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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 1742. Отображено 199.
10-02-2016 дата публикации

ПРОЦЕССОР ИЗОБРАЖЕНИЙ ДЛЯ ВНУТРИХИРУРГИЧЕСКОГО ИЗОБРАЖЕНИЯ ОПТИЧЕСКОЙ КОГЕРЕНТНОЙ ТОМОГРАФИИ ЛАЗЕРНОЙ ОПЕРАЦИИ ПО УДАЛЕНИЮ КАТАРАКТЫ

Номер: RU2014129752A
Принадлежит:

... 1. Хирургическая система для удаления катаракты, содержащая лазерный источник, выполненный с возможностью создания первой группы лазерных импульсов; направляющую оптику, присоединенную к лазерному источнику, выполненную с возможностью направлять первую группу лазерных импульсов в целевую область катаракты глаза; лазерный контроллер, выполненный с возможностью создавать электронное изображение целевого шаблона сканирования, и управлять направляющей оптикой для сканирования первой группой лазерных импульсов в соответствии с частью шаблона сканирования для создания первой фоторазрушаемой области в целевой области катаракты; систему изображения Спектральной Области Оптической Когерентной Томографии (СО-ОКТ), выполненную с возможностью создания изображения, содержащего части первой фоторазрушаемой области; и процессор изображения ОКТ, выполненный с возможностью выполнения анализа изображения, при том, что лазерный контроллер выполнен с возможностью создания электронного изображения измененного ...

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20-09-2015 дата публикации

СПОСОБ ЛЕЧЕНИЯ РОГОВИЦЫ И УСТРОЙСТВО ДЛЯ ЕГО ОСУЩЕСТВЛЕНИЯ

Номер: RU2014109590A
Принадлежит:

... 1.Устройство для лечения роговицы, содержащее запоминающее устройство (4), интерфейс (8), позволяющее получать и предоставлять данные, а также блок (6) обработки данных для вычисления и предоставления на интерфейс (8) офтальмологической величины, используемой при лечении роговицы,отличающееся тем, что также содержит блок (10) управления, предусмотренный для получения данных о начальном показателе (KC) центральной кератометрии и данных о значении начальной асферичности (QI) после их получения на интерфейс (8), сохранения этих данных в запоминающем устройстве (4), вызова блока (6) обработки данных о начальном показателе (KC) центральной кератометрии и значении начальной асферичности (QI), а также данных о значении целевой асферичности (QV) для вычисления показателя периферической кератометрии (KP), сохранения соответствующих данных в запоминающем устройстве (4) и предоставления их на интерфейс (8).2. Устройство по п. 1, отличающееся тем, что блок (6) обработки данных предусмотрен для вычисления ...

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28-10-2004 дата публикации

CHIRURGISCHES SYSTEM MIT VERTEILTEM EXCIMERLASER

Номер: DE0069727055T2

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25-02-2021 дата публикации

Verfahren zur Steuerung eines augenchirurgischen Lasers und Behandlungsvorrichtung

Номер: DE102019122166A1
Принадлежит:

Die Erfindung betrifft ein Verfahren zur Steuerung eines augenchirurgischen Lasers (18) für die Abtrennung eines Volumenkörpers (12) aus einer Kornea, durch Steuern des Lasers (18) mittels einer Steuereinrichtung (20) derart, dass dieser gepulste Laserpulse in einer Schussabfolge in einem vordefinierten Muster in die Kornea abgibt, wobei Grenzflächen (14, 16) des abzutrennenden Volumenkörpers (12) durch das vordefinierte Muster definiert sind und die Grenzflächen (14, 16) die Erzeugung einer Vielzahl durch Photodisruption erzeugter Kavitationsblasen (40) erzeugt werden, wobei die Vielzahl von Kavitationsblasen (40) entlang zumindest einer Kavitationsblasenbahn (42, 44) erzeugt wird und die Steuereinrichtung (20) die Schussabfolge des Lasers (18) zur Erzeugung eines vorgegebene Glattheitswerts derart steuert, dass zumindest zwischen benachbarten, auf der gleichen Kavitationsblasenbahn (42, 44) liegenden Kavitationsblasen (40) ein gemeinsamer Überlappungsbereich (46) der Kavitationsblasen ...

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15-10-2010 дата публикации

OPHTHALMI INSTRUMENT WITH WAVE FRONT MEASUREMENT

Номер: AT0000483397T
Принадлежит:

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15-03-2007 дата публикации

LASERVISUSKORREKTURAPPARAT

Номер: AT0000355810T
Принадлежит:

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15-11-2001 дата публикации

DEVICE FOR THE EXECUTION OF A SURGICAL INTERFERENCE AT THE CORNEA/CALLOSITY

Номер: AT0000208174T
Принадлежит:

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15-01-2005 дата публикации

DEVICE FOR THE FIGURATION OF THE CORNEA

Номер: AT0000286701T
Принадлежит:

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15-08-2003 дата публикации

EQUIPMENT FOR SEIZING AND CLEARING AWAY FROM CORNEA/CALLOSITY FABRIC TO CORRECTING THE AMETROPIE

Номер: AT0000245398T
Принадлежит:

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15-04-2003 дата публикации

DEVICE FOR CONTROL AND DEMOLITION OF EPITHELIUM THE EYE

Номер: AT0000235867T
Принадлежит:

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15-01-2004 дата публикации

SURGICAL SYSTEM WITH DISTRIBUTED EXCIMER LASER

Номер: AT0000257006T
Принадлежит:

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07-05-1997 дата публикации

Method and apparatus for improving vision

Номер: AU0007601396A
Принадлежит:

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04-05-2004 дата публикации

CUSTOMIZED TRANSITION ZONE SYSTEM AND METHOD FOR AN ABLATION PATTERN

Номер: AU2003284208A1
Принадлежит:

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04-05-2004 дата публикации

Customized transition zone system and method for an ablation pattern

Номер: AU2003284208A8
Принадлежит:

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16-01-2014 дата публикации

System and method for scanning a pulsed laser beam

Номер: AU2008323829B2
Принадлежит:

System (10) and method (100) of photoaitering a region of a materia! using a pulsed laser beam. The method includes randomly scanning the pulsed laser beam in the region, and creating a separation between a first layer of the material and a second layer of the material at the region. The system (10) includes a laser (14) producing a pulsed laser beam, a controller (22) transmitting a signal, and a scanner (20) coupled to the controller. The scanner randomly scans the pulsed laser beam in the region in response to the signal.

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30-07-2002 дата публикации

Topography-guided opthalmic ablation and eye-tracking

Номер: AU2002246521A1
Принадлежит:

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08-10-2009 дата публикации

Corneal implant system, interface, and method

Номер: AU2009231690A1
Принадлежит:

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18-12-2014 дата публикации

System and method for laser photoaltering a material using multi-beam scanning

Номер: AU2009322589B2
Принадлежит:

The present application relates to systems (10) and method of photoaltering a material. The system (10) includes a laser source (14) operable to produce a primary pulsed beam (18), a holographic optical element (32) configured to receive the primary pulsed beam (18) and transmit a plurality of secondary beams (36), and a scanner (20) operable to direct the secondary beams (36) to the material. The secondary beams (36) are based on the primary pulsed beam (18). The method includes phase shifting a pulsed laser beam to produce an input beam (36), holographically altering the input beam to produce a plurality of transmission beams (36), and scanning a portion of the material (12) with the transmission beams (36).

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27-06-2019 дата публикации

Calculation of actual astigmatism correction and nomographs for corneal laser treatment

Номер: AU2017397834A1
Принадлежит: Phillips Ormonde Fitzpatrick

A method for to calculation of actual astigmatism correction and nomographs for corneal laser treatment includes performing a post-operative measurement of the cornea of a patient to determine actual astigmatism coefficients. The actual astigmatism coefficients are compared against the expected astigmatism coefficients to generate a nomograph value or a nomograph curve over a sample population. The nomograph is used to calibrate subsequent laser treatments for improved accuracy of clinical results.

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09-12-1999 дата публикации

Excimer laser system for correction of vision

Номер: AU0000713834B2
Принадлежит:

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20-10-2009 дата публикации

SYSTEM AND METHOD FOR EVALUATING A SECONDARY LASIK TREATMENT

Номер: CA0002476333C
Автор: MARKMAN, HOWARD P.

A method and system are disclosed for evaluating the safety of a prospective secondary LASIK treatment to correct a person's vision. The difficulties with making an accurate, direct measurement of corneal thickness of a cornea having a pre-existing keratectomy are overcome by using pre-LASIK topography and pachymetry measurements, and per- and post-LASIK wavefront measurements to determine post-LASIK corneal thickness, and thus the suitability and safety of a prospective secondary LASIK procedure. A system embodiment (200) includes diagnostic (210) and computing (220) platforms for generating and analyzing data, and a device readable medium (250) for storing and transferring an instruction to a laser ablation system (290).

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24-08-2010 дата публикации

VARIABLE REPETITION RATE FIRING SCHEME FOR REFRACTIVE LASER SYSTEMS

Номер: CA0002485692C
Автор: WONG, JONATHAN
Принадлежит: VISX, INCORPORATED

Systems (10) and methods apply pulsed laser energy to an eye with a pulsed laser system. The laser system (10) includes a pulsed laser (12), a laser beam delivery system (16) and at least one processor (22). The laser (12) makes a beam (14) of an ablative light energy. A dimension across the laser beam (14) varies during a treatment of the eye (E). A firing rate of the laser (12) varies as the dimension across the beam (14) varies during the treatment. The dimension across the beam and the firing rate of the laser (12) can be arranged so as to maintain a power of the beam (14) applied to the eye at a substantially constant level during at least a portion of the treatment. A firing rate of the laser (12) for each pulse may be listed in a treatment table (140).

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01-11-2016 дата публикации

SYSTEM FOR INCISING MATERIAL

Номер: CA0002705233C
Принадлежит: AMO DEVELOPMENT, LLC, AMO DEV LLC

Systems (10) and methods (100) of incising a portion of a material include creating a sub-surface separation in a region of the material, and incising a periphery of the region with a pulsed laser beam to produce an edge of the portion. The edge includes a periodically varying shape to secure the portion to the material when the portion is reintegrated. The system (10) includes a laser (14) producing the pulsed laser beam, a scanner (20) operable in response to a control signal, and a controller (22) coupled to the scanner. The controller produces the control signal. In response to the control signal, the scanner creates a sub-surface separation in the region with the pulsed laser beam and incises the periphery of the region with the pulsed laser beam to produce the edge (72, 78, 84) with the periodically varying shape.

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04-07-2017 дата публикации

OPHTHALMIC LASER SYSTEM WITH HIGH RESOLUTION IMAGING AND KIT THEREFOR

Номер: CA0002731810C
Принадлежит: AMO DEVELOPMENT, LLC, AMO DEV LLC

System (10, 40) for photoaltering a region of an eye providing an ergonomical view of the eye throughout an ophthalmic procedure using a high resolution digital image of the eye. The system includes a laser assembly (14, 16, 20, 26, 28) for outputting a pulsed laser beam, an imaging system (34) for capturing a real-time high resolution digital image of the eye and displaying the digital image of the eye, a user interface (32) receiving at least one laser parameter input, and a controller (22) coupled to the laser assembly, imaging system, and user interface. The controller directs the laser assembly to output the pulsed laser beam to the region of the eye based on the laser parameter input.

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30-12-2001 дата публикации

METHOD FOR CUSTOM CORNEAL CORRECTIONS

Номер: CA0002323842A1
Принадлежит:

A method for customizing corneal corrections includes superposing an imaginary reference field (grid) on the anterior surface of the cornea of an eye to divide the corneal surface into reference areas. Also, a diagnostically determined refractive power map for the cornea is created. An incising laser beam is then directed through an individual reference area to a focal spot. Next, movement of the focal spot along the laser beam path is selectively accomplished to photoalter a predetermined volume of stromal tissue. Subsequently, based on the refractive power map, the predetermined volume of stromal tissue that is to be photoaltered is identified for each specific reference area. Accordingly, the steps of directing the beam and moving the focal spot are then repeated using selected reference areas until the required corneal correction is achieved.

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08-01-2004 дата публикации

LASER VISION CORRECTION APPARATUS AND CONTROL METHOD

Номер: CA0002490650A1
Принадлежит:

A device readable medium for use in controlling a laser vision, correction system includes a storage structure having stored therein a pre-programmed first, readable, corrective instruction reference that corresponds to an encoded customized corrective instruction determined by a calculation module external to the medium. The encoded, customized corrective instruction is executable by a laser vision correction laser platform for correction of a refractive defect when the corrective instruction reference is properly recognized. A laser vision correction system including the device readable medium is . described. A remunerative model relating to the device readable medium is disclosed.

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05-01-2021 дата публикации

INTEGRATED OPHTHALMIC SURGICAL SYSTEM

Номер: CA3026538C
Принадлежит: NOVARTIS AG

An ophthalmic surgical system includes a chassis comprising a laser source. The system includes a gantry coupled to the chassis. The position of the gantry is adjustable. The system includes a reference interface coupled to the gantry. The reference interface comprises an attachment interface at a distal portion of the reference interface, configured to couple to a patient interface for docking with an eye. The reference interface is configured to move to a first plate position proximal to the chassis and a second plate position distal from the chassis. The system further includes an optical head unit coupled to the reference interface. The optical head unit comprises a laser scanner and a beam splitter. The optical head unit is configured to move to a first head unit position near a proximal end of the reference interface and a second head unit position which is a lockable surgical position near a distal end of the reference interface.

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14-06-2011 дата публикации

TRACKING TORSIONAL EYE ORIENTATION AND POSITION

Номер: CA0002487411C
Автор: CHERNYAK, DIMITRI
Принадлежит: VISX, INC.

Methods and systems for tracking a position and torsional orientation of a patient's eye. In one embodiment, the present invention provides methods and software for registering a first image of an eye (56, 64) with a second image of an eye (66). In another embodiment, the present invention provides methods and software for tracking a torsional movement of the eye. In a particular usage, the present invention tracks the torsional cyclorotation and translational movement of a patient's eye so as to improve the delivery of a laser energy (12, 76) to the patient's cornea.

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15-03-2016 дата публикации

CORNEAL IMPLANT SYSTEM, INTERFACE, AND METHOD

Номер: CA0002720509C
Принадлежит: AMO DEVELOPMENT LLC, AMO DEV LLC

System, graphical user interface, and method for performing ophthalmic surgery on a cornea. The system includes a display (84) presenting a plurality of images representing corneal implants, a laser assembly (86) outputting a pulsed laser beam, and a control unit (82) coupled to the laser assembly and display. The control unit directs the laser assembly to produce a cavity in the cornea via the pulsed laser beam in response to a selected image, and the cavity receives a corneal implant corresponding to the selected image.

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26-11-1990 дата публикации

METHOD FOR RESHAPING THE CORNEA

Номер: CA0002013954A1
Принадлежит:

A method for reshaping the cornea comprises an initial step of determining the precise volume of corneal tissue which must be removed in order to attain the desired vision correction. A pulsed laser beam, having a pulse energy density sufficient to cause photoablation of corneal tissue near the threshold of the plasma regime, is directed onto the eye for removal of relatively large portions of tissue from the precisely determined volume to establish a corrected surface. A pulsed laser beam, having a pulse energy density sufficient to cause photoablation of corneal tissue substantially below the threshold of the plasma regime, is then directed onto the corrected surface to take away relatively small portions of corneal tissue and thereby smooth the corrected surface.

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28-04-1997 дата публикации

APPARATUS FOR REMOVING CORNEAL TISSUE WITH INFRARED LASER RADIATION

Номер: CA0002185779A1
Принадлежит: RIDOUT & MAYBEE LLP

A surgical technique for removing corneal tissue with scanned infrared radiation is disclosed which utilizes short midinfrared laser pulses to provide a tissue removal mechanism based on photospallation. Photospallation is a photomechanical ablation mechanism which results from the absorption of incident radiation by the corneal tissue. Since photospallation is a mechanical ablation process, very little heat is generated in the unablated adjacent tissue. The disclosed surgical system includes a scanning beam delivery system which allows uniform irradiation of the treatment region and utilizes low energy outputs to achieve controlled tissue removal. A real-time servocontrolled dynamic eye tracker, based on a multiple-detector arrangement, is also disclosed which senses the motion of the eye and provides signals that are proportional to the errors in the lateral alignment of the eye relative to the axis of the laser beam. Temporal and frequency discrimination are preferably utilized to distinguish ...

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10-09-2000 дата публикации

INTERACTIVE CORRECTIVE EYE SURGERY SYSTEM WITH TOPOGRAPHY AND LASER SYSTEM INTERFACE

Номер: CA0002300324A1
Принадлежит:

A system and method for correcting corneal irregularities through reshaping of an eye's cornea to provide a desired corrective corneal curvature. A preferred embodiment of the invention includes a topography device for mapping in detail the irregularities and surface deviations of a cornea, an interface system for receiving and manipulating topographical data and for providing directions to a laser system or the like to carry out a predetermined ablation profile on a substrate such as a corneal stroma and for providing a variety of actual and simulated pre and post operative visual depictions. The interface system, which can be a stand alone item, provides a tool for use by a surgeon or the like which allows a surgeon to input his expertise in the development of a clinical ablation profile that is well suited for the eye characteristics, review and also simulate a wide variety of potential surgical alternatives for a wide variety of corneal defects including irregular eye shapes and corneal ...

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02-02-2010 дата публикации

INTERACTIVE CORRECTIVE EYE SURGERY SYSTEM WITH TOPOGRAPHY AND LASER SYSTEM INTERFACE

Номер: CA0002300324C
Принадлежит: RUIZ, LUIS ANTONIO, RUIZ LUIS ANTONIO

A system and method for correcting corneal irregularities through reshaping of an eye's cornea to provide a desired corrective corneal curvature. A preferred embodiment of the invention includes a topography device for mapping in detail the irregularities and surface deviations of a cornea, an interface system for receiving and manipulating topographical data and for providing directions to a laser system or the like to carry out a predetermined ablation profile on a substrate such as a corneal stroma and for providing a variety of actual and simulated pre and post operative visual depictions. The interface system, which can be a stand alone item, provides a tool for use by a surgeon or the like which allows a surgeon to input his expertise in the development of a clinical ablation profile that i s well suited for the eye characteristics, review and also simulate a wide variety of potential surgical alternatives for a wide variety of corneal defects including irregular eye shapes and corneal ...

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29-02-2012 дата публикации

LASER VISION CORRECTION APPARATUS

Номер: KR0101113396B1
Автор:
Принадлежит:

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09-10-2012 дата публикации

Method, System and Algorithm Related to Treatment Planning for Vision Correction

Номер: KR1020120110176A
Автор:
Принадлежит:

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13-05-2010 дата публикации

SYSTEM AND METHOD FOR DEFINING AND CONTROLLING LTK AND OTHER SURGICAL EYE PROCEDURES TO PRODUCE LITTLE OR NO STROMAL COLLAGEN SHRINKAGE

Номер: KR1020100050555A
Автор: • BERRY MICHAEL J.
Принадлежит:

One or more treatment parameters are determined for a cornea reshaping procedure. The one or more treatment parameters are selected so as to reduce an amount of collagen shrinkage in a cornea of a patient's eye caused by the cornea reshaping procedure. For example, the one or more treatment parameters could be selected so as to minimize an amount of stromal collagen shrinkage in the cornea of the patient's eye caused by the cornea reshaping procedure. As another example, the cornea reshaping procedure could include irradiating multiple spots on the cornea of the patient's eye, where each spot is associated with an amount of stromal collagen. The one or more treatment parameters could be selected so that no more than 1% or 5% of the stromal collagen in the irradiated spots undergoes clinically significant shrinkage as a result of the cornea reshaping procedure. COPYRIGHT KIPO & WIPO 2010 ...

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01-08-2000 дата публикации

SHAPE EQUIPMENT THE CÓRNEA

Номер: BR0PI9808977A
Принадлежит:

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20-11-2008 дата публикации

COMBINED WAVEFRONT AND TOPOGRAPHY SYSTEMS AND METHODS

Номер: WO000002008141304A2
Принадлежит:

Methods, software, and systems are provided for determining an ablation target shape for a treatment for an eye of a patient. Techniques include determining wavefront information from the eye of the patient with a wavefront eye refractometer, determining anterior corneal shape information from the eye with a corneal topography device, and combining the wavefront information and the anterior corneal shape information to determine the ablation target shape.

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19-03-2009 дата публикации

APPARATUS, SYSTEMS AND TECHNIQUES FOR INTERFACING WITH AN EYE IN LASER SURGERY

Номер: WO000002009036098A3
Автор: KURTZ, Ronald, M.
Принадлежит:

Apparatus, techniques and systems are provided for interfacing with an eye in laser surgery.

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13-02-2003 дата публикации

DETERMINING A TARGET OPTICAL ZONE FOR ABALATION BASED ON THE STILES-CRAWFORD EFFECT

Номер: WO0003011111A2
Автор: MARROU, Lance, R.
Принадлежит:

The optimal optical zone for a patient is determined based upon the Stiles-Crawford effect and patient-specific scotopic pupil parameters. This invention is especially useful in refractive surgery where the chosen optical zone is crucial and affects both the depth and volume of the abalation. This optimal optical zone may be used in the creation of corrective lenses and other ocular surgery in addition to refractive surgery. Provided with the optimal optical zone, a refractive surgeon may better choose the sugical parameters for the treatment. Current methods consist of choosing a default value for all patients or only choosing the scotopic pupil diameter or contour, either of wich may not be optimal and may lead to a deeper or bigger treatment.

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17-07-2012 дата публикации

Compound modulation transfer function for laser surgery and other optical applications

Номер: US0008220925B2

Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

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30-06-2005 дата публикации

Ablation method using a laser beam and device for ablation

Номер: US20050143716A1
Принадлежит:

A method and an apparatus for evaluating ablation conditions easily and for ablating a target object accurately. The method includes irradiating a reference object with a laser beam under laser irradiation conditions determined to form a second curved surface shape on the reference object having a first curved surface shape approximate to a curved surface shape of the target object, measuring a third curved shape which has actually been formed by the laser irradiation, and determining a discrepancy between the second and the third curved surface shapes. Then, data about ablation or data for controlling a laser irradiation apparatus are corrected based on results of the determination.

