and using said highly conformable stent graft and method of making the optional portal. 1. A stent graft comprising:a graft having an inward-facing surface and an outward-facing surface;a stent having undulations defining apices that extend in opposing first and second directions; anda tape member extending helically about and being fixedly secured to the graft such that a portion of the tape member covers the apices of the stent to form a series of confined apices in the first direction and a series of unconfined apices in the second direction, whereby the stent graft is configured to be longitudinally compressed to form circumferentially oriented unidirectional pleats along one of the inward-facing and outward-facing surfaces of the graft with the confined apices positioned under an adjacent pleat.2. The stent graft of claim 1 , wherein the tape member is bonded at least in part to the stent by the adhesive.3. The stent graft of claim 1 , wherein thee portion of the tape member in each row substantially covers the apices of the stent in an adjacent row thereby forming ...

ELECTROMAGNETIC SYSTEM FOR RAPID CANNULATION OF FENESTRATED ENDOVASCULAR GRAFTS

Disclosed are implantable tubular devices having a fenestration in a wall of the tubular device and a conductive coil positioned around the fenestration, such that the coil is operable to generate a magnetic field when electrical current flows through the coil. The magnetic field can be used to draw a ferrous or magnetically tipped guidewire or other device to and through the fenestration. In the example of a fenestrated endovascular graft, the coil can be used to draw a guidewire out through a fenestration into a branch blood vessel, such that the guidewire can be used to deliver a branch of the graft through the fenestration into the branch vessel. A power source can be contained in a nosecone. 1. An apparatus comprising:a tubular body configured to be implanted within a patient;a fenestration in a wall of the tubular body; anda coil positioned around the fenestration, the coil comprising a permanent magnet or being operable to generate a magnetic field when electrical current flows through the coil, such that the coil is operable to magnetically guide another device to or through the fenestration.2. The apparatus of claim 1 , wherein the tubular body comprises a graft.3. The apparatus of claim 1 , wherein the tubular body comprises a stent.4. The apparatus of claim 1 , wherein the tubular body is configured to be implanted within a blood vessel to treat an aneurysm or injury of the blood vessel.5. The apparatus of claim 1 , wherein the apparatus comprises an endovascular graft and is configured to be implanted within a blood vessel.6. The apparatus of claim 1 , wherein the fenestration is positioned to align with a branch vessel so that fluid can flow between the tubular body and the branch vessel through the fenestration.7. The apparatus of claim 1 , wherein the coil is operable to generate a magnetic field that is sufficient to draw a guidewire or other transvascular device to the fenestration from within the tubular body.8. The apparatus of claim 1 , wherein ...

Vessel Access Catheter

The described invention provides an endovascular device comprising a tube comprising a first end comprising a bifurcation and a second end comprising an opening. The bifurcation at the first end comprises a first branch and a second branch. The opening at the second end comprises a primary opening and a secondary opening. The first branch and the primary opening form a working lumen. The second branch and the secondary opening form a support lumen. The described invention further provides an endovascular device comprising a tube comprising a side-hole, a first segment comprising a primary opening and a second segment. The side-hole and the first segment form a working lumen. The second segment forms a support lumen. 1) An endovascular device comprising:a tube comprising:a) a side-hole;b) a first segment comprising a primary opening; andc) a second segment comprising an end that in cross-section is circular, the side hole divides the endovascular device into the first segment and the second segment;', 'the first segment extends from the primary opening to the side-hole and', 'the second segment extends from the side-hole and tapers to the end hole,', 'the side-hole and the first segment form a working lumen, and', 'the second segment forms a support lumen, wherein the support lumen is effective:', 'i) to provide stability to the working lumen of the endovascular device; and', 'ii) to anchor the endovascular device within a blood vessel;', 'iii) to prevent catheter coil prolapse due to a counterforce against the endovascular device by a second device being delivered through the endovascular device to a more distal location or by a prolapsed coil tail of the endovascular device; and', 'iv) to facilitate placement of the second endovascular devices distally., 'wherein'}2) The endovascular device according to claim 1 , wherein the second device comprises a catheter claim 1 , a therapeutic balloon claim 1 , a therapeutic stent claim 1 , or another endovascular device.3) ...

FENESTRATION TEMPLATE FOR ENDOVASCULAR REPAIR OF AORTIC ANEURYSMS

To provide simple yet accurate stent graft fenestration, a patient-specific fenestration template is used as a guide for graft fenestration. To generate the fenestration template, a patient's medical imaging data such as CT scan data may be used to generate a 3-D digital model of an aorta lumen of the patient. The aorta lumen may encompass one or more branch vessels, which may be indicated on the 3-D digital model. Based on the 3-D digital model or a segment thereof, the fenestration template may be generated, for example, using 3-D printing technology. The fenestration template may include one or more holes or openings that correspond to the one or more branch vessels. To fenestrate a stent graft, the fenestration template is coupled to the stent graft so that the holes or openings on the fenestration template indicate the fenestration locations. 1. A fenestration template device for an aortic graft , comprising:a physical model representing a section of a patient's aorta having one or more branch vessel openings, the physical model comprising a wall defining a lumen and having one or more openings in the wall representing the one or more branch vessel openings of the patient's aorta.2. The device of claim 1 , wherein the physical model is generated using a three-dimensional (3-D) printing technology.3. The device of claim 1 , wherein the physical model is generated based at least in part on a 3-D digital model of the patient's aorta.4. The device of claim 1 , wherein the one or more openings in the wall are indicative of locations of one or more fenestrations on the stent graft when the fenestration template device is coupled with the aortic graft.5. The device of claim 1 , wherein the physical model is disposable.6. A method for fenestrating a stent graft to be used in treating a patient claim 1 , comprising:obtaining a fenestration template generated based at least in part on a 3-D digital model of an aorta lumen of the patient, the fenestration template ...

ENDOGRAFT WITH ONE OR MORE APERTURES

The present embodiments describe an endograft having one or more apertures, and methods for constructing the same. In one example, an endograft comprises a proximal region having a proximal opening, and a distal region having first and second apertures separated by a partition. A body portion having a lumen is disposed between the proximal region and distal region, and has a central longitudinal axis. At least one of the first and second apertures is oriented oblique to the central longitudinal axis. 1. An endograft , comprising:a proximal region having a proximal opening;a distal region having first and second apertures separated by a partition;a body portion having a lumen disposed between the proximal region and distal region, and having a central longitudinal axis,wherein at least one of the first and second apertures is oriented oblique to the central longitudinal axis.2. The endograft of claim 1 , wherein each of the first and second apertures are oriented oblique to the central longitudinal axis.3. The endograft of claim 1 , wherein the partition is distal to the first and second apertures.4. The endograft of claim 1 , wherein the first and second apertures are on opposite sides of the distal region.5. The endograft of claim 1 , wherein the partition and the body portion are made of the same graft material.6. The endograft of claim 1 , wherein the partition further comprises stitches disposed between the first and second apertures.7. The endograft of claim 1 , further comprising an attachment stent coupled to the proximal region and extending proximally from the proximal opening.8. The endograft of claim 1 , wherein the distal region is coupled to the body portion via stitching.9. The endograft of claim 1 , wherein the body portion has one or more fenestrations.10. The endograft of claim 1 , further comprising a first extension limb extending distally from the first aperture and sealably engaged to the first aperture claim 1 , wherein the first extension limb ...

