Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год

Применить Всего найдено 5048. Отображено 100.
24-05-2012 дата публикации

Devices and methods for in situ fenestration of a stent-graft at the site of a branch vessel

Номер: US20120130478A1
Автор: Edward E. Shaw
Принадлежит: WL Gore and Associates Inc

The present disclosure includes a stent-graft comprising a first portion that is configured to engage a vessel wall, a second portion that is configured not to engage the vessel wall, and a perfusion window that is configured to permit blood flow. The stent-graft may further comprise a transition portion between the first portion and the second portion, and the perfusion window may be formed in the first portion, the second portion, and/or the transition portion. In a variety of embodiments, one of the first and the second portion may have a smaller diameter than the other. Similarly, in a variety of embodiments, the transition portion may be frustoconically shaped.

Подробнее
31-05-2012 дата публикации

Two valve caval stent for functional replacement of incompetent tricuspid valve

Номер: US20120136430A1
Автор: Jan Peregrin, Jan Sochman
Принадлежит: Cook Medical Technologies LLC

A two valve caval stent for functional replacement of an incompetent tricuspid valve. The device is designed for minimally invasive percutaneous transcatheter placement and includes two stents connected by a bridge sized to span the right atrium, and two valves anchored by the stents in the superior and inferior vena cavas. Each of the valves optionally has a conical shape divided by supporting struts into three cusps that simulate the action of a native tricuspid valve.

Подробнее
31-05-2012 дата публикации

Stent Graft System

Номер: US20120136431A1
Автор: Wei-Hui Chen
Принадлежит: Individual

The stent graft system in accordance with the present invention has a trunk, a left subclavian tube, a left common carotid tube and a brachiocephalic tube. The trunk is tubular and expandable and has a descending end, an ascending end, a left subclavian mount, a left common carotid mount and a brachiocephalic mount, for receiving the aforementioned branch tubes that are elastic and self-expandable for respectively connecting the left subclavian artery, the left common carotid artery and the brachiocephalic artery to the trunk. With the above-described structure, the present invention allows fast determination of a suitable trunk and branch tubes for a patient and allows a medical institute to prepare compatible branch tubes and trunks for a composite stent graft system instead of numerous stent grafts of various combinations of differently sized tubular bodies and branches, wherein the former requires significantly less warehousing cost than the latter.

Подробнее
05-07-2012 дата публикации

Venous nitinol embolization inserts

Номер: US20120172908A1
Автор: Karl F. Grace
Принадлежит: Cook Inc

A venous nitinol embolization insert for restricting blood flow includes a tubular member and an embolization material attached to the tubular member. The embolization insert provides a predetermined blood flow rate based on experimental data. A method of controlling restriction of blood flow to a targeted vascular site within a patient's body includes selecting an insert that provides a predetermined blood flow rate corresponding to a desired blood flow rate. The embolization insert is selected from a plurality of embolization inserts that provide varied blood flow rates.

Подробнее
26-07-2012 дата публикации

Biodegradable endoprostheses and methods for their fabrication

Номер: US20120187606A1
Принадлежит: Elixir Medical Corp

Biodegradable endoprostheses are formed from amorphous polymers having desirable biodegradation characteristics. The strength of such amorphous polymers is enhanced by annealing to increase crystallinity without substantially increasing the biodegradation time.

Подробнее
16-08-2012 дата публикации

System and method for delivering a stent to a bifurcated vessel

Номер: US20120209368A1
Принадлежит: ABBOTT LABORATORIES

A stent delivery catheter system for accurately positioning a stent in a bifurcated vessel is disclosed. The system includes a catheter having a terminal portion and distal tip that is placed in a main branch of the vessel proximate the bifurcation. A fixed guidewire is attached to distal tip. A port is defined in the terminal portion of the catheter. The port is aligned with an ostium of a side branch of the bifurcated vessel to allow the passage of a stent delivery device, such as a balloon catheter having a stent crimped thereon, into the side branch. Radiopaque bands are positioned on opposite ends of the port. A positioning balloon is included on a surface of the catheter opposite the port and is selectively inflatable to position the radiopaque bands adjacent the side branch ostium. The radiopaque bands are referenced to place the stent proximate the side branch ostium.

Подробнее
04-10-2012 дата публикации

Stent designs having enhanced radiopacity

Номер: US20120253454A1
Автор: Kieran Costello
Принадлежит: Cook Medical Technologies LLC

The present embodiments provide stents for use in medical procedures. In one embodiment, a stent comprises a first flanged region and a body region. A first diameter of the first flanged region is greater than a second diameter of the body region when the stent is in an expanded deployed state. A proximal junction is formed between the first flanged region and the body region. The proximal junction comprises at least one strut extending from the distal end of the first flanged region in a distal direction towards the proximal end of the body region. A strut at the proximal end of the body region is disposed around at least a portion of the strut of the proximal junction. The overlap between the strut at the proximal end of the body region with the strut of the proximal junction causes an increased radiopaque effect at the proximal junction.

Подробнее
15-11-2012 дата публикации

Vascular remodeling device

Номер: US20120290067A1
Принадлежит: TYCO HEALTHCARE GROUP LP

Described herein are flexible implantable devices or stents that can conform to the shape of vessels of the neurovasculature. In some embodiments, the devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. In some embodiments, a vascular remodeling device includes a first section and a protruding section. During deployment, the device expands from a compressed configuration to an expanded configuration. The first section anchors the device in an afferent vessel and/or in an efferent vessel of a bifurcation and the protruding section is positioned in the junction of the bifurcation having an aneurysm and across the neck of the aneurysm or at least partially within the aneurysm.

Подробнее
22-11-2012 дата публикации

Thoracic aorta stent graft

Номер: US20120296414A1
Автор: David Ernest Hartley

A stent graft for placement in the thoracic arch of a patient has a tubular body defining a main lumen therethrough, a plurality of zig zag stents along the tubular body, each of the stents comprising a plurality of struts and bends, the bends being between adjacent struts. At least a first stent and an adjacent second stent having at least a pair of adjacent bends on the first stent aligned with an adjacent pair of bends on the second stent, whereby a first pair of adjacent struts of the first stent and a second pair of adjacent struts of the second adjacent stent together define a diamond shape region. A recess is within the diamond shaped region with the recess extending into the lumen of the tubular body. A fenestration extending into the tubular body within the recess in the diamond shaped region and a graft tube leading from the fenestration into the main lumen. There can be one, two or three diamond shaped regions, recesses, fenestrations and graft tubes Proximally of the or each diamond shaped region the tubular body has a first diameter, distally of the diamond shaped region the tubular body has a second diameter and in the region of the tubular body around the diamond shaped region the tubular body has a third diameter, the first diameter being greater than the second diameter and both the first and second diameter being greater than the third diameter whereby a central region is defined which will allow circumferential blood flow during an operation out of the graft tube into the recess and then into the central region.

Подробнее
27-12-2012 дата публикации

Devices and methods for treatment of vascular aneurysms

Номер: US20120330343A1
Принадлежит: Kim Steven W, Shiu Brian K

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Подробнее
28-02-2013 дата публикации

Deformable Lumen Support Devices and Methods of Use

Номер: US20130053943A1
Принадлежит: CeloNova Stent Inc

Lumen support devices and methods of their use are provided. A lumen support includes one or more plastically deformable cells having two stable configurations with no stable configurations between the two stable configurations. The lumen support device may be plastically deformed to other stable configurations.

Подробнее
07-03-2013 дата публикации

Balloon catheters and methods for use

Номер: US20130060316A1
Принадлежит: Ostial Corp

Apparatus and methods are provided for flaring a stent deployed within a branch vessel including an ostium communicating with a main vessel, a first end of the stent extending at least partially from the branch. A catheter is provided that includes a first balloon carried on its distal end, and a second balloon that includes a distal section overlying at least a portion of the first balloon and a proximal section. The catheter distal end is introduced into the main vessel and positioned through the ostium and stent into the branch until the first balloon is disposed within the stent. The first balloon is expanded to anchor the stent, and the second balloon is expanded to flare the first end of the stent. Optionally, the first balloon is expanded further, e.g., to expand the stent within the branch body lumen and/or dilate the lesion.

Подробнее
18-04-2013 дата публикации

Method and apparatus for treating a patient by intentionally occluding a blood vessel, including method and apparatus for inducing weight loss in a patient by intentionally occluding the celiac artery

Номер: US20130096580A1
Принадлежит: Reynolds M. Delgado, William E. Cohn

A method for inducing weight loss in a patient, the method comprising: intentionally occluding a blood vessel so as to create hypoperfusion in a gastrointestinal organ serviced by the blood vessel, whereby to interfere with normal gastrointestinal function and thereby induce weight loss in a patient.

Подробнее
09-05-2013 дата публикации

Protuberant Aneurysm Bridging Device and Method of Use

Номер: US20130116774A1
Принадлежит: Reverse Medical LLC

A bridging device for supporting occlusive masses within an aneurysm located at a vascular bifurcation.

Подробнее
23-05-2013 дата публикации

Branch stent graft deployment and method

Номер: US20130131777A1

A deployment device for deploying a self-expanding fenestrated stent graft. The device includes a fenestrated stent graft retained on an introducer. The introducer includes a main catheter and an auxiliary catheter preloaded within the introducer and extending from distal the distal end of the stent graft, into the lumen of the stent graft and through the fenestration.

Подробнее
22-08-2013 дата публикации

Medical device delivery system and deployment method

Номер: US20130218257A1
Принадлежит: Cook Medical Technologies LLC

An aortic stent-graft may include a tubular graft extending from a proximal end to a distal end, the graft comprising a proximal sealing portion and an intermediate portion, wherein a proximal end of the intermediate portion abuts the distal end of the proximal sealing portion. At least one sealing stent may be attached to the proximal sealing portion. A first fenestration window is disposed in the intermediate portion. The first fenestration window has a length determined by the equation L=1.23*D−24 millimeters, where L is the length of the first fenestration window. D is between about 24 millimeters and 45 millimeters.

Подробнее
29-08-2013 дата публикации

Stent wires, and method for manufacturing such stent wires and stents

Номер: US20130226282A1
Принадлежит: MEDISOURCEPLUS CO Ltd

A method for manufacturing stent wires includes preparing three or more annular stent wires which has alternately arranged peaks and valleys, interconnecting the first and second stent wires, such that predetermined peaks of the second stent wire are caught in predetermined valleys of the first stent wire, passing a valley of a third stent wire below a free valley of the first stent wire and a free peak of the second stent wire, and interconnecting the third and second stent wires such that a peak of the third stent wire is caught in a valley of the second stent wire. The stent wires are connected in a stacked manner, thereby simplifying the manufacturing process, lengthening the lifespan of the stent wires, and improving the strength of the connection between two adjacent stent wires.

Подробнее
03-10-2013 дата публикации

Devices and methods for treatment of vascular aneurysms

Номер: US20130261724A1
Принадлежит: Brian K. Shiu, Steven W. Kim

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Подробнее
17-10-2013 дата публикации

Debranching Great Vessel Stent Graft and Methods for Use

Номер: US20130274853A1
Автор: Patrick W. KELLY
Принадлежит: SANFORD HEALTH

A debranching Great vessel stent graft and methods for its use, where the stent graft comprises, a main body stent graft with a first bifurcation defining a first leg and a second leg, the main body stent graft has distal and proximal ends, the main body stent graft has a diameter at the proximal end in the range from about 18 mm to about 28 mm, the first leg and the second leg each have a diameter in the range from about 12 mm to about 18 mm, the distance from the proximal end of the main body to the distal end of the first leg is in the range from about 30 mm to about 50 mm, and the distance from the proximal end of the main body to the distal end of the second leg is in a range from about 50 mm to about 70 mm.

Подробнее
05-12-2013 дата публикации

Absorbable Blood Vessel Stent

Номер: US20130325102A1
Принадлежит: Lifetech Scientific Shenzhen Co Ltd

An absorbable blood vessel stent ( 100 ) has a near end and a far end. A tubular patterned structure is formed between the near end and the far end. The patterned structure comprises a plurality of support bars and connection bars ( 2, 3 ). The support bar or the connection bar ( 2, 3 ) comprises a straight line section, a U-shaped section, or an S-shaped section, and at least one through groove or through hole ( 5, 6 ) is provided on at least one support bar. Because of the special structure of the blood vessel stent ( 100 ), the performance of an iron blood vessel stent can be improved, and blood vessel stents made of other absorbable materials can be decomposed more rapidly.

Подробнее
19-12-2013 дата публикации

Method of treating vascular bifurcations

Номер: US20130338751A1
Принадлежит: Tryton Medical Inc

A prosthesis is disclosed for placement across an ostium opening from a main body lumen to a branch body lumen. The prosthesis comprises a radially expansible support at one end, a circumferentially extending link at the other end and at least one frond extending axially therebetween. The circumferential link can comprise a catheter securement portion and a frond engagement portion.

Подробнее
26-12-2013 дата публикации

Fenestrated stent grafts

Номер: US20130345785A1
Принадлежит: Cook Medical Technologies LLC

A stent graft ( 1 ) including a tubular wall ( 3 ) with at least one fenestration ( 40 ) including a peripheral ( 37 ) reinforcement around at least part of the fenestration. There can also be a tubular extension ( 15 ). The side arm includes a stent ( 19 ) and a cover ( 17 ) and extends from and is in fluid communication with the fenestration and the stent graft. The stent may be a self expanding stent. The ring and/or tubular extension provides better support and sealing for an extension arm. The fenestration ( 40 ) can be circular or if towards the ends of the stent graft may be in the form of a U-shape ( 50 ) with an open end.

Подробнее
06-02-2014 дата публикации

Methods of securing a fastener

Номер: US20140039495A1
Принадлежит: P Tech LLC

Embodiments may include an attachable fastener, which may include a bondable material that may be secured to the end of an end effector. Vibration may be tuned to occur at a distal end of the fastener. Accordingly, the fastener may be used to generate heat at a distal point of contact. If the contact surface contains bondable material, that material may be softened. If the fastener includes bondable material at the point of contact, that material may also be softened by heat produced by vibration at the contact area. A hard implant or another polymeric material may function as the anvil.

Подробнее
13-02-2014 дата публикации

Dual net vascular filtration devices and related systems and methods

Номер: US20140046358A1
Принадлежит: WL Gore and Associates Inc

According to one aspect of the disclosure, a dual net vascular filtration device comprises a central frame, a proximal filter net attached to a proximal end of the central frame, and a distal filter net attached to a distal end of the central frame. Upon deployment, the distal filter net can be configured to evert into the proximal filter net.