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31-01-2002 дата публикации

Customized laser ablation of corneas with solid state lasers

Номер: US20020013575A1
Автор: Ming Lai, Meijuan Yuan
Принадлежит:

A surgical laser system is described for customized ablation with a power stabilized, near diffraction-limited laser beam. This surgical laser beam has a pulse repetition rate of from near 500 Hz to about 1 kHz and has a relatively small spot size at both positions of the cornea and the scanner. Such a surgical laser beam enables the use of fast scanner and the implement of fast eye tracker. One embodiment of such a surgical laser source is a CW pumped solid state laser employing non-linear wavelength conversion.

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20-06-2002 дата публикации

Interactive corrective eye surgery system with topography and laser system interface

Номер: US2002075451A1
Автор:
Принадлежит:

A system and method for correcting corneal irregularities through reshaping of an eye's cornea to provide a desired corrective corneal curvature. A preferred embodiment of the invention includes a topography device for mapping in detail the irregularities and surface deviations of a cornea, an interface system for receiving and manipulating topographical data and for providing directions to a laser system or the like to carry out a predetermined ablation profile on a substrate such as a corneal stroma and for providing a variety of actual and simulated pre and post operative visual depictions. The interface system, which can be a stand alone item, provides a tool for use by a surgeon or the like which allows a surgeon to input his expertise in the development of a clinical ablation profile that is well suited for the eye characteristics, review and also simulate a wide variety of potential surgical alternatives for a wide variety of corneal defects including irregular eye shapes and corneal ...

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03-10-2002 дата публикации

Apparatus and method for shrinking collagen

Номер: US2002143322A1
Автор:
Принадлежит:

The present invention provides a device, a system, and associated methods for advantageously treating bodily tissues containing collagen, such as the cornea. The device is a topical device that, when placed over the target tissue, defines a space between an inner surface of the device and the tissue. The radiation-transparent device allows radiation to pass therethrough to the tissue during the radiation treatment. The device is believed to reduce heat loss, such as evaporative heat loss, from the tissue, thereby improving the tissue-heating efficiency of the radiation treatment. Typical radiation treatment parameters may thus be adjusted to provide a more gentle, yet highly efficient treatment using the inventive device. The gentle treatment reduces the likelihood of thermally traumatizing the treated tissue. While the invention has particular application in the area of corneal treatment, it may be used to prepare other tissues or substrates.

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22-05-2012 дата публикации

Intrastromal refractive correction systems and methods

Номер: US0008182471B2
Автор: Kingman Yee, YEE KINGMAN

Devices, systems, and methods for laser eye surgery selectively ablate tissues within the cornea of an eye along one or more target surfaces, so that corneal tissue bordered by the laser incision surface(s) can be mechanically removed. An appropriate tissue-shaping surface can be selected based on the regular refractive error of the eye, and a shape of the target laser surface(s) can be calculated so as to correct irregular refractive errors of the eye, impose desired additional sphero-cylindrical and/or irregular alterations.

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28-04-2022 дата публикации

SYSTEMS AND METHODS FOR OCULAR LASER SURGERY AND THERAPEUTIC TREATMENTS

Номер: US20220125639A1
Принадлежит:

Disclosed are systems, devices and methods for laser microporation for rejuvenation of tissue of the eye, for example, regarding aging of connective tissue and rejuvenation of connective tissue by scleral rejuvenation. The systems, devices and methods disclosed herein restore physiological functions of the eye including restoring physiological accommodation or physiological pseudo-accommodation through natural physiological and biomechanical phenomena associated with natural accommodation of the eye. In some embodiments, the laser system may be configured to treat ocular tissue off axis or in a region of the eye which is distinct from the visual axis or directed away from the pupil of the eye where the gaze of the eye is.

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04-09-2001 дата публикации

遠視を矯正するための角膜表面切除システム及び方法

Номер: JP2001513376A
Принадлежит:

... 本発明は、目の角膜表面に選択的切除を施して、所望の角膜形状が得られるようにするための、とりわけ、角膜表面にレーザ・スカルプティングを施して、その曲率を増すことによって遠視/乱視状態を矯正するためのシステム、方法、及び、装置である。本発明の態様の1つでは、方法に、レーザ・ビームを目の角膜表面に当てるステップと、遠視及び乱視の光学特性を備えた初期曲率から矯正によって改善された光学特性を備える術後曲率に、角膜表面を変化させるステップが含まれている。角膜前面の曲率を増すことによって、遠視が矯正され、同時に、角膜組織のシリンドリカル・ボリュメトリック・スカルプティングを施すことによって、乱視が矯正される。遠視及び乱視矯正は、目の角膜前面に光矯正ゾーンを設け、光矯正ゾーンの一部に長方形切除(すなわち、シリンドリカル矯正)が施されるように設計された可変開口素子(35)にレーザ・ビームを通すことによって実施されるのが望ましい。次に、選択された量ずつ、レーザ・ビームを光矯正ゾーンを横切って変位させると、光矯正ゾーンに一連の長方形切除が施され、角膜表面の曲率が増して、遠視屈折障害が矯正されることになる。 ...

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02-02-2005 дата публикации

Номер: JP0003615487B2
Автор:
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20-03-2013 дата публикации

УСТРОЙСТВО ДЛЯ ЛАЗЕРНО-ОПТИЧЕСКОЙ ХИРУРГИИ ГЛАЗА

Номер: RU2477629C2
Принадлежит: УЭЙВЛАЙТ АГ (DE)

Группа изобретений относится к медицине и медицинской технике, и именно, к устройствам и способам для лазерной хирургии глаза. Устройство содержит источник импульсного фемтосекундного лазерного излучения и оптические компоненты, направляющие лазерное излучение и фокусирующие его на оперируемый участок на поверхности или внутри глаза. При этом оптические компоненты содержат линзы, установленные последовательно на траектории лазерного излучения, и, по меньшей мере, одна из линз выполнена настраиваемой по положению относительно других линз в направлении распространения лазерного пучка. Для регулировки указанной настраиваемой линзы устройство содержит исполнительное средство, блок управления, выполненный с возможностью: доступа к результатам измерений, относящимся к топографии поверхности глаза, расчета на основе топографических измерений профиля управляемого перемещения указанной линзы, который задает для всех точек сканирования в плоскости х-у в каждый момент времени номинальное положение, в которое нужно установить указанную настраиваемую линзу, и управления исполнительным средством, основываясь на указанном профиле управляемого перемещения. Способ включает в себя расчет профиля управляемого перемещения указанной линзы на основе топографических измерений и генерирование управляющего сигнала для исполнительного средства на основе определенного профиля управляемого перемещения. Использование группы изобретений позволит обеспечить постоянство толщины срезаемого лоскута в случае движений глаз в процессе операции. 2 н. и 11 з.п. ф-лы, 3 ил. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 477 629 (13) C2 (51) МПК A61F 9/01 (2006.01) A61B 18/20 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2009114667/14, 20.04.2009 (24) Дата начала отсчета срока действия патента: 20.04.2009 (72) Автор(ы): ФОГЛЕР Клаус (DE), КИТТЕЛЬМАНН Олаф (DE) (73) Патентообладатель(и): УЭЙВЛАЙТ АГ (DE) R U Приоритет(ы): (30) Конвенционный ...

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11-08-2017 дата публикации

СПОСОБ ЛЕЧЕНИЯ ПРЕСБИОПИИ

Номер: RU2016103768A
Принадлежит:

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15-08-1999 дата публикации

DEVICE FOR THE FIGURATION OF THE CORNEA OF MEANS OF WIDE LASER DEMOLITION

Номер: AT0000183068T
Принадлежит:

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15-08-2011 дата публикации

PROFILES FOR TRANSFERRED ABLATION WITH THE TREATMENT OF IRREGULAR ASTIGMATISM

Номер: AT0000516785T
Принадлежит:

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15-07-2008 дата публикации

SURGICAL APPARATUS FOR THE MINIMIZATION OF THE ASTIGMATISM, TOPOGRAPHIC AND REFRAKTIV MEASURED

Номер: AT0000400240T
Принадлежит:

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15-07-2008 дата публикации

DEVICE FOR THE PHOTO ABLATION OF THE KORNEA WITH A LASER BEAM

Номер: AT0000398433T
Принадлежит:

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15-07-2006 дата публикации

LENS PROFILE FOR EYES FOR CORRECTING DEFECTIVE VISIONS IN CONNECTION WITH ASTIGMATISM

Номер: AT0000332511T
Принадлежит:

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30-10-1995 дата публикации

Correction of vision through overlapping cylindrical lenses

Номер: AU0002257295A
Принадлежит:

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16-10-1996 дата публикации

Method of evaluating a laser used in ophthalmological surger y

Номер: AU0005257396A
Принадлежит:

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18-03-2021 дата публикации

Laser methods and systems for addressing conditions of the lens

Номер: AU2021200326A1
Принадлежит:

LASER METHODS AND SYSTEMS FOR ADDRESSING CONDITIONS OF THE Systems and methods for performing laser cataract surgery, for using a biometric system to determine a material property of a structure of the eye, laser pulses in a laser shot pattern having different powers. A therapeutic laser, and laser delivery system having the capability to vary the power of the laser beam.

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17-09-2015 дата публикации

Registration of corneal flap with ophthalmic measurement and/or treatment data for lasik and other procedures

Номер: AU2010295571B2
Принадлежит:

Systems and methods are disclosed for registering a corneal flap for laser surgery on an eye. The method includes generating a first image of the eye (300) during a diagnostic procedure, determining a corneal flap geometry (305) referenced to the first image, generating a second image of the eye (310) during to a treatment procedure, comparing the first image with the second image (315), and registering the corneal flap geometry of the first image to the second image (320).

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05-07-2012 дата публикации

Ophthalmic systems and related methods

Номер: AU2010325876A1
Принадлежит:

Systems and methods for modifying an eye including a light source with light elements, a photodetector producing a signal representing images of the light elements and corresponding to locations on an ocular surface, an optical system directing light from the light elements reflected by the ocular surface onto the photodetector, a memory including code for processing the signal, and a processor for executing the code and outputting shape data for use in calculating a treatment plan for the eye. The code includes instructions for determining the shape data based on a combination of zonal reconstruction and polynomial fitting using the plurality of images.

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14-03-2019 дата публикации

In situ determination of refractive index of materials

Номер: AU2014293542B2
Принадлежит: FPA Patent Attorneys Pty Ltd

A laser eye surgery system focuses light along a beam path to a focal point having a location within a lens of the eye. The refractive index of the lens is determined in response to the location. The lens comprises a surface adjacent a second material having a second refractive index. The beam path extends a distance from the surface to the focal point. The index is determined in response to the distances from the surface to the targeted focal point and from the surface to the actual focal point, which corresponds to a location of a peak intensity of an optical interference signal of the focused light within the lens. The determined refractive index is mapped to a region in the lens, and may be used to generate a gradient index profile of the lens to more accurately place laser beam pulses for incisions.

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09-11-2017 дата публикации

Laser methods and systems for addressing conditions of the lens

Номер: AU2016249405A1
Принадлежит: Spruson & Ferguson

Systems and methods for performing laser cataract surgery, for using a biometric system to determine a material property of a structure of the eye, laser pulses in a laser shot pattern having different powers. A therapeutic laser, and laser delivery system having the capability to vary the power of the laser beam.

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30-12-1996 дата публикации

Method for surgically achieving minimum astigmatism measured refractively and topographically

Номер: AU0005490396A
Принадлежит:

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05-10-2017 дата публикации

System for scanning a pulsed laser beam

Номер: AU2014228352B2
Принадлежит: Davies Collison Cave Pty Ltd

Systems and methods of photoaltering a region of a material using a pulsed laser beam. The method includes scanning the pulsed laser beam in a first portion of the region with a first pattern, scanning the pulsed laser beam in a second portion of the region with a second pattern, and separating a flap of the material at the region. The system includes a laser, a controller selecting at least first and second patterns, and a scanner operable in response to the controller. The first pattern has a first maximum acceleration associated with the second portion, and the second pattern has a second maximum acceleration associated with the second portion. The second maximum acceleration is less than the first maximum acceleration. The scanner scans the pulsed laser beam from the laser in the first portion with the first pattern and in the second portion with the second pattern.

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13-10-2016 дата публикации

Technique for treating presbyopia

Номер: AU2013394132B2
Принадлежит: Davies Collison Cave Pty Ltd

A system and method for reshaping a cornea of a patient's eye to treat presbyopia are disclosed as well as a method of generating a computer program for use in such system. Ray tracing is used to determine an ablation pattern that defines an amount of corneal tissue to be ablated, wherein the ablation pattern achieves a pre-defined amount of at least one of sphere, spherical aberration, coma, and astigmatism in the eye.

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23-10-2014 дата публикации

CORNEAL TOPOGRAPHY MEASUREMENT AND ALIGNMENT OF CORNEAL SURGICAL PROCEDURES

Номер: CA3136577A1
Принадлежит:

Methods and apparatus are configures to measure an eye without contacting the eye with a patient interface, and these measurements are used to determine alignment and placement of the incisions when the patient interface contacts the eye. The pre-contact locations of one or more structures of the eye can be used to determine corresponding post-contact locations of the one or more optical structures of the eye when the patient interface has contacted the eye, such that the laser incisions are placed at locations that promote normal vision of the eye. The incisions are positioned in relation to the pre-contact optical structures of the eye, such as an astigmatic treatment axis, nodal points of the eye, and visual axis of the eye.

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15-07-2004 дата публикации

PARAMETRIC MODEL BASED ABLATIVE SURGICAL SYSTEMS AND METHODS

Номер: CA0002507998A1
Принадлежит:

Example systems and methods for performing individually customized corneal ablative surgery is presented. The example systems and methods rely on a parametric model that correlates corneal measurements with predicted post- operative results and algorithm updates that facilitate achieving desired post- operative results.

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11-01-2018 дата публикации

LENTICULAR LASER INCISION USING WAVEFRONT GUIDED MAPS

Номер: CA0003030002A1
Принадлежит:

Embodiments generally relate to systems and methods for lenticular laser incisions based on wavefront maps. In an embodiment, a method comprises obtaining a wavefront map of a free eye using wavefront aberrometry to measure a refractive error, obtaining an iris image for the free eye using wavefront aberrometry, determining a free eye cutting profile to cut the cornea based on the wavefront measurement, determining a first translation of the free eye cutting profile based on estimated perturbation of the eye with a docking patient interface, docking the eye to a patient interface of an ultrashort pulsed laser system, obtaining an iris image for the docked eye, determining a second translation of the cutting profile for the docked eye from the free eye, using comparisons between the two iris images, and incising a bottom surface incision in the cornea based on the two translated cutting profiles.

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24-09-2013 дата публикации

IRIS RECOGNITION AND TRACKING FOR OPTICAL TREATMENT

Номер: CA0002628387C

A system and method are provided in which an iris or eye image is taken during a refractive diagnostic analysis. The image is employed for aligning data from the analysis with data from other refractive analysis instruments, as well as aligning a refractive surgical tool, such as a laser, with the eye for treatment. Further, the stored iris image is compared with the patient's iris before treatment, verifying that the correct eye is to be treated with a developed treatment pattern. A variety of refractive instruments can be used, such as corneal topography systems and wavefront aberration systems.

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06-05-2010 дата публикации

APPARATUS AND METHOD FOR PROVIDING A LASER SHOT FILE

Номер: CA0002740541A1
Принадлежит:

The invention relates to an apparatus, an algorithm and a method for providing a laser shot file for use in a laser. The laser may be an excimer laser. The shot file may be applied for performing a refractive laser treatment of an eye or for producing a customized contact lens or an intraocular lens. According to the invention information with respect to a desired ablation profile is provided and a first series of laser shot positions is calculated based on the desired ablation profile. A simulated ablation profile is generated using said first series of laser shot positions and using information about pulse characteristics of a single laser shot. The simulated ablation profile is compared with the desired ablation profile and residual structures are determined.

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11-12-2018 дата публикации

IMAGING SURGICAL TARGET TISSUE BY NONLINEAR SCANNING

Номер: CA0002778264C
Принадлежит: ALCON LENSX, INC., ALCON LENSX INC

Systems and techniques for laser surgery based on imaging a target tissue by nonlinear scanning are presented. In one implementation, a method for guiding an eye surgery can include the steps of: positioning an eye in relation to an imaging system; creating first scan data by determining a depth of an eye target region at a first set of points along a first arc; creating second scan data by determining a depth of the eye target region at a second set of points along a second arc; determining target region parameters based on the first and second scan data; and adjusting one or more surgical position parameters according to the determined target region parameters.

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27-06-2013 дата публикации

INTRA-SURGICAL OPTICAL COHERENCE TOMOGRAPHIC IMAGING OF CATARACT PROCEDURES

Номер: CA0002857338A1
Принадлежит:

A cataract surgical system includes a laser source to generate a first set of laser pulses; a guiding optic to guide the first set of laser pulses to a cataract target region in an eye; a laser controller to generate an electronic representation of a target scan pattern, and to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the cataract target region; and a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system to generate an image of a portion of the first photo-disrupted region. The laser controller can generate an electronic representation of a modified scan pattern in relation to the image generated by the SD-OCT imaging system, and control the guiding optic to scan a second set of laser pulses according the modified scan pattern.

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28-03-2013 дата публикации

DEVICE AND METHOD TO ASSIST TREATMENT OF THE CORNEA

Номер: CA0002848312A1
Автор: HEHN FREDERIC
Принадлежит:

Un dispositif d'aide au traitement ...

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25-07-2017 дата публикации

ASSESSMENT OF TOPOGRAPHIC SEMI-MERIDIAN PARAMETERS FOR CORNEAL ASTIGMATISM ANALYSIS AND VECTOR PLANNING TREATMENT

Номер: CA0002865322C
Принадлежит: ALPINS, NOEL AMI, ALPINS NOEL AMI

Techniques are disclosed in which a topographic parameter is determined in each hemidivision of the eye by considering the topography of reflected images from a multiplicity of illuminated concentric rings of the cornea. A simulated spherocylinder is produced to fit into each ring and conform to the topography thereof from which a topographic parameter for each ring can be obtained. All of the topographic parameters of each ring are combined and a mean summated value is obtained representing magnitude and meridian of each hemidivision. From these parameters, a single topographic value for the entire eye (CorT) can be found as well as a value representing topographic disparity (TD) between the two hemidivisions. The topography values for the hemidivisions are used in a vector planning system to obtain treatment parameters in a single step operation.

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02-09-1993 дата публикации

AUTOMATED LASER WORKSTATION FOR HIGH PRECISION SURGICAL AND INDUSTRIAL INTERVENTIONS

Номер: CA0002130999A1
Принадлежит:

... 2130999 9316631 PCTABS00025 A method, apparatus and system for template-controlled, precision laser interventions is described for microsurgery, and industrial micromachining. The system includes a user interface, wherein the user can either draw, adjust, or designate particular template patterns overlaid on live video images of the target and provides the means for converting the template pattern into a sequence of laser shots on the corresponding surgical or industrial site. The user interface also continuously presents three dimensional visual information to the surgeon/user during the operation. The system thus comprises the following key elements: (a) a user interface (19), consisting of a video display (18), microprocessor (16) and controls, (b) an imaging system (86), including a surgical video microscope with zoom capability, (c) an automated 3D target acquisition and tracking system (84, 85, 82) that can follow the movements of the tissue, during the operation, (d) a laser, (e) ...

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25-04-1996 дата публикации

EXCIMER LASER SYSTEM FOR CORRECTION OF VISION

Номер: CA0002202550A1
Принадлежит: BORDEN LADNER GERVAIS LLP

An apparatus and method for controlling an apparatus for removing tissue from the eye performs various types of corrections using a relatively large beam, but oscillating, or dithering, that being to prevent reinforcing ridges from being formed during the tissue removal process. Further, various types of correction, such as hyperopia and astigmatism correction, are performed using a large beam that is scanned over the area to be ablated using overlapping shots. Further, the epithelium in the area to be treated is removed using an infrared fluorescent dye to dye the epithelium, and then observing the fluorescent patterns from the epithelium area to be removed. Once a certain area is no longer fluorescent after laser shots, smaller shots are then applied, selectively removing the epithelium from the remaining regions. Again, the fluorescence patterns are observed, and the process is repeated until no epithelium remains. At this point, all of the epithelium is removed, and further a map is ...

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21-01-2004 дата публикации

尾加压素-Ⅱ激动剂和拮抗剂

Номер: CN0001469884A
Принадлежит:

... 本发明的公开了一类新的具有U-II拮抗剂和激动剂活性的多肽。本发明的特征还在于预防或治疗以尾加压素-II活性过度表达或低水平表达为特征的生理或心理疾病的方法。 ...

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22-03-2013 дата публикации

DEVICE AND PROCESS Of ASSISTANCE TO the TREATMENT OF the CORNEA

Номер: FR0002980095A1
Автор: HEHN FREDERIC
Принадлежит: HEHN

Un dispositif d'aide au traitement de la cornée comprend une mémoire (4), une interface (8) capable de recevoir et de mettre à disposition des données, ainsi qu'une unité de traitement (6) pour calculer et mettre à disposition à l'interface (8) une grandeur ophtalmologique utile au traitement de la cornée. Ce dispositif comprend en outre un ordonnanceur (10), agencé pour, à réception de données d'indice kératométrique central initial et des données de valeur d'asphéricité initiale à l'interface (8), stocker ces données dans la mémoire (4), appeler l'unité de traitement (6) avec lesdites données d'indice kératométrique central initial et de valeur d'asphéricité initiale ainsi qu'avec des données de valeur d'asphéricité cible, pour calculer un indice kératométrique périphérique, stocker les données correspondantes dans la mémoire (4) et les mettre à disposition à l'interface (8).