VASCULAR ENDOGRAFT

An endograft includes a main body having a wall separating interior and exterior surfaces and adapted to be inserted within the vessel. The main body is characterized by a single proximal opening and two distal openings and at least one aperture extending through the wall. At least one stent is secured to the main body that upon expansion pressure fits the main body into the vessel. An open tunnel is secured to the interior surface of the main body around the main body aperture and secured somewhere along the tunnel length to provide fluid communication between the interior and exterior surfaces of the main body through the aperture and with the vascular branch in proximity to the main body aperture. The insertion of a sleeve positioned partly within the tunnel and extending beyond the exterior surface of the main body into the vascular branch assures to the vascular branch. 1. An endograft for a vessel , said endograft comprising:a main body having a wall, the wall defining an internal surface and an exterior surface, where said main body is adapted to be placed within the vessel, the wall defining a single lumen at a proximal end and a distal end, and a set of four main body apertures extending from the interior surface to the exterior surface above the distal end that each correspond to a separate vascular branch;at least one expandable stent secured to the distal end;a set of four tunnels, where each of the four tunnels have a circumference, a length extending between a mouth and a terminus and sealed to the interior surface of said main body about the main body aperture, each of said four tunnels secured to the internal surface to provide fluid communication between the interior surface and the exterior surface through the four main body apertures that align with each of the separate vascular branches in proximity to each of the four main body apertures and where said four tunnels do not extend beyond the dimensions of the main body;a sleeve positioned partly ...

Side branch balloon

An improved balloon catheter structure includes a beveled distal tip, a reinforced distal portion, and an elastic or split sleeve over at least a portion of the balloon. The balloon may have a short length and a marker at its midline. The catheters are particularly useful for crossing through stent walls at vessel bifurcations.

STENT GRAFT AND USE METHOD THEREFOR

A stent, comprising a frame and a skirt () that covers the frame, wherein the stent comprises an axial opening () that penetrates the frame and the skirt (). 140. A stent , comprising a frame and a skirt () covering said frame , wherein:{'b': ['22', '40'], '#text': 'said stent comprises an axial opening () penetrating through said frame and skirt ().'}222. The stent of claim 1 , wherein said axial opening () is selected from rectilinear claim 1 , arc-shaped or window-shaped openings.3. The stent of claim 1 , further comprising a fenestration or a branch stent corresponding to a bifurcation position of blood vessel.422. The stent of claim 1 , wherein the frame at said axial opening () portion is selected from an open-loop frame claim 1 , no frame claim 1 , or a frame with a double-ring structure.523242324. The stent of claim 4 , wherein said double-ring structure comprises an inner ring () and an outer ring () claim 4 , said inner ring () and outer ring () can move relative to each other.62241. The stent of claim 1 , wherein said axial opening () has an edge that further comprises a second skirt component ().7. The stent of claim 1 , wherein said frame is composed of wave-shaped or grid-like structures of equal or different spacing.8. The stent of claim 7 , wherein said material is selected from stainless steel claim 7 , nickel-titanium memory alloy or cobalt-chromium alloy.91232. The stent of claim 1 , wherein said stent has a distal end and a proximal end claim 1 , said stent further comprises an end skirt ( claim 1 , ) located at the distal end or proximal end of said stent.10. The stent of claim 1 , wherein said stent has a straight-tube shape claim 1 , a tapered shape or a partially curved shape.1121122. The stent of claim 1 , further comprising a closing mechanism () for closing said axial opening ().12211. The stent of claim 11 , wherein said closing mechanism () is selected from the group consisting of sutures claim 11 , interlocking structure claim 11 , ...

Improved endoprosthesis and catheter

A stent is provided comprising a tubular body formed by a polymer layer of expanded polytetrafluoroethylene and a layer made of alloy and comprising two open ends, at least one anterior side wall opening acting as an aperture allowing puncture by a needle, the side wall opening being at a predetermined distance from each of the ends and being formed in the alloy layer to allow a needle to penetrate inside the tubular body. The exact position of the anterior side wall opening within a body cavity can be identified by radiopaque markers, and the inherent nature of the expanded polytetrafluoroethylene allows puncture by a needle when it is desired to unplug a blocked or partially-blocked stent.

AUTOMATED RETRIEVABLE HEMORRHAGE CONTROL SYSTEM

Some implementations of an endovascular device include a stent graft with an expandable tubular metallic frame and a covering material disposed on at least a portion of the metallic frame. The stent graft defines a lumen therethrough. In a particular embodiment, a first balloon is disposed around an outer periphery of the stent graft, a second balloon is disposed around the outer periphery of the stent graft and spaced apart from the first balloon, and a third balloon is disposed within the stent graft lumen between the first balloon and the second balloon. The third balloon can be inflated to fully or partially occlude the lumen. The first and second balloons can be individually inflated to fully or partially shunt blood flow from a blood vessel through the stent graft. In some embodiments, sensors and an automated control unit are included to automate the operations of the endovascular device. 1. An endovascular device comprising:a stent graft comprising an expandable tubular metallic frame and a covering material disposed on at least a portion of the metallic frame, the stent graft defining a lumen that extends between a first end of the stent graft and a second end of the stent graft;a first balloon disposed around an outer periphery of the stent graft;a second balloon disposed around the outer periphery of the stent graft and spaced apart from the first balloon; anda third balloon disposed within the lumen at a location along the stent graft between the first balloon and the second balloon, the third balloon having a fully inflated configuration that fully occludes the lumen and a partially inflated configuration that partially occludes the lumen for modulating blood flow through the stent graft.2. The endovascular device of claim 1 , wherein the first balloon fully surrounds the outer periphery of the stent graft claim 1 , and wherein the second balloon fully surrounds the outer periphery of the stent graft.3. (canceled)4. (canceled)5. The endovascular device ...

