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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 3239. Отображено 100.
01-03-2012 дата публикации

Flow regulating implant, method of manufacture, and delivery device

Номер: US20120053505A1
Автор: Ira Yaron, Orit Yarden
Принадлежит: Optonol Ltd

An implant includes a tube for permitting fluid flow. A flow controlling rod may be inserted within the tube passage. One or more holes around the circumference of the tube may be selectively permanently or temporarily occluded to give desired flow characteristics. A delivery device for implanting the implant may include a central bore in which a retractable wire is located. The retractable wire penetrates a tube passage of the implant. After the implant is in position in the eye, the retention wire is retracted out of the implant. In a method for manufacturing an implant, two tubes of different diameters are utilized. The smaller tube fits inside the longitudinal bore of the larger tube. When the tubes are cut, the smaller tube forms the tube of the implant and the remaining portions of the larger tube form the retention projection and/or disk of the implant.

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Номер записи: 1
05-04-2012 дата публикации

Annular and other ablation profiles for refractive surgery systems and methods

Номер: US20120083776A1
Автор: Guang-Ming Dai, Michael Brownell
Принадлежит: AMO DEVELOPMENT LLC

Systems, methods, and computer program products are provided for the administration of annular and other ablation profiles during refractive surgery treatments. Basis data framework techniques enable the implementation of both circular and annular ablation profiles resulting in increased ablation efficiency when treating certain vision conditions. In some instances, systems or treatments involve the use of symmetric and asymmetric ablations shapes such as double spots, triple spots, quadruple spots, multiple spots, arc shapes, elliptical shapes, and the like.

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Номер записи: 2
17-05-2012 дата публикации

Methods for deploying intraocular shunts

Номер: US20120123433A1
Автор: Christopher Horvath, Guenther Grabner, Herbert A. Reitsamer, Laszlo O. Romoda
Принадлежит: Aquesys Inc

The present invention generally relates to methods for deploying intraocular shunts without the use of an optical apparatus that contacts an eye, such as a goniolens. In certain embodiments, methods of the invention involve inserting into an eye a deployment device configured to hold an intraocular shunt, determining that a distal portion of the device is properly positioned within the eye without use of an optical apparatus that contacts the eye, and deploying the shunt from the device.

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Номер записи: 3
14-06-2012 дата публикации

Laser device, in particular, for ophthalmological laser surgery

Номер: US20120150156A1
Автор: Daniel Thürmer, Mathias Wölfel, Olaf Kittelmann
Принадлежит: Olaf Kittelmann, Thuermer Daniel, Wõlfel Mathias

A laser device, in particular for ophthalmological laser surgery, comprising a laser source ( 14 ) for providing laser radiation, controllable scan components ( 20 ) for setting a focus position of the laser radiation, measuring components ( 30 ) for registering information that is representative of an actual position of the radiation focus, and also a control arrangement ( 22 ) controlling the laser source and the scan components. In accordance with the invention, the control arrangement has been set up to bring about the implementation of a test-mode operation of at least some of the scan components with the laser source turned off, in accordance with a predetermined test scan pattern, the test scan pattern defining at least one scan path for the radiation focus, and the control arrangement having been set up to bring about, during a scan movement along the scan path, repeatedly in succession a registration of the actual focus position without stopping the scan movement, and to ascertain a desired focus position, assigned to each registered actual focus position.

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Номер записи: 4
14-06-2012 дата публикации

Laser device for ophthalmological laser surgery

Номер: US20120150157A1
Автор: Daniel Thürmer, Mathias Wölfel, Olaf Kittelmann
Принадлежит: Olaf Kittelmann, Thuermer Daniel, Wõlfel Mathias

A laser device, in particular for ophthalmological laser surgery, comprising a laser source ( 14 ) for providing laser radiation, controllable scan components ( 20 ) for setting a focus position of the laser radiation, measuring components ( 30 ) for registering information that is representative of an actual position of the radiation focus, and also a control arrangement ( 22 ) controlling the laser source and the scan components. In accordance with the invention, the control arrangement can be set up to bring about the implementation of a test-mode operation of at least some of the scan components with the laser source turned off, in accordance with a predetermined test scan pattern, the test scan pattern representing a plurality of discrete desired focus positions to be traversed in succession, and the control arrangement having been set up to stop, at each of the desired focus positions, the scan movement of the scan components and to ascertain, assigned to each of the desired focus positions, respectively an actual focus position on the basis of the registered information of the measuring components.

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Номер записи: 5
09-08-2012 дата публикации

Device for ophthalmological laser surgery

Номер: US20120203215A1
Автор: Christof Donitzky, Peter Riedel
Принадлежит: WaveLight GmbH

An apparatus for ophthalmic laser surgery includes a contact surface for shaping abutment of an eye to be treated, a first radiation-source for making a treatment laser beam available, optical components for directing the treatment laser beam through the contact surface onto the eye and also a measuring device for measuring at least one corneal thickness dimension or/and positional dimension of the eye bearing against the contact surface, whereby the measuring device makes measured data available that are representative of the measured at least one thickness dimension or/and positional dimension. The measuring device preferably serves for positional surveying of the corneal posterior surface of the eye, whereby an electronic evaluating and control arrangement connected to the measuring device brings about a focus control of the treatment laser beam in a manner depending on the measured position of the posterior surface of the cornea.

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Номер записи: 6
18-10-2012 дата публикации

Altering Iris Color

Номер: US20120265180A1
Автор: Gregg S. Homer
Принадлежит: Stroma Medical Corp

Techniques for altering iris pigment in a human or animal, thereby altering iris color of an iris from a first iris color to a second iris color, are provided. An apparatus includes at least one laser device and a masking device. Another apparatus includes at least one laser device and a contact lens. The at least one laser device can generate at least one beam to selectively remove iris pigment of at least one preselected pigment color from the iris.

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Номер записи: 7
25-10-2012 дата публикации

Accommodation compensation systems and methods

Номер: US20120271413A1
Автор: Guang-Ming Dai, Leander Zickler
Принадлежит: AMO DEVELOPMENT LLC

Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

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Номер записи: 8
22-11-2012 дата публикации

Optical devices and methods for selective and conventional photocoagulation of the retinal pigment epithelium

Номер: US20120296320A1
Автор: Charles P. Lin, Clemens Alt
Принадлежит: General Hospital Corp

The present invention provides devices and methods for applying radiation to the retina of a patient. In one embodiment, an apparatus includes a radiation source for generating a radiation beam suitable for absorption by retinal pigment epithelial cells. One or more optical components are included to direct the beam onto the retina. A scanner is optically coupled to the radiation source to control movement of the beam in two dimensions to allow a scan over the retina. A controller applies control signals to the scanner to adjust beam movement to illuminate a plurality of retinal locations in a temporal sequence according to a predefined pattern. The device can be operated in one mode to effect selective targeting of retinal pigment epithelial cells, or in another mode to effect thermal photocoagulation of the retina.

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Номер записи: 9
21-03-2013 дата публикации

Conformable Therapeutic Shield for Vision and Pain

Номер: US20130070200A1
Автор: Ashley Tuan, Brian Levy, Cary J. Reich, Dean Carson, Doug Rimer, Douglas Sutton, Enrique Barragan, Eugene de Juan, Jr., K. Angela Macfarlane, Matt Clarke, Yair Alster
Принадлежит: Nexis Vision Inc

A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

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Номер записи: 10
25-04-2013 дата публикации

System and Method for Lowering IOP by Creation of Microchannels in Trabecular Meshwork Using a Femtosecond Laser

Номер: US20130103011A1
Автор: David Haydn Mordaunt, Robert Edward Grant
Принадлежит: Individual

A system and its method for creating a microchannel in the trabecular meshwork of an eye include a laser unit for generating a laser beam, and an imaging unit for creating an image of the trabecular meshwork. The system also includes a computer which defines the microchannel. A comparator that is connected with the computer then controls the laser unit to move the focal point of the laser beam. This focal point movement is accomplished to create the microchannel, while minimizing deviations of the focal point from the defined microchannel.

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Номер записи: 11
25-04-2013 дата публикации

Methods and patterns for increasing amplitude of accommodations in a human lens

Номер: US20130103013A1
Автор: Andrew A. Esposito
Принадлежит: NUSITE Tech LLC

A method of treating a human eye, generally to correct vision, and preferably in one embodiment to increase the amplitude of accommodation of the lens. The method utilizes a laser to create a desired pattern within the lens. Various patterns for treating the eye lens are also disclosed.

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Номер записи: 12
25-04-2013 дата публикации

Patient interface for ophthalmologic diagnostic and interventional procedures

Номер: US20130103014A1
Автор: Michael Wiltberger, Philip Gooding
Принадлежит: Optimedica Corp

An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.

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Номер записи: 13
06-06-2013 дата публикации

Device for processing eye tissue by means of a pulsed laser beam

Номер: US20130144277A1
Автор: Christian Rathjen, Hartmut Kanngiesser, Lorenz Klauser, Vincent Ducry
Принадлежит: SIE Surgical Instrument Engineering AG

For processing eye tissue using a pulsed laser beam (L), an ophthalmological device includes a projection optical unit for the focused projection of the laser beam (L) into the eye tissue, and a scanner system upstream of the projection optical unit for the beam-deflecting scanning of the eye tissue with the laser beam (L) in a scanning movement (s′) performed over a scanning angle along a scanning line (s). The ophthalmological device includes a divergence modulator upstream of the scanner system for dynamically varying the divergence of the laser beam (L), whereby the scanning line (s) is tilted in a plane running through the optical axis of the projection optical unit and the scanning line(s). The tilting of the scanning line(s) enables a displacement—dependent on the scanning angle—of the focus of the laser pulses projected into the eye tissue without vertical displacement of the projection optical unit.

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Номер записи: 14
06-06-2013 дата публикации

Devices and Methods for Multispot Scanning

Номер: US20130144278A1
Автор: John Christopher Huculak, Michael J. Yadlowsky, Michael Papac
Принадлежит: Alcon Research LLC

An ophthalmic endoprobe system comprises an optical fiber configured to transmit light energy along an optical axis. The system further comprises a first scanning element rotatable relative to the optical fiber and arranged to receive at least a portion of the transmitted light energy. The first scanning element includes a diffractive optical element. The system also comprises a second scanning element rotatable relative to the first scanning element and arranged to receive at least a portion of the transmitted light energy from the first scanning element.

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Номер записи: 15
13-06-2013 дата публикации

Device for processing eye tissue by means of a pulsed laser beam

Номер: US20130150837A1
Автор: Christian Rathjen, Hartmut Kanngiesser, Lorenz Klauser, Vincent Ducry
Принадлежит: SIE Surgical Instrument Engineering AG

For processing eye tissue by means of a pulsed laser beam (L), an ophthalmological device comprises a projection optical unit for the focused projection of the laser beam (L) into the eye tissue, and a scanner system disposed upstream of the projection optical unit and serving for the beam-deflecting scanning of the eye tissue with the laser beam (L) in a scanning movement (s′) performed over a scanning angle along a scanning line (s). The projection optical unit can be tilted about an axis of rotation (q) running perpendicularly to a plane defined by the scanning line (s) and the optical axis (o) of the projection optical unit, the tilting of the projection optical unit bringing about a tilting of the scanning line (s) in said plane. The tilting of the scanning line (s) enables a displacement—dependent on the scanning angle—of the focus of the laser pulses projected into the eye tissue without vertical displacement of the projection optical unit.

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Номер записи: 16
25-07-2013 дата публикации

Systems and methods for correcting high order aberrations in laser refractive surgery

Номер: US20130190736A1
Автор: Anatoly Fabrikant, Ben Logan, David Hindi, Dimitri Chernyak, Guang-Ming Dai, Qi Wang
Принадлежит: AMO Manufacturing USA LLC

Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.

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Номер записи: 17
29-08-2013 дата публикации

Apparatus for treating eye tissue with laser pulses

Номер: US20130226160A1
Автор: Christian Rathjen
Принадлежит: Ziemer Ophthalmic Systems AG

An ophthalmological apparatus ( 1 ) for treating eye tissue ( 3 ) with laser pulses (P) comprises a laser source ( 100, an optical projection system ( 20 ) for projecting the laser pulses (P) onto the eye tissue ( 30 ), and a coupling part ( 12 ) for attaching mechanically to the optical projection system ( 20 ) an ophthalmological patient interface device ( 27 ) which is in contact with the eye ( 3 ) during treatment. The ophthalmological apparatus ( 1 ) further comprises a detector ( 13 ) for determining a device identifier ( 22 ) associated with the ophthalmological patient interface device ( 27 ), and a control module ( 14 ) for controlling the ophthalmological apparatus ( 1 ) using the device identifier ( 22 ). The detector makes it possible to use and detect different types of ophthalmological patient interface devices ( 27 ) and to adapt automatically the treatment of the eye tissue ( 30 ), depending on the ophthalmological patient interface device ( 27 ) that is presently attached to the ophthalmological apparatus ( 1 ).

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Номер записи: 18
26-09-2013 дата публикации

Methods for deploying intraocular shunts

Номер: US20130253406A1
Автор: Christopher Horvath, Guenther Grabner, Herbert A. Reitsamer, Laszlo O. Romoda
Принадлежит: Aquesys Inc

The present invention generally relates to methods for deploying intraocular shunts without the use of an optical apparatus that contacts an eye, such as a goniolens. In certain embodiments, methods of the invention involve inserting into an eye a deployment device configured to hold an intraocular shunt, determining that a distal portion of the device is properly positioned within the eye without use of an optical apparatus that contacts the eye, and deploying the shunt from the device.

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Номер записи: 19
03-10-2013 дата публикации

Adjustable Valve For IOP Control With Reed Valve

Номер: US20130261530A1
Автор: Satish Yalamanchili
Принадлежит: Alcon Research LLC

A drainage device for implantation in an eye of a patient to treat an ocular condition, that includes an implant body portion comprising of a valve portion. The valve portion may comprise a flexible membrane disposed and arranged in a manner to affect flow of aqueous humor through the implant body portion. The device may also include a reed valve disposed downstream of the flexible membrane. The reed valve may be configured to prevent backflow of aqueous humor toward the membrane and configured to stabilize flow by affecting pressure at the flexible membrane. In one aspect, the reed valve is configured to create backpressure at the membrane that affects the rate of flow at the flexible membrane.

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Номер записи: 20
17-10-2013 дата публикации

Device and process for machining the human eye using laser technology

Номер: US20130274723A1
Автор: Christian Wüllner, Christof Donitzky, Jorg Klenke
Принадлежит: WaveLight GmbH

A device for machining the human cornea with focused laser radiation includes controllable components for setting the location of the radiation focus, a control computer for controlling these components, and also a control program for the control computer. The control program contains instructions that have been designed to bring about, upon execution by the control computer, the generation of incisions in the cornea in accordance with a predetermined incision figure, the incision figure defining a corneal bed, a flap situated on the bed and also at least one tissue strip situated in the region of the peripheral edge of the flap between the bed and the flap and extending along the edge of the flap. After the flap has been folded away, the tissue strip has to be removed and enables a creaseless post-ablative close fitting of the folded-back flap against the surface of the bed. In this manner, microstriae which may impair the visual capacity can be avoided.

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Номер записи: 21
19-12-2013 дата публикации

Ophthalmology

Номер: US20130335703A1
Автор: Andrew Fogg, Christopher David Creasey, Stuart Brian Milne
Принадлежит: Optos Plc

Apparatus for illuminating the retina of an eye. The apparatus comprising an illumination device, a lens system, wherein the illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus further comprising an illumination transfer device, wherein the illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device, and wherein the illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.