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15-02-2012 дата публикации

LASER VISION CORRECTION APPARATUS

Номер: KR1020120014066A
Автор:
Принадлежит:

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22-08-2013 дата публикации

DEVICE AND METHOD FOR LASERING THE HUMAN EYE

Номер: KR1020130093638A
Автор:
Принадлежит:

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01-11-2019 дата публикации

Systems and methods for ocular laser surgery and therapeutic treatments

Номер: TW0201941750A
Принадлежит:

Systems, devices and methods are provided to deliver microporation medical treatments to improve biomechanics, wherein the system includes a laser for generating a beam of laser radiation on a treatment-axis not aligned with a patient's visual-axis, operable for use in subsurface ablative medical treatments to create an array pattern of micropores that improves biomechanics. The array pattern of micropores is at least one of a radial pattern, a spiral pattern, a phyllotactic pattern, or an asymmetric pattern.

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06-01-2000 дата публикации

PATIENT FIXATION SYSTEM AND METHOD FOR LASER EYE SURGERY

Номер: WO2000000097A1
Принадлежит:

La présente invention concerne une amélioration de l'alignement entre l'oeil (E) et un faisceau laser (14) d'un système de chirurgie ophtalmologique par laser (10) mettant en oeuvre un système de fixation visuelle (38), lequel système de fixation (38) comporte souvent un train optique réglable (58). Le train optique (58) du système de fixation (38) fait qu'un oeil (E) affecté d'un défaut de réfraction caractérisé vient se focaliser avec précision sur la mire de fixation (60). Pour prendre en compte ce défaut de réfraction, le train optique réglable (58) projette systématiquement une image de la mire de façon que l'image projetée se trouve focalisée en avant ou en arrière du plan de l'oeil du patient (E). L'invention se rapporte également au calcul de la distance de projection convenant à la prise en compte de du défaut de réfraction de l'oeil (E). Ce calcul s'appuie en partie au moins sur la formule du verre correcteur de l'oeil considéré (E).

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13-11-2003 дата публикации

ABLATION METHOD USING LASER BEAM, AND DEVICE FOR ABLATION

Номер: WO0003092565A1
Принадлежит:

A method capable of easily assessing a state of ablation and accurately ablating work; and a device therefor. The method comprises the steps of irradiating a reference having a first curved surface shape approximating the curved surface shape of work with laser under determined conditions for laser radiation to form a second curved surface shape, measuring a third curved surface shape actually formed by laser radiation, and analyzing the change in the second curved surface shape on the basis of the third curved surface shape obtained. And, ablation data or control data on a laser radiating device is corrected on the basis of the results of analysis.

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15-09-1998 дата публикации

Method and apparatus for improving vision

Номер: US0005807381A1
Автор: Lieberman; David
Принадлежит: Scientific Optics, Inc.

Methods and apparatus are disclosed for causing the optical center of the eye to align "HIGH point" of the anterior surface of the cornea. In accordance with one aspect of the invention relating to corneal ablation procedures, the HIGH point of the eye is used as the pole of a spherical surface which is fitted approximately to a portion of the anterior surface of the cornea within a "bounded region." For corneal ablation procedures, the "bounded region" comprises a generally inverted-cup shaped region of the anterior surface of the eye bounded at its periphery by a plane which is substantially perpendicular to a local z-axis. During the operation local high points which project above the spherical surface are ablated. According to another aspect of the invention relating to radial keratotomy procedures, a pair of incisions in the plane of a "great circle" are formed in the cornea to weaken and flatten it. As used herein, a "great circle" is formed by a plane containing the HIGH point and ...

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20-08-2002 дата публикации

Controllable liquid crystal matrix mask particularly suited for performing ophthamological surgery, a laser system with said mask and a method of using the same

Номер: US0006436093B1
Принадлежит: RUIZ LUIS ANTONIO, MATALLANA EDUARDO

A system and method particularly suited for controlled ablation of the cornea, using ultraviolet laser radiation, with the cornea sculpturing action resulting from a computer driven digital programmed distribution of excimer flux density across a controllable liquid crystal matrix mask to achieve a desired volume and shape of ablation for the correction of the curvature of the cornea. The optical mask, in one embodiment, is based on an arrayable matrix of individual optical pixel cells with two optical states between fully transparent to fully opaque or mirror like to the UV light. The system provides a highly versatile system for correcting known corneal defects in both regular and irregular corneas by simply executing computer customized patterns in very short time and with great precision and detail.

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08-08-2013 дата публикации

System and method for ophthalmic surface based on objective quality estimation

Номер: US20130204237A1
Автор: Anatoly Fabrikant
Принадлежит: AMO DEVELOPMENT LLC

Systems and methods for measuring a topography of an optical tissue surface of an eye are provided by combining a measured elevation of the surface with a priori information of the surface to provide an estimate of mean and covariance of post-measurement orthogonal polynomial sequence amplitudes associated with the surface, determining a variance of elevation of the surface from the estimate, and constructing the topography from the estimate of mean and covariance of post-measurement amplitudes based on a comparison of the variance of elevation of the surface with a pre-determined threshold. The a priori information includes an estimate of mean and covariance of pre-measurement orthogonal polynomial sequence amplitudes associated with the surface.

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10-04-2014 дата публикации

Method and Systems for Laser Treatment of Presbyopia Using Offset Imaging

Номер: US20140100556A1
Принадлежит: AMO Manufacturing USA LLC

An ophthalmic surgery system and method for treating presbyopia by performing ablative photodecomposition of the corneal surface. The offset image of a variable aperture, such as a variable width slit and variable diameter iris diaphragm, is scanned in a preselected pattern to perform ablative sculpting of predetermined portions of a corneal surface. The scanning is performed to ablate an optical zone sized to match the patient pupil with a peripheral transition zone outside the pupil. The shape of the ablated optical zone is different from the shape of the final optical correction on the anterior surface of the cornea. The optical zone corrects for near-vision centrally and far-vision peripherally. A movable image displacement mechanism enables radial displacement and angular rotation of the profiled beam exiting from the variable aperture. The invention enables wide area treatment with a laser having a narrower beam than the treatment area, and can be used in the treatment of many conditions in conjunction with presbyopia such as hyperopia, hyperopic astigmatism and irregular refractive aberrations.

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01-01-2015 дата публикации

Ophthalmological Laser Treatment Device

Номер: US20150005752A1
Принадлежит:

An evaluating unit which is adapted to determine a degree of an instantaneous overlap between an optical zone of the eye and the structure, or at least a part of the structure effecting refractive correction, based on a recorded image. By determining the degree of overlap between the instantaneous optical zone and the structure to be introduced, it is possible to control the superposition of the optical zone with the tissue volume which is specifically altered by means of the laser cutting and, accordingly, to enable a maximum coverage. 1. An ophthalmological laser treatment device comprising:a femtosecond laser configured to introduce energy into a portion of an eye of a patient according to a predetermined surgical structure;a light source configured to illuminate at least the portion of the eye;a detection device configured to record an image of at least the portion of the eye;an evaluating unit which is configured to determine a degree of an instantaneous overlap between an optical zone of the eye and the predetermined surgical structure or at least a part of the predetermined surgical structure effecting refractive correction based on a recorded image; anda contact element for mechanically fixating the eye.2. The ophthalmological treatment device according to ;wherein the evaluating unit is configured to determine an area of a pupil based on the recorded image and an area of the predetermined surgical structure, or at least of the part of the predetermined surgical structure effecting refractive correction, and an intersection between the two areas.3. The ophthalmological treatment device according to ;wherein the evaluating unit is configured to identify and locate a characteristic of the eye in the recorded image and to determine a relative offset between a point of the characteristic and a point of the predetermined surgical structure.4. The ophthalmological treatment device according to ;wherein the evaluating unit displays the recorded image visually in ...

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12-01-2017 дата публикации

IMAGING SURGICAL TARGET TISSUE BY NONLINEAR SCANNING

Номер: US20170007447A1
Принадлежит:

Systems and techniques for laser surgery are described. Scan data may be created by determining a coordinate of the object at a set of points along an arc by the imaging system, wherein the coordinate of the object is a Z coordinate of an object layer. An object shape parameter and position parameter may be determined based on the scan data by a system control module by extracting an amplitude and a phase of the scan data determining a center of the object layer based on the extracted amplitude and phase. 1. A method for imaging an object , the method comprising the steps of:generating scan data by determining a coordinate of the object at a set of points along an arc by an imaging system, wherein the coordinate of the object is a Z coordinate of an object layer; and extracting an amplitude and a phase of the scan data; and', 'determining a center of the object layer based on the extracted amplitude and phase., 'determining an object shape parameter and an object position parameter based on the scan data by a system control module by'}2. The method of claim 1 , wherein:the object is a portion of a spherical surface layer; andthe determined object shape parameter is a radius of the spherical surface layer.3. The method of claim 1 , wherein:the object is an anterior lens surface layer of an eye;the object shape parameter is a radius of the anterior lens surface layer; andthe object position parameter is a coordinate of a center of the anterior lens surface.4. The method of claim 1 , wherein the determining the object position parameter step comprises:imaging the object with at least one of an optical coherence tomography (OCT) method, an ultrasound-based method, a microscopic method and an interference based method.5. The method of claim 1 , wherein the determining the object shape parameter and object position parameter step comprises:creating auxiliary scan data by determining a coordinate of the object at an auxiliary set of points along an auxiliary arc.6. The ...

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11-01-2018 дата публикации

RETINAL IMAGING FOR REFERENCE DURING LASER EYE SURGERY

Номер: US20180008460A1
Автор: Tanzer David J.
Принадлежит:

A method of laser eye surgery including linking retinal vessel architecture to corneal topography. This enables registration of the steep axis of the cornea in order to orient a toric intraocular lens, and/or to place astigmatic keratotomy incisions. First, a detailed pre-operative retinal image of the vasculature of the retina is obtained. In addition, a pre-operative image of the topography of the eye is obtained. The retinal image is then correlated or superimposed on the topography image to provide a reference. After the patient lies down under the laser eye surgery system, and during the surgery, the retinal vasculature is monitored which provides a reference to the surgery system about the topography of the eye. This process enables registration of the steep axis of the cornea in order to orient a toric intraocular lens and/or to place astigmatic keratotomy incisions. 1. A method of eye surgery on an astigmatic patient , comprising:pre-operatively obtaining a first retinal image of the retinal vessel architecture or optic nerve;pre-operatively scanning the corneal topography of the patient to obtain a scan;correlating the first retinal image and scan to determine retinal landmarks associated with an astigmatic axis of the patient;recording the location of the retinal landmarks in an optical system of an eye surgery system used for the eye surgery;positioning the patient supine on a chair configured for the eye surgery;obtaining a second retinal image of the retinal vessel architecture or optic nerve while the patient is positioned on the chair;analyzing the second retinal image to gauge a misalignment of the eye compared to the first retinal image;adjusting the patient or eye surgery system based on the misalignment and correlation of the first and second retinal images and scan; andperforming an eye surgery.2. The method of claim 1 , wherein the eye surgery is insertion of a toric intraocular lens claim 1 , and the step of recording includes placing a reticle ...

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11-01-2018 дата публикации

LENTICULAR LASER INCISION USING WAVEFRONT GUIDED MAPS

Номер: US20180008461A1
Принадлежит:

Embodiments generally relate to systems and methods for lenticular laser incisions based on wavefront maps. In an embodiment, a method comprises obtaining a wavefront map of a free eye using wavefront aberrometry to measure a refractive error, obtaining an iris image for the free eye using wavefront aberrometry, determining a free eye cutting profile to cut the cornea based on the wavefront measurement, determining a first translation of the free eye cutting profile based on estimated perturbation of the eye with a docking patient interface, docking the eye to a patient interface of an ultrashort pulsed laser system, obtaining an iris image for the docked eye, determining a second translation of the cutting profile for the docked eye from the free eye, using comparisons between the two iris images, and incising a bottom surface incision in the cornea based on the two translated cutting profiles. 1. A method of performing ophthalmic surgery , comprising:obtaining a wavefront map of a free eye using a wavefront aberrometer to measure a refractive error;obtaining an iris image of the free eye using the wavefront aberrometer;determining with a computer, comprising a processor and memory in communication with the wavefront aberrometer, a free eye cutting profile to cut in a cornea of the eye, based on the wavefront aberrometer measurement;determining with the computer, a first translation of the free eye cutting profile based on an estimated perturbation of the eye by a docking patient interface;docking the eye to the patient interface of an ultrashort pulsed laser system;obtaining an iris image of the docked eye by the ultrashort pulsed laser system;determining a second translation of the cutting profile for the docked eye from the free eye, by the computer, using the iris image for the docked eye compared to the iris image of the free eye; andincising, by the ultrashort pulsed laser system, a bottom surface incision in the cornea based on the first translation of the ...

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21-01-2016 дата публикации

METHOD AND SYSTEM FOR IMPROVING VISION OF AN EYE WITH MACULAR DEGENERATION

Номер: US20160015262A1
Принадлежит:

Methods and apparatus are disclosed for diagnosing vision and improving vision, for example by reducing or eliminating the effects of macular degeneration, in a manner which does not interfere with the natural shape of the cornea or its orientation relative to the remainder of the eye, but which changes its surface curvature appropriately to achieve the required correction of vision. The focus of sub-regions of the cornea is adjusted so that different regions focus at a controlled distance about a reference axis. This can be accomplished by shaping the cornea (e.g. through ablation) or by applying an appropriate contact lens or other optical lens.

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28-01-2016 дата публикации

Systems and Methods for Laser Beam Direct Measurement and Error Budget

Номер: US20160022492A1
Принадлежит:

Embodiments of the present invention generally describe systems, devices, and methods for directly measuring pulse profiles during pulse delivery. In some embodiment, the pulse profiles may be measured while the pulse is delivered to ablate a material. Embodiments, may calculate ablation spot parameters based on the pulse profiles and may refine one or more subsequent laser pulses based on deviations from the calculated ablation spot parameters from desired ablation spot parameters. In some embodiments, a fluence profiler is provided. The fluence profiler may measure a pulse profile of a laser pulse from a portion of the laser pulse. The fluence profiler may utilize a UV radiation energy sensor device and a camera-based imager. The measurements from the UV radiation energy sensor device and the camera-based imager may be combined and scaled to provide a measured pulse profile that corresponds to the delivered pulse. 1. A method comprising:generating a first laser pulse;delivering a portion of the first laser pulse to a beam profiler;delivering a remainder of the first laser pulse to a material;ablating the material at a treatment plane with the remainder of the first laser pulse to create an ablation spot;measuring a pulse profile of the first laser pulse with the beam profiler;calculating ablation parameters that correspond to the ablation spot based on the measured pulse profile;adjusting a delivery of a second laser pulse to the material based on the measured pulse profile of the first laser pulse.2. The method of claim 1 , wherein the material comprises a tissue of an eye claim 1 , and wherein the beam profiler comprises a beam splitter for directing a first part of the portion of the first laser pulse to a ultraviolet radiation energy sensor and a second part of the portion of the first laser pulse to a camera-based imager.3. The method of claim 2 , wherein the camera-based imager comprises a UV-to-visible converter plate claim 2 , an image sensor claim 2 , and ...

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02-02-2017 дата публикации

Apparatus for patterned plasma-mediated laser ophthalmic surgery

Номер: US20170027747A1
Принадлежит: Optimedica Corp

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

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01-02-2018 дата публикации

INTEGRATED OPHTHALMIC SURGICAL SYSTEM

Номер: US20180028355A1
Автор: Raksi Ferenc
Принадлежит:

An ophthalmic surgical system includes a chassis comprising a laser source. The system includes a gantry coupled to the chassis. The position of the gantry is adjustable. The system includes a reference interface coupled to the gantry. The reference interface comprises an attachment interface at a distal portion of the reference interface, configured to couple to a patient interface for docking with an eye. The reference interface is configured to move to a first plate position proximal to the chassis and a second plate position distal from the chassis. The system further includes an optical head unit coupled to the reference interface. The optical head unit comprises a laser scanner and a beam splitter. The optical head unit is configured to move to a first head unit position near a proximal end of the reference interface and a second head unit position which is a lockable surgical position near a distal end of the reference interface. 1. An ophthalmic laser surgical system , comprising:a chassis comprising a pulsed laser source configured to generate a laser beam of laser pulses;a gantry coupled to the chassis, wherein the position of the gantry with respect to the chassis is adjustable; the reference interface comprises an attachment interface configured to couple to a patient interface for docking with an eye, the attachment interface located at a distal portion of the reference interface; and', 'the reference interface is configured to move to a first reference interface position in which the attachment interface is proximal to the chassis and a second reference interface position in which the attachment interface is distal from the chassis;, 'a reference interface coupled to the gantry, wherein [ a laser scanner configured to scan the scan the laser beam of pulsed laser pulses to a target region of an eye docked to the patient interface; and', 'a beam splitter configured to multiplex the scanned laser beam of pulsed laser pulses with an imaging beam path of an ...

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17-02-2022 дата публикации

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Номер: US20220047419A1
Принадлежит:

A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors. 1. (canceled)2. A method for laser based surgical correction of an eyesight defect in a patient's eye , wherein the eye comprises a cornea having an anterior corneal surface and corneal tissue located below the anterior corneal surface , the method comprising:creating a three dimensional (3D) cut within the cornea, the 3D cut confining a volume located within the cornea, isolating the volume within the cornea, and making the volume removable from the interior of the cornea, wherein the volume is sized such that removal of the volume from the corneal tissue below the anterior corneal surface changes a shape of the anterior corneal surface such that the eyesight defect is corrected or reduced,wherein creating the 3D cut comprises emitting pulsed laser radiation from a laser device and focusing the pulsed laser radiation to a three-dimensional pattern of target points in the cornea, wherein the target points are located in a 3D surface defining the 3D cut,wherein creating the 3D cut further comprises forming the 3D surface with two surface parts including an anterior surface part and a posterior surface part, wherein one of these two surface parts is located at a constant distance to from ...

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05-02-2015 дата публикации

Method and Apparatus for Patterned Plasma-Mediated Laser Trephination of the Lens Capsule and Three Dimensional Phaco-Segmentation

Номер: US20150038952A1
Принадлежит:

System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist. 120-. (canceled)21. A laser surgical system for making incisions in ocular tissues during a cataract surgical procedure , the system comprising:a laser system comprising a scanning assembly, a laser operable to generate a laser beam configured to incise ocular tissue;an imaging device configured to acquire point by point image data from locations distributed throughout a volume of a crystalline lens of the patient and construct one or more images of the patient's eye tissues from the image data, wherein the one or more images comprise an image of at least a portion of the crystalline lens; and ["operate the imaging device to generate image data for patient's crystalline lens;", 'process the image data to identify a location for each of one or more targets in the lens of the patient;', 'process the image data to determine a treatment scanning pattern for scanning a focal zone of the laser beam for performing a treatment at each location of the one or more targets; and', 'operate the laser and the scanning assembly to scan the focal zone of the laser beam in the treatment scanning pattern at each location of the one or more targets, wherein positioning of the focal zone is guided by the control system based on the location of the one or more targets., 'a control system operably coupled to the laser system and configured to22. The system of claim 21 , wherein the control system is configured automatically identify each location of the one or more targets based on the detection of an edge in the ...

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24-02-2022 дата публикации

Apparatus for patterned plasma-mediated laser ophthalmic surgery

Номер: US20220054308A1
Принадлежит: AMO DEVELOPMENT LLC

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

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07-02-2019 дата публикации

Corneal Implant Systems and Methods

Номер: US20190038399A1
Автор: Muller David
Принадлежит:

According to one aspect of the present disclosure, an implant for correcting vision impairment is disclosed. The implant is made from a donor corneal tissue sized and shaped to provide a predetermined refractive correction and reshaping of a cornea. The donor corneal tissue includes a posterior surface and an anterior surface. The posterior surface has a surface profile that is configured to generally correspond to a shape of an implantation site of the cornea. 1receiving a donor corneal tissue, the donor corneal tissue including stromal tissue between an anterior surface and a posterior surface;cutting a plurality of lamellar sheets from the stromal tissue, wherein cuts are made between the posterior surface and the anterior surface and parallel to the posterior surface or the anterior surface to define surfaces of the lamellar sheets, and the lamellar sheets are defined by lamellar layers in the stromal tissue, parallel to the posterior surface or the anterior surface;cutting a plurality of lenticules from the lamellar sheets; andselecting at least one of the lenticules to be reshaped to form an implant having a shape and size configured for a predetermined refractive correction.. A method of making an implant for correcting vision impairment, comprising: This application is continuation of U.S. patent application Ser. No. 14/152,425, filed Jan. 10, 2014, which claims priority to and the benefit of U.S. Provisional Application No. 61/865,971, filed Aug. 14, 2013, U.S. Provisional Application No. 61/864,021, filed Aug. 9, 2013, U.S. Provisional Application No. 61/846,170, filed Jul. 15, 2013, and U.S. Provisional Application No. 61/786,115, filed Mar. 14, 2013, the contents of these applications being incorporated entirely herein by reference.The present invention relates generally to systems and methods for correcting vision, and more particularly, to systems and methods that employ eye implants to reshape the cornea in order to correct vision.Presbyopia is a ...

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03-03-2022 дата публикации

SYSTEMS AND METHODS FOR ALIGNING AN EYE WITH A PATIENT INTERFACE OF AN OPHTHALMIC LASER DEVICE

Номер: US20220062039A1
Принадлежит:

In certain embodiments, a system for aligning an eye with a patient interface of a laser device includes a camera, a display screen, and a computer. The camera records images of the eye through the patient interface of the laser device. A liquid is disposed between and is in contact with the patient interface and the outer surface of the eye. The images include an outline of the liquid. The display screen displays the images of the eye. The computer aligns the eye with the patient interface by: identifying the outline of the liquid in an image received from the camera; determining a misalignment of the eye according to the outline; and instructing the display screen to display a description of the misalignment. 1. A system for aligning an eye with a patient interface of a laser device , comprising:a camera configured to record a plurality of images of the eye through the patient interface of the laser device, a liquid disposed between the patient interface and an outer surface of the eye, the liquid in contact with the patient interface and with the outer surface of the eye, the images including an outline of the liquid;a display screen configured to display the images of the eye; and identifying the outline of the liquid in an image received from the camera;', 'determining a misalignment of the eye according to the outline; and', 'instructing the display screen to display a description of the misalignment., 'a computer configured to align the eye with the patient interface in order to align the eye with a laser beam of the laser device, the eye being aligned to perform a procedure on the eye according to a treatment pattern, the computer configured to align the eye with the patient interface by2. The system of claim 1 , the computer configured to determine the misalignment of the eye according to the outline by:identifying that a shape of the outline is an oval; anddetermining that an axis of the eye is at an angle to a z-axis of the laser device.3. The system of ...