Assembly of stent grafts with diameter reducing ties

A temporary diameter reduction constraint arrangement for a stent graft is disclosed. The arrangement comprises: primary and secondary release wires extending along the graft; a plurality of loops of thread, each loop engaged with either the primary or secondary wire and engaged around a portion of the graft circumferentially spaced away from its release wire, and drawn tight to reduce the diameter of the graft; an end constraint arrangement comprising four of the plurality of loops of thread arranged into a first and second pairs engaged with respective primary and secondary wires; and an intermediate constraint arrangement comprising a fifth and sixth of the plurality of loops of thread arranged into a third pair, the third pair engaged with the primary release wire, the primary release wire deviating towards the secondary release wire so as to locate the intermediate constraint arrangement substantially in-line with the end constraint arrangement.

Temporary diameter reduction constraint arrangement for a stent graft in combination with a stent graft

A temporary diameter reduction constraint arrangement for a stent graft in combination with a stent graft is disclosed. The stent graft has a proximal end and a distal end and comprises a biocompatible graft material tube and a plurality of longitudinally spaced apart self-expanding stents fastened thereto, including at least an end stent and a plurality of intermediate stents. The constraint arrangement comprises: an elongate receiver extending longitudinally within the graft material tube; a first wire extending longitudinally along the graft material tube in a first serpentine pattern; and a second wire extending longitudinally along the graft material tube in a second serpentine pattern, wherein at least one of the first and second wires repeatedly loops over the receiver along a longitudinal length of the stent graft thereby securing the stent graft to the receiver. In one embodiment there is also a plurality of loops of thread to reduce the stent graft.

TOTAL ARCH CONCEPT

Various aspects of the present disclosure are directed toward prosthesis that may include a first graft component and a second graft component coupled to the first graft component. The prosthesis may also include a gap or a space between the first graft component and the second graft component. 1. A prosthesis comprising:a first graft component;a second graft component arranged within the first graft component and coupled thereto, the second graft component having a dog bone shape;a gap arranged between the first graft component and the second graft component; anda stent structure arranged with the first graft component.2. The prosthesis of claim 1 , wherein the first graft component comprises an interior surface and an exterior surface claim 1 , end portions of the interior surface of the first graft component being attached to end portions of the second graft component claim 1 , and the stent structure is attached to the exterior surface of the first graft component.3. The prosthesis of claim 2 , wherein the first graft component is configured to stretch in response to a force applied to at least one of the first graft component claim 2 , the second graft component claim 2 , and the stent structure.4. The prosthesis of claim 3 , wherein the first graft component is configured to maintain the gap between the first graft component and the second graft component in response to the force applied to at least one of the first graft component claim 3 , the second graft component claim 3 , and the stent structure.5. The prosthesis of claim 1 , wherein the first graft component is configured to mitigate against the stent structure contacting the second graft component.6. The prosthesis of claim 1 , wherein the first graft component is configured to stretch in response to a pressure claim 1 , and the pressure originates from at least one of: within the second graft component claim 1 , between the first graft component and the second graft component claim 1 , and external to ...

ENDOVASCULAR STENT-GRAFT WITH FATIGUE-RESISTANT LATERAL TUBE

A stent-graft () comprises strut members () and a graft member (), which is fixed to the strut members (). The strut members () and the graft member () are arranged so as to define, when the stent-graft () is in a radially-expanded state: a main tube (), which is shaped so as to define a main lumen (); and a lateral tube (), which (a) has (i) a distal end () and (ii) a proximal end () that is joined to a lateral wall () of the main tube () at a junction (), (b) is shaped so as to define a lateral lumen () that is in fluid communication with the main lumen (), and (c) defines a central longitudinal axis (). The strut members () that define the lateral tube () are shaped so as to define two to four non-contiguous arcuate members (), which (a) are centered around the central longitudinal axis (); and (b) collectively subtend at least 150 degrees around the central longitudinal axis (). 1. Apparatus comprising an endovascular stent-graft , which is configured to transition from a radially-compressed delivery state to a radially-expanded state , and which comprises:a plurality of structural strut members; anda graft member, which comprises one or more substantially blood-impervious flexible sheets, and which is fixed to the structural strut members, a main tube, which is shaped so as to define a main lumen, and', 'a lateral tube, which (a) has (i) a distal end and (ii) a proximal end that is joined to a lateral wall of the main tube at a junction, (b) is shaped so as to define a lateral lumen that is in fluid communication with the main lumen, and (c) defines a central longitudinal axis, and, 'wherein the structural strut members and the graft member are arranged so as to define, when the stent-graft is in the radially-expanded statewherein, when the stent-graft is in the radially-expanded state, the structural strut members that define the lateral tube are shaped so as to define two to four non-contiguous arcuate members, which (a) are centered around the central ...

MULTI-COMPONENT STENT-GRAFT SYSTEM FOR IMPLANTATION IN A BLOOD VESSEL WITH MULTIPLE BRANCHES

A multi-component stent-graft system () comprises first, second, and third generally tubular stent-grafts (), which are configured to assume radially-expanded states. The first stent-graft () is shaped so as to define a first lateral opening () when in its radially-expanded state. The second stent-graft () is shaped so as to define a second lateral opening () when in its radially-expanded state. The first and second stent-grafts () are configured such that the second stent-graft () forms a blood-impervious seal with the first stent-graft () around the first lateral opening () when the second stent-graft () is disposed therethrough, and the first and the second stent-grafts () are in their radially-expanded states. The second and the third stent-grafts () are configured such that the third stent-graft () forms a blood-impervious seal with the second stent-graft () around the second lateral opening () when the third stent-graft () is disposed therethrough, and the second and third stent-grafts () are in their radially-expanded states. Other embodiments are also described. 1. Apparatus comprising a multi-component stent-graft system , which comprises:a first generally tubular stent-graft, which is shaped so as to define a first lateral opening when in a radially-expanded state;a second generally tubular stent-graft, which is shaped so as to define a second lateral opening when in a radially-expanded state, wherein the first and second stent-grafts are configured such that the second stent-graft forms a blood-impervious seal with the first stent-graft around the first lateral opening when the second stent-graft is disposed therethrough, and the first and the second stent-grafts are in their radially-expanded states; anda third generally tubular stent-graft, which is configured to assume a radially-expanded state, wherein the second and the third stent-grafts are configured such that the third stent-graft forms a blood-impervious seal with the second stent-graft around ...

