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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 5999. Отображено 100.
27-06-2014 дата публикации

Устройство для управляемого нагрева тканей, сосудов и полостей человека и животных

Номер: RU0000142663U1
Автор: Генри МЕЕР
Принадлежит: НОВА ТЕРМА

1. Устройство, полностью или частично имплантируемое с целью передачи тепла в полость, ткань или сосуды отличающееся тем, что- оно представляет собой медный изолированный провод (1), за исключением концов, по крайней мере, на часть которого устанавливается резистивная трубка (5) обладающая электрическим сопротивлением более 20 мкОм/см,- медный провод (1) на дистальном конце (3) имеет контакт с упомянутой трубкой, в то время как проксимальный конец обладает возможностью быть соединенным с источником тока (9),- трубка покрыта на части своей длины одним подвижным проксимальным цилиндром (6), на проксимальном конце способным быть закрепленным на трубке (5), указанный цилиндр (6) обладает электрическим сопротивлением ниже 20 мкОм/см,- подвижный проксимальный цилиндр (6) и проксимальный конец медного провода (1) способны быть подключенными к источнику тока (9.)2. Устройство по п.1, отличающееся тем, что трубка (5) закреплена на проводе (1), только на дистальном конце указанного провода, на длину в пределах 5 см,3. Устройство по п.1, отличающееся тем, что трубка (5) закреплена микрообжатием,4. Устройство по п.1, отличающееся тем, что оно снабжено подвижными дистальными цилиндрами (7, 8), оснащенными на поверхности пористым носителем, выделяющим активное вещество,5. Устройство по п.1, отличающееся тем, что оно снабжено подвижными дистальными цилиндрами (7, 8), поверхность которых снабжена радиоактивным продуктом для терапии и локализации,6. Устройство по п.1, отличающееся тем, что трубка (5) выполнена из материала, выбранного из группы, включающей сталь, нержавеющую сталь, нитинол или титан,7. Устройство по п.1, отличающееся тем, что медный провод (1) изолир� РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 142 663 U1 (51) МПК A61B 18/08 (2006.01) A61F 7/12 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ТИТУЛЬНЫЙ (21)(22) Заявка: ЛИСТ ОПИСАНИЯ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ 2012140515/14, 04.03.2011 (24) Дата начала отсчета срока действия патента: 04.03.2011 (72) ...

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Номер записи: 1
19-01-2012 дата публикации

Method for transurethral delivery of thermal therapy to tissue

Номер: US20120016273A1
Автор: Chris J. Diederich
Принадлежит: UNIVERSITY OF CALIFORNIA

An apparatus for applying thermal energy to a prostate gland, comprising a support tube having a longitudinal passageway, a power lead channeled through the longitudinal central passageway and an ultrasound crystal disposed around at least part of the support tube. The ultrasound crystal is coupled to the power lead which provides the power to energize the ultrasound crystal and generate ultrasound energy providing thermal therapy to the prostate gland. The ultrasound crystal further includes inactivated portions for reducing ultrasound energy directed to the rectal wall of the patient. A sealant is disposed in contact with the ultrasound crystal allowing vibration necessary for efficient ultrasound energy radiation for the thermal therapy of the prostate gland.

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Номер записи: 2
16-02-2012 дата публикации

Head coller

Номер: US20120041526A1
Автор: Johan Stormby
Принадлежит: Dignitana AB

A head cooler ( 10 ) comprises a thermal exchange cap ( 11 ) and an outer insulating cover ( 12 ) to be arranged on a patient's head. The cap ( 11 ) has a channel system ( 31, 32 ) for a cooling fluid forming an inside heat exchange surface to be applied on said head for cooling the head. The thermal exchange cap ( 11, 60 ) is adjustable and/or adaptable to compensate for a discrepancy in shape and size between the inside surface of the head cooler ( 10 ) and the head. The head cooler ( 10 ) may further comprise an eyebrow cooler ( 140 ) for cooling the area of the eyebrows. The head cooler ( 140 ) is used in medicine. A method for preventing hair loss of a patient is provided by arranging the head cooler ( 10 ) on the head of said patient.

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Номер записи: 3
26-04-2012 дата публикации

System for detection and treatment of infection or inflamation

Номер: US20120101403A1
Автор: Levi Emmerik A. Dewaegenaere
Принадлежит: WAEGENER INTERRNATIONAL AG

The invention provides for a system for visualizing a medical treatment of a human or animal body part. The system has means for thermal treatment of the body part, means for determining the temperature distribution on the body part, and means for identifying the location of a particular temperature determined on the body part. Further, a method for visualizing the temperature characteristics of a human or animal body part is provided. The method has the steps of comparing a first temperature distribution data set of the surface of the body part with a second temperature distribution data set of the surface of the body part, wherein the first temperature distribution data set is determined before and the second temperature distribution data set is determined after a thermal treatment of the body part, and visualizing the temperature distribution data sets of the body part. Furthermore, a computer program product is provided. The computer program product has one or more computer readable media having computer executable instructions for actuating and controlling the steps of the method discussed hereinbefore.

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Номер записи: 4
10-05-2012 дата публикации

Apparatus utilizing a guide wire to maneuver heating element and probe for treating damaged spinal discs

Номер: US20120116377A1
Автор: Elizabeth Ann Snoderly
Принадлежит: Individual

The advantages of this invention are provided by a surgical tool for repairing a damaged spinal disc of a patient comprising: a catheter having a proximal end and a distal end; a guide wire contained within the catheter so that when the guide wire is pulled, the catheter will flex into a non linear shape allowing it to be steered once inserted in the patient; a heating element carried by the catheter, probe or heating member, and connected to an power source 45 (external or not) so that the heating element can be activated and provide heat to treat a disk; a probe that extends from the catheter so that the probe can be extended out of the catheter; and, a grasping member that can from the distal end of the catheter.

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Номер записи: 5
10-05-2012 дата публикации

Automated Therapy System and Method

Номер: US20120116487A1
Автор: Amit Rajguru, Christopher Hermanson, Daniel Rogers Burnett, Gregory Hall
Принадлежит: Velomedix Inc

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

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Номер записи: 6
28-06-2012 дата публикации

Cold/hot therapy device with temperature control

Номер: US20120165908A1
Автор: Bo-Min Shih, Chun-Che Hsieh, Hong-Sen Kou, Hsueh-Erh Liu, Ji-Jen Lee
Принадлежит: Tatung Co Ltd, Tatung University

A cold/hot therapy device with temperature control includes a housing, a pump, a cooling chip, a cooling head, a cooling fin, and a bag. The pump, the cooling chip and the cooling head are fixedly arranged in the accommodating chamber of the housing. The cooling chip includes a cool-effecting surface and a cooling surface. The cooling head is adjacent to the cool-effecting surface, and includes a water inlet and a water outlet, where the water inlet communicates with the pump outlet. The cooling fin is fixedly arranged on the cooling surface of the cooling chip, and is positioned in the hollow passage of the housing. The bag includes an inlet tube and an outlet tube, where the inlet tube communicates with the water outlet of the cooling head, and the outlet tube communicates with the pump inlet. Accordingly, a cold or hot therapy function can be achieved.

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Номер записи: 7
05-07-2012 дата публикации

Cooled surface for animals

Номер: US20120167607A1
Автор: Stephen R. Callender
Принадлежит: Individual

In the embodiment of my invention, a cooled surface is provided for a dog or other animal to lie upon. The cooled surface is a refrigerated surface. In the embodiment, the surface is the exterior surface of a thermally conductive plate that is one wall of a refrigerated space.

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Номер записи: 8
05-07-2012 дата публикации

Device for Applying Cold Therapy to Feet

Номер: US20120172958A1
Автор: Kenneth C. Snyder
Принадлежит: Individual

A device for applying cold therapy to the foot of a wearer is disclosed. The device comprises a foot pad having a premolded configuration for directly contacting the bottom of the foot and surrounding heel area. The foot pad includes a heel portion sized to receive and surround the heel of the foot. The foot pad also includes a raised and contoured arch portion positioned to lie beneath and place localized pressure on the arch of the foot where the plantar fascia and tendons of the foot are located. The entire foot pad is formed of an ice pack that includes a container or shell for receiving and containing a substance capable of maintaining an extremely low temperature for an extended period of time during application to the foot. The device also includes a securement mechanism that is arranged for engaging the foot pad to the bottom of the wearer's foot.

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Номер записи: 9
12-07-2012 дата публикации

Device and Method for the Reduction of Pain Associated With Needle Sticks

Номер: US20120179099A1
Автор: Amy L. Baxter, Louis A. Calderon
Принадлежит: MMJ Labs LLC

A device that is used to reduce the pain of a needle stick to a person, the device having a casing containing a vibratory device and a temperature reducing device, and a method for using the device to reduce the pain of a needle stick by applying both thermal and vibration analgesia to a subject during a needle stick.

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Номер записи: 10
30-08-2012 дата публикации

Central Nervous System Treatment Device and Methodology

Номер: US20120221082A1
Автор: Rohit Khanna
Принадлежит: Individual

The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid.

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Номер записи: 11
27-09-2012 дата публикации

Wrap around cooling apparatus or assembly

Номер: US20120245662A1
Автор: George Page
Принадлежит: Individual

A compartmentalized wrap around cooling element, assembly, or device for cooling relief or swelling may be provided. The compartmentalized wrap may include a series of poly-vinyl alcohol dividers to provide distinctly separate cooling sections, for long lasting cooling relief. Tube connector joints, tube loops, button snaps, and Velcro connectors may provide a secure means for forming a wrap around or loop, to encircle an area multiple times. An encasement design may provide an alternative means of securing the wrap to a large area, such as an adult head.

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Номер записи: 12
11-10-2012 дата публикации

Disposable breast pad

Номер: US20120259303A1
Автор: Marcia Angela Carter
Принадлежит: Individual

The present invention is referred to a nursing breast pad, comprising a circular pad including a front garment facing surface and a rear wearer facing surface attached to each other by a peripheral flange. The space between the garment facing surface and the wearer facing surface contains a liquid chemical and a powder chemical that, when mixed together, can produce an endothermic cooling action. The liquid chemical is contained within a flexible bag that, when squeezed by the user, causes the bag to burst so that the two chemicals can mix.

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Номер записи: 13
15-11-2012 дата публикации

Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject

Номер: US20120289761A1
Автор: Edward K. Y. Jung, Edward S. Boyden, Elizabeth A. Sweeney, Eric C. Leuthardt, Lowell L. Wood, JR., Muriel Y. Ishikawa, Roderick A. Hyde, Stephen L. Malaska
Принадлежит: SEARETE LLC

Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, wherein at least a portion of the one or more cooling elements is configured to be implantable, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.

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Номер записи: 14
15-11-2012 дата публикации

Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject

Номер: US20120289763A1
Автор: Edward K.Y. Jung, Edward S. Boyden, Elizabeth A. Sweeney, Eric C. Leuthardt, Lowell L. Wood, JR., Muriel Y. Ishikawa, Roderick A. Hyde, Stephen L. Malaska
Принадлежит: SEARETE LLC

Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more passive cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, wherein at least a portion of the one or more passive cooling elements is configured to be implantable, and wherein the one or more passive cooling elements includes a first portion configured to be in association with the one or more tissues to be cooled, and a second portion configured to be placed in association with one or more tissues adjacent to an external epidermal tissue of the vertebrate subject.

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Номер записи: 15
06-12-2012 дата публикации

Device for Cooling Persons

Номер: US20120304678A1
Автор: Petra Buck-Heitmann
Принадлежит: Individual

Device for cooling persons comprises a housing, which extends from an inlet end to an outlet end, and a snow generator, which opens out at the inlet end of the housing. A snow outlet is provided at the outlet end of the housing and a swirling module, which the snow particles generated by the snow generator pass on their way from the inlet end to the outlet end of the housing, is provided in the housing.

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Номер записи: 16
10-01-2013 дата публикации

Method of Inducing Thermogenesis by Manipulating the Thermoregulatory Status of a Human

Номер: US20130013037A1
Автор: Jason K. Adams
Принадлежит: Individual

This invention provides methods and devices for decreasing the core temperature of a human to cause weight loss. The methods involve contacting the body or a portion of the body with a cooling medium in a sealable chamber to induce a decrease in the core temperature.

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Номер записи: 17
17-01-2013 дата публикации

Device For Administering Heat To A Human Or Animal Tissue, Vessel Or Cavity

Номер: US20130018257A1
Автор: Henri Mehier
Принадлежит: NOVA THERMA

Device for administering heat to a cavity, tissue or vessel, characterised in that it takes the form of an insulated copper wire over the length of which is crimped a tube having a resistivity of more than 20 μΩ·cm, the copper wire ( 1 ) is in contact with the said tube at its distal extremity, the tube is enclosed over part of its length by at least one movable cylinder having an electrical resistance of less than 20 μΩ·cm, and the movable cylinder and the copper wire have means for connection to a current generator.

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Номер записи: 18
14-03-2013 дата публикации

Tissue treatment methods

Номер: US20130066309A1
Автор: Mitchell E. Levinson
Принадлежит: Zeltiq Aesthetics Inc

Methods are provided herein for affecting a region of a subject's body, comprising exposing the region to a cooling element under conditions effective to cool subcutaneous adipose tissue in said region; and increasing the blood flow rate to the cooled tissue by exposing the tissue to an energy source. Methods are also provided for treating subcutaneous adipose tissue in a region of a subject's body, comprising exposing said region to a cooling element under conditions effective to cool said tissue; and exposing the tissue to an energy source to increase the blood flow rate to the cooled tissue, thereby stimulating reperfusion in, and/or causing an ischemia-reperfusion injury to, the cooled tissue.

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Номер записи: 19
21-03-2013 дата публикации

CEREBRAL LOCAL PORTION COOLING PROBE AND CEREBRAL FUNCTION MAPPING DEVICE

Номер: US20130072776A1
Автор: Fujii Masami, FUJIOKA Hiroshi, Kajiwara Koji, Nomura Sadahiro, Saito Takashi, Suzuki Michiyasu, Yoshikawa Koichi
Принадлежит: YAMAGUCHI UNIVERSITY

A cerebral local portion cooling probe is composed so that a handheld module includes a Peltier device and a coolant liquid circulating part arranged so as to contact with the Peltier device and wirings, conduits and a heat radiating part are connected to this handheld module. Circulation of coolant liquid and operation of the Peltier device are implemented by means of a control unit, then the tip end of the handheld module is caused to contact with a cerebral local portion to be cooled and a state of the cerebral local portion is monitored in accordance with responses to the cooling. A cerebral function mapping device comprises a mapping module in which a plurality of cooling modules are arranged, each cooling module including a Peltier device and a coolant liquid circulating part in a manner similar to that of the cerebral local portion cooling probe. 1. A cerebral local portion cooling probe , comprising:a handheld module having a tubular casing and cooling means and temperature detecting means which are provided in the tubular casing at a tip end thereof; anda cooling control unit controlling temperature of a local portion of a cerebral surface to a predetermined temperature in accordance with temperature detection signal from the temperature detecting means, with a tip end of the handheld module being caused to contact with a cerebral local portion to cool the cerebral surface to the predetermined temperature thereby monitoring a state of the cerebral local portion,wherein the cooling means provided in the tubular casing at the tip end thereof is a Peltier device, a coolant liquid circulating part is provided so as to contact with the heat generating surface on the rear side of the Peltier device and the coolant liquid circulating part and a heat radiating part provided externally of the handheld module are coupled by conduits to circulate coolant liquid and radiate heat,wherein a metal plate is provided at the front surface of the Peltier device and exposed as ...