Подробнее
07-01-2021 дата публикации

Method and Devices for Intracorporeal Bonding of Implants with Thermal Energy

Номер: US20210000515A1
Принадлежит: P Tech LLC

A system for dynamically controlling a weld profile includes a generator, and end effector, a sensor, and a computer. The generator is configured to supply energy based on the weld profile. The end effector operatively connected to the generator and configured to apply vibratory energy and pressure to an object. The sensor configured to provide an output with respect to the object. The computer configured to monitor the output and change the weld profile of the generator based on the output.

Подробнее
07-01-2016 дата публикации

SELF-EXPANDING BIFURCATED STENT

Номер: US20160000588A1
Автор: Johnson Andrew K.
Принадлежит:

A self-expanding stent is disclosed, the self-expanding stent having a collapsed configuration and an expanded configuration. The self-expanding stent has three stent subunits, each including one or more longitudinally-oriented diamonds and one or more axially-oriented diamonds. The subunits are coupled together at a pivot joint. The longitudinally-oriented diamonds are configured to substantially hold their shape in both the expanded configuration of the stent and the collapsed configuration of the stent. The axially-oriented diamonds are configured to expand from the collapsed configuration to the expanded configuration. Expansion of the axially-oriented diamonds creates angulation between the stent subunits at the pivot joint. Thus, the stent can be inserted into a target location through a tubular catheter, once the stent is no longer constrained by the catheter, it will expand to an angled configuration. 1. A self-expanding stent with a collapsed configuration and an expanded configuration , comprising:a first stent component including one or more longitudinally-oriented diamonds and one or more axially-oriented diamonds;a second stent component including a first arm and a second arm, the first and second arm being coupled together at a pivot joint, the first and second arm including one or more longitudinally-oriented diamonds and one or more axially-oriented diamonds;wherein the longitudinally-oriented diamonds are configured to substantially hold their shape in both the expanded configuration of the stent and the collapsed configuration of the stent and the axially-oriented diamonds are configured to expand from the collapsed configuration to the expanded configuration; andwherein the first stent component is coupled to the second stent component adjacent the pivot joint.2. The self-expanding stent of claim 1 , wherein the pivot joint is created by coupling at least one apex of a longitudinally-oriented diamond of the first arm with at least one apex of a ...

Подробнее
07-01-2021 дата публикации

VASCULAR REMODELING DEVICE

Номер: US20210000624A1
Принадлежит:

Vascular remodeling devices can include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchor the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection. 1. An intraluminal device comprising:a proximal section configured to anchor in an afferent vessel;an intermediate section comprising a plurality of struts configured to allow perfusion to efferent vessels;a distal section configured to act as a scaffolding to inhibit herniation of objects out of a neck of a bifurcation aneurysm;wherein each of the plurality of struts is coupled to the distal section at a coupling at a region between a proximal end of the distal section and a distal end of the distal section;wherein the distal section is biased to transition from a compressed state to a radially expanded state when released from a catheter, wherein, while transitioning from the compressed state to the radially expanded state, the distal end moves radially outwardly and proximally relative to the proximal section, and the proximal end of the distal section moves radially inwardly and distally relative to the proximal section.2. The intraluminal device of claim 1 , wherein claim 1 , while in the expanded state claim 1 , the proximal end and the distal end are substantially ...

Подробнее
04-01-2018 дата публикации

REPLACEMENT MITRAL VALVES

Номер: US20180000580A1
Принадлежит:

A prosthetic mitral valve includes an anchor assembly, an annular strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The annular strut frame is disposed radially within the anchor assembly. An atrial end of the annular strut frame is attached to the anchor assembly such that a ventricular end of the annular strut frame is spaced away from the anchor assembly. 1. A prosthetic mitral valve comprising:an anchor assembly comprising a proximal anchor, a distal anchor, and a central portion therebetween;an annular strut frame disposed radially within the anchor assembly, wherein the annular strut frame comprises a cylindrical ventricular portion and flared atrial portion, the flared atrial portion flaring radially outwards relative to the cylindrical ventricular portion; anda plurality of replacement leaflets secured to the strut frame.2. The prosthetic mitral valve of claim 1 , wherein the atrial and ventricular anchors are flared radially outwards relative to the central portion claim 1 , and wherein an angle of the flared atrial portion substantially conforms to an angle of the flared atrial anchor.3. The prosthetic mitral valve of claim 1 , wherein an angle of the flared atrial portion is between 60 and 65 degrees relative to a central longitudinal axis of the cylindrical ventricular portion.4. The prosthetic mitral valve of claim 1 , wherein an atrial end of the strut frame is attached to the anchor assembly.5. The prosthetic mitral valve of claim 4 , wherein the cylindrical ventricular portion is spaced away from the anchor assembly.6. The prosthetic mitral valve of claim 4 , wherein the atrial end of the strut frame is attached to the anchor assembly with a plurality of rivets.7. The prosthetic mitral valve of claim 1 , wherein the prosthetic mitral valve is configured to self-expand from a constrained configuration to an ...

Подробнее
05-01-2017 дата публикации

Vascular Repair Devices

Номер: US20170000600A1
Принадлежит:

A vascular repair device includes a tubular graft body and a structural framework having at least two stents. A first stent of the stents is connected to the tubular graft body along an entirety of the first stent and a second of the stents includes a periodically changing shape that defines proximal apices having a first radii of curvature and distal apices having a second radii of curvature that is less than the first radii of curvature. The second stent is connected to the tubular graft body at the distal apices. 1. A vascular repair device comprising:a) a tubular graft body having a proximal end, a distal end, an interior surface and a longitudinal axis; and i) a first stent of the stents having first proximal apices and first apices each adjacent pair of first proximal apices and first distal apices defined by a single strut connecting respective adjacent ones of the first proximal and first distal apices, the first stent connected to the proximal end of the tubular graft body; and', 'ii) a second stent of the stents having second proximal apices and second distal apices, each adjacent pair of second proximal apices and second distal apices defined by a single strut, the second proximal apices having a first radius of curvature and second distal apices having a second radius of curvature that is less than the first radius of curvature, wherein the second stent is a bare stent connected to the proximal end of the tubular graft body at the second distal apices of the second stent and the second distal apices of the second stent nested between the struts and the first proximal apices of the first stent., 'b) a structural framework having at least two stents, wherein2. The vascular repair device of claim 1 , wherein the first stent is connected to the interior surface of the tubular graft body.3. The vascular repair device of claim 1 , wherein the distal apices of the second stent are connected to the interior of the tubular graft body.4. The vascular repair device ...

Подробнее
03-01-2019 дата публикации

DEPLOYMENT OF MULTIPLE BILIARY STENTS

Номер: US20190000652A1
Автор: BARAK Ronny, Einav Elad
Принадлежит: ENDO GI MEDICAL LTD.

Apparatus () is provided for use with a guidewire (). The apparatus includes a guide tube () having a guidewire-engaging portion () and a slit () extending proximally along a wall of the guide tube, from a distal end () of the tube, a proximal end () of the slit being located distally to a proximal end () of the tube. A first stent () surrounds the tube and is advanceable together with the tube into a lumen of a subject, the first stent being slidably advanceable off the distal end of the tube; and a second stent (), proximal to the first stent, surrounding a proximal portion of the tube, and advanceable off the distal end of the tube into the lumen, and placed alongside the first stent subsequently to advancement of the first stent off the distal end of the tube. Other applications are also described. 178-. (canceled)79. A method , comprising:using apparatus including:a guide tube shaped to define (a) a guidewire-engaging portion at a distal portion of the guide tube, and (b) a slit extending proximally along a wall of the guide tube, from a distal end of the guide tube, a proximal end of the slit being located distally to a proximal end of the guide tube,a first stent surrounding the distal portion of the guide tube, anda second stent, proximal to the first stent, surrounding a proximal portion of the guide tube; threading a guidewire through the guide tube, such that, following the threading:(a) the guidewire enters a lumen of the guide tube from a distal-end opening of the guide tube,(b) the guidewire passes through the guidewire-engaging portion of the guide tube,(c) the first stent is constrained from distal motion past the guidewire-engaging portion of the guide tube, due to the guidewire passing through the guidewire-engaging portion,(d) the guidewire passes into the lumen of the guide tube through the slit, and(e) the first stent is constrained from proximal motion past the proximal end of the slit.80. The method according to claim 79 , further comprising: ...

Подробнее
04-01-2018 дата публикации

DELIVERY DEVICE AND METHOD OF DELIVERY

Номер: US20180000619A1
Принадлежит:

A delivery device can provide sequential delivery of a plurality of intraluminal devices held in a compressed state on the delivery device. Delivery platforms on the delivery device can hold an intraluminal device in a compressed position and be positioned between pusher bands that may also be radiopaque markers. A post deployment dilation device can be included. The post deployment dilation device can be a plurality of expansion filaments, a bellows, or a balloon. An intravascular device deployment method can include allowing a self-expanding intravascular device to expand, aligning the post deployment dilation device under the intravascular device, and causing the post deployment dilation device to expand radially to push outward on the intravascular device. 1. A delivery device comprising:an inner shaft configured to receive a self-expanding intraluminal device for deployment from the delivery device into a vessel;an outer sheath positioned about at least a portion of the inner shaft and movable with respect to at least a portion of the inner shaft, the outer sheath having a pre-deployment position in which the self-expanding intraluminal device is at least substantially covered and at least one delivery position in which the self-expanding intraluminal device is uncovered to release the self-expanding intraluminal device from the delivery device; and a balloon attached to the outer sheath of the delivery device, the balloon having a pre-actuated configuration having a pre-deployment diameter and an actuated configuration having a deployment diameter larger than the pre-deployment diameter;', 'at least one inflation fluid lumen in fluid communication with the balloon and extending along at least a portion of the outer sheath;, 'a post deployment dilation device comprisingwherein the post deployment dilation device is configured to apply a radial force to an inner surface of the self-expanding intraluminal device after deployment of the self-expanding intraluminal ...

Подробнее
05-01-2017 дата публикации

ENDOVASCULAR IMPLANT

Номер: US20170000629A1
Принадлежит:

A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent. 1. An intravascular tack , comprising:a self expandable tubular body, having a proximal end, a distal end and a central lumen extending therethrough, the body comprising a plurality of metal struts and having a length of no more than about 15 mm;wherein the tubular body is radially expandable through a range of diameters which range exceeds 3 mm and the change in radial force upon expansion is no more than about 2.5 N at any point in the range.2. An intravascular tack as in claim 1 , wherein the radial force upon expansion changes no more than about 1.5 N throughout the range.3. An intravascular tack as in claim 1 , wherein the range is from about 3 mm to about 6 mm.4. An intravascular tack as in claim 3 , wherein the radial force at both 3 mm and 6 mm is less than 2.0 N.57.-. (canceled)8. A formed in situ intravascular construct claim 3 , comprising a plurality of at least three intravascular tacks each having a length of no more than about 8 mm and spaced apart from an adjacent tack by at least about 2 mm claim 3 , each tack having a radial expansion force of no more than about 4 N.9. An intravascular construct as in claim 8 , comprising at least 5 intravascular tacks.10. An intravascular construct as in claim 8 , wherein each tack has a length of no ...

Подробнее
05-01-2017 дата публикации

METHODS AND SYSTEMS FOR INCREASING A DENSITY OF A REGION OF A VASCULAR DEVICE

Номер: US20170000631A1
Автор: Kusleika Rich
Принадлежит:

A vascular device is provided that includes a mesh structure formed of a plurality of spaced members. The structure has (i) a first, collapsed configuration, (ii) a second, expanded configuration, and (iii) a density of the plurality of members. The vascular device further includes an elastic member disposed along a region of the structure, the region having a proximal end and a distal end. The elastic member is configured to increase the density within the region by drawing at least one of the proximal and distal ends of the region toward the other of the proximal and distal ends when the structure is in the second configuration. 1. A vascular device , comprising:a mesh structure formed of a plurality of spaced members, the structure having (i) a first, collapsed configuration, (ii) a second, expanded configuration, and (iii) a density of the plurality of members; andan elastic film disposed along a region of the structure, the region having a proximal end and a distal end, wherein the elastic film is configured to increase the density within the region by drawing at least one of the proximal and distal ends of the region toward the other of the proximal and distal ends when the structure is in the second configuration.2. The vascular device of claim 1 , wherein the elastic film is disposed on at least one of an inner surface and an outer surface of the structure.3. The vascular device of claim 1 , wherein the elastic film comprises a plurality of pores configured to permit blood to flow therethrough.4. The vascular device of claim 3 , wherein the pores are sized between about 70-200 microns.5. The vascular device of claim 1 , wherein the elastic film is configured to decrease the length of the region by about 10%-40% in the second configuration.6. The vascular device of claim 1 , wherein the elastic film is configured to allow tissue overgrowth thereon.7. The vascular device of claim 1 , wherein the elastic film forms a substantially cylindrical shape.8. The ...

Подробнее
01-01-2015 дата публикации

ENDOVASCULAR PROSTHESIS

Номер: US20150005868A1
Принадлежит: ASSISTANCE PUBLIQUE HOPITAUX DE PARIS

The endovascular prosthesis includes a first expandable framework and a first jacket for the first framework, the first framework and the first jacket forming a first channel when the first framework is in the expanded state. The first framework and the first jacket each have at least one opening, which openings are arranged substantially opposite one another and through which a sleeve is received, the sleeve having a first end and a second end, the perimeter of the first end being attached to the perimeter of the opening of the first jacket, while the second end extends inside the first channel. 1102104100110112200202204114100. Endovascular prosthesis comprising a first expandable framework () and a first jacket () for said first framework , said first framework and said first jacket forming a first channel () when the first framework is in the expanded state , characterised in that the first framework and the first jacket each have at least one opening ( , ) , which openings are arranged substantially opposite one another and through which a sleeve () is received , said sleeve having a first end () and a second end () , the perimeter of said first end being attached to the perimeter () of the opening of the first jacket , while said second end extends inside said first channel ().2102104200202204114100. Endovascular prosthesis according to claim 1 , characterised in that the first expandable framework () and the first jacket () each have a plurality of openings which are arranged substantially opposite one another and through which a sleeve () is received claim 1 , each sleeve having a first end () and a second end () claim 1 , each perimeter of the first ends being attached to each perimeter () of the openings of the first jacket claim 1 , while each second end extends inside said first channel ().3302304300300100200200300. Endovascular prosthesis according to claim 1 , characterised in that it further comprises a second expandable framework () and a second ...

