ОПТИЧЕСКАЯ СИСТЕМА ДЛЯ ОФТАЛЬМОЛОГИЧЕСКОГО ХИРУРГИЧЕСКОГО ЛАЗЕРА

Изобретение относится к медицинской технике. Лазерная система для офтальмологической хирургии включает источник лазерного излучения для генерирования импульсного лазерного луча; XY-сканер для приема импульсного лазерного луча и для испускания сканирующего по направлениям XY луча, просканированного в двух направлениях, поперечных направлению Z; Z-сканер в корпусе сканера для приема луча, сканирующего по направлениям XY, и для испускания сканирующего по направлениям XYZ луча, сканировавшего дополнительно по направлению Z, зеркало для отклонения сканирующего по направлениям XYZ луча, принятого от Z-сканера; и объектив в корпусе объектива для приема отклоненного сканирующего по направлениям XYZ луча и для фокусировки принятого сканирующего по направлениям XYZ луча на целевую область, где корпус сканера отделен от корпуса объектива. Изобретение позволяет выполнять хирургические вмешательства на хрусталике глаза. 5 з.п. ф-лы, 12 табл., 19 ил.

СПОСОБ И УСТРОЙСТВО ДЛЯ НЕРАЗРУШАЮЩЕЙ ИЛИ МИНИМАЛЬНО РАЗРУШАЮЩЕЙ СВЕТОВОЙ ОБРАБОТКИ ГЛАЗА

Группа изобретений относится к медицине и медицинской технике, а именно к способам и системам для неразрушающей или минимально разрушающей световой обработки хрусталика глаза животного или человека. Система содержит лазерную систему для излучения по меньшей мере одного воздействующего лазерного луча в диапазоне длин волн 700-1000 нм или 1000-1500 нм; средства фокусировки луча на выбранном участке хрусталика; средства обеспечения импульсного режима лазерного луча; средства измерения одного или нескольких типов излучения от выбранного участка; средства обработки результатов измерений одного или нескольких типов излучения; а также средства регулировки для регулировки по меньшей мере одного из параметров лазерного луча. Параметрами луча являются его фокусировка, интенсивность, длина волны, ширина импульса, частота повторений и длительность последовательности импульсов лазерного луча. Регулировка осуществляется на основании выходного сигнала средств обработки результатов измерений. Данная система ...

ИЗМЕРИТЕЛЬНЫЙ МОДУЛЬ, СОДЕРЖАЩИЙ ИНТЕРФЕЙС ДЛЯ СОЕДИНЕНИЯ С ЛАЗЕРНЫМ ПРИБОРОМ

Изобретение относится к медицине. Устройство для лазерной терапии глаз содержит лазерный прибор и первый и второй вспомогательные модули. Лазерный прибор выполнен с возможностью обеспечения сфокусированного лазерного излучения и имеет соединительный порт. Первый вспомогательный модуль может формировать интерфейс пациента и имеет контактную поверхность для глаза. Второй вспомогательный модуль содержит измерительный прибор, который выполняет измерения лазерного излучения. В некоторых вариантах осуществления измерения включают измерение длительности импульса лазерного излучения с использованием детектора, работающего на основе двухфотонного поглощения. Первый и второй вспомогательные модули выполнены с возможностью разъемного соединения с лазерным прибором через соединительный порт. Только один вспомогательный модуль может быть соединен с соединительным портом в каждый момент времени. Таким образом, первый вспомогательный модуль должен быть удален из соединительного порта до того, как второй ...

УСТРОЙСТВО ДЛЯ ОФТАЛЬМОХИРУРГИЧЕСКИХ ОПЕРАЦИЙ

Изобретение относится к области медицины, а именно к офтальмологии, и может быть использовано при хирургическом лечении катаракты. Устройство для офтальмохирургических операций содержит источник лазерного излучения, лазерный наконечник и устройство ирригации-аспирации с наконечником. Дополнительно оно снабжено устройством для концентрации лазерно-индуцированной акустической волны на естественный хрусталик глаза и устройством преобразования лазерного излучения в энергию акустической волны. Одновременное воздействие указанных устройств на естественный хрусталик глаза обеспечивает эффективное и атравматическое удаление твердых хрусталиковых масс. Техническим результатом изобретения является достижение полного разрушения и аспирации фрагментов твердых хрусталиковых масс с минимальным риском развития изменений в окружающих хрусталик тканях глаза. 18 з.п. ф-лы, 17 ил.

УСТРОЙСТВО И СПОСОБ ДЛЯ РАБОТЫ ПОСЛЕДОВАТЕЛЬНОГО ДАТЧИКА ВОЛНОВОГО ФРОНТА БОЛЬШОГО ДИОПТРИЙНОГО ДИАПАЗОНА РЕАЛЬНОГО ВРЕМЕНИ

... 1. Датчик волнового фронта, содержащий:источник 172 света, сконфигурированный, чтобы подсвечивать глаз субъекта;детектор 122;первый элемент 112 отклонения пучка, сконфигурированный, чтобы перехватывать пучок волнового фронта, возвращенный от глаза субъекта, когда глаз субъекта подсвечивается источником света, и сконфигурированный, чтобы направлять часть волнового фронта от глаза субъекта через апертуру к детектору; иконтроллер, связанный с источником света и элементом отклонения пучка, сконфигурированный для управления элементом отклонения пучка, чтобы отклонять и проецировать различные участки части кольцевой окружности волнового фронта от глаза субъекта через апертуру, и дополнительно сконфигурированный для импульсной модуляции источника света с частотой запуска, чтобы дискретизировать выбранные части кольцевой окружности на детекторе.2. Датчик волнового фронта по п. 1, причем контроллер дополнительно сконфигурирован для увеличения частоты запуска, чтобы увеличивать плотность дискретизации ...

ПРОЦЕССОР ИЗОБРАЖЕНИЙ ДЛЯ ВНУТРИХИРУРГИЧЕСКОГО ИЗОБРАЖЕНИЯ ОПТИЧЕСКОЙ КОГЕРЕНТНОЙ ТОМОГРАФИИ ЛАЗЕРНОЙ ОПЕРАЦИИ ПО УДАЛЕНИЮ КАТАРАКТЫ

... 1. Хирургическая система для удаления катаракты, содержащая лазерный источник, выполненный с возможностью создания первой группы лазерных импульсов; направляющую оптику, присоединенную к лазерному источнику, выполненную с возможностью направлять первую группу лазерных импульсов в целевую область катаракты глаза; лазерный контроллер, выполненный с возможностью создавать электронное изображение целевого шаблона сканирования, и управлять направляющей оптикой для сканирования первой группой лазерных импульсов в соответствии с частью шаблона сканирования для создания первой фоторазрушаемой области в целевой области катаракты; систему изображения Спектральной Области Оптической Когерентной Томографии (СО-ОКТ), выполненную с возможностью создания изображения, содержащего части первой фоторазрушаемой области; и процессор изображения ОКТ, выполненный с возможностью выполнения анализа изображения, при том, что лазерный контроллер выполнен с возможностью создания электронного изображения измененного ...

ОПТИЧЕСКИЙ СКАНЕР АППАРАТА ДЛЯ РАЗРЕЗАНИЯ ТКАНИ ЧЕЛОВЕКА ИЛИ ЖИВОТНОГО

ИЗМЕРИТЕЛЬНЫЙ МОДУЛЬ, СОДЕРЖАЩИЙ ИНТЕРФЕЙС ДЛЯ СОЕДИНЕНИЯ С ЛАЗЕРНЫМ ПРИБОРОМ

ЛАЗЕРНАЯ СИСТЕМА ДЛЯ ПРОВЕДЕНИЯ ОФТАЛЬМОЛОГИЧЕСКИХ ВМЕШАТЕЛЬСТВ

ОПТИЧЕСКАЯ СИСТЕМА ДЛЯ ОФТАЛЬМОЛОГИЧЕСКОГО ХИРУРГИЧЕСКОГО ЛАЗЕРА

... 1. Лазерная система для офтальмологической хирургии, содержащая: источник лазерного излучения для получения импульсного лазерного луча; XY-сканер для сканирования импульсным лазерным лучом по направлениям XY, поперечным оси Z; Z-сканер для сканирования сканированным по направлениям XY лазерным лучом по оптической оси Z; и объектив для фокусировки сканирующего по направлениям XYZ лазерного луча в целевую область, где сфокусированный сканированный лазерный луч имеет числовую апертуруи число Штреляв радиальных координатах (z, r), в миллиметрах, под любым угломазимута в целевой области; вблизи к (z, r) = (0,3; 0,0),составляет от 0,25 до 0,40 исоставляет от 0,8 до 1,0; иивходят в пределы, по меньшей мере, одной из следующих соответствующих целевых областей: вблизи (z, r) = (0,3; 6,2),составляет от 0,25 до 0,40 исоставляет от 0,8 до 1,0; вблизи (z, r) = (8,0; 0,0),составляет от 0,15 до 0,35 исоставляет от 0,8 до 1,0; и вблизи (z, r) = (7,4; 4,0),составляет от 0,15 до 0,35 исоставляет от 0,8 до ...

ОПТИЧЕСКАЯ СИСТЕМА ДЛЯ ОФТАЛЬМОЛОГИЧЕСКОГО ХИРУРГИЧЕСКОГО ЛАЗЕРА

... 1. Лазерная система для офтальмологической хирургии, содержащая: источник лазерного излучения для генерирования импульсного лазерного луча; XY-сканер для приема импульсного лазерного луча и для испускания сканирующего по направлениям XY луча, просканированного в двух направлениях, поперечных направлению Z; Z-сканер в корпусе сканера для приема луча, сканирующего по направлениям XY, и для испускания сканирующего по направлениям XYZ луча, сканировавшего дополнительно по направлению Z, зеркало для отклонения сканирующего по направлениям XYZ луча, принятого от Z-сканера; и объектив в корпусе объектива для приема отклоненного сканирующего по направлениям XYZ луча; и для фокусировки принятого сканирующего по направлениям XYZ луча на целевую область, где корпус сканера отделен от корпуса объектива.2. Лазерная система по п.1, в которой корпус сканера отделен от корпуса объектива, по меньшей мере, механически и функционально.3. Лазерная система по п.1, в которой Z-сканер включает: первый блок расширителя ...

ОПТИЧЕСКАЯ СИСТЕМА ДЛЯ ОФТАЛЬМОЛОГИЧЕСКОГО ХИРУРГИЧЕСКОГО ЛАЗЕРА

... 1. Лазерная система для офтальмологической хирургии содержит: источник лазерного излучения для получения хирургического импульсного лазерного луча, XY-сканер для сканирования по направлениям XY хирургическим импульсным лазерным лучом в поперечных направлениях, Z-сканер для сканирования по направлению Z, сканировавшим по направлениям XY хирургическим импульсным лазерным лучом, по оптической оси, один или более вспомогательных оптических блоков, генерирующих вспомогательный свет, и объектив для обеспечения общего оптического канала для сканирующего по направлениям XYZ хирургического лазерного луча и вспомогательного света через группу линз объектива в хирургическую целевую область, где линзы группы линз объектива не перемещаются относительно друг друга, и объектив не выполняет функцию динамического сканирования по направлению Z.2. Лазерная система по п.1, в которой объектив сконфигурирован для регулирования, по меньшей мере, одного из сферической аберрации, комы и аберраций высшего порядка ...

УСТРОЙСТВО СОПРЯЖЕНИЯ МЕЖДУ ЛАЗЕРНЫМ ИСТОЧНИКОМ И ОПЕРИРУЕМОЙ ТКАНЬЮ

ОПТИЧЕСКАЯ СИСТЕМА ДЛЯ ОФТАЛЬМОЛОГИЧЕСКОГО ХИРУРГИЧЕСКОГО ЛАЗЕРА

... 1. Офтальмологическая лазерная система, содержащая источник лазерного излучения для генерирования импульсного лазерного луча; XY-сканер для приема импульсного лазерного луча и для испускания сканирующего по направлениям XY луча, производящего сканирование по двум направлениям, по существу поперечным оптической оси; и многофункциональный Z-сканер для приема сканирующего по направлениям XY луча; и для испускания сканирующего по направлениям XYZ луча, причем Z-сканер имеет числовую апертуру NA и фокальное пятно в целевой области; и предназначен для модификации числовой апертуры NA, по существу независимо от сканирования фокальной глубины Z фокального пятна по оптической оси.2. Офтальмологическая лазерная система по п.1, в которой Z-сканер включает первый блок расширителя луча, подвижный блок расширителя луча и вторичный оптический регулятор.3. Офтальмологическая лазерная система по п.1, в которой испускаемый сканирующий по направлениям XYZ луч имеет геометрическую аберрацию, дифракционную ...

УСТРОЙСТВО И СПОСОБ ДЛЯ РАБОТЫ ПОСЛЕДОВАТЕЛЬНОГО ДАТЧИКА ВОЛНОВОГО ФРОНТА БОЛЬШОГО ДИОПТРИЙНОГО ДИАПАЗОНА РЕАЛЬНОГО ВРЕМЕНИ

... 1. Устройство, содержащее:позиционно-чувствительный детектор 122, сконфигурированный для вывода последовательности позиционно-чувствительных сигналов, при этом каждый позиционно-чувствительный сигнал указывает отклонение центроида выборки волнового фронта от опорной точки на детекторе, причем выборкой волнового фронта является выборка части волнового фронта в форме кольцевой окружности падающего волнового фронта, возвращенного от глаза субъекта, исистему 710, 750 обработки, связанную с позиционно-чувствительным детектором, чтобы принимать последовательность позиционно-чувствительных сигналов, причем система обработки сконфигурирована, чтобы вычислять последовательность координат отклонения, указывающих отклонение каждого центроида, вычислять центральную точку последовательности координат отклонения центроида, ассоциировать последовательность координат отклонения с эллипсом, центрированным в центральной точке, причем последовательность координат отклонения центроида подогнана к эллипсу, ...

Laservorrichtung zur Bearbeitung eines Gewebes im Vorderabschnitt eines Auges

Die Erfindung betrifft eine Lasereinrichtung 100, 900, 1000, 1300 zur Bearbeitung eines Gewebes im Vorderabschnitt eines Auges 109, mit einem Laser 101 zur Erzeugung eines Lichtstrahlbündels 102, einer optischen Vorrichtung zur Formung einer Lichtverteilung 105, 505, 705, 905, 1005, 1105, 1205 und einem abbildenden optischen System 106, 906, 1006 zur Abbildung der Lichtverteilung in eine Fokusebene 110, 510, 710, 1010. Erfindungsgemäß ist das abbildende optische System 106, 906, 1006 derart ausgestaltet, dass eine Pupille des abbildenden optischen Systems 106, 906, 1006 zwischen 2 und 25 mm vor oder hinter der Fokusebene 110, 510, 710, 1010 ausgebildet ist.

Automated surgical instruments and processes

An Automated Surgical instrument is disclosed that is computer controlled and provided with a high degree of autonomy for performing automated procedures within humans and other animals. It may be mobile under its own control and may include a plurality of means to disrupt tissue including lasers and water jets. A method of providing barriers to prevent unwanted damage to tissue is also described. The instrument may be used to construct both artificial and biological structures in-vivo by taking advantage of 3D printing techniques made available by the flexible laser system disclosed, a selection of micro tools, and raw material delivery to the worksite for printing to the target area. The use of vibration generated electricity may avoid the need for wires or batteries. A particular embodiment for automated cataract surgery is described.

PREPARATION OF EYE RAGS FOR LASER WELDING PROCESS

LASER CORRECTION OF SEHFEHLERN AT THE NATURAL EYEPIECE

LASERSKALPELL

DEVICE FOR REMOVING FROM LENS TURBIDITY FABRIC

EQUIPMENT FOR THE EYE SURGERY.

DEVICE FOR THE TREATMENT OF TURBIDITY AND/OR HARDENING AN UNOPENED EYE

FOOT PEDAL FOR MEDICAL INSTRUMENT

SURGICAL LASER PROBE

Laser system for performing ophthalmological procedures

The invention relates to a laser system (1) for performing ophthalmological procedures, comprising a pulse laser (3) for emitting laser pulses, a focusing optical unit (5) for producing at least one focal point in the front region (17) of an eye (18) of a patient, a deflecting device (6) for varying the position of the focal point in the front region (17) of the eye (18) of the patient, and a control unit for controlling the deflecting device (6). The pulse layer (3) has a pulse duration in the nanosecond range, and the laser system (1) is designed as a hand-held device.

Lens barrier to facilitate automated surgery

A barrier for insertion into the space or potential space between the lens of an eye and the lens capsule of the eye. It may be a protective barrier to mitigate damage from laser light or other targeted electromagnetic radiation. It may be a defining barrier that facilitates machine recognition of boundaries. The barrier may perform both functions. The use of the barrier is optimised for use with automated systems for lens removal, including the intraocular probe disclosed in this specification. Fig 5 Fi262 Fig7 19a /A19b Fig 7 ...

Robust laser cutting methods for ophthalmic surgery

In a first aspect, the present invention provides an apparatus for performing an ocular laser surgical procedure, comprising: a laser configured to emit a beam; optical elements configured to focus the beam emitted by the laser at a desired position on an eye of a patient; and a controller configured to control the laser and the optical elements, wherein the controller is configured to use a cutting pattern to control the laser and the optical elements, the cutting pattern comprising a vertical side cut thereby creating a flap, the vertical side cut traversing a plurality of generally diagonal paths, the cutting pattern further comprising a plurality of photodisruption points forming a generally circular cut around a periphery of a capsule of the eye, the cutting pattern extending from a start point continuously in an angular direction to an end point covering an angular range greater than 360 degrees, a starting portion and an ending portion of the cutting pattern overlapping with each ...

Surgical instrument for minimally invasive aspiration of tissue

Systems and methods for combined Femto-Phaco surgery

Systems and methods are described for a combined Femto and Phaco surgical system built into a single housing. The system advantageously permits each of the Femto device and Phaco surgical tray to be rotated out of the way or into the position without requiring movement of a patient. Thus, a user can switch between Femto and Phaco surgical procedures without movement of the patient.

Apparatus and processes for preventing or delaying one or more symptoms of presbyopia

Apparatus for non or minimally disruptive photomanipulation of an eye

Controlled ocular lens regeneration

Laser assisted cataract surgery

Laser assisted cataract surgery methods and devices utilize one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may be applied to the anterior lens capsule to facilitate laser thermal separation of tissue along a treatment beam path on the lens capsule. Relative or absolute reflectance from the eye, and optionally from a surgical contact lens, may be measured to confirm and optionally quantify the presence of the light absorbing agent, before the treatment beam is applied.

Confocal detection to minimize capsulotomy overcut while dynamically running on the capsular surface

Embodiments of this disclosure disclose an imaging system, including an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The beam source generates an electromagnetic radiation beam. The detection assembly generates a signal indicative of an intensity of a portion of the electromagnetic radiation beam reflected from the focal point location. A subsequent focal point of the electromagnetic radiation beam may be adjusted per the measured intensity signal. In some embodiments, an intensity signal below a lower threshold value may suggest a depth increase for a subsequent focal point. An intensity signal above an upper threshold value may suggest a depth decrease for a subsequent focal point. And, an intensity signal between the lower and upper thresholds may suggest a depth be maintained for a subsequent focal point. The focal point may be adjusted after each pulse or after a plurality of pulses.