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Номер записи: 20
21-03-2013 дата публикации

Patient temperature control catheter with outer sleeve cooled by inner sleeve

Номер: US20130073014A1
Автор: Alex L. Lim, Jeremy T. Dabrowiak, Richard A. Helkowski, Venkata Vishnu Gurukula
Принадлежит: Zoll Circulation Inc

A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.

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Номер записи: 21
21-03-2013 дата публикации

METHODS AND DEVICES FOR NON-INVASIVE CEREBRAL AND SYSTEMIC COOLING ALTERNATING LIQUID MIST/GAS FOR INDUCTION AND GAS FOR MAINTENANCE

Номер: US20130073015A1
Автор: Rozenberg Allan
Принадлежит:

Methods for cerebral and systemic cooling via a patient's nasopharyngeal cavity are described. In one method, a cooling assembly is inserted into a nasal cavity through a patient's nostril. A substantially dry gas is delivered through a lumen of the catheter onto the surface of the patient's nasal cavity. Evaporative heat loss cools the patient's nasal cavity. If additional cooling is needed, a liquid coolant is delivered through a separated lumen of the catheter. The liquid coolant is nebulized at a plurality of delivery ports on the distal end of the catheter and is delivered onto the surface of the patient's nasal cavity in combination with the dry gas. The dry gas enhances evaporation of the nebulized coolant and additional cooling is provided from the evaporative heat loss of the liquid coolant. 1. A method for cerebral cooling , comprising the steps of:inserting an elongate member into a nasal cavity of a patient through a patient's nostril, the elongate member comprising a proximal end, a distal end, a first lumen extending therebetween, and a plurality of ports in fluid communication with the first lumen;delivering a nebulized liquid coolant and a substantially dry gas in combination onto a surface of the patient's nasal cavity through the plurality of ports in the elongate member for a period of between about 10 minutes to 9 hours; anddelivering a substantially dry gas substantially free of liquid onto a surface of the patient's nasal cavity through the plurality of ports in the elongate member for a period of between about 10 minutes to 240 hours,wherein the liquid coolant is nebulized at the plurality of ports within the nasal cavity and wherein the gas enhances evaporation of the liquid coolant from the nasal cavity to reduce the cerebral temperature of the patient.2. The method of claim 1 , wherein the cerebral temperature of the patient is reduced by between about 0.1 to 5.0° C./hour by evaporation of the liquid coolant in the nasal cavity.3. The ...

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Номер записи: 22
21-03-2013 дата публикации

Bacterial Cellulose-Based Ice Bags and the Production Method Thereof

Номер: US20130073019A1
Автор: Zhong Chunyan
Принадлежит:

This invention relates to bacterial cellulose-based ice bags and their production methods thereof. Bacterial cellulose membranes used in the present invention are produced through the fermentation of cellulose-producing microorganisms. Ice bags with three sealed sides and one open side are made from water-impermeable (under room temperature and normal atmospheric pressure) bacterial cellulose membranes. The bags are filled with filler materials and then sterilized at 120 degrees C. for 30 minutes and sealed aseptically. The use of bacterial cellulose as the packaging material solves the problems associated with conventional ice bags. The advantages of the present invention include: no condensation at the bag surface, smaller temperature changes during the course of application, and longer lasting ice therapy session. In addition, bacterial cellulose membrane is safe and non-toxic, and has excellent biocompatibility, plasticity and higher mechanical strength, making it an ideal packaging material for ice bags. 1) A bacterial cellulose ice bag of which the packaging material is made of bacterial cellulose membranes.2) The production method for the bacterial cellulose ice bag in consists of the following steps:a) Selection of a cellulose-producing microorganism as starting culture for the fermentation of bacterial cellulose membranesb) Making an ice bag according the shape of the affected area with three sealed side and one open side from water-impermeable cellulose membranes (under normal room temperature and pressure) with appropriate mechanical strengthc) Filling the bag with filler materials and then sterilizing at 120 degrees C. for 30 minutes and sealing the bag aseptically.3) The microorganism in for the production of bacterial cellulose ice bag is Gluconacetobacter xylinum 323 strain.4) The filling materials in are cooling agent claim 2 , a mixture of cooling agent and thickener claim 2 , a mixture of cooling agent and distilled water claim 2 , or a mixture of ...

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Номер записи: 23
28-03-2013 дата публикации

Grounded Pressure Cooling

Номер: US20130079854A1
Автор: Peter Z. Wasowski
Принадлежит: VASPER SYSTEMS LLC

A pressurized garment has cuffs for encircling a human subject, each cuff having ports for cooling and grounding unit controlling the pressure and temperature of the coolant, where the pressurization and cooling may use common or separate cuff ports. The cuff has a coolant circulating having a temperature and pressure selected to provide therapy to a subject in need thereof. The cuffs may be applied to the upper arms and upper thighs of a subject in need of improved vitality.

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Номер записи: 24
28-03-2013 дата публикации

Patient temperature control catheter with helical heat exchange paths

Номер: US20130079855A1
Автор: Alex L. Lim, Jeremy T. Dabrowiak, Richard A. Helkowski, Venkata Vishnu Gurukula
Принадлежит: Zoll Circulation Inc

A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.

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Номер записи: 25
28-03-2013 дата публикации

Transatrial patient temperature control catheter

Номер: US20130079858A1
Автор: Alex L. Lim, Jeremy T. Dabrowiak, Richard A. Helkowski, Venkata Vishnu Gurukula
Принадлежит: Zoll Circulation Inc

A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.

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Номер записи: 26
04-04-2013 дата публикации

GASTRIC, CUTANEOUS, OR PERITONEAL DELIVERY OF FROZEN MIST TO INDUCE THERAPEUTIC HYPERTHERMIA

Номер: US20130085554A1
Автор: Belson Amir
Принадлежит: THERMOCURE, INC.

Peritoneal heat exchange provides the benefit of extremely rapid cooling of the patient's target organs such as the heart and brain as well as facilitating global patient body temperature reduction to therapeutically effective temperatures. The heat exchange medium of the present invention is a chilled gaseous fluid suspension of frozen ice particles. 1. A method for cooling a patient , said method comprising:generating a flowing gas stream having entrained frozen solid particles; andpassing the flowing gas stream over a body surface which is not part of the patient's respiratory system, wherein the solid particles melt to absorb body heat to lower the patient's body temperature.2. A method as in claim 1 , wherein the body surface is in a body cavity.3. A method as in claim 2 , wherein the body cavity is an abdominal cavity or a stomach.4. A method as in claim 3 , wherein passing comprises introducing the flow gas stream through an abdominal wall into the body cavity and removing the flowing gas stream from the body cavity through the abdominal wall.5. A method as in claim 4 , wherein introducing and removing comprise positioning an inlet conduit and an outlet conduit through the abdominal wall claim 4 , wherein the flowing gas stream is introduced through the inlet conduit and flows out through the outlet conduit.6. A method as in claim 5 , wherein the inlet conduit is separate from the outlet conduit and is introduced through an opposed location on the abdominal wall.7. A method as in claim 5 , wherein the inlet conduit and outlet conduit are combined in a single structure which is introduced through a single penetration in the abdominal wall.8. A method as in claim 1 , wherein passing comprises exposing the flowing gas stream to the patient's skin.9. A method as in claim 8 , wherein the skin comprises skin over a torso of the patient.10. A method as in claim 9 , wherein the flowing gas stream is directed beneath a jacket structure which covers at least a portion ...

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Номер записи: 27
11-04-2013 дата публикации

Endovascular Cooling Catheter System which Employs Phase-Changing Heat Exchange Media

Номер: US20130090708A1
Автор: Dabrowiak Jeremy Thomas, Faller Frederick
Принадлежит: ZOLL CIRCULATION INC.

Devices and methods for cooling all or part of the body of a human or animal subject by inserting a heat exchange catheter into the subject's body and infusing into or through the catheter a heat exchange medium that contains liquid phase matter and frozen solid phase matter, wherein at least some of the solid phase matter melts while in the catheter. 1. A system comprising:a heat exchange catheter or other body cooling device that is insertable into or positionable in contact with the body of a human or animal subject, said catheter or other body cooling device having an inlet, an outlet and at least one lumen through which heat exchange medium may be circulated;a source of a heat exchange medium that comprises liquid phase matter and solid phase matter, wherein the solid phase matter has a melting point not higher than about 37 degrees C.; anda pump or pressurization apparatus for circulating the heat exchange medium through the catheter while the catheter is inserted in the body of a human or animal subject;wherein at least some of the solid phase matter melts thereby removing heat from the heat exchange medium.2. A system according to wherein the apparatus for delivering heat exchange medium comprises a pump or pressurization device connectable to the source of heat exchange medium.3. A system according to wherein the pump or pressurization device is connected to a vessel that contains a quantity of the heat exchange medium.4. A system according to wherein the heat exchange medium comprises a slurry.5. A system according to wherein the heat exchange medium is sterile.6. A system according to wherein the heat exchange medium is selected from the group consisting of:slurries comprising partially frozen saline solution;slurries comprising partially frozen 0.9% aqueous NaCl solution;7. A system according to wherein the heat exchange medium contains from about 18% to about 50% solid phase matter.8. A system according to wherein the source of heat exchange medium ...

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Номер записи: 28
11-04-2013 дата публикации

Method and apparatus for regional and whole body temperature modification

Номер: US20130090709A1
Автор: Alex T. Roth, Nicole Denise Bloom, Timothy R. Machold, Wade A. Keller
Принадлежит: Zoll Circulation Inc

Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette of any one of several disclosed variations is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within one of various described re-usable control units. The control units include a heater/cooler device, a user input device, and a processor connected to receive input from various sensors around the body and the system. The heater/cooler device may be thermoelectric to enable both heating and 15 ″ cooling based on polarity. A temperature control scheme for ramping the body temperature up or down without overshoot is provided. The disposable heat exchange cassettes may include an integral pump head that engages with a pump drive mechanism within the re-usable control unit. More than one control unit may be provided to receive the same heat exchange cassette so that, for example, a large capacity control unit can be used initially, and a smaller, battery-powered unit can be substituted once the patient reaches the desired target temperature.

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Номер записи: 29
11-04-2013 дата публикации

ALLEVIATIVE PILLOW

Номер: US20130090710A1
Автор: Rimoli Claudia
Принадлежит:

A back alleviative pillow uses hot and cold packs combined with memory foam in a pillow to provide comfort and alleviation from pain to an operator. The pillow includes a plurality of adjustable straps such that the pillow may be positioned at a desired location on the operator's body. The straps may secure the pillow to the operator, to a chair back, or other structure proximal to the desired point of contact on an operator's body. 1. An alleviative pillow comprising:a pillow having one or more pockets;one or more hot/cold packs capable of being placed within the one or more pockets;a backpack having two or more attachment straps and an interior compartment into which the pillow may be placed; and,one or more multifunctional straps removably attachable to the two or more attachments straps.2. The alleviative pillow of wherein the pillow has two pockets on opposite sides of the pillow and two hot/cold packs.3. The alleviative pillow of wherein the backpack has four attachment straps.4. The alleviative pillow of wherein the cavity of the backpack may be sealed by a zipper.5. The alleviative pillow of wherein the one or more multifunctional straps comprise three multifunctional straps each having an adjustable length.6. The alleviative pillow of wherein the backpack is rectangular and the two or more attachment straps comprise four attachment straps claim 2 , one on each of the corners of the backpack;wherein the one or more multifunctional straps comprise three multifunctional straps each having an adjustable length; and,wherein the multifunctional straps are attachable to the four attachment straps by means of snap hooks.7. An alleviative pillow comprising:a pillow having one or more pockets;one or more hot/cold packs capable of being placed within the one or more pockets;two or more attachment straps; and,one or more multifunctional straps removably attachable to the two or more attachments straps.8. The alleviative pillow of wherein the pillow has two pockets on ...

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Номер записи: 30
25-04-2013 дата публикации

Methods and Devices for Manipulating the Thermoregulatory Status of a Mammal

Номер: US20130102933A1
Автор: Grahn Dennis A., Heller H. Craig
Принадлежит: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Methods and devices for manipulating the thermoregulatory status of a mammal are provided. In the subject methods, thermal energy is transferred between the environment and both of the thoracic/abdominal core body and head of the mammal. In general, thermal energy transfer between thoracic/abdominal core body and the environment occurs under negative pressure conditions. The subject methods and devices can be used to increase the thoracic/abdominal core body temperature of a mammal, in which case thermal energy is introduced into the thoracic/abdominal core body of the mammal and removed from the head of the mammal or cold is merely applied thereto. The subject methods and devices can also be used to reduce the thoracic/abdominal core body temperature of a mammal, in which case thermal energy is removed from the thoracic/abdominal core body of the mammal and introduced into the head of the mammal or heat is merely applied thereto. 138-. (canceled)39. A device for transferring energy with a portion of a mammal , the device comprising:(a) a sealable enclosure for enclosing a portion of the mammal;(b) a negative pressure production component configured to produce negative pressure conditions in the sealable enclosure; and(c) an energy transfer element for transferring energy with the portion of the mammal when present in the sealable enclosure.40. The device according to claim 39 , wherein the portion of the mammal is a limb or portion thereof.41. The device according to claim 40 , wherein the limb is selected from the group consisting of an arm and a leg.42. The device according to claim 39 , where the device is configured to extract thermal energy from the core body a mammal.43. The device according to claim 39 , where the device is configured to introduce thermal energy into the core body a mammal.44. The device according to claim 39 , wherein the device comprises a component configured to transfer energy with the head of a mammal.45. The device according to claim ...

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Номер записи: 31
25-04-2013 дата публикации

Methods and Devices for Prevention of Hypothermia in a Mammal During Prolonged Exposure to Extreme Cold

Номер: US20130103128A1
Автор: Grahn Dennis A., Heller H. Craig
Принадлежит: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Methods and devices for preventing a change in the core body temperature of a mammal under cold conditions are provided. In the subject methods, a requirement for thermal energy input in said mammal is first detected. In response to the detection of this requirement for thermal energy input, a surface of a portion of the mammal is contacted with a warm temperature medium under negative pressure conditions for a period of time sufficient to introduce thermal energy into the core body of the mammal. The subject devices include at least a means for detecting a requirement for thermal energy input and a means for contacting a surface of the mammal with a warm temperature medium under negative pressure conditions. The subject methods and devices find use in a variety of applications, and are particularly suited for use in maintaining the core body temperature of a mammal substantially constant under cold conditions for an extended period of time. 1. A method for preventing a change in the core body temperature of a mammal under cold conditions , said method comprising:(a) detecting a requirement for thermal energy input in said mammal; and(b) contacting a surface of a portion of said mammal in response to the presence of said requirement with a warm temperature medium under negative pressure conditions for a period of time sufficient to introduce thermal energy into the core body of said mammal;whereby the core body temperature of said mammal is prevented from changing under said cold conditions.2. The method according to claim 1 , wherein said requirement is detected by detecting the presence of a thermoregulatory error in said mammal.3. The method according to claim 1 , wherein said thermoregulatory error is detected by detecting the presence of vasoconstriction in said mammal.4. The method according to claim 1 , wherein said method further comprises enclosing said portion of said mammal in a sealed enclosure to produce an enclosed portion of said mammal.5. The method ...