Подробнее
14-01-2016 дата публикации

INTRAVASCULAR STENT WITH HELICAL STRUTS AND SPECIFIC CROSS-SECTIONAL SHAPES

Номер: US20160008149A1
Автор: CHEN Hsin, Hsiao Hao-Ming
Принадлежит:

The present invention relates to a stent, comprising: a plurality of radially-expandable rings arranged along a longitudinal axis, wherein each radially-expandable ring may comprise a plurality of bar arms and a plurality of crowns, and adjacent crowns are connected by the bar arms therebetween; and a plurality of connectors between the radially-expandable rings for connecting such radially-expandable rings; wherein a cross-sectional shape of the bar arms, the crowns or the connectors may comprise helical structures, specific cross-sectional shapes, or a combination thereof. New stent manufacturing techniques, such as the 3D additive printing, could be used for making these proposed stents feasible. 1. A stent , comprising:a plurality of radially-expandable rings arranged along a longitudinal axis, wherein each of the radially-expandable rings comprises a plurality of bar arms and a plurality of crowns, wherein adjacent crowns are connected by the bar arms therebetween; anda plurality of connectors disposed between the radially-expandable rings for connecting the radially-expandable rings;wherein a cross-sectional shape of at least one of the bar arms, the crowns, or the connectors is selected from the group of circular, oval, triangular, rectangular, hexagonal, octagonal, polygonal, and airfoil shapes, or any combination thereof.2. The stent as claimed in claim 1 , wherein at least one of the bar arms claim 1 , the crowns claim 1 , and the connectors comprises a helical structure.3. The stent as claimed in claim 2 , wherein the connectors comprise the helical structures.4. The stent as claimed in claim 2 , wherein the bar arms comprise the helical structures.5. The stent as claimed in claim 3 , wherein the bar arms and the connectors comprise the helical structures.6. The stent as claimed in claim 5 , wherein the bar arms claim 5 , the crowns claim 5 , and the connectors comprise the helical structures.7. The stent as claimed in claim 2 , wherein the helical ...

Подробнее
14-01-2016 дата публикации

STENT AND METHOD FOR MANUFACTURING THEREOF

Номер: US20160008150A1
Автор: Welch Tre Raymond
Принадлежит:

According to one aspect of the present disclosure, a method and technique for manufacturing a stent are disclosed. The stent is a non-metallic stent having a furled small-diameter state and an expanded large-diameter state where the stent, in the furled small-diameter state, includes a plurality of central lobes arranged at spaced-apart intervals and extending longitudinally defining a stent axis, the plurality of central lobes defining a cylindrical plane of the stent. The stent also includes at least one peripheral lobe formed on at least one of the plurality of central lobes, the peripheral lobe oriented along the cylindrical plane. 1. A non-metallic bifurcated stent comprising: an element forming a first plurality of spaced-apart central lobes as the element extends from a proximal end of the stent component to a distal end of the stent component, wherein each of the first plurality of central lobes are formed by a coiled rotation of the element,', 'a second plurality of spaced-apart central lobes formed by the element as the element returns from the distal end to the proximal end of the stent component, wherein each of the second plurality of central lobes are formed by a coiled rotation of the element, wherein the first plurality of central lobes are formed in a non-parallel winding configuration relative to the second plurality of central lobes, and', 'at least one peripheral lobe formed on at least one of the first plurality of central lobes and on at least one of the second plurality of central lobes;, 'a primary stent component and a secondary stent component, wherein each of the primary stent component and the secondary stent component has a furled small-diameter state and an expanded large diameter state, and wherein each of the primary stent component and the secondary stent component comprises, in the furled small-diameter statewherein said primary stent component has a first portion, a second portion and a medial portion located between the first ...

Подробнее
11-01-2018 дата публикации

PROSTHESIS HAVING PIVOTING FENESTRATION

Номер: US20180008397A1
Принадлежит:

The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. 1. A prosthesis , comprising:a graft having a tubular body and a surface comprising a first biocompatible material;at least one fenestration having a diameter extending from a sidewall of the graft;a first perimeter having a first diameter and surrounding the fenestration;a band of flexible material attached to and surrounding the first perimeter and having a flexible frame;a second perimeter attached to and surrounding the band of flexible material and having a second diameter greater than the first perimeter diameter;where the band of material has a first diameter substantially the same as the first perimeter diameter and a second diameter substantially the same as the diameter of the second perimeter, and where the diameter of the band of material decreases in a direction away from the surface of the graft from the second perimeter to the first perimeter; andwhere each fenestration is pivotable in any direction away from an axis perpendicular to a longitudinal axis of the prosthesis.2. The prosthesis of claim 1 , wherein the flexible frame includes a plurality of support units.3. The prosthesis of claim 1 , wherein the band of material has a concave or convex orientation relative to the surface of the graft.4615. The prosthesis of claim 1 , wherein the first diameter of the band is about mm and the second diameter of the band is about mm.5. The prosthesis of claim 5 , wherein the first perimeter claim 5 , the band of material claim 5 , and the second perimeter form a hemispherical shape and are substantially concentric when positioned in the same plane.6. A prosthesis for treatment of a main vessel ...

Подробнее
11-01-2018 дата публикации

Stent

Номер: US20180008439A9
Принадлежит: MicroVention Inc

In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.

Подробнее
11-01-2018 дата публикации

BRANCH ENDOGRAFT DELIVERY

Номер: US20180008442A1
Автор: Douglas Myles
Принадлежит: Red Vascular Technologies, LLC

A system for treating disease involving branching vessels of a mammal system can include a main graft assembly (i) having a lumen permitting fluid flow therethrough, and (ii) configured to expand within a first vessel of a mammal; and a branch graft assembly including a branch cover (i) having a cover lumen permitting fluid flow therethrough; and (ii) configured to expand within a branch vessel that branches from the first vessel. The branch graft assembly may also include an expandable branch stent extending within the cover lumen. The branch graft assembly may further include a branch sheath (i) extending between the branch stent and the cover lumen, and (ii) constraining radial expansion of the branch stent within the cover lumen. 1. (canceled)2. A graft system for treating branching blood vessels of a mammal , said branch assembly comprising:a main graft assembly including a main stent with a main stent lumen and a main cover with a main cover lumen; anda branch graft assembly including a branch stent with a branch stent lumen and a branch cover with a branch cover lumen, wherein the branch cover is coupled with the main cover;a branch sheath (i) positioned fully over the expandable branch stent and beneath the branch cover, and (ii) constraining radial expansion of the branch stent, wherein the expandable branch stent is attached to the branch cover along at least a part of a perimeter of the branch cover in order to inhibit distal movement of the branch sheath within the branch cover lumen while said branch graft assembly is being advanced through a first vessel and into a branch vessel;an outer sheath which constrains the branch graft assembly to lie substantially in parallel against the main graft assembly while the main graft assembly and the branch graft assembly are being advanced through the first vessel;such that (i) retracting the outer sheath from over the main graft assembly and the branch graft assembly laterally releases the branch graft assembly ...

Подробнее
27-01-2022 дата публикации

Coated Stent

Номер: US20220023074A1
Автор: PU Wenjun, XIAO Benhao

A coated stent (), comprises a coated unit (), and an exposed unit () which is a ring-shaped structure and which is provided on the periphery () of an end portion () of the coated unit (); the exposed unit () comprises an inward-tilting wave body (), the inward-tilting wave body () comprising at least a first wave crest () and a first wave rod () connected to the first wave crest (); the position of the first wave crest () is farther away from the coated unit () than other positions on the inward-tilting wave body (); the first wave rod () is planar, and from the first wave crest () to an end of the exposed unit () near the coated unit (), the radial distance from the inward-tilting wave body () to the central axis () of the coated unit () gradually increases. When the coated stent () is implanted into an arterial vessel (), the inward-tilting wave body () forms a certain avoidance space due to the tilt to adapt to the curvature of a large curved side () of the arterial vessel (), and prevents the inward-tilting wave body () from directly piercing a branch vessel (). 1. A covered stent , wherein the covered stent comprises:a covered unit; anda bare unit, which is a ring-shaped structure and arranged on a periphery of an end portion of the covered unit, wherein the bare unit comprises an inward-tilting wave body comprising at least a first wave crest and a first wave rod connected to the first wave crest, the first wave crest is further from the covered unit than other positions of the inward-tilting wave body, the first wave rod is planar, and from the first wave crest to an end of the bare unit close to the covered unit, a radial distance from the inward-tilting wave body to a central axis of the covered unit gradually increases.2. The covered stent according to claim 1 , wherein the inward-tilting wave body further comprises a first wave trough claim 1 , a vertex of the first wave trough is located on the periphery of the end portion of the covered unit close to ...

Подробнее
27-01-2022 дата публикации

METHOD AND SYSTEM FOR DELIVERING A SELF-EXPANDING STENT TO THE VENOUS SINUSES

Номер: US20220023079A1
Автор: Callister Jeffrey P.
Принадлежит:

A stent delivery system includes a shaft extending from a proximal end of the system into a delivery tip at a distal end. The shaft includes a coil and a stent bed. A stent is loaded onto the stent bed and has a first portion at its distal end having a greater flexibility than a second portion at its proximal end. Sheathing is movable over the stent bed between pre-deployed and deployed positions. The sheathing includes a flexible section at the sheathing distal end, a semi-flexible section adjacent the flexible section, and a stiff section adjacent the semi-flexible section. The delivery tip is more flexible than the combination of the stent bed, the first portion of the stent, and the flexible section of the sheathing, which is more flexible than the combination of the stent bed, the second portion the stent, and the flexible section of the sheathing. 120-. (canceled)21. A method comprising: a delivery handle at a proximal end of the stent delivery system;', 'a catheter hub;', 'a delivery tip at a distal end of the stent delivery system, wherein the delivery tip comprises a tip distal end and a tip proximal end, and wherein the delivery tip has a first flexibility;', 'a shaft extending from the delivery handle through the catheter hub and into the delivery tip, wherein the shaft comprises a coil and a stent bed, the coil having a coil distal end and a coil proximal end, the stent bed between the coil distal end and the tip proximal end;', 'a stent loaded on to the stent bed, wherein the stent comprises a stent distal end, a stent proximal end, and a body between the stent distal end and the stent proximal end, the body defining a lumen extending through the stent from the stent distal end to the stent proximal end in a deployed state, and wherein a first portion of the body at the stent distal end has a greater flexibility than a second portion of the body at the stent proximal end; and', 'sheathing coupled to the catheter hub and movable over the stent bed ...

Подробнее
10-01-2019 дата публикации

Delivery of medical devices

Номер: US20190008668A1
Принадлежит: COVIDIEN LP

A stent delivery system can include a core member, an introducer sheath, and a microcatheter. The core member can have a distal segment. The stent engagement member can have a generally tubular body positioned about the core member distal segment and can be rotatably coupled to the core member. The engagement member can include an inner layer that has a first durometer and an outer layer that has a second durometer less than the first durometer. The stent can extend along the core member distal segment such that an inner surface of the stent is engaged by the engagement member outer layer for facilitating rotation of the stent relative to the core member.

Подробнее
21-01-2016 дата публикации

METHODS AND DEVICES FOR TREATMENT OF VASCULAR DEFECTS

Номер: US20160015396A1
Принадлежит: SEQUENT MEDICAL, INC.

Devices for treatment of a patient's vasculature are described. The device includes a first hub, a second hub, a support structure including a plurality of struts disposed between the first hub and the second hub, and a layer of material disposed over the plurality of struts. The support structure has a low profile, radially constrained state with an elongated tubular configuration suitable for delivery from a microcatheter. The support structure also has an expanded state, a smooth outer surface, and has an axially shortened configuration relative to the radially constrained state. The layer of material may be made from acrylic, silk, silicone, polyvinyl alcohol, polypropylene, polyester, PolyEtherEther Ketone (PEEK), polytetrafluoroethylene (PTFE), polycarbonate urethane (PCU), or polyurethane (PU). The support structure may be formed from a slotted tubular member. 1. A device for treatment of a patient's vasculature comprising:a first hub;a second hub;a support structure having a longitudinal axis and disposed between the first hub and the second hub, the support structure including a plurality of struts; anda layer of material disposed over the plurality of struts,wherein the support structure has a low profile, radially constrained state with an elongated tubular configuration having a transverse dimension, the radially constrained state having a low profile suitable for delivery from a microcatheter, andwherein the support structure also has an expanded state having a first end, a second end, and a smooth outer surface and having an axially shortened configuration relative to the radially constrained state.2. The device of claim 1 , wherein the layer of material comprises at least one of acrylic claim 1 , silk claim 1 , silicone claim 1 , polyvinyl alcohol claim 1 , polypropylene claim 1 , polyester claim 1 , PolyEtherEther Ketone (PEEK) claim 1 , polytetrafluoroethylene (PTFE) claim 1 , polycarbonate urethane (PCU) and polyurethane (PU).3. The device of claim ...

Подробнее
21-01-2016 дата публикации

STENT

Номер: US20160015534A1
Принадлежит: TERUMO KABUSHIKI KAISHA

A stent which improves safety by allowing a living body to be less affected even if a drug is detached. A stent has a strut that is formed in a linear shape, and that defines a cylindrical shape having an opening, a side surface coating member which coats at least a part of at least one of the side surfaces of the strut, the side surface coating member including a drug and a drug loading member which is a polymeric material for loading the drug, and an outer surface coating member which coats at least a part of the outer surface of the strut, the outer surface coating member including the drug without including the drug loading member.

Подробнее
21-01-2016 дата публикации

STENT WITH POLYMER COATING CONTAINING AMORPHOUS RAPAMYCIN

Номер: US20160015537A1
Принадлежит: MICELL TECHNOLOGIES, INC.

A coated coronary stent, comprising a stainless steel sent framework coated with a p1imer layer of Parylene C, and a rapamycin-polymer coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially unifom1ly dispersed within the rapamycin-polymer coating.

Подробнее
18-01-2018 дата публикации

Tubular Structures with Variable Support

Номер: US20180015257A1
Принадлежит: Q'apel Medical LLC

A tubular structure having variable support includes a tubular member and a structural support member with a flexible tubular member over the structural support member, such that the flexible tubular member can engage and disengage or squeeze and release the structural support member. The structural support member can be a tubular mesh, stent, framework, skeleton, braid or other flexible framework. A fluid passage can be used to inflate and deflate the flexible tubular member. Methods of assembly and methods of use are also described.