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Номер записи: 22
19-12-2013 дата публикации

NONLINEAR OPTICAL PHOTODYNAMIC THERAPY (NLO-PDT) OF THE CORNEA

Номер: US20130338650A1
Автор: Brown Donald J., Chai Dongyui, Jester James V., Juhasz Tibor, Winkler Moritz
Принадлежит: The Regents of the University of California

The embodiments include method of nonlinear optical photodynamic therapy of tissue including the steps of providing pulsed infrared laser light for two-photon excited fluorescence tissue exposure, and selectively focusing the pulsed infrared laser light within the tissue at a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. The invention is also directed to an apparatus for performing nonlinear optical photodynamic therapy of tissue including a pulsed infrared laser for providing two-photon excited fluorescence beam tissue exposure, a scanner for selectively and controllably moving the tissue and the beam relative to each other, and optics for selectively focusing the pulsed infrared laser light within the tissue at a point in a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. 1. A method of nonlinear optical photodynamic therapy of tissue comprising:providing a focal spot of a pulsed infrared laser light for multiphoton tissue exposure through a focusing lens, the focal spot having a volume and the focusing lens having an effective numerical aperture;selectively, repetitively and three dimensionally positioning the focal spot in the tissue in a selected volume of the tissue larger than the volume of the focal spot to expose the selected volume of tissue to the pulsed infrared laser light within a predetermined clinical time span; andwhere providing the focal spot provides the focal spot with a selected focal volume and predetermined safe intensity sufficient to activate a photosensitizing agent in the tissue in the volume of tissue to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue by utilizing the predetermined safe intensity of the focal spot and by adjusting the volume of the focal spot of the pulsed infrared laser light ...

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Номер записи: 23
09-01-2014 дата публикации

Restoration of accommodation by lens refilling

Номер: US20140012240A1
Автор: Arthur Ho, Jean-Marie Parek, Jukka MOILANEN, Paul Mendell Erickson
Принадлежит: Individual

A method for refilling a lens of an eye or increasing the elasticity of a lens of an eye includes removing a central portion of the lens core through the eye's cornea, a capsulorhexis in the eye's lens capsule and a gullet extending at least partially through the cortex of the lens. The lens is then refilled with a synthetic lens material. Sufficient lens core is left in place so that the synthetic material is not in contact with a lens capsule of the eye. The synthetic material used for refilling may be selected and may be formed in a shape and thickness so as to affect the refractive characteristics of the lens. An endocapsular lenticule may be inserted in the lens to affect the refractive characteristics of the lens.

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Номер записи: 24
13-02-2014 дата публикации

Laser-Assisted Thermal Separation of Tissue

Номер: US20140046310A1
Автор: David H. Mordaunt
Принадлежит: EOS Holdings LLC

A laser-assisted method for fully or partially separating tissue such as collagen-containing tissue is provided. In one embodiment, the method pertains to a capsolurorhexis whereby the laser-assisted method is applied to the lens capsule. A light-absorbing agent is added into or onto the tissue. A light beam with a wavelength capable of being absorbed by the light absorbing agent is then directed at the tissue to cause a thermal effect at the tissue following a predetermined closed curve with the goal to avoid irregularity- or potential tears in the resulting rim of the tissue.

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Номер записи: 25
06-03-2014 дата публикации

System and apparatus for delivering a laser beam to the lens of an eye

Номер: US20140066906A9
Автор: Gary P. Gray, George R. Downes, Jr., Jerome R. Kuszak, Jorge A. De Castro, Neil Zepkin, Richard Ty Olmstead, Rudolph W. Frey
Принадлежит: Lensar Inc

A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided a range determining system for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.

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Номер записи: 26
10-04-2014 дата публикации

Method and Systems for Laser Treatment of Presbyopia Using Offset Imaging

Номер: US20140100556A1
Автор: Charles R. Munnerlyn, Jerome A. Legerton, John K. Shimmick, Kenneth Greenberg, Marc Odrich
Принадлежит: AMO Manufacturing USA LLC

An ophthalmic surgery system and method for treating presbyopia by performing ablative photodecomposition of the corneal surface. The offset image of a variable aperture, such as a variable width slit and variable diameter iris diaphragm, is scanned in a preselected pattern to perform ablative sculpting of predetermined portions of a corneal surface. The scanning is performed to ablate an optical zone sized to match the patient pupil with a peripheral transition zone outside the pupil. The shape of the ablated optical zone is different from the shape of the final optical correction on the anterior surface of the cornea. The optical zone corrects for near-vision centrally and far-vision peripherally. A movable image displacement mechanism enables radial displacement and angular rotation of the profiled beam exiting from the variable aperture. The invention enables wide area treatment with a laser having a narrower beam than the treatment area, and can be used in the treatment of many conditions in conjunction with presbyopia such as hyperopia, hyperopic astigmatism and irregular refractive aberrations.

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Номер записи: 27
07-01-2021 дата публикации

COMPACT ULTRA-SHORT PULSED LASER EYE SURGERY WORKSTATION

Номер: US20210000649A1
Автор: Fu Hong, Moore Bryant M., Vice Charles
Принадлежит:

A compact system for performing laser ophthalmic surgery is disclosed. An embodiment of the system includes a mode-locked fiber oscillator-based ultra-short pulsed laser capable of producing laser pulses in the range of 1 nJ to 5 μJ at a pulse repetition rate of between 5 MHz and 25 MHz, a resonant optical scanner oscillating at a frequency of 200 Hz and 21000 Hz, a scan-line rotator, a movable XY-san device, a z-scan device, and a controller configured to coordinate with the other components of the system to produce one or more desired incision patterns. The system also includes compact visualization optics for in-process monitoring using a beam-splitter inside the cone of a patient interface used to fixate the patient's eye during surgery. The system can be configured such that eye surgery is performed while the patient is either sitting upright, or lying on his or her back. 1. An ophthalmic surgical laser system comprising:a laser delivery system configured to deliver a pulsed laser beam at a focal point of a target in a patient's eye, the pulsed laser beam having a pulse repetition rate in the range between 5 MHz and 25 MHz;a resonant optical scanner, the scanner oscillating at a frequency between 200 Hz and 21000 Hz.an xy-scan device configured to move the pulsed laser beam in a lateral direction;a z-scan device configured to modify a depth of focus of the pulsed laser beam; anda controller operably coupled with the laser delivery system, the xy-scan device and the z-scan device, the controller configured to direct the laser delivery system to output the pulsed laser beam in a desired pattern at the focal point of the target in the eye so as to modify the target.228-. (canceled)29. An interface for coupling a patient's eye to an ophthalmic surgical laser system , the interface comprising: an apex ring coupled to the first plane surface, the apex ring comprising a distal end;', "a first receptacle configured to receive an attachment ring, the attachment ring ...

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Номер записи: 28
07-01-2016 дата публикации

LASER-ASSISTED THERMAL SEPARATION OF TISSUE

Номер: US20160000603A1
Автор: Mordaunt David H.
Принадлежит:

A laser-assisted method for fully or partially separating tissue such as collagen containing tissue is provided. In one embodiment, the method pertains to a capsulorhexis whereby the laser-assisted method is applied to the lens capsule. A light-absorbing agent is added into or onto the tissue. A light beam with a wavelength capable of being absorbed by the light absorbing agent is then directed at the tissue to cause a thermal effect at the tissue following a predetermined closed curve with the goal to avoid irregularity or potential tears in the resulting rim of the tissue. 1. A device for thermally separating tissue in the anterior lens capsule of an eye in a procedure creating an opening in the anterior lens capsule , the device comprising:a laser device programmed to direct a laser beam along a predetermined closed curve on the anterior lens capsule;wherein the laser beam power, wavelength, and diameter at the anterior lens capsule are selected such that the laser beam is absorbed by a light absorbing agent in or on the anterior lens capsule to locally heat the anterior lens capsule along the closed curve without ablation of the anterior lens capsule, thereby separating the anterior lens capsule along the closed curve to form an area of anterior lens capsule tissue inside the closed curve and an area of anterior lens capsule tissue outside the closed curve, the lens capsule tissue outside the closed curve defining the boundary of the opening in the anterior lens capsule;wherein the laser device is programmed to direct the laser beam in a single pass starting at an initial point interior to the closed curve, then along the closed curve, and then to a final point interior to the closed curve;wherein the laser beam diameter at the anterior lens capsule is 50 microns to 600 microns;wherein the laser beam power at the anterior lens capsule is less than or equal to 1000 mW;wherein the laser beam is directed along the closed curve at less than or equal to 10 ...

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Номер записи: 29
07-01-2016 дата публикации

PRESBYOPIC VISION CORRECTION WITH CONTROLLED 3-D PATTERNED MECHANICAL WEAKENING OF SCLERAL TISSUE

Номер: US20160000605A1
Автор: Grant Robert E., Mordaunt David H.
Принадлежит:

Treatments to improve ocular conditions such as presbyopia are provided. Structural (mechanical) weakening of the sclera is accomplished through the formation of a 3-D pattern of laser foci in the sclera resulting in an increase in the range of ocular accommodation. 1. A method of structurally weakening the sclera in an eye to improve a presbyopia condition of the eye , the method comprising:using a pulsed laser system to generate a three-dimensional (3-D) pattern of focused laser pulses in the sclera, the laser pulses passing noninvasively through a conjunctiva layer in the eye to a plurality of foci in the sclera to structurally weaken the sclera at the foci, thereby producing a 3-D pattern of structurally weakened regions in the sclera that increases the eye's range of ocular accommodation and improves the presbyopia condition;wherein each of the structurally weakened regions in the sclera has a 3-D ellipsoidal shape.2. The method as set forth in claim 1 , wherein the 3-D pattern of structurally weakened regions in the sclera elongates the sclera.3. The method as set forth in claim 1 , wherein the 3-D pattern of structurally weakened regions in the sclera increases the elasticity of the sclera.4. The method as set forth in claim 1 , wherein each of the 3-D ellipsoidal shapes has a minor axis of 6 micrometers to 50 micrometers and a major axis of 50 micrometers to 300 micrometers.5. The method as set forth in claim 1 , wherein each of the focused laser pulses has a pulse-width of 1 femtosecond to 500 picoseconds and a suitable peak power to ensure structural weakening of the sclera.6. The method as set forth in claim 1 , wherein each of the focused laser pulses has a pulse-width of 1 femtosecond to 500 picoseconds and a peak power in a range of 10 kW to 60 kW.7. The method as set forth in claim 1 , wherein each of the focused laser pulses has a pulse-width of 1 femtosecond to 10 nanoseconds and a suitable peak power to ensure structural weakening of the sclera.8. ...

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Номер записи: 30
02-01-2020 дата публикации

SCLERAL TRANSLOCATION ELASTO-MODULATION METHODS AND APPARATUS

Номер: US20200000634A1
Автор: HEREKAR Rajeev, HEREKAR Satish
Принадлежит: ALeyeGN Technologies LLC

A laser delivery system is configured to delivery light energy to soften and realign the tissue of the eye in order to increase accommodation and treat glaucoma. The laser system can be configured to increase a circumlental space of the eye and increase movement of a posterior vitreous zonule in order to increase accommodation. The light energy may comprise wavelengths strongly absorbed by collagen of the sclera. In many embodiments a heat sink is provided to couple to the conjunctiva and the heat sink comprises a material transmissive to the light energy absorbed by collagen, for example Zinc Selenide. The heat sink can be chilled to inhibit damage to the conjunctiva of the eye. In many embodiments, one or more layers of the epithelium of the eye remain substantially intact above the zone where the eye has been treated when the heat sink has been removed. 1. An apparatus to treat an eye , the apparatus comprising:a source of energy to soften a sclera of the eye;a processor comprising instructions to treat the eye with the source of energy in order to soften the sclera between a lens equator and an insertion of posterior zonule into an ora serrata of the eye.2. An apparatus as in claim 1 , wherein the processor comprises instructions to treat the eye with the energy source to increase a circumlental space of the eye.3. An apparatus as in claim 1 , wherein the processor comprises instructions to treat the eye with the energy source to increase movement of a posterior vitreous zonule when the eye accommodates.4. An apparatus as in claim 1 , further comprising:a cooling structure to contact an outer surface of the eye, wherein the processor comprises instructions to treat the eye with the source of energy when the cooling structure contacts the outer surface of the eye.5. An apparatus as in claim 4 , wherein the cooling structure comprises one or more of a heat sink or a chiller.6. An apparatus as in claim 5 , wherein the cooling structure comprises the heat sink ...

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Номер записи: 31
04-01-2018 дата публикации

CONVEX CONTACT PROBE FOR THE DELIVERY OF LASER ENERGY

Номер: US20180000638A1
Автор: Buzawa David, Chew Paul T.K.
Принадлежит:

Systems, devices, and methods for treating a glaucomatous eye are provided. Embodiments may provide a treatment probe for treating an eye of a patient. The treatment probe may have an elongate body with a contact surface at a distal end of the elongate body. A treatment fiber or light source may be housed in the treatment probe and may be configured to direct treatment energy from the contact surface. The contact surface may be configured to couple to a surface of the eye to deliver the energy into the target area. In many embodiments the contact surface may have a convex configuration with a rounded outer shape and edge that facilitates the sweeping of the probe surface across the eye during treatment delivery. In some embodiments the probe may be swept in arc motions while delivering treatment energy to the eye. 1. A treatment probe for treating a portion of the eye , the treatment probe comprising:an elongate body having a proximal end and a distal end; anda contact member coupled with the distal end of the elongate body, the contact member including a convex contact surface for positioning on a surface of the eye;wherein the treatment probe is configured to deliver a treatment beam to the eye in order to treat the eye.2. A method for treating a portion of an eye comprising: an elongate body having a proximal end and a distal end; and', 'a contact member coupled with the distal end of the elongate body, the contact member having a convex contact surface;, 'providing a treatment probe that includespositioning the convex contact surface of the contact member on a surface of the eye; anddelivering a treatment beam to the eye via the treatment probe. This application is a continuation of U.S. patent application Ser. No. 14/750,729 filed Jun. 25, 2015, which claims priority to and the benefit of U.S. Provisional Patent Application No. 62/018,345 filed on Jun. 27, 2014, the contents of which are incorporated herein by reference in their entirety for all purposes.The ...

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Номер записи: 32
04-01-2018 дата публикации

CORNEAL DENERVATION FOR TREATMENT OF OCULAR PAIN

Номер: US20180000639A1
Автор: Alejandro Jose D., Alster Yair, de Juan, Gifford Hanson S., JR. Eugene, Rafaeli Omer, Reich Cary J., Scholl John A., Sutton Douglas
Принадлежит:

Methods and apparatus for the treatment of the eye to reduce pain can treat at least an outer region of the tissue so as to denervate nerves extending into the inner region and reduce the pain. For example, the cornea of the eye may comprise an inner region having an epithelial defect, and an outer portion of the cornea can be treated to reduce pain of the epithelial defect. The outer portion of the cornea can be treated to denervate nerves extending from the outer portion to the inner portion. The outer portion can be treated in many ways to denervate the nerve, for example with one or more of heat, cold or a denervating noxious substance such as capsaicin. The denervation of the nerve can be reversible, such that corneal innervation can return following treatment. 1. A method of treating a cornea of an eye , comprising:applying an apparatus to an anterior surface of a cornea, wherein the cornea comprises an epithelium, a stroma, an inner portion and an outer portion; andapplying energy from the apparatus to denervate a region of the cornea corresponding to a denervation treatment profile.2. The method of claim 1 , wherein treating comprises denervating a portion of the cornea.3. The method of claim 1 , wherein treating comprises denervating an inner portion of the cornea.4. The method of claim 1 , wherein the apparatus comprises an annular ring configured to contact the cornea.5. The method of claim 1 , wherein the energy comprises radiofrequency energy claim 1 , heating claim 1 , cooling claim 1 , light claim 1 , or ultrasound.6. The method of claim 1 , wherein applying energy comprises applying energy to the outer portion according to the denervation treatment profile.7. The method of claim 1 , wherein denervating comprises severing axons in the region of the cornea.8. The method of claim 1 , wherein denervation comprises stunning corneal nerves claim 1 , increasing the threshold of the corneal nerves claim 1 , inhibiting corneal nerve transmission claim 1 , ...