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Номер записи: 32
09-05-2013 дата публикации

MONITORING THE COOLING OF SUBCUTANEOUS LIPID-RICH CELLS, SUCH AS THE COOLING OF ADIPOSE TISSUE

Номер: US20130116758A1
Автор: Hinton Corydon A., Levinson Mitchell E., Rosen Jesse N., Springer Kevin S.
Принадлежит: Zeltiq Aesthetics, Inc.

A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event. 120.-. (canceled)21. A non-invasive treatment system for transdermally removing heat from subcutaneous lipid-rich cells of a subject , comprising:a transdermal treatment device configured to contact an area of skin of a subject and to remove heat from subcutaneous lipid-rich cells of the subject to affect the subcutaneous lipid-rich cells; anda controlling device that modifies operation of the non-invasive treatment system in response to an increase in power demand of one or more components of the non-invasive treatment system, wherein the increase in power demand is caused, at least in part, by at least partial freezing of the subject's skin.22. The non-invasive treatment system of claim 21 , further comprising a temperature monitoring device including a plurality of temperature sensors configured to detect a temperature of at least one of the subject's skin claim 21 , a portion of the transdermal treatment device claim 21 , and/or a protection device between the subject and the transdermal treatment device.23. The non-invasive treatment system of claim 21 , further comprising a temperature monitoring device that includes a first sensor and a second sensor spaced apart from the first sensor claim 21 , wherein the controlling device determines heat flux based on output from the first and second sensors and compares the heat flux to a reference heat flux.24. The non-invasive treatment system of wherein the transdermal treatment ...

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Номер записи: 33
09-05-2013 дата публикации

Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile

Номер: US20130116759A1
Автор: Jesse N. Rosen, Mitchell Levinson, William Pennybacker
Принадлежит: Zeltiq Aesthetics Inc

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

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Номер записи: 34
09-05-2013 дата публикации

COOLING MEDICAL PAD

Номер: US20130116760A1
Автор: Carson Gary A., Hoglund Michael R., Voorhees Marc E.
Принадлежит: Medivance Incorporated

A medical pad has multiple layers. A first layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the first layer. A second layer of the medical pad is interconnected to a second side of the first layer, opposite to the first side of the first layer. The second layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. The medical pad is operable for thermal exchange between the second thermal-exchange fluid and the patient. 1. A medical pad comprising:an upper containment sheet layer;an intermediate sheet layer having a plurality of depressions formed in a top surface defining a corresponding plurality of projections on a bottom surface; anda lower patient interface sheet layer having a top surface juxtaposed against the projections of the bottom surface of the intermediate sheet layer, wherein peripheries of the lower patient interface sheet layer and the intermediate sheet layer are connected such that spaces between the projections and the lower patient interface sheet layer collectively define a fluid circulation layer for containing a first thermal-exchange fluid circulatable therethrough; andwherein the upper containment sheet layer is disposed over the top surface of the intermediate sheet layer and peripheries of the upper containment sheet layer and the intermediate sheet layer are interconnected to define a fluid containment layer enclosing a second thermal-exchange fluid.2. The medical pad of claim 1 , wherein the upper containment sheet layer claim 1 , intermediate sheet layer and lower patient interface sheet layer comprise polymer materials and the peripheries are welded.3. The medical pad of claim 1 , wherein each of the plurality of depressions have a substantially equal depth and each of the plurality of projections has a substantially equal height.4. ...

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Номер записи: 35
09-05-2013 дата публикации

Rapid Cooling of Body and/or Brain by Irrigating with a Cooling Liquid

Номер: US20130116761A1
Автор: Thomas Kreck
Принадлежит: NeuroSave Inc

Methods and devices are disclosed for providing therapeutic hypothermia using irrigation of the aerodigestive tract with cooled liquids. The disclosed method provides much more rapid therapeutic cooling to lower temperatures than could previously be achieved, thereby improving clinical outcomes. Novel cooling liquids and cooling devices are disclosed for carrying out the method. An external turbulent flow of cooling liquid may also be applied to the exterior of the head to further promote heat exchange. Multiple embodiments of devices are disclosed for performing rapid induction and maintenance of therapeutic hypothermia either in a hospital setting or in the field so that hypothermic treatment can be quickly instituted before significant tissue damage occurs. Methods are also disclosed for targeting brain cooling by irrigating the upper airway/aerodigestive tract, and more generalized cooling by irrigating the esophagus and/or stomach.

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Номер записи: 36
16-05-2013 дата публикации

MEDICAL DEVICES

Номер: US20130123832A1
Автор: Chen John J., Hokanson John M., Weber Jan
Принадлежит: BOSTON SCIENTIFIC SCIMED, INC.

Medical systems and methods including balloons having nanotubes are disclosed. In some embodiments, a medical system includes an elongated shaft, and an expandable balloon carried by the shaft and including nanotubes. The medical system is capable of cooling the balloon to less than about 37° C. In some embodiments, a method includes providing a medical device having an elongated shaft, and an expandable balloon carried by the elongated shaft and including nanotubes; and cooling the balloon to less than about 37° C. 1. A balloon catheter , comprising:a first elongate shaft having a proximal end and a distal end;an expandable balloon affixed to the first elongate shaft adjacent the distal end thereof; anda first and second annular electrical contacts carried by the first elongate shaft, the electrical contacts positioned adjacent to the distal end of the first elongate shaft and within the expandable balloon;wherein the expandable balloon comprises a composite material including at least one polymer and a plurality of carbon nanotubes.2. The balloon catheter of claim 1 , wherein the first and second electrodes are configured to heat an inflation fluid disposed within the expandable balloon.3. The balloon catheter of claim 1 , wherein at least some of the plurality of carbon nanotubes extend from an inner surface of the expandable balloon to an outer surface of the expandable balloon.4. The balloon catheter of claim 1 , wherein the composite material has a thermal conductivity in the range of 70 percent to 125 percent higher than the thermal conductivity of the at least one polymer.5. The balloon catheter of claim 1 , further comprising at least one fiber having a proximal end and a distal end claim 1 , the at least one fiber extending along an outer surface of the expandable balloon.6. The balloon catheter of claim 5 , wherein the at least one fiber extends longitudinally along the outer surface of the expandable balloon.7. The balloon catheter of claim 5 , wherein ...

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Номер записи: 37
16-05-2013 дата публикации

HOT TIP LASER GENERATED VAPOR VEIN THERAPY DEVICE

Номер: US20130123888A1
Автор: Cheng Chun-Chih, Glaze Grant Michael, Jackson Jerome, Samson Wilfred J, Tartaglia Joseph M., Trebotich Steven H.
Принадлежит:

Methods and apparatus for generating vapor within a catheter are provided which may include any number of features. One feature is generating vapor with a fiber optic, laser fiber optic, or fiber optic bundle within a catheter. Another feature is sensing a temperature of the fiber optic, and adjusting the power delivered to the electrode array to fully generate vapor within the catheter. Another feature is delivering the vapor to a vein of a patient for vein reduction therapy. 1. A method for generating steam within a catheter , comprising:delivering a fluid to a vapor generation chamber;delivering power to a fiber optic disposed on or in the vapor generation chamber;sensing a signal from the fiber optic;adjusting the power delivered to the fiber optic based on the sensed signal to fully generate vapor in the vapor generation chamber.2. The method of wherein the signal is a fiber optic temperature.3. The method of wherein the power delivered is decreased as the sensed fiber optic temperature increases.4. The method of wherein the signal is a fluid flow rate.5. The method of wherein the signal is a steam temperature.6. The method of wherein the fluid is delivered at a constant flow rate.7. The method of wherein the fluid is delivered at a time varying rate.8. The method of wherein the fluid is delivered at a rate dependent upon the diameter of a vessel or organ being treated.9. The method of further comprising delivering vapor to a patient.10. The method of wherein the vapor is delivered to a vein of a patient.11. The method of wherein the power is adjusted automatically by a controller.12. The method of wherein the fiber optic comprises a laser fiber optic.13. The method of wherein the fiber optic comprises a fiber optic bundle.14. A vapor generating device claim 1 , comprising;a vapor generation chamber, the vapor generation chamber having a laser fiber optic disposed therein;a fluid reservoir coupled to the vapor generation chamber;a laser generator coupled to the ...

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Номер записи: 38
16-05-2013 дата публикации

Apparatus for Preventing Motion Sickness and Related Method

Номер: US20130123889A1
Автор: Hildemann Gunnar H., Katz Jay W.
Принадлежит:

The invention is directed toward a method of reducing motion sickness comprising the steps of introducing cooled gas into a user's ear canal to reduce the temperature of the user's tympanic membrane and vestibular system. The gas is circulated in the user's inner ear, and then exhausted to the atmosphere. The cooled gas induces nystagmus in the user, promotes vestibular desensitization and resistance to motion sickness. The apparatus contemplated for the prevention of motion sickness has an earpiece having a conduit that dispenses cooled gas into the user's ear canal. Gas is provided by a gas source connected to the earpiece with flexible tubing. 1. An apparatus for the prevention of motion sickness comprising:a gas supply;a conduit defining a first opening attachable to the gas supply and a second opening disposed proximate a user's ear canal to allow a gas introduced into the conduit from the gas supply to flow into the user's ear canal and cool a user's tympanic membrane.2. The apparatus for the prevention of motion sickness of further comprising an earpiece sized and dimensioned to engage a user's outer ear claim 1 , wherein the conduit passes through the earpiece claim 1 , wherein the second opening is disposed proximate the user's ear canal and the first opening is disposed proximate the user's outer ear.3. The apparatus for the prevention of motion sickness of further comprising an earpiece sized and dimensioned to engage a user's outer ear claim 1 , the earpiece having a protrusion that projects proximate the user's ear canal claim 1 , wherein the conduit passes through the protrusion claim 1 , wherein the second opening is disposed proximate a distal end of the protrusion and the first opening is proximate the user's outer ear.4. The apparatus for the prevention of motion sickness of further comprising an exhaust port defined by the earpiece that defines an exit route for the gas introduced into the user's ear canal for reducing uncomfortable pressure ...

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Номер записи: 39
16-05-2013 дата публикации

Therapeutic Cooling Devices

Номер: US20130123890A1
Автор: Jeffrey W. Latham
Принадлежит: TraumaTec Inc

A thermal regulatory system to reduce swelling caused by trauma to a variety of tissues and limbs is provided. One or more substantially flexible, at least partially thermally conductive housing containing optionally activatable thermal regulatory medium may be coupled with one or more applicator, such as a splint, that is adapted to apply the medium housing to the tissue. Methods of therapeutically regulating tissue temperature are also provided.

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Номер записи: 40
23-05-2013 дата публикации

Cool fat burner

Номер: US20130131764A1
Автор: P. Eric Grove
Принадлежит: Individual

An ice harness for cooling brown adipose tissue. The ice harness includes a front section, wherein the front section is configured to be placed on a user's chest. The ice harness also includes a rear section, wherein the rear section is configured to be placed on the user's upper back. The ice harness further includes a first cold-gel pack, wherein the first cold-gel pack is attached to the front section. The ice harness additionally includes a second cold-gel pack, wherein the second cold-gel pack is attached to the rear section.

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Номер записи: 41
06-06-2013 дата публикации

Renal neuromodulation methods and devices for treatment of polycystic kidney disease

Номер: US20130144251A1
Автор: Paul A. SOBOTKA
Принадлежит: Medtronic Ardian Luxembourg SARL

Methods for treating polycystic kidney disease with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a renal artery of a kidney of a patient. One or more measurable physiological parameter corresponding to the polycystic kidney disease can thereby be reduced. Moreover, central sympathetic drive in the patient can be reduced in a manner that treats the patient for the polycystic kidney disease. Renal sympathetic nerve activity can be modulated along the afferent and/or efferent pathway. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a neuromodulation assembly, e.g., a neuromodulation assembly configured to cryotherapeutically cool the renal nerve or to deliver an energy field to the renal nerve.

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Номер записи: 42
20-06-2013 дата публикации

METHODS FOR THERMALLY-INDUCED RENAL NEUROMODULATION

Номер: US20130158442A1
Автор: Clark Benjamin J., Demarais Denise, Gelfand Mark, Levin Howard R., Thai Erik, Zadno Nicolas
Принадлежит: Ardian, Inc.

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. 1. A method of treating a human patient diagnosed with a cardio-renal disease or disorder , the method comprising:intravascularly delivering a device to a vicinity of a neural fiber associated with renal function of the patient; andthermally inhibiting neural communication along the neural fiber with the device.2. The method of wherein thermally inhibiting neural communication along the neural fiber with the device comprises thermally inhibiting afferent neural communication along the neural fiber with the device.3. The method of wherein thermally inhibiting neural communication along the neural fiber with the device comprises thermally inhibiting efferent neural communication along the neural fiber with the device.4. The method of wherein intravascularly delivering a device to a vicinity of a neural fiber associated with renal function comprises intravascularly delivering the device via a renal blood vessel to a position proximate to the neural fiber.5. The method of wherein intravascularly delivering the device via a blood vessel to a position proximate to the neural fiber comprises intravascularly positioning the device in contact with a wall of the blood vessel proximate to the neural fiber.6. The method of wherein thermally inhibiting neural communication along the neural fiber with the device ...

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Номер записи: 43
20-06-2013 дата публикации

INDWELLING HEAT EXCHANGE CATHETER AND METHOD OF USING SAME

Номер: US20130158480A1
Автор: Evans Scott M., Gobin Yves Pierre, Jones Mike L., Noda Wayne A., Walker Blair D., Worthen William J.
Принадлежит:

A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system. 163-. (canceled)64. A heat exchange catheter comprising:at least one lumen configured for fluid communication with at least first and second heat exchange elements for circulating heat exchange fluid through the heat exchange elements to exchange heat with blood of a patient when at least a portion of the catheter is positioned in a bloodstream of the patient without the heat exchange fluid entering the bloodstream of a patient; whereineach of the first and second heat exchange elements are externally fluted along at least a respective segment thereof, wherein body fluid outward of a heat exchange element cannot flow to a long axis defined by a fluted configuration of the heat exchange element;wherein the first and second heat exchange elements are separated from each other by a flex region that is not externally fluted in a spiral configuration on a segment thereof.65. The catheter of claim 64 , wherein the heat exchange elements are axially arranged relative to each other.66. The catheter of claim 64 , wherein the catheter is provided with distal metal structure.67. The catheter of claim 65 , wherein the catheter is provided with distal metal structure.68. The catheter of claim 64 , comprising an anti-thrombogenic coating on at least a portion of the catheter.69. Apparatus comprising:at least one heat ...

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Номер записи: 44
20-06-2013 дата публикации

Pain management system

Номер: US20130158635A1
Автор: Charles Federico, Gregory Federico, Matthew Federico
Принадлежит: CMG HEALTHCARE LLC

A pain management system that includes a support undergarment with a pouch configured to removeably secure a therapy pack, wherein the support undergarment comprises an anti-microbial material and at least one moisture barrier. The system further includes a therapy pack configured to form into a contoured design.

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Номер записи: 45
27-06-2013 дата публикации

METHODS FOR THERMALLY-INDUCED RENAL NEUROMODULATION

Номер: US20130165822A1
Автор: Clark Benjamin J., Demarais Denise, Gelfand Mark, Levin Howard R., Thai Erik, Zadno Nicolas
Принадлежит: Ardian, Inc.