Подробнее
17-01-2019 дата публикации

ENDOLUMINAL DEVICE

Номер: US20190015230A1
Автор: TRENDEL GARY, Walsh Kevin
Принадлежит: BOSTON SCIENTIFIC SCIMED, INC.

The present invention relates to an endoluminal device for implantation in a body lumen, such as a pancreatic duct. The device is provided with a distal end region having greater flexibility than that of a medial region of the device. 1. An endoluminal device comprising:a stent having a proximal terminal end and a distal terminal end and a longitudinal axis extending therebetween, the stent formed from a plurality of wires;wherein a distal end region adjacent the distal terminal end includes a plurality of loops formed by the plurality of wires, each loop being formed by an end region of a first wire of the plurality of wires connected to an end region of a second wire of the plurality of wires at a joining region, each joining region including only two wires, each loop having only one joining region, each loop having straight side portions, wherein the joining region is proximal of the distal terminal end and distal of the straight side portions.2. The endoluminal device of claim 1 , wherein the first wire extends to the distal terminal end of the stent and is bent back toward the proximal terminal end to form a distal tip of the loop that defines the distal terminal end of the stent.3. The endoluminal device of claim 1 , wherein there is no contact between adjacent straight side portions of adjacent loops.4. The endoluminal device of claim 1 , wherein each of the plurality of loops in the distal end region circumferentially overlaps two adjacent loops of the plurality of loops in the distal end region.5. The endoluminal device of claim 1 , wherein at least one of the first and second wires forming each of the loops in the distal end region crosses over and/or under two other loops of the plurality of loops in the distal end region.6. The endoluminal device of claim 1 , wherein each of the plurality of loops in the distal end region is interbraided with two adjacent loops of the plurality of loops in the distal end region.7. The endoluminal device of claim 1 , ...

Подробнее
16-01-2020 дата публикации

Replacement Mitral Valves

Номер: US20200015964A1
Принадлежит:

A prosthetic mitral valve includes an anchor assembly, a strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The ventricular anchor and the atrial anchor are configured to flare radially outwards relative to the central portion. The annular strut frame is disposed radially within the anchor assembly and is attached to the anchor assembly. The central portion is configured to align with a native valve orifice and the ventricular anchor and the atrial anchor are configured to compress native cardiac tissue therebetween. 1an anchor assembly comprising a ventricular anchor, an atrial anchor, and a central portion therebetween, wherein the ventricular anchor and the atrial anchor are configured to flare radially outwards relative to the central portion;an annular strut frame disposed radially within the anchor assembly, the annular strut frame attached to the anchor assembly at a plurality of attachment locations that are positioned between the central portion and an atrial-most edge of the anchor assembly; anda plurality of replacement leaflets secured to the annular strut frame;wherein the central portion is configured to align with a native valve orifice and the ventricular anchor and the atrial anchor are configured to compress native cardiac tissue therebetween.. A prosthetic mitral valve comprising: This application is a continuation of U.S. patent application Ser. No. 15/908,701, filed Feb. 28, 2018, which is a continuation of International Patent Application No. PCT/US2018/14902, filed Jan. 23, 2018, titled “REPLACEMENT MITRAL VALVES”, which claims priority to U.S. Provisional Application No. 62/513,877, filed Jun. 1, 2017 and to U.S. Provisional Patent Application No. 62/449,498, filed Jan. 23, 2017, and titled “REPLACEMENT MITRAL VALVES,” the entireties of which are hereby incorporated by reference herein.U.S. patent ...

Подробнее
28-01-2016 дата публикации

SYSTEMS FOR DIAGNOSING AND/OR TREATING MEDICAL CONDITIONS

Номер: US20160022222A1
Принадлежит:

A method for performing a diagnostic or therapeutic procedure on a partial occlusion within a blood vessel, includes positioning a guide having a sensor configured and adapted to measure at least one of pressure, volume or flow within a blood vessel, advancing the guide through an at least partial occlusion within the blood vessel such that the sensor is downstream of the occlusion, measuring at least one of pressure, volume or flow downstream of the occlusion using the sensor and analyzing data obtained from the sensor to assist in determining the viability of tissue of the blood vessel downstream of the occlusion. 1. A method for performing a diagnostic or therapeutic procedure on an occlusion within a blood vessel , the method comprising:positioning a guide having a sensor configured and adapted to measure at least one of pressure, volume or flow within a blood vessel;advancing the guide through an at least partial occlusion within the blood vessel such that the sensor is downstream of the occlusion;measuring at least one of pressure, volume or flow downstream of the occlusion using the sensor; andanalyzing data obtained from the sensor to assist in determining the viability of tissue of the blood vessel downstream of the occlusion.2. The method according to including determining a surgical protocol based on analyzing the data.3. The method according to including obtaining a CT scan of the blood vessel and/or the occlusion wherein determining the surgical protocol includes reviewing the CT scan.4. The method according to including treating the occlusion.5. The method according to wherein treating the occlusion includes at least one of introducing a thrombectomy device to remove the occlusion claim 4 , initiating drug therapy to treat the occlusion or implanting a flow diverter adjacent the occlusion.6. The method according to wherein measuring at least one of pressure claim 4 , volume or flow downstream of the occlusion using the sensor is also performed ...

Подробнее
28-01-2016 дата публикации

ENDOLUMINAL PROSTHESIS HAVING MULTIPLE BRANCHES OR FENESTRATIONS AND METHODS OF DEPLOYMENT

Номер: US20160022411A1
Принадлежит:

A system for facilitating deployment of an endoluminal prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. A wire segment may include a proximal portion positioned proximal of the proximal end opening and a distal portion positioned distal of the distal end opening. The wire segment extend through the fenestration and through the lumen of the branch in a preloaded configuration. 1. A branched prosthesis comprising:a tubular body of biocompatible graft material having a proximal end, a distal end, an internal lumen, and a longitudinal axis from the proximal end to the distal end;a proximal portion having a first diameter;a distal portion having a second diameter less than the first diameter;a tapered portion between the proximal portion and the distal portion;a retrograde portal at least partially disposed in the distal portion having an opening and configured to permit retrograde fluid flow therethrough;at least two antegrade portals at least partially disposed in the proximal portion each having an open end extending toward the distal end and configured to permit antegrade fluid flow therethrough.2. The prosthesis of claim 1 , wherein the retrograde portal and the at least two antegrade portals are configured to receive a branch extension.3. The prosthesis of claim 1 , wherein one or more radiopaque markers is positioned proximate to one or more of the portals to facilitate imaging of the one or more portals.4. The prosthesis of claim 2 , wherein the branch extensions are balloon expandable.5. The prosthesis of claim 5 , wherein the branch extensions are covered balloon expandable stents.6. The prosthesis of claim 1 , wherein the open ends of the antegrade portals are ...

Подробнее
28-01-2016 дата публикации

LOCKING MECHANISM FOR SECURING THE INTERFACE BETWEEN STENT GRAFTS

Номер: US20160022413A1
Автор: Farag Jacqueline
Принадлежит: Cook Medical Technologies LLC

A modular stent graft system and methods of assembly are disclosed. The stent graft assembly comprises a first stent graft having an interface region at its distal end and a first locking stent secured to an internal surface of the interface region. A second stent graft having an interface region at its proximal end is configured to at least partially overlap with the interface region at the distal end of the first stent graft. The second stent graft comprises a second locking stent secured to an external surface of the interface region. The first and second locking stents are configured to be engaged such that the second locking stent is nested between the first locking stent and an internal surface of the interface region of the first stent graft thereby interlocking the first and second stent grafts to each other. 1. A modular stent graft system comprisinga first stent graft comprising a first tubular body of biocompatible graft material, a proximal end, a distal end, an internal lumen, and an inner interface region at the distal end having an internal surface;a locking stent secured to the internal surface of the inner interface region, the locking stent having a first end, a second end, proximal apices, distal apices, and a locking mechanism at one of the ends of the locking stent having an unattached free end that extends away from the internal surface and inwardly into the internal lumen;a second stent graft comprising a second tubular body of biocompatible graft material, a proximal end, a distal end, and an outer interface region having an external surface at the proximal end configured to at least partially overlap with the inner interface region of the first stent graft;at least one stent secured to the external surface of the outer interface region, the at least one stent comprising a series of proximal apices and a series of distal apices, wherein when the inner interface region and outer interface region are in at least a partial overlapping ...

Подробнее
28-01-2016 дата публикации

Occlusive Device

Номер: US20160022445A1
Принадлежит: COVIDIEN LP

An aneurysm embolization device can include a body having a single, continuous piece of material that is shape set into a plurality of distinct structural components. For example, the device can have an expandable component and an atraumatic tip portion extending therefrom. Further, the tip portion can be configured to enable the device to be implanted within the aneurysm while tending to mitigate risk of puncturing the aneurysm dome or otherwise assist in framing the aneurysm in advance of placement of additional embolic material.

Подробнее
28-01-2016 дата публикации

VASCULAR DEVICE FOR ANEURYSM TREATMENT AND PROVIDING BLOOD FLOW INTO A PERFORATOR VESSEL

Номер: US20160022451A1
Автор: Kusleika Richard
Принадлежит:

A vascular device includes a body having a first, collapsed configuration and a second, expanded configuration. The body includes a plurality of heat-set strands that are braided such that when the body is in the second configuration, the strands form a plurality of pores and one or more apertures between the strands. The apertures are generally disposed at a longitudinal center region of the body. When the body is in the second configuration, the pores at proximal and distal portions of the body are generally uniform in size and smaller in size than the apertures. The pores and the apertures are substantially the same size when the body is in the first configuration. 1. A method , comprising:positioning, at a target location within a blood vessel, a vascular device having a body in a first, collapsed configuration with the body comprising braided strands forming pores and apertures between the strands, the pores and the apertures being substantially the same size as each other in the first, collapsed configuration; andexpanding the body from the first, collapsed configuration to a second, expanded configuration with the apertures being disposed at a longitudinally central section of the body, the pores being disposed at longitudinally proximal and distal sections of the body, and the pores being generally uniform in size and smaller in size than the apertures in the second, expanded configuration;wherein a number of strands in each of the proximal, central, and distal sections of the body is the same.2. The method of claim 1 , wherein central regions of the apertures are disposed along a single radial cross section of the body.3. The method of claim 2 , wherein the body has a hoop strength that is generally uniform along a longitudinal length of the body.4. The method of claim 1 , wherein the body has a hoop strength that is generally uniform along a longitudinal length of the body.5. The method of claim 1 , wherein the expanding comprises aligning at least one of ...

Подробнее
26-01-2017 дата публикации

STENT AND METHOD FOR MANUFACTURING THEREOF

Номер: US20170020699A1
Автор: Welch Tre Raymond
Принадлежит:

According to one aspect of the present disclosure, a method and technique for manufacturing a stent are disclosed. The stent is a non-metallic stent having a furled small-diameter state and an expanded large-diameter state where the stent, in the furled small-diameter state, includes a plurality of central lobes arranged at spaced-apart intervals and extending longitudinally defining a stent axis, the plurality of central lobes defining a cylindrical plane of the stent. The stent also includes at least one peripheral lobe formed on at least one of the plurality of central lobes, the peripheral lobe oriented along the cylindrical plane. 1. A non-metallic stent having a furled small-diameter state and an expanded large diameter state , the stent comprising , in the furled small-diameter state:a first plurality of central lobes arranged at spaced-apart intervals and extending longitudinally defining a stent axis;a second plurality of central lobes arranged at spaced-apart intervals and extending longitudinally along the stent axis;at least one peripheral lobe formed on at least one of the first plurality of central lobes and on at least one of the second plurality of central lobes, each lobe of the first plurality of central lobes, the second plurality of central lobes, and the at least one peripheral lobe formed by a coiled rotation of an element, wherein the element comprises a Poly-L-Lactic Acid polymer fiber loaded with a material; andwherein the first plurality of central lobes are formed longitudinally in a first direction along said stent axis in a rotational winding direction and the second plurality of central lobes are formed longitudinally in a second direction along said stent axis in the rotational winding direction to form respective first and second helices having an opposing winding pattern along the stent axis.2. The stent of claim 1 , wherein said material is a radio-opaque material.3. The stent of claim 1 , wherein the at least one peripheral lobe ...

Подробнее
24-01-2019 дата публикации

STENT WITH EXPANDABLE FOAM

Номер: US20190021838A1
Принадлежит:

A stent for treating a physical anomaly. The stent includes a skeletal support structure for expanding in the physical anomaly and a shape memory material coupled to the skeletal support structure. 1. A system comprising:a first shape memory polymer (SMP), the first SMP including a first SMP foam;a second SMP, the second SMP including a second SMP foam;wherein the first SMP foam: (a)(i) is an open cell foam, (a)(ii) is biodegradable, (a)(iii) includes a first channel, and (a)(iv) includes two or more members selected from the group comprising Hexamethylene diisocyanate (HDI), triethanolamine (TEA), or hydroxypropyl ethylenediamine (HPED);wherein the second SMP foam: (b)(i) is cylindrical, (b)(ii) includes a second channel, and (b)(iii) is included in the first channel; andwherein: (c)(i) the first SMP foam is in a first state; and (c)(ii) the first SMP foam is configured to expand to a second state, radially outward from the second SMP foam, in response to thermal stimulus.2. The system of wherein:{'sub': 'g', 'the first SMP foam has a glass transition temperature (T) between 30° C. and 86° C.;'}the first SMP foam is cross-linked; andthe first SMP foam is configured to have, in the second state, a volumetric void fraction greater than 98% and less than 100%.3. The system of comprising a third SMP claim 2 , wherein the third SMP is between the first and second SMP foams.4. The system of wherein the third SMP includes a stent having a first strut that includes the third SMP and a second strut that includes the third SMP.5. The system of comprising a fourth SMP claim 3 , wherein:the third SMP is between the fourth SMP and the second SMP;the second SMP is not monolithic with the first SMP;the second SMP is not monolithic with the third SMP;the fourth SMP is not monolithic with the second SMP;the fourth SMP is cured.6. The system of comprising a third SMP claim 2 , wherein:the second SMP foam is between the third SMP and the first SMP foam;the third SMP is cured and the ...

