КОМПОЗИЦИИ ДЛЯ ГИГИЕНЫ ПОЛОСТИ РТА И СПОСОБЫ

Группа изобретений относится к медицине, а именно к стоматологии, и может быть использована для лечения состояний, связанных с повышенной экспрессией ММП-13, выбранных из группы, состоящей из потери фиксации одного или более зубов, выпадения зубов, подвижности зубов, образования карманов, потери костной ткани и комбинации двух и более указанных состояний. Для этого предложено применение 4-ацетамидофенил 2-изопропил-5-метилциклогексилкарбоната в производстве лекарственного средства для лечения этих состояний. Предложена также композиция для ухода за зубами, содержащая орально приемлемый носитель и терапевтически эффективное количество ингибитора ММП-13 в виде 4-ацетамидофенил 2-изопропил-5-метилциклогексилкарбоната. Группа изобретений обеспечивает эффективное лечение указанных состояний за счёт эффективного подавления ММП-13. 2 н. и 1 з.п. ф-лы, 5 табл., 5 пр.

КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ СМЕСЬ ЭКСТРАКТОВ РАСТЕНИЙ ИЛИ СМЕСЬ МОЛЕКУЛ, СОДЕРЖАЩИХСЯ В УКАЗАННЫХ РАСТЕНИЯХ, И ПРИМЕНЕНИЕ ДЛЯ КОНТРОЛИРОВАНИЯ МЕТАБОЛИЗМА УГЛЕВОДОВ И/ИЛИ ЛИПИДОВ

Группа изобретений относится к фармацевтической промышленности, а именно к композиции для профилактики или лечения расстройств метаболизма углеводов и/или жиров у человека или животных. Композиция для профилактики или лечения расстройств метаболизма углеводов и/или жиров у человека или животных, содержащая, по меньшей мере, смесь молекул, состоящую по меньшей мере из водно-спиртового экстракта Chrysanthellum indicum, полученного из целого растения и/или надземных частей Chrysanthellum indicum, и водного экстракта Cynara scolymus, полученного из листьев Cynara scolymus, и водно-спиртового экстракта Vaccinium myrtillus, полученного из плода Vaccinium myrtillus, водно-спиртового экстракта Olea europaea, полученного из листьев Olea europaea, и синтетического пиперина и/или экстракта Piper, содержащего пиперин, в определенном количестве. Композиция для профилактики или лечения расстройств метаболизма углеводов и/или жиров у человека или животных, содержащая, по меньшей мере, смесь дикофеилхинной ...

Композиция для повышения качества спермы у субъекта мужского пола

Настоящее изобретение относится к фармацевтической промышленности, а именно к композиции для улучшения качества спермы у субъекта мужского пола. Композиция для улучшения качества спермы у субъекта мужского пола, содержащая i) сухой препарат I из корневищ Alpinia galanga или Alpinia conchigera, содержащий по меньшей мере 2% по массе 1'S-1'-ацетоксихавиколацетата, и ii) растительный экстракт II, содержащий соединения с антиоксидантной активностью, получаемые из Punica granatum, где отношение (вес./вес.) между сухим препаратом I и экстрактом II находится в диапазоне от 10:1 до 1:10. Способ лечения мужского бесплодия, обусловленного низким числом сперматозоидов и/или низкой подвижностью сперматозоидов. Набор для улучшения качества спермы у субъекта мужского пола. Вышеописанная композиция эффективна для улучшения качества спермы у субъекта мужского пола. 3 н. и 15 з.п. ф-лы, 4 ил., 8 табл., 6 пр.

Средство для лечения и профилактики послеродового эндометрита и цервицита у коров

Изобретение относится к ветеринарной медицине, в частности к средству для лечения и профилактики послеродового эндометрита и цервицита у коров. Средство содержит компоненты в следующим соотношении, мас.%: клевер красный - 25-30; ортилия однобокая - 10-15; ромашка аптечная - 5-10; крапива двудомная - 5-10; тысячелистник обыкновенный - 5-10; раствор люголя с глицерином - 15-20; кокосовое масло - 5-10; 40% водно-спиртовой раствор - до 100%. Вышеописанное средство позволяет проводить лечение и профилактику послеродового эндометрита и цервицита у коров при терапевтической эффективности 100%. 3 табл., 1 пр.

Способ получения сухого растительного экстракта

Изобретение относится к способу получения сухого растительного экстракта для фармацевтической, парфюмерно-косметической промышленности. Способ получения сухого растительного экстракта, характеризующийся тем, что после подготовки сырья, в качестве которого используют в мас.ч. побеги багульника болотного - 0,8-1,3, побеги мирикарии длиннолистной или кору ивы - 1,8-2,3, побеги можжевельника обыкновенного или хвою сосны - 0,7-1,2, траву полыни холодной - 2,7-3,4, траву эфедры односемянной - 1,7-2,2, сушеное сырье измельчают до размера частиц 600-800 мкм, экстрагируют в экстракторе с применением вакуумно-импульсных режимов при температуре 40-45°С в течение 30-40 мин при гидромодуле 1:3-1:8, затем проводят фильтрацию, концентрирование полученного водного экстракта в концентраторе, оснащенном мешалкой, при температуре 40-45°С в течение 60-120 мин до содержания сухих веществ 60-70%, сушку густого экстракта на вакуумно-импульсном столе при температуре 40-45°С в течение 5-10 мин. Вышеописанный способ ...

Композиция растительного сырья, обладающая антиоксидантными свойствами

Изобретение относится к пищевой промышленности, а именно к композиции растительного сырья. Предложенная композиция растительного сырья представляет собой смесь, содержащую листья черники обыкновенной, листья грецкого ореха, листья смородины черной, душицу обыкновенную и чабрец, измельченную при температуре 18-20°C до размера частиц 1-2 мм, при следующем соотношении компонентов, мас.%: листья черники обыкновенной - 55-60; листья грецкого ореха - 15-20; листья смородины черной - 8-10; душица обыкновенная - 5-10; чабрец - 7-10. Заявляемая композиция растительного сырья обладает ярко выраженными антиоксидантными свойствами, может быть рекомендована для создания продуктов питания специализированного и функционального назначения. 1 табл., 3 пр.

Фитокомплекс для профилактики развития игровой зависимости (варианты)

Изобретение относится к фармацевтической промышленности, а именно к фитокомлексам для приготовления настоя для профилактики развития игровой зависимости (варианты). Фитокомплекс для приготовления настоя для профилактики развития игровой зависимости, характеризующийся тем, что содержит цветы, лист и стебель кипрея, цветы красного клевера, корень аира, траву пустырника, цветки и листья таволги, траву мяты, лист березы, лист брусники, цветы бессмертника, цветы липы, корень алтея, корень элеутерококка, корень солодки, плоды шиповника, цветы зверобоя при следующем соотношении 5:3:2:2:1:2:2:2:2:2:2:1:2:2:2 соответственно, для возрастной категории от 7 до 14 лет. Фитокомплекс для приготовления настоя для профилактики развития игровой зависимости, характеризующийся тем, что содержит цветы, лист и стебель кипрея, цветы красного клевера, корень аира, траву пустырника, цветки и листья таволги, траву мяты, лист березы, цветы бессмертника, цветы липы, корень алтея, корень элеутерококка, корень левзеи ...