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. 1. A method for thermally-induced neuromodulation of a human patient , the method comprising:intravascularly delivering a device to a vicinity of a neural fiber that contributes to renal function of the patient; andthermally inducing modulation of a function of the neural fiber with the device.2. The method of wherein intravascularly delivering a device to a vicinity of a neural fiber that contributes to renal function comprises intravascularly delivering the device via a renal blood vessel to a position proximate the neural fiber.3. The method of wherein intravascularly delivering a device to a vicinity of a neural fiber that contributes to renal function comprises:intravascularly delivering the device in a low profile delivery configuration to a position within a renal blood vessel of the patient and proximate the neural fiber; andtransforming the device from the delivery configuration to a deployed configuration within the renal blood vessel before thermally inducing modulation.4. The method of claim 3 , further comprising:transforming the device from the deployed configuration to the low profile configuration after thermally inducing modulation of a function of the neural fiber; andremoving the device from the patient.5. The method of wherein the device comprises an expandable wire basket carrying ...

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Номер записи: 46
11-07-2013 дата публикации

Heat Exchange Catheters with Bi-Directional Fluid Flow and Their Methods of Manufacture and Use

Номер: US20130178923A1
Автор: Dabrowiak Jeremy Thomas
Принадлежит: ZOLL CIRCULATION, INC.

Closed loop heat exchange catheters having bi-directional flow heat exchange regions and their methods of manufacture and use. The heat exchange region may be formed of expandable or non-expandable tubular conduit(s) that are configured in a series of loops or coiled configuration defining a supply flow path and a return flow path through which heat exchange medium is circulated. The individual loops of convolutions of the coiled configuration may be the same or different size. In some embodiments, the tubular conduit(s) may be passed through generally transverse bore holes formed in a catheter shaft so that the loops or convolutions of protrude from the catheter shaft. 1. A catheter device comprising:an elongate catheter body; anda heat exchange region having a proximal end and a distal end;said heat exchange region comprising a first flow path through which heat exchange fluid flows toward the distal end and a second flow path through which heat exchange fluid flows toward the proximal end.2. A catheter device according to wherein the heat exchanger comprises a tube through which heat exchange fluid flows claim 1 , a first segment of said tube forming the first flow path and a second segment of said tube forming the second.3. A catheter device according to wherein the catheter body has an inflow lumen and an outflow lumen and the tube has a first end and a second end and wherein:the first end of the tube is connected to the inflow lumen;the first segment of the tube forms the first flow path;the second segment of the tube forms the second flow path; andthe second end of the tube is connected to the outflow lumen.4. A catheter device according to wherein the tube has a wall thickness that is thinner than the wall thickness of the catheter body.5. A catheter device according to wherein a series of transverse bores are formed in the catheter body and the tube is threaded through said bores such that loops of said tube reside outside of the catheter body.6. A catheter ...

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Номер записи: 47
18-07-2013 дата публикации

APPARATUS FOR PERFORMING HEAT TREATMENT

Номер: US20130184791A1
Автор: Wallsten Hans I.
Принадлежит: PNN MEDICAL SA

The present invention relates to an apparatus for performing heat treatment of a bodily cavity in a mammal. The apparatus comprises a catheter intended for insertion into said bodily cavity, an inflatable balloon surrounding a distal end of said catheter in a liquid tight manner which balloon is adapted in use of said apparatus to be inflated and dilated in said bodily cavity, control means operatively connected to said balloon by at least one oscillation lumen and being provided with an oscillation assembly adapted to drive a heat transmitting fluid within said apparatus, and heating means adapted to heat said heat transmitting fluid. Said control means are adapted to control pressure and temperature of said heat transmitting fluid. The heating means have a heat emitting portion and a heat receiving portion which is use of the apparatus are positioned in thermal contact with each other, and which are separable from each other. 1. Apparatus for performing heat treatment of a bodily cavity in a mammal , comprising a catheter intended for insertion into said bodily cavity , an inflatable balloon surrounding a distal end of said catheter in a liquid tight manner which balloon is adapted in use of said apparatus to be inflated and dilated in said bodily cavity , control means operatively connected to said balloon by at least one oscillation lumen and being provided with an oscillation assembly adapted to drive a heat transmitting fluid within said apparatus , and heating means adapted to heat said heat transmitting fluid , said control means being adapted to control pressure and temperature of said heat transmitting fluid , wherein said heating means have a heat emitting portion and a heat receiving portion which in use of the apparatus are positioned in thermal contact with each other , and which are separable from each other.2. Apparatus according to claim 1 , wherein said apparatus is separable into a reusable unit and a disposable unit claim 1 , said disposable unit ...

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Номер записи: 48
25-07-2013 дата публикации

Methods and devices for selective disruption of visceral fat by controlled cooling

Номер: US20130190744A1
Автор: Joshua Tam, Matthew M. Avram, Richard R. Anderson
Принадлежит: General Hospital Corp

The present invention provides methods and apparatus for use in the selective disruption of visceral fat tissue by controlled cooling.

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Номер записи: 49
01-08-2013 дата публикации

Selective accumulation of energy with or without knowledge of tissue topography

Номер: US20130197614A1
Автор: Arthur G. Blanck, Linas Kunstmanas, Rolfe Tyson Gustus
Принадлежит: Vessix Vascular Inc

Medical devices and methods for making and using medical devices are disclosed. An example method may include a method for heating a body tissue region adjacent to a body lumen. The method may include positioning an energy delivery portion of a catheter within the lumen and engaging the body lumen with the energy delivery portion. Engaging the body lumen may complete a plurality of circuits. The method may also include determining a pulse characteristic in response to a thermal property of a first tissue type and applying controlled pulsed electrical energy with the pulse characteristic from the energy delivery portion through the plurality of circuits.

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Номер записи: 50
08-08-2013 дата публикации

BODY COOL HARNESS

Номер: US20130204332A1
Автор: Amalfi Michael
Принадлежит: Body Cool LLC

A body cool harness is disclosed. The body cool harness may have a body portion for overlaying the back region of a person, a first wrap-around portion, and at least one cooling device. 1. A body cool harness having a body portion for overlaying the back region of a person , a first wrap-around portion , a second wrap-around portion , and at least one cooling device , wherein the first wrap-around portion and the second wrap-around portion fasten to one another with a strap.2. The body cool harness of claim 1 , further comprising a third wrap-around potion claim 1 , and a fourth wrap-around portion claim 1 , wherein the third wrap-around portion and the fourth wrap-around portion are configured to fasten around the legs of a person for overlaying the groin region of a person.3. The body cool harness of claim 2 , wherein the first claim 2 , second claim 2 , third claim 2 , and fourth wrap around portions each include a cooling device.4. The body cool harness of claim 3 , wherein the body portion comprises an insulating fabric claim 3 , a breathable fabric claim 3 , a base fabric claim 3 , and a stretchable fabric.5. The body cool harness of claim 4 , wherein the base fabric includes at least one cut out region for housing the cooling device.6. The body cool harness of claim 5 , wherein the cooling device is disposed between the insulating fabric and the breathable fabric.7. The body cool harness of wherein the stretchable fabric is disposed between base fabric.8. The body cool harness of claim 7 , wherein the cooling device has an impermeable bag having a selectively breakable barrier therein claim 7 , thereby dividing the bag into a first package and a second package.9. The body cool harness of claim 8 , wherein the first package contains water.10. The body cool harness of claim 9 , wherein the second package contains a reactant claim 9 , such as ammonium nitrate.11. The body cool harness of claim 1 , wherein the cooling device has a selectively breakable bag inside ...

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Номер записи: 51
15-08-2013 дата публикации

Therapeutic Brain Cooling System and Spinal Cord Cooling System

Номер: US20130211484A1
Автор: Rozental Renato
Принадлежит:

This disclosure relates to a brain cooling and spinal cord cooling system, device or mechanism for use in military helmets, and in an adapted format in non-military helmets. The system is comprised of an inflatable pad, or a set of interconnected pads, attached to the interior surface of the helmet, together with a series of valves that allow cooling gases to be delivered from a high pressure canister. The use of different cooling gases permits the achievement and maintenance of cooling of the brain for 24 to 96 hours at a mild (36° C.) or moderate (33° C.-35° C.) brain hypothermia, which is 1.5° C.-4.5° C. below the core temperature. 1. A helmet for protection of a user's brain , said helmet comprising:a. a helmet body;b. one or more inflatable pads attached to said helmet body;c. one or more bi-directional pressure-sensitive valves;d. a temperature-sensitive probe capable of determining the user's brain temperature; ande. at least one coolant-containing canister capable of inflating said inflatable pads and cooling the user's brain; wherein the coolant is capable of providing a cooling rate to the brain ranging from about 0.1° C. to about 0.5° C./hour.2. The helmet of claim 1 , wherein the helmet is capable of lowering the user's brain temperature to a mean temperature ranging from about 33° C. to about 36° C.3. The helmet of claim 2 , wherein the helmet is capable of maintaining the temperature of the user's brain within the range of about 33° C. to about 36° C. for about 24 hours to about 96 hours.4. The helmet of claim 3 , wherein the helmet is capable of maintaining the temperature of the user's brain within the range of about 33° C. to about 36° C. for about 48 hours to about 72 hours.5. The helmet of claim 4 , wherein the helmet is capable of maintaining the temperature of the user's brain within the range of about 33° C. to about 36° C. for about 48 hours to about 56 hours.6. The helmet of claim 1 , wherein the helmet is capable of cooling the user's brain ...

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Номер записи: 52
22-08-2013 дата публикации

Pain Management Using Cryogenic Remodeling

Номер: US20130218148A1
Автор: Keith Burger, Lisa Elkins, Ronald Williams
Принадлежит: MyoScience Inc

Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated.

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Номер записи: 53
29-08-2013 дата публикации

Hypothermia Devices and Methods

Номер: US20130226077A1
Автор: Daniel Rogers Burnett, Gregory W. HALL
Принадлежит: Velomedix Inc

A method of providing hypothermia to a patient including the steps of inserting a fluid delivery member into a peritoneal cavity of the patient; delivering hypothermia fluid from a fluid source into the peritoneal cavity through the delivery member; and limiting fluid pressure within the peritoneal cavity without providing feedback control to the fluid source. The invention also provides an apparatus for practicing the method.

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Номер записи: 54
12-09-2013 дата публикации

Cryotreatment device and method

Номер: US20130238064A1
Автор: Daniel M. Lafontaine
Принадлежит: Boston Scientific Scimed Inc

Devices and methods for cooling vessel walls to inhibit restenosis in conjunction with medical procedures such as coronary artery angioplasty. One catheter device includes a distal tube region having coolant delivery holes radially and longitudinally distributed along the distal region. In some devices, holes spray coolant directly onto the vessel walls. In other embodiments, a balloon or envelope is interposed between the coolant and the vessel walls and the coolant returned out of the catheter through a coolant return lumen. Some direct spray devices include an occlusion device to restrict blood flow past the region being cooled. Pressure, temperature, and ultrasonic probes are included in some cooling catheters. Some cooling catheters are coiled perfusion catheters supporting longer cooling periods by allowing perfusing blood flow simultaneously with vessel wall cooling.

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Номер записи: 55
19-09-2013 дата публикации

Vaginal remodeling device and method

Номер: US20130245728A1
Автор: Donald I. GALEN, Ian F. Smith, Jerome Jackson, Russell MEIROSE, Srihari Yamanoor, Steven Marc Lopez
Принадлежит: Viveve Inc

This invention provides devices and methods for remodeling the female genital tissue, the device comprising a treatment tip, wherein the distal end of the treatment tip is conical, spherical, hemispherical, oval or circular in shape. The device further comprises one or more energy delivery elements for simultaneous cooling of the vaginal epithelium and transmission of energy for heating the tissues underneath the epithelium. In one embodiment, said device may further comprise one or more of the following: one or more temperature sensors for measuring the temperature at or below the epithelium; one or more directional sensors mounted on the hand piece or treatment tip; and one or more depth markers to show the depth of penetration of the treatment tip into the vagina. In another embodiment, this invention provides a device having a finger holder with electrodes for remodeling the female genital tissue.

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Номер записи: 56
03-10-2013 дата публикации

COLD THERAPY DEVICE

Номер: US20130261712A1
Автор: EBEL JAMES PATRICK, FRANCO MARLE, LOOMIS ERIK DOUGLAS
Принадлежит: PFIZER INC

The present invention is directed to a device for absorbing heat from a body. More particularly, the invention pertains to an improved device which utilizes a gel material comprising liquids and solids to absorb, over an extended period of time, heat from a body. The present invention also includes methods of providing cold therapy treatment to a user 1. A multi-use cold pack device comprising:a. an attachment wrap having a highly adjustable fastening zone;b. a body-side insulation layer;c. a clothing-side insulation layer; andd. a multi-cell gel composition, wherein said gel composition does not include an antifreeze component.2. A multi-use cold pack device comprising:a. an attachment wrap comprising a Z-configuration and having a highly adjustable fastening zone;b. a body-side insulation layer;c. a clothing-side insulation layer; andd. a multi-cell gel composition, wherein said gel composition does not include an antifreeze component.3. A multi-use cold pack device comprising:a. an attachment wrap comprising a Z-configuration and having a highly adjustable fastening zone, and further comprising a corrugated material;b. a body-side insulation layer;c. a clothing-side insulation layer; andd. a multi-cell gel composition, wherein said gel composition does not include an antifreeze component.4. A multi-use cold pack device comprising:a. an attachment wrap comprising a corrugated material and having a highly adjustable fastening zone;b. a body-side insulation layer;c. a clothing-side insulation layer; andd. a multi-cell gel composition, wherein said gel composition does not include an antifreeze component.5. A multi-use cold pack device according to any one of to , wherein the thickness of said body-side insulation layer is thinner than the thickness of said clothing-side insulation layer.6. A multi-use cold pack device according to any one of to , wherein said body-side insulation layer has an R-value of 0.001 m-K/W to 0.01 m-K/W.7. A multi-use cold pack device ...

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Номер записи: 57
10-10-2013 дата публикации

DUAL PURPOSE ADHESIVE BANDAGE

Номер: US20130267925A1
Автор: Aybar López Héctor M., Dunshee Wayne K.
Принадлежит:

Dual purpose adhesive bandages comprise a backing, a pressure sensitive adhesive disposed on the backing, and an absorbent pad adhered to the backing. The absorbent pad is configured so as to form a pouch having at least one open end for releasably receiving a thermal pack. Thermal management kits comprise the dual purpose bandage and a thermal pack. 2. The adhesive bandage of wherein the absorbent pad is folded to form a tube.3. The adhesive bandage of wherein the absorbent pad is folded in a c-fold.4. The adhesive bandage of wherein the absorbent pad comprises cotton gauze laminated to netting.5. The adhesive bandage of wherein the absorbent pad comprises a nonwoven material.6. A thermal management kit comprising:(a) an adhesive bandage comprising a backing, a pressure sensitive adhesive disposed on the backing, and an absorbent pad adhered to the backing by the pressure sensitive adhesive, wherein the absorbent pad is configured so as to form a pouch having at least one open end for releasably receiving a thermal pack; and(b) a thermal pack comprising a flexible sealed envelope and a thermal agent within the envelope.7. The thermal management kit of wherein the thermal pack is a cold pack.8. The thermal management kid of or wherein the thermal agent is a gel.9. The thermal management kid of wherein the thermal agent is a thixotropic gel.10. The thermal management kit of wherein the thermal pack contains between about 3 g/inand about 5 g/inof thermal agent.11. The thermal management kit of wherein the thermal pack contains between about 3 g/inand about 4 g/inof thermal agent.12. The thermal management kit of wherein the thermal pack is from about 1 inch to about 2 inches wide and from about 1 inch to about 4 inches long.13. The thermal management kit of wherein the thermal pack is from about 1 inch to about 1.5 inches wide and from about 2 inches to about 4 inches long.14. The thermal management kit of wherein the thermal pack contains from about 10 grams to about ...