Подробнее
24-01-2019 дата публикации

FLEXIBLE STENT WITH NON-BONDED STENT COVER MATERIAL REGIONS

Номер: US20190021840A1
Принадлежит: Cook Medical Technologies LLC

A prosthesis is provided for a variety of medical treatments. The prosthesis may include an expandable tubular frame structure and a covering disposed along the frame structure. A proximal liner may be situated along a proximal end of the frame, a distal liner may be situated along a distal end of the frame, and an intermediate liner may be between the proximal liner and the distal liner along the frame. The intermediate liner comprises an extended layer that meets and bonds to the proximal liner and the distal liner at their respective ends. A method of manufacturing the prosthesis is also provided. 1. A prosthesis comprising:an expandable tubular frame structure having a proximal frame end and a distal frame end;a covering disposed along the frame structure, the covering including a first liner, a proximal liner, and a distal liner discrete from the proximal liner, the first liner comprising a plurality of first liner layers, wherein at least one of the first liner layers is an extended layer extending beyond a proximal end of the remaining first liner layers and a distal end of the remaining first liner layers of the first liner,wherein a proximal end of the extended layer is bonded to the proximal liner along the proximal frame end at a first coupling segment, and a distal end of the extended layer is bonded to the distal liner along the distal frame end at a second coupling segment, andwherein one of the first liner layers immediately adjacent to the expandable tubular frame structure remains unbonded to the expandable tubular frame structure along an intermediate region of the frame structure disposed between the proximal and distal frame ends.2. The prosthesis of claim 1 , wherein the first and second coupling segments have a common wall thickness claim 1 , and an intermediate segment of the first liner that remains unbonded to the expandable tubular frame structure comprises a wall thickness sized the same as the common wall thickness.3. The prosthesis of ...

Подробнее
24-01-2019 дата публикации

STENT WITH SEGMENTS CAPABLE OF UNCOUPLING DURING EXPANSION

Номер: US20190021885A1
Принадлежит: Cook Medical Technologies LLC

Examples of a stent are provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment. 1. A stent disposed about a longitudinal axis , the stent having a radially compressed configuration and a radially expanded configuration , the stent comprising:a first stent segment disposed about the longitudinal axis and a plurality of stent struts forming a plurality of first outer apices that extend in a first longitudinal direction;a second stent segment disposed about the longitudinal axis and axially to adjacent to the first stent segment, the second stent segment having a plurality of stent struts forming a plurality of second outer apices that extend in a second longitudinal direction, opposite the first longitudinal direction; anda plurality of interlocking joints removably coupling the first stent segment and the second stent segment together, each of the interlocking joints comprising is a first mating element, a second mating element, and a third mating element, wherein the first mating element extends away from one of the first outer apices, the second mating element and the third mating element extend away from adjacent outer apices of the second outer apices, and an axial restrictor member extending away from the second stent segment, wherein, in the radially compressed configuration, the second and third mating elements are circumferentially engageable with the first mating element, and the axial restrictor member is axially engageable with the first mating element.2. The stent of claim 1 , wherein the axial restrictor member ...

Подробнее
24-01-2019 дата публикации

SEGMENTED SELF-EXPANDING STENT

Номер: US20190021886A1
Принадлежит:

Disclosed herein is a delivery system and method for delivering a plurality of separate intraluminal support devices with predictable spacing. The intraluminal support devices may be self-expanding devices mounted over an inflatable balloon of a balloon catheter and adhered thereto by an adhesive. The intraluminal support devices may optionally have a flattened tip region. 1. A medical device assembly comprising:a balloon catheter comprising a catheter body extending from a proximal end to a distal end and defining a longitudinal axis therethrough, and a balloon inflatable from a deflated state to an inflated state disposed circumferentially around the catheter body; anda plurality of separate intraluminal support devices for implantation into a lumen of a body vessel, each intraluminal support device comprising a tubular body comprising at least one ring and being radially expandable from a compressed state to an expanded state, each intraluminal support device being a self-expanding device;the plurality of intraluminal support devices being releasably secured about a delivery portion of the balloon in the deflated state, the plurality of intraluminal support devices being arranged such that a portion of one of the intraluminal support devices is in contact with a portion of an adjacent intraluminal support device, the plurality of intraluminal support devices being detached from the balloon when in the inflated state.2. The medical device assembly of claim 1 , wherein each ring comprises a plurality of struts and bends arranged in a repeating pattern to define a plurality of peaks.3. The medical device assembly of claim 2 , wherein each of the plurality of peaks defines a flat surface in a plane perpendicular to the longitudinal axis.4. The medical device assembly of claim 2 , wherein the plurality of peaks of one intraluminal support device are arranged in phase with the plurality of peaks of an adjacent intraluminal support device.5. The medical device assembly ...

Подробнее
23-01-2020 дата публикации

DEVICES AND METHODS FOR TREATMENT OF VASCULAR ANEURYSMS

Номер: US20200022801A1
Принадлежит:

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm. 1. A system for treating an aneurysm comprising:a catheter delivery system having a distal tip; anda filler passable through the distal tip, wherein when the filler is in a deployed configuration, the filler is between a first leg of a bifurcated stent and a wall of the aneurysm, and wherein when the filler is in the deployed configuration, the filler is between a second leg of the bifurcated stent and the wall of the aneurysm.2. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler contacts the first and second legs of the bifurcated stent.3. The system of claim 2 , wherein when the filler is in the deployed configuration claim 2 , the filler contacts the wall of the aneurysm.4. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler contacts the wall of the aneurysm.5. The system of claim 4 , wherein when the filler is in the deployed configuration claim 4 , the filler contacts at least one of the first and second legs of the bifurcated stent.6. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , a portion of the filler is between ...

Подробнее
23-01-2020 дата публикации

DEVICES AND METHODS FOR TREATMENT OF VASCULAR ANEURYSMS

Номер: US20200022802A1
Принадлежит:

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In one embodiment, a system for treating an aneurysm is disclosed. The system comprises a catheter delivery system, an expandable foam configured to pass through the catheter delivery system, and a stent having a first end and a second end. The stent is configured to extend across the aneurysm. The expandable foam is configured to expand in the aneurysm when exposed to a fluid. 1. A system for treating an aneurysm comprising:a catheter delivery system having a distal tip; anda filler passable through the distal tip into a first fillable space and into a second fillable space, wherein when the filler is in a deployed configuration, the filler is in the first and second fillable spaces, and wherein the first fillable space is at a proximal end of the aneurysm and the second fillable space is at a distal end of the aneurysm.2. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the ii first fillable space and the second fillable space are separate from each other.3. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the first fillable space is connected to the second fillable space.4. The system of claim 1 , wherein before the filler is deployed claim 1 , the first fillable space is separate from the second fillable space.5. The system of claim 4 , wherein after the filler is deployed claim 4 , the first fillable space is connected to the second fillable space.6. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler is a continuous structure.7. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler contacts two distal legs of a bifurcated stent.8. The system of claim 7 , wherein when the filler is in the ...

Подробнее
28-01-2021 дата публикации

STENT WITH EXPANDABLE FOAM

Номер: US20210022847A1
Принадлежит:

A stent for treating a physical anomaly. The stent includes a skeletal support structure for expanding in the physical anomaly and a shape memory material coupled to the skeletal support structure. 1a first shape memory polymer (SMP), the first SMP including a SMP foam;a second SMP;wherein the SMP foam: (a)(i) is an open cell foam, (a)(ii) is biodegradable, (a)(iii) includes a first channel, and (a)(iv) includes a reaction product of a diisocyanate, triethanolamine (TEA), and hydroxypropyl ethylenediamine (HPED);wherein the second SMP: (b)(i) is a cylindrical stent having a first strut that includes the second SMP and a second strut that includes the second SMP, (b)(ii) includes a second channel, and (b)(iii) is included in the first channel;wherein: (c)(i) the SMP foam is in a first state; and (c)(ii) the SMP foam is configured to expand to a second state, radially outward from the second SMP, in response to thermal stimulus;wherein the first SMP is crimped and the second SMP is crimped;wherein the SMP foam has a glass transition temperature (Tg) between 30° C. and 86° C.;wherein the SMP foam is a thermoset polyurethane polymer;wherein the first SMP is coupled to a wire and the second SMP is coupled to the wire.. A system comprising: This application is a Continuation of U.S. patent application Ser. No. 16/139,365, filed Sep. 24, 2018, which is a Continuation of U.S. patent application Ser. No. 14/797,973, filed Jul. 13, 2015, entitled “Stent with Expandable Foam”, which issued on Sep. 25, 2018 as U.S. Pat. No. 10,080,642, which is a Continuation of U.S. patent application Ser. No. 13/892,492, filed May 13, 2013, entitled “Stent with Expandable Foam”, which issued on Jul. 14, 2015 as U.S. Pat. No. 9,078,738, which is a continuation of U.S. patent application Ser. No. 13/010,055, filed Jan. 20, 2011, entitled “Stent with Expandable Foam”, which issued on May 28, 2013 as U.S. Pat. No. 8,449,592, which is a Continuation-in-Part of U.S. patent application Ser. No. 11/ ...

Подробнее
28-01-2021 дата публикации

APPARATUS AND METHOD FOR DEPLOYING AN IMPLANTABLE DEVICE WITHIN THE BODY

Номер: US20210022897A1
Принадлежит: Taheri LaDuca LLC

The present invention provides systems and methods for deploying implantable devices within the body. The delivery and deployment systems include at least one catheter or an assembly of catheters for selectively positioning the lumens of the implant to within target vessels. Various deployment and attachment mechanisms are provided for selectively deploying the implants. 1. A stent-loaded catheter assembly as disclosed herein.2. A method of deploying a stent as disclosed herein. This application is a continuation of U.S. patent application Ser. No. 16/116,750 filed Aug. 29, 2018, which is a continuation of U.S. patent application Ser. No. 12/240,833 filed Sep. 29, 2008 (now U.S. Pat. No. 10,105,249), which is a continuation of International Application No. PCT/US2008/053615 filed Feb. 11, 2008, which claims the benefit of U.S. Provisional Application No. 60/889,186 filed Feb. 9, 2007. U.S. patent application Ser. No. 12/240,833 is also a continuation-in-part of U.S. patent application Ser. No. 11/033,479 filed Jan. 10, 2005. The contents of these applications are incorporated herein by reference in their entirety for all purposes.The present invention relates to the treatment of vascular disease, including for example aneurysms, ruptures, psuedoaneurysms, dissections, exclusion of vulnerable plaque and treatment of occlusive conditions, and more particularly, the invention is related to an apparatus and method for delivering and deploying an implantable device within the body to treat such conditions. The present invention is particularly suitable for implanting stents, grafts and stent grafts within arteries or other vessels at sites involving two or more intersecting vessels.It is well known in the prior art to treat vascular disease with implantable stents and grafts. For example, it is well known in the art to interpose within a stenotic or occluded portion of an artery a stent capable of self-expanding or being balloon-expandable. Similarly, it is also well ...

Подробнее
10-02-2022 дата публикации

METHOD FOR TREATING ARTERIAL STENOSIS

Номер: US20220044393A1
Принадлежит:

Disclosed herein is a method of treating a subject having arterial stenosis. The method comprises: (a) providing a plurality of image frames of an artery of the subject taken in sequence; (b) in a plurality of cross-sections of the artery, determining a maximum diameter and a minimum diameter of each of the plurality of cross-sections of the artery among the plurality of image frames of the step (a); (c) calculating an average vasodilation ratio of the artery base on the maximum diameter and the minimum diameter determined in the step (b); and (d) treating the subject based on the average vasodilation ratio calculated in the step (c), by implanting a stent to the subject when the average vasodilation ratio is equal to or greater than 0.2; or administering to the subject an effective amount of a vasodilator when the average vasodilation ratio is less than 0.2. 1. A method of treating a subject having arterial stenosis , comprising ,(a) providing a plurality of image frames of an artery of the subject taken in sequence;(b) in a plurality of cross-sections of the artery, determining a maximum diameter and a minimum diameter of each of the plurality of cross-sections of the artery among the plurality of image frames of the step (a);(c) calculating an average vasodilation ratio of the artery base on the maximum diameter and the minimum diameter of each of the plurality of cross-sections of the artery determined in the step (b); and 'implanting a stent to the subject when the average vasodilation ratio is equal to or greater than 0.2.', '(d) treating the subject based on the average vasodilation ratio calculated in the step (c) by'}2. The method of claim 1 , wherein in the step (b) claim 1 , the maximum diameter and the minimum diameter are determined by the steps of claim 1 ,(i) determining a boundary and a central axis of the artery via aligning each of the plurality of image frames;(ii) selecting the plurality of cross-sections in the artery according to the normal ...

Подробнее
01-02-2018 дата публикации

AIRWAY STENT

Номер: US20180028306A1
Принадлежит:

A stent comprising: two or more stent sections; one or more rods extending between the two or more stent sections; wherein one the one or more rods is fixedly connected to a fixed anchor that is connected to a first of the two or more stent sections, and a second of the two or more of stent sections are movable connected to one of the one or more rods by a movable anchor; and wherein the stent supports an opening of an anatomical passageway. 1. A stent comprising:two or more stent sections;a plurality of struts connected to each of the two or more stent sections,one or more rods extending between the two or more stent sections;wherein a first of the two or more stent sections are fixedly connected to one of the one or more rods by a fixed anchor, and a second of the two or more of stent sections are movably connected to one of the one or more rods by a movable anchor;wherein the plurality of struts extend outward away from the one or more rods to support an opening of an anatomical passageway; andwherein the movable anchor allows the second of the two or more stent sections to longitudinally slide along a longitudinal axis of the stent with respect to the first of the two or more stent struts as the plurality of struts expand outward from a retracted state to a deployed state.2. The stent of claim 1 , wherein the first of the two or more stent sections is connected to a first rod of the one or more rods and the second of the two or more stent struts is connected to a second rod of the one or more rods and a hinge point is located between the first rod and the second rod.3. (canceled)4. The stent of claim 1 , wherein the stent is compacted into a cartridge claim 1 , a catheter claim 1 , or both prior to insertion.5. The stent of claim 1 , wherein the stent includes a removal rod.6. The stent of claim 1 , wherein the one or more rods include a stop for each of the two or more stent sections so that each of the two or more stent sections are retained on the one or more ...

Подробнее
24-04-2014 дата публикации

Flexible vascular occluding device

Номер: US20140114342A1
Принадлежит: COVIDIEN LP

A vascular occluding device for modifying blood flow in a vessel, while maintaining blood flow to the surrounding tissue. The occluding device includes a flexible, easily compressible and bendable occluding device that is particularly suited for treating aneurysms in the brain. The neurovascular occluding device can be deployed using a micro-catheter. The occluding device can be formed by braiding wires in a helical fashion and can have varying lattice densities along the length of the occluding device. The occluding device could also have different lattice densities for surfaces on the same radial plane.