ENDOLUMINAL PROSTHESIS

An endoluminal prosthesis with a main tubular body and an auxiliary body surrounding the main tubular body to create a cavity between the main tubular body and the auxiliary body. At least one dividing wall attached to the main tubular body and the auxiliary body divides the cavity into at least two chambers, one of which has an outlet opening to the exterior of the prosthesis. Each chamber is in fluid communication with the main tubular body through fenestrations in the main tubular body and with each other. 1. An endoluminal prosthesis comprising:a tubular main body comprising a proximal end opening, a distal end opening, a main lumen extending between the proximal end opening and the distal end opening, a sidewall, a first fenestration in the sidewall, and a second fenestration in the sidewall positioned distal of the first fenestration; anda tubular auxiliary body disposed about the main body and comprising a sidewall, an outlet opening in the sidewall, a first end attached to the main body proximal of the first fenestration, a second end attached to the main body distal of the second fenestration, and a first dividing wall attached to the sidewall of the main body and the sidewall of the auxiliary body and extending longitudinally at least partially between the first end of the auxiliary body and the second end of the auxiliary body;wherein a cavity is disposed between the sidewall of the main body and the sidewall of the auxiliary body and comprises a first chamber and a second chamber disposed on opposite sides of the dividing wall and in fluid communication with one another through an opening in the dividing wall, the main lumen is in fluid communication with the first chamber through the first fenestration, the main lumen is in fluid communication with the second chamber through the second fenestration, and the first chamber is in fluid communication with a point external of the prosthesis through the outlet opening of the auxiliary body.2. The prosthesis ...

ENDOVASCULAR STENT GRAFT HAVING AN OBLIQUE FEATURE

An endovascular stent graft having an oblique feature. The endovascular stent graft may include a body having a body proximal end and a body oblique perimeter distal end oblique to the body. The endovascular stent graft may further have a leg having a leg oblique proximal end oblique to the leg and a leg distal end. The endovascular stent graft may further include a plurality of stiches coupling the body oblique perimeter distal end and the leg oblique proximal end. 1. An endovascular stent graft comprising:a body having a body proximal end and a body oblique perimeter distal end oblique to the body;a leg having a leg oblique proximal end oblique to the leg and a leg distal end; anda plurality of stitches coupling the body oblique perimeter distal end and the leg oblique proximal end.2. The endovascular stent graft of claim 1 , wherein the body is an unbranched main body.3. The endovascular stent graft of claim 1 , further comprising first and second tributary legs and a second plurality of stitches claim 1 , wherein at least one of the first and second tributary legs has a tributary leg oblique proximal end oblique to the respective tributary leg and coupled to the leg distal end via the second plurality of stitches.4. The endovascular stent graft of claim 1 , wherein the plurality of stitches coupling the body oblique perimeter distal end and the leg oblique proximal end extends along a stitch path oblique to the body and the leg.5. An endovascular stent graft comprising:a body having a body proximal end and a body distal end, the body distal end having a body distal end oblique portion and a body distal end second portion;a first leg having a first leg oblique proximal end oblique to the first leg and a first leg distal end;a second leg having a second leg proximal end and a second leg distal end;a first plurality of stitches coupling the body distal end oblique portion to the first leg oblique proximal end; anda second plurality of stitches coupling the body ...

Vascular Medical Device, System And Method

The present application discloses a covered stent and a method for navigating the covered stent to a branch vessel, the covered stent including a main body and at least one lateral side branch connected to the main body. A system of covered stents and a method for implanting, including interconnecting the covered stents is also disclosed. 1. A covered stent comprising:a main body,at least one branch, including one, two or three branches, connected to the main body, and characterized byat least one bendable and/or flexible guiding element being distally permanently or releasably attached to an interior of one of said at least one said branches at a connection point at a distal orifice of said branch, and said guiding element being proximally arranged in the interior, through and along a proximal portion of said main body and extending proximally through a proximal opening of the main body or through a leg of said covered stent, said guiding element being arranged to be received by a guiding mate of a delivery catheter for delivery of a further element such as a further covered stent to said one of said at least one said branches at said connection point, and said guiding element being configured for guiding said delivery catheter over said guiding element through said main body towards said distal orifice of said branch.2. The covered stent of claim 1 , including a fiducial marker at said connection point and/or at said distal orifice of said lateral side branch.3. The covered stent according to claim 1 , wherein the lateral side branch is laterally extendable and/or collapsible from or towards the main body.4. The covered stent according to claim 1 , wherein the side branch comprises a covered stent claim 1 , wherein the lateral side branch is integral with the main body claim 1 , and a stent portion of said covered stent is a spring claim 1 , such as a helically coiled wire claim 1 , elastically self deploying in the longitudinal direction of the side branch ...

Side branch stent graft

A joining arrangement between a main tube ( 3 ) and a side arm ( 5 ) in a side arm stent graft ( 1 ). The side arm ( 5 ) is stitched into an aperture ( 11 ) in the main tube and is in fluid communication with it. The aperture is triangular, elliptical or rectangular and the side arm is cut off at an angle to leave an end portion having a circumferential length equal to the circumference of the aperture. The side arm can also include a connection socket ( 76 ) comprising a first resilient ring ( 79 ) around the arm at its end, a second resilient ring ( 80 ) spaced apart along the arm from the first ring and a zig zag resilient stent ( 82 ) between the first and second rings. The zig-zag resilient stent can be a compression stent. Both the main tube and the side arm are formed from seamless tubular biocompatible graft material.

MODULAR BRANCHED ENDOPROSTHETIC SYSTEMS, DEVICES, AND METHODS

Devices, systems and methods of endoluminally delivering a modular endoprosthetic system in accordance with various embodiments are disclosed herein for treating disease of human vasculature. In various embodiments, the modular endoprosthetic system includes a plurality of expandable endoprosthesis components that are coupled together to define the modular endoprosthetic system, wherein the modular endoprosthetic system provides for retrograde perfusion of a branch vessel from a main vessel.

BIOVESSELS FOR USE IN TISSUE ENGINEERING

Described herein are bioengineered constructs and methods of producing the same. The constructs and methods disclosed herein can be applied towards, for example, the generation of vascular grafts to treat cardiovascular disease. 2. The vascular graft of claim 1 , wherein the primary channel bifurcates at the second opening into two secondary channels.3. The vascular graft of claim 1 , wherein the polymer is biodegradable.4. The vascular graft of claim 1 , wherein the polymer is biocompatible.5. The vascular graft of claim 1 , wherein the polymer is a polyester.6. The vascular graft of claim 1 , wherein the polymer is polycaprolactone.7. The vascular graft of claim 1 , wherein the cells of the viable cell-infused extracellular matrix material are stem cells.8. The vascular graft of claim 1 , wherein the extracellular matrix material comprises a basement membrane matrix.9. The vascular graft of claim 1 , wherein the plurality of microchannels within the microstructure of the first void space are arranged to form a regular pattern.10. The vascular graft of claim 9 , wherein the pattern is hexagonal.11. The vascular graft of claim 1 , wherein the plurality of microchannels contain cells.12. The vascular graft of claim 1 , wherein the primary channel has a luminal diameter of from about 1 cm to about 10 cm.13. The vascular graft of claim 1 , wherein the first void space has a thickness of from about 1 mm to about 2 cm.14. The vascular graft of claim 1 , wherein a diameter of one of the microchannels from the plurality of microchannels is from about 1 μm to about 500 μm.15. The vascular graft of claim 1 , wherein the cylindrical hollow body comprises a first end and a second end claim 1 , and the first opening is at the first end claim 1 , and the second opening is at the second end claim 1 , wherein the first opening and the second opening form a straight passage through the cylindrical hollow body.16. The vascular graft of claim 1 , wherein the primary channel further ...