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04-03-2021 дата публикации

Vision correction surgery recommendation method and device

Номер: US20210059521A1
Автор: Ik Hee Ryu, Jin Kuk Kim
Принадлежит: VISUWORKS

The present invention relates to a method for recommending a vision correction surgery, and the method according to one aspect of the present invention comprises: obtaining an examination data of a subject; predicting whether the vision correction surgery is suitable for the subject from the examination data; when the vision correction surgery is suitable for the subject, predicting whether the vision correction surgery using a laser is available for the subject from the examination data; when the vision correction surgery using the laser is available for the subject, calculating corneal shape factor prediction values of the subject after a standard vision correction surgery and a custom vision correction surgery from the examination data; and when the vision correction surgery using the laser is available for the subject, suggesting a vision correction surgery corresponding to the subject from the examination data.

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17-03-2016 дата публикации

LASER APPARATUS AND METHOD FOR REFRACTIVE SURGERY

Номер: US20160074225A1
Принадлежит:

An ultrashort pulsed laser instrument is used to perform refractive surgery. The invention operates in ablative and incisional modalities. In the ablative mode, spiral ablation disks () consisting of individual laser pulses () are produced at high scanning speeds. Ablation profile () may be produced in cornea () by stacking and arranging multiple ablation disks () to produce a specified shape change. Placement of ablation disks () is assisted by an optical tracking and control system that compensates for eye motion. A preferred embodiment allows for ablative corrections to be performed on non-planar posterior surface () of a laser cut flap affixed to registration platen (), thereby avoiding exposing the eye interior to high radiant power. Laser cut and contrast agent dyed fiduciary marks () may serve as reference features for the optical tracking system. Incisional procedures, such as corneal flaps for LASIK, may also be performed. 1. A laser instrument comprising:a. a laser source generating a laser pulse train of short duration pulses;b. an optical processing module configured to control and modulate said laser pulse train;c. a scanning beam delivery module for scanning in three dimensions the focal point of said laser pulse train;d. a focusing optics module for focusing said laser pulse train onto biological tissue for the purpose of removing said tissue;e. an optical tracking system for detecting relative lateral and axial motions between said laser pulse train and said tissue; andf. a means for adjusting and compensating the delivery of said laser pulse train to said tissue using said optical tracking system to correct for said lateral and axial motions.2. The laser instrument of claim 1 , wherein the instrument produces ablative tissue removal in a series of discrete ablative sequences.3. The laser instrument of claim 1 , wherein the scanning beam delivery module comprises optical scanning.elements operating with a linear scan rate of at least 0.5 meter/second ...

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17-03-2016 дата публикации

LASER APPARATUS AND METHOD FOR REFRACTIVE SURGERY

Номер: US20160074226A1
Принадлежит:

An ultrashort pulsed laser instrument is used to perform refractive surgery. The invention operates in ablative and incisional modalities. In the ablative mode, spiral ablation disks () consisting of individual laser pulses () are produced at high scanning speeds. Ablation profile () may be produced in cornea () by stacking and arranging multiple ablation disks () to produce a specified shape change. Placement of ablation disks () is assisted by an optical tracking and control system that compensates for eye motion. A preferred embodiment allows for ablative corrections to be performed on non-planar posterior surface () of a laser cut flap affixed to registration platen (), thereby avoiding exposing the eye interior to high radiant power. Laser cut and contrast agent dyed fiduciary marks () may serve as reference features for the optical tracking system. Incisional procedures, such as corneal flaps for LASIK, may also be performed. 1. A method for producing high optical contrast fiduciary marks in biologic tissue comprising the steps of:a. focusing short or ultrashort laser pulses on a cornea;b. scanning in a predetermined incisional pattern; andc. marking one or more incisions with the application of an optical contrast agent,wherein the fiduciary marks are advantageous for optical tracking and motion correction of targeted tissue.2. The method of claim 1 , further comprising the step of verifying proper fixation of a laser on a patient's eye prior to initiating the scanning.3. The method of claim 2 , wherein an optical means is used to verify the proper fixation of the laser.4. The method of claim 2 , wherein verifying proper fixation of the laser comprises visualizing the patient's eye and the fiduciary marks and using a user-interface to determine an appropriate offset value.5. The method of claim 1 , wherein a width and a depth of the one or more incisions is minimized to avoid interfering with visual acuity of a patient.6. The method of claim 5 , wherein the ...

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31-03-2022 дата публикации

METHOD FOR PROVIDING CONTROL DATA FOR AN EYE SURGICAL LASER OF A TREATMENT APPARATUS

Номер: US20220096273A1
Принадлежит:

The invention relates to a method for providing control data for an eye surgical laser () of a treatment apparatus () for removing tissue (). A control device () ascertains (S) a corneal geometry of a cornea () and an ocular wavefront () of a human or animal eye () from predetermined examination data. Further, a corneal wavefront () is ascertained (S) from the corneal geometry by means of a physical model, an internal wavefront () is calculated (S) from a difference of the ocular wavefront () and the corneal wavefront (), a wavefront () to be achieved is calculated (S) from a difference of a preset target wavefront () and the calculated internal wavefront (), a target corneal geometry () is ascertained (S) from the wavefront () to be achieved by means of the physical model, wherein the target corneal geometry (), which results in the wavefront () to be achieved upon a passage of the input wavefront () through a target cornea with the target corneal geometry (), is determined by means of the physical model, a tissue geometry to be removed is calculated (S) from a difference of the corneal geometry and the target corneal geometry (), and control data for controlling the eye surgical laser (), which includes the tissue geometry to be removed for removing the tissue, is provided (S). 1. A method for providing control data for an eye surgical laser of a treatment apparatus for removing tissue , wherein the method comprises the following steps performed by a control device:ascertaining a corneal geometry of a cornea of a human or animal eye from predetermined examination data;ascertaining a corneal wavefront from the corneal geometry using a physical model, wherein a change of an input wavefront upon a passage through the cornea with the ascertained corneal geometry is determined for ascertaining the corneal wavefront using the physical model;ascertaining an ocular wavefront of the human or animal eye from the predetermined examination data, wherein a change of the input ...

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26-03-2015 дата публикации

Operator-Controlled Scanning Laser Procedure Designed for Large-Area Epithelium Removal

Номер: US20150088104A1
Принадлежит: AMO DEVELOPMENT LLC

Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such penetration of the epithelial layer can be detected.

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21-03-2019 дата публикации

APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER OPHTHALMIC SURGERY

Номер: US20190083305A1
Принадлежит:

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions. 120.-. (canceled)21. An ophthalmic surgical system for treating a floater in an eye of a patient , comprising:a pulsed laser configured to produce a pulsed laser treatment beam which creates tissue breakdown in a focal zone of the pulsed laser treatment beam within the eye;an optical scanning system configured to position the focal zone of the laser treatment beam to a targeted location in three dimensions in the eye; andan imaging assembly configured to acquire image data from locations distributed throughout a volume adjacent a posterior pole of the eye, the imaging system comprising one or more selected from the group consisting of an interferometer, a time domain optical coherence tomography system, a frequency domain optical coherence tomography system, a confocal microscope, and a scanning confocal microscope system; operate the imaging system to acquire image data from locations distributed throughout the volume adjacent the posterior pole of the eye and construct one or more images of ocular tissue of the eye from the image data, wherein the one or more images comprise one or more boundaries of the floater in the ocular tissue;', 'construct a ...

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30-03-2017 дата публикации

Optical surface identification for laser eye surgery

Номер: US20170087019A1
Принадлежит: Optimedica Corp

Systems and methods automatically locate optical surfaces of an eye and automatically generate surface models of the optical surfaces. A method includes OCT scanning of an eye. Returning portions of a sample beam are processed to locate a point on the optical surface and first locations on the optical surface within a first radial distance of the point. A first surface model of the optical surface is generated based on the location of the point and the first locations. Returning portions of the sample beam are processed so as to detect second locations on the optical surface beyond the first radial distance and within a second radial distance from the point. A second surface model of the optical surface is generated based on the location of the point on the optical surface and the first and second locations on the optical surface.

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19-03-2020 дата публикации

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Номер: US20200085616A1
Принадлежит:

A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors. 1134122285 [{'b': 3', '3, 'comprises an interface (S) for supplying measurement data on parameters of the eye (), and defective-eyesight data on the eyesight defect to be corrected in the eye (),'}, {'b': 18', '18', '5, 'defines a volume () using supplied measurement and defective-eyesight data, which volume () is located within the cornea () and whose removal from the cornea causes the desired correction of defective eyesight,'}, {'b': 19', '20', '18', '5, 'determines a boundary surface (, ), which confines the defined volume () within the cornea (), and'}, {'b': 19', '20', '28', '5', '19', '20', '19', '20', '2', '18', '5, 'generates for said boundary surface (, ) a control dataset to control the laser device (L), which control dataset defines a three-dimensional pattern of the target points () in the cornea (), which are located in the boundary surface (, ) and are arranged such that the boundary surface (, ), after irradiation of the pulsed laser radiation () according to the control dataset, is provided as a cut surface which isolates the defined volume () in the cornea () and, thus, makes it removable.'}], 'wherein the planning device'}. A planning device for determining control ...

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19-03-2020 дата публикации

CALCULATION OF ACTUAL ASTIGMATISM CORRECTION AND NOMOGRAPHS FOR CORNEAL LASER TREATMENT

Номер: US20200085621A1
Автор: Lemonis Sissimos
Принадлежит:

A method for to calculation of actual astigmatism correction and nomographs for corneal laser treatment includes performing a post-operative measurement of the cornea of a patient to determine actual astigmatism coefficients. The actual astigmatism coefficients are compared against the expected astigmatism coefficients to generate a nomograph value or a nomograph curve over a sample population. The nomograph is used to calibrate subsequent laser treatments for improved accuracy of clinical results. 1. A method for calculating nomographs for corneal laser treatments , the method comprising:calculating an expected astigmatism coefficient for a patient subject to a first corneal laser treatment as a first difference between a pre-operative astigmatism coefficient and a correction astigmatism coefficient, wherein the pre-operative astigmatism coefficient represents a first measurement of a cornea of the patient before the first corneal laser treatment, and the correction astigmatism coefficient represents changes to the cornea planned for the first corneal laser treatment;receiving an indication that the first corneal laser treatment on the cornea of the patient was performed according to the correction astigmatism coefficient;receiving an actual astigmatism coefficient of the cornea of the patient, wherein the actual astigmatism coefficient represents a second measurement of the cornea after a time period after the first corneal laser treatment; andcalculating a nomograph value based on a second difference between the expected astigmatism coefficient and the actual astigmatism coefficient; andusing the nomograph value to calibrate the correction astigmatism coefficient for a subsequent corneal laser treatment on another patient, wherein the second difference for the subsequent corneal laser treatment on the other patient is smaller than the second difference for the first corneal laser treatment.2. The method of claim 1 , wherein the nomograph value is specific to a ...

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19-03-2020 дата публикации

CORNEAL TOPOGRAPHY MEASUREMENT AND ALIGNMENT OF CORNEAL SURGICAL PROCEDURES

Номер: US20200085622A1
Принадлежит:

Methods and apparatus are configures to measure an eye without contacting the eye with a patient interface, and these measurements are used to determine alignment and placement of the incisions when the patient interface contacts the eye. The pre-contact locations of one or more structures of the eye can be used to determine corresponding post-contact locations of the one or more optical structures of the eye when the patient interface has contacted the eye, such that the laser incisions are placed at locations that promote normal vision of the eye. The incisions are positioned in relation to the pre-contact optical structures of the eye, such as an astigmatic treatment axis, nodal points of the eye, and visual axis of the eye. 115-. (canceled)16. An apparatus for treating an eye having a cornea , the apparatus comprising:a topography measurement system for measuring a topography of the cornea of the eye; a patient interface for coupling to and retaining the eye; and', 'a processor comprising a tangible medium configured to determine a position of the eye, wherein the processor comprising the tangible medium is configured to determine one or more of a position or an orientation of the eye in response to the first image and the second image when the patient interface has been paced over the cornea., 'an image capture device for capturing an image of the eye, the image capture device configured to capture the first image of the eye when the cornea is exposed to a gas and a second image of the eye with the patient interface over the cornea;'}17. The apparatus of claim 16 , wherein the topography measurement system comprises one or more of a keratometry system claim 16 , an optical coherence tomography system claim 16 , a Placido disc topography system claim 16 , a Hartmann-Shack topography system claim 16 , a Scheimpflug image topography system claim 16 , a confocal tomography system claim 16 , or a low coherence reflectometry system.18. The apparatus of claim 16 , ...

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31-03-2016 дата публикации

METHODS AND SYSTEMS FOR CORNEAL TOPOGRAPHY, BLINK DETECTION AND LASER EYE SURGERY

Номер: US20160093063A1
Автор: Gonzalez Javier G.
Принадлежит:

A method of blink detection in a laser eye surgical system includes providing a topography measurement structure having a geometric marker. The method includes bringing the topography measurement structure into a position proximal to an eye such that light traveling from the geometric marker is capable of reflecting off a refractive structure of the eye of the patient, and also detecting the light reflected from the structure of the eye for a predetermined time period while the topography measurement structure is at the proximal position. The method further includes converting the light reflected from the surface of the eye into image data and analyzing the image data to determine whether light reflected from the geometric marker is present is in the reflected light, wherein if the geometric marker is determined not to be present, the patient is identified as having blinked during the predetermined time. 1. A method of blink detection in a laser eye surgical system , comprising:providing a topography measurement structure having at least one geometric marker;placing the topography measurement structure into a position proximal to an eye of a patient such that light traveling from the at least one geometric marker is capable of reflecting off a refractive structure of the eye of the patient;detecting the light reflected from the eye of the patient for a predetermined time period while the topography measurement structure is at the proximal position;converting the light reflected from the surface of the eye in the predetermined time period into image data; andanalyzing the image data to determine whether light corresponding to the geometric marker is detected in the reflected light, wherein if the geometric marker is determined not to be present, the patient is identified as having blinked during the predetermined time.2. The method of claim 1 , wherein the at least one geometric marker comprises a circle.3. The method of claim 1 , wherein there are a plurality of ...

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07-04-2016 дата публикации

CORNEAL TOPOGRAPHY MEASUREMENTS AND FIDUCIAL MARK INCISIONS IN LASER SURGICAL PROCEDURES

Номер: US20160095752A1
Принадлежит:

A method of cataract surgery in an eye of a patient includes identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography and forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye. A laser cataract surgery system a laser source, a topography measurement system, an integrated optical subsystem, and a processor in operable communication with the laser source, corneal topography subsystem and the integrated optical system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine one of an axis, meridian and structure of an eye of the patient based on the measurements received from topography measurement system, and direct the treatment beam so as to incise radial fiducial mark incisions. 1. A method of cataract surgery in an eye of a patient comprising:identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography;forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye.2. The method of claim 1 , wherein the feature is a meridian of the cornea.3. The method of claim 2 , wherein the meridian is the steepest meridian.4. The method of claim 1 , wherein the fiducial mark incisions are instrasomal corneal incisions.5. The method of claim 1 , wherein the fiducial mark incisions do not alter the optical properties of the eye.6. The method of claim 5 , wherein the length of each fiducial mark incision is less than 1.5 mm.7. The method of claim 1 , wherein identifying the feature comprises measuring the corneal topography with one or more of a keratometry system claim 1 , an optical coherence tomography system claim 1 , a Placido disc topography system claim 1 , a Hartmann-Shack topography system claim 1 , a Scheimpflug image ...

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12-04-2018 дата публикации

OPHTHALMIC LASER APPARATUS, SYSTEM, AND METHOD WITH HIGH RESOLUTION IMAGING

Номер: US20180098881A1
Принадлежит:

System and method of photoaltering a region of an eye using a high resolution digital image of the eye. The system includes a laser assembly for outputting a pulsed laser beam, an imaging system for capturing a real-time high resolution digital image of the eye and displaying the digital image of the eye, a user interface receiving at least one laser parameter input, and a controller coupled to the laser assembly, imaging system, and user interface. The controller directs the laser assembly to output the pulsed laser beam to the region of the eye based on the laser parameter input. 112-. (canceled)13. A system for photoaltering a region of an eye , the system comprising:a laser assembly configured to output a pulsed laser beam;an imaging system comprising:a digital camera;a first optical element configured to capture a first digital image of the eye with the digital camera, the first digital image of the eye having a first resolution;a second optical element configured to capture a second digital image of the eye with the digital camera, the second digital image of the eye having a second resolution; anda monitor configured to display a third digital image of the eye, the third digital image of the eye based on one of the first digital image of the eye and the second digital image of the eye; anda controller coupled to the laser assembly and the imaging system, the controller configured to:produce the third digital image of the eye; anddirect the laser assembly to output the pulsed laser beam to the region of the eye in response to at least one operator input, the at least one operator input based on the third digital image of the eye.14. (canceled)15. The system of claim 13 , wherein the laser assembly is configured to produce the pulsed laser beam with a pulse repetition rate of about 150 kHz.16. A kit for an ophthalmic laser system claim 13 , the ophthalmic laser system comprising an ocular microscope configured to view an eye claim 13 , the kit comprising:an ...

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21-04-2016 дата публикации

LASER EYE SURGERY LENS FRAGMENTATION

Номер: US20160106588A1
Принадлежит:

A laser eye surgery system includes a laser to generate a laser beam. A spatial measurement system generates a measurement beam and measure a spatial disposition of an eye. A processor is coupled to the laser and the spatial measurement system, the processor comprising a tangible medium embodying instructions to determine a spatial model of the eye in an eye coordinate reference system based on the measurement beam. The spatial model is mapped from the eye coordinate reference system to a machine coordinate reference system. A laser fragmentation pattern is determined based on a plurality of laser fragmentation parameters. The laser fragmentation pattern and the spatial model is rotated by a first rotation angle such that the spatial model is aligned with the reference axis of the machine coordinate reference system and the rotated laser fragmentation pattern is aligned with the corneal incision. 1. A laser eye surgery system , comprising:a laser to generate a laser beam;a spatial measurement system to generate a measurement beam and measure a spatial disposition of an eye; determine a spatial model of the eye in an eye coordinate reference system based on the measurement beam;', 'map the spatial model from the eye coordinate reference system to a machine coordinate reference system;', 'receive a rotation angle of a corneal incision relative to a reference axis of the machine coordinate reference system;', 'determine a laser fragmentation pattern based on a plurality of laser fragmentation parameters;', 'determine a first rotation angle based on the rotation angle of the corneal incision and a rotation angle of the laser fragmentation pattern relative to the reference axis of the machine coordinate reference system;', 'rotate the spatial model by a negative of the first rotation angle; and', 'rotate the laser fragmentation pattern and the spatial model by the first rotation angle such that the spatial model is aligned with the reference axis of the machine ...

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29-04-2021 дата публикации

DEVICE AND METHOD FOR PRODUCING CONTROL DATA FOR THE SURGICAL CORRECTION OF THE DEFECTIVE EYE VISION

Номер: US20210121323A1
Принадлежит:

A device for producing control data for a laser device for the surgical correction of defective vision. The device produces the control data such that the laser emits the laser radiation such that a volume in the cornea is isolated. The device calculates a radius of curvature R* to determine the control data, the cornea reduced by the volume having the radius of curvature R* and the radius of curvature being site-specific and satisfying the following equation: R*(r,φ)=1/((1/R(r,φ))+B(r,φ)/(n-1))+F, wherein R(r,φ) is the local radius of curvature of the cornea before the volume is removed, nis the refractive index of the material of the cornea, F is a coefficient, and B(r,φ) is the local change in refractive force required for the desired correction of defective vision in a plane lying in the vertex of the cornea, and at least two radii r1 and r2 satisfy the equation B(r=r1,φ)≠B(r=r2,φ). 134{'b': 2', '5', '3, 'the control data are adapted to control a laser (L) which cuts cornea tissue by irradiating laser radiation () into the cornea () of the eye (),'}{'b': 12', '2', '18', '5', '5, 'the device () generates the control data such that the laser (L), during operation according to the control data, emits the laser radiation () such that a volume () in the cornea () is isolated, the removal of which volume from the cornea () effects the desired correction of the defective vision and,'}{'b': 12', '5', '18, 'sub': 'CV', 'to determine the control data, the device () calculates a radius of curvature R* displayed by the cornea () reduced by the volume () characterized in that'}{'sub': 'CV', 'claim-text': {'br': None, 'i': R', 'V', 'r', 'R', 'r', 'B', 'r', 'n', 'F,, 'sub': C', 'CV', 'COR', 'c, '*(,φ)=1/((1/(,φ))+(,φ)/(-1))+'}, 'the radius of curvature R* is locally varying and satisfies the following equation{'sub': CV', 'c', 'COR, 'b': 5', '18', '5', '5, 'wherein R(r,φ) is the local radius of curvature of the cornea () before the volume () is removed, nis the refractive ...

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18-04-2019 дата публикации

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Номер: US20190110922A1
Принадлежит:

A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors. 1. (canceled)2. A treatment apparatus for ophthalmic surgery of an eye of a patient , said apparatus comprising:a laser device including a laser source emitting pulsed treatment laser radiation;a focusing device that focuses the treatment laser radiation to a focus position located in the eye;a scanner that shifts the focus position and a control device operably coupled to the scanner and configured to control the scanner by specifying a pattern of target points located within the eye such that a cut is generated within the eye,wherein the control device is further configured to introduce a point of aim in form of a pre-offset for at least some of the specified target points which point of aim differs from a desired final focus position by a spatial difference selected to compensate for focus position errors generated by the focusing device, andwherein the spatial difference depends on a position of a respective target point.3. The apparatus of claim 2 , wherein the control device is further configured to determine said spatial difference by accessing a correction table or function which indicates the focus position error as a function of the position of the respective target point.4. ...