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Номер записи: 33
04-01-2018 дата публикации

STEERABLE LASER PROBE

Номер: US20180000644A1
Автор: Raney Justin M., Scheller Gregg D., Zeid Matthew N.
Принадлежит: KATALYST SURGICAL, LLC

A steerable laser probe may include a handle having a handle distal end and a handle proximal end, an actuation control of the handle, a housing tube having a housing tube distal end and a housing tube proximal end, a first housing tube portion having a first stiffness, a second housing tube portion having a second stiffness, an optic fiber disposed within an inner portion of the handle and the housing tube, and a cable disposed within the housing tube and the actuation control. A rotation of the actuation control may be configured to gradually curve the housing tube and the optic fiber. A rotation of the actuation control may be configured to gradually straighten the housing tube and the optic fiber. 1. A laser probe comprising:a handle having a handle distal end and a handle proximal end;an actuation control having an actuation control distal end, an actuation control proximal end, an actuation control anterior end, and an actuation control posterior end wherein the actuation control is disposed in an inner portion of the handle;an actuation chamber of the actuation control;a housing tube having a housing tube distal end and a housing tube proximal end wherein a portion of the housing tube is disposed in the handle;a first housing tube portion of the housing tube having a first stiffness;a plurality of apertures of the first housing tube portion;a second housing tube portion of the housing tube having a second stiffness wherein the second stiffness is greater than the first stiffness; andan optic fiber having an optic fiber distal end and an optic fiber proximal end wherein the optic fiber is disposed in the housing tube, the inner portion of the handle, and the actuation control and wherein a rotation of the actuation control in a first direction is configured to curve the optic fiber and wherein the actuation chamber is configured to prevent a contact between a portion of the actuation control and a portion of the optic fiber.2. The laser probe of wherein the ...

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Номер записи: 34
04-01-2018 дата публикации

PATIENT INTERFACE FOR OPHTHALMOLOGIC DIAGNOSTIC AND INTERVENTIONAL PROCEDURES

Номер: US20180000646A1
Автор: Beltran Christine, Gooding Phillip, Talamo Jonathan, Wiltberger Michael
Принадлежит:

An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device. 127.-. (canceled)28. A system for ophthalmic intervention on an eye of a patient having temporary geometric markers thereon indicative of the orientation of an astigmatic axis of the patient's eye , comprising:a. an imaging device having a field of view oriented toward the eye of the patient, the imaging device configured for generating 3-dimensional images of the field of view;b. a patient interface housing having proximal and distal ends and defining a passage therethrough, wherein the distal end is coupled to one or more seals around a periphery of the passage configured to be directly engaged with an exterior surface of the eye of the patient and having a size sufficient to render visible the temporary geometric markers on the eye in that the temporary geometric markers are within the field of view of the imaging device, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage;c. three or more registration fiducials formed on an inner annulus of the patient interface housing ...

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Номер записи: 35
04-01-2018 дата публикации

LENTICULAR LASER INCISION FOR LOW MYOPIA AND/OR HYPEROPIA PATIENTS

Номер: US20180000647A1
Автор: Fu Hong, Hill James E., Malek Tabrizi Alireza
Принадлежит:

Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incisions to form a top lenticular incision, a bottom lenticular incision of a lens in the subject's eye, an added shape between the top and bottom incisions where the added shape has no corrective power and a transition ring bisecting both the top and bottom lenticular incisions. 1. A method for creating lenticular incisions to correct low myopic/hyperopic patients using an ophthalmic surgical laser system , the method comprising:generating a pulsed femtosecond laser beam;delivering the pulsed femtosecond laser beam into a stroma of a cornea;deflecting, by an XY-scan device, the pulsed laser beam;modifying, by a Z-scan device, a depth of a focus of the pulsed laser beam; and a top lenticular incision in the stroma of the cornea, having a circumferential periphery;', 'a bottom lenticular incision in the stroma of the cornea, symmetric to the top lenticular incision, having a circumferential periphery;', 'a shape with no correction power to space the top lenticular incision and the bottom lenticular incision; and', 'a transition ring or side cut incision intersecting the circumferential periphery of the top lenticular incision and the circumferential periphery of the bottom lenticular incision., 'controlling, by a controller, the XY-scan device and the Z-scan device to form an incised lenticule in the cornea, by incising,'}2. The method of wherein the shape with no correction power is determined based on the amount of correction of hyperopia and/or myopia needed.3. The method of wherein the incised lenticule is at least 40 μm thick at its center.4. The method of wherein low hyperopic/myopic patients are 0.5 diopters to 3.0 diopters.5. The method of wherein the transition ring incision has a top edge and a bottom edge claim 1 , and the top edge and the bottom edge have the same circumference.6. The method of wherein the transition ring has a ...

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Номер записи: 36
05-01-2017 дата публикации

CAPSULAR MEMBRANE IMPLANTS TO INCREASE ACCOMMODATIVE AMPLITUDE

Номер: US20170000601A1
Автор: Basinger Brooke C., Bor Zsolt, Brady Daniel G., Cali Douglas S., Geraghty Edward P., Reisin Carina R.
Принадлежит:

A support is coupled to the lens capsule to increase accommodation. The support may be adjustable, such that patient refraction and accommodation can be adjusted following surgery. The support may comprise rigidity sufficient to decrease radial movement of the intermediate portion of the lens capsule. The support can be placed on the intermediate portion to decrease radial movement of the intermediate portion of the lens capsule and increase radial stretching of an outer portion of the lens capsule extending between the zonules and the intermediate portion coupled to the support, such that the amount of accommodation of the eye is increased. The support may comprise a biocompatible material capable of stable coupling to the lens capsule following implantation, such that the far vision refraction and accommodation of the eye can be stable following surgery. 1. A method of treating an eye , the eye having a lens and a capsule , the method comprising:placing a support on an intermediate portion of the capsule to decrease radial movement of the intermediate portion and increase an amount of accommodation of the eye.2. The method of claim 1 , wherein a peripheral portion of the lens capsule is coupled to the intermediate portion of the lens capsule and wherein radial movement of the peripheral portion is increased when the support is coupled to the intermediate portion.3. The method of claim 1 , wherein a central portion of the lens capsule is coupled to the peripheral portion and wherein an anterior movement of the central portion is increased when the intermediate portion is coupled to the support.4. The method of claim 1 , wherein the decreased radial movement comprises one or more of a stretching claim 1 , a bending claim 1 , a flexing claim 1 , a translation or a rotation of the intermediate portion.5. The method of claim 1 , wherein the eye has a first amount of accommodation prior to placement of the support on the eye and a second amount of accommodation when the ...

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Номер записи: 37
05-01-2017 дата публикации

SUB-NANOSECOND LASER SURGERY SYSTEM UTILIZING MULTIPLE PULSED LASER BEAMS

Номер: US20170000647A1
Автор: ANDERSEN Daniel J., Gooding Phillip H., Schuele Georg, Vankov Alexander
Принадлежит:

A system for laser ophthalmic surgery includes: a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam. The first treatment laser beam has a pulse energy of 10 to 500 μJ. The second pulsed laser beam has a second pulse energy of about 0.1 to 10 μJ, lower than the first treatment laser beam. An optical system focuses the first treatment laser beam to a first focal spot and directs the first focal spot in a first treatment pattern into a first intraocular target. The optical system also focuses the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into a second intraocular target. The first intraocular target and second intraocular target are different. 1. A system for laser ophthalmic surgery on an eye of a patient , comprising:a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam, each treatment laser beam comprising a plurality of laser pulses, the first treatment laser beam having a pulse energy of about 10 to 500 μJ and the second pulsed laser beam having a second pulse energy of about 0.1 to 10 μJ and lower than the first treatment laser beam; andan optical system operatively coupled to the laser source by the controller and configured to focus the first treatment laser beam to a first focal spot and direct the first focal spot in a first treatment pattern into one or more intraocular targets, including a first intraocular target,the optical system being further configured to focus the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into the one or more intraocular targets, including a second intraocular target,wherein the first intraocular target is different than the second intraocular target.2. The system of ...

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Номер записи: 38
01-01-2015 дата публикации

Method and apparatus for treating an ocular disorder

Номер: US20150005623A1
Автор: David G. Godfrey, Davinder S. Grover, Ronald L. Fellman
Принадлежит: INNOVATIVE GLAUCOMA SOLUTIONS LLC

Embodiments of the claimed invention are directed to the treatment of glaucoma (or conditions of elevated intraocular pressure) using a novel ab interno trabeculotomy procedure that uses a flexible device. At least one advantage of the present method is that it does not require a conjunctival or scleral incision, which in turn improves patient recovery time and healing.

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Номер записи: 39
01-01-2015 дата публикации

Ophthalmological Laser Treatment Device

Номер: US20150005752A1
Автор: Bischoff Mark, Stobrawa Gregor
Принадлежит:

An evaluating unit which is adapted to determine a degree of an instantaneous overlap between an optical zone of the eye and the structure, or at least a part of the structure effecting refractive correction, based on a recorded image. By determining the degree of overlap between the instantaneous optical zone and the structure to be introduced, it is possible to control the superposition of the optical zone with the tissue volume which is specifically altered by means of the laser cutting and, accordingly, to enable a maximum coverage. 1. An ophthalmological laser treatment device comprising:a femtosecond laser configured to introduce energy into a portion of an eye of a patient according to a predetermined surgical structure;a light source configured to illuminate at least the portion of the eye;a detection device configured to record an image of at least the portion of the eye;an evaluating unit which is configured to determine a degree of an instantaneous overlap between an optical zone of the eye and the predetermined surgical structure or at least a part of the predetermined surgical structure effecting refractive correction based on a recorded image; anda contact element for mechanically fixating the eye.2. The ophthalmological treatment device according to ;wherein the evaluating unit is configured to determine an area of a pupil based on the recorded image and an area of the predetermined surgical structure, or at least of the part of the predetermined surgical structure effecting refractive correction, and an intersection between the two areas.3. The ophthalmological treatment device according to ;wherein the evaluating unit is configured to identify and locate a characteristic of the eye in the recorded image and to determine a relative offset between a point of the characteristic and a point of the predetermined surgical structure.4. The ophthalmological treatment device according to ;wherein the evaluating unit displays the recorded image visually in ...

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Номер записи: 40
20-01-2022 дата публикации

Calibration process for femtosecond laser intraocular lens modification system using video and oct targeting

Номер: US20220015949A1
Автор: Alexander Vankov, David A. Dewey, Georg Schuele, Jenny Wang, Phillip Gooding, Richard Hofer
Принадлежит: AMO DEVELOPMENT LLC

The XYZ beam position of an ophthalmic laser system is calibrated by measuring a fluorescent signal induced by the focused laser beam in a thin glass coverslip via multiphoton absorption. A video camera measures the XY position and intensity of the fluorescent signal as the focused laser beam strikes the coverslip. The Z position of the focus is determined by scanning the targeted z position and identifying the Z scanner position of peak fluorescence. An OCT system measures the real space Z location of the coverslip, which is correlated with the Z scanner position. Other laser system parameters are assessed by repeatedly scanning a lower energy laser beam in a piece of IOL material, and observing damage (scattering voids) formation in the IOL material. Based on the rate of damage formation, laser system parameters such as beam quality, numerical aperture, pulse energy, and pulse duration, etc. can be assessed.

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Номер записи: 41
12-01-2017 дата публикации

Ophthalmological apparatus for the breakdown of eye tissue

Номер: US20170007448A1
Автор: Christian Rathjen
Принадлежит: SIE Surgical Instrument Engineering AG

An ophthalmological apparatus includes a handle for manually holding and applying the ophthalmological apparatus, fastening abilities for fixing the ophthalmological apparatus at an eye, a light source, and a light projector for the focused projection of light pulses for punctiform tissue breakdown at a focal point in the interior of the eye tissue. The ophthalmological apparatus also includes a movement driver for moving the light projector. The movement of the light projector and therefore that of the focal point with the assistance of the movement driver permits a dimensioning of the optical projection system of the light projector which is substantially smaller than in the case of an ophthalmological apparatus where the focal point is moved exclusively by an optical projection system.

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Номер записи: 42
12-01-2017 дата публикации

LASER ASSISTED CATARACT SURGERY

Номер: US20170007453A1
Автор: Mordaunt David H.
Принадлежит:

Laser assisted cataract surgery methods and devices utilize one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may be applied to the anterior lens capsule to facilitate laser thermal separation of tissue along a treatment beam path on the lens capsule. Relative or absolute reflectance from the eye, and optionally from a surgical contact lens, may be measured to confirm and optionally quantify the presence of the light absorbing agent, before the treatment beam is applied. Such measurements may be used to determine that sufficient light absorbing agent is present in the lens capsule so that transmission of the treatment beam through the capsule will be below a predetermined threshold deemed safe for the retina and other interior portions of the eye, and may also be used to determine that sufficient light absorbing agent is present to result in complete laser thermal separation of the anterior capsule along the treatment beam path. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the capsulorrhexis procedure. In addition or alternatively, virtual visualization patterns may presented on a display integrated with a laser assisted cataract surgery device to aid in the procedure. The visual axis of the eye may be determined, during surgery for example, with a laser beam on which the patient is fixated. The orientation of a toric IOL may be assessed during or after placement by observing the reflection from the back of the eye of a laser beam on which the patient is fixated. The devices disclosed herein may be attached to or integrated with microscopes. 1. A device for creating an opening in the anterior lens capsule of the eye , the device comprising:a visible light laser beam blinking at a frequency perceptible to a human patient, directed into the eye, and establishing the visual ...

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Номер записи: 43
14-01-2016 дата публикации

APPARATUS AND METHOD FOR CREATING INCISIONS IN A HUMAN CORNEA

Номер: US20160008173A1
Автор: Donitzky Christof, Krause Johannes
Принадлежит:

An apparatus for creating incisions in a human cornea comprises: a source of pulsed laser radiation; a scanner device for scanning the laser radiation; and a control computer for controlling the scanner device based on a control program, the control program containing instructions that, when executed by the computer, bring about the creation in the cornea of: a flap cut defining a corneal flap that is connected to surrounding corneal tissue through a hinge; and one or more auxiliary cuts in connection with the flap cut for removing gas generated during creation of the flap cut, the one or more auxiliary cuts defining a first channel extending from the flap cut to an anterior surface of the cornea and a reservoir located at least partially deeper within the cornea than the flap cut. 1. An apparatus for creating incisions in a human cornea , the apparatus comprising:a source of pulsed laser radiation;a scanner device for scanning the laser radiation; a flap cut defining a corneal flap that is connected to surrounding corneal tissue through a hinge; and', 'one or more auxiliary cuts in connection with the flap cut for removing gas generated during creation of the flap cut, the one or more auxiliary cuts defining a first channel extending from the flap cut to an anterior surface of the cornea and a reservoir located at least partially deeper within the cornea than the flap cut., 'a control computer for controlling the scanner device based on a control program, the control program containing instructions that, when executed by the computer, bring about the creation in the cornea of2. The apparatus of claim 1 , wherein the reservoir is connected with the first channel.3. The apparatus of claim 1 , wherein locations of connection of the reservoir and the first channel with the flap cut are at least partially overlapping.4. The apparatus of claim 1 , wherein the reservoir and the first channel are each connected with the flap cut in a hinge area of the flap.5. The apparatus ...

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Номер записи: 44
11-01-2018 дата публикации

Laser patterning apparatus for three-dimensional object

Номер: US20180008370A1
Автор: Byoung Chan CHOI, Doo Baeck An
Принадлежит: Advanced Technology Inc

A laser patterning apparatus for a three-dimensional object includes a laser generator, a beam expander configured to adjust a size of a laser beam generated by the laser generator, a dynamic focusing module configured to adjust a z-axis focus position of the laser beam passing through the beam expander, a scan head configured to adjust x- and y-axis focus position of the laser beam passing through the beam expander, a shape recognizer configured to recognize a shape of a three-dimensional object, and a controller configured to extract x-, y-, and z-axis data of the three-dimensional object and to control the scan head and the dynamic focusing module, in order to pattern the three-dimensional object with the laser beam.

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Номер записи: 45
11-01-2018 дата публикации

LENTICULAR LASER INCISION USING WAVEFRONT GUIDED MAPS

Номер: US20180008461A1
Автор: Chernyak Dimitri, Dai Guangming G., Fu Hong, Malek Tabrizi Alireza, Neal Daniel R., Raymond Thomas D.
Принадлежит:

Embodiments generally relate to systems and methods for lenticular laser incisions based on wavefront maps. In an embodiment, a method comprises obtaining a wavefront map of a free eye using wavefront aberrometry to measure a refractive error, obtaining an iris image for the free eye using wavefront aberrometry, determining a free eye cutting profile to cut the cornea based on the wavefront measurement, determining a first translation of the free eye cutting profile based on estimated perturbation of the eye with a docking patient interface, docking the eye to a patient interface of an ultrashort pulsed laser system, obtaining an iris image for the docked eye, determining a second translation of the cutting profile for the docked eye from the free eye, using comparisons between the two iris images, and incising a bottom surface incision in the cornea based on the two translated cutting profiles. 1. A method of performing ophthalmic surgery , comprising:obtaining a wavefront map of a free eye using a wavefront aberrometer to measure a refractive error;obtaining an iris image of the free eye using the wavefront aberrometer;determining with a computer, comprising a processor and memory in communication with the wavefront aberrometer, a free eye cutting profile to cut in a cornea of the eye, based on the wavefront aberrometer measurement;determining with the computer, a first translation of the free eye cutting profile based on an estimated perturbation of the eye by a docking patient interface;docking the eye to the patient interface of an ultrashort pulsed laser system;obtaining an iris image of the docked eye by the ultrashort pulsed laser system;determining a second translation of the cutting profile for the docked eye from the free eye, by the computer, using the iris image for the docked eye compared to the iris image of the free eye; andincising, by the ultrashort pulsed laser system, a bottom surface incision in the cornea based on the first translation of the ...