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Номер записи: 58
10-10-2013 дата публикации

Apparatus and Method of Treating a Vein with Heat Energy

Номер: US20130268036A1
Автор: Daniel Recinella, Joseph M. Tartaglia, Kimberly McCarthy, Lowell S. Kabnick, Sean Morris
Принадлежит: Veniti Inc

A method of delivering therapy to a vein. In one embodiment, the method includes the following steps: inserting a structural sheath into the vein, the structural sheath being configured to prevent collapse of the vein due to spasm or via the administration of tumescent anesthesia; advancing a vapor delivery shaft into the catheter sheath; positioning a vapor delivery tip of the vapor delivery shaft distally of the catheter sheath; and delivering vapor to the vein through the vapor delivery tip to, e.g., shrink the vein with the vapor. The invention also includes a vapor delivery catheter system adapted to perform the method.

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Номер записи: 59
07-11-2013 дата публикации

SURGICAL COOLING DEVICE

Номер: US20130296982A1
Автор: Canty Richard Dashan, Davila Luis Alberto, Feng Yusheng, Long Justin Alexander, Parekh Dipen J.
Принадлежит: Board of Regnets of the University of Texas

Surgical cooling may be implemented by various systems, processes, and techniques. In certain implementations, a surgical cooling device includes a shaft, a cooling assembly, and a mechanical control system. The shaft includes a pair of axial cooling channels extending through its interior. The cooling assembly includes a pair of arms pivotally attached to the shaft and a foldable thermal exchanger coupled to the pair of arms and fluidly coupled to the pair of axial cooling channels. The mechanical control system is adapted to unfold the cooling assembly from a closed position to an open position to allow a coolant to flow through a first of the pair of axial cooling channels, through one or more thermal exchange channels, and out a second of the pair of cooling channels. 1. A surgical cooling device comprising:a shaft having a pair of axial channels extending through the interior of the shaft;a cooling assembly comprising a pair of arms pivotally attached to the shaft and a foldable thermal exchanger coupled to the pair of arms and fluidly coupled to the pair of axial channels, the thermal exchanger comprising an inlet port, an outlet port, and one or more thermal exchange channels fluidly connecting the inlet port to the outlet port; anda mechanical control system for activating the pair of arms to unfold the thermal exchanger from a closed position to an open position to allow a coolant to flow through a first of the pair of axial cooling channels, through the one or more exchange channels, and out a second of the pair of axial cooling channels.2. A surgical cooling device comprising:a body comprising a handle, a shaft adjacent to the handle, a pair of shoulders adjacent to the shaft, and a pair of axial cooling channels extending through the interiors of the handle and the shaft, each of the pair of axial cooling channels having at least one inflow and one outflow port; anda cooling assembly comprising a pair of arms pivotally attached to the pair of shoulders, ...

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Номер записи: 60
07-11-2013 дата публикации

MULTIPLE LUMEN HEAT EXCHANGE CATHETERS

Номер: US20130296983A1
Автор: KELLER Wade A., Machold Timothy R.
Принадлежит:

Catheter devices and methods for intravascular heating and/or cooling of human or veterinary patients. The catheter devices generally comprise catheters having inflow and outflow lumens and at least one curvilinear balloon connected to the inflow and outflow lumens such that heat exchange fluid may be circulated through the balloon(s). The catheter is inserted into the vasculature and heated or cooled fluid is circulated through the balloon(s) to heat or cool blood flowing in heat-exchange proximity to the balloon(s), thereby effecting heating or cooling of all or a portion of the patient's body. 1. A method for controlling the temperature of at least a portion of the body of a human or animal subject , said method comprising the steps of: the heat exchange catheter comprises an elongate, flexible catheter having an inflow lumen and an outflow lumen and at least one heat exchanger having first and second ends, the inflow lumen of the catheter being connected to the first end of the heat exchanger and the outflow lumen being connected to second end of the heat exchanger such that heat exchange fluid may be circulated into the first end of the heat exchanger, through the heat exchanger and out of the second end of the heat exchanger; and', 'the controller receives i) a target temperature input and ii) a sensed subject body temperature input and causes heated or cooled fluid to circulate into the first end of the heat exchanger, through the heat exchanger and out of the second end of the heat exchanger, to warm or cool the sensed subject body temperature as needed to cause the sensed subject body temperature to be approximately the same as the target temperature;, 'A) obtaining a heat exchange catheter system that comprises a heat exchange catheter and a controller, whereinB) inserting the heat exchange catheter into the vasculature of the patent and positioning the heat exchanger within a blood vessel through which blood is flowing such that the heated or cooled fluid ...

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Номер записи: 61
07-11-2013 дата публикации

Automated Therapy System and Method

Номер: US20130296984A1
Автор: Burnett Daniel Rogers, HALL Gregory W., Hermanson Christopher, Rajguru Amit
Принадлежит:

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient. 1. A method of inducing and reversing therapeutic hypothermia in a patient , the method comprising:infusing a therapeutic agent from a catheter into a peritoneal cavity of the patient;monitoring a flow of the therapeutic agent through the catheter with a sensor to generate a sensor signal;providing the sensor signal to a controller; andadjusting infusion of the therapeutic agent from the catheter to the peritoneal cavity with the controller based on the sensor signal to induce or reverse therapeutic hypothermia in the patient without removing the therapeutic agent from the patient.2. The method of wherein the therapeutic agent is infused into the patient with a peritoneal catheter.3. The method of wherein the infusing step comprises a peritoneal lavage.4. The method of wherein the adjusting step is performed after the infusing step.5. The method of wherein the therapeutic agent comprises a chilled fluid.6. The method of wherein the sensor is positioned in the catheter.7. The method of wherein the sensor is separate from the catheter.8. A system configured to induce and reverse therapeutic hypothermia or hyperthermia in a patient claim 1 , the system comprising:a fluid source having a therapeutic agent;a peritoneal catheter coupled to the fluid source, the peritoneal catheter configured to infuse the therapeutic agent into ...

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Номер записи: 62
07-11-2013 дата публикации

INDWELLING HEAT EXCHANGE CATHETER AND METHOD OF USING SAME

Номер: US20130296985A1
Автор: Evans Scott M., Gobin Yves Pierre, Jones Mike L., Noda Wayne A., Walker Blair D., Worthen William J.
Принадлежит:

A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

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Номер записи: 63
07-11-2013 дата публикации

Therapeutic Cold Compress Apparatus and Method for Use

Номер: US20130296986A1
Автор: Alan Lynn Dukes
Принадлежит: Individual

Various embodiments are disclosed for applying a cool compression effect. One embodiment, among others, is an adjustable wrap configured as a sleeve with a variable peripheral size. The wrap comprises a first elongated layer comprising a liquid-absorbent sheet and a second elongated layer. The first elongated layer and the second elongated layer are substantially coextensive in size, and one of the first elongated layer and the second elongated layer is configured to be applied directly to a selected body part and provide a cold compression effect to the body part. The adjustable wrap further comprises a fastener coupled to one of the first elongated layer and the second elongated layer, the fastener comprising a first section and a second section for providing an adjustable peripheral size of the wrap.

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Номер записи: 64
14-11-2013 дата публикации

COMBINATION TREATMENTS

Номер: US20130304165A1
Автор: Rogers Lesco L.
Принадлежит: Scion Neuro Stim ,LLC

A method of treating a subject in need thereof, is carried out by (a) administering said subject a therapeutic intervention (e.g., an active agent) in a treatment effective amount; and concurrently (b) administering said subject caloric vestibular stimulation in a treatment effective amount, said caloric vestibular stimulation administered so as to enhance the efficacy of said active agent. In some embodiments, the caloric vestibular stimulation is administered as an actively controlled time varying waveform. 1. A method of treating a subject in need thereof , comprising:(a) administering said subject an active agent in a treatment effective amount; and concurrently(b) administering said subject caloric vestibular stimulation in a treatment effective amount, said caloric vestibular stimulation administered so as to enhance the efficacy of said active agent.2. The method of claim 1 , wherein said caloric vestibular stimulation is administered as an actively controlled time varying waveform.3. The method of claim 1 , wherein said active agent is selected from the group consisting of analgesics claim 1 , headache medications claim 1 , antidiabetic agents claim 1 , anti-epileptic agents claim 1 , antidepressive agents claim 1 , antipsychotic agents claim 1 , anxiolytic agents claim 1 , active agents for treating bipolar disorder claim 1 , mood stabilizer active agents claim 1 , anti-insomnia (including sedative hypnotic) active agents claim 1 , active agents for treating stroke claim 1 , active agents for treating substance abuse disorders claim 1 , dependence and withdrawal claim 1 , active agents for treating ADHD claim 1 , active agents for treating Alzheimer's disease claim 1 , active agents for treating Parkinson's disease and extrapyramidal symptoms claim 1 , active agents for treating neuropathic pain claim 1 , active agents for treating nociceptive pain claim 1 , active agents for treating obesity claim 1 , active agents for treating obesity associated disorders ...

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Номер записи: 65
14-11-2013 дата публикации

INHIBITION OF PLATELET ACTIVATION, AGGREGATION AND/OR ADHESION BY HYPOTHERMIA

Номер: US20130304166A1
Автор: Dae Michael W., KELLER Wade A., Machold Timothy R.
Принадлежит:

A method for treating acute coronary syndromes (i.e., unstable angina or non-Q-wave MI) or transient ischemic attacks in a human or animal patient by placing a heat exchange apparatus in the patient's vasculature and using that heat exchange apparatus to cool the patient to a temperature (e.g. 30-36 degrees C.) at which platelet inhibition (i.e., inhibition of platelet activation and/or aggregation and/or adhesion) occurs. Anti-shivering drugs or anesthesia may be administered to patients whose body temperature is cooled below that patient's shivering threshold (typically approximately 35.5 degrees C.). If it is determined that platelet inhibition is no longer desirable, such as when the patient is about to undergo a surgical or interventional procedure wherein bleeding could be problematic, the hypothermia-induced platelet inhibition may be rapidly reversed by using the intravascular heat exchange apparatus to re-warm the patient's body to normothermia or near normothermia. 1. A method for inhibiting platelet activation , aggregation or adhesion in a human or veterinary patient , said method comprising the steps of:(a) providing a catheter that is insertable into the patient's vasculature and has a heat exchanger for cooling the patient's blood;(b) inserting a distal portion of the catheter, including the heat exchanger, into the patient's vasculature; and,(c) using the heat exchanger to cool the patient's blood sufficiently to inhibit platelet activation, aggregation or adhesion.2. A method according to wherein the patient's blood is cooled to a temperature between approximately 30 degrees C. and approximately 36 degrees C.3. A method according to wherein the heat exchanger is present on less than the full length of the portion of the catheter that is inserted in the patient's vasculature.4. A method according to wherein it is desired to inhibit platelet activation claim 1 , aggregation or adhesion in the coronary vasculature and wherein the heat exchanger is ...

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Номер записи: 66
28-11-2013 дата публикации

APPARATUS AND METHODS FOR PRODUCING BRAIN ACTIVATION VIA THE VESTIBULAR SYSTEM WITH TIME-VARYING WAVEFORMS

Номер: US20130317576A1
Автор: Black Robert D., Rogers Lesco L., Smith Lanty L.
Принадлежит: Scion NeuroSlim LLC

A device for delivering caloric vestibular stimulation to an individual, includes: (a) an earpiece configured to be at least partially insertable into the ear canal of the individual for delivering said caloric vestibular stimulation; (b) a power supply operatively associated with said earpiece; and (c) a controller operatively associated with said power supply and said earpiece for configuring said caloric vestibular stimulation as at least a first and second time-varying waveform. Preferably, the waveforms are actively controlled waveforms. 1. A device for delivering caloric vestibular stimulation to an individual , comprising:(a) an earpiece configured to be at least partially insertable into the ear canal of the individual for delivering said caloric vestibular stimulation;(b) a power supply operatively associated with said earpiece; and(c) a controller operatively associated with said power supply and said earpiece for configuring said caloric vestibular stimulation as at least a first and second time-varying waveform.2. The device of claim 1 , further comprising(d) a thermoelectric device connected to said earpiece, wherein said earpiece is operatively associated with said controller through said thermoelectric device.3. The device of claim 2 , further comprising:(e) a temperature sensor thermally connected to said earpiece and operatively associated with said controller;and wherein said controller delivers said time-varying waveforms as actively controlled time varying waveforms responsive to said temperature sensor.4. The device of claim 1 , further comprising:(f) a heat sink operatively associated with said earpiece.5. The device of claim 1 , wherein said earpiece is comprised of metal.6. The device of claim 1 , wherein said at least a first and second time-varying waveform comprises from 3 to 10 sequential waveforms.7. The device of claim 1 , wherein each of said time varying waveforms comprises a ramped leading edge and/or a ramped trailing edge.8. The ...

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Номер записи: 67
12-12-2013 дата публикации

Devices for cooling the nasal cavity

Номер: US20130331915A1
Автор: Allan Rozenberg, James D. Savage, John K. Hoffman
Принадлежит: BeneChill Inc

A method for cerebral cooling is described using a cooling assembly, which includes first and second elongate tubular members adapted for insertion into a nasal cavity of a patient through the patient's nostrils. The elongate tubular members each have a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen. The cooling assembly also includes a manifold and a reservoir, which contains a pressurized fluid that includes a propellant having a boiling point less than 22° C. The elongate tubular members are inserted into the nasal cavity through the patient's nostrils and pressurized fluid is delivered onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and second elongate tubular members.

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Номер записи: 68
12-12-2013 дата публикации

SYSTEMS AND METHODS FOR INTRAVASCULAR COOLING

Номер: US20130331916A1
Автор: Lin Erwin, Pile-Spellman John
Принадлежит: HYBERNIA MEDICAL LLC

Methods and systems for infusing a cooled infusate to a target location in a patient are described. A temperature of the blood and infusate admixture upstream of the catheter as well as at other locations along the catheter may be monitored and a feedback system utilized to control the volume, temperature, and/or infusion rate of the infusate so as to achieve a predetermined temperature at the target location. Control may also be based on the patient's native vessel flow rate. The system may monitor or calculate hematocrit upstream of the catheter and adjust infusion so as to provide sufficient oxygenation of the blood and infusate admixture. The system may also monitor reflux of the infusate past a distal end of the catheter and reduce infusion upon the detection of reflux. 170-. (canceled)71. A method comprising:communicating with a source of an infusate; andcontrolling at least one of (a) a temperature of the infusate, (b) an infusion rate of the infusate through an insertion device, and (c) a volume of the infusate passing through the insertion device in a downstream direction, in accordance with a temperature of a blood and infusate mixture downstream relative to an infusate exit location of the insertion device while the insertion device is placed in a blood vessel of a patient with a downstream flow of blood for infusion of the infusate, and in accordance with at least one of (a) a temperature of the infusate at least one of at and adjacent the exit location, (b) a temperature upstream and adjacent the exit location, and (c) a core body temperature of the patient.72. The method according to claim 71 , further comprising:receiving signals from a plurality of temperature sensors, at least one of the temperature sensors is positioned downstream relative to the infusate exit location;measuring a temperature of the infusate and blood mixture by at least one of the temperature sensors; andmeasuring at least one of (a) a temperature of the infusate adjacent the exit ...