System, interface devices, use of the interface devices and method for eye surgery

The laser system for eye surgery comprises the eye -surgical laser apparatus having optical components for providing pulsed focused laser radiation with radiation properties matched to the generation of photodisruptions in human eye tissue and with a control unit for positional control of the radiation focus of the laser radiation, the control unit being designed for executing various control programs that represent various types of incision figure; and a set of interface devices, each of the interface devices including a contact body that is transparent to the laser radiation, with an abutment face for abutment against an eye to be treated, and also a coupling portion for detachable coupling of the interface device onto a counter- coupling portion of the laser apparatus, the interface devices of the set differing by virtue of a differing optical effect on the laser radiation provided in the laser apparatus.

Optical imaging and measurement systems and methods for cataract surgery and treatment planning

An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

Multiple depth optical coherence tomography system and method and laser eye surgery system incorporating the same

An OCT system for imaging multiple depth positions includes a light source, a sample arm and two or more reference arms. The sample arm propagates light to the object and directs object return light having a first return light beam from a first position and a second return light beam from a second position, the second return light having a dispersion level higher than the first return light beam by a dispersion difference amount. The first and second reference arms produce light beams having substantially the same dispersion as the first and second return light beams, respectively. The optical pathway combines all of the object return light and the reference light beams. An OCT detector measures the resulting interferogram. Imaging information is obtained for both the first position and the second position based on the dispersion difference amount.

Sub-nanosecond laser surgery system utilizing multiple pulsed laser beams

A system for laser ophthalmic surgery includes: a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam. The first treatment laser beam has a pulse energy of 10 to 500 µJ. The second pulsed laser beam has a second pulse energy of about 0.1 to 10 µJ, lower than the first treatment laser beam. An optical system focuses the first treatment laser beam to a first focal spot and directs the first focal spot in a first treatment pattern into a first intraocular target. The optical system also focuses the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into a second intraocular target. The first intraocular target and second intraocular target are different.

Devices and methods for the removal of lenticular tissue

An exemplary surgical device includes a shaft with a lumen defined therethrough and an element movable from a stored position to a deployed position in which a larger portion of the element extends out of the distal end of the lumen; wherein motion from the stored position to the deployed position causes a first leg of the element to advance distally relative to the distal end of the shaft, and causes a second leg of the element to move proximally relative to the distal end of the shaft.

Laser system and method for performing and sealing corneal incisions in the eye

There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined self-sealing incisions in the cornea. The systems, apparatus and methods further provide laser systems that can provide these incisions in conjunction with the removal and replacement of the natural human crystalline lens.

Patient interface for ophthalmologic diagnostic and interventional procedures

One embodiment is directed to a patient interface system for ophthalmic intervention on an eye of a patient, comprising: a housing; an optical lens coupled to the housing and having an optical axis; a eye surface engagement assembly coupled to the housing and comprising an inner seal having an inner seal diameter and being configured to circumferentially engage the eye, an outer seal having an outer seal diameter and being configured to circumferentially engage the eye, and a tissue migration bolster structure configured to be positioned circumferentially between the inner and outer circumferential seals and to prevent migration of tissue of the eye toward the eye surface engagement assembly when a vacuum load is applied within the assembly to cause vacuum engagement of the inner and outer seals against the eye.

Laser methods and systems for the aligned insertion of devices into a structure of the eye

LASER METHODS AND SYSTEMS FOR THE ALIGNED INSERTION OF DEVICES INTO A STRUCTURE OF THE EYE Abstract Systems, methods and apparatus for replacement of cataractous lenses, the insertions of devices into the eye, and the alignment of IOLs, including toric OLs. Systems, methods and apparatus for forming laser cut capsulotomies having alignment nubs that are aligned with an astigmatic axis of the eye.

OPTICAL SYSTEM WITH MOVABLE LENS FOR OPHTHALMIC SURGICAL LASER

An eye-surgical laser system includes a laser source, to generate a laser beam, an XY scanner, to scan a focal spot of a received laser beam in an XY direction essentially transverse to an optical axis of the laser system, and a lens group, disposed in the optical path between the laser source and the XY scanner, to receive the laser beam generated by the laser source, to precompensate an aberration of the laser beam, and to forward the precompensated laser beam to the XY scanner, the lens group having a movable lens, movable in a Z direction along an optical axis.

OPTICAL SYSTEM FOR OPHTHALMIC SURGICAL LASER

An ophthalmic laser system includes a laser source, to generate a pulsed laser beam, an XY scanner, to receive the pulsed laser beam, and to output an XY-scanning beam, scanned in two directions essentially transverse to an optical axis, and a multi-functional Z scanner, to receive the XY-scanning beam, to output an XYZ-scanning beam, having a numerical aperture NA and a focal spot in a target region, and to modify the numerical aperture NA essentially independently from scanning a Z focal depth of the focal spot along the optical axis.

OPTICAL SYSTEM FOR OPHTHALMIC SURGICAL LASER

This invention relates to a system for surgery of the anterior segment of the eye with a femtosecond laser, more particularly to embodiments minimizing optical distortions of the laser beam while scanning and focusing the laser beam into the eye. A laser system for ophthalmic surgery includes a laser source, to generate a pulsed laser beam, an XY scanner, to receive the pulsed laser beam, and to output an XY-scanning beam, scanned in two directions transverse to a Z axis. a Z scanner, to receive the XY-scanning beam, and to output an XYZ-scanning beam. scanned in addition along the Z axis, the Z scanner including a first lens group to output a beam having an intermediate focal plane, and a movable lens group to receive the beam through the intermediate focal plane and to collimate the beam in a variable manner, and an objective to receive the collimated beam from the Z scanner and to focus the beam into a focal spot in a target region.

CONTROL DEVICE FOR A SURGICAL LASER

The invention relates to, preferably surgical lasers and control devices thereof, in addition to methods for treating a transparent material, in particular an eye lens and/or horny skin, and in particular for the treatment of presbyopia.

SYSTEMS AND METHODS FOR TREATING OCULAR DISEASE WITH AN INTRAOCULAR LENS AND REFRACTIVE INDEX WRITING

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method of treating an ocular disease of a subject having an implanted intraocular lens (IOL) includes determining visual needs of a subject that are associated with an ocular disease of the subject determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, and applying the plurality of pulses of radiation to the one or more selected areas of the IOL.

HIGH SPEED TRACKING OF IOL DURING REFRACTIVE INDEX MODIFICATION

During a process of refractive index modification of an intraocular lens (IOL) using an ophthalmic laser system, optical position monitoring of the IOL is performed by a video camera system viewing the top surface of the IOL. Fiducials are incorporated into the IOL at manufacture, or created in-vivo with laser. The monitoring method employs a defined area of interest (AOI) to limit the number of pixels to be analyzed, to achieve adequately high acquisition speed. In one example, the AOI contains 5 camera scan line segments, each line segment having sufficient pixels to create a stable amplitude signature. Successive frames of the AOI are analyzed to detect movement of the fiducial and/or to determine whether the fiducial has been lost.

APPARATUS FOR CUTTING A HUMAN OR ANIMAL TISSUE COMPRISING AN OPTICAL COUPLER

La présente invention concerne un appareil découpe incluant - un laser femtoseconde (1), - un système de mise en forme (2) en aval du laser femtoseconde (1), pour former un faisceau LASER modulé en phase, - un scanner optique de balayage (4) en aval du système de mise en forme (2), - un système optique de focalisation (5) en aval du scanner optique de balayage (4), - une unité de commande (6) permettant de piloter le système de mise en forme (2), le scanner optique de balayage (4) et le système optique de focalisation (5), remarquable en ce que l'appareil comprend en outre un coupleur optique (3) entre le laser femtoseconde (1) et le système de mise en forme (2), le coupleur optique (3) incluant une fibre optique à cristal photonique pour le filtrage du faisceau LASER modulé en phase (21) issu du système de mise en forme (2).

DEVICES AND METHODS FOR OCULAR SURGERY

A surgical device for cutting a lens within a capsular bag of an eye. Related methods, systems, and devices are also provided.

SYSTEM AND METHOD FOR IMPROVING THE ACCOMMODATIVE AMPLITUDE AND INCREASING THE REFRACTIVE POWER OF THE HUMAN LENS WITH A LASER

A system and method for increasing the amplitude of accommodation and/or changing the refractive power of lens material of a natural crystalline lens is provided. Generally, there is provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of patterns results in the increased accommodative amplitude and/or refractive poser of the lens. There is further provided a system and method of treating presbyopia by increasing both the flexibility of the human lens and the depth of field of the eye.

SUB-NANOSECOND LASER SURGERY SYSTEM UTILIZING MULTIPLE PULSED LASER BEAMS

A system for laser ophthalmic surgery includes: a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam. The first treatment laser beam has a pulse energy of 10 to 500 µJ. The second pulsed laser beam has a second pulse energy of about 0.1 to 10 µJ, lower than the first treatment laser beam. An optical system focuses the first treatment laser beam to a first focal spot and directs the first focal spot in a first treatment pattern into a first intraocular target. The optical system also focuses the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into a second intraocular target. The first intraocular target and second intraocular target are different.

APPARATUS, INTERFACE UNIT, SUCTION RING AND METHOD TO MONITOR CORNEAL TISSUE

An apparatus and a method for cutting or ablating corneal tissue of an eye provide for detection of electromagnetic radiation exiting the eye (18). A detector (36) is provided and coupled to a computer controlling the cutting or ablating laser radiation so that a two- or three-dimensional image of radiation (26, 28) exiting the eye can be generated.

SYSTEM AND METHOD FOR SCANNING A BEAM OF ULTRA-SHORT PULSE LIGHT

An embodiment of a scanning optical system comprises: an optical source providing a beam of pulsed light of ultra-short pulse duration; a deflector for deflecting the beam through a scan angle; a lens system including a focusing objective for focusing the deflected beam; a dispersion compensating device for reducing dispersion-related distortion of a pulse of the beam by the lens system, the dispersion compensating device including a deformable, dispersive mirror and an actuator device for the mirror; and a controller for controlling the actuator device to change a shape of the mirror in accordance with the scan angle.

OPHTHALMIC RANGE FINDING

Systems and methods for analyzing the anatomy of a patient's eye with circular or rotated polarized laser beams, or with laser beams of different wavelengths are disclosed. One system includes a polarization beam-splitter and a quarter-wave plate, wherein the quarter-wave plate is configured to circularly rotate a laser beam received from a laser that is transmitted and passes through the polarization beam-splitter, and to transform a circularly rotated back-reflected beam to a linearly polarized laser beam that is perpendicular to the beam that was transmitted through the polarization beam-splitter. Substantially all of the back-reflected beam is directed to a photo-detector for analysis. A Faraday rotator subsystem may be substituted for a polarization beam-splitter. An optical system including a laser that generates a laser beam of a first wavelength for therapeutic treatment, and another laser that generates a laser beam of a second wavelength for measurement is also disclosed.

OPTICAL COHERENCE TOMOGRAPHIC SYSTEM FOR OPHTHALMIC SURGERY

Optical imaging techniques and systems provide high-fidelity optical imaging based on optical coherence tomographic imaging and can be used for optical imaging in ophthalmic surgery and imaging-guided surgery. One method for imaging an eye includes positioning the eye relative to a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system, the eye having a first and a second structure, and imaging the eye with the SD-OCT imaging system by selecting one of a direct image and a mirror image of the first eye-structure and generating a first image-portion corresponding to the selected image of the first eye-structure, selecting one of a direct image and a mirror image of the second eye-structure and generating a first image-portion corresponding to the selected image of the second eye-structure, and suppressing the non-selected images of the first and second structures.

SYSTEM FOR ABLATING AN EYE LENS

Systems and methods are provided for ablating a lens of an eye. An access incision is made through outer eye tissue to access the lens. A laser tool is inserted through the access incision. Electromagnetic energy is focused using the inserted laser tool to ablate a portion of the lens, where said ablation breaks the lens into a plurality of pieces for removal from the eye.

APPARATUS AND METHOD FOR OPERATING A REAL TIME LARGE DIOPTER RANGE SEQUENTIAL WAVEFRONT SENSOR

An apparatus including a position sensing detector (122) and a processing system (710, 750), with the processing system (710, 750) configured to determine axis of astigmatism and cylinder and sphere diopter values of a subject eye.

APPARATUS AND METHOD FOR OPERATING A REAL TIME LARGE DIOPTER RANGE SEQUENTIAL WAVEFRONT SENSOR

A wavefront sensor using a calibration wave generator (199/299) to calculate correction factors to be applied to ratiometric combinations of position sensor (122) output signals to determine real centroid deflection values.

CASE OF LIGHT FOR EYE EXAMINATION DEVICES.

A control apparatus for a laser system and laser system and method for controlling the laser system.

Die Erfindung betrifft eine Steuerungsvorrichtung für ein Lasersystem mit einem Laser zum Einbringen von Schnitten in eine Linse (21) eines menschlichen oder tierischen Auges (20), die eingerichtet ist, einen Fokuspunkt eines Laserstrahls des Lasers innerhalb der Linse anzuordnen und zu verlagern, wobei der Fokuspunkt für mindestens einen Schnitt (21.1) zum Segmentieren der Linse in einzelne Segmente (21.1a) verlagerbar ist und gemäss einem definierbaren Schnittmuster zum weiteren Fragmentieren der Linse verlagerbar ist; wobei die Steuerungsvorrichtung eingerichtet ist, ein einzelnes der Segmente zu bestimmen und den Fokuspunkt zum weiteren Fragmentieren innerhalb des bestimmten Segments in radialer Richtung maximal bis zu einem Abstand grösser Null zu einem Rand der Linse zu verlagern. Ferner betrifft die Erfindung ein Verfahren zum Steuern des Lasersystems.

A control apparatus for a laser system and laser system and method for controlling the laser system.

Die Erfindung betrifft eine Steuerungsvorrichtung für ein Lasersystem mit einem Laser zum Einbringen von Schnitten in eine Linse (21) eines menschlichen oder tierischen Auges (20), die eingerichtet ist, einen Fokuspunkt eines Laserstrahls des Lasers innerhalb der Linse anzuordnen und zu verlagern, wobei der Fokuspunkt für mindestens einen Schnitt (21.1) zum Segmentieren der Linse in einzelne Segmente (21.1a) verlagerbar ist und gemäss einem definierbaren Schnittmuster zum weiteren Fragmentieren der Linse verlagerbar ist; wobei die Steuerungsvorrichtung eingerichtet ist, ein einzelnes der Segmente zu bestimmen und den Fokuspunkt zum weiteren Fragmentieren innerhalb des bestimmten Segments in radialer Richtung maximal bis zu einem Abstand grösser Null zu einem Rand der Linse zu verlagern. Ferner betrifft die Erfindung ein Verfahren zum Steuern des Lasersystems.

Vorrichtung zur Ablationsbearbeitung von ophthalmologischem Implantationsmaterial.

Die Erfindung betrifft eine Vorrichtung (1) zur Ablationsbearbeitung von ophthalmologischem Implantationsmaterial (2), welches durch wasserhaltiges Grundmaterial gebildet ist, umfassend eine Laserquelle (11), die eingerichtet ist, einen gepulsten Laserstrahl (L) mit einer Bearbeitungswellenlänge im Ultraviolett-Wellenbereich zu erzeugen, wobei die Bearbeitungswellenlänge grösser als 193nm ist und im Grundmaterial des Implantationsmaterials (2) einen höheren Absorptionsgrad des Laserstrahls (L) bewirkt als der Absorptionsgrad des Laserstrahls (L) im Wasser des Implantationsmaterials (2).

APPARATUS HAS LASER AS AN OPHTHALMIC SURGERY

OPTICAL SYSTEM FOR OPHTHALMIC SURGICAL LASER

método de determinação para determinar um valor mínimo de energia laser e dispositivo de determinação

Apparatus and method for operating a real time large diopter range sequential wavefront sensor

An wavefront including a light source for providing a light beam to illuminate a subject eye and a beam deflecting to deflect the light beam to compensate transverse movement of the subject eye. A second beam deflecting element scans the beam around a small portion of the retina to dissipate energy.

A system for laser photoablation within a lens

The present invention provides a method for ablating a presbyopic lens for restoring accommodation in human eye and a system thereof wherein a laser beam is directed obliquely to carry out multiple photoablations in circular way within the lens behind the iris and preferably near the edge or equator of the lens and/or in the vicinity of zonules to re-establish accommodation of the lens lost due to presbyopia.

ROBUST LASER CUTTING METHODS FOR OPHTHALMIC SURGERY

A method and apparatus for performing ophthalmic laser surgery using a pulsed laser beam is provided. The method includes establishing an initial cutting pattern comprising a plurality of original photodisruption points, establishing an enhanced cutting pattern comprising a plurality of enhanced photodisruption points selected to decrease potential adverse effects due to patient movement and having increased density over a fixed area as compared with the plurality of original photodisruption points, and performing an ocular surgical procedure according to the enhanced cutting pattern. Enhanced cutting patterns may include circular cuts around the periphery of a capsule, vertical side cuts for lens fragmentation, raster lamellar cuts, and grid lamellar cuts. Each photodisruption point in the initial cutting pattern and the enhanced cutting pattern comprises a laser target point.

APPARATUS AND METHOD FOR OPERATING A REAL TIME LARGE DIOPTER RANGE SEQUENTIAL WAVEFRONT SENSOR

A wavefront sensor includes a light source (172) configured to illuminate a subject eye, a detector (122), a first beam deflecting element (112/412) configured to intercept a wavefront beam returned from a subject eye when the subject eye is illuminated by the light source (172) and configured to direct a portion of the wavefront from the subject eye through an aperture (118/418) toward the detector (122) and a controller, coupled to the light source (172) and the first beam deflecting element (112/412), configured to control the first beam deflecting element (112/412) to deflect and project different portions of an annular ring portion (444/494) of the wavefront from the subject eye through the aperture (118/418) and further configured to pulse the light source (172) at a firing rate to sample selected portions of the annular ring (118/418) at the detector.

APPARATUS AND METHOD FOR OPERATING A REAL TIME LARGE DIOPTER RANGE SEQUENTIAL WAVEFRONT SENSOR

An apparatus including a wavefront sensor including a light source (172) configured to illuminate a subject eye, a detector (122), an image sensor (162) configured to output an image of the subject eye, a first beam deflecting element (112) configured to intercept a wavefront beam returned from a subject eye when the subject eye is illuminated by the light source (172) and configured to direct a portion of the wavefront from the subject eye through an aperture (118) toward the detector (122), and a controller coupled to the light source (172), the image sensor (162) and the beam deflecting element (112), configured to process the image to determine transverse movement of the subject eye and to control the beam deflecting element (112) to deflect and project through the aperture (118) portions of an annular ring portion of the wavefront and further configured to pulse the light source (172) at a firing rate to sample selected portions of the annular ring at the detector (122), to process ...

APPARATUS, SYSTEMS AND TECHNIQUES FOR INTERFACING WITH AN EYE IN LASER SURGERY

Apparatus, techniques and systems are provided for interfacing with an eye in laser surgery.

METHOD OF LASER PHOTOABLATION OF LENTICULAR TISSUE FOR THE CORRECTION OF VISION PROBLEMS

Abstract not available! Abstract of correspondent: US2002103478 A method for the laser photoablation of ocular lens tissue comprises the steps of determining a volume of the lens tissue to be photoablated and directing a pulsed, infrared laser beam at the volume with an amount of energy effective for photoablating the determined region without causing substantial damage to surrounding tissue regions. The laser beam is initially directed at a focal point below an anterior surface of the ocular lens and such focal point is moved towards the ocular lens anterior surface in order to ablate the determined volume. The laser is preferably an Nd:YLF laser operating at a frequency of about 1053 nanometers and a pulse repetition rate of about 1000 Hertz with a pulse width of about 60 picoseconds. Each pulse has an energy of about 30 microjoules. The laser operates with a focused beam diameter of about 20 microns and operates with a "zone of effect" of no greater than about 50 microns. The method ...