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Номер записи: 46
11-01-2018 дата публикации

LASER SCANNER APPARATUS AND METHOD

Номер: US20180008466A1
Автор: Anderegg Jesse Peter
Принадлежит:

An apparatus for ophthalmic procedures contains a source of aiming and treatment laser beams, folded mirrors and lens arrays to cause the formation of a static pupil on a delivery mirror for observation and treatment by an operator of the apparatus. 114-. (canceled)15. A device comprising:a treatment laser source;one or more scanning mirrors downstream in an optical path of a laser beam from the treatment laser source, the scanning mirrors producing an astigmatic pupil from the laser beam of the treatment laser source;one or more lens systems downstream from and in the optical path of a laser beam from the scanning mirrors;the one or more lens systems adjusting the light beam from the scanning mirrors such that a light beam from the one or more lens systems converges as a pupil on a delivery mirror;the one or more lens systems converting the astigmatic pupil to a non-astigmatic pupil;wherein the one or more lens systems form a static pupil on the delivery mirror which is independent of any movement, position or pattern defined by the one or more scanning mirrors.16. The device of claim 15 , further comprising:a binocular observation device having a central optical axis and two longitudinal axes operatively associated with the central axis;the delivery mirror being located between the longitudinal axes of the binocular observation device, and wherein the delivery mirror deflects the laser beam from the treatment laser source to be coincident with the central optical axis of the binocular observation device.17. The device according to wherein the laser beam from the treatment laser source is deflected onto an area of target tissue to be treated in a direction orthogonal to its direction upstream of the mirror.18. The device according to wherein the size of the area of treatment is independent of the size of the delivery mirror.19. The device according to claim 16 , wherein the device is a stand-alone scanner which is linked to a binocular observation device for ...

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Номер записи: 47
27-01-2022 дата публикации

METHODS OF TRANSVERSE PLACEMENT IN ELT

Номер: US20220023098A1
Автор: Enders Markus, Junger Johannes
Принадлежит:

Glaucoma patients suffer from increased intraocular pressure due to blocked fluid flow from the anterior chamber of the eye. Methods of the invention include inserting a probe into an eye of a subject having glaucoma, adjusting placement of the probe to a position transverse to Schlemm's canal in the eye, and applying a plurality of shots from an excimer laser source while the probe is in the transverse position, thereby treating glaucoma by creating a plurality of perforations in Schlemm's canal and/or the trabecular meshwork. By providing a laser probe at a position transverse to Schlemm's canal, energy from the laser is delivered to a greater amount of surface area than if the laser was arranged in a parallel or perpendicular position to Schlemm's canal, resulting in optimal formation of perforations. The perforations allow for drainage of fluid and increased outflow of aqueous humor in the eye. 115-. (canceled)16. An apparatus for delivering laser energy to a surface of a trabecular meshwork of an eye to treat glaucoma comprising:an excimer laser source;a probe configured to connect to the excimer laser source; and the probe is configured to be inserted into an eye of a subject having glaucoma;', "the delivery tip of the probe is shaped to be placed at a position transverse to Schlemm's canal in the eye;", "the probe is further configured to deliver a plurality of shots of energy from an excimer laser source to create a plurality of perforations having transverse placement in the trabecular meshwork relative to the Schlemm's canal of the eye, wherein the plurality of perforations are created in the trabecular meshwork in order to treat the glaucoma."], 'a delivery tip connected to the probe, wherein17. The apparatus of claim 16 , wherein a light source aids in placement of the delivery tip of the probe.18. The apparatus of claim 17 , wherein the light source is a Gonio lens claim 17 , endoscope claim 17 , or other illumination source.19. The apparatus of claim ...

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Номер записи: 48
27-01-2022 дата публикации

Device for Ophthalmic Surgery and Method of Use Therefor

Номер: US20220023099A1
Автор: John A. McCall, JR.
Принадлежит: Individual

A lens device for use in Selective Laser Trabeculoplasty (SLT) procedures is provided. The lens device includes four internal reflectors, each having a reflector surface configured to direct a laser beam pulse toward the trabecular meshwork region of a patient's eye. Each of the four internal reflectors is arranged to correspond to a particular quadrant of the patient's eye to enable the entire 360-degrees of the trabecular meshwork to be treated with laser pulses without rotation of the lens device. A method for performing an SLT procedure using the lens device is also provided. The method includes placing the lens device on the patient's eye, aligning the internal reflectors with the quadrants of the patient's eye, and directing laser pulses through each internal reflector until the trabecular meshwork in each quadrant of the patient's eye has been treated.

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Номер записи: 49
10-01-2019 дата публикации

OPHTHALMIC TREATMENT DEVICE, SYSTEM, AND METHOD OF USE

Номер: US20190008678A1
Автор: Daly Kevin E., Feldman Sandy T., Hartman (deceased) Raymond A., Rubinfeld Roy S.
Принадлежит:

Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye). The at least one treatment light promotes corneal and/or scleral collagen cross-linking. 1. An ophthalmic treatment system , comprising:a light source device comprising at least one light source;at least one optical treatment head operatively coupled to the light source device, and configured to provide at least one treatment light;at least one processor associated with the light source device and programmed to control operation of the light source device to provide a discontinuous treatment light projection onto a patient's eye for a selected treatment time comprising successive treatment light exposure periods of a first light intensity level separated by non-treatment periods at a second light intensity level lower than the first light intensity level; andwherein the at least one optical treatment head projects the treatment light at least two inches to the patient's eye such that a position of the at least one optical treatment head relative to the patient's eye allows physician visualization and accessibility to the patient's eye during treatment.2. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the treatment light at least three inches to the patient's eye.3. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the ...

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Номер записи: 50
10-01-2019 дата публикации

OPHTHALMIC TREATMENT DEVICE, SYSTEM, AND METHOD OF USE

Номер: US20190008679A1
Автор: Daly Kevin E., Feldman Sandy T., Hartman (deceased) Raymond A., Rubinfeld Roy S.
Принадлежит:

Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye). The at least one treatment light promotes corneal and/or scleral collagen cross-linking. 1. An ophthalmic treatment system , comprising:a light source device comprising at least one light source;at least one optical treatment head operatively coupled to the light source device, and configured to provide at least one treatment light;at least one processor associated with the light source device and programmed to control operation of the light source device to provide a discontinuous treatment light projection onto a patient's eye for a selected treatment time comprising successive treatment light exposure periods of a first light intensity level separated by non-treatment periods at a second light intensity level lower than the first light intensity level; andwherein each treatment light exposure period and non-treatment period of the discontinuous treatment light projection is in the range from 5 seconds to 25 seconds.2. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the treatment light at least two inches to the patient's eye.3. The ophthalmic treatment system of claim 1 , wherein the at least one optical treatment head projects the treatment light between three to six inches to the patient's eye.4. The ophthalmic treatment system of claim 1 , wherein the treatment light ...

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Номер записи: 51
11-01-2018 дата публикации

CONFORMABLE THERAPEUTIC SHIELD FOR VISION AND PAIN

Номер: US20180011341A1
Автор: Alster Yair, Barragan Enrique, Carson Dean, Clarke Matt, de Juan, JR. Eugene, Levy Brian, MacFarlane K. Angela, Reich Cary J., Rimer Doug, Sutton Douglas, Tuan Ashley
Принадлежит:

A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. 1. A covering to treat an eye of a patient , wherein ,the eye comprises a cornea, an ablated stroma, and an epithelium, wherein the epithelium comprises an inner portion comprising irregularities characterized by an irregularity profile and an outer portion;the covering comprises a conformable inner portion comprising an upper surface profile;the covering comprises an outer portion configured to adhere to the outer portion of the epithelium; andthe upper surface profile corresponds to a profile of the ablated stroma and is configured to smooth the irregularities when the outer portion of the covering adheres to the outer portion of the epithelium.2. The covering of claim 1 , wherein claim 1 ,the irregularity profile comprises spatial frequencies;the upper surface profile comprises spatial frequencies; andthe upper surface profile spatial frequencies are lower than the spatial frequencies of the irregularity profile.3. The covering of claim 1 , wherein the conformable inner portion comprises a stretchable material configured to stretch across the irregularities of the epithelium and to smooth the irregularities transferred from the irregularity ...

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Номер записи: 52
12-01-2017 дата публикации

METHODS AND SYSTEMS FOR LASER SCAN LOCATION VERIFICATION AND LASER SURGICAL SYSTEMS WITH LASER SCAN LOCATION VERIFICATION

Номер: US20170011501A1
Автор: Gonzalez Javier G., Hart John S.
Принадлежит:

A method of verifying a laser scan at a predetermined location within an object includes imaging at least a portion of the object, the resulting image comprising the predetermined location; identifying the predetermined location in the image, thereby establishing an expected scan location of the laser scan in the image; performing a laser scan on the object by scanning a focal point of the laser beam in a scanned area; detecting a luminescence from the scanned area and identifying an actual scanned location within the image based on the detected luminescence; and determining whether the difference between the actual scanned location and the expected scan location is within a threshold value. 1. A method of verifying the placement a laser scan at a predetermined location within an object , comprising:imaging at least a portion of the object, the resulting image comprising the predetermined location;identifying the predetermined location in the image, thereby establishing an expected scan location of the laser scan in the image;performing the laser scan on the object by scanning a focal point of a laser beam in a scanned area;detecting a luminescence from the scanned area and identifying an actual scanned location within the image based on the detected luminescence; andverifying whether the laser scan was at the predetermined location based on a difference between the actual scanned location and expected scan location.2. The method of claim 1 , wherein the object is a human eye.3. The method of claim 1 , wherein the object is a calibration apparatus.4. The method of claim 1 , wherein the laser beam is a pulsed laser beam having a wavelength of 320 nm to 370 nm.5. The method of claim 1 , wherein the luminescence has a wavelength of 400 nm or more.6. The method of claim 1 , wherein the image comprises an array of pixels.7. The method of claim 6 , wherein the expected location comprises one or more pixels selected from amongst the array of pixels.8. The method of claim 6 ...

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Номер записи: 53
03-02-2022 дата публикации

LASER THERAPY FOR TREATMENT AND PREVENTION OF EYE DISEASES

Номер: US20220031503A1
Автор: Ballard Michael K., Binder Perry, Dorin Giorgio, Eddington William, HEREKAR Satish, Samples John Randall
Принадлежит: ALeyeGN Technologies LLC

An ab externo automated laser treatment system for treating an eye in a subject, includes a non-contact laser source configured to generate a laser beam having at least one wavelength to treat the eye by directing the laser beam from a location spaced from the eye, wherein the at least one wavelength is a near-infrared wavelength in the range of about 0.5-2.2 μm, a laser scanner optically coupled to the non-contact laser source to receive the laser beam from the non-contact laser source and to scan the laser beam relative to the eye, and a processor, and memory including stored computer-readable instructions that, responsive to execution by the processor, cause the laser treatment system to direct the laser beam to a plurality of trans-scleral treatment locations to be irradiated in a predetermined treatment pattern on an external surface of the eye, wherein the trans-scleral treatment locations are 0-4 mm posterior to the corneolimbal junction, and wherein the laser beam is repetitively directed to the same irradiated trans-scleral treatment locations on the surface of the eye, and the trans-scleral treatment locations are irradiated at intervals sufficient to induce protective thermal preconditioning and therapeutic bio-stimulation of one or more of the trabecular meshwork and/or ciliary body without photocoagulation of the tissue of the eye. Trans-pupillary systems, patient interfaces, and methods are also disclosed. 1. An ab externo automated laser treatment system for treating an eye in a subject , comprising:a non-contact laser source configured to generate a laser beam having at least one wavelength to treat the eye by directing the laser beam from a location spaced from the eye, wherein the at least one wavelength is a near-infrared wavelength in the range of about 0.5-2.2 μm;a laser scanner optically coupled to the non-contact laser source to receive the laser beam from the non-contact laser source and to scan the laser beam relative to the eye; anda ...

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Номер записи: 54
03-02-2022 дата публикации

Systems and Methods for Performing an Intraocular Procedure for Treating an Eye Condition

Номер: US20220031513A1
Автор: Enders Markus, Junger Johannes
Принадлежит:

The invention provides an excimer laser system including a means for calibrating laser output to compensate for increased variation in laser optical fibers. 114-. (canceled)15. A method for performing an intraocular procedure for treating an eye condition , said method comprising: the data is indicative of at least a diameter of a fiber optic core of the one of the plurality of excimer laser probes,', 'the excimer laser source is configured to generate laser energy to be provided to each of the plurality of excimer laser probes, and', 'the plurality of excimer laser probes are single use and disposable, such that the plurality of excimer laser probes are each coupleable, one at a time, to said excimer laser source; and, 'upon each instance of connecting one of a plurality of excimer laser probes to an excimer laser source, automatically receiving, by a processor in communication with the excimer laser source, data from the one of the plurality of excimer laser probes coupled to the excimer laser source, whereinautomatically fine tuning and adjusting, by the processor, laser energy output from the excimer laser source to the one of the plurality of excimer laser probes based on the diameter of the fiber optic core such that the laser energy output from the one of the plurality of excimer laser probes is maintained at a desired level.16. The method of claim 15 , further comprising analyzing claim 15 , by the processor. the data by correlating the data with calibration data stored in a database.17. The method of claim 16 , wherein the calibration data is associated with the laser energy output from the excimer laser source.18. The method of claim 16 , wherein the calibration data is stored in a local database.19. The method of claim 16 , wherein the calibration data is stored in a remote database.20. The method of claim 16 , further comprising determining claim 16 , by the processor claim 16 , the laser energy output based on the correlation of the data with the ...

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Номер записи: 55
19-01-2017 дата публикации

DEVICE AND METHOD FOR LASER ASSISTED DEEP SCLERECTOMY

Номер: US20170014271A1
Автор: Degani Joshua, Eyal Ami
Принадлежит: I Optima Ltd.

An ophthalmic laser ablation system is described with various optional features, some especially suitable for non-penetrating filtration on an eye. In one example, focusing of an ablation laser uses a movable lens coupled to a pair of converging light sources, which converge at the focal distance of the lens. In another example, laser ablation settings are selected for optimal ablation and minimal amount of thermal damage of a layer of percolating scleral tissue. 1. A laser ablation control system , comprising:(a) a frame adapted for attachment to an ophthalmic microscope and including a portion which is adjacent to a field of view of said microscope;(b) a beam combiner in the field of view of said microscope;(c) a beam scanner adjacent said portion and with an output aimed at said beam combiner;(d) a converging lens between said scanner and said beam combiner; and(e) at least one patterned light source fixedly coupled to said lens and aimed at said beam combiner, which light source generates a pattern having a pre-determined form at a focal location of said output.2. A system according to claim 1 , wherein said at least one patterned light source comprises at least two point sources claim 1 , generating a converging pair of rays which converge at said focal location.3. A system according to claim 2 , wherein the at least two point sources are each mounted within 5 cm from a center of said lens and on opposite sides thereof.4. A system according to or claim 2 , wherein the at least two point sources are each mounted within 3 cm from a center of said lens.5. A system according to any of - claim 2 , wherein said beam combiner comprising a path folding mirror configured to be transparent to most wavelengths of visible light and configured to reflect both ablation wavelengths and said patterned light.6. A system according to any of - claim 2 , comprising a focus adjusting element adapted to move said lens together with said patterned light source to change a distance of ...