DOCKING GRAFT FOR PLACEMENT OF PARALLEL DISTALLY EXTENDING GRAFTS ASSEMBLY AND METHOD

The techniques of this disclosure generally relate to an assembly including a docking graft. The docking graft includes a main graft defining a main lumen, a first internal lumen within the main lumen, a second internal lumen within the main lumen, and a main docking lumen within the main lumen. The first and second internal lumens are configured to receive first and second bridging stent graft therein. The main docking lumen is configured to receive a tube graft therein. The first internal lumen, the second internal lumen, and the main docking lumen being parallel to one another and extending an entire length of the docking graft when the docking graft is in a relaxed configuration. The docking graft forms the foundation, or anchor device, for attachment of the first bridging stent graft, the second bridging stent graft, and the tube graft within the aorta. 1. An assembly comprising: a main graft defining a main lumen;', 'a first internal sleeve defining a first internal lumen within the main lumen; and', 'a second internal sleeve defining a second internal lumen within the main lumen, the main lumen, the first internal lumen, and the second internal lumen being parallel to one another and extending an entire length of the docking graft from a proximal end of the docking graft to a distal end of the docking graft when the docking graft is in a relaxed configuration., 'a docking graft comprising2. The assembly of claim 1 ,wherein the main graft comprises graft material and at least one stent;the first internal sleeve comprises graft material and at least one stent; andthe second internal sleeve comprises graft material and at least one stent.3. The assembly of wherein the first internal sleeve and the second internal sleeve are coupled to an inner surface of the main graft.4. The assembly of further comprising an attachment means coupling the first internal sleeve and the second internal sleeve to the inner surface of the main graft.5. The assembly of wherein the ...

Three dimensional printing modality combining fused deposition modeling and electrospinning

Disclosed herein is an apparatus for fabricating a branching structure, the apparatus comprising: a flexible, electrically conductive internal electrical field collector comprising a first collector end, a second collector end, a collector outer surface located between both collector ends, a collector longitudinal axis extending through the first collector end and the second collector end, and at least one articulating feature positioned between the first collector end and the second collector end, a compression and rotation mechanism in contact with the first collector end, and a continuously formed mandrel that can include branches, having a first mandrel circumference with a mandrel inner circumference larger than the collector outer circumference and positionable over the internal electrical field collector and a second mandrel located at sufficient distance outside the first mandrel to facilitate attraction of electruspun fibers. Also disclosed are methods of manufacturing the branching structure, and grafts thereof.

ENDOVASCULAR IMPLANTS AND DEVICES AND METHODS FOR ACCURATE PLACEMENT

Various systems, devices, and methods for endovascular implants and accurate placement thereof are disclosed. The disclosed implants include a proximal implant segment, a distal implant segment, connector struts connecting the proximal implant segment to the distal implant segment, and a side opening between the proximal implant segment and the distal implant segment. The disclosed implants can be used to create an arteriovenous fistula or connect one vessel of the body to another by placement of the proximal implant segment and the distal implant segment within the vessels to be connected. The disclosed implants can include one or more anchors for securing the implant in place with respect to the vessels of the body it is connecting. The disclosed implants can also include a continuous strut or ring at a distal edge of the proximal implant segment. Also disclosed are methods for accurate percutaneous placement of the implants disclosed, and a device for percutaneous delivery. 1. A system for creating an arteriovenous fistula in an arm of a patient , the system comprising:an endovascular delivery device configured for access into the arm of the patient, wherein the endovascular delivery device is configured to be advanced into a superficial vein, into a perforator vein, into a deep vein, and into an artery adjacent to the deep vein; and a proximal implant segment comprising a proximal end and a distal end, the proximal implant segment being releasable from the endovascular delivery device to transform from a radially compressed configuration to a radially expanded configuration in which the proximal implant segment extends through the perforator vein and the deep vein with the proximal end of the proximal implant segment positioned within the perforator vein; and', 'a distal implant segment connected to the proximal implant segment, the distal implant segment being releasable from the endovascular delivery device to transform from a radially compressed configuration ...

MULTI-COMPONENT STENT-GRAFT SYSTEM FOR IMPLANTATION IN A BLOOD VESSEL WITH MULTIPLE BRANCHES

A multi-component stent-graft system includes a first stent-graft, and second, third, and fourth branching stent-grafts. The first stent-graft is shaped so as to define, when in a radially-expanded state, proximal and distal superior first lateral openings facing in a first radial direction, and a distal inferior first lateral opening facing a second radial direction generally opposite the first radial direction. The second, third, and fourth branching stent-grafts are configured assume radially-expanded states, wherein the first, the second, the third, and the fourth stent-grafts are configured such that the branching stent-grafts form respective blood-impervious seals with the first stent-graft around the distal inferior first lateral opening, the distal superior first lateral opening, and the proximal superior first lateral opening, respectively, when the branching stent-grafts are disposed therethrough, respectively, and the first, the second, the third, and the fourth stent-grafts are in their radially-expanded states. 125-. (canceled)26. Apparatus comprising a multi-component stent-graft system , which comprises:a first stent-graft, which is shaped so as to define, when in a radially-expanded state, proximal and distal superior first lateral openings facing in a first radial direction, and a distal inferior first lateral opening facing a second radial direction generally opposite the first radial direction, the proximal and distal superior first lateral openings and distal inferior first lateral opening having respective perimeters; andsecond, third, and fourth branching stent-grafts, which are configured assume radially-expanded states, wherein the first, the second, the third, and the fourth stent-grafts are configured such that the branching stent-grafts form respective blood-impervious seals with the first stent-graft around the distal inferior first lateral opening, the distal superior first lateral opening, and the proximal superior first lateral opening ...