SYSTEM AND METHOD FOR FEMTO-FRAGMENTATION OF A CRYSTALLINE LENS

A system and method for performing a femto-fragmentation procedure on tissue in the crystalline lens of an eye requires that a laser beam be directed and focused to a focal point in the crystalline lens of the eye. The focal point is then guided, relative to an axis defined by the eye, to create a segment cluster by causing Laser Induced Optical Breakdown (LIOB) of tissue in the crystalline lens. The resultant segment cluster includes a plurality of contiguous, elongated segments in the crystalline lens that are individually tapered from an anterior end-area to a posterior end-area. Specifically, this is done to facilitate the removal of individual segments from the segment cluster in the crystalline lens.

Method of preventing capsular opacification and fibrosis utilizing an accommodative intraocular lens implant

A method of preventing capsular opacification and fibrosis utilizing an accommodative intraocular lens implant, which includes the steps of removing a cortex and nucleus of a natural lens containing a cataract from a lens capsule of an eye of a patient; applying a photosensitizer inside the lens capsule so that the photosensitizer permeates a portion of the lens capsule, the photosensitizer facilitating cross-linking of the tissue in the portion of the lens capsule; irradiating the portion of the lens capsule so as to activate cross-linkers in the tissue in the portion of the lens capsule, thereby damaging the remaining lens epithelial cells in the lens capsule with the irradiated light so as to prevent capsular opacification and fibrosis; and injecting a transparent polymer into the lens capsule of the eye in order to form an accommodative intraocular lens for replacing the cortex and nucleus of the natural lens.

LASER INSTRUMENT FOR EYE THERAPY

A laser instrument for therapy on the human eye, designed for surgery of the cornea, the sclera, the vitreous body or the crystalline lens, especially suitable for use in immediate succession with other instruments for eye diagnosis or eye therapy, in such a way that during the alternating use of the various instruments, the eye or at least the patient preferably remains in a predetermined position and alignment within one and the same treatment area.

APPLICATOR AND DEVICE FOR CELL TREATMENT

An applicator configured for cell treatment with pressure pulses has a hollow needle with a wall, which encloses a cavity and has a closed-off design at a closed-off end. A target is arranged or formed at the closed-off end on the inner side of the wall and a laser radiation emitter for emitting preferably pulsed laser radiation is arranged in the cavity of the hollow needle, at a distance from the target. The laser radiation emitter is arranged so that the emerging laser radiation impinges directly on the target through an interspace situated between the laser radiation emitter and the target. Under the formation of a plasma, at least one pressure pulse can be generated at the target by the target being impinged upon by laser radiation from the laser radiation emitter. The wall of the hollow needle has a lateral emergence opening for the emergence of the pressure pulse.

Liquid filled index matching device for ophthalmic laser procedures

There is provided a device for use as an interface between a laser surgery device and the eye of a patient. The device is filled with a liquid that matches the index of refraction of the eye. The device further has a curved lens that follows the curvature of the outer surface of the patient's eye. In this manner the interface device, through which the laser beam must travel, has essentially the same index of refraction as the eye.

OPHTHALMOLOGICAL LASER THERAPY SYSTEM

An ophthalmological laser therapy system having an appliance base and an appliance head, displaceable relative to one another by translational movement and having a laser device and to a corresponding method. A laser pivot arm is fastened to the appliance head pivotable about a horizontal first axis. The laser pivot arm is encompassed by a pivot arm housing, which is fastened in a separately pivotable manner on the appliance head in coaxial fashion relative to the laser pivot arm and/or by virtue of an examination pivot arm with an examination device, defining an examination volume, being fastened to the appliance head pivotable about a second axis, wherein both axes are arranged such that a work volume of a laser beam, when the laser pivot arm is in a work position, is a partial volume of the examination volume, when the examination pivot arm is in a work position.

DEVICES AND METHODS FOR THE REMOVAL OF LENTICULAR TISSUE

An exemplary surgical device includes a shaft with a lumen defined therethrough and an element movable from a stored position to a deployed position in which a larger portion of the element extends out of the distal end of the lumen; wherein motion from the stored position to the deployed position causes a first leg of the element to advance distally relative to the distal end of the shaft, and causes a second leg of the element to move proximally relative to the distal end of the shaft.

PRODUCING CUT SURFACES IN A TRANSPARENT MATERIAL BY MEANS OF OPTICAL RADIATION

A method for producing a cut surface in a transparent material using optical radiation. A laser device separates the material using optical radiation and includes an optical unit focussing the radiation along an optical axis into an image field defining an image-field size. A focal position is adjusted transversely along the axis, producing a cut surface extending substantially parallel to the axis and, in projection along the axis, is a curve having a maximum extent. The focus is displaced by adjustment of the focal position along a trajectory curve lying in the cut surface. The cut surface has a maximum extent which is greater than the image-field size. The focal position is moved transverse to the axis along the curve. The image field is displaced transversely, and the focal position is adjusted in an oscillating fashion along the axis on the curve between an upper and lower axial focus position.

ILLUMINATION CHOPPER

The present invention provides an illumination chopper which allows a user to operate on the nucleus of a crystalline lens with a small piece while securing visibility through a chopper which is mounted at one end of an illuminator to form a predetermined angle with the illuminator.

Laser-assisted thermal separation of tissue

A laser-assisted method for fully or partially separating tissue such as collagen containing tissue is provided. In one embodiment, the method pertains to a capsulorhexis whereby the laser-assisted method is applied to the lens capsule. A light-absorbing agent is added into or onto the tissue. A light beam with a wavelength capable of being absorbed by the light absorbing agent is then directed at the tissue to cause a thermal effect at the tissue following a predetermined closed curve with the goal to avoid irregularity or potential tears in the resulting rim of the tissue.

OPTICAL SYSTEM FOR A LASER THERAPY INSTRUMENT

An optical system for a laser therapy instrument for the application of laser radiation on and in the eye, includes a femtosecond laser, an objective. The objective or at least one lens or lens group of the objective is shiftable in the direction of the optical axis being intended for shifting of the focus position from the region of the cornea to the region of the crystalline lens and vice versa. The optical system may include at least two optical assemblies designed for the axial variation of the focus of the therapeutic laser radiation, with the focus variation range Δz differing between the individual assemblies and a changing device, designed for the insertion of any one of these assemblies into the therapeutic laser beam path at a time.

Femtosecond laser system for precise processing of material and tissue

Die vorliegende Erfindung betrifft eine Vorrichtung (1) zur präzisen Bearbeitung von Material (90), insbesondere organischem Material, umfassend ein gepulstes Lasersystem (10) mit einer Strahlquelle (15), wobei ein cavity-dumped fs-Oszillator (11) als Strahlquelle vorgesehen ist.

SYSTEM AND METHOD FOR PROVIDING LASER SHOT PATTERNS TO THE LENS OF AN EYE

SYSTEMS AND METHODS FOR DISRUPTION OF AN EYE LENS

Improved ophthalmic surgical laser

A pulsed laser apparatus for providing controlled ablation of organic material in an object at a selected ablation point of interaction by means of generated laser pulses. The apparatus includes a laser for emitting a beam of pulses having a duration in the range of about 0.01 picoseconds to about 2 picoseconds. The apparatus comprises applanting device in contact with the object providing a positional frame of reference for the laser beam thereby determining an ablation point of interaction within the object.

METHOD AND DEVICE FOR MEASURING IMAGING ERRORS IN THE HUMAN EYE

眼球手術の装置と方法

... 眼部の前眼房であり且つ白内障レンズの近傍に挿入するための光学プローブは、光源60とその光源からプローブに光放射を伝える光導波路100とにより構成される。光放射はパルス状に形成され、その繰り返しレート、波長および光エネルギーは、切断領域内の白内障レンズに十分な切断誘導損傷をもたらし、またアコースティック領域に十分なアコースティック誘導損傷をもたらすとともに、そのアコースティック領域が切断領域より十分に大きな寸法となるように選択される。アコースティック領域は、切断領域から放射する振動波を発生させ、その振動波が白内障レンズの硬質核質材内を、その核質材に微細な割れ目が生じるように伝搬させることにより形成される。微細な割れ目を有するレンズ材は、その微細な割れ目が形成される以前と較べ、はるかにレーザー・パルスに反応するので、そのレーザー・パルスの印加に応答して、硬質核質材は容易に微細な粒子に分解される。 ...

ОПТИЧЕСКАЯ СИСТЕМА ДЛЯ ОФТАЛЬМОЛОГИЧЕСКОГО ХИРУРГИЧЕСКОГО ЛАЗЕРА

Группа изобретений относится к медицинской технике. Офтальмологическая лазерная система включает источник лазерного излучения для генерирования импульсного лазерного луча; XY-сканер для приема импульсного лазерного луча и для испускания сканирующего по направлениям XY луча, производящего сканирование по двум направлениям, по существу поперечным оптической оси; и многофункциональный Z-сканер, предназначенный для приема сканирующего по направлениям XY луча и для испускания сканирующего по направлениям XYZ луча, причем сканер имеет числовую апертуруи фокальное пятно в целевой области и предназначен для модификации числовой апертуры,по существу независимо от сканирования фокальной глубины Z фокального пятна по оптической оси. Группа изобретений обеспечивает выполнение хирургических вмешательств на хрусталике глаза. 3 н. и 33 з.п. ф-лы, 19 ил., 12 табл.

ЛЕЧЕБНЫЙ ЛАЗЕР С ЗЕРКАЛЬНЫМ ОТРАЖАТЕЛЕМ И ЗАЩИТНОЙ БЛОКИРОВКОЙ

Группа изобретений относится к медицине. Офтальмологическая лазерная система для генерации первого пучка с первой длиной волны на первом пути пучка и второго пучка со второй длиной волны на втором пути пучка, и направляющая оптика для избирательного направления первой длины волны или второй длины волны по пути лечебного пучка. Офтальмологическая лазерная система содержит зеркальный коаксиальный осветитель, содержащий зеркальный отражатель, перемещаемый на оси из положения вне пути лечебного пучка в положение на пути лечебного пучка, чтобы направлять подсветку по пути подсветки, соосному с путем лечебного пучка, и защитную блокировку, делающую возможным работу офтальмологической лазерной системы только по первому пути пучка, если зеркальный коаксиальный осветитель находится в первом положении, и делающую возможным работу офтальмологической лазерной системы либо по первому пути пучка, либо по второму пути пучка, если зеркальный коаксиальный осветитель не находится в первом положении. Применение ...

УСТРОЙСТВА И СПОСОБЫ ДЛЯ УДАЛЕНИЯ ХРУСТАЛИКОВОЙ ТКАНИ

Изобретение относится к медицинской технике, в частности к экстракции хрусталиковой или другой ткани в офтальмологической хирургии. Хирургическое устройство для разрезания хрусталика внутри капсульного мешка глаза содержит стержень и рассекающий элемент. Стержень имеет дистальный конец и просвет, образованный через стержень. Просвет имеет продольную ось и дистальный конец. Рассекающий элемент имеет первую сторону и вторую сторону. Рассекающий элемент выполнен с возможностью перемещения относительно стержня из первой конфигурации введения в направлении второй конфигурации захвата, в которой больший участок рассекающего элемента выдвинут из дистального конца просвета. По меньшей мере участок рассекающего элемента расположен внутри просвета, когда находится в первой конфигурации введения. Рассекающий элемент в первой конфигурации введения и дистальный конец стержня выполнены такого размера, чтобы вводить их в переднюю камеру глаза через разрез. Перемещение из первой конфигурации введения в ...

ВНУТРИХИРУРГИЧЕСКОЕ ИЗОБРАЖЕНИЕ ОПТИЧЕСКОЙ КОГЕРЕНТНОЙ ТОМОГРАФИИ ОПЕРАЦИИ ПО УДАЛЕНИЮ КАТАРАКТЫ

СПОСОБ И УСТРОЙСТВО ДЛЯ НЕРАЗРУШАЮЩЕЙ ИЛИ МИНИМАЛЬНО РАЗРУШАЮЩЕЙ СВЕТОВОЙ ОБРАБОТКИ ГЛАЗА

... 1. Система для неразрушающей или минимально разрушающей световой обработки хрусталика и/или его составляющих, в совокупности или выборочно, глаза животного или человека, содержащая: ! a) лазерную систему для излучения по меньшей мере одного воздействующего лазерного луча в диапазоне длин волн 700-1000 нм или 100-1500 нм; ! b) средства фокусировки указанного воздействующего лазерного луча на выбранном участке хрусталика и/или его составляющих, в совокупности или выборочно, там, где предполагается производить воздействие; ! c) средства обеспечения импульсного режима указанного воздействующего лазерного луча; ! d) средства измерения одного или нескольких типов излучения от указанного выбранного участка; ! e) средства обработки результатов измерений указанного одного или нескольких типов излучения от указанного выбранного участка; ! f) средства регулировки по меньшей мере одного из следующих параметров указанного воздействующего лазерного луча: фокусировки, интенсивности, длины волны, ширины ...

ОПТИЧЕСКАЯ СИСТЕМА ФОКУСИРОВКИ АППАРАТА ДЛЯ РАЗРЕЗАНИЯ ТКАНИ ЧЕЛОВЕКА ИЛИ ЖИВОТНОГО

Hybrid ophthalmic interface apparatus and method of interfacing a surgical laser with an eye

Apparatus and methods are provided for interfacing a surgical laser with an eye using a patient interface device that minimizes aberrations through a combination of a contact lens surface positioning and a liquid medium between an anterior surface of the eye and the contact lens surface.

Apparatus and method for removing a lenticle from the cornea

An apparatus and method for removing a lenticle from the cornea. For this purpose, a device for liquefying the lenticle and a device for suctioning off the resulting fluid are provided. The lenticle is liquefied and the resulting fluid is then suctioned off.

Aberration control by corneal collagen crosslinking combined with beam-shaping technique

Corneal collagen crosslinking is used to alter a characteristic of the cornea, such as thickness or refractive index, to correct wavefront aberrations, including higher-order aberrations. A scanning laser or the like is used to perform the corneal collagen crosslinking by locally altering the optical path length (thickness, refractive index, or both).

Corneal treatment system and method

A system for bilateral or monocular photochemical cross-linking of corneal collagen employs selectable light in a selected wavelength band as the excitation source and riboflavin as the photosensitizer. The system has an illumination source which may have multi-spectral capability, light guides for delivery of light to the optical head for projection onto the corneal surface, selectable radiation patterns to accommodate individual corneal architecture, and red light phototherapy to limit apoptosis and accelerate healing time. Aiming beams provide alignment of the optical head to the patient cornea. A microprocessor-controlled rotary solenoid mechanical shutter provides discontinuous illumination for tissue reoxygenation, and devices and methods may be included for the in situ determination of oxygen utilization and the riboflavin content of the cornea.

Annular and other ablation profiles for refractive surgery systems and methods

Systems, methods, and computer program products are provided for the administration of annular and other ablation profiles during refractive surgery treatments. Basis data framework techniques enable the implementation of both circular and annular ablation profiles resulting in increased ablation efficiency when treating certain vision conditions. In some instances, systems or treatments involve the use of symmetric and asymmetric ablations shapes such as double spots, triple spots, quadruple spots, multiple spots, arc shapes, elliptical shapes, and the like.

Photochemical tissue bonding

Photochemical tissue bonding methods include the application of a photosensitizer to a tissue, e.g., cornea, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for wound repair, or other tissue repair.

Eye position registering and tracking

Embodiments of the invention refer to a system for registering and tracking the position of a person's eye, in particular for refractive ophthalmic surgery. According to embodiments, the system is structured such that eye images containing at least the iris and the pupil of the eye are made at a first wavelength of light and that eye images containing scleral blood vessels are made at a different second wavelength of light. The invention furthermore refers to a corresponding method for registering and tracking the position of a person's eye.

treatment planning method and system for controlling laser refractive surgery

Improved devices, systems, and methods for diagnosing, planning treatments of, and/or treating the refractive structures of an eye of a patient incorporate results of prior refractive corrections into a planned refractive treatment of a particular patient by driving an effective treatment vector function based on data from the prior eye treatments. The exemplary effective treatment vector employs an influence matrix which may allow improved refractive corrections to be generated so as to increase the overall accuracy of laser eye surgery (including LASIK, PRK, and the like), customized intraocular lenses (IOLs), refractive femtosecond treatments, and the like.

Device for ophthalmological laser surgery

An apparatus for ophthalmic laser surgery includes a contact surface for shaping abutment of an eye to be treated, a first radiation-source for making a treatment laser beam available, optical components for directing the treatment laser beam through the contact surface onto the eye and also a measuring device for measuring at least one corneal thickness dimension or/and positional dimension of the eye bearing against the contact surface, whereby the measuring device makes measured data available that are representative of the measured at least one thickness dimension or/and positional dimension. The measuring device preferably serves for positional surveying of the corneal posterior surface of the eye, whereby an electronic evaluating and control arrangement connected to the measuring device brings about a focus control of the treatment laser beam in a manner depending on the measured position of the posterior surface of the cornea.

Altering Iris Color

Techniques for altering iris pigment in a human or animal, thereby altering iris color of an iris from a first iris color to a second iris color, are provided. An apparatus includes at least one laser device and a masking device. Another apparatus includes at least one laser device and a contact lens. The at least one laser device can generate at least one beam to selectively remove iris pigment of at least one preselected pigment color from the iris.

Accommodation compensation systems and methods

Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

System and method for correcting astigmatism using multiple paired arcuate laser generated corneal incisions

A method for the reduction or elimination of astigmatism in an eye that includes an astigmatism axis, the method including determining an astigmatism axis of an eye and forming a first set of incisions in a cornea of the eye that are bisected by the astigmatism axis. The method including forming a second set of incisions in the cornea that are bisected by the astigmatism axis, wherein the first set of incisions and the second set of incisions reduce or eliminate astigmatism in the eye.

Method for modifying the refractive index of ocular tissues and applications thereof

A method for modifying a refractive property of ocular tissue in an eye by creating at least one optically-modified gradient index (GRIN) layer in the corneal stroma and/or the crystalline by continuously scanning a continuous stream of laser pulses having a focal volume from a laser having a known average power along a continuous line having a smoothly changing refractive index within the tissue, and varying either or both of the scan speed and the laser average power during the scan. The method may further involve determining a desired vision correction adjustment, and determining a position, number, and design parameters of gradient index (GRIN) layers to be created within the ocular tissue to provide the desired vision correction.

System and Method for Obviating Posterior Capsule Opacification

A system and method are provided for obviating Posterior Capsule Opacification (PCO) which require an Optical Coherence Tomography (OCT) device for imaging the interface surface between the posterior surface of an intraocular lens (IOL) and the capsular bag. Further, the OCT device is used to identify areas of relative opacity caused by a biological growth on the interface surface in the optical zone of the IOL. A laser unit is then used to direct the focal point of a femtosecond laser beam onto the areas of relative opacity to ablate the biological growth by Laser Induced Optical Breakdown (LIOB) to thereby obviate the PCO.

Methods and patterns for increasing amplitude of accommodations in a human lens

A method of treating a human eye, generally to correct vision, and preferably in one embodiment to increase the amplitude of accommodation of the lens. The method utilizes a laser to create a desired pattern within the lens. Various patterns for treating the eye lens are also disclosed.

Patient interface for ophthalmologic diagnostic and interventional procedures

An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.