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Номер записи: 69
19-12-2013 дата публикации

Topical Patch For Pain Relief Using Cooling Agent

Номер: US20130337032A1
Автор: Jutaro Shudo
Принадлежит: Teikoku Pharma USA Inc

Topical patch preparations that contain an odorless physiological cooling agent, and methods for using the same are provided. The subject topical patch preparations are made up of an adhesive gel composition that is present on a support, where the adhesive gel composition includes the odorless physiological cooling agent, a water-soluble polymer gel, water and a water holding agent. In using the subject topical patch preparations, the topical patch preparations are applied to a skin surface of a subject and maintained at the site of application for a period of time sufficient for an effective amount of the an odorless physiological cooling agent to be administered to the subject. The subject invention finds use in a variety of applications.

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Номер записи: 70
19-12-2013 дата публикации

GASTRODUODENAL BALLOON TUBES AND METHODS FOR USE IN LOCALIZED HYPOTHERMIA

Номер: US20130338741A1
Автор: Singh Vijay P.
Принадлежит: Mayo Foundation for Medical Education and Research

Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer). 126-. (canceled)27. A gastroduodenal device comprising:a balloon catheter comprising a proximal end and a distal end;a gastric balloon attached to and located along the hollow balloon catheter between the proximal end and the distal end of the balloon catheter;a first duodenal balloon attached to and located along the balloon catheter between the gastric balloon and the distal end of the balloon catheter, wherein the first duodenal balloon is spaced from the gastric balloon along the balloon catheter by a first distance configured to place the first duodenal balloon in the duodenum of a patient distal from the ampulla of Vater of the patient when the gastric balloon is in the stomach of the patient; anda second duodenal balloon attached to and located along the balloon catheter between the gastric balloon and the first duodenal balloon, wherein the second duodenal balloon is spaced from the first duodenal balloon along the balloon catheter by a second distance, wherein the second distance is configured to place the second duodenal balloon in the duodenum proximal of the ampulla of Vater when the first duodenal balloon is distal from the ampulla of Vater in the duodenum and the gastric balloon is in the stomach of the patient;a first duodenal balloon lumen passing through the balloon catheter and in fluid communication with the first duodenal balloon, wherein the first duodenal balloon lumen is configured to deliver first duodenal balloon cooling fluid to the first duodenal balloon; anda second duodenal balloon lumen passing through the balloon catheter and in fluid communication with the second duodenal balloon, wherein the second duodenal balloon lumen is configured to deliver second duodenal balloon cooling fluid to the second duodenal balloon.28. The device of claim 27 , wherein the device further comprises a jejunal extension ...

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Номер записи: 71
02-01-2014 дата публикации

Devices and Systems for Stimulation of Tissues

Номер: US20140005759A1
Автор: Fahey Brian J., Machold Timothy, MALCHANO Zachary J., Tom Curtis
Принадлежит:

NMES systems and methods for stimulating muscle tissue, and in some embodiments deep muscle tissue. The impedance near the surface of the skin is controllably increased to increase the percentage of energy delivered to a subject that stimulates muscle tissue. 1. A method of stimulating muscle comprising:positioning a plurality of muscle stimulation electrodes on a patient proximate muscle to be stimulated;positioning a first thermal element associated with a first thermal source and a second thermal element associated with a second thermal source relative to a patient proximate the plurality of electrodes;activating the first thermal source to cause a temperature change in the patient's tissue; andstimulating the patient's muscle by delivering stimulating energy to the plurality of muscle stimulation electrodes.2. The method of wherein the placement of the first and second thermal elements occurs sequentially.3. The method of further comprising activating the second thermal source to further change the temperature of the tissue.4. The method of wherein the step of positioning the first thermal element activates the first thermal source to cause a temperature change in the patient's tissue.5. The method of wherein positioning the first thermal element comprises positioning a cooling pack relative to a patient proximate the plurality of electrodes to thereby activate the first thermal source and cause a temperature change in the patient's tissue.6. The method of wherein positioning a first thermal element associated with a first thermal source comprises positioning a first thermal element contained within the second thermal element.7. The method of wherein positioning a plurality of muscle stimulation electrodes on a patient comprises positioning a stimulation pad comprising the plurality of muscle stimulation electrodes on the patient claim 1 , and wherein the pad comprises the first thermal element such that positioning the plurality of muscle stimulation electrodes ...

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Номер записи: 72
16-01-2014 дата публикации

SYSTEM AND METHOD FOR THE TREATMENT OF HEART TISSUE

Номер: US20140018891A1
Автор: Laufer Michael D.
Принадлежит:

A device is disclosed for locating and treating an infarct scar in a heart. The device includes a catheter, a collapsible heater and energizing means connected to the collapsible heater for energizing the collapsible heater to raise the temperature of the infarct scar to a temperature sufficient to reduce the surface area of the infarct scar. 1. A method for treating an infarct scar in a heart , comprising the steps of: introducing a catheter into the heart; placing a heating element through the catheter and adjacent to the infarct scar; and , energizing the heating element to raise the temperature of the infarct scar.2. A method according to wherein the step of energizing the heating element comprises controllably energizing the heating element to raise the temperature of the scar to a controlled temperature.3. A method according to further comprising the steps of repeating the placing and energizing steps to treat the entire infarct scar surface.4. A method according to wherein the step of energizing the heating element raises the temperature of the infarct scar to a temperature sufficient to reduce the surface area of the infarct scar.5. A method according to wherein said heating element is placed in contact with the infarct scar.6. The method of wherein the heating element is energized by applying radio frequency energy.7. The method of wherein the heating element is energized by resistive heating.8. The method of wherein the scar is energized to a temperature in the range of about 40 degrees Celsius to about 75 degrees Celsius.9. A device for treating an infarct scar in a heart claim 1 , comprising: a catheter; a collapsible heater connected to said catheter; and claim 1 , energizing means connected to said collapsible heater for energizing at least a portion of the collapsible heater to raise the temperature of the infarct scar.10. A device according to wherein said collapsible heater is connected to the distal end of a cable.11. A device according to wherein ...

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Номер записи: 73
23-01-2014 дата публикации

DEVICES AND METHODS TO REDUCE MYOCARDIAL REPERFUSION INJURY

Номер: US20140025143A1
Автор: Atkinson Robert, Galdonik Jason, Keith Peter, McLean Paul
Принадлежит: Prospex Medical III

Devices and methods that mitigate reperfusion injury (RI) in a clinically practical manner so as to avoid significantly increasing time to reperfusion. In general, these systems and methods involve an antegrade approach to deliver a fluid to the myocardium at risk of RI before, during and after reperfusion is established by a percutaneous coronary intervention such as aspiration and stenting. 1. A method of treating a patient , comprising:a) advancing a catheter across an occlusion in a coronary artery;b) infusing a chilled liquid via the catheter distal of the occlusion before reperfusion;c) aspirating the occlusion to establish reperfusion while continuing to infuse the chilled fluid during reperfusion;d) retracting the catheter proximally and/while continuing to infuse the chilled fluid proximal of the occlusion; ande) dilating the occlusion while continuing to infuse the chilled fluid.2. A method as in claim 1 , wherein the chilled liquid is infused at a first flow rate before the occlusion is aspirated and a second flow rate after the occlusion is aspirated claim 1 , wherein the first flow rate is less than the second flow rate.3. A method as in claim 1 , wherein the chilled liquid is infused at a first flow rate before the occlusion is dilated and a second flow rate after the occlusion is dilated claim 1 , wherein the first flow rate is less than the second flow rate.4. A method as in wherein the chilled liquid is infused before aspiration and continuously during aspiration.5. A method as in wherein the chilled liquid is infused before dilation and continuously during dilation.6. A method as in wherein the chilled liquid is infused after dilation.7. A method as in claim 1 , wherein the chilled liquid is provided via an insulated line set connecting a source of pressurized chilled liquid to a proximal end of the catheter claim 1 , and wherein the pressurized chilled liquid is recirculated via the insulated line set through the source of pressurized chilled ...

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Номер записи: 74
23-01-2014 дата публикации

ICY EYEWEAR

Номер: US20140025144A1
Автор: Ragan Cindy Robin
Принадлежит:

An icy eyewear apparatus comprising: a front sinusoidal rim having a convex section in its center, and two concave sections, such that, when the icy eyewear apparatus is worn by the user, each concave section mirrors the shape of the bottom of the eye of the user from the respective side and each concave section lies proximate to the bottom of the respective eye, such that the user's vision is not obstructed; two temple pieces, one temple piece associated with each side, such that, when the icy eyewear apparatus is worn by the user, the two temple pieces hold the icy eyewear apparatus in place by securing it to the ears of the user; and, two icy packets, one icy packet attached to each concave section of the front sinusoidal rim, such that, the icy packets rest on the swollen areas below the eyes of the user. 1. An icy eyewear apparatus comprising: a front sinusoidal rim having a convex section in its center , which , when the icy eyewear apparatus is worn by a user , rests on the nose of the user , such that it supports most of the weight of the icy eyewear apparatus , and two concave sections , one on each side , left and right , of the convex section , such that , when the icy eyewear apparatus is worn by the user , each concave section corresponds to the shape of the bottom of the eye of the user from the respective side and each concave section lies proximate to the bottom of the respective eye , such that the user's vision is not obstructed; two temple pieces , one temple piece associated with each side , left and right , of the front sinusoidal rim , such that , together , when the icy eyewear apparatus is worn by the user , the two temple pieces hold the icy eyewear apparatus in place by securing it to the ears of the user; and , two icy packets , one icy packet attached to each concave section of the front sinusoidal rim , such that , when the icy eyewear apparatus is worn by the user , the icy packets rest on the swollen areas below the eyes of the user.2. ...

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Номер записи: 75
23-01-2014 дата публикации

SEGMENTED ICE WRAP

Номер: US20140025145A1
Автор: Kirkman Christopher
Принадлежит:

A device for transferring heat from a body part includes a segmented pouch formed from upper and lower layers of plastic that are heat bonded together at their peripheries. A fluid port is established for the pouch to allow a fluid such as water to be introduced into the pouch. Within the pouch, a plurality of substantially coplanar pockets for holding a respective plurality of frozen fluid lumps are formed by selectively heat bonding the layers together. With this arrangement, the pouch and frozen fluid lumps establish an ice wrap that is sufficiently flexible to conform to a surface of the body. An elongated strap made of nonwoven fabric is attached to the pouch and a piece of hook fastener is affixed to the strap for engagement with the nonwoven fabric to secure the device when the strap is wrapped around the pouch and body part. 1. A device for transferring heat from a body part which comprises:a segmented pouch having a periphery, the pouch being formed with a plurality of substantially coplanar pockets for holding a respective plurality of frozen fluid lumps, wherein the pouch is flexible to conform the pouch against a surface of the body part;an elongated strap having a first end and a second end, and having a top side and a bottom side, wherein the first end of the strap is affixed to the periphery of the pouch; anda fastener attached to the top side of the strap and adjacent the first end of the strap wherein, with the segmented pouch positioned against the surface of the body part, the strap is folded over and across the pouch to secure the bottom side of the strap against the fastener to maintain the pouch against the surface of the body part for heat transfer therebetween.2. A device as recited in wherein the segmented pouch comprises:an upper layer having a periphery, wherein the periphery of the upper layer has a first section and a second section;a lower layer having a periphery dimensioned and sectioned substantially the same as the upper layer, ...

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Номер записи: 76
30-01-2014 дата публикации

Method and Apparatus for Inducing Therapeutic Hypothermia

Номер: US20140031631A1
Автор: HALL Gregory W., Seidman Daniel P.
Принадлежит:

Methods and apparatus for delivering therapeutic hypothermia to a patient are provided which may include any number of features. One feature is a hypothermia system comprising a fluid source, a heat exchanger assembly, a catheter in fluid communication with the fluid source, and a pump system configured to infuse hypothermic fluid into a patient cavity and extract hypothermic fluid from the patient cavity. The hypothermia system can infuse and extract fluid automatically from the patient cavity. In one embodiment, the patient cavity is a peritoneal cavity. A safe access device to gain access to the patient cavity is also provided. 1. An access device configured to gain access into a cavity of a patient , comprising:an elongate shaft having a distal tip;a lumen extending through the elongate shaft;a fluid source in fluid communication with the lumen, the fluid source configured to detect entry into the cavity of the patient by releasing a volume of fluid into the cavity when the distal tip gains access to the cavity.2. The access device of further comprising threads on the elongate shaft.3. The access device of wherein the fluid source holds between 5 ml and 60 ml of fluid.4. The access device of wherein the fluid source holds at least 50 ml of fluid.5. The access device of further comprising a lubricious coating on the elongate shaft.6. The access device of further comprising an ultrasound coating on the elongate shaft.7. The access device of further comprising a thrombogenic coating on the elongate shaft.8. The access device of wherein the distal tip has a diameter between 5 mm and 12 mm.9. The access device of wherein the elongate shaft comprises a plastic.10. The access device of further comprising a sensor configured to detect release of the fluid from the fluid source into the cavity.11. The access device of further comprising a taper disposed near a proximal end of the elongate shaft claim 1 , the taper configured to mate with the fluid source.12. The access ...

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Номер записи: 77
06-02-2014 дата публикации

METHODS AND DEVICES FOR CONTROLLING BLOOD PERFUSION PRESSURE ALONG WITH REGIONAL MILD HYPOTHERMIA

Номер: US20140039538A1
Автор: Kassab Ghassan S., Navia, SR. Jose A.
Принадлежит:

Methods and devices for controlling blood perfusion pressure along with regional mild hypothermia. In at least one embodiment of a device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area, and a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough. 1. A perfusion device , comprising:an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure;a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area; anda regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough.2. The device of claim 1 , wherein the regional hypothermia system is further operable to reduce and/or regulate a temperature of a portion of a mammalian body claim 1 , the portion selected from the group consisting of a vessel claim 1 , a tissue claim 1 , and an organ.3. The device of claim 1 , wherein the regional hypothermia system comprises a ...

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Номер записи: 78
06-02-2014 дата публикации

COLD THERAPY DEVICE WITH INDIVIDUAL COMPARTMENTS

Номер: US20140039585A1
Автор: Kelso Eric R., Stienmier J. David
Принадлежит: Talus Research + Design, LLC

A cold therapy apparatus, a cold therapy system and a method of using a cold therapy apparatus, including a method for lowering the body temperatures in a subject. 137-. (canceled)38. A cold therapy apparatus for cooling a subject , the cold therapy apparatus comprising a plurality of individual compartments , each of the plurality of individual compartments containing at least two components that cause an endothermic reaction when mixed together , at least one of the components being in liquid form and separated from the at least one other component until activated , each individual compartment being individually activatable to activate the endothermic reaction.39. The cold therapy apparatus of wherein one of the at least two components is water.40. The cold therapy apparatus of wherein the at least two components are separated from each other by a frangible membrane.41. The cold therapy apparatus of wherein there are three of the individual compartments.42. The cold therapy apparatus of wherein a barrier is present intermediate each of the plurality of individual compartments.43. The cold therapy apparatus of further including an attachment device for securing the apparatus to a subject.44. A cold therapy apparatus for cooling a subject claim 38 , the cold therapy apparatus comprisinga plurality of individual compartments, each of the plurality of individual compartments containing at least two components that cause an endothermic reaction when mixed together, at least one of the components being in liquid form and separated from the at least one other component until activated, each individual compartment being individually activatable to activate the endothermic reaction; anda water compartment disposed between a subject and the plurality of individual compartments for transferring heat from a subject to the plurality of individual compartments.45. The cold therapy apparatus of wherein the water compartment is comprised of a plurality of individual sub- ...