STENT GRAFT WITH FENESTRATION LOCK AND METHODS OF USE

A stent graft includes a luminal graft component defining at least one fenestration. At least one ligature traverses the fenestration and at least partially defines an opening within the fenestration that secures a branch prosthesis. The stent graft is implanted in a patient to thereby treat an arterial aneurysm, such as an aortic aneurysm in a region of the aorta that includes at least one arterial branch, including juxtarenal and short-neck aortic aneurysms. 1. A method for treating an arterial aneurysm , comprising the steps of: i) a luminal graft component having a proximal open end, a distal open end, and defining a main lumen extending from the proximal open end to the distal open end, the luminal graft component defining at least one fenestration, and', 'ii) at least one ligature traversing the at least one fenestration, the ligature, a fenestration lock at the fenestration, alone or in combination with the luminal graft component, constituting a fenestration, whereby a branch prosthesis can be secured by the fenestration lock;, 'a) delivering a stent graft through an artery to an aneurysm of a patient, the aneurysm spanning a region of the artery that includes at least one arterial branch, the stent graft includingb) substantially aligning the fenestration with the arterial branch at the aneurysm site of the patient; andc) delivering a branch prosthesis through the proximal open end or the distal open end of the luminal graft component of the stent graft, and through the fenestration lock to the associated arterial branch, thereby treating the arterial aneurysm.2. The method of claim 1 , wherein the at the at least one ligature is at least one member selected from the group consisting of sutures claim 1 , rubber bands claim 1 , latex claim 1 , cloth claim 1 , and metal.3. The method of claim 1 , wherein the at least one ligature includes an elastic material.4. The method of claim 1 , wherein the at least one ligature includes a shape memory alloy.5. The ...

DEVICES AND METHODS FOR ANATOMIC MAPPING FOR PROSTHETIC IMPLANTS

A method of generating a patient-specific prosthetic includes receiving anatomic imaging data representative of a portion of a patient's anatomy. A first digital representation of the anatomic imaging data is defined. The first digital representation of the anatomic imaging data is modified. A second digital representation of the portion of the patient's anatomy is defined based on the modifying of the first digital representation of the anatomic imaging data. A patient-specific prosthetic template of the portion of the patient's anatomy is generated based at least in part on the second digital representation of the anatomic imaging data. 166.-. (canceled)67. A method , comprising:receiving a digital representation of a portion of a patient's blood vessel, the digital representation including data representative of a first location of an anatomic feature of the patient's blood vessel;modifying the digital representation to determine a second location of the anatomic feature of the patient's blood vessel, the second location different than the first location; andgenerating a model of the portion of the patient's blood vessel, the model including data representative of the second location of the anatomic feature.68. The method of claim 67 , wherein the digital representation is based on imaging data associated with the portion of the patient's blood vessel.69. The method of claim 67 , wherein the model is a patient-specific template.70. The method of claim 67 , wherein the second location is calculated from a reference point.71. The method of claim 67 , wherein determining the second location of the anatomic feature is calculated automatically.72. The method of claim 71 , wherein the automatic calculation of the second location is based on a user input.73. The method of claim 72 , wherein the user input includes at least one of an anatomic feature of the patient claim 72 , a property of a prosthesis claim 72 , a delivery device for delivering a prosthesis to the ...

METHOD AND APPARATUS FOR ULTRASOUND-GUIDED DELIVERY OF VASCULAR DEVICES

Delivery devices and vascular devices are described for addressing a target site within a body lumen. The delivery device includes one or more ultrasound transducers positioned to transmit and receive ultrasound signals so as to provide an image of an interior of the patient's blood vessel within which the vascular device is disposed in real time, as the procedure is taking place. Using the images provided by the ultrasound transducers, the longitudinal and rotational position of the delivery device (and the vascular device constrained therein) may be adjusted to align the vascular device with the patient's vasculature. In some examples, the vascular device being delivered includes fenestrations, whereas in others the vascular device integral branch grafts. 1. A delivery device for delivering a vascular device to a target site within a body lumen comprising:an outer sheath defining a first lumen, wherein the outer sheath defines a distal end thereof, and wherein the first lumen is configured to receive a vascular device therein;a leading member configured to be disposed proximate the distal end of the outer sheath and to be engaged with the outer sheath when the delivery device is in a delivery configuration; andat least a first ultrasound transducer on the leading member, wherein the first ultrasound transducer is disposed proximate an outer surface of the leading member for transmitting and receiving ultrasound signals so as to provide at least a first image of an interior of a patient's blood vessel, such that a longitudinal position and a rotational position of the vascular device with respect to the patient's blood vessel and surrounding anatomical structures may be determined and adjusted through manipulation of the delivery device based on the image provided.2. The delivery device of claim 1 , further comprising an inner sheath at least partially disposed within the first lumen of the outer sheath and configured to be axially movable with respect to the outer ...

Endovascular grafts and methods for extended aortic repair

An endovascular graft including a stent graft and a surgical graft is provided. The stent graft can include an elongated body having a collapsed and expanded configuration and include a frame structure covered by a compression sleeve that retains the elongated body in the collapsed configuration until deployment of the stent graft. The endovascular graft can include a first cuff member sized and dimensioned to extend into a lumen of an aortic arch branch vessel when the endovascular graft is implanted in a subject. The frame structure can include a backstop sized and dimensioned to extend into the first cuff member when the endovascular graft is implanted in the subject. The surgical graft can be partially attached to the stent graft at a proximal end portion thereof.

SYSTEMS AND METHODS FOR TREATMENT OF AORTIC DISSECTION

The present disclosure involves an ascending aorta graft apparatus and methods for use thereof. The graft is specially designed to treat an aortic dissection or aneurysm occurring at least partially in the region of the ascending aorta and the aortic arch. The ascending aorta graft features at least one bypass or jump graft that establishes fluid communication between two portions of the ascending aorta graft and enables the surgeon to expeditiously reestablish perfusion to at least one artery of the aortic branch immediately upon surgical placement of the ascending aorta graft. An integrated assembly is created with additional stent grafts and a thoracic stent graft that traverses the descending aorta. 1. A synthetic graft for repairing an aortic dissection or aneurysm comprising:an ascending aortic graft configured to replace a section of a native ascending aorta at a site between a sinotubular junction and a brachiocephalic trunk of a patient, having a body with a first portion and a second portion, wherein the body defines a first fluid communication between the first body portion and the second body portion; andat least one jump graft having opposing ends connected to the first body portion and the second body portion and that establishes an additional fluid communication between the first portion and the second portion.2. The synthetic graft of claim 1 , wherein the ascending aortic graft comprises three jump grafts.3. The synthetic graft of claim 1 , wherein the at least one jump graft comprises a working tube establishing an open connection between a proximal opening of the working tube and an interior space of the jump graft.4. The synthetic graft of claim 1 , wherein the first portion of the body comprises an access port establishing an open communication between a proximal opening of the access port and an interior space of the body of the ascending aortic graft.5. The synthetic graft of claim 1 , wherein the ascending aortic graft further comprises a ...