Device for processing eye tissue by means of a pulsed laser beam

For processing eye tissue by means of a pulsed laser beam (L), an ophthalmological device comprises a projection optical unit for the focused projection of the laser beam (L) into the eye tissue, and a scanner system disposed upstream of the projection optical unit and serving for the beam-deflecting scanning of the eye tissue with the laser beam (L) in a scanning movement (s′) performed over a scanning angle along a scanning line (s). The projection optical unit can be tilted about an axis of rotation (q) running perpendicularly to a plane defined by the scanning line (s) and the optical axis (o) of the projection optical unit, the tilting of the projection optical unit bringing about a tilting of the scanning line (s) in said plane. The tilting of the scanning line (s) enables a displacement—dependent on the scanning angle—of the focus of the laser pulses projected into the eye tissue without vertical displacement of the projection optical unit.

Systems and methods for correcting high order aberrations in laser refractive surgery

Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.

System and method for ophthalmic surface based on objective quality estimation

Systems and methods for measuring a topography of an optical tissue surface of an eye are provided by combining a measured elevation of the surface with a priori information of the surface to provide an estimate of mean and covariance of post-measurement orthogonal polynomial sequence amplitudes associated with the surface, determining a variance of elevation of the surface from the estimate, and constructing the topography from the estimate of mean and covariance of post-measurement amplitudes based on a comparison of the variance of elevation of the surface with a pre-determined threshold. The a priori information includes an estimate of mean and covariance of pre-measurement orthogonal polynomial sequence amplitudes associated with the surface.

Apparatus for ophthalmological, in particular refractive, laser surgery

In an apparatus for ophthalmological, in particular refractive, laser surgery a pachymetric measuring device based on an optical-coherence interferometric measuring process is controlled in such a way that the position of the measuring beam emitted by the measuring device follows movements of the eye to be treated. The eye movements are registered by means of a camera of an eye-tracker. For the purpose of changing the position of the measuring beam, a partially transmitting deflecting mirror, via which the measuring beam is routed onto the eye, is movably, in particular tiltably, arranged.

Capsule friendly tips for phacoemulsification and for irrigation / aspiration

A surgical tool that includes a tip with a smooth, rounded edges and free of any sharp edges. The tip may have pores on its top, but none on the underside of its base. The distal end may have an open port with micro wires that form a Maltese cross shape. The distal end may be instead closed with protrusions spaced from each other by gaps or recesses.

Apparatus for treating eye tissue with laser pulses

An ophthalmological apparatus ( 1 ) for treating eye tissue ( 3 ) with laser pulses (P) comprises a laser source ( 100, an optical projection system ( 20 ) for projecting the laser pulses (P) onto the eye tissue ( 30 ), and a coupling part ( 12 ) for attaching mechanically to the optical projection system ( 20 ) an ophthalmological patient interface device ( 27 ) which is in contact with the eye ( 3 ) during treatment. The ophthalmological apparatus ( 1 ) further comprises a detector ( 13 ) for determining a device identifier ( 22 ) associated with the ophthalmological patient interface device ( 27 ), and a control module ( 14 ) for controlling the ophthalmological apparatus ( 1 ) using the device identifier ( 22 ). The detector makes it possible to use and detect different types of ophthalmological patient interface devices ( 27 ) and to adapt automatically the treatment of the eye tissue ( 30 ), depending on the ophthalmological patient interface device ( 27 ) that is presently attached to the ophthalmological apparatus ( 1 ).

Device and process for machining the human eye using laser technology

A device for machining the human cornea with focused laser radiation includes controllable components for setting the location of the radiation focus, a control computer for controlling these components, and also a control program for the control computer. The control program contains instructions that have been designed to bring about, upon execution by the control computer, the generation of incisions in the cornea in accordance with a predetermined incision figure, the incision figure defining a corneal bed, a flap situated on the bed and also at least one tissue strip situated in the region of the peripheral edge of the flap between the bed and the flap and extending along the edge of the flap. After the flap has been folded away, the tissue strip has to be removed and enables a creaseless post-ablative close fitting of the folded-back flap against the surface of the bed. In this manner, microstriae which may impair the visual capacity can be avoided.

Device and process for machining the cornea of a human eye with focused pulsed laser radiation

A device for machining the cornea of a human eye with focused pulsed laser radiation includes controllable components, a control computer for controlling these components and a control program for the control computer. The control program contains instructions that are designed to generate an incision figure in the cornea permitting the insertion of an intrastromal corneal ring implant. The incision figure includes a ring incision situated totally deep within the corneal tissue and an opening incision extending at right angles to the ring plane of the ring incision from the anterior surface of the cornea or from the posterior surface of the cornea as far as at least the ring incision. The ring incision exhibits, assigned to the opening incision ( 44 ), a radial—relative to the ring axis—widening zone in which the opening incision impinges on the ring incision.

Apparatus for assistance in the implantation of a corneal prosthesis in a human eye and method for executing such an implantation

Proposed is an apparatus for assistance in the implantation of a corneal prosthesis in a human eye. The apparatus comprises a laser device for providing focussed, pulsed laser radiation, and a control program for the laser device. The control program is designed, to create an incision figure in the tissue of the eye by means of the laser radiation, this incision figure allowing the corneal prosthesis to be inserted. The incision figure in this case comprises a bed incision located entirely in the depth of the corneal material and an annular incision, which, within the circumferential line of the bed incision, extends from the latter, along its entire annular circumference, as far as the corneal anterior surface. The incision figure further may comprise an auxiliary incision, which extends from a location of the eye surface outside the circumferential line of the bed incision as far the bed incision.

NONLINEAR OPTICAL PHOTODYNAMIC THERAPY (NLO-PDT) OF THE CORNEA

The embodiments include method of nonlinear optical photodynamic therapy of tissue including the steps of providing pulsed infrared laser light for two-photon excited fluorescence tissue exposure, and selectively focusing the pulsed infrared laser light within the tissue at a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. The invention is also directed to an apparatus for performing nonlinear optical photodynamic therapy of tissue including a pulsed infrared laser for providing two-photon excited fluorescence beam tissue exposure, a scanner for selectively and controllably moving the tissue and the beam relative to each other, and optics for selectively focusing the pulsed infrared laser light within the tissue at a point in a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. 1. A method of nonlinear optical photodynamic therapy of tissue comprising:providing a focal spot of a pulsed infrared laser light for multiphoton tissue exposure through a focusing lens, the focal spot having a volume and the focusing lens having an effective numerical aperture;selectively, repetitively and three dimensionally positioning the focal spot in the tissue in a selected volume of the tissue larger than the volume of the focal spot to expose the selected volume of tissue to the pulsed infrared laser light within a predetermined clinical time span; andwhere providing the focal spot provides the focal spot with a selected focal volume and predetermined safe intensity sufficient to activate a photosensitizing agent in the tissue in the volume of tissue to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue by utilizing the predetermined safe intensity of the focal spot and by adjusting the volume of the focal spot of the pulsed infrared laser light ...

Restoration of accommodation by lens refilling

A method for refilling a lens of an eye or increasing the elasticity of a lens of an eye includes removing a central portion of the lens core through the eye's cornea, a capsulorhexis in the eye's lens capsule and a gullet extending at least partially through the cortex of the lens. The lens is then refilled with a synthetic lens material. Sufficient lens core is left in place so that the synthetic material is not in contact with a lens capsule of the eye. The synthetic material used for refilling may be selected and may be formed in a shape and thickness so as to affect the refractive characteristics of the lens. An endocapsular lenticule may be inserted in the lens to affect the refractive characteristics of the lens.

Eye Therapy System

Heat is generated in corneal fibrils in a cornea of an eye according to a selected pattern. The heat causes the corneal fibrils corresponding to the selected pattern to transition from a first structure to a second structure. The second structure provides a desired reshaping of the cornea. A cross-linking agent is then activated in the region of corneal fibrils according to the selected pattern. The cross-linking agent prevents the corneal fibrils from changing from the second structure. Thus, embodiments stabilize corneal tissue and improve its biomechanical strength after desired structural changes have been achieved in the corneal tissue. Accordingly, the embodiments help to preserve the desired reshaping of the cornea.

Laser-Assisted Thermal Separation of Tissue

A laser-assisted method for fully or partially separating tissue such as collagen-containing tissue is provided. In one embodiment, the method pertains to a capsolurorhexis whereby the laser-assisted method is applied to the lens capsule. A light-absorbing agent is added into or onto the tissue. A light beam with a wavelength capable of being absorbed by the light absorbing agent is then directed at the tissue to cause a thermal effect at the tissue following a predetermined closed curve with the goal to avoid irregularity- or potential tears in the resulting rim of the tissue.

System and apparatus for delivering a laser beam to the lens of an eye

A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided a range determining system for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.

Methods and systems for performing a posterior capsulotomy and for laser eye surgery with a penetrated cornea

Method and apparatus for performing a laser-assisted posterior capsulotomy and for performing laser eye surgery on an eye having a penetrated cornea are provided. A method for performing a posterior capsulotomy includes injecting fluid between the lens posterior capsule and the anterior hyaloids membrane to separate the lens posterior capsule and the anterior hyaloids membrane. With the lens posterior capsule separated from the anterior hyaloids membrane, a posterior capsulotomy is performed on the lens posterior capsule by using a laser to incise the lens posterior capsule.

Ophthalmological device

An ophthalmological device ( 1 ) comprises an optical transmission system ( 5 ) for transmitting femtosecond laser pulses to a projection objective ( 3 ) for projecting the femto-second laser pulses onto or into eye ( 2 ) tissue. The ophthalmological device ( 1 ) further comprises an objective changing device ( 4 ) for changing and connecting the projection objective ( 3 ) to the optical transmission system ( 5 ). The objective changing device ( 4 ) comprises more than one different projection objectives ( 3 ) connected mechanically with each other, and the objective changing device ( 4 ) is configured to convey one of to the projection objectives ( 3 ) to the optical transmission system ( 5 ) for connecting the respective projection objective ( 3 ) to the optical transmission system ( 5 ). The objective changing device ( 4 ) makes it possible to adapt the laser-based ophthalmological device ( 1 ) for new applications without the need for extensive reconfigurations and/or costly vario-lense objectives.

Method and Systems for Laser Treatment of Presbyopia Using Offset Imaging

An ophthalmic surgery system and method for treating presbyopia by performing ablative photodecomposition of the corneal surface. The offset image of a variable aperture, such as a variable width slit and variable diameter iris diaphragm, is scanned in a preselected pattern to perform ablative sculpting of predetermined portions of a corneal surface. The scanning is performed to ablate an optical zone sized to match the patient pupil with a peripheral transition zone outside the pupil. The shape of the ablated optical zone is different from the shape of the final optical correction on the anterior surface of the cornea. The optical zone corrects for near-vision centrally and far-vision peripherally. A movable image displacement mechanism enables radial displacement and angular rotation of the profiled beam exiting from the variable aperture. The invention enables wide area treatment with a laser having a narrower beam than the treatment area, and can be used in the treatment of many conditions in conjunction with presbyopia such as hyperopia, hyperopic astigmatism and irregular refractive aberrations.

USE OF A TREATMENT DEVICE WITH A LASER FOR CORRECTING AN EYE TISSUE, AND A METHOD FOR PROVIDING CONTROL DATA FOR A LASER FOR CORRECTING AN EYE TISSUE

Use of a treatment apparatus is disclosed for cut-free transfer of a tissue of a correction area of a human or animal eye from a determined actual state into an ascertained desired state. The treatment apparatus includes a fiber laser device, which includes a fiber oscillator and/or a fiber amplifier. In addition, a method is disclosed for providing control data of a fiber laser device for a correction of the eye tissue as well as to the corresponding apparatuses. 115.-. (canceled)16. A treatment apparatus for a correction of an eye tissue comprising:at least one fiber laser device including a fiber oscillator and/or a fiber amplifier; and determine an actual state of a tissue of a correction area of a human or animal eye,', 'ascertain a desired state of the tissue based on the determined actual state of the tissue, and', 'provide control data to the at least one fiber laser device that describes an operation of the at least one fiber laser device for cut-free transfer of the tissue of the correction area from the determined actual state into the ascertained desired state., 'a control device configured to'}1715. The treatment apparatus according to claim , wherein the fiber laser device is suitable to emit laser pulses in a wavelength range between 300 nm and 1400 nm , preferably between 700 nm and 1200 nm , at a respective pulse duration between 1 fs and 1 ns , preferably between 10 fs and 10 ps , and a repetition frequency of greater than 10 kHz , preferably between 100 kHz and 100 MHz.18. The treatment apparatus according to claim 16 , wherein the control device comprisesat least one storage device for at least temporary storage of at least one control dataset, wherein the at least one control dataset includes control data for positioning and/or for focusing individual laser pulses in the cornea, andat least one beam device for beam guidance and/or beam shaping and/or beam deflection and/or beam focusing of a laser beam of the at least one fiber laser device.19. ...

MICRO-DEVICES FOR TREATMENT OF AN EYE

A micro-device for corneal cross-linking treatment includes a body including an outer portion and an inner portion. The outer portion is disposed about a periphery of the inner portion. The inner portion is shaped such that, when the body is positioned against a surface of an eye, the outer portion contacts the surface of the eye and the inner portion defines a chamber over a cornea of the eye. The micro-device includes an illumination system including a micro-optical element coupled to the body. The micro-optical element is configured to direct photoactivating light to the cornea of the eye when the body is positioned against the surface of the eye. The photoactivating light generates cross-linking activity with a cross-linking agent applied to the cornea. 1. A micro-device for corneal cross-linking treatment , comprising:a body including an outer portion and an inner portion, the outer portion being disposed about a periphery of the inner portion, the inner portion being shaped such that, when the body is positioned against a surface of an eye, the outer portion contacts the surface of the eye and the inner portion defines a chamber over a cornea of the eye; andan illumination system including a micro-optical element coupled to the body, the micro-optical element being configured to direct photoactivating light to the cornea of the eye when the body is positioned against the surface of the eye, the photoactivating light generating cross-linking activity with a cross-linking agent applied to the cornea.2. The micro-device of claim 1 , wherein the micro-optical element is coupled to the inner portion of the body and directs the photoactivating light through the chamber to the cornea of the eye.3. The micro-device of claim 1 , wherein the illumination system includes an optical fiber coupling the micro-optical element to a light source claim 1 , and the optical fiber includes an angled reflecting surface configured to reflect the photoactivating light from the light ...

COMPACT ULTRA-SHORT PULSED LASER EYE SURGERY WORKSTATION

A compact system for performing laser ophthalmic surgery is disclosed. An embodiment of the system includes a mode-locked fiber oscillator-based ultra-short pulsed laser capable of producing laser pulses in the range of 1 nJ to 5 μJ at a pulse repetition rate of between 5 MHz and 25 MHz, a resonant optical scanner oscillating at a frequency of 200 Hz and 21000 Hz, a scan-line rotator, a movable XY-san device, a z-scan device, and a controller configured to coordinate with the other components of the system to produce one or more desired incision patterns. The system also includes compact visualization optics for in-process monitoring using a beam-splitter inside the cone of a patient interface used to fixate the patient's eye during surgery. The system can be configured such that eye surgery is performed while the patient is either sitting upright, or lying on his or her back. 1. An ophthalmic surgical laser system comprising:a laser delivery system configured to deliver a pulsed laser beam at a focal point of a target in a patient's eye, the pulsed laser beam having a pulse repetition rate in the range between 5 MHz and 25 MHz;a resonant optical scanner, the scanner oscillating at a frequency between 200 Hz and 21000 Hz.an xy-scan device configured to move the pulsed laser beam in a lateral direction;a z-scan device configured to modify a depth of focus of the pulsed laser beam; anda controller operably coupled with the laser delivery system, the xy-scan device and the z-scan device, the controller configured to direct the laser delivery system to output the pulsed laser beam in a desired pattern at the focal point of the target in the eye so as to modify the target.228-. (canceled)29. An interface for coupling a patient's eye to an ophthalmic surgical laser system , the interface comprising: an apex ring coupled to the first plane surface, the apex ring comprising a distal end;', "a first receptacle configured to receive an attachment ring, the attachment ring ...

LASER-ASSISTED THERMAL SEPARATION OF TISSUE

A laser-assisted method for fully or partially separating tissue such as collagen containing tissue is provided. In one embodiment, the method pertains to a capsulorhexis whereby the laser-assisted method is applied to the lens capsule. A light-absorbing agent is added into or onto the tissue. A light beam with a wavelength capable of being absorbed by the light absorbing agent is then directed at the tissue to cause a thermal effect at the tissue following a predetermined closed curve with the goal to avoid irregularity or potential tears in the resulting rim of the tissue. 1. A device for thermally separating tissue in the anterior lens capsule of an eye in a procedure creating an opening in the anterior lens capsule , the device comprising:a laser device programmed to direct a laser beam along a predetermined closed curve on the anterior lens capsule;wherein the laser beam power, wavelength, and diameter at the anterior lens capsule are selected such that the laser beam is absorbed by a light absorbing agent in or on the anterior lens capsule to locally heat the anterior lens capsule along the closed curve without ablation of the anterior lens capsule, thereby separating the anterior lens capsule along the closed curve to form an area of anterior lens capsule tissue inside the closed curve and an area of anterior lens capsule tissue outside the closed curve, the lens capsule tissue outside the closed curve defining the boundary of the opening in the anterior lens capsule;wherein the laser device is programmed to direct the laser beam in a single pass starting at an initial point interior to the closed curve, then along the closed curve, and then to a final point interior to the closed curve;wherein the laser beam diameter at the anterior lens capsule is 50 microns to 600 microns;wherein the laser beam power at the anterior lens capsule is less than or equal to 1000 mW;wherein the laser beam is directed along the closed curve at less than or equal to 10 ...

SYSTEM AND METHOD FOR MANAGING PATIENT DATA DURING OPHTHALMIC SURGERY

The present disclosure provides a system and method for managing patient data during ophthalmic surgery. The systems and methods include an ophthalmic surgical device operable to receive data from a RFID chip. Data from the RFID chip is transmitted to a RFID read-write module operably coupled to the ophthalmic surgical system. A processor identifies the RFID chip based on the received data and determines whether the data stored to the RFID chip varies from data received from a surgical microscope by more than a predetermined percentage. The processor can generate a warning when the data stored to the RFID chip varies from data received from a surgical microscope by more than a predetermined percentage. 1. An ophthalmic surgical device comprising:a surgical microscope;a user interface;an RFID read-write module operable read an RFID chip and write patient data to an RFID chip associated with a patient;surgical instrumentation;a warning system; receive data from the RFID chip associated with a patient;', 'receive data from the surgical microscope associated with the patient;', 'compare the data from the RFID chip to the data from the surgical microscope;', 'determine whether the data from the RFID chip varies from the data from the surgical microscope by more than a predetermined percentage;', 'generate a warning, if the data from the RFID chip and the data from the surgical microscope vary by more than the predetermined percentage; and', 'transmit the warning to the warning system, causing the warning system to present a warning., 'and a processor operable to2. The ophthalmic surgical device of claim 1 , further comprising:an RFID chip associated with the ophthalmic surgical system.3. The ophthalmic surgical device of claim 1 , further comprising:a control device associated with the ophthalmic surgical system,wherein the RFID chip is connected to the ophthalmic surgical device, the RFID chip operable to transmit data to the processor, and wherein the processor is ...