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Номер записи: 56
17-01-2019 дата публикации

Apparatus for Working on Eye Tissue by Means of a Pulsed Laser Beam

Номер: US20190015250A1
Автор: Rathjen Christian
Принадлежит:

For the purposes of working on eye tissue, an ophthalmological apparatus comprises a laser source that is configured to produce a pulsed laser beam, a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue, and a scanner system for deflecting the pulsed laser beam onto work target points in the eye tissue. The scanner system is configured to guide the pulsed laser beam onto work target points along a scan line that extends across a work line at an alignment angle and to tilt the scan line depending on the work target point on the work line in such a way that the scan line extends substantially along an outer face of a lenticule to be cut in the eye tissue. 1. Ophthalmological apparatus for working on eye tissue , comprising a laser source that is configured to produce a pulsed laser beam; a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue; a scanner system , comprising a first scanner module and a second scanner module , for deflecting the pulsed laser beam onto work target points in the eye tissue; and a circuit for controlling the ophthalmological apparatus; whereinthe circuit is configured to control the second scanner module in such a way that the second scanner module guides the pulsed laser beam in a feed direction onto work target points along a work line that extends along an outer face of a lenticule to be cut in the eye tissue, transversely to meridians of the lenticule;the first scanner module is configured to guide the pulsed laser beam onto work target points along a scan line that extends across the work line at an alignment angle in a horizontal work plane, with a substantially higher scanning speed in comparison with the scanning speed of the second scanner module in the feed direction; andthe ophthalmological apparatus comprises a z-modulator that is configured to tilt the scan line out of the work plane depending on a specific work target point of the second scanner ...

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Номер записи: 57
17-01-2019 дата публикации

APPARATUS FOR WORKING ON EYE TISSUE BY MEANS OF A PULSED LASER BEAM

Номер: US20190015251A1
Автор: Rathjen Christian
Принадлежит:

For the purposes of working on eye tissue, an ophthalmological apparatus comprises a laser source that is configured to produce a pulsed laser beam, a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue, and a scanner system for deflecting the pulsed laser beam onto work target points in the eye tissue. A circuit controls the scanner system in such a way that the scanner system guides the pulsed laser beam into work trajectories that extend next to one another, in order, initially, to produce cut trajectories, separated by remaining tissue bridges, of a tissue cut to be undertaken in an area and in order, thereafter, to guide the pulsed laser beam in the remaining tissue bridges between the cut trajectories in order to complete the tissue cut. 1. Ophthalmological apparatus for working on eye tissue , comprising a laser source that is configured to produce a pulsed laser beam; a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue; a scanner system that is configured to guide the pulsed laser beam onto work target points in the eye tissue; and a circuit that is configured to control the scanner system in such a way that the scanner system guides the pulsed laser beam onto work target points in an area to be cut in a cornea , in work trajectories that extend next to one another , in order , initially , to produce cut trajectories , separated by remaining tissue bridges , of a tissue cut to be undertaken in the area and in order , thereafter , to guide the pulsed laser beam onto work target points in the remaining tissue bridges between the cut trajectories in the area in order to complete the tissue cut , wherein the ophthalmological apparatus comprises a measurement system that is configured to optically capture structures in the eye tissue; and the circuit is configured to control the measurement system in such a way that the measurement system captures the produced cut trajectories and ...

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Номер записи: 58
17-01-2019 дата публикации

APPARATUS FOR WORKING ON EYE TISSUE BY MEANS OF A PULSED LASER BEAM

Номер: US20190015253A1
Автор: Rathjen Christian
Принадлежит:

For the purposes of working on eye tissue, an ophthalmological apparatus comprises a laser source that is configured to produce a pulsed laser beam, a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue, a scanner system for deflecting the pulsed laser beam onto work target points in the eye tissue, and a measurement system for optically capturing structures in the eye tissue. A circuit controls the measurement system in such a way that the latter captures a cut first outer face of a lenticule to be cut. The circuit controls the scanner system in such a way that the latter guides the pulsed laser beam onto work target points on a second outer face, positioned in relation to the captured first outer face, of the lenticule to be cut, in order to cut the second outer face of the lenticule. 1. Ophthalmological apparatus for working on eye tissue , comprising a laser source that is configured to produce a pulsed laser beam; a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue; a scanner system that is configured to guide the pulsed laser beam onto work target points in the eye tissue; a measurement system that is configured to optically capture structures in the eye tissue; and a circuit that is configured to control the scanner system in such a way that the scanner system guides the pulsed laser beam onto work target points on a first outer face of a lenticule to be cut in the eye tissue in order to produce a first tissue cut for cutting the lenticule;where the circuit is further configured to control the measurement system in such a way that the measurement system captures the first outer face of the lenticule that is produced by the first tissue cut and to control the scanner system in such a way that the scanner system guides the pulsed laser beam onto work target points on a second outer face, positioned in relation to the captured first outer face of the lenticule to be cut in order to ...

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Номер записи: 59
21-01-2021 дата публикации

OPHTHALMIC LASER DELIVERY APPARATUS USING MEMS MICROMIRROR ARRAYS FOR SCANNING AND FOCUSING LASER BEAM

Номер: US20210015667A1
Автор: Gonzalez Javier G.
Принадлежит:

In a laser delivery system for an ophthalmic laser surgery system, a laser beam scanner employs a single or two MEMS micromirror arrays. Each micromirror in the array is capable of being independently actuated to rotate to desired angles. In one embodiment, one or two micromirror arrays are controlled to scan a laser beam in two directions. In another embodiment, a micromirror array is controlled to both correct optical aberrations in the laser beam and scan the laser beam in two directions. In yet another embodiment, a micromirror array is controlled to cause the laser beam to be focused to multiple focal spots simultaneously and to scan the multiple focal spot simultaneously. The ophthalmic laser surgery system also includes an ultrashort pulse laser, a laser energy control module, focusing optics and other optics, and a controller for controlling the laser beam scanner and other components of the system. 17-. (canceled)8. An ophthalmic laser delivery method for delivering a pulsed laser beam generated by a laser to a patient's eye , comprising:directing the pulsed laser beam from the laser to a laser beam scanner, the laser beam scanner including at least one micromirror array, the micromirror array including a plurality of micromirrors forming a two-dimensional array, the plurality of micromirrors capable of being individually controlled to rotate to different angles;using a controller coupled to the laser beam scanner, controlling a rotation of each of the plurality of micromirrors of the at least one micromirror array, to reflect the pulsed laser beam to generate one or more output laser beams and to scan the output laser beams in two orthogonal directions according to a predefined scan pattern; anddirecting the output laser beams from the laser beam scanner to the patient's eye to form one or more focal spots that are scanned within an arear of the eye.9. The ophthalmic laser delivery method of claim 8 , wherein the laser beam scanner includes two micromirror ...

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Номер записи: 60
21-01-2021 дата публикации

SYSTEMS AND METHODS FOR HIGH SPEED MODULATION OF A RESONANT SCANNER IN OPHTHALMIC LASER APPLICATIONS

Номер: US20210015668A1
Автор: Fu Hong, Hill James E., Malek Tabrizi Alireza, Witowski Zenon
Принадлежит:

An ophthalmic surgical laser system includes: a laser that produces a pulsed laser beam having a pulse energy and pulse repetition rate; a high frequency fast scanner; an XY-scan device; a Z-scan device; and a controller. The controller controls the high frequency scanner to produce a scan line having a scan width; controls the XY-scan device and the Z-scan device to carry out of first sweep of the scan line in a first sweep direction and to carry out a second sweep of the scan line in a second sweep direction that is not parallel to the first sweep direction thereby defining an overlap region. At least one of the pulse energy, repetition rate, XY-scan speed, and the scan width is varied so as to accelerate the cutting speed and reduce the exposure of ophthalmic tissue in the overlap region to multiple exposures of laser pulses configured to modify ophthalmic tissue. 111-. (canceled)12. A method for creating a lenticular incision using an ophthalmic surgical laser system , the method comprising the steps of:generating, with a laser, a pulsed laser beam to a target in a subject's eye; the pulsed laser beam having a pulse energy and pulse repetition rate;generating a scan line, the scan line having a scan width;controlling, via a controller, an XY-scan device and a Z-scan device to conduct a first sweep of the fast scan line in a first sweep direction;controlling, via the controller, the XY-scan device and the Z-scan device to conduct a second sweep of the scan line in a second sweep direction that is not parallel to the first sweep direction, thereby defining an overlap region;wherein at least one of the pulse energy, the repetition rate, XY-scan speed, and the scan width are varied during at least one of the first sweep and second sweep so as to reduce the exposure of ophthalmic tissue in the overlap region to multiple exposures of laser pulses configured to modify ophthalmic tissue.13. The method of claim 12 , wherein the ophthalmic surgical laser system further ...

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Номер записи: 61
16-01-2020 дата публикации

SYSTEM AND METHOD FOR ANGLED OPTICAL ACCESS TO THE IRIDO-CORNEAL ANGLE OF THE EYE

Номер: US20200016000A1
Автор: Raksi Ferenc
Принадлежит:

A first optical subsystem includes a window with a refractive index nand an exit lens having a refractive index n. The exit lens is configured to couple to the window to define a first optical axis extending through the window and the exit lens. A second optical subsystem is configured to output a light beam. The light beam is directed to be incident at a convex surface of the exit lens along a second optical axis at an angle α that is offset from the first optical axis. The window is configured to detachably couple to the cornea of the eye such that the first optical axis is generally aligned with a direction of view of the eye. The respective refractive indices nand nare configured to direct the light beam incident at the convex surface of the exit lens through the cornea of the eye toward the irido-corneal angle. 1. An optical system for directing a light beam to an irido-corneal angle of an eye , the eye having a direction of view and a cornea with a refractive index n , the optical system comprising: [{'sub': 'w', 'a window formed of a material with a refractive index n, the window having a concave surface and a convex surface opposite the concave surface, and'}, {'sub': 'x', 'an exit lens formed of a material having a refractive index n, the exit lens having a concave surface and a convex surface opposite the concave surface, wherein the concave surface of the exit lens is configured to couple to the convex surface of the window to define a first optical axis extending through the window and the exit lens; and'}], 'a first optical subsystem comprisinga second optical subsystem configured to output a light beam, the light beam is directed to be incident at the convex surface of the exit lens along a second optical axis at an angle α that is offset from the first optical axis,', 'the concave surface of the window is configured to detachably couple to the cornea of the eye such that the first optical axis is generally aligned with the direction of view, and', {' ...

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Номер записи: 62
16-01-2020 дата публикации

INTEGRATED SURGICAL SYSTEM AND METHOD FOR TREATMENT IN THE IRIDO-CORNEAL ANGLE OF THE EYE

Номер: US20200016002A1
Автор: Raksi Ferenc
Принадлежит:

Intraocular pressure in an eye is reduced by delivering each of a high resolution optical coherence tomography (OCT) beam and a high resolution laser beam through the cornea, and the anterior chamber into the irido-corneal angle along an angled beam path. The OCT beam provides OCT imaging for diagnostic purposes and surgery planning and monitoring, while the laser beam is configured to modify tissue. A volume of ocular tissue within an outflow pathway in the irido-corneal angle is modified to reduce a pathway resistance present in one or more of the trabecular meshwork, the Schlemm's canal, and the one or more collector channels by applying the laser beam to ocular tissue defining the volume to thereby cause photo-disruptive interaction with the ocular tissue to reduce the pathway resistance or create a new outflow pathway. 1. A method of reducing intraocular pressure in an eye having a cornea , an anterior chamber , and an irido-corneal angle comprising an aqueous humor outflow pathway formed of a trabecular meshwork , a Schlemm's canal , and one or more collector channels branching from the Schlemm's canal , the method comprising:delivering each of an optical coherence tomography (OCT) beam and a laser beam through the cornea, and the anterior chamber into the irido-corneal angle; andmodifying a volume of ocular tissue within the outflow pathway to reduce a pathway resistance present in one or more of the trabecular meshwork, the Schlemm's canal, and the one or more collector channels by applying the laser beam to ocular tissue defining the volume to thereby cause photo-disruptive interaction with the ocular tissue to reduce the pathway resistance or create a new outflow pathway.2. The method of claim 1 , wherein delivering each of an OCT beam and a laser beam comprises directing each beam to a first optical subsystem comprising a window coupled to the cornea and an exit lens coupled to the window.3. The method of claim 2 , wherein:the eye comprises a direction of ...

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Номер записи: 63
28-01-2016 дата публикации

Systems and Methods for Laser Beam Direct Measurement and Error Budget

Номер: US20160022492A1
Автор: Berezhnyy Ihor, Calebotta Stephen, Dai Guangming, Fabrikant Anatoly, Logan Benjamin, Price Henry, Tang Anthony
Принадлежит:

Embodiments of the present invention generally describe systems, devices, and methods for directly measuring pulse profiles during pulse delivery. In some embodiment, the pulse profiles may be measured while the pulse is delivered to ablate a material. Embodiments, may calculate ablation spot parameters based on the pulse profiles and may refine one or more subsequent laser pulses based on deviations from the calculated ablation spot parameters from desired ablation spot parameters. In some embodiments, a fluence profiler is provided. The fluence profiler may measure a pulse profile of a laser pulse from a portion of the laser pulse. The fluence profiler may utilize a UV radiation energy sensor device and a camera-based imager. The measurements from the UV radiation energy sensor device and the camera-based imager may be combined and scaled to provide a measured pulse profile that corresponds to the delivered pulse. 1. A method comprising:generating a first laser pulse;delivering a portion of the first laser pulse to a beam profiler;delivering a remainder of the first laser pulse to a material;ablating the material at a treatment plane with the remainder of the first laser pulse to create an ablation spot;measuring a pulse profile of the first laser pulse with the beam profiler;calculating ablation parameters that correspond to the ablation spot based on the measured pulse profile;adjusting a delivery of a second laser pulse to the material based on the measured pulse profile of the first laser pulse.2. The method of claim 1 , wherein the material comprises a tissue of an eye claim 1 , and wherein the beam profiler comprises a beam splitter for directing a first part of the portion of the first laser pulse to a ultraviolet radiation energy sensor and a second part of the portion of the first laser pulse to a camera-based imager.3. The method of claim 2 , wherein the camera-based imager comprises a UV-to-visible converter plate claim 2 , an image sensor claim 2 , and ...

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Номер записи: 64
28-01-2016 дата публикации

Method of altering the refractive properties of an eye

Номер: US20160022493A1
Автор: Gholam A. Peyman
Принадлежит: Individual

The present invention relates to a method of altering the refractive properties of the eye, the method including applying a substance to a cornea of an eye, the substance configured to facilitate cross linking of the cornea, irradiating the cornea so as to activate cross linkers in the cornea, and altering the cornea so as to change the refractive properties of the eye.

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Номер записи: 65
26-01-2017 дата публикации

GLAUCOMA DRAINAGE SHUNTS AND METHODS OF USE

Номер: US20170020731A1
Автор: Baerveldt George
Принадлежит:

A method of treating glaucoma in an eye utilizing an implanted shunt having an elastomeric plate and a non-valved elastomeric drainage tube. The plate is positioned over a sclera of the eye with an outflow end of the elastomeric drainage tube open to an outer surface of the plate. An inflow end of the drainage tube tunnels through the sclera and cornea to the anterior chamber of the eye. The drainage tube collapses upon initial insertion within an incision in the sclera and cornea, or at a kink on the outside of the incision, but has sufficient resiliency to restore its patency over time. The effect is a flow restrictor that regulates outflow from the eye until a scar tissue bleb forms around the plate of the shunt. The plate desirably has a peripheral ridge and a large number of fenestrations, and a longer suturing tab extending from one side of the plate to enhance visibility and accessibility when suturing the shunt to the sclera. 112.-. (canceled)13. A glaucoma drainage device , comprising:a plate; andan elastomeric drainage tube having an open cross-section, an outflow end of the elastomeric drainage tube connected to a part of the plate and an inflow end extending away from the plate, the drainage tube having an open lumen and a tube wall with a hoop strength, wherein the inflow end of the drainage tube is configured to be inserted through an incision at or near the limbus of an eye and into the anterior chamber of the eye, wherein the drainage tube has an outside diameter of less than about 0.50 mm and a wall thickness of less than about 0.125 mm.14. The glaucoma drainage device of claim 13 , wherein the plate has a thickness of between about 0.25 to 3.0 mm.15. The glaucoma drainage device of claim 13 , wherein the plate has a concave inner surface and a convex outer surface and wherein the concave inner surface has a radius of curvature between about 12 mm and about 14 mm claim 13 , and the surface area of the plate is between about 100 mmand about 600 mm.16 ...