Выделение грайанотоксина III из листьев рододендрона желтого

Изобретение относится к химико-фармацевтической отрасли, касается способа выделения грайанотоксина III (GTX III) из листьев рододендрона желтого. Выделение грайанотоксина III (GTX III) с помощью экстракции спиртом этиловым 95% из листьев рододендрона желтого, при котором на этапе А - получение экстракта из листьев рододендрона желтого используют сырье - листья рододендрона желтого (Rhododendron luteum Sweet, Azaleaflava Hoffmanns., Azaleapontica L., Rhododendronflavum G. Don), произрастающего на подножии Джинальского хребта в окрестностях г. Кисловодска (Российская Федерация, Ставропольский край), сырье сушат воздушно-теневым способом до остаточной влажности около 10%, измельчают до размера 1 мм, для экстракции используют точную навеску сырья около 5,0 г, объем экстрагента - 50 мл на каждой ступени, гидромодуль - 1:10, число ступеней экстракции - 2, время экстракции на каждой ступени - 2 часа с обратным холодильником, температура экстракции - 80°С, полученные извлечения объединяют, далее ...

КОМБИНАЦИЯ АКТИВНЫХ ИНГРЕДИЕНТОВ МАСЕЛ, СОДЕРЖАЩИХ W3-ЖИРНЫЕ КИСЛОТЫ, С РАСТИТЕЛЬНЫМИ ЭКСТРАКТАМИ, СОДЕРЖАЩИМИ ПОЛИФЕНОЛЫ, И ИХ ПРИМЕНЕНИЕ

... 1. Комбинация активных ингредиентов, включающая, по меньшей мере, одно масло, содержащее W3-жирные кислоты, и, по меньшей мере, один растительный экстракт, содержащий полифенолы, причем растительный экстракт, содержащий полифенолы, представляет собой экстракт из Vitis vinifera. 2. Комбинация активных ингредиентов по п.1, отличающаяся тем, что масло, содержащее W3-жирную кислоту, содержит альфа-линоленовую кислоту. 3. Комбинация активных ингредиентов по п.2, отличающаяся тем, что масло, содержащее W3-жирную кислоту, выбрано из группы, включающей перилловое масло, масло бораго, масло семян вечерней примулы, рыбий жир, льняное масло и масло семян черной смородины. 4. Комбинация активных ингредиентов по любому из пп.1-3, отличающаяся тем, что растительный экстракт, содержащий полифенолы, содержит, по меньшей мере, 15% полифенолов в расчете на вес сухого вещества. 5. Применение комбинации активных ингредиентов по любому из пп.1-4 для лечения, повышения эффективности лечения и для профилактики ...

Добавка роста для интенсивного производства сельскохозяйственной и животноводческой продукции

... 1. Добавка роста, включающая один или несколько источников сахара, один или несколько источников гидрокарбоната и один или несколько источников хлорид-ионов.2. Добавка роста по п. 1, отличающаяся тем, что источник сахара представляет собой один или несколько элементов, выбранных из группы, состоящей из глюкозы, коричневого сахара и олигосахаридов; источником гидрокарбоната является один или несколько элементов, выбранных из группы, состоящей из карбоната натрия и бикарбоната калия; и источник хлорид-ионов представляет собой один или несколько элементов, выбранных из группы, состоящей из хлорида натрия, хлорида калия, хлорида магния и хлорида кальция.3. Добавка роста по п. 2, в которой источник сахара представляет собой смесь глюкозы и коричневого сахара или только глюкозу.4. Добавка роста по п. 2, в которой источником гидрокарбоната является бикарбонат натрия.5. Добавка роста по п. 2, в которой источником хлорид-ионов является хлорид калия.6. Добавка роста по п. 2, которая дополнительно ...

Способ получения вещества, обладающего антибактериальной и противогрибковой активностью

Изобретение относится к химико-фармацевтической промышленности, а именно к способу получения вещества, обладающего антибактериальной и противогрибковой активностью. Способ получения вещества, обладающего антибактериальной и противогрибковой активностью, в котором листья толокнянки обыкновенной экстрагируют 70% этиловым спиртом, осуществляя вначале две экстракции при комнатной температуре в течение 24 ч, а затем при нагревании на кипящей водяной бане в течение 30 мин; объединенное извлечение упаривают под вакуумом, смешивают с силикагелем в соотношении исходной массы сырья и сорбента 3:1 и высушивают на воздухе; высушенный порошок наносят на слой силикагеля, сформированный в виде взвеси в хлороформе, и подвергают хроматографическому разделению с использованием смесей хлороформа и этилового спирта в градиентном режиме с последующим выделением из фракций, полученных при элюировании смесью растворителей хлороформ-спирт этиловый 95% (93:7), этилового эфира n-дигалловой кислоты - вещества с антибактериальной ...

КОМПОЗИЦИЯ И СПОСОБ ПРОФИЛАКТИКИ, СНИЖЕНИЯ, ОБЛЕГЧЕНИЯ ИЛИ ЛЕЧЕНИЯ ИДИОПАТИЧЕСКОЙ РВОТЫ

КОМПОЗИЦИИ НА ОСНОВЕ ФЛАВОНОИДОВ И СПОСОБЫ ПРИМЕНЕНИЯ

КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ СМЕСЬ ЭКСТРАКТОВ РАСТЕНИЙ ИЛИ СМЕСЬ МОЛЕКУЛ, СОДЕРЖАЩИХСЯ В УКАЗАННЫХ РАСТЕНИЯХ, И ПРИМЕНЕНИЕ ДЛЯ КОНТРОЛИРОВАНИЯ МЕТАБОЛИЗМА УГЛЕВОДОВ И/ИЛИ ЛИПИДОВ

КОМПОЗИЦИИ ДЛЯ ГИГИЕНЫ ПОЛОСТИ РТА И СПОСОБЫ

... 1. Способ лечения состояния, связанного с аномальной экспрессией ММП-13, включающий введение субъекту терапевтически эффективного количества 4-ацетамидофенил 2-изопропил-5-метилциклогексилкарбоната.2. Способ по п.1, дополнительно включающий введение субъекту терапевтически эффективного количества одного или более следующих веществ: недиализируемого материала из клюквенного экстракта, ацетил-кето-β-босвеллиевой кислоты, ресвератрола и 2-изопропил-5-метилциклогексил 2-гидроксифенилкарбамата.3. Способ по п.2, включающий введение субъекту недиализируемого материала из клюквенного экстракта.4. Способ по п.2, включающий введение субъекту ацетил-кето-(В-босвеллиевой кислоты.5. Способ по п.2, включающий введение субъекту ресвератрола.6. Способ по п.2, включающий введение субъекту 2-изопропил-5-метилциклогексил 2-гидроксифенилкарбамата.7. Способ по любому из пп.1-6, где состояние, связанное с аномальной экспрессией ММП-13 выбирают из группы, состоящей из разрушения внеклеточного матрикса, потери ...