CORNEAL DENERVATION FOR TREATMENT OF OCULAR PAIN

Methods and apparatus for the treatment of the eye to reduce pain can treat at least an outer region of the tissue so as to denervate nerves extending into the inner region and reduce the pain. For example, the cornea of the eye may comprise an inner region having an epithelial defect, and an outer portion of the cornea can be treated to reduce pain of the epithelial defect. The outer portion of the cornea can be treated to denervate nerves extending from the outer portion to the inner portion. The outer portion can be treated in many ways to denervate the nerve, for example with one or more of heat, cold or a denervating noxious substance such as capsaicin. The denervation of the nerve can be reversible, such that corneal innervation can return following treatment. 1. A method of treating a cornea of an eye , comprising:applying an apparatus to an anterior surface of a cornea, wherein the cornea comprises an epithelium, a stroma, an inner portion and an outer portion; andapplying energy from the apparatus to denervate a region of the cornea corresponding to a denervation treatment profile.2. The method of claim 1 , wherein treating comprises denervating a portion of the cornea.3. The method of claim 1 , wherein treating comprises denervating an inner portion of the cornea.4. The method of claim 1 , wherein the apparatus comprises an annular ring configured to contact the cornea.5. The method of claim 1 , wherein the energy comprises radiofrequency energy claim 1 , heating claim 1 , cooling claim 1 , light claim 1 , or ultrasound.6. The method of claim 1 , wherein applying energy comprises applying energy to the outer portion according to the denervation treatment profile.7. The method of claim 1 , wherein denervating comprises severing axons in the region of the cornea.8. The method of claim 1 , wherein denervation comprises stunning corneal nerves claim 1 , increasing the threshold of the corneal nerves claim 1 , inhibiting corneal nerve transmission claim 1 , ...

PATIENT INTERFACE FOR OPHTHALMOLOGIC DIAGNOSTIC AND INTERVENTIONAL PROCEDURES

An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device. 127.-. (canceled)28. A system for ophthalmic intervention on an eye of a patient having temporary geometric markers thereon indicative of the orientation of an astigmatic axis of the patient's eye , comprising:a. an imaging device having a field of view oriented toward the eye of the patient, the imaging device configured for generating 3-dimensional images of the field of view;b. a patient interface housing having proximal and distal ends and defining a passage therethrough, wherein the distal end is coupled to one or more seals around a periphery of the passage configured to be directly engaged with an exterior surface of the eye of the patient and having a size sufficient to render visible the temporary geometric markers on the eye in that the temporary geometric markers are within the field of view of the imaging device, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage;c. three or more registration fiducials formed on an inner annulus of the patient interface housing ...

LENTICULAR LASER INCISION FOR LOW MYOPIA AND/OR HYPEROPIA PATIENTS

Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incisions to form a top lenticular incision, a bottom lenticular incision of a lens in the subject's eye, an added shape between the top and bottom incisions where the added shape has no corrective power and a transition ring bisecting both the top and bottom lenticular incisions. 1. A method for creating lenticular incisions to correct low myopic/hyperopic patients using an ophthalmic surgical laser system , the method comprising:generating a pulsed femtosecond laser beam;delivering the pulsed femtosecond laser beam into a stroma of a cornea;deflecting, by an XY-scan device, the pulsed laser beam;modifying, by a Z-scan device, a depth of a focus of the pulsed laser beam; and a top lenticular incision in the stroma of the cornea, having a circumferential periphery;', 'a bottom lenticular incision in the stroma of the cornea, symmetric to the top lenticular incision, having a circumferential periphery;', 'a shape with no correction power to space the top lenticular incision and the bottom lenticular incision; and', 'a transition ring or side cut incision intersecting the circumferential periphery of the top lenticular incision and the circumferential periphery of the bottom lenticular incision., 'controlling, by a controller, the XY-scan device and the Z-scan device to form an incised lenticule in the cornea, by incising,'}2. The method of wherein the shape with no correction power is determined based on the amount of correction of hyperopia and/or myopia needed.3. The method of wherein the incised lenticule is at least 40 μm thick at its center.4. The method of wherein low hyperopic/myopic patients are 0.5 diopters to 3.0 diopters.5. The method of wherein the transition ring incision has a top edge and a bottom edge claim 1 , and the top edge and the bottom edge have the same circumference.6. The method of wherein the transition ring has a ...

CAPSULAR MEMBRANE IMPLANTS TO INCREASE ACCOMMODATIVE AMPLITUDE

A support is coupled to the lens capsule to increase accommodation. The support may be adjustable, such that patient refraction and accommodation can be adjusted following surgery. The support may comprise rigidity sufficient to decrease radial movement of the intermediate portion of the lens capsule. The support can be placed on the intermediate portion to decrease radial movement of the intermediate portion of the lens capsule and increase radial stretching of an outer portion of the lens capsule extending between the zonules and the intermediate portion coupled to the support, such that the amount of accommodation of the eye is increased. The support may comprise a biocompatible material capable of stable coupling to the lens capsule following implantation, such that the far vision refraction and accommodation of the eye can be stable following surgery. 1. A method of treating an eye , the eye having a lens and a capsule , the method comprising:placing a support on an intermediate portion of the capsule to decrease radial movement of the intermediate portion and increase an amount of accommodation of the eye.2. The method of claim 1 , wherein a peripheral portion of the lens capsule is coupled to the intermediate portion of the lens capsule and wherein radial movement of the peripheral portion is increased when the support is coupled to the intermediate portion.3. The method of claim 1 , wherein a central portion of the lens capsule is coupled to the peripheral portion and wherein an anterior movement of the central portion is increased when the intermediate portion is coupled to the support.4. The method of claim 1 , wherein the decreased radial movement comprises one or more of a stretching claim 1 , a bending claim 1 , a flexing claim 1 , a translation or a rotation of the intermediate portion.5. The method of claim 1 , wherein the eye has a first amount of accommodation prior to placement of the support on the eye and a second amount of accommodation when the ...

PREFORMED LENS SYSTEMS AND METHODS

Systems, methods, computer program products, and kits involving deformation mechanisms are provided for the removal of corneal tissue in optical vision treatments. According to exemplary embodiments, deformation mechanisms may be used in combination with the administration of femtosecond photoalteration lasers to create or define volumetric tissue portions for such removal. 1. A method of providing a surgical treatment to an eye of a patient , the method comprising:positioning a corneal deformation mechanism against an anterior surface of the eye of the patient, so as to induce a first intended biomechanical conformation within a corneal stromal tissue of the eye;delivering a first photoaltering energy protocol to the eye while the corneal stromal tissue is in the first intended biomechanical conformation, so as to incise the corneal stromal tissue along a first target surface;positioning the corneal deformation mechanism against the anterior surface of the eye of the patient, such that the corneal stromal tissue of the eye assumes a second intended biomechanical conformation different from the first intended biomechanical conformation;delivering a second photoaltering energy protocol to the eye while the corneal stromal tissue is in the second intended biomechanical conformation, so as to incise the corneal stromal tissue along a second target surface different from the first target surface; andremoving a portion of corneal stromal tissue bounded by the first and second target surfaces,wherein the corneal deformation mechanism comprises an applanation assembly that provides a first shape configuration and a second shape configuration, such that when in the first shape configuration, the applanation assembly is shaped to induce the first intended biomechanical conformation within the corneal stromal tissue, and when in the second shape configuration, the applanation assembly is shaped to induce the second intended biomechanical conformation within the corneal ...

SUB-NANOSECOND LASER SURGERY SYSTEM UTILIZING MULTIPLE PULSED LASER BEAMS

A system for laser ophthalmic surgery includes: a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam. The first treatment laser beam has a pulse energy of 10 to 500 μJ. The second pulsed laser beam has a second pulse energy of about 0.1 to 10 μJ, lower than the first treatment laser beam. An optical system focuses the first treatment laser beam to a first focal spot and directs the first focal spot in a first treatment pattern into a first intraocular target. The optical system also focuses the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into a second intraocular target. The first intraocular target and second intraocular target are different. 1. A system for laser ophthalmic surgery on an eye of a patient , comprising:a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam, each treatment laser beam comprising a plurality of laser pulses, the first treatment laser beam having a pulse energy of about 10 to 500 μJ and the second pulsed laser beam having a second pulse energy of about 0.1 to 10 μJ and lower than the first treatment laser beam; andan optical system operatively coupled to the laser source by the controller and configured to focus the first treatment laser beam to a first focal spot and direct the first focal spot in a first treatment pattern into one or more intraocular targets, including a first intraocular target,the optical system being further configured to focus the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into the one or more intraocular targets, including a second intraocular target,wherein the first intraocular target is different than the second intraocular target.2. The system of ...

SUB-NANOSECOND LASER CATARACT SURGERY SYSTEM

Systems and methods for fragmenting a lens by a laser cataract surgery system includes a sub-nanosecond laser source generating a treatment beam that includes a plurality of laser beam pulses. An optical delivery system is coupled to the sub-nanosecond laser source to receive and direct the treatment beam. A processor is coupled to the sub-nanosecond laser source and the optical delivery system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine a lens cut pattern for lens fragmentation and determine a plurality of energies of the treatment beam as a linear function of a depth of the lens cut pattern. The treatment beam is output according to the lens cut pattern and the determined energies. 1. A laser cataract surgery system , comprising:a sub-nanosecond laser source generating a treatment beam that includes a plurality of laser beam pulses;an optical delivery system coupled to the sub-nanosecond laser source to receive and direct the treatment beam; and,a processor coupled to the sub-nanosecond laser source and the optical delivery system, the processor comprising a tangible non-volatile computer readable medium comprising instructions to:determine a lens cut pattern for lens fragmentation;determine a plurality of energies of the treatment beam as a linear function of a depth of the lens cut pattern; andoutput the treatment beam according to the lens cut pattern and the determined energies.2. The laser cataract system of claim 1 , wherein the plurality of energies of the treatment beam are between twice an energy threshold and ten times an energy threshold.3. The laser cataract system of claim 2 , wherein the energy threshold is an energy level at which visible damage in tissue is first observed.4. The laser cataract system of claim 3 , wherein the sub-nanosecond laser source generates the treatment beam with an energy five times the energy threshold of the tissue.5. The laser cataract system of claim 1 , ...

MEDICAL TOOLS WITH ASPIRATION TIPS SUITABLE FOR CATARACT SURGERIES AND RELATED METHODS

Devices and methods for cataract surgery include a tip with reciprocating door to chop, fragment or reduce size of large nuclear lens fragments and/or cortex fragments in a capsule bag to facilitate aspiration. 1. A method of performing cataract surgery , comprising:performing a phacoemulsification or laser disintegration procedure on an eye of a patient;inserting, in vivo, a tip of an aspiration tool that is in fluid communication with an aspiration channel into a posterior capsule bag of a patient, wherein the tip comprises an open leading end that defines an aspiration port and one or both of (i) a longitudinally translatable door that is configured to retract and extend to at least partially cover the aspiration port or (ii) first and second cooperating members that form the leading end of the tip and allow the leading end of the tip to open from a first configuration with a first size of the aspiration port to a second configuration with a second larger size of the aspiration port;aspirating nuclear lens and/or cortex fragments into the aspiration channel using the aspiration port; andmanually and/or automatically directing (a) the door to reciprocate in a longitudinal direction over the aspiration port or (b) the tip to successively open from the first configuration to the second configuration to thereby reduce a size of at least one nuclear lens fragment and/or cortex fragment to inhibit one or more nuclear lens fragments and/or one or more cortex fragments from blocking the aspiration port and/or the aspiration channel.2. The method of claim 1 , wherein the tip has the door and the method is carried out to manually and/or automatically directing the door to reciprocate claim 1 , and wherein the door comprises at least one aspiration port that is smaller than the aspiration port defined by the open leading end claim 1 , the method comprising manually or automatically directing the door to reciprocate in a longitudinal direction to at least partially cover the ...

PATIENT INTERFACE FOR OPHTHALMOLOGIC DIAGNOSTIC AND INTERVENTIONAL PROCEDURES

A patient interface assembly for interfacing an ophthalmic intervention system with an eye of a patient includes a housing, an optical lens coupled to the housing, an eye engagement assembly coupled to the housing, the eye engagement assembly including an inner seal and an outer seal, and a tissue migration bolster structure positioned between the inner seal and outer seal and configured to apply a resisting load against portions of the eye in a vacuum zone which are capable of distending upon application of the vacuum load. The eye engagement assembly is adapted to be placed into contact with the eye of the patient by sealably engaging the eye with the inner and outer seals, thereby defining the vacuum zone as being between the inner and outer seals when placed into contact with the eye. 121-. (canceled)22. A patient interface assembly for interfacing an ophthalmic intervention system with an eye of a patient , comprising:a housing;an optical lens coupled to the housing;an eye engagement assembly coupled to the housing, the eye engagement assembly comprising an inner seal and an outer seal, the eye engagement assembly adapted to be placed into contact with the eye of the patient by sealably engaging the eye with the inner and outer seals, thereby defining a vacuum zone between the inner and outer seals when placed into contact with the eye; anda tissue migration bolster structure positioned between the inner seal and outer seal and configured to apply a resisting load against portions of the eye in the vacuum zone which are capable of distending upon application of a vacuum load.231. The patient interface assembly of claim , further comprising means for monitoring one or more interfacial loads representative of contact loads applied to the eye of the patient by the patient interface assembly.241. The patient interface assembly of claim , further comprising one or more load cells operatively coupled to the patient interface configured to output a signal based upon ...

Calibration process for femtosecond laser intraocular lens modification system using video and oct targeting

The XYZ beam position of an ophthalmic laser system is calibrated by measuring a fluorescent signal induced by the focused laser beam in a thin glass coverslip via multiphoton absorption. A video camera measures the XY position and intensity of the fluorescent signal as the focused laser beam strikes the coverslip. The Z position of the focus is determined by scanning the targeted z position and identifying the Z scanner position of peak fluorescence. An OCT system measures the real space Z location of the coverslip, which is correlated with the Z scanner position. Other laser system parameters are assessed by repeatedly scanning a lower energy laser beam in a piece of IOL material, and observing damage (scattering voids) formation in the IOL material. Based on the rate of damage formation, laser system parameters such as beam quality, numerical aperture, pulse energy, and pulse duration, etc. can be assessed.

IMAGING SURGICAL TARGET TISSUE BY NONLINEAR SCANNING

Systems and techniques for laser surgery are described. Scan data may be created by determining a coordinate of the object at a set of points along an arc by the imaging system, wherein the coordinate of the object is a Z coordinate of an object layer. An object shape parameter and position parameter may be determined based on the scan data by a system control module by extracting an amplitude and a phase of the scan data determining a center of the object layer based on the extracted amplitude and phase. 1. A method for imaging an object , the method comprising the steps of:generating scan data by determining a coordinate of the object at a set of points along an arc by an imaging system, wherein the coordinate of the object is a Z coordinate of an object layer; and extracting an amplitude and a phase of the scan data; and', 'determining a center of the object layer based on the extracted amplitude and phase., 'determining an object shape parameter and an object position parameter based on the scan data by a system control module by'}2. The method of claim 1 , wherein:the object is a portion of a spherical surface layer; andthe determined object shape parameter is a radius of the spherical surface layer.3. The method of claim 1 , wherein:the object is an anterior lens surface layer of an eye;the object shape parameter is a radius of the anterior lens surface layer; andthe object position parameter is a coordinate of a center of the anterior lens surface.4. The method of claim 1 , wherein the determining the object position parameter step comprises:imaging the object with at least one of an optical coherence tomography (OCT) method, an ultrasound-based method, a microscopic method and an interference based method.5. The method of claim 1 , wherein the determining the object shape parameter and object position parameter step comprises:creating auxiliary scan data by determining a coordinate of the object at an auxiliary set of points along an auxiliary arc.6. The ...

Ophthalmological apparatus for the breakdown of eye tissue

An ophthalmological apparatus includes a handle for manually holding and applying the ophthalmological apparatus, fastening abilities for fixing the ophthalmological apparatus at an eye, a light source, and a light projector for the focused projection of light pulses for punctiform tissue breakdown at a focal point in the interior of the eye tissue. The ophthalmological apparatus also includes a movement driver for moving the light projector. The movement of the light projector and therefore that of the focal point with the assistance of the movement driver permits a dimensioning of the optical projection system of the light projector which is substantially smaller than in the case of an ophthalmological apparatus where the focal point is moved exclusively by an optical projection system.

LASER ASSISTED CATARACT SURGERY

Laser assisted cataract surgery methods and devices utilize one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may be applied to the anterior lens capsule to facilitate laser thermal separation of tissue along a treatment beam path on the lens capsule. Relative or absolute reflectance from the eye, and optionally from a surgical contact lens, may be measured to confirm and optionally quantify the presence of the light absorbing agent, before the treatment beam is applied. Such measurements may be used to determine that sufficient light absorbing agent is present in the lens capsule so that transmission of the treatment beam through the capsule will be below a predetermined threshold deemed safe for the retina and other interior portions of the eye, and may also be used to determine that sufficient light absorbing agent is present to result in complete laser thermal separation of the anterior capsule along the treatment beam path. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the capsulorrhexis procedure. In addition or alternatively, virtual visualization patterns may presented on a display integrated with a laser assisted cataract surgery device to aid in the procedure. The visual axis of the eye may be determined, during surgery for example, with a laser beam on which the patient is fixated. The orientation of a toric IOL may be assessed during or after placement by observing the reflection from the back of the eye of a laser beam on which the patient is fixated. The devices disclosed herein may be attached to or integrated with microscopes. 1. A device for creating an opening in the anterior lens capsule of the eye , the device comprising:a visible light laser beam blinking at a frequency perceptible to a human patient, directed into the eye, and establishing the visual ...

Anti-Astigmatic Keratotomy

The invention relates to an ophthalmological instrument for carrying out a laser-surgical intervention on the eye (), comprising a femtosecond laser (), which emits pulsed laser radiation (), an objective (), from which the laser radiation () emerges in a focused manner in the direction of the eye (), at least one deflection device (), which deflects the laser radiation () and which varies the focal position within the cornea () of the eye (), and a program-controlled control device (), which is connected to the deflection device () and configured to generate a predetermined cut profile within the cornea (), wherein the cut profile comprises at least one arcuate incision () in the periphery of the cornea (). It is an object of the invention to provide an improved ophthalmological instrument for anti-astigmatic keratotomy with the femtosecond laser (). This object is achieved by the invention by virtue of the program-controlled control device () being furthermore configured to vary the cut depth (D) along the arcuate incision (), the cut depth (D) reducing toward the ends of the arc. Moreover, the invention relates to a computer program for controlling an ophthalmological instrument. 141232462548659589. An ophthalmological instrument for carrying out a laser-surgical intervention on the eye () , comprising a femtosecond laser () , which emits pulsed laser radiation () , an objective () , from which the laser radiation () emerges in a focused manner in the direction of the eye () , at least one deflection device () , which deflects the laser radiation () and which varies the focal position within the cornea () of the eye () , and a program-controlled control device () , which is connected to the deflection device () and configured to generate a predetermined cut profile within the cornea () , wherein the cut profile comprises at least one arcuate incision () in the periphery of the cornea () , wherein the program-controlled device () is furthermore configured to vary ...

APPARATUS AND METHOD FOR CREATING INCISIONS IN A HUMAN CORNEA

An apparatus for creating incisions in a human cornea comprises: a source of pulsed laser radiation; a scanner device for scanning the laser radiation; and a control computer for controlling the scanner device based on a control program, the control program containing instructions that, when executed by the computer, bring about the creation in the cornea of: a flap cut defining a corneal flap that is connected to surrounding corneal tissue through a hinge; and one or more auxiliary cuts in connection with the flap cut for removing gas generated during creation of the flap cut, the one or more auxiliary cuts defining a first channel extending from the flap cut to an anterior surface of the cornea and a reservoir located at least partially deeper within the cornea than the flap cut. 1. An apparatus for creating incisions in a human cornea , the apparatus comprising:a source of pulsed laser radiation;a scanner device for scanning the laser radiation; a flap cut defining a corneal flap that is connected to surrounding corneal tissue through a hinge; and', 'one or more auxiliary cuts in connection with the flap cut for removing gas generated during creation of the flap cut, the one or more auxiliary cuts defining a first channel extending from the flap cut to an anterior surface of the cornea and a reservoir located at least partially deeper within the cornea than the flap cut., 'a control computer for controlling the scanner device based on a control program, the control program containing instructions that, when executed by the computer, bring about the creation in the cornea of2. The apparatus of claim 1 , wherein the reservoir is connected with the first channel.3. The apparatus of claim 1 , wherein locations of connection of the reservoir and the first channel with the flap cut are at least partially overlapping.4. The apparatus of claim 1 , wherein the reservoir and the first channel are each connected with the flap cut in a hinge area of the flap.5. The apparatus ...