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Номер записи: 79
20-02-2014 дата публикации

STIMULUS GENERATION APPARATUS

Номер: US20140051905A1
Автор: HIRABAYASHI TAKAYUKI, Nakamura Takatoshi, SAITOU MAIKO, Sakai Hideki, SAKO Yoichiro
Принадлежит: SONY CORPORATION

There is provided a stimulus generation apparatus including a stimulus generation section which provides a stimulus for promoting fat burning for fat or a satiety center inside a body cavity. 1. A stimulus generation apparatus comprising:a stimulus generation section which provides a stimulus for promoting fat burning for fat or a satiety center inside a body cavity.2. The stimulus generation apparatus according to claim 1 ,wherein the stimulus generation section generates at least a mechanical, electrical, magnetic, or chemical stimulus.3. The stimulus generation apparatus according to claim 1 ,wherein the stimulus generation section provides the stimulus by vibration, pressure, electricity, magnetism, or temperature change.4. The stimulus generation apparatus according to claim 1 , further comprising:an imaging section which images inside the body cavity; anda fat specification section which specifies the fat or a surrounding of the fat inside the body cavity by analyzing a picked-up image imaged by the imaging section,wherein the stimulus generation section continuously or intermittently provides the stimulus for the fat or the surrounding of the fat specified by the fat specification section.5. The stimulus generation apparatus according to claim 4 ,wherein the fat specification section specifies a brown fat cell by analyzing a color of the picked-up image, andwherein the stimulus generation section provides the stimulus for a range which includes the brown fat cell.6. The stimulus generation apparatus according to claim 1 ,wherein the fat is a visceral fat or a vascular fat.7. The stimulus generation apparatus according to claim 1 ,wherein the stimulus generation section is a balloon capable of expanding or contracting in a stomach so as to provide the stimulus for promoting the fat burning for the satiety center, andwherein the stimulus generation apparatus further includes:a stop section for remaining at a prescribed part inside the body cavity; anda balloon ...

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Номер записи: 80
20-02-2014 дата публикации

SYSTEMS AND METHODS FOR SELECTIVE AUTO-RETROPERFUSION ALONG WITH REGIONAL MILD HYPOTHERMIA

Номер: US20140052224A1
Автор: Kassab Ghassan S., Navia, SR. Jose A.
Принадлежит:

Systems and methods for selective auto-retroperfusion along with regional mild hypothermia. In at least one embodiment of a system for providing a retroperfusion therapy to a venous vessel of the present disclosure, the system comprises a catheter for controlling blood perfusion pressure, the catheter comprising a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, and at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen, and adapted to move between an expanded configuration and a deflated configuration, and a flow unit for regulating the flow and pressure of a bodily fluid, and a regional hypothermia system operably coupled to the catheter, the regional hypothermia system operable to reduce and/or regulate a temperature of the bodily fluid flowing therethrough. 1. A system , comprising: a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, and', 'at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen, and adapted to move between an expanded configuration and a deflated configuration; and, 'a catheter for controlling blood perfusion pressure, the catheter comprisinga flow unit for regulating the flow and pressure of a bodily fluid; anda regional hypothermia system operably coupled to the catheter, the regional hypothermia system operable to reduce and/or regulate a temperature of the bodily fluid flowing therethrough.2. The system of claim 1 , wherein the regional hypothermia system is further operable to reduce ...

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Номер записи: 81
27-02-2014 дата публикации

BLOOD FLOW RATE MEASUREMENT SYSTEM

Номер: US20140058277A1
Автор: Lam Cheong Ming, Tan Seng Sing
Принадлежит: Nanyang Polytechnic

The present invention discloses a heat exchanging assembly with a body adaptable to a catheter for measuring blood flow rate with a supply system for providing the heat exchanging medium to the heat exchanging assembly at a constant temperature and constant flow rate. The heat exchanging assembly comprises a heat exchanging element, a plurality of temperature sensors, a sensor lumen and an inflation lumen. 1. A system for maintaining a heat-exchanging medium at a constant temperatur and at a constant flow rate comprising:a reservoir;a pump connected to said reservoir by a first path wherein said pump pumps heat-exchanging medium out of said reservoir;a cooling apparatus connected to said pump by a second path and connected to said reservoir by a third path wherein said cooling apparatus cools said heat-exchanging medium pumped out of said reservoir;a valve located in said third path wherein a first configuration of said valve allows said cooled heat-exchanging medium to flow along said third path to said reservoir and a second configuration of said valve redirects said cooled heat-exchanging medium from said third path to a fourth path;a catheter, connected to said valve by said fourth path; anda fifth path with a first end connected to said reservoir and a second end connected to said catheter wherein said cooled heat-exchanging medium flows from said catheter to said reservoir along said fifth path.2. The system of wherein said valve is located proximate said cooling apparatus to ensure said cooled heat-exchanging medium flowing to said catheter along said fourth path is at a stabilised cooled temperature.3. The system of wherein said cooling apparatus comprises a fan.4. The system of wherein said cooling apparatus comprises a peltier cooler.5. The system of wherein said pump comprises an electric pump connected to a power supply to circulate said heat-exchanging medium in said system.6. The system of wherein each of said first claim 1 , second claim 1 , third ...

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Номер записи: 82
27-02-2014 дата публикации

SECURABLE ICE PACK DEVICE

Номер: US20140058486A1
Автор: JR. Wardell, Moore
Принадлежит:

An ice pack device that may be secured to an appendage to be treated. The ice pack device may include a body portion that includes an ice pack compartment. The ice pack compartment may secure ice, refrigerant gel, or liquids. Extending from the body portion may be at least one first strap and at least one second strap. The ice pack device may be secured to the appendage by wrapping the straps around the appendage and releasably connecting them. 1. An ice pack device comprising:a body portion comprising a first side, a second side, a top end, a bottom end, a front surface, and a rear surface wherein the body portion comprises an ice pack compartment; andat least one first strap extending from the first side of the body portion and at least one second strap extending from the second side of the body portion.2. The ice pack device of claim 1 , further comprising a connector releasably connecting the first strap and the second strap.3. The ice pack device of claim 1 , wherein the at least one first strap comprises two straps and the at least one second strap comprises two straps.4. The ice pack device of claim 2 , wherein the connector comprises at least one of a hook and loop fastener claim 2 , a clip claim 2 , a button claim 2 , a snap button claim 2 , and a coupler.5. The ice pack device of claim 1 , wherein the first strap comprises a hook component on a rear surface and the second strap comprises a loop component on a front surface claim 1 , wherein the hook and loop components releasably attach.6. The ice pack device of claim 1 , wherein the ice pack compartment forms an opening near the top end and front surface of the body portion claim 1 , wherein the opening is formed to receive ice.7. The ice pack device of claim 6 , further comprising a connector that opens and closes the opening.8. The ice pack device of claim 7 , wherein the connector is a hook and loop fastener.9. The ice pack device of claim 1 , wherein the ice compartment comprises a refrigerant gel.10. ...

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Номер записи: 83
06-03-2014 дата публикации

RESPIRATORY SYSTEM FOR INDUCING THERAPEUTIC HYPOTHERMIA

Номер: US20140060534A1
Автор: Belson Amir
Принадлежит: THERMOCURE, INC.

The present invention provides a method and apparatus for controlling a patient's body temperature and in particular for inducing therapeutic hypothermia. Various embodiments of the system are described. The system includes: a source of breathing gas, which may be in the form of a compressed breathing gas mixture; a heat exchanger or other heating and/or cooling device; and a breathing interface, such as a breathing mask or tracheal tube. Optionally, the system may include additional features, such as a mechanical respirator, a nebulizer for introducing medication into the breathing gas, a body temperature probe and a feedback controller. The system can use air or a specialized breathing gas mixture, such as He/Oor SF/Oto increase the heat transfer rate. In addition, the system may include an ice particle generator for introducing fine ice particles into the flow of breathing gas to further increase the heat transfer rate. 1introducing fine ice particles into a flow of breathing gas;and delivering the flow of breathing gas containing the fine ice particles to the patient.. A method for inducing therapeutic hypothermia in a patient, comprising: This application is a continuation of U.S. patent application Ser. No. 13/326,101 (Attorney Docket No. 32138-703.401), filed Dec. 14, 2011, which is a divisional of U.S. patent application Ser. No. 10/587,103 (Attorney Docket No. 32138-703.831), filed Jul. 9, 2008, which is a National Stage Entry of PCT/US2005/002600 (Attorney Docket No. 32138-703.601), filed Jan. 24, 2005, which claims the benefit of Provisional Application No. 60/538,789 (Attorney Docket No. 32138-703.101), filed Jan. 22, 2004, the full disclosures of which are incorporated herein by reference.The present invention relates generally to apparatus and methods for selective modification and control of a patient's body temperature. More particularly, it relates to a respiratory system and methods for raising and lowering a patient's body temperature by heat ...

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Номер записи: 84
06-03-2014 дата публикации

DEVICES, SYSTEMS, AND METHODS FOR CONTROLLING TEMPERATURE IN PEDIATRIC SUBJECTS

Номер: US20140067026A1
Автор: Kulstad Erik, Shanley Patrick
Принадлежит: Advanced Cooling Therapy, LLC

Methods, devices, and systems for temperature management of a pediatric patient in a perioperative environment are disclosed. Methods, devices, and systems for maintaining normothermia in a pediatric patient in a perioperative environment are disclosed. The use of esophageal heat transfer devices for perioperative temperature management and/or maintenance of normothermia in a pediatric patient is disclosed. 1. A method for temperature management of a pediatric subject in a perioperative environment , comprising controlling body temperature of the subject via esophageal cooling or warming.2. The method of claim 1 , further comprising orally or nasally inserting an esophageal heat transfer device in the subject.3. The method of claim 2 , wherein the esophageal heat transfer device comprises a fluid path defined by one or more lumens.4. The method of claim 3 , further comprising flowing a heat transfer medium along the fluid path for a time sufficient to control body temperature of the subject.5. The method of claim 1 , wherein the perioperative environment comprises an ambient temperature of about 21° C. or less.6. The method of claim 1 , wherein the pediatric subject is less than about 26 kg.7. A method for maintaining normothermia in a pediatric subject in a perioperative environment claim 1 , comprising contacting a heat transfer region of an esophageal heat transfer device with esophageal tissue of the subject.8. The method of claim 7 , wherein the esophageal heat transfer device comprises an input port for receiving a heat transfer medium from an external source.9. The method of claim 7 , further comprising orally or nasally inserting the esophageal heat transfer device in the pediatric subject.10. The method of claim 7 , wherein the esophageal heat transfer device comprises a fluid path defined by one or more lumens.11. The method of claim 10 , further comprising flowing a heat transfer medium along the fluid path for a time sufficient to maintain normothermia ...

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Номер записи: 85
06-03-2014 дата публикации

Heating/cooling system for indwelling heat exchange catheter

Номер: US20140067027A1
Автор: Stelica Stelea, Wayne Noda
Принадлежит: Zoll Circulation Inc

A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.

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Номер записи: 86
20-03-2014 дата публикации

LARYNGEAL MASK

Номер: US20140076309A1
Автор: Hashimoto Hiroshi, Kokubu Masatomo, Morita Kiyoshi, Takeda Yoshimasa
Принадлежит:

A laryngeal mask is provided with an outer tube and a connector, having a base end in which is formed a first connecting portion capable of being connected to an artificial respirator and a leading end in which is formed a ventilation opening, the outer tube and the connector having a communication passage formed therein that communicates between the first connecting portion and the ventilation opening, a ring-shaped cuff capable of tightly adhering to a tracheal opening of a patient trachea as a result of inflating in a state where the ring-shaped cuff is inserted to a predetermined insertion position, and hyoid bone-contacting portions and protruding laterally from the outer tube so as to contact from above a site in a pharyngeal portion of the patient corresponding to a hyoid bone of the patient in a state where the ring-shaped cuff is inserted to the insertion position. 1. A laryngeal mask for securing an airway of a patient , comprising:an insertion tube including a base end in which is formed a connecting portion capable of being connected to an artificial respirator, a leading end in which is formed a ventilation opening, and a communication passage formed therein that communicates between the connecting portion and the ventilation opening;a ring-shaped cuff which is attached to the leading end of the insertion tube so as to surround the ventilation opening, and is capable of tightly adhering to a tracheal opening of a patient trachea as a result of inflating in a state where the ring-shaped cuff is inserted to a predetermined insertion position in the patient; andat least one hyoid bone-contacting portion that protrudes laterally from the insertion tube so as to contact from above a site, in a pharyngeal portion of the patient, corresponding to a hyoid bone of the patient in a state where the ring-shaped cuff is inserted to the insertion position.2. The laryngeal mask according to claim 1 , wherein the at least one hyoid bone-contacting portion includes two ...

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Номер записи: 87
20-03-2014 дата публикации

PERIORBITAL EDEMA REDUCTION DEVICE

Номер: US20140081361A1
Автор: Dhayan Ishigaki
Принадлежит: KARSTARK LTD.

A portable head-mounted device for cooling the under-eye area of skin, said device comprising at least one cooling element arranged to be located adjacent the skin of the under-eye area when the device is mounted to the head, the cooling element having a first side that faces the under-eye area of skin when the device is mounted to a head and a second side that faces away from the skin of the under-eye area; said at least one cooling element comprising: liquid retaining means adapted to retain a liquid provided thereto; and heat transfer means adapted to transfer heat by conduction to a liquid retained by the liquid retaining means to promote evaporation of said liquid thereby providing a cooling effect when the device is mounted to the head in use 1. A portable head-mountable device for cooling the under-eye area of skin , said device comprising at least one cooling element arranged to be located adjacent the skin of the under-eye area when the device is mounted to the head , the cooling element having a first side configured to faces the under-eye area of skin when the device is mounted to a head and a second side configured to faces away from the skin of the under-eye area;said at least one cooling element comprising:liquid retaining means adapted to retain a liquid provided thereto; andheat transfer means adapted to transfer heat by conduction to a liquid retained by the liquid retaining means to promote evaporation of said liquid thereby providing a cooling effect when the device is mounted to the head in use.2. The device of wherein the cooling element is arranged such that a liquid retained by said liquid retaining means may come into contact with the skin of the under-eye area when the device is worn in use.3. The device as claimed in claim 1 , further comprising at least one reservoir for holding a liquid to be supplied to the liquid retaining means claim 1 , wherein said at least one reservoir is in fluid communication with said at least one cooling ...

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Номер записи: 88
27-03-2014 дата публикации

METHODS AND DEVICES TO TREAT NASAL AIRWAYS

Номер: US20140088463A1
Автор: Frazier Andrew, Wolf Scott J.
Принадлежит: AERIN MEDICAL, INC.