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01-09-2022 дата публикации

CORNEAL TOPOGRAPHY MEASUREMENTS AND FIDUCIAL MARK INCISIONS IN LASER SURGICAL PROCEDURES

Номер: US20220273493A1
Принадлежит:

A method of cataract surgery in an eye of a patient includes identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography and forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye. A laser cataract surgery system a laser source, a topography measurement system, an integrated optical subsystem, and a processor in operable communication with the laser source, corneal topography subsystem and the integrated optical system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine one of an axis, meridian and structure of an eye of the patient based on the measurements received from topography measurement system, and direct the treatment beam so as to incise radial fiducial mark incisions. 13.-. (canceled)4. The method of claim 20 , wherein the fiducial mark incisions are intrastromal corneal incisions.5. (canceled)6. The method of claim 20 , wherein a length of each fiducial mark incision is less than 1.5 mm.7. The method of claim 20 , wherein the step of measuring topography or tomography of the eye comprises measuring a corneal topography with one or more of a keratometry system claim 20 , an optical coherence tomography system claim 20 , a Placido disc topography system claim 20 , a Hartmann-Shack topography system claim 20 , a Scheimpflug image topography system claim 20 , a confocal tomography system claim 20 , or a low coherence reflectometry system819.-. (canceled)20. A method of laser-assisted cataract surgery in an eye of a patient claim 20 , comprising:measuring a topography or tomography of the eye without a patient interface contacting the eye;placing a patient interface in contact with the eye;determining locations and incision profiles of one or more fiducial marker incisions with the patient interface contacting the eye based on the topography or ...

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21-05-2015 дата публикации

LASER EYE SURGERY SYSTEM CALIBRATION

Номер: US20150141972A1
Принадлежит:

A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part. 1. A laser system to treat an object with a laser beam , comprising:a laser to generate the laser beam;a tomography system to generate a measurement beam and measure an optically transmissive material of the object, the object being selected from the group consisting of an eye, a fluid of a patient interface above the eye, and a calibration apparatus comprising one or more structures similar to a structure of the eye;an optical delivery system coupled to the laser and the tomography system to deliver the laser beam and the measurement beam to the object; and measure a location for each of the one or more marks with the measurement beam, and', 'compare the corresponding target location with the measured location for each of the one or more marks in order to determine one or more of calibration or eye position., 'mark the eye at one or more locations corresponding to each of one or more target locations, the one or more locations comprising locations of one or more of a cornea, an aqueous humor, an iris, an anterior lens capsule, an anterior lens capsule, a posterior lens capsule, a cortex, or a nucleus and,'}, 'a processor coupled to the laser, the tomography system, and the optical delivery system, the processor comprising a ...

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28-05-2015 дата публикации

ADJUSTING LASER TREATMENT IN RESPONSE TO CHANGES IN THE EYE

Номер: US20150148788A1
Принадлежит:

According to certain embodiments, a system comprises one or more memories and one or more processors. The one or more memories store optical data from an optical recorder comprising at least two optical data sets by: receiving a first optical data set of an eye with a pupil having a first pupil size; and receiving a second optical data set of the eye with the pupil having a second pupil size. The one or more processors determine a pseudo-rotation related to a pupil size change, receive a measured cyclotorsion, calculate an actual cyclotorsion from the measured cyclotorsion and the pseudo-rotation, and adjust a laser treatment according to the actual cyclotorsion. 1. A method comprising: gathering a first optical data set of an eye with a pupil having a first pupil size; and', 'gathering a second optical data set of the eye with the pupil having a second pupil size;, 'storing, by one or more memories, optical data from an optical recorder comprising at least two optical data sets bydetermining, by one or more processors, a pseudo-rotation related to a pupil size change;receiving, by the one or more processors, a measured cyclotorsion;calculating, by the one or more processors, an actual cyclotorsion from the measured cyclotorsion and the pseudo-rotation; andadjusting, by the one or more processors, a laser treatment according to the actual cyclotorsion.2. The method of claim 1 , the calculating the actual cyclotorsion from the measured cyclotorsion and the pseudo-rotation further comprising:subtracting the pseudo-rotation from the measured cyclotorsion.3. The method of claim 1 , the determining the pseudo-rotation related to the pupil size change further comprising:determining a first coordinate set indicating a first location of a feature of the eye from the first optical data set;determining a second coordinate set indicating a second location of the feature of the eye from the first second data;calculating a coordinate difference between the first coordinate set ...

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24-06-2021 дата публикации

POST-TREATMENT IN REFRACTION CORRECTION DURING EYE SURGERY

Номер: US20210186759A1
Принадлежит: CARL ZEISS MEDITEC AG

A planning device for generating control data, a treatment apparatus for refraction correction eye surgery and a method for generating control data for such a treatment apparatus which allows an improved subsequent refraction correction. The planning device includes a calculation processor for defining a cut surface of the cornea for post-treatment, wherein the calculation device is designed such that a change of thickness of the epithelium is taken into account in the calculation, which was caused essentially by a pretreatment. 110.-. (canceled)11. A planning device for generating control data for a treatment device for eye surgery , which generates at least one incision in a cornea by application of a laser device , the planning device comprising:a calculating processor that determines the at least one incision in the cornea selected from a group consisting of a cap incision, a lenticule incision, an access incision and a combination of the foregoing,wherein the calculating processor determines the at least one incision in the cornea based on data of a refraction correction, and generates a control data set for actuating the laser device for the at least one incision in the cornea,wherein the planning device is configured such that a change in thickness of a corneal epithelium is taken into account in planning.12. The planning device for generating control data for a treatment device according to claim 11 , wherein the data for a refraction correction also include data from a prior treatment.13. The planning device for generating control data for a treatment device according to claim 11 , wherein the change in thickness comprises a thickening caused substantially by a prior treatment.14. A treatment device for eye surgery claim 11 , comprising:a laser device, which generates the at least one incision in the cornea by application of a laser beam in accordance with control data, and{'b': '1', 'the planning device for generating control data as claimed in claim .'}15 ...

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29-09-2022 дата публикации

APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER OPHTHALMIC SURGERY

Номер: US20220304854A1
Принадлежит:

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions. 120.-. (canceled)21. An ophthalmic surgical system for treating a floater in an eye of a patient , comprising:a pulsed laser configured to produce a pulsed laser treatment beam which creates tissue breakdown in a focal zone of the laser treatment beam within the eye;an optical scanning system configured to position the focal zone of the laser treatment beam to a targeted location in three dimensions in the eye; andan optical coherence tomography (OCT) imaging system configured to acquire image data from locations distributed throughout a volume adjacent a posterior pole of the eye; operate the OCT imaging system to acquire OCT image data from locations distributed throughout the volume adjacent the posterior pole of the eye;', 'process the image data to identify one or more boundaries of the floater in an ocular tissue of the eye and to generate a treatment cutting region based on the boundaries of the floater; and', 'operate the laser and the optical scanning system to direct the pulsed treatment beam in a pattern based on the treatment cutting region to dissect the ocular tissue, including to guide a positioning of the treatment beam focal zone in the ...

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11-09-2014 дата публикации

Methods And Apparatus For Improved Post-Operative Ocular Optical Performance

Номер: US20140257258A1
Автор: Kurtz Ronald M.
Принадлежит: ALCON LENSX, INC.

Techniques, systems are described for performing laser eye surgery. In one aspect, a method for improving an optical function of an eye includes preparing the eye for surgery by determining an optical characteristic of the eye. Laser marking pulses are applied to generate a laser mark in a region of the eye in relation to the determined optical characteristic. Also, a surgical procedure is performed in a surgical region selected in relation to the generated laser mark.

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13-06-2019 дата публикации

DEVICE FOR SURGICALLY CORRECTING AMETROPIA OF AN EYE AND METHOD FOR CREATING CONTROL DATA THEREFOR

Номер: US20190175281A1
Принадлежит: CARL ZEISS MEDITEC AG

A device and a method for producing control data, which are designed to control a laser machining device to surgically correct ametropia of an eye in which, in order to define a space in the cornea, defines a front cutting surface, a rear cutting surface and an edge section, which are to be produced as cutting surfaces in the cornea. The rear cutting surface has a non-circular, oval edge lying in a plane, the edge section connecting the edge to the front cutting surface and the edge section being designed as a non-rotationally symmetrical cylinder or truncated cone, the base of which is the edge. 115.-. (canceled)16. A method for producing control data configured to control a laser processing apparatus for refractive error correction of an eye by surgery , comprising:generating the control data to define an anterior cut surface, a posterior cut surface and a side cut in the cornea that enclose a volume in the cornea, whereinthe posterior cut surface comprises a non-circular, oval edge, which lies in a plane,the side cut connects the edge to the anterior cut surface andthe side cut is embodied as a lateral surface of a non-rotationally symmetric cylinder or conical frustum, the directrix of which is the edge.17. The method as claimed in claim 16 , further comprising generating the control data to define the posterior cut surface to comprise an elliptical edge.18. The method as claimed in claim 16 , further comprising generating the control data to define the anterior cut surface to have a circumference which claim 16 , in terms of form claim 16 , corresponds to the edge and the side cut to connect the posterior cut surface to the circumference of the anterior cut surface.19. The method as claimed in claim 18 , further comprising generating the control data to define the anterior cut surface to be spherically curved and the circumference to not lie in a plane.20. The method as claimed in claim 18 , further comprising generating the control data to define the anterior ...

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09-07-2015 дата публикации

METHOD FOR SCANNING A PULSED LASER BEAM

Номер: US20150190282A1
Принадлежит:

Methods of photoaltering a region of a material using a pulsed laser beam. The method includes scanning the pulsed laser beam in a first portion of the region with a first pattern, scanning the pulsed laser beam in a second portion of the region with a second pattern, and separating a flap of the material at the region. The system includes a laser, a controller selecting at least first and second patterns, and a scanner operable in response to the controller. The first pattern has a first maximum acceleration associated with the second portion, and the second pattern has a second maximum acceleration associated with the second portion. The second maximum acceleration is less than the first maximum acceleration. The scanner scans the pulsed laser beam from the laser in the first portion with the first pattern and in the second portion with the second pattern. 1. A method of photoaltering a sub-surface region of a patient's cornea using a pulsed laser beam , the sub-surface region having a first portion and a second portion smaller than and located within the first portion , the method comprising the steps of:transmitting the pulsed laser beam with a scanner to the first portion of the region in accordance with only a first laser scan pattern based on a continuous scan of the pulsed laser beam, the first laser scan pattern continuing until an acceleration associated with scanning the first laser scan pattern reaches a pre-determined maximum limit; andafter the first laser scan pattern reaches the pre-determined maximum limit of the acceleration associated therewith, transmitting the pulsed laser beam with a scanner to the second portion of the region in accordance with a second laser scan pattern based on a continuous scan of the pulsed laser beam and that is different than the first laser scan pattern, the second laser scan pattern having an associated acceleration that is less than the pre-determined maximum limit, and wherein the first portion and the second ...

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06-07-2017 дата публикации

TOPOGRAPHY MODULE FOR OPTHALMOLOGICAL DEVICES WITH A DISTANCE-INDEPENDENT KERATOMETER AND METHOD FOR THE USE THEREOF

Номер: US20170188821A1
Автор: Fuchs Rico, Reich Matthias
Принадлежит: CARL ZEISS MEDITEC AG

A module for ophthalmological devices which enables ophthalmological devices to carry out keratometry and topography measurements of the eye. The proposed topography module is provided for ophthalmological devices with a distance-independent keratometer. The topography module, which is used to generate the luminous pattern, is arranged in a fixed or moveable manner in the beam path between the ophthalmological device and the eye. A control unit is provided to control the topography module for generating luminous patterns. The provided evaluation unit is also suitable to carry out keratometric as well as topographic evaluations of the reflection images of an eye, captured and transmitted by the detection unit. The invention enables ophthalmological devices, which are equipped with a distance-independent keratometer, to carry out additional topographical measurements on the eye. 121-. (canceled)22. A topography module for ophthalmological devices that have a distance-independent keratometry measurement device having a detection beam path including elements for distance independent keratometry measurement , elements for illumination and detection , as well as elements for control and evaluation , wherein:the topography module generates a luminous pattern, andthe topography module is disposed, in a stationary or moveable manner, in a beam path between the ophthalmological device, and the eye,wherein the topography module transmit a keratometry beam, andincludes devices that facilitate placement of the topography module at a definite position in the beam path between the ophthalmological device and the eye,wherein an existing control unit of the ophthalmological device is adapted for controlling the topography module appropriately for generating light patterns, andwherein an existing evaluation unit is suitable for evaluating the reflected images of an eye recorded and transmitted by the detection unit in both a keratometric as well as topographic manner.22. The ...

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20-06-2019 дата публикации

OPTICAL MEASUREMENT SYSTEMS AND PROCESSES WITH WAVEFRONT ABERROMETER HAVING VARIABLE FOCAL LENGTH LENS

Номер: US20190183337A1
Принадлежит:

An optical measurement system: passes a probe light beam through a variable focal length lens to the retina of an eye, and returns light from the retina through the variable focal length lens to a wavefront sensor; adjusts the focal length of the variable focal length lens to provide a desired characteristic to at least one of: the probe light beam, and the light returned by the retina to the wavefront sensor; passes a calibration light through the variable focal length lens to the wavefront sensor while the variable focal length lens is at the adjusted focal length to ascertain the adjusted focal length; and makes a wavefront measurement of the eye from the light returned from the retina of the eye through the variable focal length lens to the wavefront sensor, and from the adjusted focal length ascertained from the calibration light received by the wavefront sensor. 124-. (canceled)25. A system , comprising:a variable focal length lens;a processor configured to adjust a focal length of the variable focal length lens;a switchable calibration light source disposed at a known distance from the variable focal length lens and configured to provide a calibration light beam to the variable focal length lens; anda wavefront sensor configured to receive the calibration light beam from the variable focal length lens when the switchable calibration light source is on, and in response thereto to output image data,wherein the processor is configured to receive the image data, andwherein the processor is further configured to control the switchable calibration light source to be on and to adjust the focal length of the variable focal length lens to have an adjusted focal length, and to ascertain the adjusted focal length of the variable focal length lens from the image data output from the wavefront sensor in response to the calibration light beam received by the wavefront sensor from switchable calibration light source.26. The system of claim 25 , wherein the wavefront sensor ...

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12-07-2018 дата публикации

Laser Induced Collagen Crosslinking in Tissue

Номер: US20180193188A1

The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage or cornea, without using a photosensitizer (e.g., riboflavin), by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of tissue. In an embodiment, the femtosecond laser operates in the infrared frequency range. 1. A method of reshaping curvature of a region of a cornea having an initial curvature , the method comprising:inducing partial ionization in a region of the cornea by applying laser light energy below optical breakdown, wherein a majority of the laser light is in wavelengths, or integral fractions thereof, that are not absorbed directly by amino acids in collagen of the cornea.2. The method of claim 1 , further comprising:projecting an illumination pattern on the cornea;recording a pattern of reflection from the cornea with a camera; andconverting the pattern of reflection into a topography of the cornea.3. The method of claim 1 , wherein the laser light energy is applied in an illumination pattern generated by a continuous wave laser.4. The method of claim 1 , wherein the initial curvature is reshaped to a curvature corresponding to a desired topography.5. The method of claim 1 , wherein the region of the cornea to be modified is based at least in part on a deformation map.6. The method of claim 1 , wherein the inducing partial ionization comprises scanning a laser over the region of the cornea to be modified.7. The method of claim 6 , wherein the scanning comprises scanning a femtosecond laser.8. The method of claim 6 , wherein the scanning comprises scanning a femtosecond laser having an average power output from about 10 mW to about 100 mW.9. The method of claim 6 , wherein the scanning comprises scanning a femtosecond laser having ...

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25-09-2014 дата публикации

Ophthalmic Laser System and Method for Severing Eye Tissue

Номер: US20140288539A1
Принадлежит: CARL ZEISS MEDITEC AG

An ophthalmic laser device with a treatment beam path that includes a variably adjustable modulator. The ophthalmic laser device is adapted to determine for the radiation pulses to be inputted into the tissue a power density to be inputted into the relevant target volume through the treatment beam path depending on a spatial distance between two target volumes of immediately successive radiation pulses and to adjust the modulator parallel in time with the control of the deflecting unit such that the relevant pulse in the target volume has the determined power density. 1. An ophthalmic laser device for severing eye tissue , comprising:an ultrashort pulse laser configured to focus radiation pulses in different target volumes along a treatment beam path;a variably adjustable beam deflecting unit;focusing optics;a control unit configured to control the laser and configured to control the deflecting unit during an emission of a sequence of radiation pulses; andvariably adjustable modulator;wherein the variably adjustable beam deflecting unit, the focusing optics, and the variably adjustable modulator are arranged along the treatment beam path;{'sub': i', 's, 'wherein the control unit is configured to determine for a radiation pulse, or for every radiation pulse of the sequence, a power density (E) to be inputted into the relevant target volume through the treatment beam path depending on a spatial distance dbetween two target volumes of immediately successive radiation pulses; and'}{'sub': 'i', 'wherein the control unit is configured to adjust the modulator parallel in time with the control of the deflecting unit such that the relevant pulse in the target volume has the determined power density (E).'}2. The laser device according to ;{'sub': 't', 'wherein the power density to be inputted depends in a mathematically monotonically increasing manner on the spatial distance d.'}3. The laser device according to ;wherein the control unit controls the deflecting unit during ...

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26-07-2018 дата публикации

LASER EYE SURGERY SYSTEM CALIBRATION

Номер: US20180207031A1
Принадлежит:

A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part. 124.-. (canceled)25. A method for treating an eye with a laser beam , comprising:providing a laser configured to generating the laser beam;providing a tomography system configured to generate a measurement beam and measure at least one surface of a structure of the eye;providing an optical delivery system coupled to the laser and the tomography system configured to deliver the laser beam and the measurement beam to the eye; andstoring in a memory a look-up table, the look-up table including first data which maps locations within the eye to one or more control parameters for the laser, and further including second data which maps the locations within the eye to one or more control parameters for the tomography system;by a processor coupled to the memory, in response to the first data in the look-up table, controlling the laser and the optical delivery system to deliver the laser beam to the eye to mark the eye at one or more mark locations corresponding to each of one or more target locations, the one or more target locations being disposed at one or more of a cornea, an aqueous humor, an iris, an anterior lens capsule, an anterior lens capsule, a posterior lens capsule, a cortex, or a nucleus;by the processor, in response to the ...

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11-08-2016 дата публикации

CLOSED-LOOP LASER EYE SURGERY TREATMENT

Номер: US20160228296A1
Принадлежит:

A laser eye surgery system includes a laser to generate a laser beam. A topography measurement system measures corneal topography. A processor is coupled to the laser and the topography measurement system, the processor embodying instructions to measure a first corneal topography of the eye. A first curvature of the cornea is determined. A target curvature of the cornea that treats the eye is determined. A first set of incisions and a set of partial incisions in the cornea smaller than the first set of incisions are determined. The set of partial incisions is incised on the cornea by the laser beam. A second corneal topography is measured. A second curvature of the cornea is determined. The second curvature is determined to differ from the target curvature and a second set of incisions are determined. The second set of incisions is incised on the cornea. 1. A method of treating an eye , comprising:measuring a first corneal topography of the eye;determining a first curvature of the cornea based on the first corneal topography, and a target curvature of the cornea that treats the eye;determining a first set of incisions in the cornea to achieve the target curvature in the cornea and a set of partial incisions in the cornea smaller than the first set of incisions;performing the set of partial incisions on the cornea by a laser;measuring a second corneal topography after performing the set of partial incisions;determining a second curvature of the cornea on the basis of the second corneal topography;determining that the second curvature differs from the target curvature;determining a second set of incisions in the cornea different from the first set of incisions to achieve the target curvature in the cornea; andperforming the second set of incisions on the cornea by the laser.2. The method of claim 1 , further comprising:measuring a third corneal topography after performing the second set of incisions;determining a third curvature of the cornea on the basis of the third ...

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09-08-2018 дата публикации

Laser Induced Collagen Crosslinking in Tissue

Номер: US20180221201A1

The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage or cornea, without using a photosensitizer (e.g., riboflavin), by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of tissue. In an embodiment, the femtosecond laser operates in the infrared frequency range. 1. A method of inducing cross-linking in a tissue containing water , comprising:generating reactive oxygen species by ionizing water molecules, the ionizing including focusing light on a tissue containing water;the focusing and intensity of the light being sufficient to cause ionization of water without causing optical breakdown of molecules of the tissue;the range of frequencies of said light being selected to excite water molecules without directly forming covalent bonds.2. The method of claim 1 , whereinthe tissue is a cornea, andthe focusing includes projecting an illumination pattern on the cornea.3. The method of claim 1 , wherein the focusing includes scanning a laser over a region of a cornea to be modified.4. The method of claim 3 , wherein the scanning includes scanning a femtosecond laser.5. The method of claim 4 , wherein the scanning includes scanning a femtosecond laser having an average power output from about 10 to about 100 mW.6. The method of claim 5 , wherein the scanning includes scanning a femtosecond laser having a pulse energy of from about 0.1 nJ to about 10 nJ.7. The method of claim 4 , scanning includes scanning in a pattern of exposure comprising a circle claim 4 , annulus claim 4 , and/or ellipse.8. The method of claim 4 , wherein the scanning includes scanning in multiple layers of the cornea.9. A method of inducing cross-linking in a tissue containing water claim 4 , comprising:generating reactive oxygen ...

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23-10-2014 дата публикации

Method and Apparatus for Patterned Plasma-Mediated Laser Trephination of the Lens Capsule and Three Dimensional Phaco- Segmentation

Номер: US20140316386A1
Принадлежит:

System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye issue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist. 124-. (canceled)25. A method for incising ocular tissue during a cataract surgical procedure , the method comprising:operating an imaging device to acquire image data of ocular tissue, the image data including lens interior image data for an interior portion of the lens of a patient's eye;processing the image data via a control system so as to generate an anterior capsulotomy scanning pattern for scanning a focal zone of a laser beam for performing an anterior capsulotomy, the imaging device being operatively coupled to the control system;generating the laser beam; andscanning the focal zone of the laser beam in the anterior capsulotomy scanning pattern so as to perform the anterior capsulotomy, wherein positioning of the focal zone is controlled by the control system based on the image data.26. The method of claim 25 , wherein the laser beam has a wavelength between 800 nm and 1 claim 25 ,100 nm claim 25 , the laser beam comprises pulses having pulse energy between 1.0 micro joules and 1 claim 25 ,000 micro joules claim 25 , the laser beam comprises pulses having a pulse duration between about 100 femtoseconds and about 10 picoseconds claim 25 , and the laser beam comprises pulses having a repetition rate between 1 kHz and about 200 kHz.27. The method of claim 25 , wherein scanning the focal zone of the laser in the anterior capsulotomy scanning pattern includes sequentially applying laser pulses to different depths claim 25 , wherein the laser pulses are first applied at a maximum depth and then ...