CREATION OF CURVED CUTS IN THE INSIDE OF THE EYE CORNEA

A device for isolating a lenticle in the cornea of an eye. The device includes: a laser beam source to emit pulsed laser radiation having a pulse frequency of 1.2 MHz to 10 MHz, a pulse energy of 1 nJ to 200 nJ and a wavelength penetrating the cornea; a beam-forming unit having beam optics with an image field and that bundles pulsed laser radiation into a focus located inside the image field, and which has a maximum diameter of less than 3 μm; a beam-deflection unit shifting the focus in the cornea and inside the image field, the focus moving along a path when the image field is resting; and a control unit to control the source and the beam-forming unit to isolate the lenticle by specifying the path. The lenticle is delimited by a cut surface which is curved with regard to a front surface of the cornea. 1. A device for generating a cut in the interior of an eye , the device comprising:a laser beam source that is designed to emit a raw train of laser radiation pulses having a raw pulse frequency of at least 1.2 MHz and a wavelength which penetrates a cornea of the eye, wherein each laser radiation pulse of the raw train is adapted to separate layers of material within the eye;a pulse picker which selects some laser radiation pulses of the raw train to provide a modified train of laser radiation pulses adapted to separate layers of material within the eye, the modified train having a pulse frequency reduced over the raw pulse frequency;beam optics which bundle the laser radiation pulses into a focus located in the eye, anda beam scanner which shifts the focus in the eye along a path to generate the cut by the modified train of laser radiation pulses emitted while the focus is shifted along the path; anda processor, which is connected with the beam scanner and the pulse picker and is designed to control the beam scanner by specifying the path and thus defining location and extension of the cut.2. The device according to claim 1 , wherein the raw pulse frequency is not ...

RETINAL IMAGING FOR REFERENCE DURING LASER EYE SURGERY

A method of laser eye surgery including linking retinal vessel architecture to corneal topography. This enables registration of the steep axis of the cornea in order to orient a toric intraocular lens, and/or to place astigmatic keratotomy incisions. First, a detailed pre-operative retinal image of the vasculature of the retina is obtained. In addition, a pre-operative image of the topography of the eye is obtained. The retinal image is then correlated or superimposed on the topography image to provide a reference. After the patient lies down under the laser eye surgery system, and during the surgery, the retinal vasculature is monitored which provides a reference to the surgery system about the topography of the eye. This process enables registration of the steep axis of the cornea in order to orient a toric intraocular lens and/or to place astigmatic keratotomy incisions. 1. A method of eye surgery on an astigmatic patient , comprising:pre-operatively obtaining a first retinal image of the retinal vessel architecture or optic nerve;pre-operatively scanning the corneal topography of the patient to obtain a scan;correlating the first retinal image and scan to determine retinal landmarks associated with an astigmatic axis of the patient;recording the location of the retinal landmarks in an optical system of an eye surgery system used for the eye surgery;positioning the patient supine on a chair configured for the eye surgery;obtaining a second retinal image of the retinal vessel architecture or optic nerve while the patient is positioned on the chair;analyzing the second retinal image to gauge a misalignment of the eye compared to the first retinal image;adjusting the patient or eye surgery system based on the misalignment and correlation of the first and second retinal images and scan; andperforming an eye surgery.2. The method of claim 1 , wherein the eye surgery is insertion of a toric intraocular lens claim 1 , and the step of recording includes placing a reticle ...

METHODS OF LASER MODIFICATION OF INTRAOCULAR LENS

A method of modifying a refractive profile of an eye having an intraocular device implanted therein, wherein the method includes determining a corrected refractive profile for the eye based on an initial refractive profile, identifying one or more locations within the intraocular device based on the corrected refractive profile, and directing a pulsed laser beam at the locations to produce the corrected refractive profile. A system of modifying an intraocular device located within an eye, wherein the system includes a laser assembly and a controller coupled thereto. The laser assembly outputs a pulsed laser beam having a pulse width between 300 picoseconds and 10 femtoseconds. The controller directs the laser assembly to output the pulsed laser beam into the intraocular device. One or more slip zones are formed within the intraocular device in response thereto, and the slip zones are configured to modify a refractive profile of the intraocular device. 1. A method of modifying a refractive profile of an eye , the eye having an intraocular device implanted therein located at an initial position within the eye and the eye having an initial refractive profile , the method comprising the steps of:determining a corrected refractive profile for the eye based on the initial refractive profile;identifying one or more locations within the intraocular device based on the corrected refractive profile; anddirecting a pulsed laser beam at the one or more locations to re-orient the intraocular device to a corrected position within the eye and produce the corrected refractive profile.2. The method of claim 1 , wherein the intraocular device is re-oriented in response to the directed pulsed laser beam by at least one of the group consisting of a horizontal displacement claim 1 , a vertical displacement claim 1 , a rotation claim 1 , a tilt claim 1 , a displacement towards a cornea of the eye claim 1 , and a displacement toward a retina of the eye.3. The method of claim 1 , wherein ...

Machine-readable medium, keratotomy system, and keratotomy method

A corneal ablation system for correcting vision by using a laser is provided. The corneal ablation system includes: an operation device for creating an integrated corneal ablation plan for correcting a shape and a curvature error of a cornea based on corneal status data; a laser control unit for controlling a laser module according to an ablation position and an ablation shape of the cornea based on the integrated corneal ablation plan transmitted from the operation device; and the laser module for generating a laser and transmitting the laser to an optical unit under control of the laser control unit.

Device for Ophthalmic Surgery and Method of Use Therefor

A lens device for use in Selective Laser Trabeculoplasty (SLT) procedures is provided. The lens device includes four internal reflectors, each having a reflector surface configured to direct a laser beam pulse toward the trabecular meshwork region of a patient's eye. Each of the four internal reflectors is arranged to correspond to a particular quadrant of the patient's eye to enable the entire 360-degrees of the trabecular meshwork to be treated with laser pulses without rotation of the lens device. A method for performing an SLT procedure using the lens device is also provided. The method includes placing the lens device on the patient's eye, aligning the internal reflectors with the quadrants of the patient's eye, and directing laser pulses through each internal reflector until the trabecular meshwork in each quadrant of the patient's eye has been treated.

OPHTHALMIC TREATMENT DEVICE, SYSTEM, AND METHOD OF USE

Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye). The at least one treatment light promotes corneal and/or scleral collagen cross-linking. 1. An ophthalmic treatment system , comprising:a light source device comprising at least one light source;at least one optical treatment head operatively coupled to the light source device, and configured to provide at least one treatment light;at least one processor associated with the light source device and programmed to control operation of the light source device to provide a discontinuous treatment light projection onto a patient's eye for a selected treatment time comprising successive treatment light exposure periods of a first light intensity level separated by non-treatment periods at a second light intensity level lower than the first light intensity level; andwherein the at least one optical treatment head projects the treatment light at least two inches to the patient's eye such that a position of the at least one optical treatment head relative to the patient's eye allows physician visualization and accessibility to the patient's eye during treatment.2. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the treatment light at least three inches to the patient's eye.3. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the ...

OPHTHALMIC TREATMENT DEVICE, SYSTEM, AND METHOD OF USE

Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye). The at least one treatment light promotes corneal and/or scleral collagen cross-linking. 1. An ophthalmic treatment system , comprising:a light source device comprising at least one light source;at least one optical treatment head operatively coupled to the light source device, and configured to provide at least one treatment light;at least one processor associated with the light source device and programmed to control operation of the light source device to provide a discontinuous treatment light projection onto a patient's eye for a selected treatment time comprising successive treatment light exposure periods of a first light intensity level separated by non-treatment periods at a second light intensity level lower than the first light intensity level; andwherein each treatment light exposure period and non-treatment period of the discontinuous treatment light projection is in the range from 5 seconds to 25 seconds.2. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the treatment light at least two inches to the patient's eye.3. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the treatment light between three to six inches to the patient's eye.4. The ophthalmic treatment system of claim 1 , wherein the treatment light ...

Laser capsulovitreotomy

Methods and systems for performing laser-assisted surgery on an eye form a layer of bubbles in the Berger's space of the eye to increase separation between the posterior portion of the lens capsule of the eye and the anterior hyaloid surface of the eye. A laser is used to form the layer of bubbles in the Berger's space. The increased separation between the posterior portion of the lens capsule and the anterior hyaloid surface can be used to facilitate subsequent incision of the posterior portion of the lens capsule with decreased risk of compromising the anterior hyaloid surface. For example, the layer of bubbles can be formed prior to performing a capsulotomy on the posterior portion of the lens capsule.

CONTACT LENS FOR CORRECTIVE CORNEAL CROSSLINKING AND METHOD FOR PRODUCING SAME

A contact lens for corrective corneal crosslinking has a lens part and reservoir part. The lens part is constituted of a UV transmitting material, and provided, on a side thereof being in contact with the cornea of a patient's eyeball, with a pressing region configured to project in a convexly curved shape at a position for pressing the corneal dome center, and a relief region including an annular concave part whose cross section has a concavely circular arc shape that surrounds the pressing region's outer circumference. The reservoir part is disposed seamlessly and integrally therewith on the lens' outer side in a thickness direction in the pressing region, the reservoir part is provided with a communication hole for communication between the inside of the reservoir part and the pressing region, and a working electrode that has the same polarity as that of the riboflavin solution in the reservoir part. 1. A contact lens for corrective corneal crosslinking , the contact lens being constituted of a UV transmitting material , the contact lens having a relief region including a concave part and a pressing region including a convex part that are formed on a side of the contact lens in contact with a cornea of a patient , the contact lens being for correcting at least one of a naked eye vision and keratoconus cornea by pressing the relief region and the pressing region to the cornea to change a shape of the cornea , the contact lens for corrective corneal crosslinking comprising a lens part and a reservoir part , wherein:the lens part has, on the side thereof being in contact with the cornea of the patient, a circular central lens region that is located at a position being in contact with a corneal dome center when the contact lens is mounted on the cornea, and a ring-shaped region in a circular-ring shape surrounding the central lens region; one of the central lens region and the ring-shaped region constitutes the pressing region or the relief region and the other ...

CORNEAL VISUAL CENTER LOCALIZER (OR LOCATOR)

Daifs Corneal Visual Center (CVC) Localizer (Locator) is a point Light Source of Infra Red (IR) light, attached and fixed to any eximer laser machine, located at equal distance and in exactly opposite direction from the middle of a detecting camera that detects IR light reflection from the corneal surface and the pupillary margin of the iris with a point fixation target or its virtual extension, perpendicular to the plan containing the localizer and the middle point the inlet of the detecting camera, exactly in the middle of the distance between the localizing point light source and the middle point the detecting camera. With the Localizer in position and activated, the CVC will be seen on the screen of IR eye tracking as a white dot somewhere inside the white circle that represents the detected pupillary margin. The center of the pupil is automatically detected by the eye tracking software system and is marked on the screen by a cross which will considered by treatment software of the machine as the center of the refraction correction laser treatment. After accurate in-focus positioning of eye to be treated with the patient fixing the fixation target, the position of this cross could be manually changed to the position of the white dot representing the CVC and confirming by OK button. The relation between the CVC and the pupillary margin image is automatically fixed by the eye tracking system all over the whole laser treatment of this particular eye. 1. The nomenclature: Corneal Visual Center Localizer or CVC Localizer or Locator.2. A real or virtual (image or reflected or refracted) point Light Source of Infra Red (IR) , visible or other invisible light attached and fixed any eximer laser machine or any ophthalmic diagnostic or therapeutic machine or device (or any similar device) located at equal distance and in exactly opposite direction from the middle of a detecting appropriate camera (that can detect its invisible or visible light reflection from the corneal ...

METHODS AND SYSTEMS FOR LASER SCAN LOCATION VERIFICATION AND LASER SURGICAL SYSTEMS WITH LASER SCAN LOCATION VERIFICATION

A method of verifying a laser scan at a predetermined location within an object includes imaging at least a portion of the object, the resulting image comprising the predetermined location; identifying the predetermined location in the image, thereby establishing an expected scan location of the laser scan in the image; performing a laser scan on the object by scanning a focal point of the laser beam in a scanned area; detecting a luminescence from the scanned area and identifying an actual scanned location within the image based on the detected luminescence; and determining whether the difference between the actual scanned location and the expected scan location is within a threshold value. 1. A method of verifying the placement a laser scan at a predetermined location within an object , comprising:imaging at least a portion of the object, the resulting image comprising the predetermined location;identifying the predetermined location in the image, thereby establishing an expected scan location of the laser scan in the image;performing the laser scan on the object by scanning a focal point of a laser beam in a scanned area;detecting a luminescence from the scanned area and identifying an actual scanned location within the image based on the detected luminescence; andverifying whether the laser scan was at the predetermined location based on a difference between the actual scanned location and expected scan location.2. The method of claim 1 , wherein the object is a human eye.3. The method of claim 1 , wherein the object is a calibration apparatus.4. The method of claim 1 , wherein the laser beam is a pulsed laser beam having a wavelength of 320 nm to 370 nm.5. The method of claim 1 , wherein the luminescence has a wavelength of 400 nm or more.6. The method of claim 1 , wherein the image comprises an array of pixels.7. The method of claim 6 , wherein the expected location comprises one or more pixels selected from amongst the array of pixels.8. The method of claim 6 ...

METHODS AND SYSTEMS FOR CHANGING A REFRACTIVE PROPERTY OF AN IMPLANTABLE INTRAOCULAR LENS

A method of altering a refractive property of a crosslinked acrylic polymer material by irradiating the material with a high energy pulsed laser beam to change its refractive index. The method is used to alter the refractive property, and hence the optical power, of an implantable intraocular lens after implantation in the patient's eye. In some examples, the wavelength of the laser beam is in the far red and near IR range and the light is absorbed by the crosslinked acrylic polymer via two-photon absorption at high laser pulse energy. The method also includes designing laser beam scan patterns that compensate for effects of multiphone absorption such as a shift in the depth of the laser pulse absorption location, and compensate for effects caused by high laser pulse energy such as thermal lensing. The method can be used to form a Fresnel lens in the optical zone. 14.-. (canceled)5. A method of altering a refractive property of an implantable intraocular lens having an optic body including an optical zone and a peripheral zone surrounding the optical zone , comprising:implanting the intraocular lens in a patient's eye;generating a light beam using a light source and a light delivery optical system, the light beam having a wavelength of 400 to 450 nm; andwhile the intraocular lens is in the patient's eye, irradiating the optical zone of the intraocular lens with the light beam,wherein the optical zone comprises a crosslinked acrylic polymer material configured to change its refractive index upon irradiation by the light beam, thereby altering a refractive property of the intraocular lens.6. (canceled)7. The method of claim 5 , wherein a first change in the refractive index is negative during a first time period after irradiation and a second change in the refractive index is positive in a second time period after irradiation.8. The method of claim 5 , wherein the change in refractive index relative to the pre-irradiation refractive index at a location within the ...

VARYING A NUMERICAL APERTURE OF A LASER DURING LENS FRAGMENTATION IN CATARACT SURGERY

Some embodiments disclosed here provide for a method fragmenting a cataractous lens of a patient's eye using an ultra-short pulsed laser. The method can include determining, within a lens of a patient's eye, a high NA zone where a cone angle of a laser beam with a high numerical aperture is not shadowed by the iris, and a low NA zone radially closer to the iris where the cone angle of the laser beam with a low numerical aperture is not shadowed by the iris. Laser lens fragmentation is accomplished by delivering the laser beam with the high numerical aperture to the high NA zone, and the laser beam with the low numerical aperture to the low NA zone. This can result in a more effective fragmentation of a nucleus of the lens without exposing the retina to radiation above safety standards. 18.-. (canceled)9. A laser eye surgery control system comprising:a controller comprising one or more physical processors; ["a first region of a lens of a patient's eye to receive a laser beam having a first numerical aperture; and", "a second region of the lens of the patient's eye to receive a laser beam having a second numerical aperture, the second numerical aperture being lower than the first numerical aperture, and wherein at any given depth within a depth range along a central axis of the patient's eye, the second region is radially closer, on average, to an iris of the patient's eye than the first region; and"], 'a fragmentation module configured to use the one or more physical processors to determine a laser lens fragmentation treatment plan by determining control the laser source to deliver the laser beam having the first numerical aperture and a first energy to the first region of the lens without delivering the laser beam having the first numerical aperture and the first energy to the second region of the lens; and', "control the laser source to deliver the laser beam having the second numerical aperture and a second energy to the second region of the lens, wherein at any ...

VISUALIZATION AND TREATMENT OF MEDIA OPACITY IN EYE

A system for treating a media opacity in a vitreous media of an eye includes a visualization module adapted to provide visualization data of a portion of the eye via one or more viewing beams. The system includes a laser module adapted to selectively generate a treatment beam directed towards the media opacity in order to disrupt the media opacity. The laser module and the visualization module have a shared aperture for guiding the treatment beam and the one or more viewing beams towards the eye, the shared aperture being centered about a central axis. A controller is configured to acquire one or more defining parameters of the media opacity and determine when the media opacity is with a predefined target zone of a real-time viewing window. The media opacity is treated with the treatment beam when the media opacity is within the predefined target zone. 1. A system for treating a media opacity in a vitreous media of an eye , the system comprising:a visualization module adapted to provide visualization data of a portion of the eye via one or more viewing beams;a laser module adapted to selectively generate a treatment beam directed towards the media opacity in order to disrupt the media opacity; andwherein the laser module and the visualization module have a shared aperture for guiding the treatment beam and the one or more viewing beams towards the eye, the shared aperture being centered about a central axis.2. The system of claim 1 , further comprising:a controller in communication with the visualization module and the laser module, the controller having a processor and a tangible, non-transitory memory on which instructions are recorded; andwherein execution of the instructions by the processor causes the controller to acquire one or more defining parameters of the media opacity based at least partially on the visualization data, the one or more defining parameters including a shape and a size of the media opacity.3. The system of claim 2 , wherein the controller ...

SYSTEMS AND METHODS FOR EYE CATARACT REMOVAL

Systems and methods for assisting in the removal of a cataract from an eye can include obtaining pre-operative data for the eye, the pre-operative data including imaging data associated with the lens of the eye, determining a lens density map based on the imaging data associated with the lens, and generating laser fragmentation patterns for a laser fragmentation procedure based on the lens density map. 1. A method for use in relation to removing a lens of an eye , comprising:obtaining pre-operative data for the eye, the pre-operative data including imaging data associated with the lens of the eye;determining a lens density map based on the imaging data associated with the lens; andgenerating laser fragmentation patterns for a laser fragmentation procedure based on the lens density map.2. The method of claim 1 , determining the lens density map comprises analyzing an intensity of each of a plurality of pixels or each of a plurality of voxels from the imaging data.3. The method of claim 1 , further comprising determining a type of cataract based on the lens density map claim 1 , wherein generating the laser fragmentation patterns is further based on the type of cataract.4. The method of claim 1 , further comprising generating one or more device settings for a laser device used for performing the laser fragmentation procedure.5. The method of claim 4 , wherein the one or more device settings comprise a frequency of laser claim 4 , a power of laser claim 4 , a speed of laser claim 4 , or a type of laser.6. The method of claim 1 , wherein the generated laser fragmentation patters indicate at least one of a position and orientation of fragmentation lines claim 1 , a distance between the fragmentation lines claim 1 , a separation distance between laser treatment spots along the fragmentation lines claim 1 , a use of curved lines claim 1 , a use of spiral or irregular patterns claim 1 , a depth of cuts along each of the fragmentation lines claim 1 , or an angle of incidence ...