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Номер записи: 66
24-01-2019 дата публикации

PRODUCING CUT SURFACES IN A TRANSPARENT MATERIAL BY MEANS OF OPTICAL RADIATION

Номер: US20190021905A1
Автор: Bischoff Mark, Papastathopoulos Evangelos, Stobrawa Gregor
Принадлежит:

A method for producing a cut surface in a transparent material using optical radiation. A laser device separates the material using optical radiation and includes an optical unit focussing the radiation along an optical axis into an image field defining an image-field size. A focal position is adjusted transversely along the axis, producing a cut surface extending substantially parallel to the axis and, in projection along the axis, is a curve having a maximum extent. The focus is displaced by adjustment of the focal position along a trajectory curve lying in the cut surface. The cut surface has a maximum extent which is greater than the image-field size. The focal position is moved transverse to the axis along the curve. The image field is displaced transversely, and the focal position is adjusted in an oscillating fashion along the axis on the curve between an upper and lower axial focus position. 1. A treatment apparatus for producing a cut in a transparent material , the apparatus comprising:a laser device which is adapted to generate a cut within the transparent material using optical radiation, the laser devicea control device which is connected to the laser device and controls the laser device such that a focus adjustment device moves the position of the focus of the optical radiation in the material along a path, wherein the control device controls the laser device such that the cut has, in projection along an optical axis, a form of a curve,2. A method for producing control data for producing a cut in a transparent material , whereinthe control data are designed for a laser device comprising: 'a focus adjustment device for moving a position of the focus,', 'optics configured to focus the optical radiation along an optical axis into a focus situated in the material and which have in the material an image field in which the focus lies and which has an image field size, and'}wherein the control data are produced to comprise data for the focus adjustment device ...

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Номер записи: 67
24-01-2019 дата публикации

SYSTEM AND METHOD FOR LASER CORNEAL INCISIONS FOR KERATOPLASTY PROCEDURES

Номер: US20190021908A1
Автор: Scott David D.
Принадлежит:

A first image of the eye is generated when the cornea of the eye is exposed to a gas. The cornea is covered with an optic of a patient interface. A second image of the eye with the patient interface over the cornea is generated. In this second image, the patient interface distorts the second image of the eye. One or more of a position or an orientation of the eye is determined in response to the first image and the second image when the patient interface has been placed over the cornea. 1. A method of treating a cornea of an eye , the method comprising:measuring a profile of a posterior portion of the cornea;incising the cornea with a beam pulse profile based on the profile of the posterior portion.2. The method of claim 1 , wherein the cornea is treated so as to inhibit light scatter at a treated posterior surface of the treated cornea.3. The method of claim 1 , further comprising:measuring folds of the posterior portion of the cornea, wherein the beam pulse profile extends along the posterior portion in response to the folds to inhibit transecting lamella of the stroma.4. The method of claim 1 , wherein the posterior portion comprises an irregular posterior surface claim 1 , and wherein the beam pulse profile provides an irregular incision profile corresponding to the irregular posterior surface.5. A method as in claim 4 , wherein the irregular posterior surface corresponds to folds of stromal lamella of the cornea and wherein the irregular incision profile decreases transaction of the stromal lamella.6. The method of claim 5 , wherein a donor cornea comprises an irregular donor posterior surface corresponding to donor folds of donor stromal lamella of the donor cornea and wherein an irregular donor incision profile corresponding to the donor folds of the donor stromal lamella decreases transaction of the donor stromal lamella.7. The method of claim 1 , wherein the profile corresponds to folds of a Descemet's membrane of the cornea and wherein the incision profile ...

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Номер записи: 68
17-04-2014 дата публикации

Method for modifying the refractive index of ocular tissues

Номер: US20140107632A1
Автор: Krystel R. Huxlin, Wayne H. Knox
Принадлежит: UNIVERSITY OF ROCHESTER

A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss.

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Номер записи: 69
22-01-2015 дата публикации

Laser device and process for configuring such laser device

Номер: US20150025510A1
Автор: Christian Wuellner, Christof Donitzky, Klaus Vogler
Принадлежит: WaveLight GmbH

A process for configuring a laser device comprising: selecting a pulse length within a range from 1 ps to 1 ns; selecting a wavelength for the laser radiation within a range from 300 nm to 400 nm or within a range from 800 nm to 1100 nm; ascertaining a set of parameter values of the laser device that when the laser device is operated with these parameter values a two-dimensionally extensive separation of tissue of human corneal or lenticular tissue is achieved by stringing together local sites of damage, the set of parameter values including the selected pulse length, the selected wavelength, and values for at least one of the following parameters: a pulse energy, a pulse repetition rate, a fluence per radiation pulse, a number of pulses per site of damage, a scanning speed of a scanning apparatus of the laser device, and a focus diameter.

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Номер записи: 70
26-01-2017 дата публикации

CONFORMABLE THERAPEUTIC SHIELD FOR VISION AND PAIN

Номер: US20170023800A1
Автор: Alster Yair, Barragan Enrique, Carson Dean, Clarke Matt, de Juan, JR. Eugene, Levy Brian, MacFarlane K. Angela, Reich Cary J., Rimer Doug, Sutton Douglas, Tuan Ashley
Принадлежит:

A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. 1. A covering for an eye of a patient , the eye comprising a cornea , an epithelial defect , and an epithelium , the covering comprising:an inner portion, wherein the inner portion comprises silicone and is characterized by a center thickness from 50 μm to 250 μm, an oxygen permeability Dk of at least 450; andan outer portion coupled to the inner portion;wherein, when applied to an eye of a patient, the outer portion of the covering at least partially conforms to the cornea,wherein the inner portion provides a chamber between a posterior surface of the inner portion and the cornea in a region of the epithelial defect, andwherein the outer portion is configured so as to resist movement of the inner portion with the outer portion is placed on the eye.2. The covering of claim 1 , wherein the epithelial defect comprises an ablated stroma.3. The covering of claim 1 , wherein the chamber provides an environment configured to promote growth of the epithelium extending over the epithelial defect of at least about 6 mm across within about 2 days of a photorefractive keratectomy (PRK) ablation.4. The covering of claim 1 , wherein the inner portion has an ...

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Номер записи: 71
23-01-2020 дата публикации

OPTIMIZATION OF SPHERICAL ABERRATION PARAMETERS FOR CORNEAL LASER TREATMENT

Номер: US20200022838A1
Автор: Lemonis Sissimos
Принадлежит:

A method for determining spherical aberration parameters for a corneal laser treatment to treat presbyopia may include performing pupillometry to measure various actual pupil diameters of a patient from a photopic diameter to a mesopic diameter. An actual pupil center of the patient may also be measured. The measured pupil diameters and the pupil center may be used to customize the spherical aberration parameters to the eye of the patient for improved ocular results after treatment. 1. A method for optimization of spherical aberration parameters for corneal laser treatments , the method comprising:performing pupillometry on a patient subject to a corneal laser treatment to measure respective pupil diameters including: a mesopic diameter, a normal light diameter, an accommodative reading diameter, and a photopic diameter;calculating an outer diameter for the spherical aberration that is greater than the mesopic diameter;calculating an inner diameter for the spherical aberration associated with an amplitude of the spherical aberration that corresponds to the photopic diameter;calculating the amplitude of the spherical aberration according to a refraction that induces myopia;calculating a slope of the spherical aberration extending from the photopic diameter to the normal light diameter; andusing the spherical aberration calculated, including the outer diameter, the inner diameter, the amplitude, and the slope, performing the corneal laser treatment on the patient.2. The method of claim 1 , wherein performing the pupillometry further comprises determining a pupil center of the pupil claim 1 , and further comprising:calculating a center of the spherical aberration based on the pupil center.3. The method of claim 1 , wherein the corneal laser treatment is a presbyopia treatment.4. The method of claim 1 , wherein the corneal laser treatment is performed using a laser-assisted in situ keratomileusis (LASIK).5. The method of claim 1 , wherein calculating the slope of the ...

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Номер записи: 72
28-01-2021 дата публикации

System, method and material composition for use in correction of eye conditions

Номер: US20210022922A1
Автор: David Smadja, Jean Paul Lellouche, Rivka BEN ISHAY, Yifat HAREL, Zeev Zalevsky
Принадлежит: BAR ILAN UNIVERSITY

A system, technique and material composition for use in correction of eye condition are disclosed. The system comprising a processing utility and an etching utility. The processing utility comprises: correction pattern module configured for providing a selected two-dimensional pattern in according with input data indicative of vision impermanent of a user, and for generating operational instructions for forming said selected two-dimensional pattern on the surface of the cornea by said etching utility. The etching utility is configured to etching the selected patter on surface of the cornea of a user. The material composition comprises aqueous solution comprising a plurality of nanoparticles, said nanoparticles comprising maghemite nanoparticles wrapped by biocompatible protein chains. The material composition may be used as eye drops thereby allowing the nanoparticles to occupy etched region on the cornea, thereby maintaining correction of eye condition

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Номер записи: 73
02-02-2017 дата публикации

Apparatus for patterned plasma-mediated laser ophthalmic surgery

Номер: US20170027747A1
Автор: Dan E. Andersen, Daniel V. Palanker, David H. Mordaunt, Mark S. Blumenkranz
Принадлежит: Optimedica Corp

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

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Номер записи: 74
02-02-2017 дата публикации

LASER TREATMENT DEVICE

Номер: US20170027748A1
Автор: Bischoff Mark, EBERT Elke, FESTAG Karsten, LANG Carsten, Sticker Markus
Принадлежит:

An adapter for coupling a laser treatment device to an object for treatment. The adapter has an input side, which may be fixed relative to the laser treatment device, by a locking mechanism and which may be fixed to the object, for alignment of the object relative to the laser treatment device. A scanned laser beam is introduced on the input side, from the laser treatment device, along a beam path to the object with a reference structure. The reference structure lies on the beam path of the adapter and may be optically detected by means of the laser beam scanned over the region. 1. (canceled)2. An adapter for coupling an eye to be treated in ophthalmic surgery with a laser treatment device , the adapter comprising:an adapter input side, being fixable relative to the laser treatment device via a locking mechanism;an adapter beam path,a scanned region that is part of the adapter input side, wherein a laser beam, having been supplied to be scanned over the scanned region, is transmitted along the adapter beam path, wherein the adapter beam path starts at the scanned region and the laser beam passes through the scanned region and along the adapter beam path when being scanned during laser treatment; anda reference structure, the reference structure being located in the adapter beam path such that the reference structure can be illuminated by laser radiation being scanned over the scanned region, wherein the reference structure is adapted to absorb or reflect the laser radiation to make the reference structure optically detectable; andwherein the reference structure encodes information about the adapter.3. The adapter as claimed in claim 2 , wherein the information encoded by the reference structure includes an adapter ID.4. The adapter as claimed in claim 2 , wherein the information encoded by the reference structure includes an adapter type.5. The adapter as claimed in claim 2 , further comprising an adapter output side claim 2 , through which laser radiation supplied ...

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Номер записи: 75
02-02-2017 дата публикации

CORNEAL IMPLANT SYSTEMS AND METHODS

Номер: US20170027754A1
Автор: Muller David
Принадлежит:

A system for forming a corneal implant includes a cutting apparatus, which includes a laser source that emits a laser and optical elements that direct the laser. The system includes a controller implemented with at least one processor and at least one data storage device. The controller generates a sculpting plan for modifying a first shape of a lenticule formed from corneal tissue and achieving a second shape for the lenticule to produce a corneal implant with a refractive profile to reshape a recipient eye. The sculpting plan is determined from measurements relating to the lenticule having the first shape and information relating to a refractive profile for a corneal implant. The controller controls the cutting apparatus to direct, via the one or more optical elements, the laser from the laser source to sculpt the lenticule according to the sculpting plan to produce the corneal implant with the refractive profile. 1. A system for forming a corneal implant , comprising: a laser source that emits a laser; and', 'one or more optical elements that direct the laser from the laser source;, 'a cutting apparatus including [ measurements relating to the lenticule having the first shape, and', 'information relating to a refractive profile for a corneal implant, and, 'generate a sculpting plan for modifying a first shape of a lenticule formed from corneal tissue and achieving a second shape for the lenticule to produce a corneal implant with a refractive profile to reshape a recipient eye, the sculpting plan determined from, 'control the cutting apparatus to direct, via the one or more optical elements, the laser from the laser source to sculpt the lenticule according to the sculpting plan to produce the corneal implant with the refractive profile., 'a controller implemented with at least one processor and at least one data storage device, the controller configured to2. The system of claim 1 , wherein the measurements relating to the lenticule include three-dimensional ...

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Номер записи: 76
02-02-2017 дата публикации

SYSTEM FOR PERFORMING RETINA PHOTOSTIMULATION

Номер: US20170027755A1
Автор: Chang David B., Luttrull Jeffrey K., Margolis Benjamin W. L.
Принадлежит: Ojai Retinal Technology, LLC

A process for performing retinal phototherapy or photostimulation includes generating a laser light that creates a therapeutic effect to retinal and/or foveal tissues exposed to the laser light without destroying or permanently damaging the retinal or foveal tissue. The laser light is applied to a first treatment area of the retina. After a predetermined interval of time, within a single treatment session, the laser light is reapplied to the first treatment area of the retina. During the interval of time between the laser light applications to the first treatment area, the laser light is applied to one or more additional areas of the retina that is spaced apart from the first treatment area and one another. The laser light is repeatedly applied to each of the areas to be treated until a predetermined number of laser light applications to each area to be treated has been achieved. 122-. (canceled)23. A system for performing retinal photostimulation , comprising:a laser console generating a micropulsed laser light beam;an optical mask that the laser light beam passes through to optically shape the laser light beam;a coaxial wide-field non-contact digital optical viewing camera projecting the laser light beam to an area of a desired site for performing retinal photostimulation; anda mechanism that controllably moves the laser light beam during micropulse intervals to at least one other area of the desired site for performing retinal photostimulation, and subsequently returns the laser light beam to a previously treated area within a predetermined period of time during the same treatment session to reapply the laser light beam to that area.24. The system of claim 23 , wherein the laser light beam is controllably moved to achieve complete coverage of the desired site for performing retinal photostimulation.25. The system of claim 23 , wherein the laser light beam is selectively applied to disease markers on the desired site for performing retinal photostimulation.26. The ...

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Номер записи: 77
02-02-2017 дата публикации

METHOD AND APPARATUS FOR AUTOMATED PLACEMENT OF SCANNED LASER CAPSULORHEXIS INCISIONS

Номер: US20170027756A1
Автор: Angeley David G., Gooding Phillip H., Marcellino George R., Woodley Bruce
Принадлежит:

Systems and methods are described for cataract intervention. In one embodiment a system comprises a laser source configured to produce a treatment beam comprising a plurality of laser pulses; an integrated optical system comprising an imaging assembly operatively coupled to a treatment laser delivery assembly such that they share at least one common optical element, the integrated optical system being configured to acquire image information pertinent to one or more targeted tissue structures and direct the treatment beam in a 3-dimensional pattern to cause breakdown in at least one of the targeted tissue structures; and a controller operatively coupled to the laser source and integrated optical system, and configured to adjust the laser beam and treatment pattern based upon the image information, and distinguish two or more anatomical structures of the eye based at least in part upon a robust least squares fit analysis of the image information. 115-. (canceled)16. A system for cataract surgery on an eye of a patient , comprising:a. a laser source configured to produce a treatment beam comprising a plurality of laser pulses;b. an integrated optical system comprising an Optical Coherence Tomographer (OCT) coupled to a treatment laser delivery assembly such that the OCT and the treatment laser delivery assembly share at least one common optical element, the integrated optical system being configured to acquire image information pertinent to one or more targeted tissue structures and direct the treatment beam in a 3-dimensional pattern to cause breakdown in at least one of the targeted tissue structures;c. a patient support configured to maintain the eye of the patient within a range of the optical system; and 1) adjust the laser beam and treatment pattern based upon the image information,', '2) operate the OCT to perform one or more A-scans of at least one anatomical structure of the eye at each of a plurality of XY locations, thereby obtaining image information of a ...