ТРАНСДЕРМАЛЬНЫЙ ТЕРАПЕВТИЧЕСКИЙ ПРЕПАРАТ

СРЕДСТВО ДЛЯ СТИМУЛЯЦИИ ПРОДУЦИРОВАНИЯ ТРОМБОЦИТАРНОГО ФАКТОРА РОСТА ВВ И СОДЕЖАЩЕЕ ЕГО СРЕДСТВО ДЛЯ АКТИВАЦИИ ПРОДУЦИРОВАНИЯ МЕЗЕНХИМАЛЬНЫХ СТВОЛОВЫХ КЛЕТОК, СРЕДСТВО ДЛЯ СТАБИЛИЗАЦИИ СТВОЛОВЫХ КЛЕТОК И СРЕДСТВО ДЛЯ РЕГЕНЕРАЦИИ КОЖИ

... 1. Средство для стимуляции продуцирования тромбоцитарного фактора роста ВВ (PDGF-BB), содержащее в качестве активного ингредиента один или более компонентов, выбранных из числа производных брусники, производных мангустана, производных корня шлемника, инозитола и инозитолфосфата.2. Средство по п.1, содержащее инозитол и дополнительно содержащее дрожжевой экстракт.3. Средство по п.1 или 2, в котором инозитол или инозитолфосфат получают из рисовых отрубей.4. Средство для активации образования мезенхимальных стволовых клеток, содержащее средство по любому из пп.1-3.5. Средство для стабилизации стволовых клеток, содержащее средство по любому из пп.1-3.6. Средство для регенерации кожи, содержащее средство по любому из пп.1-3.

БИОЛОГИЧЕСКИ АКТИВНАЯ ДОБАВКА ДЛЯ ПРОФИЛАКТИКИ ЗАБОЛЕВАНИЙ МОЧЕВЫВОДЯЩИХ ПУТЕЙ

КОМПОЗИЦИИ И СПОСОБЫ, ИСПОЛЬЗУЕМЫЕ ДЛЯ ЛЕЧЕНИЯ СИМПТОМОВ НИЖНИХ МОЧЕВЫХ ПУТЕЙ, ДОБРОКАЧЕСТВЕННОЙ ГИПЕРПЛАЗИИ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ, ЭРЕКТИЛЬНОЙ ДИСФУНКЦИИ И ДРУГИХ ЗАБОЛЕВАНИЙ ИЛИ СИМПТОМОВ

СПОСОБ ПОЛУЧЕНИЯ ПРОАНТОЦИАНИДИНОВОГО ОЛИГОМЕРА

... 1. Композиция, содержащая в качестве главного компонента проантоцианидиновый олигомер, к концу которого присоединено вещество, содержащее флороглюциновую кольцевую структуру или резорциновую кольцевую структуру, и молекулярная масса которого уменьшена, которую получают путем нагревания растительных материалов, содержащих проантоцианидиновый полимер, или их экстрактов с веществом, содержащим флороглюциновую кольцевую структуру или резорциновую кольцевую структуру, растением, содержащим такое вещество, или его экстрактом в водном растворе кислоты. 2. Композиция, содержащая в качестве главного компонента проантоцианидиновый олигомер по п.1, в которой растение, содержащее проантоцианидиновый полимер, представляет собой по меньшей мере один вид, выбранный из группы, включающей виноград, сосну, Chamaecyparis obtuse (кипарисовик туполистный), камфарное дерево, восковник восконосный, какао, хурму обыкновенную, банан, хеномелес китайскую, яблоню, боярышник, личи, Myrica rubra (восковница красная ...

КОМПОЗИЦИИ, ВКЛЮЧАЮЩИЕ ИНГИБИТОР NFкВ И СТИМУЛЯТОР ОБРАЗОВАНИЯ ТРОПОЭЛАСТИНА

... 1. Композиция, включающая: ! ингибитор NFĸB; и ! стимулятор образования тропоэластина. ! 2. Композиция по п.1, в которой ингибитор NFĸB выбран из группы, состоящей из замещенных резорцинов, (E)-3-(4-метилфенилсульфонил)-2-пропеннитрила, тетрагидрокуркуминоидов, а также их комбинаций. ! 3. Композиция по п.1, в которой ингибитор NFĸB представляет собой замещенный резорцин. ! 4. Композиция по п.3, в которой замещенный резорцин представляет собой 4-гексилрезорцин. ! 5. Композиция по п.1, в которой стимулятор образования тропоэластина выбран из группы, состоящей из экстрактов ежевики, экстрактов скумпии, экстрактов пиретрума, экстрактов Phyllanthus niruri, а также их комбинаций. ! 6. Композиция по п.1, в которой ингибитор NFĸB и стимулятор образования тропоэластина присутствуют в концентрации в весовом соотношении от приблизительно 0,001 до приблизительно 100. ! 7. Способ лечения признаков старения кожи, включающий топическое нанесение на кожу, нуждающуюся в таком лечении, композиции, включающей ...

КОМПОЗИЦИЯ ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ НАРУШЕНИЯ МОЧЕПОЛОВОЙ СИСТЕМЫ

КОМПОЗИЦИЯ ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ КИШЕЧНЫХ ПОВРЕЖДЕНИЙ

КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ СМЕСЬ МОЛЕКУЛ, ВЫДЕЛЕННЫХ ИЗ CHRYSANTHELLUM INDICUM, CYNARA SCOLYMUS И LYCIUM BARBARUM, И ПРИМЕНЕНИЕ ДЛЯ ВОЗДЕЙСТВИЯ НА МЕТАБОЛИЗМ УГЛЕВОДОВ И/ИЛИ ЖИРОВ

КОМБИНИРОВАННЫЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЭКСТРАКТЫ ИЗ РАСТЕНИЙ И МОРСКИХ ЖИВОТНЫХ

... 1. Композиция, содержащая i) хрящевой экстракт, полученный путем ферментативного протеолитического гидролиза, или синтетические формы соединений, экстрагируемых из хряща путем ферментативного протеолитического гидролиза; ii) один или несколько гидрофильных антиоксидантов, где указанные гидрофильные антиоксиданты экстрагированы из семян винограда или представляют собой синтетические формы антиоксидантов, экстрагируемых из семян винограда; и iii) один или несколько липофильных антиоксидантов, где одним из указанных антиоксидантов является ликопен, и где указанные липофильные антиоксиданты экстрагированы из природных источников или представляют собой синтетические формы липофильных антиоксидантов, экстрагируемых из природных источников. 2. Композиция по п.1, содержащая i) хрящевой экстракт, полученный путем ферментативного протеолитического гидролиза; ii) один или несколько гидрофильных антиоксидантов, где указанные гидрофильные антиоксиданты экстрагированы из семян винограда или получены ...