Подробнее
17-02-2022 дата публикации

MEDICAL DEVICE, IN PARTICULAR A FLOW DIVERTER, AND KIT

Номер: US20220047373A1
Принадлежит:

The invention concerns a medical device, in particular a flow diverter, having a radially self-expandable lattice structure () which is tubular at least in some regions and which is composed of a plurality of interwoven individual wires () which form meshes () of the lattice structure (), wherein at least some of the individual wires () have an X-ray visible core material () and a superelastic mantle material (), wherein a plurality of directly adjacent meshes () in the circumferential direction of the lattice structure () form a mesh ring (), wherein in a fully self-expanded state, the lattice structure () has an expansion diameter D, the mesh ring () has a mesh number n, and the core material () has a core diameter d, and wherein for the core diameter d, the following holds: 2. The medical device as claimed in claim 1 ,characterized in that{'sub': 'exp', '#text': 'the expansion diameter Dis 2.5 mm to 8 mm.'}3. The medical device as claimed in one of the preceding claims claim 1 ,characterized in that{'b': '10', '#text': 'a braiding angle α of the lattice structure () is between 70° and 80°, in particular 75°.'}4. The medical device as claimed in one of the preceding claims claim 1 ,characterized in that{'b': '11', 'sub': 'wire', 'claim-text': [{'sub': ['exp', 'wire'], '#text': 'in the case of an expansion diameter Dof 2.5 mm to 4.5 mm: 30 μm≤d≤46 μm, and'}, {'sub': ['exp', 'wire'], '#text': 'in the case of an expansion diameter Dof more than 4.5 mm to 8 mm: 46 μm≤d≤65 μm.'}], '#text': 'the wire () has a wire diameter d, which is'}5. The medical device as claimed in one of the preceding claims claim 1 ,characterized in that{'b': '11', 'i': 'b', '#text': 'the mantle material () of the wire has a thickness which is at least 10 μm, in particular at least 15 μm, in particular 10 μm to 20 μm.'}6. The medical device as claimed in one of the preceding claims claim 1 ,characterized in that{'b': ['11', '11'], 'i': 'a', '#text': 'the volume of the core material () takes up a ...

Подробнее
31-01-2019 дата публикации

VASCULAR PROSTHESIS WITH SIDE BRANCHES

Номер: US20190029798A1
Принадлежит: JOTEC GMBH

The present invention relates a vascular prosthesis for a blood vessel of a patient, which has the following: a hollow-cylindrical main body with a main lumen extending therein, an also a multiplicity of stent rings, which are not connected to one another, are arranged spaced apart one behind the other in the longitudinal direction of the vascular prosthesis and running around in a meandering formation. The vascular prosthesis also has four side branches, which extend distally into the main lumen from fenestrations in the prosthesis material lying between the stent rings. 1. A vascular prosthesis for a blood vessel of a patient , which has the following:{'b': 1', '2', '3, 'a hollow-cylindrical main body with a longitudinal axis (L), a proximal opening and a distal opening, and also a main lumen extending between the proximal opening and the distal opening, the main body having a proximal end portion and a distal end portion, which respectively comprise the proximal opening or the distal opening, and also a middle portion arranged between the proximal end portion and the distal end portion, the proximal end portion, the middle portion, and the distal end portion each having diameters d, d, and d, respectively,'}a plurality of stent rings, which are not connected to one another, the stent rings being arranged spaced apart one behind the other in the longitudinal direction of the vascular prosthesis and running around in a meandering formation, the stent rings respectively having ogives and webs connecting them,a prosthesis material, to which the stent rings are attached, and{'b': 2', '1', '3, "four side branches, which extend, from fenestrations in the prosthesis material lying between the stent rings, into and within the main lumen towards the distal opening, each side branch having a first side-branch opening and a second side-branch opening and also a side-branch lumen extending between the first side-branch opening and the second side-branch opening, the first ...

Подробнее
31-01-2019 дата публикации

Kink-resistant stent devices and related methods

Номер: US20190029852A1
Автор: Colin Kealey, Vikas Gupta
Принадлежит: Monarch Biosciences Inc

A device includes an elastic tubular stent including struts forming closed cells arranged in rows along a circumferential direction of the stent, with each cell having a first obtuse-angled corner on one end of the cell along a longitudinal direction of the stent and a second obtuse-angled corner on an opposing end of the cell along the longitudinal direction. The stent may be fabricated by cutting an array of quadrilateral cells in a nitinol hypotube to form a stent, with each cell having four corners with approximately equal angles. The stent may then be expanded radially such that each cell has a first obtuse-angled corner on one end of the cell along a longitudinal direction of the stent and a second obtuse-angled corner on an opposing end of the cell along the longitudinal direction, and heat treated to fix the shape of the stent.

Подробнее
31-01-2019 дата публикации

Branch Stent

Номер: US20190029853A1
Автор: GERSHLICK Anthony

This disclosure relates to a stent for use in vascular interventions, the stent comprising a first portion for placing in a first lumen and a second portion for placing in a region of a branch point at which the first lumen branches off a second lumen, the second portion comprising one or more rings linked by second links to the first portion and, if the second portion comprises two or more rings, together. The first and second portions are configured to be different to facilitate controlled longitudinal deformation of the second portion. 1. A stent for use in vascular interventions , the stent comprising a first portion for placing in a first lumen and a second portion for placing in a region of a branch point at which the first lumen branches off a second lumen ,the second portion comprising one or more rings linked by second links to the first portion and, if the second portion comprises two or more rings, together,wherein each second link comprises three straight portions joined by a bend between each pair of straight portions.2. A stent according to claim 1 , each outer of the three straight portions being joined to a ring of the second portion or to the first portion.3. A stent according to or claim 1 , each ring in the second portion being defined by a meander pattern extending between opposed bends spaced apart along the stent4. A stent according to any preceding claim claim 1 , the second portion comprising a first and a second ring claim 1 , the first ring being joined to the first portion and to the second ring and the second ring defining a free end of the second portion.5. A stent according to any preceding claim claim 1 , the first portion comprising a plurality of rings linked together by first links claim 1 , each ring being defined by a meander pattern extending between opposed bends spaced apart along the stent.6. A stent for use in vascular interventions claim 1 , the stent comprising a first portion for placing in a first lumen and a second ...

Подробнее
30-01-2020 дата публикации

MEDICAL DEVICE SUITABLE FOR LOCATION IN A BODY LUMEN

Номер: US20200030122A1
Принадлежит: Veryan Medical Limited

A stent suitable for deployment in a blood vessel to support at least part of an internal wall of the blood vessel comprises a plurality of longitudinally spaced-apart annular elements, and a plurality of connecting elements to connect adjacent annular elements. Each connecting element is circumferentially offset from the previous connecting element. Upon application of a load to the stent, the stent moves from an unloaded configuration to a loaded configuration. In the unloaded configuration the longitudinal axis of the stent is straight, and the stent is cylindrically shaped. In the loaded configuration the longitudinal axis of the stent is curved in three-dimensional space, and the stent is helically shaped. 1. A medical device suitable for location in a body lumen , wherein upon application of a load to the device the device is movable from an unloaded configuration to a loaded configuration , wherein in the unloaded configuration at least part of a longitudinal axis of the device is curved in a two-dimensional plane; wherein in the loaded configuration at least part of the longitudinal axis of the device is curved in three-dimensional space; the device being biased to achieve the three-dimensional curvature during loading.2. A device as claimed in wherein in the loaded configuration at least part of the device is substantially helically shaped.3. A device as claimed in wherein in the loaded configuration at least part of the device is substantially spiral shaped.4. A device as claimed in wherein the device is configured to move from the unloaded configuration to the loaded configuration upon application of a compressive load to the device.5. A device as claimed in wherein the device comprises a plurality of annular elements.6. A device as claimed in wherein the device comprises a plurality of primary connecting elements to connect adjacent annular elements.7. A device as claimed in wherein the device comprises a first primary connecting element to connect a ...

Подробнее
30-01-2020 дата публикации

Thin-film micromesh and related methods

Номер: US20200030126A1
Автор: Colin Kealey, Vikas Gupta
Принадлежит: Monarch Biosciences Inc

Thin-film mesh for medical devices and related methods are provided. The thin-film mesh may include slits to be expanded into pores, and the expanded thin-film mesh may be used as a cover for a stent device. The thin-film mesh has a tube-shape and the slits may be angled with respect to a longitudinal axis of the tube-shape thin-film mesh. The angled slits allow for the thin-film mesh to expand in multiple dimensions, including along the longitudinal axis and along the circumferential direction of the tube-shape thin-film mesh. The slits may be provided in diagonal rows arranged in longitudinal columns. Longitudinal columns of different types of slits may be arranged along the circumferential direction on the tube-shape thin-film mesh to form a zig-zag pattern of slits. The thin-film mesh may be formed from thin-film Nitinol (TFN) and may be fabricated via sputter deposition on a micropatterned wafer.

Подробнее
30-01-2020 дата публикации

Stent

Номер: US20200030127A1
Принадлежит: Terumo Corporation

In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer. 1. A stent delivery device comprising:a stent having proximal loops with one or more coils wrapped around the proximal loops;a pusher used to deliver the stent through a catheter;the pusher having a distal portion with first and second enlarged diameter regions, the first and second enlarged diameter regions separated by a reduced diameter region;wherein the one or more coils are contained within the reduced diameter region with clearance between the one or more coils and the first and second enlarged diameter regions while the pusher delivers the stent through the catheter.2. The stent delivery device of claim 1 , wherein the coils are radiopaque.3. The stent delivery device of claim 1 , wherein the first and second enlarged diameter regions are radiopaque marker bands.4. The stent delivery device of claim 1 , wherein the coils are distal of a proximal end of the stent.5. The stent delivery device of claim 1 , wherein proximal retraction of the pusher causes the coils to contact the first enlarged diameter region.6. The stent delivery device of claim 1 , wherein distal pushing of the pusher causes the coils to contact the second enlarged diameter region.7. The stent delivery device of claim 1 , wherein the stent has a plurality of proximal loops claim 1 , with some larger proximal loops and some smaller proximal loops.8. The stent delivery device of claim 7 , wherein only the larger proximal loops utilize the coils.9. The stent delivery device of claim 1 , wherein the stent has a plurality of distal loops claim 1 , with some larger distal loops and some smaller distal ...

Подробнее
30-01-2020 дата публикации

STENT SYSTEM DEPLOYMENT METHOD FOR BIFURCATED LESION

Номер: US20200030128A1
Автор: Al-Saadon Khalid
Принадлежит:

A deployment apparatus and method for deploying one or more stents to a bifurcated vessel is provided. The invention is particularly suited for T-type bifurcated vessels where a side branch extends from a main branch. The deployment apparatus has a primary inflatable portion for engagement within the main branch and a secondary inflatable portion for engagement within the side branch. A main stent is arranged on the primary inflatable portion and radially expanded within the main branch while the secondary inflatable portion maintains registration with the side branch. A side branch stent is then arranged on the secondary inflatable portion and expanded within the side branch while the primary inflatable portion maintains registration with the expanded main stent. A bifurcated stent system suitable for bifurcated lesions is also provided comprising a side branch stent with a shaped end designed to engage a similarly shaped side opening in a main stent. 1. A method for deployment of at least one stent in a bifurcated vessel having a main branch from which a side branch extends therefrom , comprising the steps of:providing an inflatable apparatus having a primary inflatable portion and a secondary inflatable portion;arranging a first stent on said primary inflatable portion;deploying said inflatable apparatus to said bifurcated vessel and positioning said primary inflatable portion in said main branch and said secondary inflatable portion in said side branch;inflating said primary and said secondary inflatable portions so as to cause said first stent to radially expand within said main branch while said secondary inflatable portion maintains registration with said side branch.2. The method of claim 1 , further comprising the step of positioning said secondary inflatable portion through an opening in said first stent when arranging said first stent on said primary inflatable portion.3. The method of claim 2 , further comprising the steps of:removing said inflatable ...

Подробнее
04-02-2021 дата публикации

Stent

Номер: US20210030570A1
Принадлежит: MicroVention Inc

A stent with varying porosity is described. The stent can be comprised of multiple stents attached together. A braided stent may have selected regions of increased thickness. The stent may be comprised of wires that are welded together at their ends in order to minimize vessel trauma. The stent may comprise a helically wound radiopaque wire wound through the stent.

Подробнее
09-02-2017 дата публикации

Percutaneous endovascular apparatus for repair of aneurysms and arterial blockages

Номер: US20170035547A1
Автор: Timur P. Sarac
Принадлежит: Tmt Systems

An endovascular apparatus is provided for treating the effects of vascular disease including aneurysms and arterial blockages using a percutaneous, minimally invasive technique. In one embodiment the endovascular apparatus includes a tubular sleeve having a cranial end, a first caudal branch, and a second caudal branch such that the tubular sleeve is shaped like an upside down “Y.” The apparatus further includes at least one expandable attachment device attached to the tubular sleeve for securing the endovascular apparatus to an interior wall of a vessel.

Подробнее
11-02-2016 дата публикации

Wing Bifurcation Reconstruction Device

Номер: US20160038153A1
Автор: Losordo Michael, MA Jianlu
Принадлежит:

An intraluminal device may be used at a bifurcation to anchor in an afferent vessel, allow perfusion to efferent vessels, and act as scaffolding to inhibit herniation of objects out of a neck of a bifurcation aneurysm. An intraluminal device may include a first side; a second side opposite the first side across a longitudinal axis of the intraluminal device; a proximal section configured to anchor in an afferent vessel; a distal section comprising a first wing and a second wing wherein, in an expanded state, the first wing extends from the first side to the second side and the second wing extends from the second side, through an opening of the first wing, and to the first side. 1. A method of delivering an intraluminal device comprising:positioning the intraluminal device within a body vessel while in a compressed state, the intraluminal device comprising (i) a proximal section, (ii) a distal section having (a) a first wing including first base struts connected to each other by a first end strut and (b) a second wing including second base struts connected to each other by a second end strut, and (iii) at least two junctures between the proximal section and the distal section, wherein the first wing and the second wing are fixedly connected to each other only at the at least two junctures;expanding the intraluminal device from the compressed state to an expanded state in which (i) the first base struts extend from different ones of the at least two junctures and along a first side of the distal section and the first end strut is on a second side of the distal section, substantially opposing the first side, (ii) the second wing extends through an opening in the first wing, and (iii) the second base struts extend from different ones of the at least two junctures and along the second side and the second end strut is on the first side.2. The method of claim 1 , wherein the intraluminal device is positioned within the body vessel while within a sheath claim 1 , and ...