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23-10-2014 дата публикации

Methods and Systems for Tracking a Torsional Orientation and Position of an Eye

Номер: US20140316390A1
Автор: Chernyak Dimitri
Принадлежит: AMO Manufacturing USA, LLC

Methods and systems for tracking a position and torsional orientation of a patient's eye. In one embodiment, the present invention provides methods and software for registering a first image of an eye with a second image of an eye. In another embodiment, the present invention provides methods and software for tracking a torsional movement of the eye. In a particular usage, the present invention tracks the torsional cyclorotation and translational movement of a patient's eye so as to improve the delivery of a laser energy to the patient's cornea. 1. A method for performing a laser in situ keratomileusis (LASIK) procedure , the method comprising:obtaining a first image of the eye;processing the first image of the eye so as to identify an iris image;processing the first iris image so as to identify a plurality of natural tissue markers separated across the iris image;obtaining a second image of the eye while the eye is aligned with a femtosecond laser;identifying at least some of the plurality of markers within the second image of the eye;determining a rotational offset between the first image of the eye and the second image of the eye using the identified markers; anddirecting a femtosecond laser toward the eye per the rotational offset so as to perform the LASIK procedure.2. A system comprising:an image capture device; processing the first image of the eye so as to identify an iris image;', 'processing the first iris image so as to identify a plurality of natural tissue markers separated across the iris image; and', 'processing the second image of the eye so as to identify at least some of the plurality of markers within the second image., 'a processor coupled to the image capture device so as to receive a first image of an eye, the processor having a memory for receiving a second image of the eye and software comprising a tangible media embodying machine-readable instructions for3. A system for performing a laser in situ keratomileusis (LASIK) procedure , the system ...

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19-08-2021 дата публикации

CLOSED-LOOP LASER EYE SURGERY TREATMENT

Номер: US20210251807A1
Принадлежит:

A laser eye surgery system includes a laser to generate a laser beam. A topography measurement system measures corneal topography. A processor is coupled to the laser and the topography measurement system, the processor embodying instructions to measure a first corneal topography of the eye, A first curvature of the cornea is determined. A target curvature of the cornea that treats the eye is determined. A first set of incisions and a set of partial incisions in the cornea smaller than the first set of incisions are determined. The set of partial incisions is incised on the cornea by the laser beam. A second corneal topography is measured. A second curvature of the cornea is determined. The second curvature is determined to differ from the target curvature and a second set of incisions are determined. The second set of incisions is incised on the cornea. 120.-. (canceled)21. A method of treating an eye , comprising:measuring a first corneal topography of the eye;determining a first curvature of the cornea based on the first corneal topography, and determining a target curvature of the cornea that treats the eye;determining a first set of incisions in the cornea to achieve the target curvature of the cornea;determining a first set of first partial incisions in the cornea, wherein the first partial incisions are smaller than the incisions of the first set of incisions;performing the first set of first partial incisions on the cornea by a laser;measuring a second corneal topography after performing the first set of first partial incisions;determining a second curvature of the cornea based on the second corneal topography;determining whether the second curvature differs from the target curvature by more than a threshold which indicates that the second curvature matches the target curvature;when it is determined that the second curvature and the target curvature do not differ by more than the threshold, then ending treatment of the eye; and determining a second set of ...

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03-09-2015 дата публикации

LASER ASSISTED CATARACT SURGERY

Номер: US20150245945A1
Автор: Mordaunt David
Принадлежит:

Laser assisted cataract surgery methods and devices utilizing one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may optionally be added onto or into the lens capsule tissue, and the treatment laser wavelength selected to be strongly absorbed by the light absorbing agent. Alternatively, the treatment laser wavelength may be selected to be absorbed or strongly absorbed by the tissue itself, in which case no additional light absorbing agent need be used. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the procedure. The devices may be attached to or integrated with microscopes. 1. A device for creating an opening in the anterior lens capsule of the eye , the device comprising:a treatment laser beam;a two-dimensional scanner on which the treatment laser beam is incident, the scanner having a programmed scan profile for a predetermined treatment pattern in which the treatment laser beam is scanned to form a closed curve at the anterior lens capsule;a lens positioned to focus the treatment laser beam to a waist at the anterior lens capsule, the treatment laser beam expanding from its waist to be defocused on the retina of the eye;a first visible light visualization laser beam sharing an optical path with the treatment laser beam; anda second visible light visualization laser beam intersecting the first visualization laser beam at or approximately at the waist of the treatment laser beam;wherein the treatment laser beam has a wavelength selected to be strongly absorbed at the anterior lens capsule and a power selected to cause thermal denaturing of collagen in the anterior lens capsule resulting in thermal tissue separation along the closed curve of the treatment pattern without ablating anterior lens capsule tissue.2. The device of claim 1 , wherein the first visualization laser ...

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03-09-2015 дата публикации

TECHNIQUE FOR TREATING PRESBYOPIA

Номер: US20150245948A1
Принадлежит:

A system and method for reshaping a cornea of a patient's eye to treat presbyopia are disclosed as well as a method of generating a computer program for use in such system. Ray tracing is used to determine an ablation pattern that defines an amount of corneal tissue to be ablated, wherein the ablation pattern achieves a pre-defined amount of at least one of sphere, spherical aberration, coma, and astigmatism in the eye. 1. A method of determining a corneal ablation pattern for treating presbyopia of a human eye , comprising:defining a non-zero amount of induced aberration for a presbyopic human eye; andapplying a ray tracing process to determine a corneal ablation pattern defining an amount of corneal tissue that, when removed from the eye, leaves the eye with the defined amount of induced aberration.2. The method of claim 1 , wherein the induced aberration includes an aberration selected from a group consisting of sphere claim 1 , spherical aberration claim 1 , coma claim 1 , astigmatism claim 1 , or a combination of at least two aberrations.3. The method of claim 2 , wherein the induced aberration further includes a higher-order aberration.4. The method of claim 1 , wherein the ray tracing process is performed using measurement data for one or more of the following: pre-operative refraction of the eye claim 1 , pre-operative aberrations of the eye claim 1 , corneal topography of the eye claim 1 , one or more opto-geometrical parameters of the eye claim 1 , one or more pupil-related parameters.5. The method of claim 1 , wherein the induced aberration is effective to increase a depth of focus of the eye by about 1 to 3 diopters.6. A method of treating presbyopia of a human eye claim 1 , comprising:defining a non-zero amount of induced aberration for the eye;applying a ray tracing process to determine a corneal ablation pattern defining an amount of corneal tissue that, when removed from the eye, leaves the eye with the defined amount of induced aberration; andmoving ...

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23-08-2018 дата публикации

CONTROLLED CROSS-LINKING INITIATION AND CORNEAL TOPOGRAPHY FEEDBACK SYSTEMS FOR DIRECTING CROSS-LINKING

Номер: US20180235808A1
Принадлежит:

Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye. Methods of activating cross-linking according to information provided by a feedback system in order to improve accuracy and safety of a cross-linking therapy are also provided. 142-. (canceled)43. A method for treating an eye , comprising:obtaining one or more measurements of an eye of a subject;determining, based on the one or more measurements of the eye, an assessment of an initial shape of a cornea of the eye;determining, based on the assessment, a desired change to the initial shape of the cornea; and applying a cross-linking agent to the cornea; and', 'delivering an initiating element to the cornea,, 'generating the desired change to the initial shape of the cornea, includingwherein the initiating element activates the cross-linking agent to generate cross-linking activity that produces the desired change to the initial shape of the cornea.44. The method of claim 43 , wherein the one or more measurements of the eye include an optical power contour map of the eye claim 43 ,determining the assessment of the initial shape of the cornea includes analyzing optical power at one or more zones of the cornea,determining the desired change to the initial shape of the cornea includes determining changes to the optical power at the one or more zones of the cornea, andthe cross-linking activity produces the changes to the optical power at the ...

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23-08-2018 дата публикации

TRANSITION ZONE SYSTEMS AND METHODS

Номер: US20180235809A1
Автор: Dai Guang-ming
Принадлежит: AMO DEVELOPMENT LLC

A method of re-profiling a cornea of an eye is provided which includes causing ablation energy to be applied across the cornea of the eye and controlling distribution of the ablation energy across the cornea of the eye. The distribution of the ablation energy is controlled by causing the ablation energy to provide an ablation zone, having an optical zone disposed in a central portion of the anterior surface and a transition zone disposed peripherally to the optical zone on an anterior surface of the cornea the ablation zone, and determining a shape of the transition zone by selecting between a cubic spline function and a complementary error function. 1. A method of re-profiling a cornea of an eye , the method comprising:causing ablation energy to be applied across the cornea of the eye; andcontrolling distribution of the applied ablation energy across the cornea of the eye by: an optical zone disposed in a central portion of the anterior surface, and', 'a transition zone disposed peripherally to the optical zone; and, 'causing the ablation energy to provide an ablation zone on an anterior surface of the cornea, the ablation zone comprising;'}determining a shape of the transition zone by selecting between a cubic spline function and a complementary error function.2. The method according to claim 1 , wherein determining the shape of the transition zone further comprises:calculating, for one or more meridians across the cornea, a slope at an edge of the transition zone adjacent the optical zone;if the slope is greater than or equal to −2, selecting the cubic spline function to determine the shape of the transition zone; andif the slope is less than −2, selecting the complementary error function to determine the shape of the transition zone.3. The method of claim 2 , wherein the one or more meridians are myopic meridians.4. The method of claim 2 , wherein determining the transition zone by selecting the complementary error function further comprises:calculating an ...

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01-08-2019 дата публикации

LASER EYE SURGERY SYSTEM CALIBRATION

Номер: US20190231590A1
Принадлежит:

A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part. 123.-. (canceled)24. A system to treat an eye with a laser beam , the system comprising:a laser configured to generate the laser beam;a measurement system configured to measure first and second optically transmissive materials having differing indices of refraction;an optical delivery system coupled to the laser to deliver the laser beam to the second material through the first material; anda processor coupled to the measurement system and the optical delivery system, the processor configured to form a mark in the first or the second material with the laser beam per a target location, to measure a location of the mark with the measurement system, to calibrate the system by comparing the target location and the measured location of the mark using the indices of refraction, and to direct the beam toward a treatment target within the eye with the calibrated system.25. The system of claim 24 , wherein the processor is configured to form a plurality of marks in the first or second material at a plurality of locations.26. The system of claim 25 , wherein the plurality of marks define a volume and wherein laser beam is delivered at a plurality of locations within the volume.27. The system of claim 24 , wherein the processor is ...

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23-07-2020 дата публикации

CORNEAL TOPOGRAPHY MAPPING WITH DENSE ILLUMINATION

Номер: US20200229969A1
Автор: Fix Alexander Jobe
Принадлежит:

Techniques are described for generating and using an illumination pattern for corneal topography. The illumination pattern is projected onto an eye of a user wearing a head-mounted assembly. The illumination pattern is based on a reference pattern and corresponds to selective illumination of dots arranged along a two-dimensional grid. An image sensor captures a reflected image produced by reflection of the illumination pattern off the eye. A reflected pattern is identified based on glints in the reflected image and mapped to the reference pattern to generate an aligned reflected pattern. An eye model including a topography of a cornea is calculated by comparing the aligned reflected pattern to the reference pattern to determine a deviation in a shape of the cornea based on a difference between the aligned reflected pattern and the reference pattern. The eye model can be applied in various ways, including for eye tracking or biometric authentication. 1. A method , comprising:projecting an illumination pattern onto an eye of a user wearing a head-mounted assembly, the illumination pattern being based on a reference pattern and corresponding to selective illumination of dots arranged along a two-dimensional grid, wherein the dots form geometric features;capturing, using an image sensor, a reflected image produced by reflection of the illumination pattern off the eye;identifying a reflected pattern based on glints in the reflected image;generating an aligned reflected pattern based on mapping the reflected pattern to the reference pattern; andcalculating an eye model including a topography of a cornea of the eye, the calculating comprising comparing the aligned reflected pattern to the reference pattern to determine a deviation in a shape of the cornea based on a difference between the aligned reflected pattern and the reference pattern.2. The method of claim 1 , wherein the illumination pattern is non-rectilinear claim 1 , and wherein the reflected pattern is ...

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01-09-2016 дата публикации

CONFOCAL LASER EYE SURGERY SYSTEM AND IMPROVED CONFOCAL BYPASS ASSEMBLY

Номер: US20160250068A1
Принадлежит:

A method of reversibly separating an imaging assembly from an optical path in a laser surgical system includes generating an electromagnetic beam, propagating the electromagnetic beam from the beam source to a scanner along an optical path, the optical path comprising a first optical element that attenuates the electromagnetic beam, reversibly inserting a confocal bypass assembly into the optical path, diverting the electromagnetic beam along a diversion optical path around the first optical element, wherein the confocal bypass assembly automatically exits the optical path when a power loss occurs to one or more components of the system. 1. A method of reversibly separating an imaging assembly from an optical path in a laser surgical system , the method comprising:using a beam source to generate an electromagnetic beam;propagating the electromagnetic beam from the beam source to a scanner along an optical path, the optical path comprising a first optical element that attenuates the electromagnetic beam, the first optical element being positioned between the beam source and the scanner;focusing the electromagnetic beam to a focal point at a location within the eye;using the scanner to scan the focal point to different locations within the eye;propagating a portion of the electromagnetic beam reflected from the focal point location back along the optical path to the first optical element, the first optical element diverting a portion of the reflected electromagnetic radiation to a sensor;using the sensor to generate an intensity signal indicative of an intensity of a portion of the electromagnetic beam reflected from the focal point location and propagated to the sensor via the first optical element; andreversibly inserting a confocal bypass assembly into the optical path, diverting the electromagnetic beam along a diversion optical path around the first optical element, wherein the beam direction and position are substantially the same at the entry of and exit from ...

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30-08-2018 дата публикации

OPHTHALMIC TREATMENT APPARATUS AND METHOD FOR CONTROLLING SAME

Номер: US20180243129A1
Автор: Ha Tae Ho
Принадлежит:

The present invention relates to an ophthalmic treatment apparatus and a method for controlling same. The ophthalmic treatment apparatus according to the present invention comprises: an image unit for generating an image of the retina area of an eyeball in a horizontal direction with respect to the plane of the focal spot of a therapeutic beam directed by a beam delivery unit; a pattern unit for providing a grid pattern to the retina area so as to correspond to the curvature of the retina area generated by the image unit; and a control unit for controlling the operation of a beam generation unit and the beam delivery unit to radiate the therapeutic beam to the intersection points of the grid pattern on the basis of the grid pattern provided by the pattern unit. 1. An ophthalmic treatment apparatus having a beam generation unit for generating a therapeutic beam and a beam delivery unit for guiding the therapeutic beam into the eyeball , the ophthalmic treatment apparatus comprising:an image unit for generating an image of a retina region of the eyeball in the lateral direction with respect to a plane of a focal spot of the therapeutic beam guided by the beam delivery unit;a pattern unit for providing a grid pattern to the retina region corresponding to a curvature of the retina region generated by the image unit; anda control unit for controlling operation of the beam generation unit and the beam delivery unit to irradiate intersecting points of the grid pattern with the therapeutic beam based on the grid pattern provided by the pattern unit.2. The apparatus according to claim 1 , wherein the plane of the focal spot comprises:a first plane forming a tangent plane at an arc of the retina region through which an optical axis of the therapeutic beam passes; anda second plane which is parallel to the first plane along the optical axis and connects both sides of an arc while interposing a point of contact of the retina region therebetween.3. The apparatus according to ...

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15-08-2019 дата публикации

DEVICE AND METHOD FOR PRODUCING CONTROL DATA FOR THE SURGICAL CORRECTION OF DEFECTIVE EYE VISION

Номер: US20190247225A1
Принадлежит:

A device for producing control data for a laser device for the surgical correction of defective vision. The device produces the control data such that the laser emits the laser radiation such that a volume in the cornea is isolated. The device calculates a radius of curvature R* to determine the control data, the cornea reduced by the volume having the radius of curvature R* and the radius of curvature being site-specific and satisfying the following equation: R*(r,φ)=1/((1/R(r,φ))+B(r,φ)/(n-1))+F, wherein R(r,φ) is the local radius of curvature of the cornea before the volume is removed, nis the refractive index of the material of the cornea, F is a coefficient, and B(r,φ) is the local change in refractive force required for the desired correction of defective vision in a plane lying in the vertex of the cornea, and at least two radii r1 and r2 satisfy the equation B(r=r1,φ)≠B(r=r2,φ). 1. (canceled)2. A method for surgical correction of defective vision of an eye of a patient , the method comprising:changing a curvature of a cornea of the eye by generating a cut in the cornea by irradiating laser radiation into the cornea, wherein the cut circumscribes and isolates a volume of cornea tissue within in the interior of the cornea, andremoving the isolated volume of cornea tissue from within the cornea,making the cut circumscribing and isolating the volume to comprise an anterior and a posterior part, the anterior part lying at a constant distance from a cornea front surface, and{'b': 1', '2, 'wherein the curvature of the cornea of the eye is changed by removal of the volume differently for at least two radii, r and r, around an optical axis.'}3. The method according to claim 2 , further comprising changing the curvature of the cornea of the eye by removal of the volume such that near vision is corrected in a central area about the optical axis claim 2 , defined by a radius of a phototopic pupil and that a distant vision is corrected in a zone having greater diameters. ...

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21-10-2021 дата публикации

LASER EYE SURGERY SYSTEM CALIBRATION

Номер: US20210322211A1
Принадлежит:

A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part. 124.-. (canceled)25. A method implemented in a laser system for treating an eye with a laser beam , the eye having first and second optically transmissive materials having differing indices of refraction , the method comprising:by a laser, generating the laser beam;by a processor, controlling the laser and an optical delivery system to deliver the laser beam to the eye to form a plurality of marks in both the first material and the second material per a plurality of target locations, wherein the marks in the first material and the second material together define a three dimensional calibration volume in the eye that includes both the first material and the second material;by a measurement system, measuring a plurality of locations of the marks in the first material and the second material;by a processor, determining a calibration of the laser system for the calibration volume by comparing the target locations and the measured locations of the marks using the indices of refraction of the first and second materials; andby the processor, and based on the calibration, controlling the laser and the optical delivery system to deliver the laser beam to a treatment target located within the calibration volume within the eye.26. The ...

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21-09-2017 дата публикации

APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER OPHTHALMIC SURGERY

Номер: US20170266042A1
Принадлежит:

System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.

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13-08-2020 дата публикации

Liquid patient interface

Номер: US20200253781A1
Принадлежит: CARL ZEISS MEDITEC AG

A liquid-patient interface for fixing the relative geometric position and orientation of a patient's eye with respect to a laser applicator of an ophthalmological laser therapy system. The liquid-patient interface includes a lens element and a cone element, wherein the lens element is inserted into the cone element and permanently connected to the cone element such that the liquid-patient interface has an integral configuration. The invention furthermore relates to a corresponding production method for such a liquid-patient interface. The liquid-patient interface, the lens element of which is embodied in one piece and contains an optical zone, which has a lens function, and an envelope region, adjoining the optical zone, having a defined height not equal to zero and having an upper edge, wherein the upper edge of the lens element facilitates a direct connection to the laser applicator.

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20-08-2020 дата публикации

INTELLIGENT CORNEAL PROCEDURE ADVISOR

Номер: US20200261264A1
Автор: Lobanoff Mark
Принадлежит:

Generation of treatment recommendations for topographic-based excimer laser surgical procedures is described that includes generating accurate cylinder compensation and spherical compensation values that are adjusted to compensate for unique characteristics of topographic-based excimer laser surgical systems. Generating treatment recommendations generally includes determining a topographic vector, a posterior astigmatism vector and an anterior astigmatism vector, and generating an internal astigmatism vector using the topographic vector, the posterior astigmatism vector, the anterior astigmatism vector, and a manifest astigmatism vector. In embodiments, the cylinder compensation is generated using multiple vectors while subtracting the internal astigmatism vector and the posterior astigmatism vector which remain in the eye after treatment, and the spherical compensation is generated using an initial spherical compensation modified by addback modifiers and a regression analysis nomogram. In procedures where the corneal epithelium is removed, an epithelial refractive vector is determined from an epithelial thickness/topography map and added to the other vectors. 1. An intelligent advisor system for generating a treatment recommendation for corneal surgical procedures on an eye , the treatment recommendation including a cylinder compensation and a spherical compensation , the system comprising:a processor; and determine a topographic vector from a topographic corneal map of the eye, the topographic vector indicating a magnitude and a direction of an optical effect of a corneal talus;', 'determine an epithelial thickness topographic vector from a topographic corneal epithelium map of the eye, the epithelial thickness topographic vector indicating a magnitude and a direction of an optical effect of an epithelial talus;', 'determine a posterior astigmatism vector and an anterior astigmatism vector for the eye;', 'generate an interior astigmatism vector using the ...