FENESTRATED STENT GRAFTS

A stent graft including a tubular wall with at least one fenestration including a peripheral reinforcement around at least part of the fenestration. There can also be a tubular extension. The side arm includes a stent and a cover and extends from and is in fluid communication with the fenestration and the stent graft. The stent may be a self expanding stent. The ring and/or tubular extension provides better support and sealing for an extension arm. The fenestration can be circular or if towards the ends of the stent graft may be in the form of a U-shape with an open end. 119-. (canceled)20. A stent graft comprising a tube of graft material comprising:a first end having an edge,a second end having an edge,a first tubular body portion directly adjacent the first end and having a first diameter,a second tubular body portion directly adjacent the second end and having a second diameter,a first tapered portion directly adjacent the first tubular body portion,a second tapered portion directly adjacent the second tubular body portion,an intermediate tubular body portion disposed between the first and second tapered portions having a sidewall and a diameter less than both of the first and second tubular body portions,a series of zig zag stent rings extending from the first end to the second end, each of the series of zig zag stent rings comprising a series of adjacent struts and bends between the struts,first and second fenestrations in the sidewall of the intermediate tubular body portion that are circumferentially from each other,a third fenestration circumferentially between the first and second fenestrations and longitudinally spaced from the first and second fenestrations,first, second and third tubular extensions each extending from an aperture in the intermediate tubular body portion, each of the first, second and third tubular extensions having a first end attached to the intermediate tubular body portion, a second free end defining an opening, a ring about the ...

Devices and methods for treating aneurysms and other vascular conditions

A fenestrated aortic cuff is configured to be delivered endovascularly to a target region, deployed, fastened, and sealed to a vessel wall, e.g., in a neck region of an aortic aneurysm. Example fenestrated cuffs provide a suitable landing zone for a commercially available endograft, which may be, in some cases, positioned below or above the renal arteries in order to complete exclusion of an abdominal aortic aneurysm (AAA) or a thoracic aortic aneurysm (TAA), respectively, from systematic circulation. In some cases, fenestrated cuff function is facilitated and improved by employing active fixation and sealing mechanisms, including, e.g., helical fasteners, which may allow deployment of the fenestrated cuff in short neck regions with limited sealing area.

PROSTHESIS FOR REPAIRING A BLOOD VESSEL AND METHOD

A prosthesis for repairing a blood vessel, wherein the prosthesis is inserted intraluminally and fixed in the vessel so as to isolate a diseased section thereof and maintain the flow of blood from the vessel to collateral vessels involved the diseased section, and the prosthesis comprises a stent support and a flexible fabric liner of woven material comprising a plurality of concentric layers, wherein each of said layers has a very open fabric web which allows the passage of blood flow through the layers during the installation or the prosthesis but which allows the sealing of layers once the prosthesis is installed. A method is also provided for safe installation of the prosthesis. 1. A prosthesis for repairing blood vessels , wherein the prosthesis is intraluminally inserted and fixed into one blood vessel of a patient , covering a diseased section of the vessel , with the blood vessel having collateral vessels the perfusion of which must be guaranteed during and after the implantation of the prosthesis , the prosthesis comprising:a) a main prosthesis comprising:i) a expandable support for firmly affixing into said blood vessel and along said diseased section, andii) a liner made of a fabric material comprised of a plurality of concentric layers, wherein each layer provides a web that is open enough to allow the blood flow passing therethrough, and the layers are overlapped all together to form a wall of the main prosthesis defining labyrinthine interstices capable of being open during a controlled period of time for the installation and implantation of the main prosthesis, which interstices are sealed by the fibrin of the patient's blood after said period of time has elapsed, wherein said interstices formed by the web of each one of the overlapping layers are capable of being opened by a non cutting element passing through the interstices to form at least one passage through the wall formed by the plurality of concentric layers, andb) at least one interconnecting ...

Prosthesis with branched portion

Examples of prostheses are provided having an internal branch. A tubular graft body of the prosthesis defines a main lumen extending between an inflow end and an outflow end of the graft body. A stent structure is coupled along the graft body. A trough is at least partially defined by a trough wall extending into the main lumen from a sidewall of the graft body. A side branch defines a branch lumen and extends from the trough within the main lumen towards one of the inflow or outflow ends of the graft body. A branch lumen facing surface of the trough wall is a continuous surface with an outer surface of the sidewall of the graft body. A boundary of the trough may be configured to provide a smooth transition surface between the trough and the sidewall.

Integrated Production of Abdominal Aortic Stents Using 3D Printing

An integrated, automated method to make various abdominal aortic stents with 3D printing technology and computerized recognition algorithms. Cost, risk, and time from assessment to recovery are reduced. 1a. the means for performing the segmentation/extraction of a predetermined abdominal aorta and associated branches from a computer-assisted tomography or magnetic resonance imaging scan of said predetermined abdominal aorta and associated branches,b. the means for creating a parameter file specifying the structure and measurements of said abdominal aorta,c. the means for creating a stereolithography file, based on said parameter file of said abdominal aorta, for a predetermined stent design for said abdominal aorta,d. the means for transmitting said stereolithography file to a Computer Aided Design program for manual review and possible modifications, ande. the means for printing said stereolithography file, possibly modified by said Computer Aided Design program, on said three-dimensional printer,. A method of using a computer processor and a three-dimensional printer by applying said computer processor to the execution of formulas and logical flow comprising the steps of: The data from a Computed Tomography (CT) scan is a collection of two-dimensional slices that are stored in a Digital Imaging and Communications in Medicine (DICOM)-format file that can be viewed with open-source software. shows a three-dimensional (3D) reconstruction of an abdominal CT scan. The mathematics associated with CT is quite sophisticated and advances rapidly. Occasionally, Magnetic Resonance Imaging (MRI) is used instead of CT, but it is better suited for soft organs, but the data files produced follow the DICOM standard in either event.Three-dimensional (3D) printing is still in its infancy, and the devices range from consumer units using inexpensive filaments and costing hundreds of dollars to industrial systems using special resins and costing almost a million dollars. Our ...

METHOD AND APPARATUS FOR ULTRASOUND-GUIDED DELIVERY OF VASCULAR DEVICES

Delivery devices and vascular devices are described for addressing a target site within a body lumen. The delivery device includes one or more ultrasound transducers positioned to transmit and receive ultrasound signals so as to provide an image of an interior of the patient's blood vessel within which the vascular device is disposed in real time, as the procedure is taking place. Using the images provided by the ultrasound transducers, the longitudinal and rotational position of the delivery device (and the vascular device constrained therein) may be adjusted to align the vascular device with the patient's vasculature. In some examples, the vascular device being delivered includes fenestrations, whereas in others the vascular device integral branch grafts. 1. A delivery device for delivering a vascular device to a target site within a body lumen comprising:an outer sheath defining a first lumen, wherein the outer sheath defines a distal end thereof, and wherein the first lumen is configured to receive a vascular device therein;a leading member configured to be disposed proximate the distal end of the outer sheath and to be engaged with the outer sheath when the delivery device is in a delivery configuration; andat least a first ultrasound transducer and a second ultrasound transducer, the first ultrasound transducer being disposed proximate the distal end of the outer sheath and the second ultrasound transducer being disposed proximate a distal tip of the leading member, wherein each ultrasound transducer is disposed proximate an outer surface of the leading member for transmitting and receiving ultrasound signals so as to provide at least first and second images of an interior of the patient's blood vessel, such that a longitudinal position and a rotational position of the vascular device with respect to the patient's blood vessel and surrounding anatomical structures may be determined and adjusted through manipulation of the delivery device based on the images ...