A method is described for modifying at least one property of a tissue of or near a nasal valve of a nose, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in a nasal airway. The method may involve contacting a treatment element of a treatment device with the at least one tissue inside the nasal airway, with sufficient force to at least temporarily deform the at least one tissue, applying energy to, or removing energy from, the at least one tissue, using the treatment element, and removing the treatment element from the nostril. 1. A method of modifying at least one property of at least one tissue of or near a nasal valve of a nose , without using a surgical incision or an implant , to decrease airflow resistance or perceived airflow resistance in a nasal airway , the method comprising:contacting a treatment element of a treatment device with the at least one tissue inside the nasal airway, with sufficient force to at least temporarily deform the at least one tissue;applying energy to, or removing energy from, the at least one tissue, using the treatment element; andremoving the treatment element from the nostril.2. A method as in claim 1 , wherein the treatment element has a convex shape claim 1 , such that contacting the treatment element against the at least one tissue at least temporarily deforms the tissue into a concave shape.3. A method as in claim 2 , wherein contacting the treatment element with the tissue causes at least one protrusion on the treatment element to deform the tissue.4. A method as in claim 1 , wherein applying energy comprises applying energy in a form selected from the group consisting of ultrasound claim 1 , microwave claim 1 , heat claim 1 , radiofrequency claim 1 , electrical claim 1 , light and laser.5. A method as in claim 4 , wherein applying energy comprises delivering radiofrequency energy to one or more electrodes of the treatment element to locally heat the at least one ...

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Номер записи: 89
27-03-2014 дата публикации

Devices and methods for vestibular and/or cranial nerve stimulation

Номер: US20140088671A1
Автор: Lanty L. Smith, Lesco L. Rogers
Принадлежит: Scion Neurostim Inc

An in-ear stimulator for administering thermal stimulation to the ear canal of a subject includes (a) an earpiece configured to be insertable into the ear canal of said subject, the earpiece having an outer surface and an internal cavity formed therein, the internal cavity having an inner surface; and (b) at least one thermoelectric device thermally coupled to the earpiece internal cavity inner surface.

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Номер записи: 90
03-04-2014 дата публикации

INTRAVASCULAR HEAT EXCHANGE CATHETER WITH RIB CAGE-LIKE COOLANT PATH

Номер: US20140094883A1
Автор: Gurukula Venkata Vishnu, HELKOWSKI Richard A., Lim Alex L., MAFI Masouneh
Принадлежит: ZOLL CIRCULATION, INC.

An intravascular heat exchange catheter has serpentine-like supply and return conduits circulating working fluid with a heat exchange system to warm or cool a patient in which the catheter is intubated. 1. A catheter , comprising:a heat exchange supply conduit configured to supply working fluid received from a source of working fluid to a distal location;a heat exchange return conduit communicating with the supply conduit at the distal location and configured to return working fluid to the source;wherein at least a portion of the supply conduit and at least a portion of the return conduit are configured in a serpentine configuration when working fluid flow therethrough;wherein serpentine portions of the supply conduit establish axially longer segments and axially shorter segments and wherein serpentine portions of the return conduit establish axially longer segments and axially shorter segments, and further wherein at least one axially shorter segment of the return conduit is bordered by and axially between transverse legs of an axially longer segment of the supply conduit and at least one axially shorter segment of the supply conduit is bordered by and axially between transverse legs of an axially longer segment of the return conduit.2. The catheter of claim 1 , wherein at least when the conduits are inflated with working fluid claim 1 , a proximal-most transverse segment of the supply conduit ends at a first distally-extending axially-oriented segment claim 1 , which merges at a distal end with a second transverse segment claim 1 , which in turn merges at an opposite end of the second transverse segment with another distally-extending axially-oriented segment.3. The catheter of claim 2 , wherein at least when the conduits are inflated with working fluid claim 2 , a distal-most transverse segment of the return conduit ends at a first proximally-extending axially-oriented segment claim 2 , which merges at a proximal end with a second transverse segment claim 2 , ...

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Номер записи: 91
03-01-2019 дата публикации

THERMAL THERAPY GARMENT SYSTEM

Номер: US20190000159A1
Автор: Roberts Brandon
Принадлежит:

A thermal therapy garment system includes at least one garment assembly having a compression garment including an outer-surface, and an inner-surface having a plurality of pockets, and at least one thermal-insert. The plurality of pockets is located on the inner-surface of the compression garment and are strategically placed on the compression garment such that thermal therapy is enabled on at least one targeted area of a body of a user-wearer. The targeted area of the body of the user-wearer is at least one muscle, at least one joint, or a combination thereof. The compression garment may be worn underneath everyday clothing for all-day relief, enabling people to maintain a functional lifestyle. 1. A thermal therapy garment system comprising: [ an outer-surface; and', 'a plurality of pockets; and', 'an inner-surface having;'}], 'a compression garment including;'}, 'at least one thermal-insert;, 'at least one garment assembly having;'}wherein said at least one garment assembly comprises said compression garment and said at least one thermal-insert in functional combination, each of said at least one thermal-insert configured to fit within at least one of said plurality of pockets;wherein said plurality of pockets are located on said inner-surface of said compression garment, said plurality of pockets strategically placed on said compression garment such that thermal therapy is enabled on at least one targeted area of a body of a user-wearer;wherein said compression garment holds said at least one thermal-insert tightly against said targeted area of said body of said user-wearer, said at least one thermal-insert is concealed within the garment; andwherein said inner-surface is adjacent to said body of said user-wearer during an in-use condition.2. The thermal therapy garment system of claim 1 , wherein said targeted area of said body of said user-wearer is at least one muscle.3. The thermal therapy garment system of claim 2 , wherein said targeted area of said body of ...

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Номер записи: 92
07-01-2021 дата публикации

MEDICAL DEVICES WITH FLEXIBLE CIRCUIT ASSEMBLIES

Номер: US20210000539A1
Автор: GROFF JOEL N., Haverkost Patrick A., LINDQUIST JEFFREY S., SQUIRE ROBERT N., SUTERMEISTER DEREK C., Willard Martin R.
Принадлежит:

Medical devices for sympathetic nerve modulation are disclosed. An example medical device for sympathetic nerve modulation may include a catheter shaft having a distal region. An expandable member may be coupled to the distal region. A flexible circuit assembly may be attached to the expandable member. The flexible circuit assembly may include a first electrode strip, a second electrode strip, and a sensor strip disposed between the first electrode strip and the second electrode strip. The first electrode strip may include a first electrode. The second electrode strip may include a second electrode. The first electrode and the second electrode may define a pair of bipolar electrodes. 1. A medical device , comprising:a catheter shaft having a longitudinal axis;a balloon comprising a cylindrical balloon body coupled to the catheter shaft;a flexible circuit assembly coupled to the catheter shaft and the balloon, the flexible circuit assembly including two or more flexible strips;wherein each of the two or more flexible strips include one or more electrodes; andwherein at least a portion of the flexible circuit assembly that is positioned on the cylindrical body of the balloon is canted relative to the longitudinal axis of the catheter shaft.2. The medical device of claim 1 , wherein the portion of the flexible circuit assembly that is canted is oriented at an angle of 45 degrees or less relative to the longitudinal axis of the catheter shaft.3. The medical device of claim 1 , wherein the portion of the flexible circuit assembly that is canted is oriented at an angle of 5-30 degrees relative to the longitudinal axis of the catheter shaft.4. The medical device of claim 1 , wherein the two or more flexible strips include a first flexible strip comprising a plurality of electrodes and a second flexible strip comprising a plurality of electrodes.5. The medical device of claim 1 , wherein the two or more flexible strips include a first flexible strip comprising a plurality ...

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Номер записи: 93
03-01-2019 дата публикации

METHODS AND APPARATUS FOR THERMALLY-INDUCED RENAL NEUROMODULATION

Номер: US20190000545A1
Автор: Deem Mark, Gelfand Mark, GIFFORD, III Hanson, Levin Howard R., Wu Andrew, Zarins Denise
Принадлежит: Medtronic Ardian Luxembourg S.a.r.l.

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. In some embodiments, thermally-induced renal neuromodulation is achieved via delivery of a pulsed thermal therapy. 117-. (canceled)18. A method for treating a hypertensive human patient , the method comprising:intravascularly positioning a thermal apparatus carried by a renal denervation catheter at least proximate to renal nerves of the patient;delivering thermal energy via the thermal apparatus to modulate a function of the renal nerves via thermal effects; andintravascularly removing the renal denervation catheter from the patient after delivering the thermal energy to conclude the procedure.19. The method of wherein intravascularly positioning a thermal apparatus comprises intravascularly positioning the thermal apparatus within a renal artery of the patient proximate to the renal nerves.20. The method of wherein the renal denervation catheter comprises an expandable element at a distal region of the catheter claim 18 , and wherein the thermal apparatus is carried by the expandable element claim 18 , and wherein the method further comprises:transforming the expandable element from a low-profile delivery configuration to an expanded treatment configuration within a renal artery of the patient after intravascularly positioning the thermal apparatus at least proximate to renal nerves and before delivering ...

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Номер записи: 94
02-01-2020 дата публикации

Vaginal remodeling device and methods

Номер: US20200000517A1
Автор: Chun-Chih Cheng, Ian F. Smith, Jerome Jackson, Jonathan B. Parmer, Patrick Karl Howe, Sean Yasuo Sullivan, Sheree Leigh LUCAS, Stanley Levy, Steven Marc Lopez
Принадлежит: Viveve Inc

This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a handle and treatment tip that has both an energy delivery element and a cooling mechanism. The handle may be a two-handed handle allowing control even while rotating and maneuvering the treatment around the genital opening. The apparatus or system may also include an integrated controller, which may confirm tissue contact without applying RF energy, based only on the temperature of the applicator and the time since the last application of energy from the applicator.

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Номер записи: 95
02-01-2020 дата публикации

SYSTEM FOR INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE

Номер: US20200000519A1
Автор: Blanck Arthur G., Briggs Len, Gustus Rolfe Tyson, Hoey Michael F., Perry Mike, Stone Corbett W.
Принадлежит:

A catheter and catheter system may be used to treat disease tissue by gentle heating in combination with gentle or standard dilation. An elongate flexible catheter body with a radially expandable balloon having a plurality of electrodes engage tissue including diseased tissue when the structure expands. 1. A system , comprising:a catheter body having a proximal end and a distal end with an axis therebetween;a radially expandable member having a low profile insertion configuration and a larger profile configuration; anda plurality of electrode pairs included on a plurality of flexible circuits, the flexible circuits distributed about an outer surface of the expandable member, so as to define a plurality of remodeling zones extending circumferentially about a wall of a body lumen when the expandable member is in the larger profile configuration; andwherein the plurality of electrode pairs is configured to transmit a tissue remodeling energy to each of the plurality of remodeling zones such that the tissue remodeling energy transmitted to remodeling zones including both a target tissue and a collateral tissue heats the target tissue sufficiently to efficaciously alter the target tissue without causing thermal damage to the collateral tissue.2. The system of claim 1 , wherein each of the flexible circuits includes an associated bipolar electrode pair.3. The system of claim 2 , wherein the electrodes of each bipolar electrode pair are disposed on its associated flexible circuit so as to have a predetermined bipolar pair separation distance therebetween when the expandable member is in the larger profile configuration.4. The system of claim 2 , wherein the bipolar electrode pairs are configured to be energized with RF energy claim 2 , and wherein the electrodes of the electrode pairs are circumferentially separated.5. The system of claim 4 , wherein a circumferential distance between the electrodes of the electrode pairs is within a range from about 0.25 to 2.5 mm.6. The ...

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Номер записи: 96
07-01-2021 дата публикации

DUAL MODALITY ENERGY DELIVERY SYSTEM

Номер: US20210000644A9
Автор: DENG AUSTIN, Higgins Laura, Paunescu Alexandru, Walsh Ryan
Принадлежит:

An economical dual modality system is useful in a system for independent delivery of two distinct energy modalities to a mammalian body and includes a thermal subsystem. The thermal subsystem includes a thermal source affixed to flexible web having an adhesive surface and at least one structure arranged and configured to couple the thermal subsystem to a chassis comprising a durable energy subsystem. 1. A thermal subsystem for use with a system for independent delivery of two distinct energy modalities to a mammalian body , the thermal subsystem comprising a thermal source affixed to flexible web having an adhesive surface and at least one structure arranged and configured to couple the thermal subsystem to a chassis comprising a durable energy subsystem.2. The thermal subsystem of wherein the at least one structure arranged and configured to couple the thermal subsystem to the chassis comprises at least one clip claim 1 , at least one aperture claim 1 , or at least one snap.3. The thermal subsystem of wherein the thermal source comprises a heat source.4. The thermal subsystem of wherein the thermal source comprises a cooling source.5. The thermal subsystem of further comprising one or more sensors disposed on either the chassis or the replaceable thermal subsystem. The present invention generally relates to a system which utilizes light therapy in the treatment of musculoskeletal pain, reduction of edema and inflammation, and promoting the healing of tissues, especially soft tissues like muscle, tendons, and ligaments. More specifically, the invention relates to a system with a durable energy subsystem, a replaceable thermal subsystem, and a means to couple the durable energy subsystem and the replaceable thermal subsystem to a desired treatment area of a user's body.Light, when delivered to the body, has been shown to elicit a wide range of therapeutic effects. Specifically, light can be used as a therapeutic agent for various disorders. For example, light therapy ...

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Номер записи: 97
07-01-2016 дата публикации

Pain Management Using Cryogenic Remodeling

Номер: US20160000601A1
Автор: Keith Burger, Lisa Elkins, Ronald Williams
Принадлежит: MyoScience Inc

Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated.

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Номер записи: 98
03-01-2019 дата публикации

TREATMENT SYSTEMS FOR REMOVING HEAT FROM SUBCUTANEOUS LIPID-RICH CELLS

Номер: US20190000663A1
Автор: Anderson Richard Rox, Manstein Dieter
Принадлежит:

The present invention relates to methods for use in the selective disruption of lipid-rich cells by controlled cooling. The present invention further relates to a device for use in carrying out the methods for selective disruption of lipid-rich cells by controlled cooling. 1. A system for removing heat from subcutaneous lipid-rich cells of a region of a subject , the system comprising a treatment system including at least one cooling/heating element and configured to wrap around at least a portion of the subject such that the system is capable of reducing a temperature of the region to damage the subcutaneous lipid-rich cells while not injuring non-lipid-rich cells proximate to the at least one cooling/heating element.2. The system of wherein the treatment system is configured to at least partially surround one or more selected from the group consisting of: an arm claim 1 , an upper or lower leg claim 1 , and a waist of the subject.3. The system of wherein the treatment system is configured to form a band or cylinder around the portion of the subject.4. The system of wherein the portion of the subject includes one or more selected from the group consisting of: an arm claim 1 , an upper or lower leg claim 1 , and a waist of the subject.5. The system of wherein the treatment system comprises a flexible material that allows the treatment system to wrap around the portion of the subject.6. The system of wherein the treatment system includes a fastening mechanism that couples together ends of the treatment system.7. The system of wherein the at least one cooling/heating element includes a plurality of cooling/heating elements arranged circumferentially about the portion of the subject when the treatment system wraps around the portion of the subject.8. The system of wherein the treatment system includes at least one passage through which a fluid is capable of flowing to change the temperature of the subcutaneous lipid-rich cells.9. The system of wherein the fluid ...

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Номер записи: 99
03-01-2019 дата публикации

Connectable catheter system

Номер: US20190000667A1
Автор: Gil Hakim, Nadav MALCHI, Yosh DOLLBERG
Принадлежит: Urogen Pharma Ltd

There are provided a connectable catheter system, device and methods of use thereof. The connectable catheter system, comprising: an intermediary catheter and a reconnectable indwelling stent wherein the intermediary catheter and the indwelling stent are configured to connect, within a subject body to form a continuous fluid conduit between the intermediary catheter and the reconnectable indwelling stent and to further allow controlled release of substances and/or heating of internal target regions.

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Номер записи: 100