Композиция для повышения качества спермы у субъекта мужского пола

Способ профилактики стрессорных реакций

Изобретение относится к фармации и медицине, а именно к способам профилактики стрессорных реакций. Способ профилактики стрессорных реакций включает применение многокомпонентного лекарственного растительного препарата, состоящего из водного настоя сбора синюхи голубой травы, зверобоя продырявленного травы, каштана конского цветков, горца щавелелистного травы в массовом соотношении 2:2:1:1 соответственно, в соотношении 1 г высушенного лекарственного растительного сырья с содержанием влаги 11 масс. % на 10 мл экстрагента - воды очищенной, настой применяют перорально в дозе 80 мг/кг массы тела из расчета по сухому остатку за 60 мин до стрессорной нагрузки. Изобретение обеспечивает эффективную профилактику стрессорных реакций. 3 ил., 3 пр.

Ein Arzneimittel zur Behandlung von Gicht und dessen Herstellungsverfahren

Die vorliegende Erfindung offenbart ein Arzneimittel zur Behandlung von Gicht und dessen Herstellungsverfahren. Das Medikament zur Behandlung von Gicht umfasst nach Gewichtsteilen Lotus Plumule 5-15, Spina Date Seed 10-15, Houttuynia cordata 13-20, Angelica sinensis 12-28 und Herba Pyrolae 5-12. Das Arzneimittel zur Behandlung von Gicht gemäß der vorliegenden Erfindung weist im Vergleich zu den Arzneimitteln des Standes der Technik andere Bestandteile auf und kann die Mängel der Arzneimittel im Stand der Technik überwinden.

Verfahren zur Gewinnung von Andromedotoxin

Verwendung von Salicylsäure und Glyzyrrhetinsäure enhaltende Zusammensetzungen zur Aknebehandlung

VERFAHREN ZUR HERSTELLUNG VON ANTHOCYANIN-ENTHALTENDEN PRODUKTEN

Process for producing a herbal composition

One or more herbs are combined with a solvent, such as water or ethanol/water mixture. The mixture is heated and any ethanol is driven off. The resulting solution is preferably cooled and separated from any solid residue and is intended for use in the preparation of a medicinal herbal composition, preferably a homeopathic composition. Plant species which may be used are Taraxacum Officinale, Agrimonia Eupatoria, Berberis Vulgaris, Silybum Marianum, Tilia Europea, Crategus Oxyacanthoides, Zanthoxylum Americanum, Arcostaphylus Uva Ursi, Juniperus Communis, Petroselinum Crispum, Zea Mays, Echinacea Angustifolia, Belladonna, Arnica Montana, Thuja Occidentalis, Astragalus Membranaceous, Angelica Sinensis or Panax Ginseng.

Homeopathic formulations useful for treating pain and/or inflammation

One of the objects of the present Invention is directed to homeopathic formulations (a) comprising tinctures and/or diluted extracts preferably subjected to potentization of at least 8 or 9 herbs selected from Bellis Perennis, Calendula Officinalis, Hamamelis Virginiana, Arnica Montana, Hypericum Perforatum, Aconitum Napellus, Ledum Palustre, Bryonia Alba and Ruta Graveolens; or (b) consisting of, as active ingredients, tinctures and/or diluted extracts subjected to potentization of 5, 6 or 7 herbs selected from Bellis Perennis, Calendula Officinalis, Hamamelis Virginiana, Arnica Montana, Hypericum Perforatum, Aconitum Napellus, Ledum Palustre, Bryonia Alba and Ruta Graveolens. The potentized homeopathics are in a base, preferably clear gel base. The homeopathic formulations are highly effective in treating or relieving pain and inflammation. The present invention is also directed to a method of treating or relieving pain and inflammation by administering any of the homeopathic formulations ...

Product

Process

STABILIZED COMPOSITIONS, THE OXYGEN-SENSITIVE CONNECTION RETINOL CONTAINING

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

ETHERI OILS COMBINATION AND THERAPEUTIC USES

NEW COMPOSITION FOR THE IMPROVEMENT OF THE SKIN CONDITION AND PROCEDURE FOR YOUR PRODUCTION

MUFFEL ZUR HERSTELLUNG VON ZAHNERSATZTEILEN

The muffle (1) has cylindrical surface area, curved surface area (33') and outer contour that is convex with two truncated cone shaped bodies (32a', 32b') of different opening angles, where a portion of the cylindrical surface area around a muffle axis (A) lies below 10 percent with respect to the contour. The contour is flattened in an upper region and a lower region of the muffle. The contour is formed in right angle to the muffle axis. A socket (36) holds the muffle in a position during pressing process. Independent claims are also included for the following: (1) a device for manufacturing a muffle (2) a method for manufacturing of dental prostheses parts.

DIÄTETI COMPOSITIONS FROM PHOSPHORYLIERTEN LIPIDEN AND YOUR USE FOR THE IMPROVEMENT OF SEHPROBLEMEN

ADHESION INHIBIERENDE VACCINIUM EXCERPT

COMPOSITIONS WITH COMBINED EXCERPTS FROM CARTILAGE FABRIC AND PLANTS

PROCEDURE FOR THE PRODUCTION OF ANTHOCYANIN CONTAINING PRODUCTS

TOPI USE FROM ETHEREAL OILS TO THE TREATMENT OF WUNDHEILUNGSSTÖRUNGEN

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

COMPOSITION FOR PREVENTION OF URINARY PASSAGE INFECTIONS

Combined preparation comprising an anthocyanin composition and an antiviral agent

The present invention is related to combined preparations comprising an anthocyanin composition and an antiviral agent for use in treating or preventing a virus infection in a subject, wherein the anthocyanin composition comprises one or more of an extract of black currants, an extract of bilberries, an extract of red grapes, and/or delphinidin 3 glucoside, wherein the virus is from the Herpesviridae family and the antiviral agent is a Herpesviridae antiviral agent, and wherein the anthocyanin composition and the antiviral agent are for simultaneous, separate or sequential use.

Cranberry seed oil extract and compositions containing components thereof

Compositions for the treatment of diseases of the oral cavity and upper respiratory tract

SOLUBLE ISOFLAVONE COMPOSITIONS

Use of at least one polyphenol for promoting eye health

The present invention relates to a method for promoting eye health by administering to a companion animal a composition comprising at least one polyphenol selected from the group consisting of rosemary, rosemary extract, coffeic acid, coffee extract, turmeric extract, cucurmin, blueberry extract, grapeseed extract, rosemarinic acid, tea extract, and mixtures thereof.