METHOD AND SYSTEM FOR IMPROVING VISION OF AN EYE WITH MACULAR DEGENERATION

Methods and apparatus are disclosed for diagnosing vision and improving vision, for example by reducing or eliminating the effects of macular degeneration, in a manner which does not interfere with the natural shape of the cornea or its orientation relative to the remainder of the eye, but which changes its surface curvature appropriately to achieve the required correction of vision. The focus of sub-regions of the cornea is adjusted so that different regions focus at a controlled distance about a reference axis. This can be accomplished by shaping the cornea (e.g. through ablation) or by applying an appropriate contact lens or other optical lens.

APPARATUS FOR WORKING ON EYE TISSUE BY MEANS OF A PULSED LASER BEAM

For the purposes of working on eye tissue, an ophthalmological apparatus comprises a laser source that is configured to produce a pulsed laser beam, a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue, and a scanner system for deflecting the pulsed laser beam onto work target points in the eye tissue. A circuit controls the scanner system in such a way that the scanner system guides the pulsed laser beam into work trajectories that extend next to one another, in order, initially, to produce cut trajectories, separated by remaining tissue bridges, of a tissue cut to be undertaken in an area and in order, thereafter, to guide the pulsed laser beam in the remaining tissue bridges between the cut trajectories in order to complete the tissue cut. 1. Ophthalmological apparatus for working on eye tissue , comprising a laser source that is configured to produce a pulsed laser beam; a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue; a scanner system that is configured to guide the pulsed laser beam onto work target points in the eye tissue; and a circuit that is configured to control the scanner system in such a way that the scanner system guides the pulsed laser beam onto work target points in an area to be cut in a cornea , in work trajectories that extend next to one another , in order , initially , to produce cut trajectories , separated by remaining tissue bridges , of a tissue cut to be undertaken in the area and in order , thereafter , to guide the pulsed laser beam onto work target points in the remaining tissue bridges between the cut trajectories in the area in order to complete the tissue cut , wherein the ophthalmological apparatus comprises a measurement system that is configured to optically capture structures in the eye tissue; and the circuit is configured to control the measurement system in such a way that the measurement system captures the produced cut trajectories and ...

APPARATUS FOR WORKING ON EYE TISSUE BY MEANS OF A PULSED LASER BEAM

For the purposes of working on eye tissue, an ophthalmological apparatus comprises a laser source that is configured to produce a pulsed laser beam, a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue, a scanner system for deflecting the pulsed laser beam onto work target points in the eye tissue, and a measurement system for optically capturing structures in the eye tissue. A circuit controls the measurement system in such a way that the latter captures a cut first outer face of a lenticule to be cut. The circuit controls the scanner system in such a way that the latter guides the pulsed laser beam onto work target points on a second outer face, positioned in relation to the captured first outer face, of the lenticule to be cut, in order to cut the second outer face of the lenticule. 1. Ophthalmological apparatus for working on eye tissue , comprising a laser source that is configured to produce a pulsed laser beam; a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue; a scanner system that is configured to guide the pulsed laser beam onto work target points in the eye tissue; a measurement system that is configured to optically capture structures in the eye tissue; and a circuit that is configured to control the scanner system in such a way that the scanner system guides the pulsed laser beam onto work target points on a first outer face of a lenticule to be cut in the eye tissue in order to produce a first tissue cut for cutting the lenticule;where the circuit is further configured to control the measurement system in such a way that the measurement system captures the first outer face of the lenticule that is produced by the first tissue cut and to control the scanner system in such a way that the scanner system guides the pulsed laser beam onto work target points on a second outer face, positioned in relation to the captured first outer face of the lenticule to be cut in order to ...

OPHTHALMIC LASER DELIVERY APPARATUS USING MEMS MICROMIRROR ARRAYS FOR SCANNING AND FOCUSING LASER BEAM

In a laser delivery system for an ophthalmic laser surgery system, a laser beam scanner employs a single or two MEMS micromirror arrays. Each micromirror in the array is capable of being independently actuated to rotate to desired angles. In one embodiment, one or two micromirror arrays are controlled to scan a laser beam in two directions. In another embodiment, a micromirror array is controlled to both correct optical aberrations in the laser beam and scan the laser beam in two directions. In yet another embodiment, a micromirror array is controlled to cause the laser beam to be focused to multiple focal spots simultaneously and to scan the multiple focal spot simultaneously. The ophthalmic laser surgery system also includes an ultrashort pulse laser, a laser energy control module, focusing optics and other optics, and a controller for controlling the laser beam scanner and other components of the system. 17-. (canceled)8. An ophthalmic laser delivery method for delivering a pulsed laser beam generated by a laser to a patient's eye , comprising:directing the pulsed laser beam from the laser to a laser beam scanner, the laser beam scanner including at least one micromirror array, the micromirror array including a plurality of micromirrors forming a two-dimensional array, the plurality of micromirrors capable of being individually controlled to rotate to different angles;using a controller coupled to the laser beam scanner, controlling a rotation of each of the plurality of micromirrors of the at least one micromirror array, to reflect the pulsed laser beam to generate one or more output laser beams and to scan the output laser beams in two orthogonal directions according to a predefined scan pattern; anddirecting the output laser beams from the laser beam scanner to the patient's eye to form one or more focal spots that are scanned within an arear of the eye.9. The ophthalmic laser delivery method of claim 8 , wherein the laser beam scanner includes two micromirror ...

SYSTEMS AND METHODS FOR HIGH SPEED MODULATION OF A RESONANT SCANNER IN OPHTHALMIC LASER APPLICATIONS

An ophthalmic surgical laser system includes: a laser that produces a pulsed laser beam having a pulse energy and pulse repetition rate; a high frequency fast scanner; an XY-scan device; a Z-scan device; and a controller. The controller controls the high frequency scanner to produce a scan line having a scan width; controls the XY-scan device and the Z-scan device to carry out of first sweep of the scan line in a first sweep direction and to carry out a second sweep of the scan line in a second sweep direction that is not parallel to the first sweep direction thereby defining an overlap region. At least one of the pulse energy, repetition rate, XY-scan speed, and the scan width is varied so as to accelerate the cutting speed and reduce the exposure of ophthalmic tissue in the overlap region to multiple exposures of laser pulses configured to modify ophthalmic tissue. 111-. (canceled)12. A method for creating a lenticular incision using an ophthalmic surgical laser system , the method comprising the steps of:generating, with a laser, a pulsed laser beam to a target in a subject's eye; the pulsed laser beam having a pulse energy and pulse repetition rate;generating a scan line, the scan line having a scan width;controlling, via a controller, an XY-scan device and a Z-scan device to conduct a first sweep of the fast scan line in a first sweep direction;controlling, via the controller, the XY-scan device and the Z-scan device to conduct a second sweep of the scan line in a second sweep direction that is not parallel to the first sweep direction, thereby defining an overlap region;wherein at least one of the pulse energy, the repetition rate, XY-scan speed, and the scan width are varied during at least one of the first sweep and second sweep so as to reduce the exposure of ophthalmic tissue in the overlap region to multiple exposures of laser pulses configured to modify ophthalmic tissue.13. The method of claim 12 , wherein the ophthalmic surgical laser system further ...

SYSTEM AND METHOD FOR ANGLED OPTICAL ACCESS TO THE IRIDO-CORNEAL ANGLE OF THE EYE

A first optical subsystem includes a window with a refractive index nand an exit lens having a refractive index n. The exit lens is configured to couple to the window to define a first optical axis extending through the window and the exit lens. A second optical subsystem is configured to output a light beam. The light beam is directed to be incident at a convex surface of the exit lens along a second optical axis at an angle α that is offset from the first optical axis. The window is configured to detachably couple to the cornea of the eye such that the first optical axis is generally aligned with a direction of view of the eye. The respective refractive indices nand nare configured to direct the light beam incident at the convex surface of the exit lens through the cornea of the eye toward the irido-corneal angle. 1. An optical system for directing a light beam to an irido-corneal angle of an eye , the eye having a direction of view and a cornea with a refractive index n , the optical system comprising: [{'sub': 'w', 'a window formed of a material with a refractive index n, the window having a concave surface and a convex surface opposite the concave surface, and'}, {'sub': 'x', 'an exit lens formed of a material having a refractive index n, the exit lens having a concave surface and a convex surface opposite the concave surface, wherein the concave surface of the exit lens is configured to couple to the convex surface of the window to define a first optical axis extending through the window and the exit lens; and'}], 'a first optical subsystem comprisinga second optical subsystem configured to output a light beam, the light beam is directed to be incident at the convex surface of the exit lens along a second optical axis at an angle α that is offset from the first optical axis,', 'the concave surface of the window is configured to detachably couple to the cornea of the eye such that the first optical axis is generally aligned with the direction of view, and', {' ...

INTEGRATED SURGICAL SYSTEM AND METHOD FOR TREATMENT IN THE IRIDO-CORNEAL ANGLE OF THE EYE

Intraocular pressure in an eye is reduced by delivering each of a high resolution optical coherence tomography (OCT) beam and a high resolution laser beam through the cornea, and the anterior chamber into the irido-corneal angle along an angled beam path. The OCT beam provides OCT imaging for diagnostic purposes and surgery planning and monitoring, while the laser beam is configured to modify tissue. A volume of ocular tissue within an outflow pathway in the irido-corneal angle is modified to reduce a pathway resistance present in one or more of the trabecular meshwork, the Schlemm's canal, and the one or more collector channels by applying the laser beam to ocular tissue defining the volume to thereby cause photo-disruptive interaction with the ocular tissue to reduce the pathway resistance or create a new outflow pathway. 1. A method of reducing intraocular pressure in an eye having a cornea , an anterior chamber , and an irido-corneal angle comprising an aqueous humor outflow pathway formed of a trabecular meshwork , a Schlemm's canal , and one or more collector channels branching from the Schlemm's canal , the method comprising:delivering each of an optical coherence tomography (OCT) beam and a laser beam through the cornea, and the anterior chamber into the irido-corneal angle; andmodifying a volume of ocular tissue within the outflow pathway to reduce a pathway resistance present in one or more of the trabecular meshwork, the Schlemm's canal, and the one or more collector channels by applying the laser beam to ocular tissue defining the volume to thereby cause photo-disruptive interaction with the ocular tissue to reduce the pathway resistance or create a new outflow pathway.2. The method of claim 1 , wherein delivering each of an OCT beam and a laser beam comprises directing each beam to a first optical subsystem comprising a window coupled to the cornea and an exit lens coupled to the window.3. The method of claim 2 , wherein:the eye comprises a direction of ...

Interventional Treatments for VitreoRetinal-Interface Syndromes

A system and method are provided for treating VitreoRetinal-Interface Syndromes (VRS) by using a femtosecond laser system to relieve vitreoretinal adhesions in an eye. Operationally, fibers in the vitreous body are severed by the laser system to create Posterior Vitreous Detachments (PVD) that relieve the adhesions. In a first embodiment for the present invention, tissue material on selected planes within the vitreous body is photoaltered to sever the fibers. Sequentially, or alternatively, to the first embodiment, in another embodiment, fibers at or near the vitreoretinal interface of the eye are photoaltered for this same purpose. 1. A method for relieving traction forces caused by an adhesion between a container and fibers formed in a gelatinous material held within the container , the method comprising the steps of:defining an axis extending through the gelatinous material;establishing at least one plane extending through the gelatinous material inside the container, with the plane having a predetermined orientation relative to the axis; andphotoablating material in the plane to sever fibers in the gelatinous material for relieving the traction forces.2. A method as recited in wherein the establishing step further comprises the steps of:establishing a first plane in the gelatinous material, wherein the first plane is oriented substantially perpendicular to the axis; andestablishing a second plane in the gelatinous material, wherein the second plane is oriented substantially parallel to the axis.3. A method as recited in further comprising:a plurality of mutually parallel first planes; anda plurality of second planes wherein each second plane in the plurality is parallel to at least one other second plane, and each second plane is at least a distance r from the axis.4. A method as recited in wherein the gelatinous material and the container are anatomical components of an eye claim 1 , and wherein the gelatinous material forms the vitreous body of the eye.5. A ...

Systems and Methods for Laser Beam Direct Measurement and Error Budget

Embodiments of the present invention generally describe systems, devices, and methods for directly measuring pulse profiles during pulse delivery. In some embodiment, the pulse profiles may be measured while the pulse is delivered to ablate a material. Embodiments, may calculate ablation spot parameters based on the pulse profiles and may refine one or more subsequent laser pulses based on deviations from the calculated ablation spot parameters from desired ablation spot parameters. In some embodiments, a fluence profiler is provided. The fluence profiler may measure a pulse profile of a laser pulse from a portion of the laser pulse. The fluence profiler may utilize a UV radiation energy sensor device and a camera-based imager. The measurements from the UV radiation energy sensor device and the camera-based imager may be combined and scaled to provide a measured pulse profile that corresponds to the delivered pulse. 1. A method comprising:generating a first laser pulse;delivering a portion of the first laser pulse to a beam profiler;delivering a remainder of the first laser pulse to a material;ablating the material at a treatment plane with the remainder of the first laser pulse to create an ablation spot;measuring a pulse profile of the first laser pulse with the beam profiler;calculating ablation parameters that correspond to the ablation spot based on the measured pulse profile;adjusting a delivery of a second laser pulse to the material based on the measured pulse profile of the first laser pulse.2. The method of claim 1 , wherein the material comprises a tissue of an eye claim 1 , and wherein the beam profiler comprises a beam splitter for directing a first part of the portion of the first laser pulse to a ultraviolet radiation energy sensor and a second part of the portion of the first laser pulse to a camera-based imager.3. The method of claim 2 , wherein the camera-based imager comprises a UV-to-visible converter plate claim 2 , an image sensor claim 2 , and ...

Method of altering the refractive properties of an eye

The present invention relates to a method of altering the refractive properties of the eye, the method including applying a substance to a cornea of an eye, the substance configured to facilitate cross linking of the cornea, irradiating the cornea so as to activate cross linkers in the cornea, and altering the cornea so as to change the refractive properties of the eye.

Creation of curved cuts in the inside of the eye cornea

A device for isolating a lenticle in the cornea of an eye. The device includes: a laser beam source to emit pulsed laser radiation having a pulse frequency of 1.2 MHz to 10 MHz, a pulse energy of 1 nJ to 200 nJ and a wavelength penetrating the cornea; a beam-forming unit having beam optics with an image field and that bundles pulsed laser radiation into a focus located inside the image field, and which has a maximum diameter of less than 3 μm; a beam-deflection unit shifting the focus in the cornea and inside the image field, the focus moving along a path when the image field is resting; and a control unit to control the source and the beam-forming unit to isolate the lenticle by specifying the path. The lenticle is delimited by a cut surface which is curved with regard to a front surface of the cornea.

METHOD FOR LASER CUTTING A CORNEAL POCKET

A method for using a laser to create a pocket in a patient's cornea is provided. The pocket is created using a femtosecond or a nanosecond laser. The laser ablates tissue within the cornea in a specific shape. The shape of the pocket can be determined by software to custom program a three-dimensional path of the laser. A variety of corneal pocket configurations or computer programmed shapes can be used accommodate various corneal lens shapes and sizes. An intracorneal lens can then be inserted into the pocket, in order to correct the patient's vision. 1. A method for creating a corneal pocket and an entry channel for inserting and positioning an intracorneal lens in the corneal pocket , the method comprising:providing a low-energy femtosecond laser configured to create the corneal pocket;positioning the laser proximate to a cornea such that it can be used to create the corneal pocket;receiving an input for a generally curvilinear movement path and a first laser energy output in a range between approximately 0.2 microjoules and 1.5 microjoules for the laser to form the corneal pocket having a specific pocket shape and a thickness conforming to predefined surfaces of an intracorneal lens to be inserted into the corneal pocket;focusing a laser beam from the laser to a predetermined depth within the cornea between an anterior surface and a posterior surface of the cornea such that the laser beam ablates corneal tissue at a focal point at the predetermined depth;moving the laser beam in the generally curvilinear movement path in order to create the corneal pocket having the specific pocket shape and a thickness about the size of diameter of the laser beam focal point;forming the entry channel into the corneal pocket with the laser beam, wherein the entry channel is at an obtuse angle form the conical pocket toward an entry incision on the cornea; andforming a relaxing incision in a region of the cornea outside of the corneal pocket and the entry channel using a second ...

METHOD AND APPARATUS FOR PRECISION WORKING OF MATERIAL

A method for precise working of material, particularly organic tissue, comprises the step of providing laser pulses with a pulse length between 50 fs and 1 ps and with a pulse frequency from 50 kHz to 1 MHz and with a wavelength between 600 and 2000 nm for acting on the material to be worked. Apparatus, in accordance with the invention, for precise working of material, particularly organic tissue comprising a pulsed laser, wherein the laser has a pulse length between 50 fs and 1 ps and with a pulse frequency of from 50 kHz to 1 MHz is also described. 131-. (canceled)32. An apparatus for precision machining of an organic tissue , the apparatus comprising:a radiation source that produces a pulsed laser beam having a plurality of laser pulses;wherein the pulsed laser beam has a pulse length between 50 fs and 1 ps, a pulse frequency greater than 50 kHz, and an energy of an individual laser pulse between 100 nJ and 10 μJ; anda beam device that directs the pulsed laser beam,wherein the radiation source and the beam device are configured to apply the pulsed laser beam to the organic tissue that generates a plurality of cuts in the organic tissue by photodisruption, andwherein the plurality of the cuts divide a portion of the organic tissue into fragments capable of being extracted by a suction device.33. The apparatus according to claim 32 , further comprising:a holding mechanism that positions the organic tissue,wherein the holding mechanism includes an adapter and a vacuum suction ring for fixating a human eye.34. The apparatus according to claim 32 , further comprising:an operation microscope.35. The apparatus according to claim 34 ,wherein the beam device includes an objective of the operation microscope, andwherein the operation microscope has a beam splitter that reflects the pulsed laser beam into a beam path of the operation microscope.36. The apparatus according to claim 32 , wherein the suction device has a suction cannula.37. The apparatus according to claim 36 ...

APPARATUS AND METHOD FOR ENHANCING CORNEAL LENTICULAR SURGERY WITH LASER REFRACTIVE INDEX CHANGES

Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical tissues is performed in combination with corneal lenticular surgery to achieve overall desired vision corrections. 1. A method for correcting vision in a patient comprising:(a) generating cut surfaces in a cornea of an eye in order to correct ametropia using an apparatus, said apparatus comprising: a first laser unit, which focuses first pulsed laser radiation into the cornea and moves said focused radiation therein in order to generate cut surfaces within the cornea; and a control unit, which controls the first laser unit for generating cut surfaces such that a predetermined lenticle to be removed is separated from the surrounding corneal material within the cornea by at least one cut surface; and(b) modifying the refractive index of ocular tissue of the eye, by irradiating select regions of the ocular tissue with a focused, visible or near-IR second laser below the optical breakdown threshold of the tissue to provide refractive structures that exhibit a change in refractive index, and exhibit little or no scattering loss, and scanning over the select regions with the second laser such that ablation or removal of the tissue is not observed in the irradiated region.2. The method of claim 1 , wherein the focused claim 1 , visible or near-IR second laser has a pulse energy from 0.01 nJ to 10 nJ.3. The method of claim 1 , wherein step (a) achieves relatively gross refractive corrective changes in the eye claim 1 , and step (b) achieves further refinement corrections.4. The method of claim 3 , further comprising performing wavefront aberrometry diagnostics between steps (a) and (b) to determine further refinements to sphere claim 3 , cylinder or higher order aberrations to be corrected in step (b).5. The method of claim 1 , wherein the first laser and the second laser are the same laser claim 1 , and wherein the laser power and/or fluence is controlled ...