Stent graft

The stent graft ( 10 ) comprises a cylinder comprising a graft material in the form of a film and a stent that supports the cylinder. Further, the stent graft ( 10 ) is inserted within a region from the ascending aorta to the sinus of valsalva, and the stent graft comprises cylindrical body section ( 11 ) arranged in the ascending aorta and the sinus of valsalva section ( 12 ) arranged in the sinus of valsalva and having an inner diameter larger than that of the body section ( 11 ).

Stent graft with valve arrangement

A stent graft has a cylindrical wall, an internal lumen within the cylindrical wall and a fenestration in the wall. The fenestration is closed off by a valve arrangement to prevent the flow of liquids from within the internal lumen to outside of the wall. The valve arrangement is a tube of graft material which can be closed off by pressure on its outside surface. The end of the tube remote from the fenestration can be held shut by having its periphery fastened to a flattened resilient ring. Fluid pressure on the tube of graft material causes the tube to close off to prevent fluid flow therethrough and by resilient deflection of the resilient ring the end of the tube of graft material can be opened to enable the passing of a medical device therethrough.

Methods and apparatus for percutaneous bypass graft

Methods and apparatus for a percutaneous bypass graft system according to various aspects of the present technology include a graft section comprising a dual-sided fixation system at the anastomosis site and a tamper sheath configured to provide enhanced control during installation. The dual-sided fixation system may comprise a plurality of barbs configured to secure the graft section to an internal and external portion of a target vessel. The tamper sheath comprises a cuff at a distal end that is configured to be positioned against an outer surface of the target vessel during the percutaneous procedure.

Secured strand end devices

A woven, self-expanding stent device has one or more strands and is configured for insertion into an anatomical structure. The device includes a coupling structure secured to two different strand end portions that are substantially aligned with each other. The two different strand end portions include nickel and titanium. The coupling structure is not a strand of the device.

Temporary diameter reduction constraint arrangement for a stent graft in combination with a stent graft

A temporary diameter reduction constraint arrangement for a stent graft in combination with a stent graft is disclosed. The stent graft has a proximal end and a distal end and comprises a biocompatible graft material tube and a plurality of longitudinally spaced apart self-expanding stents fastened thereto, including at least an end stent and a plurality of intermediate stents. The constraint arrangement comprises: an elongate receiver extending longitudinally within the graft material tube; a first wire extending longitudinally along the graft material tube in a first serpentine pattern; and a second wire extending longitudinally along the graft material tube in a second serpentine pattern, wherein at least one of the first and second wires repeatedly loops over the receiver along a longitudinal length of the stent graft thereby securing the stent graft to the receiver. In one embodiment there is also a plurality of loops of thread to reduce the stent graft.

Vessel access catheter

The described invention provides an endovascular device comprising a tube comprising a first end comprising a bifurcation and a second end comprising an opening. The bifurcation at the first end comprises a first branch and a second branch. The opening at the second end comprises a primary opening and a secondary opening. The first branch and the primary opening form a working lumen. The second branch and the secondary opening form a support lumen. The described invention further provides an endovascular device comprising a tube comprising a side-hole, a first segment comprising a primary opening and a second segment. The side-hole and the first segment form a working lumen. The second segment forms a support lumen. 2. The medical device according to claim 1 , wherein length of said first segment ranges from at least 10 cm to at least 100 cm.3. The medical device according to claim 1 , wherein said second segment extends from at least 0.1 cm to at least 60 cm in length from said side-hole.4. The medical device according to claim 1 , wherein the internal diameter of said working lumen ranges from about 0.0254 cm (0.0100 inches) to about 26 Fr (0.3410 inches).5. The medical device according to claim 4 , wherein the internal diameter of said working lumen ranges from about 4 Fr (0.0530 inches) to about 12 Fr (0.1580 inches).6. The medical device according to claim 1 , wherein said second device comprises a catheter claim 1 , a therapeutic balloon claim 1 , a therapeutic stent claim 1 , or another endovascular device.7. The medical device according to claim 1 , wherein said tube further comprises an angled extension at said side hole.8. The medical device according to claim 7 , wherein the angle of said angled extension ranges from about 10 degrees to about 180 degrees.9. The medical device according to claim 7 , wherein said angled extension comprises a shape memory polymer (SMP) claim 7 , a shape memory alloy (SMA) or a combination thereof.10. The medical device ...

APPARATUS AND METHOD OF PLACEMENT OF A GRAFT OR GRAFT SYSTEM

A fenestrated graft deployment system, with a delivery catheter having a catheter body, a first fenestration alignment device, and an endoluminal prosthesis having a main graft body having a lumen therethrough and a first opening laterally therein. The first fenestration alignment device is configured to extend through at least a portion of the delivery catheter and is configured to be axially moveable relative to the first guidewire. The first fenestration alignment device can cause the main graft body adjacent to the first opening to move with the end of the first fenestration alignment device to allow an operator to align the first opening in the side of the endoluminal prosthesis with an ostium of a target branch vessel into which said first opening is to extend and act as a guide and seal for a subsequently delivered branch graft endoluminal prosthesis. 120-. (canceled)21. A fenestrated graft deployment system , comprising:a catheter body; anda first fenestration alignment device extending through at least a portion of the catheter body, the first fenestration alignment device configured to be axially moveable between a first position and a second position, the first fenestration alignment device being prepositioned within the delivery catheter when the delivery catheter is in a predeployment state;wherein the first fenestration alignment device comprises a tubular shaped member and a protrusion projecting from an outside surface of a distal portion of the tubular shaped member, the protrusion comprising a non-circular cross-sectional shape and being sized and configured to engage a lateral opening of an endoluminal prosthesis when the first fenestration alignment device is advanced toward the second position.22. The fenestrated graft deployment system of claim 21 , further comprising a first guidewire prepositioned within the delivery catheter when the delivery catheter is in the predeployment state.23. The fenestrated graft deployment system of claim 22 , ...