Treatment and prevention mucositis by anthocyanidin derivatives

Compositions enriched in phenolic compounds and methods for producing the same

Compositions for the treatment of peripheral ulcers of various origins

The present invention relates to compositions containing a combination of a cell proliferation-stimulating agent with vasokinetic properties and an antimicrobial, antifungal and antiviral agent with an anti-inflammatory/analgesic, which is useful in the treatment of peripheral ulcers of various origins, such as diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores and the associated skin infections. Said combination could be presented as formulations for topical or systemic use.

A composition for buccal absorption of nicotine for the purpose of smoking cessation

Methods and compositions for helping the body resist the effects of the aging process

ACTIVE SUBSTANCE MIXTURES OF EXTRACTS OF THE GENUS VACCINIUM AND CAROTENE COMPOUNDS

USE OF COMPOSITIONS COMPRISING BENZOYL PEROXIDE AND GLYCYRRHETINIC ACID FOR THE TREATMENT OF ACNE

ANTIALLERGIC AGENT AND ANTIINFLAMMATORY AGENT

Composition and method for preventing, reducing, alleviating or treating idiopathic vomiting

The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HT3a and/or NK-1 receptor for preventing or treating idiopathic vomiting.

Composition and method for preventing, reducing, alleviating or treating idiopathic vomiting

The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HT3a and/or NK-1 receptor for preventing or treating idiopathic vomiting.

Composition containing a mixture of plant extracts or a mixture of molecules contained in said plants, and use for controlling glucide and/or lipid metabolism

The invention relates to a composition containing at least one mixture of molecules obtained from at least ...

Coating method and materials

A system consisting of a component coating a particulate scaffold is able to transfer the coating to an exposed surface in order to yield beneficial effects. The system is useful for many applications, including the treatment of individuals suffering from a disease, cancer, an ailment, an infection, a toxin, or other syndrome, as well as for numerous non-treatment purposes requiring the coating of exposed surfaces.

Urogenital and intestinal compositions

A pharmaceutical composition for stopping opium addiction and preparation thereof

FRUIT AND/OR VEGETABLE DERIVED COMPOSITION

There is provided a process for making a composition suitable for topical application comprising the steps of: a)heating at least one fruit and/or vegetable pulp to up to a temperature in the range of about 40~C to 100~C; b) mixing between 1 and 40% w/w of a mild base with the heated fruit and/or vegetable pulp. There is also provided a fruit and/or vegetable derived composition suitable for topical application prepared by the above process. There is further provided a fruit and/or vegetable derived composition comprising at least one fruit and/or vegetable-derived pulp and a mild base, said composition having a pH in the range of about 7.5 to about 9.5.

BERRY OILS AND PRODUCTS

ANTIBACTERIAL FOOD COMPOSITION

La présente invention concerne une composition alimentaire antibactérienne comprenant un extrait de Propolis et un extrait de cranberry Vaccinium macrocarpon.

PROCESS OF EXTRACTING PROCYANIDINS BY ALKALINE HYDROLYSIS

A process of extracting procyanidins by alkaline hydrolysis. In particular, a procyanidin-containing material, pomace or residue is treated with an alkali, such as sodium or potassium hydroxide, for a predetermined amount of time and at a predetermined temperature to release procyanidins bound to polysaccharides and/or proteins of the cell wall or depolymerize polymeric procyanidins. After the procyanidins are released by alkaline hydrolysis, the extracts are acidified to obtain a pH level where the procyanidins do not degrade. The process of extracting procyanidins may be utilized to estimate the total amount of bound procyanidins in a plant material, enhance the bioavailability of beneficial procyanidins monomers and/or to treat the residue remaining after conventional solvent extraction for increased procyanidin extraction.

COMBINED PREPARATION COMPRISING AN ANTHOCYANIN COMPOSITION AND AN ANTIVIRAL AGENT

The present invention is related to combined preparations comprising an anthocyanin composition and an antiviral agent for use in treating or preventing a virus infection in a subject, wherein the anthocyanin composition comprises one or more of an extract of black currants, an extract of bilberries, an extract of red grapes, and/or delphinidin 3 glucoside, wherein the virus is from the Herpesviridae family and the antiviral agent is a Herpesviridae antiviral agent, and wherein the anthocyanin composition and the antiviral agent are for simultaneous, separate or sequential use.

METHOD FOR PURIFYING A RED FRUIT EXTRACT CONTAINING ANTHOCYANOSIDES

COMPOSITION FOR IMPROVING IMMUNE SYSTEM HEALTH

COMPOSITIONS CONTAINING AN EXTRACT OF A PRIMULA DENTICULATA AND USE THEREOF

The present invention features composition comprising an extract of a primula denticulata and the use thereof for treating acne and reducing the appearance of oil or pores on the skin, hair and scalp.

COMPOSITIONS AND METHOD FOR TREATING AND PREVENTING COMPLICATIONS OF OBESITY

Provided herein are compositions and methods for treating, preventing, and reducing the risk of obesity and related diseases and conditions. In particular, provided herein is a composition comprising a dry powder of fruits and vegetables and uses thereof.

COMPOSITIONS AND METHODS OF TREATMENT FOR MVID AND RELATED DISEASES

A composition, comprising: a. a retinoid; b. a polyphenol; and c. a zinc salt, calcium salt, selenium salt, bismuth salt, or a combination thereof.

DEACIDIFIED CRANBERRY JUICE AND METHOD FOR THE PRODUCTION THEREOF

L'invention concerne un jus désacidifié, ainsi qu'un procédé de désacidification d'un jus de canneberge à désacidifier qui est élué sur un lit d'une résine échangeuse d'anions faibles à un taux (BV/h) tel que le jus de canneberge désacidifié en sortied'élution présente un pH= p Ka1 (acide malique) < pH < pKa (acide benzoique). L'invention a aussi pour objet une composition alimentaire qui comprend ce jus de fruit désacidifié.

ANXIOLYTIC MARCGRAVIACEAE COMPOSITIONS CONTAINING BETULINIC ACID, BETULINIC ACID DERIVATIVES, AND METHODS

Pharmaceutical compositions for preventing or treating anxiety, comprising betulinic acid or derivatives thereof are provided. Methods for preventing or treating anxiety with betulinic acid or derivatives thereof are also provided. The invention further provides betulinic-acid containing preparations of plants of the family Marcgraviaceae having anxiolytic activity and methods for making such extracts and using them to prevent or treat anxiety in a subject.

HONEY BEE MITE DISRUPTIVE COMPOUNDS AND METHODS OF APPLICATION

This disclosure describes compounds that affect the olfactory responses of the honey bee mite (Varroa destructor) and methods of use thereof. The compounds do not kill Varroa destructor, and are therefore unlikely to generate Varroa destructor resistance, compared to an acaricide. The compounds can work in conjunction with other mite control approaches, such as a bottom board excluder and sticky board control devices, and can enhance the performance of other forms of mite control while decreasing disadvantages associated therewith.