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Номер записи: 78
04-02-2016 дата публикации

SYSTEM AND APPARATUS FOR TREATING THE LENS OF AN EYE

Номер: US20160030244A1
Автор: De Castro Jorge A., Downes George R., Frey Rudolph W., Gray Gary B., Kuszak Jerome R., Pape Dennis R.
Принадлежит: Lensar, Inc.

A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided apparatus for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern. 113-. (canceled)14. A system for delivering lasers to a natural crystalline lens of an eye and for obtaining stereo images of the natural crystalline lens of the eye comprising:a. a first laser that generates a therapeutic laser beam of a predetermined first wavelength;b. a second laser that generates a second laser beam of a predetermined second wavelength;c. a scanner optically associated with the first laser beam and the second laser beam and the camera; wherein the scanner has the capability to provide stereo pairs of images of portions of the natural crystalline lens of the eye by delivering the first laser beam and the second Laser beam and deliver a laser beam from the first laser to the natural crystalline lens of the eye, wherein the redetermined first wavelength and a beam size of the first laser beam are such that the first laser beam travels entirely through ha cornea of the eye without significantly affecting the cornea prior to being delivered to the natural crystalline lens; andd. camera that receives the first laser beam and the second laser beam from the scanner and generates a stereo pair of images.15. (canceled)16. A system for delivering a laser beam to a natural crystalline lens of an eye comprising:a. a laser for producing, a laser beam of a predetermined wavelength;b. an optical path for directing the laser beam from the ...

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Номер записи: 79
01-02-2018 дата публикации

METHOD AND APPARATUS FOR PERFORMING OPHTHALMIC PROCEDURES REMOVING UNDESIRABLE FEATURES USING LASER ENERGY

Номер: US20180028354A1
Автор: HEEREN TAMMO
Принадлежит:

A method and system perform an ophthalmic procedure on an eye having an optical path from the lens to the retina. An image of at least part of the eye is received in a data processing unit. The image includes the optical path. The data processing unit determines keep out zone(s) and identifies undesirable feature(s) based on the image. The keep out zone(s) include the retina. The data processing unit also selects one of the undesirable feature(s) for removal. At least part of the undesirable feature is outside of the keep out zone(s). Confirmation for removal of the undesirable feature is received in the data processing unit. In response to receiving the confirmation, a control unit controls a laser to perform laser removal the at least the portion of the undesirable feature without targeting any portion of the keep out zone(s). 1. A method for performing an ophthalmic procedure on an eye including a lens and a retina , the eye having an optical path from the lens to the retina , the method comprising:receiving an image of at least a portion of the eye in a data processing unit of an ophthalmic laser system including the data processing unit and a control unit, the portion of the eye including the optical path;determining, using the data processing unit, at least one keep out zone based on the image, the at least one keep out zone including the retina;identifying, using the data processing unit, at least one undesirable feature based on the image;selecting, using the data processing unit, an undesirable feature of the at least one undesirable feature for removal, at least a portion of the undesirable feature residing outside of the at least one keep out zone;receiving confirmation for removal of the undesirable feature in the data processing unit; andin response to receiving the confirmation, controlling a laser via the control unit to perform laser removal of the at least the portion of the undesirable feature without targeting any portion of the at least one keep ...

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Номер записи: 80
01-02-2018 дата публикации

INTEGRATED OPHTHALMIC SURGICAL SYSTEM

Номер: US20180028355A1
Автор: Raksi Ferenc
Принадлежит:

An ophthalmic surgical system includes a chassis comprising a laser source. The system includes a gantry coupled to the chassis. The position of the gantry is adjustable. The system includes a reference interface coupled to the gantry. The reference interface comprises an attachment interface at a distal portion of the reference interface, configured to couple to a patient interface for docking with an eye. The reference interface is configured to move to a first plate position proximal to the chassis and a second plate position distal from the chassis. The system further includes an optical head unit coupled to the reference interface. The optical head unit comprises a laser scanner and a beam splitter. The optical head unit is configured to move to a first head unit position near a proximal end of the reference interface and a second head unit position which is a lockable surgical position near a distal end of the reference interface. 1. An ophthalmic laser surgical system , comprising:a chassis comprising a pulsed laser source configured to generate a laser beam of laser pulses;a gantry coupled to the chassis, wherein the position of the gantry with respect to the chassis is adjustable; the reference interface comprises an attachment interface configured to couple to a patient interface for docking with an eye, the attachment interface located at a distal portion of the reference interface; and', 'the reference interface is configured to move to a first reference interface position in which the attachment interface is proximal to the chassis and a second reference interface position in which the attachment interface is distal from the chassis;, 'a reference interface coupled to the gantry, wherein [ a laser scanner configured to scan the scan the laser beam of pulsed laser pulses to a target region of an eye docked to the patient interface; and', 'a beam splitter configured to multiplex the scanned laser beam of pulsed laser pulses with an imaging beam path of an ...

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Номер записи: 81
29-01-2015 дата публикации

Second pass femtosecond laser for incomplete laser full or partial thickness corneal incisions

Номер: US20150032091A1
Автор: E. Valaski Teuma, Gary Gray
Принадлежит: Lensar Inc

A method for forming an incision in an eye, the method including performing a first pass of a first laser beam along a path within an eye, wherein after completion of the first pass there exists a residual uncut layer at an anterior surface of a cornea of the eye. The method further including performing a second pass of a second laser beam only along a portion of the path that contains the residual uncut layer, wherein after completion of the second pass, the residual uncut layer is transformed into a full complete through surface incision.

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Номер записи: 82
17-02-2022 дата публикации

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Номер: US20220047419A1
Автор: Bergt Michael, Bischoff Mark, Sticker Markus, Stobrawa Gregor, Wiechmann Martin
Принадлежит:

A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors. 1. (canceled)2. A method for laser based surgical correction of an eyesight defect in a patient's eye , wherein the eye comprises a cornea having an anterior corneal surface and corneal tissue located below the anterior corneal surface , the method comprising:creating a three dimensional (3D) cut within the cornea, the 3D cut confining a volume located within the cornea, isolating the volume within the cornea, and making the volume removable from the interior of the cornea, wherein the volume is sized such that removal of the volume from the corneal tissue below the anterior corneal surface changes a shape of the anterior corneal surface such that the eyesight defect is corrected or reduced,wherein creating the 3D cut comprises emitting pulsed laser radiation from a laser device and focusing the pulsed laser radiation to a three-dimensional pattern of target points in the cornea, wherein the target points are located in a 3D surface defining the 3D cut,wherein creating the 3D cut further comprises forming the 3D surface with two surface parts including an anterior surface part and a posterior surface part, wherein one of these two surface parts is located at a constant distance to from ...

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Номер записи: 83
17-02-2022 дата публикации

Combined Laser and Phacoemulsification System for Eye Surgery

Номер: US20220047421A1
Автор: HORVATH Christopher, VERA Vanessa I.
Принадлежит: Lensar, Inc.

Cataract surgery is in recent years more and more augmented and supported by the application of laser cuts in the eye tissue. Such laser systems are separate units from the phacoemulsification system units that are usually used for cataract extraction. The laser systems require the patient to be positioned under the laser unit and then being moved under the surgical microscope next to the phacoemulsification unit. The here described invention relates to systems combining several aspects of the laser system and the phacoemulsification system. In particular, this invention relates to combining at least some parts of the control system and the housing for both systems and thereby minimizing and optimizing setup time, operating room footprint, patient flow and cost. Furthermore the here disclosed invention relates to integrating the laser system under the surgical microscope and thereby significantly reducing the surgery setup and complexity. 1. A system for eye surgery , comprising a common controller to control both (a) a femtosecond laser system to cut a tissue structure of an eye with a laser beam; and (b) a phacoemulsification system to emulsify a lens within a capsule of an eye;a control system having a surgeon input interface that controls both (a) at least some parameters to operate the femtosecond laser system, and (b) at least some parameters to operate the phacoemulsification system: and wherein at least a portion of the femtosecond laser system is housed in a common housing with at least a portion of the phacoemulsification system.2. A system as in claim 1 , wherein the femtosecond laser system can be controlled to cut the tissue structure of the eye that includes lens capsule claim 1 , limbal relaxing incisions claim 1 , corneal incisions claim 1 , vitrious claim 1 , retina claim 1 , and anterior chamber.3. A system as in claim 1 , wherein the femtosecond system includes a laser engine and a laser delivery system.4. A system as in claim 3 , wherein the ...

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Номер записи: 84
17-02-2022 дата публикации

METHODS AND SYSTEMS FOR LASER ASSISTED TECHNOLOGY FOR MINIMALLY-INVASIVE AB-INTERNO GLAUCOMA SURGERY

Номер: US20220047422A1
Автор: CASTRO Ronen, Kaplan Eran
Принадлежит:

Some embodiments of the present disclosure relate to a method and system where a fiber optic probe is obtained. In some embodiments, the fiber optic probe comprises a distal end. In some embodiments, the fiber optic probe is introduced between an outer surface of an eye and an anterior chamber of an eye. In some embodiments, the fiber optic probe is advanced into one or more portions of the eye. In some embodiments, a plurality of pulses of laser radiation are delivered through a laser and into the eye. In some embodiments, the laser is disposed at a distal end of the fiber optic probe. In some embodiments, ocular tissue of the eye is ablated with the plurality of pulses of laser radiation. In some embodiments, the ablating generates a drainage channel that extends from the anterior chamber of the eye to the subconjunctival space of the eye. 1. A method comprising: 'wherein the fiber optic probe comprises a distal end;', 'obtaining a fiber optic probe,'}introducing the fiber optic probe between an outer surface of an eye and an anterior chamber of an eye;advancing the fiber optic probe across the anterior chamber of the eye so that the fiber optic probe is adjacent to or in contact with: the trabecular meshwork, Schwalbe's line, between the scleral spur and the sclerocorneal junction, or any combination thereof; 'wherein the laser is disposed at a distal end of the fiber optic probe;', 'delivering a plurality of pulses of laser radiation through a laser and into the eye;'} 'wherein the drainage channel extends from the anterior chamber of the eye to the subconjunctival space of the eye.', 'wherein the ablating generates a drainage channel, and'}, 'ablating ocular tissue of the eye with the plurality of pulses of laser radiation,'}2. The method of claim 1 , wherein the ablating is thermal ablating and the laser radiation is thermal laser radiation.3. The method of claim 1 , wherein the fiber optic probe is inserted into the eye directly through perforation by the ...

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Номер записи: 85
31-01-2019 дата публикации

Controlling a laser surgical device with a sensation generator

Номер: US20190029882A1
Автор: Peter Martin
Принадлежит: NOVARTIS AG

In certain embodiments, a system for controlling a laser device comprises a laser device, a distance meter, a haptic sensation generator, and a computer. The laser device generates a laser beam with a focal point. The distance meter measures a distance between the focal point and a target of an eye of a patient. The haptic sensation generator generates an acoustic field that projects a sensory pattern onto a user. The computer: receives the distance from the distance meter; determines the pattern corresponding to the distance according to a function in which the distance is a variable; and instructs the haptic sensation generator to generate the acoustic field that projects the determined pattern.

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Номер записи: 86
31-01-2019 дата публикации

SCANNING DEVICE

Номер: US20190029883A1
Автор: Bischoff Mark, Gerlach Mario, Hanft Marco, Muehlhoff Dirk
Принадлежит:

A scanning device for focusing a beam of rays in defined regions of a defined volume, comprising an input optics wherein the beam of rays penetrates first, having at least one first optical element; a focusing optics for focusing the beam of rays exiting from the input optics; and a deflecting device arranged between the first optical element and the focusing optics, for deflecting the beam of rays after it has passed through the first optical element, based on a position of the focus to be adjusted in lateral direction. In order to adjust the position of the focus of the beam of rays in the direction of the beam of rays, and optical element of the input optics can be displaced relative to the deflecting device. 1. (canceled)2. A surgical laser system including a scanning device for focusing a luminous beam into a selected range of an eye to be treated , the surgical laser system comprising:a femtosecond surgical laser source that produces the luminous beam;entrance optics following the femtosecond surgical laser source into which the luminous beam first enters comprising at least a first optical element;focusing optics by which the luminous beam emitted from the entrance optics is focused on or into the eye to be treated;a deflecting device arranged between the first optical element and the focusing optics that diverts a focus position of the luminous beam;the deflecting device comprising a first movable reflective element movable about a first axis configured to deflect the luminous beam in an X direction and a second movable reflective element movable about a second axis that is substantially orthogonal to the first axis configured to deflect the luminous beam in a Y direction; anda beam splitter, located between the deflecting device and the focusing optics; and in which the entrance optics and focusing optics are chromatically corrected over a spectral range of selected femtosecond pulses.3. The surgical laser system including a scanning device as claimed in ...

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Номер записи: 87
30-01-2020 дата публикации

SWEEPING OPTICAL SCANNER OF AN APPARATUS FOR CUTTING-OUT A HUMAN OR ANIMAL TISSUE

Номер: US20200030145A1
Автор: BAUBEAU Emmanuel, BERNARD Aurelien, MAUCLAIR Cyril, Romano Fabrizio
Принадлежит:

The present invention relates to an apparatus for cutting-out including a device for treating a L.A.S.E.R. beam generated by a femtosecond laser (), and positioned downstream from said femtosecond laser, the treatment device comprising: 1. An apparatus for cutting-out a human or animal tissue , such as a cornea or a lens , said apparatus including a femtosecond laser capable of sending a L.A.S.E.R. beam in the form of pulses and a device for treating the L.A.S.E.R. beam generated by the femtosecond laser , the treatment device being positioned downstream from said femtosecond laser , a shaping system positioned on the trajectory of said beam, for modulating the phase of the wave front of the L.A.S.E.R. beam so as to obtain a phase-modulated L.A.S.E.R. single-beam according to a modulation set value calculated for distributing the energy of the L.A.S.E.R. beam in at least two impact points forming a pattern in its focal plane,', 'an optical focusing system downstream from the shaping system, the optical focusing system comprising a concentrator module for focusing the phase-modulated L.A.S.E.R. beam in a focusing plane and a depth-positioning module for displacing the focusing plane into a plurality of cutting-out planes,', 'a sweeping optical scanner positioned between the concentrator module and the depth-positioning module for displacing the pattern in the cutting-out plane in a plurality of positions., 'wherein the treatment device comprises2. The apparatus according to claim 1 , which further comprises a control unit of the optical scanner for controlling the displacement of the pattern along a displacement path comprising at least one segment in the cutting-out plane.3. The apparatus according to claim 2 , wherein the control unit is programmed for controlling the activation of the femtosecond laser such that the distance between two adjacent positions of the pattern along a segment of the displacement path is greater than or equal to the diameter of an impact ...

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Номер записи: 88
09-02-2017 дата публикации

SYSTEM FOR NEUROPROTECTIVE THERAPY FOR GLAUCOMA

Номер: US20170035612A1
Автор: Chang David B., Luttrull Jeffrey K., Margolis Benjamin W. L.
Принадлежит: Ojai Retinal Technology, LLC

Providing neuroprotective therapy for glaucoma includes generating a micropulsed laser light beam having parameters and characteristics, including pulse length, power, and duty cycle, selected to create a therapeutic effect with no visible laser lesions or tissue damage to the retina. The laser light beam is applied to retinal and/or foveal tissue of an eye having glaucoma or a risk of glaucoma to create a therapeutic effect to the retinal and/or foveal tissue exposed to the laser light beam without destroying or permanently damaging the retinal and/or foveal tissue and improve function or condition of an optic nerve and/or retinal ganglion cells of the eye. 114-. (canceled)15. A system for providing glaucoma neuroprotective treatment , comprising:a laser console producing a micropulsed laser light beam having characteristics of providing a therapeutic effect to retinal tissue without permanently damaging the retinal tissue, the micropulsed laser light beam characteristics including a wavelength of 532 nm or greater and a duty cycle of less than 10%;an optical mask that the laser light beam passes through to optically shape the laser light beam;a coaxial wide-field non-contact digital optical viewing camera projecting the laser light beam to an area of a retina of an eye; andan optical scanning mechanism for controllably directing the light beam onto the retina to provide a therapeutic effect to the retinal tissue and improve at least one of optical nerve or retinal ganglion cell function.16. The system of claim 15 , wherein the laser console produces a laser light beam having a wavelength between 750 nm-1300 nm.17. The system of claim 16 , wherein the laser console produces a laser light beam having a wavelength of approximately 810 nm.18. The system of claim 15 , wherein the pulse length of the laser light beam is 500 milliseconds or less.19. The system of claim 15 , wherein the duty cycle of the laser light beam is 5% or less.20. The system of claim 15 , wherein ...