Method for controlling an eye surgical laser and treatment apparatus

A method for controlling a surgical laser for the separation of a volume body, with predefined posterior and anterior interfaces, from a human or animal cornea is disclosed. The method including controlling the laser by means of a control device such that it emits pulsed laser pulses in a shot sequence into the cornea. The interfaces are generated by the generation of a plurality of cavitation bubbles generated by photodisruption by means of an interaction of the individual laser pulses with the cornea. A minimum diameter of the volume body orthogonal to an optical axis of the volume body is determined depending on at least one diopter value for the volume body and on a preset thickness of the volume body viewed in a direction of the optical axis. A treatment apparatus, a computer program product and a computer-readable storage medium are also disclosed.

Modular intraocular lens designs, tools and methods

Modular IOL removal systems and methods that cut an optic portion of an intraocular in a single motion such to facilitate removal of the optic portion from an eye through an incision, for example a corneal incision, without increasing the size of the corneal incision. Various cutting tools having one or more blades may be utilized. The cut intraocular lens may have one continuous cut or be cut into multiple smaller pieces. The single cutting step may apply balanced forces and torque to avoid damaging the surrounding eye anatomy, reducing the risk of trauma. 131-. (canceled)32. A device configured for insertion into a capsular bag of an eye , the device comprising:an annular anterior portion;an annular posterior portion;an annular intermediate portion extending between the annular anterior portion and the annular posterior portion, wherein the annular intermediate portion protrudes radially outwardly from the annular anterior portion and the annular posterior portion, and wherein the annular intermediate portion has an exterior that includes an anterior facing surface and a posterior facing surface; anda passage extending through the annular anterior portion, the annular intermediate portion, and the annular posterior portion.33. The device of claim 32 , wherein the device further comprises a central longitudinal axis claim 32 , and wherein the anterior facing surface and the posterior facing surface extend transverse to the central longitudinal axis.34. The device of claim 33 , wherein the anterior facing surface extends perpendicular to the central longitudinal axis.35. The device of claim 32 , wherein a widest portion of the passage is within the annular intermediate portion.36. The device of claim 32 , wherein the annular intermediate portion and the annular posterior portion meet at a junction claim 32 , and wherein an exterior of the junction curves as the junction extends from the annular intermediate portion to the annular posterior portion.37. The device of ...

Method and system for modifying eye tissue and intraocular lenses

A system for ophthalmic surgery includes a laser source configured to deliver an ultraviolet laser beam comprising laser pulses having a wavelength between 320 nm and 370 nm to photodecompose one or more intraocular targets within the eye with chromophore absorbance. The pulse energy, the pulse duration, and the focal spot are such that an irradiance at the focal spot is sufficient to photodecompose the one or more intraocular targets without exceeding a threshold of formation of a plasma and an associated cavitation event. An optical system operatively coupled to the laser source and configured to focus the ultraviolet laser beam to a focal spot and direct the focal spot in a pattern into the one or more intraocular targets. The optical system focuses the laser beam at a numerical aperture that provides for the focal spot to be scanned over a scan range of 6 mm to 10 mm.

PRODUCING CUT SURFACES IN A TRANSPARENT MATERIAL BY MEANS OF OPTICAL RADIATION

A method for producing a cut surface in a transparent material using optical radiation. A laser device separates the material using optical radiation and includes an optical unit focussing the radiation along an optical axis into an image field defining an image-field size. A focal position is adjusted transversely along the axis, producing a cut surface extending substantially parallel to the axis and, in projection along the axis, is a curve having a maximum extent. The focus is displaced by adjustment of the focal position along a trajectory curve lying in the cut surface. The cut surface has a maximum extent which is greater than the image-field size. The focal position is moved transverse to the axis along the curve. The image field is displaced transversely, and the focal position is adjusted in an oscillating fashion along the axis on the curve between an upper and lower axial focus position. 1. A treatment apparatus for producing a cut in a transparent material , the apparatus comprising:a laser device which is adapted to generate a cut within the transparent material using optical radiation, the laser devicea control device which is connected to the laser device and controls the laser device such that a focus adjustment device moves the position of the focus of the optical radiation in the material along a path, wherein the control device controls the laser device such that the cut has, in projection along an optical axis, a form of a curve,2. A method for producing control data for producing a cut in a transparent material , whereinthe control data are designed for a laser device comprising: 'a focus adjustment device for moving a position of the focus,', 'optics configured to focus the optical radiation along an optical axis into a focus situated in the material and which have in the material an image field in which the focus lies and which has an image field size, and'}wherein the control data are produced to comprise data for the focus adjustment device ...

SYSTEM AND METHOD FOR LASER CORNEAL INCISIONS FOR KERATOPLASTY PROCEDURES

A first image of the eye is generated when the cornea of the eye is exposed to a gas. The cornea is covered with an optic of a patient interface. A second image of the eye with the patient interface over the cornea is generated. In this second image, the patient interface distorts the second image of the eye. One or more of a position or an orientation of the eye is determined in response to the first image and the second image when the patient interface has been placed over the cornea. 1. A method of treating a cornea of an eye , the method comprising:measuring a profile of a posterior portion of the cornea;incising the cornea with a beam pulse profile based on the profile of the posterior portion.2. The method of claim 1 , wherein the cornea is treated so as to inhibit light scatter at a treated posterior surface of the treated cornea.3. The method of claim 1 , further comprising:measuring folds of the posterior portion of the cornea, wherein the beam pulse profile extends along the posterior portion in response to the folds to inhibit transecting lamella of the stroma.4. The method of claim 1 , wherein the posterior portion comprises an irregular posterior surface claim 1 , and wherein the beam pulse profile provides an irregular incision profile corresponding to the irregular posterior surface.5. A method as in claim 4 , wherein the irregular posterior surface corresponds to folds of stromal lamella of the cornea and wherein the irregular incision profile decreases transaction of the stromal lamella.6. The method of claim 5 , wherein a donor cornea comprises an irregular donor posterior surface corresponding to donor folds of donor stromal lamella of the donor cornea and wherein an irregular donor incision profile corresponding to the donor folds of the donor stromal lamella decreases transaction of the donor stromal lamella.7. The method of claim 1 , wherein the profile corresponds to folds of a Descemet's membrane of the cornea and wherein the incision profile ...

Method for modifying the refractive index of ocular tissues

A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss.

Laser device and process for configuring such laser device

A process for configuring a laser device comprising: selecting a pulse length within a range from 1 ps to 1 ns; selecting a wavelength for the laser radiation within a range from 300 nm to 400 nm or within a range from 800 nm to 1100 nm; ascertaining a set of parameter values of the laser device that when the laser device is operated with these parameter values a two-dimensionally extensive separation of tissue of human corneal or lenticular tissue is achieved by stringing together local sites of damage, the set of parameter values including the selected pulse length, the selected wavelength, and values for at least one of the following parameters: a pulse energy, a pulse repetition rate, a fluence per radiation pulse, a number of pulses per site of damage, a scanning speed of a scanning apparatus of the laser device, and a focus diameter.

PHARMACEUTICAL COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION AND METHODS FOR FABRICATING THEREOF

Pharmaceutical compositions for intraocular injection are described, the compositions consisting essentially of a therapeutically effective quantity of an anti-bacterial agent (such as moxifloxacin), a therapeutically effective quantity of an anti-inflammatory agent (such as prednisolone), at least one pharmaceutically acceptable excipient and a pharmaceutically acceptable carrier. Methods for fabricating the compositions and using them for intraocular injections are also described. 1. A pharmaceutical composition , comprising: (a1) a therapeutically effective quantity of an anti-bacterial agent independently selected from the group consisting of quinolone, a fluorinated quinolone and pharmaceutically acceptable salts, hydrates, solvates or N-oxides thereof; and', '(a2) a therapeutically effective quantity of a corticosteroid independently selected from the group consisting of prednisone, prednisolone, methylprednisone, corticol, cortisone, fluorocortisone, deoxycorticosterone acetate, aldosterone, budesonide, derivatives or analogs thereof and pharmaceutically acceptable salts, hydrates, solvates, ethers, esters, acetals and ketals thereof;, '(a) a therapeutic component consisting essentially of(b) at least one pharmaceutically acceptable solubilizing and suspending agent selected from the group consisting of non-ionic polyoxyethylene-polyoxypropylene block copolymers; and(c) optionally, a pharmaceutically acceptable carrier therefor.2. The pharmaceutical composition of claim 1 , wherein the corticosteroid is selected from the group consisting of prednisone claim 1 , prednisolone claim 1 , methylprednisone and derivatives or analogs thereof.3. The pharmaceutical composition of claim 1 , wherein the anti-bacterial agent is a fluorinated quinolone.5. The pharmaceutical composition of claim 3 , wherein the fluorinated quinolone is selected from the group consisting of moxifloxacin and gatifloxacin.6. The pharmaceutical composition of claim 5 , wherein the fluorinated ...

OPTIMIZATION OF SPHERICAL ABERRATION PARAMETERS FOR CORNEAL LASER TREATMENT

A method for determining spherical aberration parameters for a corneal laser treatment to treat presbyopia may include performing pupillometry to measure various actual pupil diameters of a patient from a photopic diameter to a mesopic diameter. An actual pupil center of the patient may also be measured. The measured pupil diameters and the pupil center may be used to customize the spherical aberration parameters to the eye of the patient for improved ocular results after treatment. 1. A method for optimization of spherical aberration parameters for corneal laser treatments , the method comprising:performing pupillometry on a patient subject to a corneal laser treatment to measure respective pupil diameters including: a mesopic diameter, a normal light diameter, an accommodative reading diameter, and a photopic diameter;calculating an outer diameter for the spherical aberration that is greater than the mesopic diameter;calculating an inner diameter for the spherical aberration associated with an amplitude of the spherical aberration that corresponds to the photopic diameter;calculating the amplitude of the spherical aberration according to a refraction that induces myopia;calculating a slope of the spherical aberration extending from the photopic diameter to the normal light diameter; andusing the spherical aberration calculated, including the outer diameter, the inner diameter, the amplitude, and the slope, performing the corneal laser treatment on the patient.2. The method of claim 1 , wherein performing the pupillometry further comprises determining a pupil center of the pupil claim 1 , and further comprising:calculating a center of the spherical aberration based on the pupil center.3. The method of claim 1 , wherein the corneal laser treatment is a presbyopia treatment.4. The method of claim 1 , wherein the corneal laser treatment is performed using a laser-assisted in situ keratomileusis (LASIK).5. The method of claim 1 , wherein calculating the slope of the ...

System, method and material composition for use in correction of eye conditions

A system, technique and material composition for use in correction of eye condition are disclosed. The system comprising a processing utility and an etching utility. The processing utility comprises: correction pattern module configured for providing a selected two-dimensional pattern in according with input data indicative of vision impermanent of a user, and for generating operational instructions for forming said selected two-dimensional pattern on the surface of the cornea by said etching utility. The etching utility is configured to etching the selected patter on surface of the cornea of a user. The material composition comprises aqueous solution comprising a plurality of nanoparticles, said nanoparticles comprising maghemite nanoparticles wrapped by biocompatible protein chains. The material composition may be used as eye drops thereby allowing the nanoparticles to occupy etched region on the cornea, thereby maintaining correction of eye condition

Optical imaging and measurement systems and methods for cataract surgery and treatment planning

An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

Apparatus for patterned plasma-mediated laser ophthalmic surgery

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

LASER TREATMENT DEVICE

An adapter for coupling a laser treatment device to an object for treatment. The adapter has an input side, which may be fixed relative to the laser treatment device, by a locking mechanism and which may be fixed to the object, for alignment of the object relative to the laser treatment device. A scanned laser beam is introduced on the input side, from the laser treatment device, along a beam path to the object with a reference structure. The reference structure lies on the beam path of the adapter and may be optically detected by means of the laser beam scanned over the region. 1. (canceled)2. An adapter for coupling an eye to be treated in ophthalmic surgery with a laser treatment device , the adapter comprising:an adapter input side, being fixable relative to the laser treatment device via a locking mechanism;an adapter beam path,a scanned region that is part of the adapter input side, wherein a laser beam, having been supplied to be scanned over the scanned region, is transmitted along the adapter beam path, wherein the adapter beam path starts at the scanned region and the laser beam passes through the scanned region and along the adapter beam path when being scanned during laser treatment; anda reference structure, the reference structure being located in the adapter beam path such that the reference structure can be illuminated by laser radiation being scanned over the scanned region, wherein the reference structure is adapted to absorb or reflect the laser radiation to make the reference structure optically detectable; andwherein the reference structure encodes information about the adapter.3. The adapter as claimed in claim 2 , wherein the information encoded by the reference structure includes an adapter ID.4. The adapter as claimed in claim 2 , wherein the information encoded by the reference structure includes an adapter type.5. The adapter as claimed in claim 2 , further comprising an adapter output side claim 2 , through which laser radiation supplied ...

CORNEAL IMPLANT SYSTEMS AND METHODS

A system for forming a corneal implant includes a cutting apparatus, which includes a laser source that emits a laser and optical elements that direct the laser. The system includes a controller implemented with at least one processor and at least one data storage device. The controller generates a sculpting plan for modifying a first shape of a lenticule formed from corneal tissue and achieving a second shape for the lenticule to produce a corneal implant with a refractive profile to reshape a recipient eye. The sculpting plan is determined from measurements relating to the lenticule having the first shape and information relating to a refractive profile for a corneal implant. The controller controls the cutting apparatus to direct, via the one or more optical elements, the laser from the laser source to sculpt the lenticule according to the sculpting plan to produce the corneal implant with the refractive profile. 1. A system for forming a corneal implant , comprising: a laser source that emits a laser; and', 'one or more optical elements that direct the laser from the laser source;, 'a cutting apparatus including [ measurements relating to the lenticule having the first shape, and', 'information relating to a refractive profile for a corneal implant, and, 'generate a sculpting plan for modifying a first shape of a lenticule formed from corneal tissue and achieving a second shape for the lenticule to produce a corneal implant with a refractive profile to reshape a recipient eye, the sculpting plan determined from, 'control the cutting apparatus to direct, via the one or more optical elements, the laser from the laser source to sculpt the lenticule according to the sculpting plan to produce the corneal implant with the refractive profile., 'a controller implemented with at least one processor and at least one data storage device, the controller configured to2. The system of claim 1 , wherein the measurements relating to the lenticule include three-dimensional ...

METHOD AND APPARATUS FOR AUTOMATED PLACEMENT OF SCANNED LASER CAPSULORHEXIS INCISIONS

Systems and methods are described for cataract intervention. In one embodiment a system comprises a laser source configured to produce a treatment beam comprising a plurality of laser pulses; an integrated optical system comprising an imaging assembly operatively coupled to a treatment laser delivery assembly such that they share at least one common optical element, the integrated optical system being configured to acquire image information pertinent to one or more targeted tissue structures and direct the treatment beam in a 3-dimensional pattern to cause breakdown in at least one of the targeted tissue structures; and a controller operatively coupled to the laser source and integrated optical system, and configured to adjust the laser beam and treatment pattern based upon the image information, and distinguish two or more anatomical structures of the eye based at least in part upon a robust least squares fit analysis of the image information. 115-. (canceled)16. A system for cataract surgery on an eye of a patient , comprising:a. a laser source configured to produce a treatment beam comprising a plurality of laser pulses;b. an integrated optical system comprising an Optical Coherence Tomographer (OCT) coupled to a treatment laser delivery assembly such that the OCT and the treatment laser delivery assembly share at least one common optical element, the integrated optical system being configured to acquire image information pertinent to one or more targeted tissue structures and direct the treatment beam in a 3-dimensional pattern to cause breakdown in at least one of the targeted tissue structures;c. a patient support configured to maintain the eye of the patient within a range of the optical system; and 1) adjust the laser beam and treatment pattern based upon the image information,', '2) operate the OCT to perform one or more A-scans of at least one anatomical structure of the eye at each of a plurality of XY locations, thereby obtaining image information of a ...

SYSTEM AND APPARATUS FOR TREATING THE LENS OF AN EYE

A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided apparatus for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern. 113-. (canceled)14. A system for delivering lasers to a natural crystalline lens of an eye and for obtaining stereo images of the natural crystalline lens of the eye comprising:a. a first laser that generates a therapeutic laser beam of a predetermined first wavelength;b. a second laser that generates a second laser beam of a predetermined second wavelength;c. a scanner optically associated with the first laser beam and the second laser beam and the camera; wherein the scanner has the capability to provide stereo pairs of images of portions of the natural crystalline lens of the eye by delivering the first laser beam and the second Laser beam and deliver a laser beam from the first laser to the natural crystalline lens of the eye, wherein the redetermined first wavelength and a beam size of the first laser beam are such that the first laser beam travels entirely through ha cornea of the eye without significantly affecting the cornea prior to being delivered to the natural crystalline lens; andd. camera that receives the first laser beam and the second laser beam from the scanner and generates a stereo pair of images.15. (canceled)16. A system for delivering a laser beam to a natural crystalline lens of an eye comprising:a. a laser for producing, a laser beam of a predetermined wavelength;b. an optical path for directing the laser beam from the ...

METHOD AND APPARATUS FOR PERFORMING OPHTHALMIC PROCEDURES REMOVING UNDESIRABLE FEATURES USING LASER ENERGY

A method and system perform an ophthalmic procedure on an eye having an optical path from the lens to the retina. An image of at least part of the eye is received in a data processing unit. The image includes the optical path. The data processing unit determines keep out zone(s) and identifies undesirable feature(s) based on the image. The keep out zone(s) include the retina. The data processing unit also selects one of the undesirable feature(s) for removal. At least part of the undesirable feature is outside of the keep out zone(s). Confirmation for removal of the undesirable feature is received in the data processing unit. In response to receiving the confirmation, a control unit controls a laser to perform laser removal the at least the portion of the undesirable feature without targeting any portion of the keep out zone(s). 1. A method for performing an ophthalmic procedure on an eye including a lens and a retina , the eye having an optical path from the lens to the retina , the method comprising:receiving an image of at least a portion of the eye in a data processing unit of an ophthalmic laser system including the data processing unit and a control unit, the portion of the eye including the optical path;determining, using the data processing unit, at least one keep out zone based on the image, the at least one keep out zone including the retina;identifying, using the data processing unit, at least one undesirable feature based on the image;selecting, using the data processing unit, an undesirable feature of the at least one undesirable feature for removal, at least a portion of the undesirable feature residing outside of the at least one keep out zone;receiving confirmation for removal of the undesirable feature in the data processing unit; andin response to receiving the confirmation, controlling a laser via the control unit to perform laser removal of the at least the portion of the undesirable feature without targeting any portion of the at least one keep ...

Optical system for a laser therapy instrument

An optical system for a laser therapy instrument for the application of laser radiation on and in the eye, includes a femtosecond laser, an objective. The objective or at least one lens or lens group of the objective is shiftable in the direction of the optical axis being intended for shifting of the focus position from the region of the cornea to the region of the crystalline lens and vice versa. The optical system may include at least two optical assemblies designed for the axial variation of the focus of the therapeutic laser radiation, with the focus variation range Δz differing between the individual assemblies and a changing device, designed for the insertion of any one of these assemblies into the therapeutic laser beam path at a time.