Подробнее
11-02-2016 дата публикации

Endovascular graft having a cannulation pocket

Номер: US20160038319A1
Автор: Zoe Barrand
Принадлежит: Cook Medical Technologies LLC

A stent graft for placement in a lumen of a patient is disclosed. The stent graft comprises: a main tubular body of a biocompatible graft material having a main lumen, the main tubular body having a proximal end and a distal end; a side arm extending from the main tubular body, the side arm having a side arm lumen, the side arm lumen being in fluid communication with the main lumen through a side arm opening in the main tubular body; and a cannulation pocket. The pocket comprises: an exit aperture positioned opposite the side arm opening; an entry aperture longitudinally spaced from the entry aperture in a direction toward the distal end of the main tubular body; and a wall, the wall laterally spaced from the main lumen so as to provide a guide surface for a cannula fed through the entry aperture.

Подробнее
08-02-2018 дата публикации

Anti-migration stent with quill filaments

Номер: US20180036153A1
Принадлежит: Boston Scientific Scimed Inc

A stent that includes a plurality of quill filaments. Each quill filament includes filament material, a surface, and a plurality of quills. Each quill has a tip, a body, and a base where the body extends from the base to the tip. The quill filaments can be interwoven to form the stent or the quill filaments can be engaged to the framework of a stent.

Подробнее
08-02-2018 дата публикации

Stent

Номер: US20180036155A1
Принадлежит: MICROVENTION, INC.

In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer. 1. An implant device comprising:a first woven cylindrical layer having a first porosity; said first woven cylindrical layer being formed from a single first wire crossing back and forth between a first end and a second end of said first woven cylindrical layer at a plurality of locations to form said first generally cylindrical shape with a plurality of loops at said first end and said second end; and,a second woven cylindrical layer having a second porosity, forming a second generally tubular shape, and located within said first generally tubular shape; said second woven layer being formed from one or more wires.2. The implant device of claim 1 , wherein said single first wire comprises a plurality of reduced diameter regions.3. The implant device of claim 2 , wherein said plurality of reduced diameter regions are positioned along said first wire at overlapping wire positions.4. The implant device of claim 2 , wherein said plurality of reduced diameter regions are positioned along said single first wire at overlapping wire positions when said implant device is in an expanded configuration claim 2 , so as to decrease a thickness of said implant device.5. The implant device of claim 2 , wherein said plurality of reduced diameter regions are positioned along said first wire at overlapping wire positions when said implant device is in a compressed configuration claim 2 , so as to decrease a thickness of said implant device.6. The implant device of claim 2 , wherein said reduced diameter regions are caused by electropolishing or etching.7. The implant device of claim 2 , ...

Подробнее
24-02-2022 дата публикации

Stent and Catheter Systems for Treatment of Unstable Plaque and Cerebral Aneurysm

Номер: US20220054286A1
Автор: GOYAL Mayank
Принадлежит:

The invention generally relates to co-axial stent and catheter systems and medical procedures utilizing these systems. The co-axial stent system is characterized by two-coaxial stents, including an outer resorbable stent and an inner metal stent used to effect deployment of the resorbable stent. The stents may use for treatment of unstable plaque and/or thrombus at the carotid bifurcation and particularly those that are not causing any significant stenosis. The stents may also be used for treatment of cerebral aneurysms. The invention further describes related, equipment, uses and kits for the treatment of unstable plaque and/or thrombus and/or aneurysms. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. (canceled)13. (canceled)14. (canceled)15. (canceled)16. (canceled)17. (canceled)18. A kit for the treatment of an unstable plaque or an aneurysm at a desired location in a patient , the kit comprising:at least one guide catheter (GC) adapted for placement proximal to the desired location;at least one guide wire adapted for placement distal to the desired location;at least one microcatheter adapted for placement distal to the desired location over the guide wire;at least one resorbable stent (RS) assembly adapted for placement adjacent to the desired location and deployable through the at least one microcatheter each RS assembly having a RS adapted to stabilize the unstable plaque or aneurysm for a therapeutically effective time period and resorbable into the patient over a resorb time.19. The kit as in where the GC is at least one balloon guide catheter (BGC) for occluding blood flow.20. The kit as in further comprising at least one micro-balloon (MB) for occluding blood flow through the ECA.21. The kit as in where the kit includes at least two resorbable stent assemblies each having a resorbable stent claim 18 , and where the resorbable stents have at least one ...

Подробнее
07-02-2019 дата публикации

Atraumatic gastrointestinal anchor

Номер: US20190038445A1
Принадлежит: GI Dynamics Inc

The present invention relates to methods and articles for anchoring within a natural bodily lumen. An anchor is adapted to provide differing radially-outward forces along its length, a securing force and a transitional force. Production of these forces can be controlled by varying a physical property of the anchor, such as its stiffness, thickness, or shape. For example, the stiffness of an elongated anchor can be varied from a relatively soft value at its proximal and distal ends to a relatively stiff value at its center by varying the diameter of wire forming the anchor, thereby tailoring it to an intended application. Such force tailoring can be combined with external barbs and used to reliably anchor other instruments, such as feeding tubes and intestinal sleeves.

Подробнее
06-02-2020 дата публикации

Artificial vascular graft and method for making same

Номер: US20200038168A1
Автор: Yasuharu Noishiki
Принадлежит: Nicem Ltd

A suture to be used in producing a medical instrument provided with a sutured site such as a stent graft, an artificial blood vessel or an artificial heart valve, has two components, i.e., a high melting-point component and a low-melting point component, the difference between the melting points of components being 30° C. or more and the low-melting point component is exposed on the suture surface entirely along the length direction. When a medical material formed of a fabric or a film is sutured or knotted with the suture and then the suture site is heated at such a temperature not allowing the high-melting point component but the low-melting point component alone to melt, the sutured site is fused and fixed. Thus, a knot or a seam, which sustains the fiber shape and strength and never becomes loose, can be formed.

Подробнее
18-02-2016 дата публикации

ENDOLUMINAL DRUG DELIVERY DEVICE

Номер: US20160045341A1
Принадлежит: Cook Medical Technologies LLC

A drug delivery device () includes expandable element () formed of a braided structure having a body portion () and first and second end cones (). The end cones are attached at their necks () to a catheter assembly (). The expandable element () can expand to a vessel contacting configuration, in which the body portion () contacts the vessel wall. Bioactive agent () covers at least the outer surface of the body portion () such that bioactive material can be administered to a vessel wall. The end cones () have an open structure allowing unrestricted passage of blood through the device () in the deployed configuration, such that blood flow can be maintained during the administration of bioactive agent () from the device (). The expandable element () can be radially contracted by extending it in the longitudinal direction, both for deployment endoluminally to the treatment site and also for retrieval following the administration of the bioactive material. 1. A vascular delivery device for delivering a bioactive agent to a vessel wall , including:an expandable frame element having a body portion formed of at least one braided or knitted wire and first and second end portions formed of at least one braided or knitted wire, the body portion being radially expandable from a contracted to a deployed configuration, and having an open interior and an outer surface;the first and second end portions having an open structure allowing passage to the open interior of the body portion;a carrier element on which the expandable frame is disposed, wherein the first and second end portions are connected to the carrier element;and a bioactive material disposed at least on the outer surface of the body portion;wherein the body portion has, in the expanded condition, a knit or braid weave which is tighter than the knit or braid weave of the first and second end portions.2. A vascular delivery device according to claim 1 , wherein the body portion is generally hollow.3. A vascular delivery ...

Подробнее
16-02-2017 дата публикации

Deformable lumen support devices and methods of use

Номер: US20170042706A1
Принадлежит: CeloNova Stent Inc

Lumen support devices and methods of their use are provided. A lumen support includes one or more plastically deformable cells having two stable configurations with no stable configurations between the two stable configurations. The lumen support device may be plastically deformed to other stable configurations.

Подробнее
15-02-2018 дата публикации

Prosthesis having pivoting fenestration

Номер: US20180042713A1
Принадлежит: Cook Medical Technologies LLC

The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, and a second perimeter attached to and surrounding the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape. In one aspect, the prosthesis includes at least three pivotable fenestrations,

Подробнее
16-02-2017 дата публикации

Intravascular stent

Номер: US20170042710A1
Автор: Diem Uyen Ta
Принадлежит: Abbott Cardiovascular Systems Inc

An expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. In one aspect, the stent includes a butterfly pattern to which connecting links are attached. In another aspect, the stent embodies a non-directional structure.

Подробнее
15-02-2018 дата публикации

MULTI-ELEMENT BIORESORBABLE INTRAVASCULAR STENT

Номер: US20180042740A1
Принадлежит: EFEMORAL MEDICAL LLC

A multi-element, bioresorbable, vascular stent may be used to maintain or enhance patency of a blood vessel. The stent may be used in peripheral blood vessels, which may be long and/or tortuous. By using multiple, separate stent elements that are balloon expandable, the multi-element stent may be stronger than a traditional self-expanding stent but may also be more flexible, due to its multiple-element configuration, than a traditional balloon-expandable stent. Thus, the multi-element, bioresorbable, vascular stent described herein may be particularly advantageous for treating long lesions in tortuous peripheral blood vessels. 1. A device for placement within a blood vessel to maintain or enhance blood flow through the blood vessel , the device comprising multiple , balloon-expandable , bioresorbable , vascular stent elements configured to be implanted in the blood vessel as a multi-element stent , with the multiple stent elements not touching one another;wherein the stent elements comprise a first set of closed cells and a second set of closed cells, wherein the first set of closed cells have a different shape or size than the second set of closed cells;wherein the first set of closed cells have a repeating longitudinally aligned pattern and a repeating circumferentially aligned pattern, wherein the second set of closed cells have a repeating longitudinally aligned pattern and a repeating circumferentially aligned pattern, wherein the first set of closed cells and the second set of closed cells are circumferentially offset, and wherein the first set of closed cells and the second set of closed cells have a helically aligned alternating pattern.2. The device of claim 1 , wherein the first set of closed cells are larger cells having a first opening dimension and the second set of closed cells are smaller cells having a second opening dimension smaller than the first opening dimension;wherein each of the larger closed cells is formed by at least one wider strut and at ...

Подробнее
15-02-2018 дата публикации

DELIVERY OF MEDICAL DEVICES

Номер: US20180042745A1
Принадлежит:

A stent delivery system can include a core member, an introducer sheath, and a microcatheter. The core member can have a first section and a second section distal to the first section. The second section can have a bending stiffness per unit length that is less than a bending stiffness per unit length of the first section. The introducer sheath can have a lumen configured to receive the core member therethrough. The introducer sheath can have a length of at least about 80 cm. The microcatheter can have a lumen and a proximal end configured to interface with a distal end of the introducer sheath for delivering the core member into the microcatheter lumen. 1an elongate core member sized for insertion into a blood vessel, the core member configured for advancing a stent toward a treatment location in the blood vessel, the core member comprising a longitudinally extending tube having a helical cut extending along the tube, the helical cut having an axial length of at least 50 cm and being continuous along the axial length.. A stent delivery system, comprising: This application is a continuation of U.S. patent application Ser. No. 14/040,477, filed Sep. 27, 2013, which claims the benefit of U.S. Provisional Patent Application No. 61/870,755, filed Aug. 27, 2013. The entirety of each of these applications is incorporated herein by reference.Walls of the vasculature, particularly arterial walls, may develop areas of pathological dilatation called aneurysms. As is well known, aneurysms have thin, weak walls that are prone to rupturing. Aneurysms can be the result of the vessel wall being weakened by disease, injury, or a congenital abnormality. Aneurysms could be found in different parts of the body, and the most common are abdominal aortic aneurysms and brain or cerebral aneurysms in the neurovasculature. When the weakened wall of an aneurysm ruptures, it can result in death, especially if it is a cerebral aneurysm that ruptures.Aneurysms are generally treated by excluding ...

Подробнее
14-02-2019 дата публикации

THIN FILM MESH HYBRID FOR TREATING VASCULAR DEFECTS

Номер: US20190046343A1
Автор: Choubey Animesh
Принадлежит:

Devices that can be delivered into a vascular system to divert flow are disclosed herein. According to some embodiments, devices are provided for treating aneurysms b diverting flow. An expandable device can comprise, for example, a plurality of strut regions and a plurality of bridge regions. Each of the strut regions may extend circumferentially about the expandable device and include a plurality of struts. Each of the plurality of bridge regions may be attached to and extend between two of the strut regions and comprise a plurality first bridges and second bridges that intersect one another and are movable relative to one another at their intersections. 1. An expandable device comprising:a plurality of strut regions extending circumferentially about the expandable device and including a plurality of struts; anda plurality of bridge regions extending between adjacent strut regions and including a plurality of bridges, the plurality of bridges including first bridges and second bridges, wherein each of the first bridges intersects one or more of the second bridges within each of the bridge regions, and wherein the first bridge is configured to move relative to the second bridge at each of the intersections.2. The expandable device of claim 1 , wherein the first bridges extend in a first rotational direction and the second bridges extend in a second rotational direction different than the first rotational direction.3. The expandable device of claim 1 , wherein each of the struts is coupled to another strut at an apex claim 1 , and wherein at least some of the apices connect to one of (a) one of the first bridges or (b) one of the second bridges.4. The expandable device of claim 1 , wherein each of the struts is coupled to another strut at an apex claim 1 , and wherein at least one of the apices connects to one of the first bridges and to one of the second bridges.5. The expandable device of claim 1 , wherein the struts may be connected end-to-end within the strut ...