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15-10-2015 дата публикации

MANIFEST REFRACTION TREATMENT SYSTEMS AND METHODS

Номер: US20150290032A1
Автор: Brownell Michael
Принадлежит:

Embodiments of the present invention encompass systems and techniques for developing a vision prescription for a patient based on an objective optical manifest refraction, such as that measured with a wavefront device, without altering the prescription in response to any subjective manifest refraction, such as that measured with a phoropter device. 1. A method for treating an eye of a patient , the method comprising:measuring, with a manifest refraction instrument, an objective optical manifest refraction of the eye of the patient;transmitting the objective optical manifest refraction measurement from the manifest refraction instrument to a treatment planner;determining, with the treatment planner, a prescription based on the objective optical manifest refraction measurement, without altering the prescription in response to any subjective manifest refraction measurement of the eye; andtransmitting the prescription from the treatment planner so as to facilitate surgically altering the eye per the prescription.2. The method according to claim 1 , wherein the objective optical manifest refraction measurement comprises a wavefront evaluation of the eye.3. The method according to claim 1 , wherein the objective optical manifest refraction measurement comprises a combined wavefront and topographic evaluation of the eye.4. The method according to claim 1 , further comprising interactively claim 1 , in response to subjective input from the patient claim 1 , measuring the subjective manifest refraction of the eye claim 1 , the subjective manifest refraction measurement differing significantly from the optical manifest refraction measurement.57.-. (canceled)8. The method according to claim 4 , wherein the objective optical manifest refraction measurement transmitted from the manifest refraction instrument differs from the subjective manifest refraction measurement by more than about 0.50 Diopters.9. The method according to claim 4 , wherein the subjective manifest refraction ...

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11-10-2018 дата публикации

Systems and methods for corneal laser ablation

Номер: US20180289545A1
Автор: Manoj MOTWANI
Принадлежит: Individual

Systems and methods for corneal laser ablation for primary vision correction include topographic guided ablation. A laser ablation pattern for removal of astigmatism is derived at least in part from corneal topographic data rather than manifest astigmatism. Laser ablation patterns for treatment of high order aberrations of the cornea may also be based on corneal topographic data. Spherical corrections may be based on manifest refraction, eye models, or wavefront aberrometry.

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20-10-2016 дата публикации

Customized laser epithelial ablation systems and methods

Номер: US20160302968A1
Принадлежит: AMO DEVELOPMENT LLC

Systems and methods to treat a region of a cornea of an eye having an epithelial layer disposed over a stromal layer. The system comprises a device to map a thickness of the epithelial layer over the region of the cornea to generate a map of epithelial thickness over the region, and a laser to generate a laser beam of an ablative radiation. A movable scan component is coupled to the laser to scan the laser beam over the region. A processor system is coupled to the laser and the movable scan component, and the processor system is configured to arrange pulses of laser beam to ablate the epithelial layer of the region in response to the map of epithelial thickness.

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29-10-2015 дата публикации

DEVICE AND METHOD FOR PRODUCING CONTROL DATA FOR THE SURGICAL CORRECTION OF THE DEFECTIVE VISION OF AN EYE

Номер: US20150305928A1
Принадлежит:

A device for producing control data for a laser device for the surgical correction of defective vision. The device generates the control data to control the laser, the optics and the scanner to cut the cornea by focusing the laser radiation and by shifting the position of the focus within the cornea. The control data controls the scanner to shift the position of the focus within the cornea. The device generates the control data such that the laser, the optics and the scanner emit and focus the laser radiation such, that a volume in the cornea is isolated. The removal of which volume from the cornea effects a desired correction of the defective vision. To determine the control data, the device is configured to calculate a radius of curvature R* of the cornea reduced by the volume wherein the radius of curvature R* is locally varying. 123-. (canceled)24. A device for generating control data that control a laser system for surgical correction of defective vision of an eye of a patient , wherein:the laser system comprises a laser for emitting laser radiation, optics for focusing the laser radiation to a focus and a scanner for shifting a position of the focus;the device generates the control data to be adapted to control the laser, the optics and the scanner to cut the cornea by focusing the laser radiation into the cornea of the eye and by shifting the position of the focus within the cornea;wherein the control data includes data to control the scanner to shift the position of the focus within the cornea;wherein the device generates the control data such that the laser, the optics and the scanner, during operation under the control data, emit and focus the laser radiation such, that a volume in the cornea is isolated, the removal of which volume from the cornea effects a desired correction of the defective vision; and{'sub': 'CV', 'to determine the control data, the device is configured to calculate a radius of curvature R* of the cornea reduced by the volume;'}{'sub': ...

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24-09-2020 дата публикации

Method for controlling an eye surgical laser and treatment device

Номер: US20200297537A1
Принадлежит: Schwind Eye Tech Solutions GmbH

A method for controlling an eye surgical laser for the separation of a volume body with predefined posterior and anterior interfaces from a human/animal cornea is disclosed. The method including controlling the laser by means of a control device wherein the laser emits pulsed laser pulses in a predefined pattern into the cornea. The interfaces of the volume body are defined by the predefined pattern and are generated by means of an interaction of the individual laser pulses with the cornea by means of photodisruption. The control device controls the laser beam such that both interfaces are generated by means of a continuous, uninterrupted sequence of laser pulses. A treatment device is disclosed with at least one eye surgical laser for the separation of a predefined corneal volume with predefined interfaces of a human/animal eye by means of photodisruption and with at least one control device for the laser(s).

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19-11-2015 дата публикации

Precise Targeting Of Surgical Photodisruption

Номер: US20150328045A1
Принадлежит:

Techniques, apparatus and systems for laser surgery including imaging-guided surgery techniques, apparatus and systems.

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09-11-2017 дата публикации

METHODS AND SYSTEMS FOR CORNEAL TOPOGRAPHY, BLINK DETECTION AND LASER EYE SURGERY

Номер: US20170323450A1
Автор: Gonzalez Javier G.
Принадлежит:

A method of blink detection in a laser eye surgical system includes providing a topography measurement structure having a geometric marker. The method includes bringing the topography measurement structure into a position proximal to an eye such that light traveling from the geometric marker is capable of reflecting off a refractive structure of the eye of the patient, and also detecting the light reflected from the structure of the eye for a predetermined time period while the topography measurement structure is at the proximal position. The method further includes converting the light reflected from the surface of the eye into image data and analyzing the image data to determine whether light reflected from the geometric marker is present is in the reflected light, wherein if the geometric marker is determined not to be present, the patient is identified as having blinked during the predetermined time. 123.-. (canceled)24. A laser eye surgical system capable of blink detection , comprising:a topography measurement structure having at least one geometric marker, the topography measurement structure being configured to be placed into a position proximal to an eye of a patient such that light traveling from the at least one geometric marker is capable of reflecting off a refractive structure of the eye of the patient;an image capture device configured to detect light reflected from the eye of the patient for a predetermined time period while the topography measurement structure is at the proximal position, and to convert the detected light into image data; andcontrol electronics coupled to the image capture device and configured to analyze the image data to determine whether light corresponding to the geometric marker is detected in the reflected light, wherein if the light corresponding to the geometric marker is determined not to be present, the control electronics identifies the patient as having blinked during the predetermined time.25. The laser eye surgical ...

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08-11-2018 дата публикации

SYSTEMS AND METHODS FOR CORNEAL LASER ABLATION

Номер: US20180318134A1
Автор: Motwani Manoj
Принадлежит:

Systems and methods for corneal laser ablation for primary vision correction include topographic guided ablation. A laser ablation pattern is derived at least in part from corneal topographic data and epithelial thickness data. The laser ablation pattern may limit post-surgical non-uniformity of the thickness of the epithelial layer. 1. A corneal laser ablation system comprising:a corneal topography measuring instrument;a corneal epithelium thickness mapping instrument;a laser system configured to emit pulsed laser light at one or more wavelengths and configured to control the parameters of laser emission such that the laser output is suitable for controlled ablation of an anterior corneal surface;wherein the laser system is configured to control the laser output to ablate at least some high order aberrations from the anterior corneal surface based at least in part on both topographical measurements of the anterior corneal surface made with the corneal topography measuring instrument and corneal epithelium thickness measurements made with the corneal epithelium thickness mapping instrument.2. The corneal laser ablation system of claim 1 , wherein the laser system is configured to control the laser output to ablate the anterior corneal surface to limit post-surgical epithelial non-uniformity in an ablation treatment zone.3. The corneal laser ablation system of claim 1 , wherein the laser system is configured to control the laser output to ablate the anterior corneal surface to limit post-surgical epithelial non-uniformity to less than or equal to 6 micrometer variation within a 6 mm diameter ablation treatment zone as measured with optical coherence tomography six months after laser ablation.4. The corneal laser ablation system of claim 1 , wherein the laser system is configured to control the laser output to ablate the anterior corneal surface to limit post-surgical epithelial non-uniformity to less than or equal to 3 micrometer variation within a 6 mm diameter ...

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03-12-2015 дата публикации

Treatment Systems for Vitreous Floaters

Номер: US20150342782A1
Принадлежит: Strathspey Crown Holdings, LLC

In accordance with the present invention, a system and method are provided for using a computer-controlled, laser system to perform a partial vitrectomy of the vitreous humor in an eye. Operationally, an optical channel is first defined through the vitreous humor. Vitreous and suspended deposits (floaters) in the optical channel are then ablated and in some cases removed (e.g. aspirated) from the optical channel. In some instances, a clear liquid can be introduced into the optical channel to replace the ablated matter, and to thereby establish unhindered transparency in the optical channel. 1. A method for removing deposits from an optical channel to establish transparency in the channel , wherein the optical channel is defined to extend through an otherwise clear gel-like substance in the channel , the method comprising the steps of:identifying an axis, wherein the axis extends through the gel-like substance;defining an optical channel through the gel-like substance, wherein the optical channel is substantially cylindrical shaped and extends radially outward to a distance r from the axis; andablating the gel-like substance in the optical channel, and deposits suspended therein.2. A method as recited in further comprising the steps of:aspirating the ablated gel-like substance to remove the deposits therewith from the optical channel; andintroducing a fluid into the optical channel to replace the aspirated gel-like substance and the deposits removed therefrom during the aspirating step to establish a transparent optical channel and wherein the ablating step is accomplished using a laser beam to photoalter the gel-like substance and the deposits in the optical channel.3. A method as recited in wherein the gel-like substance is the vitreous humor of an eye and the optical channel extends between the posterior surface of the lens of the eye and the retina of the eye.4. A method as recited in wherein the ablating step is accomplished in the optical channel at a distance ...

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24-10-2019 дата публикации

LASER APPARATUS AND METHOD FOR REFRACTIVE SURGERY

Номер: US20190321227A1
Принадлежит:

An ultrashort pulsed laser instrument is used to perform refractive surgery. The invention operates in ablative and incisional modalities. In the ablative mode, spiral ablation disks consisting of individual laser pulses are produced at high scanning speeds. Ablation profile may be produced in cornea by stacking and arranging multiple ablation disks to produce a specified shape change. Placement of ablation disks is assisted by an optical tracking and control system that compensates for eye motion. A preferred embodiment allows for ablative corrections to be performed on non-planar posterior surface of a laser cut flap affixed to registration platen, thereby avoiding exposing the eye interior to high radiant power. Laser cut and contrast agent dyed fiduciary marks may serve as reference features for the optical tracking system. Incisional procedures, such as corneal flaps for LASIK, may also be performed. 1. A laser instrument comprising:a laser source generating a laser pulse train of ultrashort duration pulses;an optical processing module configured to control and modulate said laser pulse train;a scanning beam delivery module for scanning in three dimensions the focal point of said laser pulse train;a focusing optics module for focusing said laser pulse train onto biological tissue for the purpose of removing said tissue;an optical tracking system for detecting relative lateral and axial motions between said laser pulse train and said tissue; anda means for adjusting and compensating the delivery of said laser pulse train to said tissue using said optical tracking system to correct for said lateral and axial motionswherein the laser pulse train of ultrashort duration pulses produce a discrete ablation sequence, and wherein a wavelength and intensity of the laser source remain unchanged during the production of the ablation sequence.2. The laser instrument of claim 1 , wherein the instrument removes a designated volume of said biological tissue through a series of ...

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01-12-2016 дата публикации

METHOD FOR GENERATING AN ABLATION PROGRAM, METHOD FOR ABLATING A BODY AND MEANS FOR CARRYING OUT SAID METHOD

Номер: US20160346118A1
Принадлежит:

In a method for generating an ablation program for ablation of material from a surface of a body according to a predetermined desired ablation profile by emission of pulses of a pulsed laser beam onto the surface, the ablation program is generated from the desired ablation profile as a function of the shape of a beam profile of the laser beam and of an inclination of the surface to be ablated and/or considering a water content of the material to be ablated. 1. A method for generating an ablation program for ablation of material from a surface of a body according to a predetermined desired ablation profile by emission of pulses of a pulsed laser beam onto the surface , the method comprising:generating the ablation program from the predetermined desired ablation profile as a function of the shape of a beam profile of the laser beam and as a function of an inclination of the surface to be ablated;using the predetermined desired ablation profile to determine a pre-compensated desired ablation profile as a function of a refractive index of the material at a respective target location of the surface; andgenerating the ablation program on a basis of the pre-compensated desired ablation program.2. The method as claimed in claim 1 , further comprising claim 1 , in order to consider the inclination of the surface and the shape of the beam profile claim 1 , using the predetermined desired ablation profile to determine the pre-compensated desired ablation profile as a function of at least one of a shape of the beam profile and the inclination of the surface at the respective target location on the surface; andgenerating the ablation program on the basis of the pre-compensated desired ablation program.3. The method as claimed in claim 2 , further comprising claim 2 , for at least two regions to be ablated from the surface claim 2 , respectively determining one value of a modification function as a function of at least one of the shape of the beam profile and the inclination of ...

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30-11-2017 дата публикации

SYSTEMS FOR SHORT PULSE LASER EYE SURGERY

Номер: US20170340483A1
Принадлежит: CARL ZEISS MEDITEC AG

A system for short pulse laser eye surgery and a short pulse laser system, in which a beam guidance device passes through a corresponding articulated arm, and through an applicator head and a microscope head of the system, which is movable in a three-dimensional volume both independently of one another as well as connected to each other. The system also includes, an easy-to-use patient interface with a one-piece contact element, a computer program product for methods of the incision guidance and sequentially operating referencing methods with patient interfaces containing markings. 172.-. (canceled)73. A system for short pulse laser eye surgery , comprisinga short pulse laser system including a short pulse laser source, a beam guidance device and an applicator head for directing a short pulse laser radiation from the short pulse laser source to the eye to be operated on;a surgical microscope having a microscope head; anda control unit adapted to control the system for the short pulse laser eye surgery;a housing enclosing at least the short pulse laser source, and supporting a first and a second articulated arm arranged at the housing or at an extension of the housing;wherein the microscope head is operably coupled to the first articulated arm and the applicator head is operably coupled to the second articulated arm;further comprising an interface between the applicator head and the microscope head, by which the applicator head and the microscope head are releasably connectable both mechanically and optically;wherein the beam guidance device passes through the second articulated arm; andwherein the applicator head and the microscope head are movable in a three-dimensional volume independently from each other as well as connected to each other via the interface.74. The system for short pulse laser eye surgery according to claim 73 , further comprising an optical coherence tomography (OCT) module containing an OCT light source claim 73 , an interferometer and a ...

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22-10-2020 дата публикации

SYSTEMS AND METHODS FOR SHORT PULSE LASER EYE SURGERY

Номер: US20200330278A1
Принадлежит:

A system for short pulse laser eye surgery and a short pulse laser system, in which a beam guidance device passes through a corresponding articulated arm, and through an applicator head and a microscope head of the system, which is movable in a three-dimensional volume both independently of one another as well as connected to each other. The system also includes an easy to use patient interface with a one-piece contact element, a computer program product for methods of the incision guidance and sequentially operating referencing methods with patient interfaces containing markings. 1. (canceled)2. A patient interface for fixing a position of an eye relative to a system for short pulse laser eye surgery , the patient interface comprising:a contact element;wherein the contact element comprises a unitary one piece structure, formed of a transparent or partially transparent material and includes a suction ring, a casing and an optical element proximate an upper side of the casing; andwherein the casing defines at least one opening, to which is connectable respectively a feed line via a fixing aid or which respectively permits connection of a lead.3. The patient interface according to claim 2 , wherein the casing defines two openings.4. The patient interface according to wherein the casing further defines a further suction structure facing of the transparent material at the contact element on a side of the casing facing away from the suction ring.5. The patient interface according to claim 2 , wherein the optical element is arranged in an inclined manner relative to an optical axis of the system for short pulse laser eye surgery.6. The patient interface according to claim 2 , wherein a surface of the optical element facing the eye further comprises a hydrophilic coating or is surface-treated to make the surface hydrophilic and/or is convexly curved whereby migration of bubbles peripherally and upwardly and away from an optical aperture is facilitated.7. The patient ...

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08-12-2016 дата публикации

APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER OPHTHALMIC SURGERY

Номер: US20160354247A1
Принадлежит:

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions. 120-. (canceled)21. A laser surgical system for making incisions in ocular tissue during a cataract surgical procedure , the system comprising:a laser system comprising a scanning assembly;a laser operable to generate a pulsed laser beam configured to incise ocular tissue, the pulsed laser beam comprising a plurality of laser pulses;an imaging device configured to acquire image data of at least a portion of the ocular tissue; and operate the imaging device to acquire image data;', 'identify a location of one or more treatment targets based in part of the image data;', 'operate the scanning assembly to position a focal zone of the laser beam at a predetermined position in the ocular tissue; and', 'operate the laser and the scanning assembly to scan the focal zone of the pulsed laser beam in a treatment scanning pattern, each of the plurality of laser pulses scanned in the treatment scanning pattern sufficient to create a rupture zone in the ocular tissue;', 'wherein positioning of the focal zone in the treatment scanning pattern is determined in part by the control system based on the image data., 'a control system operably coupled to the laser system and ...

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17-12-2015 дата публикации

BASIS DATA EVALUATION SYSTEMS AND METHODS

Номер: US20150359602A1
Автор: Dai Guang-ming
Принадлежит:

Systems, methods, and computer program products are provided for the administration of ablation profiles during refractive surgery treatments. Basis data framework techniques enable the implementation of ablation profiles having various shapes, resulting in increased ablation accuracy when treating certain vision conditions. Exemplary basis data architecture approaches are configured to efficiently operate with annular, elliptical, and slit laser beam shapes. 1. A method of determining a treatment basis data for use in a laser ablation vision procedure for a patient , the method comprising:inputting an initial basis data, the initial basis data comprising a set of pulse profiles;inputting a first treatment target for a first individual, the first treatment target based on a wavefront measurement, a topography measurement, or both for the first individual and the initial basis data;generating a predicted surgery outcome for the first individual, the predicted surgery outcome based on the first treatment target and a healing kernel;comparing the predicted surgery outcome with an actual surgery outcome for the first individual; anddetermining, via a processing module comprising a tangible medium embodying machine-readable code, the treatment basis data for use in the laser ablation vision procedure, wherein the treatment basis data is based on the initial basis data and the comparison between the predicted surgery outcome and the actual surgery outcome for the first individual, and wherein the treatment basis data comprises a set of pulse profiles that differs from the set of pulse profiles of the initial basis data.2. The method according to claim 1 , further comprising determining a patient treatment target for the patient claim 1 , the patient treatment target based on the treatment basis data and a wavefront measurement for the patient.3. The method according to claim 2 , further comprising delivering the patient treatment target to the patient.4. The method ...

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07-11-2019 дата публикации

CLOSED-LOOP LASER EYE SURGERY TREATMENT

Номер: US20190336340A1
Принадлежит:

A laser eye surgery system includes a laser to generate a laser beam. A topography measurement system measures corneal topography. A processor is coupled to the laser and the topography measurement system, the processor embodying instructions to measure a first corneal topography of the eye. A first curvature of the cornea is determined. A target curvature of the cornea that treats the eye is determined. A first set of incisions and a set of partial incisions in the cornea smaller than the first set of incisions are determined. The set of partial incisions is incised on the cornea by the laser beam. A second corneal topography is measured. A second curvature of the cornea is determined. The second curvature is determined to differ from the target curvature and a second set of incisions are determined. The second set of incisions is incised on the cornea. 110.-. (canceled)11. A laser eye surgery system , comprising:a laser system to generate a laser beam and direct the laser beam to an eye of a patient;a topography measurement system for measuring topography of a cornea of the eye; measure a first corneal topography of the eye using the topography measurement system;', 'determine a first curvature of the cornea based on the first corneal topography, and determine a target curvature of the cornea that treats the eye;', 'determine a first set of incisions in the cornea to achieve the target curvature of the corneal;', 'determine a first set of first partial incisions in the cornea, wherein the first partial incisions are smaller than the incisions of the first set of incisions;', 'perform the first set of first partial incisions on the cornea using the laser system;', 'measure a second corneal topography using the topography measurement system after performing the first set of first partial incisions;', 'determine a second curvature of the cornea based on the second corneal topography;', 'determine whether the second curvature differs from the target curvature by more ...

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15-12-2016 дата публикации

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Номер: US20160361198A1
Принадлежит:

A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors. 1. (canceled)2. A system , comprising: the measurement device generates measurement data of parameters of the eye and defective-eyesight data of the defective eyesight of the eye and supplies the data to the planning device,', 'the planning device generates the control data for the treatment apparatus which separates eye tissue by focusing pulsed laser radiation to target points within the eye,', 'wherein the planning device defines a boundary surface by using the measurement data and the defective-eyesight data, and, 'a planning device for determining control data for a treatment apparatus for surgical correction of defective eyesight in an eye of a patient and a measurement device connected to the planning device, wherein'}generates for said boundary surface a control dataset to control the laser device, which control dataset defines a three-dimensional pattern of the target points in the eye, which are located in the boundary surface and are arranged such that the boundary surface is obtained as a cut surface when the pulsed laser radiation is irradiated according to the control dataset.3. The system of claim 2 , wherein the planning device defines a volume by using the measurement ...

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24-12-2015 дата публикации

APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER OPHTHALMIC SURGERY

Номер: US20150366712A1
Принадлежит: OPTIMEDICA CORPORATION

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions. 121-. (canceled)22. A system for ophthalmic surgery on an eye , comprising:a. a pulsed laser configured to produce a treatment beam which creates dielectric breakdown in a focal zone of the treatment beam within one or more ocular tissues of the eye in a posterior pole of the eye;b. a three-dimensional, optical coherence tomography imaging assembly capable of creating a continuous depth profile of the eye, the profile comprising information regarding the location of the one or more ocular tissues of the eye in the posterior pole, by detecting remitted illumination light from locations distributed throughout a volume of the one or more ocular tissues in the posterior pole, and generating signals based upon the remitted light;c. an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole; and ["i. scan tissues of the patient's eye with the imaging assembly so as to generate image data signals to create a profile of the one or more ocular tissues in the posterior pole;", 'ii. identify one or more boundaries of the one or more floaters based at ...