COLD-WARM PLASTER COMPRISING VANILLYL BUTYL ETHER AND MENTHOL DISPERSED IN A HYDROGEL

A composition for topical application characterized in that it includes, in a hydrogel base, vanillyl butyl ether and menthol. The composition described herein produces an ordered development of cold and warm sensations, obtaining effects that are particularly useful in the treatment of painful disorders of neurological and/ or muscular origin. The composition has further moisturizing and soothing effects that concur to an effect that is also curative, i.e., not simply symptomatic, of rheumatic and muscular pain, trauma and bruises. The composition is compatible with each administration form, being preferably and advantageously formulated as a plaster.

COMPOSITION CONTAINING A MIXTURE OF PLANT EXTRACTS OR A MIXTURE OF MOLECULES CONTAINED IN SAID PLANTS, AND USE FOR CONTROLLING GLUCIDE AND/OR LIPID METABOLISM

L'objet de l'invention est une composition comprenant au moins un mélange de molécules obtenues au moins à partir de : - Chrysanthellum indicum, et - Cynara scolymus, et - Vaccinium myrtillus, ledit mélange de molécules comprenant également de la pipérine. Cette composition est particulièrement utile comme produit de nutrition ou produit de santé pour prévenir et/ou lutter contre les dérèglements du métabolisme glucidique et/ou lipidique chez l'Homme ou l'animal.

ORAL COMPOSITIONS CONTAINING BOTANICAL EXTRACTS

The disclosure provides oral compositions having at least two botanical active ingredients derived from plants. The oral composition also includes an orally acceptable vehicle to deliver an effective amount of the at least two active ingredients in vivo. The botanical active ingredients provide particularly efficacious antimicrobial (antibacterial, antiviral, and/or antifungal), antioxidant, anti-inflammatory, anti-ageing, and or healing properties to the oral compositions.

COMPOSITIONS COMPRISING AN NFKB-INHIBITOR AND A TROPOELASTIN PROMOTER

The present invention relates to a composition comprising an NF.kappa.B-inhibitor and a tropoelastin promoter, and methods of treating signs of skin aging using said compositions.

FORMULATIONS FOR THE TREATMENT OF DISORDERS OF THE UPPER RESPIRATORY TRACT

The present invention relates to formulations containing extracts of Vaccinium myrtillus or other species rich in anthocyanosides, Punica granatum, Echinacea, and optionally Krameria triandra. Said formulations are useful in the treatment of disorders of the mouth and its adnexa, the throat and respiratory tract, and in the treatment of influenza.

ANTI-FATIGUE COMPOSITION

The present invention provides a food supplement composition for preventing or reducing fatigue, for increasing recovery from fatigue or for enhancing endurance or recovery to exercise, which contains collagen hydrolysate, blueberry extract, polyphenol, and licorice extract. In addition, the food supplement composition of the invention can be prepared as solid-state modes to e taken, such as tablets, pellets and powder. Moreover, these can be prepared as various beverages such as so-colled health drinks and sports drinks or as food items for fatigue-recovering and prevention, or endurance enhancer to exercises and stress.

PHOSPHORYLATED LIPID BASED DIETETIC COMPOSITIONS AND THEIR USE IN THE IMPROVEMENT OF VISION PROBLEMS

L'invention se rapporte à de nouvelles compositions riches en lipides phosphorés d'origine naturelle. Elle a pour objet des compositions diététiques dont les constituants principaux sont: a) un triglycéride de formule dans laquelle X et Y, identiques ou différents, représentent le reste acyle d'un acide gras polyinsaturé ayant de 18 à 24 atomes de Carbone. R est de l'hydrogène ou un carboxyle et Z est un radical aminé, primaire, secondaire, tertiaire ou quaternaire et b) de l'huile de poisson des mers froides riches en DHA, en EPA et en Vitamine A en association ou en mélange avec un diluant, un agent support et/ou un agent liant et un complément alimentaire. Ces compositions sont utiles pour l'amélioration des troubles de la vision ...

Verfahren zur Herstellung von Salzen in Wasser unlöslicher Triterpensäuren

Cure de soins cosmétiques pour la peau.

СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШУМА В УШАХ

В изобретении описано применение экстракта черники для приготовления терапевтической композиции, предназначенной для приема внутрь при лечении и/или профилактике шума в ушах.

СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШУМА В УШАХ

В заявке описано применение экстракта черники для приготовления терапевтической композиции, предназначенной для приема внутрь при лечении и/или профилактике шума в ушах.

VEGETABLE EXTRACT COMPOSITIONS AS ANTIMICROBIAL AND/OR ANTIBIOPLENOChNYI AGENT

Anti-inflammatory dissolvable film

Provided, among other things, is a slowly dissolvable film comprising: herbal bioactive agent(s); and polymer(s), dissolvable in the aggregate, wherein the film becomes adhesive as it is placed against a mucosal surface and begins to absorb moisture therefrom.

Antibacterial Food Composition

The present invention relates to an antibacterial food composition comprising a Propolis extract and a Vaccinium macrocarpon cranberry extract.

Stabilized anthocyanin compositions

The invention describes stabile anthocyanin compositions, methods to prepare such compositions and also methods of use of such compositions to treat various afflictions. The present invention describes unique compositions of an anthocyanin and a stabilizing compound such that the combination of the two components provides that the anthocyanin does not readily undergo degradation, such as oxidation, pH instability, etc.

Composition for treatment of aesthenopia

This is to provide a novel medicine and a food and a drink composition for treating aesthenopia excellent in improved effect of aesthenopia. The composition for the treatment of aesthenopia comprises chondroitin sulfate or a salt thereof.

BATHING COMPOSITION AND METHOD FOR PREPARING SAME

The present invention relates to a composition for bath additives characterized in that the composition is obtained by a process comprising subjecting herbal materials comprising 10˜25% by weight of , 10˜20% by weight of , 5˜15% by weight of , 1˜20% by weight of , 1˜15% by weight of , 1˜15% by weight of , 1˜15% by weight of -, 1˜10% by weight of and 1˜10% by weight of , based on the total dry weight of the above herb materials, to liquid phase fermentation with which is anaerobic, to obtain a culture, separating sludge from the resulting culture, drying, sterilizing and pulverizing the culture to give a pulverized sludge, and a process for preparing the same. 1Zizania latifolia,Artemisia capillaries,Houttuynia cordata,Saururus chinensis,Leonurus sibiricus,Angelica gigas,Coix lachrymajobi,Plantago asiaticaRhododendron brachycarpumBacillus subtilis. A composition for bath additives obtained by subjecting medicinal herb materials comprising 10˜25% by weight of 10˜20% by weight of 5˜15% by weight of 1˜20% by weight of 1˜15% by weight of 1˜15% by weight of 1˜15% by weight of -1˜10% by weight of and 1˜10% by weight of , based on the total dry weight of the above herb materials , to liquid phase fermentation with which is anaerobic , to obtain a culture , separating sludge from the resulting culture , drying , sterilizing and pulverizing the culture to give a pulverized sludge.2. The composition for bath additives as claimed in wherein the liquid phase fermentation is performed at a temperature of 30˜40° C. for 50˜100 days.3Achillea sibirica,Rumex crispus, andLithospermum erythrorhizon.. The composition for bath additives as claimed in wherein the above medicinal herb materials further comprise 1˜10% by weight of Saliconia herbacea claim 1 , 7˜17% by weight of 5˜15% by weight of 1˜10% by weight of4. A composition for bath additives characterized in that the composition is obtained by a process comprising:{'i': Zizania latifolia,', 'Artemisia capillaries,', 'Houttuynia ...