Подробнее
25-02-2016 дата публикации

Partial Circumferential Stent With Non-Radial Apposition

Номер: US20160051803A1
Принадлежит:

A medical device for sealing and repairing defects in a body lumen wall includes a wire frame and a partially-circumferential stent body. In some embodiments, the endolumenal sealing devices provided herein are well-suited for use in the GI tract including the colon. That is the case because the partially-circumferential sealing devices are configured to be compliant with the peristaltic movements of the GI tract. This feature can enable the sealing devices to resiliently remain located in a desired position within the GI tract, such that the defect in the lumen wall is sealed by the presence of the sealing device. 160-. (canceled)61. An implantable medical device for treating a portion of a body lumen wall , the device comprising:a membrane frame;a membrane material disposed on at least a portion of the membrane frame;a first strut extending from the membrane frame; anda second strut extending from the membrane frame,wherein the first and second struts are configured to press at least a portion of the membrane material into contact with the wall of the body lumen, andwherein the first and second struts each comprise an elongate member that is shaped as two arcuate segments and at least one wavy segment when the device is in a fully expanded configuration.62. The device of claim 61 , wherein the portion of the body lumen wall comprises a defect and the membrane material is configured to overlay the defect.63. The device of claim 61 , wherein the first and second struts each comprise elongate members that are unitary with an elongate member of the membrane frame.64. The device of claim 61 , wherein the first and second struts each comprise elongate members that are joined to an elongate member of the membrane frame.65. The device of claim 61 , wherein the first and second struts each comprise elongate members that are joined to an elongate member of the membrane frame by one or more of a weld claim 61 , an adhesive claim 61 , and a sleeve.66. The device of claim 61 , ...

Подробнее
25-02-2016 дата публикации

Partial Circumferential Stent With Non-Radial Apposition

Номер: US20160051804A1
Принадлежит:

A medical device for sealing and repairing defects in a body lumen wall includes a wire frame and a partially-circumferential stent body. In some embodiments, the endolumenal sealing devices provided herein are well-suited for use in the GI tract including the colon. That is the case because the partially-circumferential sealing devices are configured to be compliant with the peristaltic movements of the GI tract. This feature can enable the sealing devices to resiliently remain located in a desired position within the GI tract, such that the defect in the lumen wall is sealed by the presence of the sealing device. 1. An implantable medical device for treating a portion of a body lumen wall , the device comprising:a membrane frame;a membrane material disposed on at least a portion of the membrane frame said membrane material having a first surface and a second surface;a pad positioned on said first surface of said membrane material;a first strut extending from the membrane frame; anda second strut extending from the membrane frame, wherein the first and second struts are configured to exert opposing non-orthogonal forces to the membrane frame to thereby press at least a portion of said first surface of the membrane material into contact with the body lumen wall.2. The device of claim 1 , wherein the portion of the body lumen wall comprises a defect and the membrane material is configured to overlay the defect.3. The device of claim 1 , wherein the first and second struts each comprise elongate members that are unitary with an elongate member of the membrane frame.4. The device of claim 1 , wherein the first and second struts each comprise elongate members that are joined to an elongate member of the membrane frame.5. The device of claim 1 , wherein the first and second struts each comprise elongate members that are joined to an elongate member of the membrane frame by one or more of a weld claim 1 , an adhesive claim 1 , and a sleeve.6. The device of claim 1 , ...

Подробнее
25-02-2016 дата публикации

Treatment for cardiac conductance abnormalities

Номер: US20160051822A1
Автор: Allon R. GUEZ
Принадлежит: DREXEL UNIVERSITY, John R. Bullinga

Methods and apparatuses are provided for treating cardiac conductive disorders that include implantation of a network of material that adaptively corrects the electrical conductivity of heart tissues and restores “normal” conductance. The methods and apparatuses disclosed herein involve the delivery of a material to a subject's heart in order to restore normal conductance in a minimally invasive, tunable, localized, and reversible manner, without artificial electrical stimulation.

Подробнее
13-02-2020 дата публикации

ANCHORING OF A PROSTHETIC VALVE

Номер: US20200046496A1
Принадлежит:

A prosthetic valve includes a tubular valve body, snares, and an upstream support. A native valve of a heart of a subject is disposed between an atrium and a ventricle of the heart, and has an annulus and leaflets. The prosthetic valve is advanced to the heart while in a compressed state. The prosthetic valve is positioned within the heart such that the snares are disposed upstream of the annulus and leaflets. The snares are expanded radially outwardly upstream of the leaflets. Subsequently, the prosthetic valve is moved in a downstream direction such that the snares become disposed downstream of the leaflets. While the snares remain downstream of the leaflets, the upstream support is expanded within the atrium, and the upstream support is placed against an upstream surface of the annulus. Other embodiments are also described. 1. A method for use with a native valve of a heart of a subject , the native valve being disposed between an atrium and a ventricle of the heart , and having an annulus and leaflets , the method comprising:advancing a prosthetic valve to the heart while the prosthetic valve is in a compressed state thereof, the prosthetic valve including a tubular valve body, snares, and an upstream support;positioning the prosthetic valve within the heart such that the snares are disposed upstream of the annulus and leaflets, and expanding the snares radially outwardly upstream of the leaflets;subsequently, moving the prosthetic valve in a downstream direction such that the snares become disposed downstream of the leaflets; andwhile the snares remain downstream of the leaflets, expanding the upstream support within the atrium and placing the upstream support against an upstream surface of the annulus.2. The method according to claim 1 , wherein expanding the snares comprises expanding the snares while a downstream portion of the tubular valve body remains compressed.3. The method according to claim 2 , wherein moving the prosthetic valve in the downstream ...

Подробнее
22-02-2018 дата публикации

STENT HAVING FLEXIBLY CONNECTED ADJACENT STENT ELEMENTS

Номер: US20180049898A1
Принадлежит:

An open stent (a stent having open space through its thickness at locations between the ends of the stent), incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect adjacent, spaced-apart stent elements. Preferably the spaced-apart adjacent stent elements are the result of forming the stent from a helically wound serpentine wire having space provided between adjacent windings. Other stent forms such as multiple, individual spaced-apart ring-shaped or interconnected stent elements may also be used. The connecting elements are preferably longitudinally oriented. 1. A cover for use with an implantable stent , said cover comprising an integral , non-woven sheet having a length and width and an area defined as a the length multiplied by the width , said cover having a multiplicity of perforations therethrough , wherein said perforations collectively cover an area that is at least 50% of the sheet area , wherein said perforations have a minimum aperture size of about 0.10 mm.2. A cover according to wherein said perforations have a generally hexagonal shape.3. A diametrically expandable endoprosthesis comprising a substantially open tubular stent and at least one flexible non-metallic strip claim 1 , said strip oriented substantially longitudinally and connected to the stent to limit foreshortening and elongation of the stent.4. A diametrically expandable stent comprising at least two circumferentially oriented spaced-apart stent elements and at least one substantially longitudinally oriented flexible connecting strip connecting adjacent spaced apart stent elements claim 1 , said stent having a length between ends of the stent and a deployed circumference claim 1 , wherein said stent has a tubular area comprising the stent length multiplied by the deployed circumference and wherein at least 50% of the tubular area is open.5. A diametrically expandable stent according to wherein at least 60% of the tubular area is open. ...

Подробнее
03-03-2016 дата публикации

INTRAVASCULAR ANEURYSM TREATMENT DEVICE AND METHODS

Номер: US20160058589A1
Автор: BAR Eli, HOLZER Asher, Paz Ofir
Принадлежит: INSPIREMD, LTD.

An intravascular device configured to treat an aneurysm that includes a support structure including metal struts configured to be positioned in a body lumen and defining a central fluid passage that extends axially along the support structure, and a knitted mesh cover disposed over an exterior thereof and across a radial arc and along a length of the support structure sufficient to exceed an opening of an aneurysm to be treated, and the cover includes a polymer fiber having a diameter of at least 40 nanometers to 30 microns and apertures therethrough, the apertures being sized to prevent blood from passing through the device to prevent further expansion of the aneurysm. Devices including apertures that are at least 20 microns and sized to minimize or prevent an aneurysm-filling material from exiting the aneurysm through the knitted mesh cover and support structure, and methods of stenting, are also encompassed. 1. An intravascular device configured to treat an aneurysm , which comprises:a support structure comprising metal struts configured to be positioned in a body lumen and defining a central fluid passage that extends axially along the support structure; anda knitted mesh cover disposed over an exterior of the support structure, wherein the cover extends across a radial arc and along a length of the support structure sufficient to exceed an opening of an aneurysm to be treated and the cover comprises a polymer fiber having a diameter of at least 40 nanometers to 30 microns arranged to provide apertures through the cover which apertures are at least 20 microns and are sized to minimize or prevent an aneurysm-filling material from exiting the aneurysm through the knitted mesh cover and support structure into the central fluid passage.2. The intravascular device of claim 1 , wherein the aneurysm-filling material comprises one or more coils.3. The intravascular device of claim 1 , wherein a porous structure is disposed over the aneurysm-filling material to increase ...

Подробнее
03-03-2016 дата публикации

MEDICAL TUBULAR BODY

Номер: US20160058590A1
Автор: Mukai Yuki
Принадлежит: KANEKA CORPORATION

An object of the present invention is to provide a medical tubular body that is excellent in visibility under X-ray fluoroscopic control, insertion property into a catheter and sliding property in a catheter, that suppresses contact of a marker with a tubular body or an adjacent marker in a diameter reduction state, and that is able to further reduce its diameter. The present invention provides a medical tubular body comprising a tubular body whose diameter is expandable and a marker provided inside the tubular body. 1. A medical tubular body comprising a tubular body whose diameter is expandable and a marker provided inside the tubular body.2. The medical tubular body according to claim 1 , wherein the marker is fixed to an inner surface of the tubular body.3. The medical tubular body according to claim 1 , wherein the marker is provided at a non-deformation part which constitutes a part of the tubular body.4. The medical tubular body according to claim 1 , wherein the marker is provided at a plane part of the inner surface of the tubular body.5. The medical tubular body according to claim 1 , wherein the marker is welded to the inner surface of the tubular body.6. The medical tubular body according to claim 1 , wherein the marker has a size so as to be placed in an inner space of the tubular body in a state where the tubular body is reduced in diameter.7. The medical tubular body according to claim 1 , comprising at least two of the markers claim 1 ,wherein the markers have a size so as not to contact with each other in the state where the tubular body is reduced in diameter.8. The medical tubular body according to claim 7 , wherein the two of the markers are provided at different positions in an axial direction of the tubular body.9. The medical tubular body according to claim 8 , further comprising a plurality of support rods whose lengths are different from each other claim 8 ,wherein the marker is provided at an end part of each of the support rod.10. The ...

Подробнее
21-02-2019 дата публикации

FLOW ATTENUATION DEVICE

Номер: US20190053811A1
Принадлежит:

An embolic device for treating aneurysms or other vascular disorders may be more compliant than conventional devices, while still achieving desired porosity. In particular, the device may achieve the desired porosity only at discrete sections along the length of the device where such a porosity is required (e.g., sections that will block the neck of the aneurysm upon deployment). The remaining sections of the device can be configured to increase the device's compliance. For example, the remaining sections can be formed from less material than the sections with the desired porosity. In some instances, the sections with the desired porosity are formed from mesh-screen segments and the remaining sections are formed from coil segments. In some instances, the mesh-screen segments are configured to further enhance the device's compliance. For example, the mesh-screen segment can be formed from a layered structure that achieves greater compliance than conventional braided structures. 1. An embolic device for use in treating a vascular disorder , the embolic device comprising:a first coil segment;a second coil segment; anda mesh-screen segment,wherein the mesh-screen segment is disposed between the first coil segment and the second coil segment along a length of the embolic device.2. The embolic device of claim 1 , wherein the first and second coil segments each comprise a helically wound wire.3. The embolic device of claim 1 , wherein the first and second coil segments each comprise a greater compliance than the mesh-screen segment.4. The embolic device of claim 1 , wherein the mesh-screen segment comprises a greater porosity than each of the first and second coil segments.5. The embolic device of claim 4 , wherein claim 4 , when the mesh-screen segment is in a deployed configuration claim 4 , the mesh-screen segment is 60% to 80% porous.6. The embolic device of claim 1 , wherein the mesh-screen segment comprises two layers.7. The embolic device of claim 6 , wherein the ...

Подробнее
21-02-2019 дата публикации

Non-migrating stent devices and methods

Номер: US20190053922A1
Принадлежит: Wake Forest University Health Sciences

Non-migrating stent devices and methods for using the devices are provided for treatment of visceral anastomosis strictures or vascular ostium high grade stenosis. For example, placement of a non-migrating stent may be appropriate following a surgical procedure such as hollow visceral anastomosis.

Подробнее
03-03-2016 дата публикации

Devices and methods for control of blood pressure

Номер: US20160058989A1
Принадлежит: Vascular Dynamics Inc

Apparatus and methods are described including an implantable device shaped to define (a) at least two artery-contact regions, the artery-contact regions comprising struts that are configured to stretch an arterial wall by applying pressure to the arterial wall, and (b) at least two crimping regions that comprise locking mechanisms configured to prevent the crimping regions from becoming crimped due to pressure from the wall of the artery on the artery-contact regions. The crimping regions are configured to be crimped during insertion of the device, via a catheter, by the locking mechanisms being unlocked during insertion of the device. Other embodiments are also described.

Подробнее
04-03-2021 дата публикации

Methods, Devices, And Compositions For Treating Vascular Aneurysms

Номер: US20210059843A1
Принадлежит:

Methods, compositions, and devices for treating a vascular aneurysm, including an abdominal aortic aneurysm, are disclosed. In particular, the various embodiments relate to a method of treating an abdominal aortic aneurysm by increasing the mechanical stiffness of an aortic segment adjacent to the abdominal aortic aneurysm in a subject. The mechanical stiffness of the adjacent aortic segment may be increased, for example, by applying a surgical adhesive or intravascular stent. Such treatment reduces stress on the aortic wall and limits further growth of the abdominal aortic aneurysm. 1. (canceled)2. A method of treating a subject for a vascular aneurysm in an artery , the method comprising increasing a mechanical stiffness of at least one vascular segment adjacent to the vascular aneurysm in the subject.3. The method of claim 2 , wherein the increasing the mechanical stiffness comprises applying a surgical adhesive locally to the at least one vascular segment.4. The method of claim 2 , wherein the increasing the mechanical stiffness comprises implanting an intravascular stent that stiffens the at least one vascular segment.5. The method of claim 2 , wherein growth of the vascular aneurysm is reduced compared to in the absence of treating the subject.6. The method of claim 2 , wherein the subject shows decreased inflammation in the artery compared to in the absence of treating the subject.7. The method of claim 2 , wherein the subject shows decreased apoptosis in the artery compared to in the absence of treating the subject.8. The method of claim 2 , wherein the subject shows decreased production of reactive oxygen species in the artery compared to in the absence of treating the subject.9. The method of claim 2 , wherein the subject has an early stage vascular aneurysm.10. The method of claim 2 , wherein the at least one vascular segment comprises a vascular segment upstream of the vascular aneurysm or a vascular segment downstream of the vascular aneurysm.11. The ...

Подробнее