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13-12-2018 дата публикации

METHODS AND SYSTEMS FOR CORNEAL TOPOGRAPHY, BLINK DETECTION AND LASER EYE SURGERY

Номер: US20180357771A1
Автор: Gonzalez Javier G.
Принадлежит:

A method of blink detection in a laser eye surgical system includes providing a topography measurement structure having a geometric marker. The method includes bringing the topography measurement structure into a position proximal to an eye such that light traveling from the geometric marker is capable of reflecting off a refractive structure of the eye of the patient, and also detecting the light reflected from the structure of the eye for a predetermined time period while the topography measurement structure is at the proximal position. The method further includes converting the light reflected from the surface of the eye into image data and analyzing the image data to determine whether light reflected from the geometric marker is present is in the reflected light, wherein if the geometric marker is determined not to be present, the patient is identified as having blinked during the predetermined time. 123-. (canceled)24. A method , comprising:providing to an eye of a patient a light pattern produced by one or more geometric markers of a corneal topography measurement structure; detecting light returned from the eye of the subject while providing the light pattern to the eye,', 'converting the light returned from the eye into corresponding image data,', 'analyzing the image data to determine whether the light pattern is present in the detected light,', 'when it is determined that the light pattern is present in the detected light, using at least a portion of the image data corresponding to the light pattern to make a corneal topography measurement of a cornea of the eye of the subject, and', 'when it is determined that the light pattern is not present in the detected light, determining that the subject blinked and excluding the image data from the corneal topography measurement of the eye of the subject., 'for each of a plurality of time periods25. The method of claim 24 , wherein the light pattern includes at least one circular portion.26. The method of claim 24 ...

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21-11-2019 дата публикации

CORNEAL TOPOGRAPHY MEASUREMENTS AND FIDUCIAL MARK INCISIONS IN LASER SURGICAL PROCEDURES

Номер: US20190350760A1
Принадлежит:

A method of cataract surgery in an eye of a patient includes identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography and forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye. A laser cataract surgery system a laser source, a topography measurement system, an integrated optical subsystem, and a processor in operable communication with the laser source, corneal topography subsystem and the integrated optical system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine one of an axis, meridian and structure of an eye of the patient based on the measurements received from topography measurement system, and direct the treatment beam so as to incise radial fiducial mark incisions. 1. A method of cataract surgery in an eye of a patient comprising:identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography;forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye.2. The method of claim 1 , wherein the feature is a meridian of the cornea.3. The method of claim 2 , wherein the meridian is the steepest meridian.4. The method of claim 1 , wherein the fiducial mark incisions are instrasomal corneal incisions.5. The method of claim 1 , wherein the fiducial mark incisions do not alter the optical properties of the eye.6. The method of claim 5 , wherein the length of each fiducial mark incision is less than 1.5 mm.7. The method of claim 1 , wherein identifying the feature comprises measuring the corneal topography with one or more of a keratometry system claim 1 , an optical coherence tomography system claim 1 , a Placido disc topography system claim 1 , a Hartmann-Shack topography system claim 1 , a Scheimpflug image ...

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28-11-2019 дата публикации

LASER EYE SURGERY LENS FRAGMENTATION

Номер: US20190358084A1
Принадлежит:

A laser eye surgery system includes a laser to generate a laser beam. A spatial measurement system generates a measurement beam and measure a spatial disposition of an eye. A processor is coupled to the laser and the spatial measurement system, the processor comprising a tangible medium embodying instructions to determine a spatial model of the eye in an eye coordinate reference system based on the measurement beam. The spatial model is mapped from the eye coordinate reference system to a machine coordinate reference system. A laser fragmentation pattern is determined based on a plurality of laser fragmentation parameters. The laser fragmentation pattern and the spatial model is rotated by a first rotation angle such that the spatial model is aligned with the reference axis of the machine coordinate reference system and the rotated laser fragmentation pattern is aligned with the corneal incision. 1. A laser eye surgery system , comprising:a laser to generate a laser beam;a spatial measurement system to generate a measurement beam and measure a spatial disposition of an eye;a processor coupled to the laser and the spatial measurement system, the processor comprising a tangible medium embodying instructions to:determine a spatial model of the eye in an eye coordinate reference system based on the measurement beam;map the spatial model from the eye coordinate reference system to a machine coordinate reference system;receive a rotation angle of a corneal incision relative to a reference axis of the machine coordinate reference system;determine a laser fragmentation pattern based on a plurality of laser fragmentation parameters;determine a first rotation angle based on the rotation angle of the corneal incision and a rotation angle of the laser fragmentation pattern relative to the reference axis of the machine coordinate reference system;rotate the spatial model by a negative of the first rotation angle; androtate the laser fragmentation pattern and the spatial model by ...

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31-12-2020 дата публикации

PLANNING DEVICE AND METHOD FOR GENERATING CONTROL DATA FOR AN OPHTHALMOLOGICAL LASER THERAPY DEVICE FOR STRUCTURES BRIDGING THE CORNEA IN A PRESSURE-REDUCING MANNER

Номер: US20200405539A1
Принадлежит: CARL ZEISS MEDITEC AG

A planning device that generates control data for an ophthalmological laser therapy appliance with a laser device and a control unit, includes a first interface for supplying various data and a second interface for transferring the control data to the control unit of the ophthalmological laser therapy appliance, which is embodied to generate control data for a scanning pattern for the ophthalmological laser therapy appliance from the supplied data, by application of which scanning pattern a structure can be produced in the cornea, the limbus, and/or the sclera of a patient's eye. The planning device is embodied to generate from the supplied data, control data for the scanning pattern of this structure and/or a structure for receiving the shunt implant. 135.-. (canceled)36. A planning device for generating control data for an ophthalmological laser therapy appliance , the laser therapy appliance comprising a laser device with a laser source that generates a pulsed laser beam , with a focusing apparatus that focuses the pulsed laser beam on a focus , and with a scanning apparatus that scans the focus of the pulsed laser beam in a tissue of a patient's eye , in including a cornea , a limbus , and/or a sclera , that modifies microstructures or severs the tissue along a scanning pattern of focus spots of the focus of the pulsed laser beam in accordance with the control data , and a control unit that controls the ophthalmological laser therapy appliance by application of the control data ,wherein the planning device comprises a first interface that supplies data of a characterization of the patient's eye, including the cornea, the limbus, and/or the sclera of the patient's eye, and that supplies data of a model of a shunt implant for pressure-reducing bridging of the cornea and/or data of a structure, to be generated in the cornea, the limbus, and/or the sclera, for pressure-reducing bridging of the cornea, and a second interface that transfers the control data to a ...

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31-12-2020 дата публикации

Surgical system and procedure for precise intraocular pressure reduction

Номер: US20200405542A1
Автор: Ferenc Raksi
Принадлежит: Vialase Inc

An initial treatment pattern defining an initial volume of ocular tissue to be modified for treating glaucoma is designed. An initial laser treatment is delivered by scanning a laser beam across ocular tissue at an initial placement in the eye in accordance with the initial treatment pattern to thereby photo disrupt the initial volume of ocular tissue. A postoperative measure of intraocular pressure (IOP) is evaluated relative to an IOP criterion to determine if the treatment was successful. If the treatment was not successful, meaning the IOP criterion was not satisfied, then a subsequent treatment pattern that defines a subsequent volume of ocular tissue to be modified, and/or a subsequent placement in the eye is determined. A subsequent laser treatment is delivered by scanning a laser beam across ocular tissue at the subsequent placement within the eye in accordance with the subsequent treatment pattern to thereby photo disrupt the subsequent volume of ocular tissue.

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24-11-2022 дата публикации

LASER EYE SURGERY LENS FRAGMENTATION

Номер: US20220370245A1
Принадлежит:

A laser eye surgery system includes a laser to generate a laser beam. A spatial measurement system generates a measurement beam and measure a spatial disposition of an eye. A processor is coupled to the laser and the spatial measurement system, the processor comprising a tangible medium embodying instructions to determine a spatial model of the eye in an eye coordinate reference system based on the measurement beam. The spatial model is mapped from the eye coordinate reference system to a machine coordinate reference system. A laser fragmentation pattern is determined based on a plurality of laser fragmentation parameters. The laser fragmentation pattern and the spatial model is rotated by a first rotation angle such that the spatial model is aligned with the reference axis of the machine coordinate reference system and the rotated laser fragmentation pattern is aligned with the corneal incision. 117.-. (canceled)18. A method of treating an eye with a laser beam , comprising:measuring a plurality of characteristics of the eye by an eye sensor;determining a model of the eye based on the measured characteristics;receiving a rotation angle of an incision relative to a reference coordinate space;generating a laser fragmentation pattern for treating the eye;rotating the laser fragmentation pattern by the received rotation angle relative to the reference coordinate space; andapplying a laser beam by a laser source to a lens of the eye based on the rotated laser fragmentation pattern.19. The method of claim 18 , wherein the model is aligned with the reference coordinate space and the rotated laser fragmentation pattern is aligned with the incision.20. A method of treating an eye with a lens fragmentation pattern claim 18 , comprising:measuring a plurality of characteristics of an eye by a laser surgery system;determining a spherical model of the eye based on the measured characteristics;determining lens segmentation boundaries based on the spherical model;receiving a ...

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29-12-2022 дата публикации

Method for controlling an eye surgical laser, treatment apparatus, computer program as well as computer-readable medium

Номер: US20220409434A1
Принадлежит: Schwind Eye Tech Solutions GmbH

The invention relates to a method for controlling an eye surgical laser ( 18 ) for removing a volume body ( 12 ) from a cornea ( 44 ) with an anterior interface ( 16 ) of the cornea ( 44 ) and a posterior interface ( 14 ) of the cornea ( 44 ), comprising the steps of: presetting the posterior actual interface ( 14 ); determining a first imaging point ( 48 ) of the cornea ( 44 ); determining an anterior target interface ( 46 ) depending on the posterior actual interface ( 14 ) and the first imaging point ( 48 ) based on a mathematical model (M); determining a shape of the volume body ( 12 ) to be generated by presetting the determined anterior target interface ( 46 ); and generating control data for generating the volume body ( 12 ) such that the anterior actual interface ( 16 ) corresponds to the determined anterior target interface ( 46 ) after removing the volume body ( 12 ) from the cornea ( 44 ). Further, the invention relates to a treatment apparatus ( 10 ), to a computer program product as well as to a computer-readable medium.

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22-12-2021 дата публикации

Integrated ophthalmic surgery system

Номер: JP6985370B2

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03-10-2002 дата публикации

Apparatus and method for shrinking collagen

Номер: US20020143322A1
Автор: Ali Haghighi
Принадлежит: SUNRISE TECHNOLOGIES INTERNATIONAL Inc

The present invention provides a device, a system, and associated methods for advantageously treating bodily tissues containing collagen, such as the cornea. The device is a topical device that, when placed over the target tissue, defines a space between an inner surface of the device and the tissue. The radiation-transparent device allows radiation to pass therethrough to the tissue during the radiation treatment. The device is believed to reduce heat loss, such as evaporative heat loss, from the tissue, thereby improving the tissue-heating efficiency of the radiation treatment. Typical radiation treatment parameters may thus be adjusted to provide a more gentle, yet highly efficient treatment using the inventive device. The gentle treatment reduces the likelihood of thermally traumatizing the treated tissue. While the invention has particular application in the area of corneal treatment, it may be used to prepare other tissues or substrates.

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09-03-2021 дата публикации

Laser induced collagen crosslinking in tissue

Номер: US10940042B2
Принадлежит: Columbia University of New York

The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage or cornea, without using a photosensitizer (e.g., riboflavin), by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of tissue. In an embodiment, the femtosecond laser operates in the infrared frequency range.

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23-12-2003 дата публикации

Integrated wavefront-directed topography-controlled photoablation

Номер: US6666857B2
Автор: Robert F. Smith
Принадлежит: Robert F. Smith

A system and method combining wavefront analysis with narrow-beam scanning photoablation where optimal corneal topography is first calculated then followed by real-time topographic feedback controlled photoablation. Eye movement and beam position sensing to within a tolerance of 5 μm are provided by high speed digital computation in conjunction with specialized charge coupled devices. Lasers of three different wavelengths—one low-powered pulsed ultraviolet, a second continuous visible band type, and a pulsed infrared type are combined together into narrow beams whereupon a scanning mechanism generates coaxial collimated beams for the functions of ablation, beam position sensing, and fundus spot imaging. Transepithelial ablation is performed utilizing the same CCD used for wavefront analysis by switching between two dichroic mirrors. The light source for the raster videokeratography topography means is the UV laser used for ablation.

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09-08-2017 дата публикации

Intra-surgical image of optical coherent tomography cataract removal surgery

Номер: RU2627605C2
Принадлежит: Алькон Ленскс, Инк.

FIELD: medicine. SUBSTANCE: surgical system for cataract removal contains a laser source designed to form the first group of laser pulses; a guide optic coupled to the laser source configured to direct the first group of laser pulses to the target cataract area of the eye; a laser controller; an Optical Coherence Tomography Spectral Area (OCT SA) imaging system configured to create an image comprising portions of the first photocleavable region with image resolution in the range of 0.5 to 5 million pixels per image and transmission rate in the range of 20 to 200 frames per second. In this case, the laser controller is configured to generate an electronic image of the target scanning pattern and the changed scanning pattern with respect to the image generated by the OCT-SA image system; and to control the guide optic for scanning by the first group of laser pulses according to a portion of the target scanning pattern to create the firstphoto-degradable region in the target cataract region and for scanning by the second group of laser pulses according to a modified scanning pattern to create the second photodegradable region. EFFECT: extended range of technical means. 19 cl, 11 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 627 605 C2 (51) МПК A61F 9/008 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2014129807, 19.12.2012 (24) Дата начала отсчета срока действия патента: 19.12.2012 Дата регистрации: (73) Патентообладатель(и): АЛЬКОН ЛЕНСКС, ИНК. (US) Приоритет(ы): (30) Конвенционный приоритет: 19.12.2011 US 13/329,529 (56) Список документов, цитированных в отчете о поиске: US 20110196350 A1, 11.08.2011. WO 2010075571 A2, 01.07.2010. US 20090177189 A1, 09.07.2009. US 20070291277 A1, 20.12.2007. RU 2436135 C2, 10.12.2011. (45) Опубликовано: 09.08.2017 Бюл. № 22 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 21.07.2014 (86) Заявка PCT: US 2012/070434 (19.12.2012) (87) Публикация заявки PCT ...

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18-06-2021 дата публикации

Femtosecond laser real-time dynamic positioning focusing system and method

Номер: CN112587302B
Автор: 周辉
Принадлежит: Individual

本发明涉及飞秒激光实时动态定位聚焦系统及方法,采用两种光学相干成像系统对全眼的三维图像信息进行实时采集,以能够实现对飞秒脉冲激光光束精准的实时动态定位聚焦,并能够对由飞秒脉冲激光光束诱导发出的飞秒激光诱导等离子体光信号进行分析处理,进一步判断飞秒脉冲激光光束在眼组织的实时定位信息,提高了飞秒脉冲激光光束的实时动态定位聚焦的精确度。本发明的所述飞秒激光实时动态定位聚焦系统构成一个动态循环的测量和调节系统,能够实时测量和动态调节飞秒脉冲激光光束在眼组织的聚焦位置,确保手术进行过程中的安全性和精确度。

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15-03-2022 дата публикации

Systems and methods for laser surgical and therapeutic eye treatments

Номер: RU2766775C2
Принадлежит: ЭннМари ХИПСЛЕЙ

FIELD: medical equipment. SUBSTANCE: system and method for delivering microporous medical treatments to improve biomechanics are provided, wherein the system includes a laser for generating a laser beam on the treatment axis that is not aligned with the patient’s visual axis, made with the possibility of being used in subsurface ablative medical treatments to create a matrix structure of micropores that improves biomechanics. The matrix structure of micropores is at least one of a radial structure, a spiral structure, a phyllotactic structure, or an asymmetric structure. EFFECT: providing a system for the eye treatment. 26 cl, 41 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 766 775 C2 (51) МПК A61B 18/20 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК A61B 18/20 (2021.02); A61B 18/20 (2021.08) (21)(22) Заявка: 2019134801, 31.03.2018 (24) Дата начала отсчета срока действия патента: (73) Патентообладатель(и): ХИПСЛЕЙ, ЭннМари (US) Дата регистрации: 15.03.2022 Приоритет(ы): (30) Конвенционный приоритет: 31.03.2017 US 62/480,294 (43) Дата публикации заявки: 30.04.2021 Бюл. № 13 (45) Опубликовано: 15.03.2022 Бюл. № 8 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 31.10.2019 2 7 6 6 7 7 5 (56) Список документов, цитированных в отчете о поиске: US 20140316388 A1, 23.10.2014. RU 2539991 C2, 27.01.2015. R U 31.03.2018 (72) Автор(ы): ХИПСЛЕЙ, ЭннМари (US) US 2018/025608 (31.03.2018) C 2 C 2 (86) Заявка PCT: (87) Публикация заявки PCT: R U 2 7 6 6 7 7 5 WO 2018/183987 (04.10.2018) Адрес для переписки: 129090, Москва, ул. Б.Спасская, 25, строение 3, ООО "Юридическая фирма Городисский и Партнеры" (54) СИСТЕМЫ И СПОСОБЫ ДЛЯ ЛАЗЕРНЫХ ХИРУРГИЧЕСКИХ И ТЕРАПЕВТИЧЕСКИХ ЛЕЧЕНИЙ ГЛАЗ (57) Реферат: Группа изобретений относится к медицинской подповерхностных абляционных медицинских технике. Обеспечены система и способ для лечениях для создания матричной структуры доставки микропорационных медицинских микропор, ...

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24-01-2013 дата публикации

Manifest refraction treatment systems and methods

Номер: WO2013013175A1
Автор: Michael Brownell
Принадлежит: AMO Development, LLC.

Embodiments of the present invention encompass systems and techniques for developing a vision prescription for a patient based on an objective optical manifest refraction, such as that measured with a wavefront device, without altering the prescription in response to any subjective manifest refraction, such as that measured with a phoropter device.

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11-12-2020 дата публикации

Laser method and system for resolving, mitigating, and reversing presbyopia

Номер: CN112074252A
Принадлежит: Lensar Inc

提供用于执行激光操作以增加眼睛的调节幅度的系统和方法。用于眼睛的晶状体中的结构性柱以使得毗邻柱的晶状体的受激光影响区域变形的系统方法以及激光传送图案和操作。

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19-02-2018 дата публикации

Precise fixation of surgical photo-disruption objective

Номер: ES2655204T3
Принадлежит: Alcon Lensx Inc

Un sistema de cirugía láser, que comprende: i. un láser de impulsos (1010; 2130; 9100) para producir un rayo láser de impulsos láser; ii. un módulo óptico (1020; 2140; 4100; 5100/5200/5600; 6410/6420/6430/6440/5600/7100) configurado para recibir el rayo láser, para enfocar y dirigir el rayo láser a un tejido objetivo, donde el tejido objetivo es la lente de un ojo, para producir una foto-disrupción de la lente; y para escanear el rayo láser sobre un rango profundidad de escaneo del sistema quirúrgico, que abarca la distancia desde el epitelio a la lente del cristalino del ojo; iii. una placa de aplanación (2150; 2240; 3300; 4200) utilizada para que esté en contacto con el ojo para producir una interfaz y para emitir impulsos láser al objetivo y transmitir luz o sonido reflejado o disperso del objetivo a través de la interfaz; iv. un dispositivo de visualización de tomografía de coherencia óptica (TCO) (1030; 2200; 2230/4100; 5300) configurado para dirigir la luz de TCO y capturar la luz de TCO reflejada de la lente del ojo, y para crear una imagen en donde la distancia entre la lente y la córnea se puede identificar; y v. un módulo de control del sistema (1040; 2120; 3100; 6100; 9200) configurado para procesar información de visualización de la imagen a partir del dispositivo de visualización y para controlar el módulo óptico para ajustar el enfoque del rayo láser sobre la lente del ojo en base a la información de visualización, en donde el módulo óptico comprende un escáner de rayos láser quirúrgicos ubicado en un trayecto óptico del rayo láser para escanear el rayo láser quirúrgico sin escanear la luz de TCO, caracterizada por que el dispositivo de visualización de TCO incluye un segundo escáner de rayos. A laser surgery system, comprising: i. a pulse laser (1010; 2130; 9100) to produce a laser pulse laser beam; ii. an optical module (1020; 2140; 4100; 5100/5200/5600; 6410/6420/6430/6440/5600/7100) configured to receive the laser beam, to focus and direct the ...

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15-11-2016 дата публикации

Imaging surgical target tissue by nonlinear scanning

Номер: US9492322B2
Принадлежит: Alcon Lensx Inc

Systems and techniques for laser surgery based on imaging a target tissue by nonlinear scanning are presented. In one implementation, a method for guiding an eye surgery can include the steps of: positioning an eye in relation to an imaging system; creating first scan data by determining a depth of an eye target region at a first set of points along a first arc; creating second scan data by determining a depth of the eye target region at a second set of points along a second arc; determining target region parameters based on the first and second scan data; and adjusting one or more surgical position parameters according to the determined target region parameters.

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30-06-2015 дата публикации

Intra-surgical optical coherence tomographic imaging of cataract procedures

Номер: US9066784B2
Принадлежит: Alcon Lensx Inc

A cataract surgical system includes a laser source to generate a first set of laser pulses; a guiding optic to guide the first set of laser pulses to a cataract target region in an eye; a laser controller to generate an electronic representation of a target scan pattern, and to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the cataract target region; and a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system to generate an image of a portion of the first photo-disrupted region. The laser controller can generate an electronic representation of a modified scan pattern in relation to the image generated by the SD-OCT imaging system, and control the guiding optic to scan a second set of laser pulses according the modified scan pattern.

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