TRANSMUCOSAL COMPOSITION CONTAINING ANTHOCYANINS FOR ALLEVIATING A VISUAL DISCOMFORT

The present invention relates to a composition comprising a natural extract containing anthocyanins and an agent for enhancing vigilance, and to a method for alleviating visual discomfort related to or caused by oxidative stress comprising administering via transmucosal route the composition of the invention, said composition being in a form adapted to transmucosal administration, said form preferably being a chewing gum, an orodispersible/orodisintegrating tablet or film or a buccal spray. 1. A composition comprising a natural extract containing anthocyanins , an agent for enhancing vigilance , and optionally at least one of lutein , zeaxanthin , meso-zeaxanthin and asthaxanthin; said composition being in an unitary dosage form adapted to transmucosal administration , said unitary dosage form preferably being a chewing gum , an orodispersible/orodisintegrating tablet or film or a buccal spray.2. A composition according to claim 1 , wherein said composition is a nutraceutical composition claim 1 , a food or dietary supplement claim 1 , a functional food or a pharmaceutical composition.3. A composition according to or claim 1 , wherein said transmucosal administration is a buccal administration.4. A composition according to anyone of to claim 1 , wherein said agent for enhancing vigilance is at least one of caffeine claim 1 , taurin and vitamin C claim 1 , preferably caffeine.5. A composition according to anyone of to claim 1 , wherein said unitary dosage form comprises an amount of natural extract containing anthocyanins ranging from 0.1 to 200 mg.6Vaccinium MyrtillusRubusRubus occidentalisVaccinium corymbosumVaccinium macrocarponVaccinium oxycoccusRubus idaeusFragaria X ananassaPrunus virginianaViburnum trilobumAmelanchier alnifoliaShepherdia argenteaRubus articusRibes nigrumRubus chamaemorusEmpetrum nigrum, Empetrum hermaphroditumSambucusRibes uvacrispaVaccinium vitisidaeaRubus loganobaccusSorbusHippophae rhamnoidesPunica granatumLycium barbarumGarcinia ...

PHYTONUTRIENT COMPOSITIONS AND METHODS TO PROTECT AGAINST RADICAL MEDIATED CELLULAR AND DNA DAMAGE

Phytonutrient based compositions and methods of using the same for preventing, reducing, or treating genetic damage induced by environmental toxins are disclosed. 1Acacia nilotica. A phytonutrient composition for preventing , reducing , or treating genetic damage induced by environmental agents , wherein said composition comprises therapeutically effective amounts of two or more compounds selected from the group consisting of extract , artichoke extract , blueberry extract , catechins , chlorogenic acid , cinnamon , ellagic acid , grape seed extract , hesperidin , Momodica extract , prune extract , rosemary extract , and watercress extract and said composition is in a dosage form suitable for oral administration.2. The composition according to claim 1 , wherein said composition provides per dosage form:{'i': 'Acacia nilotica', 'a. from 0.5 mg to 10 mg of extract;'}b. from 0.5 mg to 10 mg of artichoke extract;c. from 1 mg to 25 mg of blueberry extract;d. from 2.5 mg to 25 mg of catechins;e. from 25 mg to 75 mg of chlorogenic acid;f. from 0.5 mg to 10 mg of cinnamon;g. from 10 mg to 100 mg of ellagic acid;h. from 2.5 mg to 50 mg of grape seed extract;i. from 15 mg to 120 mg of hesperidin;j. from 0.5 mg to 10 mg of Momodica extract;k. from 0.5 mg to 10 mg of prune extract;l. from 0.5 mg to 10 mg of rosemary extract; andm. from 0.5 mg to 10 mg of watercress extract.3Acacia nilotica. A method for preventing claim 1 , reducing claim 1 , or treating genetic damage induced by environmental agents claim 1 , wherein said method comprises administering a composition comprising therapeutically effective amounts of two or more compounds selected from the group consisting of extract claim 1 , artichoke extract claim 1 , blueberry extract claim 1 , catechins claim 1 , chlorogenic acid claim 1 , cinnamon claim 1 , ellagic acid claim 1 , grape seed extract claim 1 , hesperidin claim 1 , Momodica extract claim 1 , prune extract claim 1 , rosemary extract claim 1 , and watercress ...

NUTRIGENOMIC METHODS TO OVERCOME CARBOHYDRATE BINGEING AND OVEREATING

This invention concerns Reward Deficiency Syndrome (RDS) and obesity, and the role of catecholaminergic pathways in aberrant substance-seeking behavior, in particular cravings for carbohydrates. Also described are new nutrigenomic formulas having unique combinations of ingredients having a generalized anti-craving effect are, which can inhibit carbohydrate bingeing, inducing significant healthy fat loss and relapse prevention, as well genetic testing for certain polymorphisms correlated with RDS behaviors. 1. A composition comprising an effective amount of:(a) at least one substance that inhibits the enzymatic destruction of an opioid (opiate) neuropeptide (preferably an amino acid, peptide, or structural analogue or derivative thereof);(b) a neurotransmitter synthesis-promoting amount of at least one neurotransmitter precursor, preferably a dopamine precursor such as L-Tyr, L-Phe, or L-Dopa, a serotonin precursor (e.g., L-Trp, and 5-hydroxytryptophan), and/or a gamma amino butyric acid (GABA) precursor, for example, L-glutamine, 1-glutamic acid, and L-glutamate (or GABA itself);(c) a tryptophan concentration-enhancing amount of any chromium salt (for example chromium picolinate or chromium nicotinate);(d) a neurotransmitter synthesis-promoting amount of at least one neurotransmitter synthesis promoting substance or catabolic inhibitor selected from the group consisting of rhodiola and huperzine; and(e) at least one of the following:(e)(1) Rhodiola;(e)(2) Passionflower (incarnata);(e)(3) vitamin B6;(e)(4) vitamin B 1;(e)(5) carnitine;(e)(6) Rhododendron;(e)(7) (−)-Mineral salts of (−)Hyroxycitric acid;(e)(8) Gymnema sylvestre; and(e)(9) calcium.3. A method for treating or preventing obesity claim 1 , comprising administering to a patient suffering or recovering from or predisposed to develop obesity an amount of composition according to effective to treat or prevent obesity.4. A method according to claim 1 , further comprising before administration of said ...