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Номер записи: 89
09-02-2017 дата публикации

METHOD FOR MODIFYING THE REFRACTIVE INDEX OF OCULAR TISSUES

Номер: US20170035613A1
Автор: Huxlin Krystel R., Knox Wayne H.
Принадлежит:

A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss. 1. A method for providing vision correction to a patient , the method comprising:(a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision;(b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and(c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens.2. The method of claim 1 , wherein the refractive index of the refractive structure differs from the cornea tissue outside of the focal region by 0.005 to 0.06.3. The method of claim 1 , further comprising verifying the vision correction provided by the refractive structures.4. The method of claim 2 , wherein the femtosecond laser pulses have a repetition rate from 10 MHz to 300 MHz ...

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Номер записи: 90
05-02-2015 дата публикации

Method and Apparatus for Patterned Plasma-Mediated Laser Trephination of the Lens Capsule and Three Dimensional Phaco-Segmentation

Номер: US20150038952A1
Автор: Andersen Dan E., Blumenkranz Mark S., Mordaunt David H., PALANKER Daniel V.
Принадлежит:

System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist. 120-. (canceled)21. A laser surgical system for making incisions in ocular tissues during a cataract surgical procedure , the system comprising:a laser system comprising a scanning assembly, a laser operable to generate a laser beam configured to incise ocular tissue;an imaging device configured to acquire point by point image data from locations distributed throughout a volume of a crystalline lens of the patient and construct one or more images of the patient's eye tissues from the image data, wherein the one or more images comprise an image of at least a portion of the crystalline lens; and ["operate the imaging device to generate image data for patient's crystalline lens;", 'process the image data to identify a location for each of one or more targets in the lens of the patient;', 'process the image data to determine a treatment scanning pattern for scanning a focal zone of the laser beam for performing a treatment at each location of the one or more targets; and', 'operate the laser and the scanning assembly to scan the focal zone of the laser beam in the treatment scanning pattern at each location of the one or more targets, wherein positioning of the focal zone is guided by the control system based on the location of the one or more targets., 'a control system operably coupled to the laser system and configured to22. The system of claim 21 , wherein the control system is configured automatically identify each location of the one or more targets based on the detection of an edge in the ...

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Номер записи: 91
08-02-2018 дата публикации

Method for Creating Incision to Improve Intraocular Lens Placement

Номер: US20180036117A1
Автор: Andersen Dan, Angeley David, BLUMENKRANZ Mark, Culbertson William, Marcellino George, Wiltberger Michael
Принадлежит:

A system and method for inserting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member. 17.-. (canceled)8. A system for surgery on a tissue of a patient's eye , comprising:a. an imaging system for generating image data of one or more structures of the eye;b. a light source for producing a laser beam;c. one or more scanning elements for directing a focal point of a laser beam produced by the light source to various portions of a lens capsule of the eye; andd. a controller operatively coupled to the imaging assembly, the light source and the one or more scanning elements, wherein the controller is programmed to operate the imaging system so as to acquire image data of the one or more structures of the eye, and operate the one or more scanning elements to guide a laser beam produced by the light source based at least in part on the image data to create a capsulotomy and at least one intraocular lens registration feature within the lens capsule of the eye, wherein, taken together, the capsulotomy and the at least one registration feature has rotational asymmetry.9. The system of claim 8 , wherein the at least one registration feature is capable of mating with a complimentary feature of an intraocular lens to orient the intraocular lens.10. The system of claim 8 , wherein the capsulotomy comprises the at least one lens ...

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Номер записи: 92
24-02-2022 дата публикации

Apparatus for patterned plasma-mediated laser ophthalmic surgery

Номер: US20220054308A1
Автор: Dan E. Andersen, Daniel V. Palanker, David H. Mordaunt, Mark S. Blumenkranz
Принадлежит: AMO DEVELOPMENT LLC

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

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Номер записи: 93
24-02-2022 дата публикации

CORNEAL LENTICULAR INCISIONS WITH TRANSITION ZONES IN LASER-ASSISTED OPHTHALMIC PROCEDURES

Номер: US20220054316A1
Автор: Bing Li, Chen Li, Fu Hong, Hill James, Khatibzadeh Nima, Malek Tabrizi Alireza, MEHTA-HURT Deepali, Villanueva Cynthia, Voorhees Andrew
Принадлежит:

In laser-assisted corneal lenticule extraction procedures, the lenticule incision profile includes anterior and posterior lenticule incisions, with one or more of the following features: plano transition zone outside the optical zone, to improve mating of anterior and posterior incision surfaces after lenticule extraction; shallow arcuate incisions above the anterior incision and near the lenticule edge, to improve surface mating; separate ring cut intersecting the anterior and posterior incisions in the transition zone, to reduce tissue bridges and minimize tear at the lenticule edges and facilitate easy lenticule extraction; larger posterior incision, which includes a pocket zone outside the lenticule edge, for better surface mating and bubble management during cutting; and a separate ring shaped pocket cut intersecting the pocket zone of the posterior incision, for bubble management. An entry cut can intersect either the pocket zone of the posterior incision or an entry extension zone of the anterior incision. 1. A method for forming a lenticule in a cornea of a patient's eye using an ophthalmic surgical laser system , comprising:operating the ophthalmic surgical laser system to generate a focused laser beam; andscanning the laser beam in the cornea to form an anterior lenticule incision and a posterior lenticule incision in the cornea,wherein the anterior lenticule incision includes a curved anterior optical zone, an anterior transition zone connected to and surrounding the anterior optical zone, and an anterior edge zone connected to and surrounding the anterior transition zone, wherein the posterior lenticule incision includes a curved posterior optical zone, a posterior transition zone connected to and surrounding the posterior optical zone, and a posterior edge zone connected to and surrounding the posterior transition zone, wherein the anterior optical zone and the posterior optical zone overlap each other in a top view along a direction parallel to an ...

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Номер записи: 94
07-02-2019 дата публикации

VISION CORRECTION SURGERY LASER ADAPTOR WHICH CREATES LASER BEAM NON-IRRADIATED REGION

Номер: US20190038373A1
Автор: JUNG Young Taek
Принадлежит:

The present invention relates to an adaptor of a laser for use in vision correction surgery that forms a laser beam non-irradiated region, of which an upper portion is coaxially aligned with an object lens of the laser, and a lower portion is coaxially aligned with a cornea of a patient, in order to set a position of the cornea of the patient with respect to the object lens of the laser. A pair of spaced shields for blocking the laser beam is provided on a non-refraction lens or refraction lens which is installed in the adaptor, the laser beam of the laser going through the non-refraction lens or refraction lens 1. An adaptor of a laser for use in vision correction surgery that forms a laser beam non-irradiated region , of which an upper portion is coaxially aligned with an object lens of the laser , and a lower portion is coaxially aligned with a cornea of a patient , in order to set a position of the cornea of the patient with respect to the object lens of the laser ,wherein a pair of spaced shields for blocking downward penetration of the laser beam is provided on a non-refraction lens or refraction lens which is installed in the adaptor, the laser beam of the laser going through the non-refraction lens or refraction lens.2. The adaptor of the laser according to claim 1 , wherein a focal point of the laser beam is three-dimensionally displaced to continuously draw dense helices on an inside of the cornea claim 1 , so that a flap surface and a lenticular surface which have a continuous spiral incision line are formed in a corneal stroma claim 1 ,an outer circumference of the lenticular surface intersects at any point inside an outer circumference of the flap surface, and the laser beam non-irradiated region is formed by the shield when a three-dimensional lenticule is incised from the corneal stroma, andthe laser beam non-irradiated region is formed on any one of the incision line of the flap surface which is positioned between outer circumferential incision lines ...

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Номер записи: 95
07-02-2019 дата публикации

INTRODUCING BUBBLES TO IMPROVE CORNEA RESHAPING WITHOUT THE CREATION OF A FLAP

Номер: US20190038464A1
Автор: Deng Li, Siegele Nicholas S., Suckewer Syzmon
Принадлежит:

Ultra-short pulsed laser radiation is applied to a patient's eye to create a row of bubbles oriented perpendicular to the axis of vision. The row of bubbles leads to a region of the eye to be ablated. In a second step, a femtosecond laser beam guided through the row of bubbles converts it to a channel perpendicular to the axis of vision. In a third step, a femtosecond laser beam is guided through the channel to ablate a portion of the eye. Using a femtosecond laser with intensity in the range of 10-10W/cmfor the second and third steps facilitates multi-photon ablation that is practically devoid of eye tissue heating. Creating bubbles in the first step increases the speed of channel creation and channel diameter uniformity, thereby increasing the precision of the subsequent multi-photon ablation. 1. A method of removing material from an internal portion of organic tissue , comprising:creating a first row of bubbles below the surface of the organic tissue with a first laser beam, wherein all of the bubbles in the first row of bubbles are linearly aligned;creating a channel through the linearly aligned first row of bubbles with a second laser beam; andmulti-photon ablating material located along or at the end of the channel with the second laser beam.2. The method of wherein the channel is created from 10seconds to 10seconds after the first row of bubbles is created.3. The method of wherein the first laser beam creating the first row of bubbles has a pulse intensity of from 10to 10W/cm; the second laser beam creating the channel through the first row of bubbles has a pulse intensity of from 10to 10W/cm; and the second laser beam ablating the material has a pulse intensity from 10to 10W/cm.4. The method of wherein the first laser beam creating the first row of bubbles has a pulse energy of from 1 to 10 μJ; the second laser beam creating the channel through the first row of bubbles has a pulse energy of from 0.1 mJ to 1 mJ; and the second laser beam ablating the material ...

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Номер записи: 96
06-02-2020 дата публикации

NONLINEAR COLLAGEN CROSSLINKING USING A SINGLE, AMPLIFIED, FEMTOSECOND LASER PULSE

Номер: US20200038239A1
Автор: Bradford Samantha, Brown Donald J., Jester James V., Juhsa Tibor, Mikula Eric
Принадлежит:

A laser beam delivery system including an amplified femtosecond (FS) laser device coupled to a nonlinear optical parametric amplifier (NOPA) configured to select a FS laser wavelength and to amplify input amplified femtosecond (FS) laser pulses of from 700 to 2500 nm to generate a single, parametrically amplified output FS pulse having a pulse energy of from 0.1-100 μJ, wherein the NOPA uses an average power of below 46.1 mW to amplify the input FS laser pulses. Also disclosed is a method of nonlinear optical photodynamic irradiation of a target. 1. A laser beam delivery system comprising an amplified femtosecond (FS) laser device coupled to a nonlinear optical parametric amplifier (NOPA) configured to select a FS laser wavelength and to amplify input amplified femtosecond (FS) laser pulses of from 700 to 2500 nm to generate a single , parametrically amplified output FS pulse having a pulse energy of from 0.1-100 μJ , wherein the NOPA uses an average power of below 46.1 mW to amplify the input FS laser pulses.2. The laser beam delivery system according to claim 1 , wherein the amplified FS laser device is configured to provide a repetition rate of 5 kHz to 50 kHz pulses.3. The laser beam delivery system according to claim 1 , wherein the NOPA is configured to parametrically amplify 760 nm pulses.4. The laser beam delivery system according to claim 1 , wherein the system is configured to focus 760 nm light with a variable 0.1-0.3 numerical aperture (NA) objective.5. The laser beam delivery system according to claim 1 , wherein the NOPA is configured to provide a single output pulse of about 2 μJ pulse energy having an average power of about 12 mW or less.6. The laser beam delivery system according to claim 1 , wherein the system comprises a tracker that automatically monitors position of a subject or a tissue so that the device is able to compensate for movement of the subject or tissue.7. A method of nonlinear optical photodynamic irradiation of a target claim 1 , ...

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Номер записи: 97
15-02-2018 дата публикации

METHOD FOR PATTERNED PLASMA-MEDIATED MODIFICATION OF THE CRYSTALLINE LENS

Номер: US20180042715A1
Автор: Culbertson William, Friedman Neil, Gooding Phillip, Schuele Georg, Seibel Barry
Принадлежит:

A method of treating a cataractous lens of a patient's eye includes generating a light beam, deflecting the light beam using a scanner to form a treatment pattern, delivering the treatment pattern to the lens of the patient's eye to create a plurality of cuts in the form two or more different incisions patterns within the lens to segment the lens tissue into a plurality of patterned pieces, and mechanically breaking the lens into a plurality of pieces along the cuts. A first incision pattern includes two or more crossing cut incision planes. A second incision pattern includes a plurality of laser incision each extending along a first length between a posterior and an anterior surface of the lens capsule. 13-. (canceled)4. A method of treating a cataractous lens of a patient's eye , comprising:a. generating a light beam;b. deflecting the light beam using a scanner to form a treatment pattern of the light beam;c. delivering the treatment pattern to the lens of the patient's eye to create a plurality of cuts in the lens in the form two or more different incision patterns within the lens to segment the lens tissue into a plurality of patterned pieces, the incision patterns comprising:a first incision pattern comprising a plurality of laser incision planes each extending along a first length between a posterior and an anterior surface of the lens capsule, wherein the plurality of the laser incision planes of the first treatment pattern comprise two or more crossing cut incision planes; anda second incision pattern comprising one or more laser incisions, each extending along a first length between a posterior and an anterior surface of the lens capsule; andd. mechanically breaking the lens into a plurality of pieces along the cuts.5. The method of claim 4 , wherein the crossing cut incisions do not pass through the center of the lens as viewed from a posterior to an anterior position along the optical axis.6. A method of treating a cataractous lens of a patient's eye ...

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Номер записи: 98
15-02-2018 дата публикации

Method for patterned plasma-mediated modification of the crystalline lens

Номер: US20180042716A1
Автор: Barry Seibel, Georg Schuele, Neil Friedman, Phillip Gooding, William Culbertson
Принадлежит: Optimedica Corp

A method of treating a lens of a patient's eye includes generating a light beam, deflecting the light beam using a scanner to form a treatment pattern of the light beam, delivering the treatment pattern to the lens of a patient's eye to create a plurality of cuts in the lens in the form of the treatment pattern to break the lens up into a plurality of pieces, and removing the lens pieces from the patient's eye. The lens pieces can then be mechanically removed. The light beam can be used to create larger segmenting cuts into the lens, as well as smaller softening cuts that soften the lens for easier removal.

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Номер записи: 99
15-02-2018 дата публикации

EPITHELIAL ABLATION SYSTEMS AND METHODS

Номер: US20180042771A1
Автор: Chernyak Dimitri, Logan Benjamin, MEHTA-HURT Deepali
Принадлежит: AMO Development, LLC

Systems and methods to treat a region of a cornea of an eye having an epithelial layer disposed over a stromal layer. Exemplary techniques include the administration of epithelial sequence ablation laser pulses and stromal sequence ablation laser pulses to the eye. A treatment laser generates a laser beam for ablation of eye tissue, and a movable scan component scans the laser beam over the region. A processor system is coupled to the laser and the movable scan component, and the processor system is configured to arrange pulses of laser beam to treat the epithelial and stromal layers of the region. 1. A method for treating a region of a cornea of an eye using a laser , the region of the cornea including an epithelial layer and a stromal layer , the method comprising:receiving an epithelial thickness map corresponding to the eye;receiving an epithelial basis data corresponding to an epithelial laser pulse ablation profile;ablating the epithelial layer with a first epithelial arrangement of laser beam pulses based on the epithelial thickness map and the epithelial basis data;receiving a crossover signal; andterminating the first epithelial arrangement of laser beam pulses in response to the crossover signal.2. The method of claim 1 , further comprising:receiving second epithelial basis data corresponding to a second epithelial laser pulse ablation profile;after terminating the first epithelial arrangement of laser beam pulses, ablating the epithelial layer with a second epithelial arrangement of laser beam pulses based on the epithelial thickness map and the second epithelial basis data.3. The method of claim 2 , wherein ablating the epithelial layer with the second epithelial arrangement of laser beam pulses is performed in response to inputs received from a human operator.4. The method of claim 2 , wherein the first epithelial arrangement of laser beam pulses has a first laser beam pulse repetition rate and the second epithelial arrangement of laser beam pulses has ...

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