Two-Phase Preparation And Use Thereof For The Treatment Of Herpes

The invention relates to a novel two-phase preparation for use as a food supplement, dietary substance, and/or medicament. The medical use thereof for helping the immune system fight against viral diseases, especially herpes, is particularly preferred. Said preparation may have two different phases which may be used in a chronologically staggered manner, mutually blocking agents being in different phases and mutually boosting agents being in the same phase. 1. A two-phase preparation for use in a chronologically staggered manner comprising(a) a phase (A) comprising, in addition to water-soluble vitamins and/or the corresponding pro-vitamins, plant constituents and optionally minerals and/or trace elements, in a first unit dose form(b) a phase (B) comprising, in addition to fat-soluble vitamins and/or the corresponding pro-vitamins, plant constituents and optionally minerals and/or trace elements, in a second unit dose form,characterized in that phase (A) preferably contains grape seed extract and/or cranberry juice powder as plant constituents and that phase (B) preferably contains green tea extract and/or pomegranate extract as plant constituents.2. The two-phase preparation according to claim 1 , wherein{'sub': 6', '2', '1', '12, 'phase (A) comprises D-pantothenic acid (preferably as calcium D-pantothenate), niacin (preferably as nicotinamide), vitamin B(preferably as pyridoxine HCl), riboflavin (vitamin B), vitamin B(preferably as thiamine mononitrate), vitamin B(preferably cyanocobalamin), and/or folic acid, as water-soluble vitamins'}and/or{'sub': '3', 'phase (B) comprises vitamin E, vitamin D, and/or beta-carotene, as fat-soluble vitamins.'}3. The two-phase preparation according to claim 1 , whereinphase (A) comprises 40 mg-160 mg of grape seed extract, preferably 60 mg-120 mg of grape seed extract, and/or 20 mg-80 mg of cranberry juice powder, preferably 20 mg-80 mg of cranberry juice powder as plant constituentsand/orphase (B) comprises 5 mg-160 mg of green ...

Food recipes for nourishing, maintaining and cultivating a variety of stem cells and a method for manufacturing the same

A food recipes for nourishing, maintaining and cultivating a variety of stem cells, each unit of the food recipes includes grape skin/polygonum cuspidatum root extracts; pseudo-ginseng extracts; cooked polygonum multiflorum thunb extracts; salvia miltiorrhiza bunge extracts; blueberry extracts; bitter melon extracts; soybean extracts; ginseng extracts; rhodiola extracts; yam extracts; licorice extracts; kudzu extracts; brown algae extracts; green algae extracts; szechuan lovage rhizome extracts, Green tea extracts; apple extracts; leek seed extracts; wolfberry extracts; marigold extracts; ganoderma lucidum extracts; caterpillar fungus extracts; agaricus blazei extracts; cistanche deserticola extracts; mushroom extracts; beer yeast; flaxseed oil powder; and vitamin.

VACCINIUM SPECIES COMPOSITIONS

This invention relates to novel compositions comprising as an active ingredient one or more berries, leaves, roots, and/or root barks obtained from one or more plant species of the genus , wherein said plant(s) is/are grown under the following conditions: (a). Subject to one or more uninterrupted photoperiod(s) of at least about 18 hours to 24 hours per day for about 60 days during flowering and fruit setting; and; (b). Subject to one or more uninterrupted photoperiod(s) of at least about 15 hours per day for about 30 days during fruit ripening and maturity. More particularly, said plant(s) is/are optionally grown at least 7 days past maturity. Further, the compositions of the inventive subject matter optionally may include an additional element comprising an oil from species. Further, said compositions may be employed to treat a variety of diseases, disorders, and conditions, as described herein. 1Vaccinium,. A method for treating or managing a disorder in an animal , which comprises administering to said animal an effective amount of a composition comprising one or more berries , obtained from one or more plant species of the genus i. subject to one or more uninterrupted photoperiods of at least about 18 hours to 24 hours per day for about 60 days during flowering and fruit setting; and', 'ii. subject to one or more uninterrupted photoperiods of at least about 15 hours per day for about 30 days during fruit ripening and maturity;, 'wherein said one or more plant species, harvested at least 7 days past peak fruit ripeness, have grown under the following conditionswherein said disorder is a urinary tract infection, tuberculosis, heart disease, diarrhea, cardiovascular disease, Alzheimer's disease, or vascular dementia; wherein said composition comprises, at least in part, a metabolite produced by one or more stress-related phenylpropanoid pathways; and wherein said administering is accomplished orally, parenterally, by inhalation spray, rectally, nasally, buccally, ...

Formulations for the treatment of disorders of the upper respiratory tract

The present invention relates to formulations containing extracts of Vaccinium myrtillus or other species rich in anthocyanosides, Punica granatum, Echinacea , and optionally Krameria triandra . Said formulations are useful in the treatment of disorders of the mouth and its adnexa, the throat and respiratory tract, and in the treatment of influenza.

Compositions for improving mental performance

The present invention provides formulas for producing compositions for the structural/functional nutritional support for those who struggle with poor focus, concentration and/or memory. In addition, the present invention provides compositions comprising nutritional/botanical factors helpful to those who subjectively experience transient mental fatigue or poor cognitive function. The compositions of this invention consist primarily of the following ingredients B-complex vitamins, antioxidants, minerals, phosphatidyl serine (PS), choline, dimenthyl-aminoethanol (DMAE), docosahexaenoic acid (DHA), L-pyroglutamic acid, as well as herbal extracts from Bacopa monniera, Vinca minor , and Huperzia serrata . The present invention also relates to the administration of these compounds to alleviate mental fatigue or poor cognitive function.

PHYTONUTRIENT COMPOSITIONS AND METHODS OF USE

Phytonutrient based compositions and methods of using the same for preventing, reducing, or treating genetic damage induced by environmental toxins are disclosed. Additionally, said compositions and methods are used to reduce oxidized low density lipoproteins (OxLDL), myeloperoxidase (MPO), and plasminogen activator inhibitor-1 (PAI-1). 1Acacia niloticaMomodica. Use of a composition for simultaneously reducing serum OxLDL , MPO , and PAI-1 levels in a subject in need thereof , wherein said use comprises administering a composition comprising therapeutically effective amounts of two or more compounds or extracts selected from the group consisting of extract , artichoke extract , blueberry extract , catechins , chlorogenic acid , cinnamon , ellagic acid , grape seed extract , hesperidin , extract , prune extract , rosemary extract , and watercress extract and said composition is in a dosage form suitable for oral administration wherein said dosage form provides:{'i': 'Acacia nilotica', 'a. from 0.5 mg to 10 mg of extract;'}b. from 0.5 mg to 10 mg of artichoke extract;c. from 1 mg to 25 mg of blueberry extract;d. from 2.5 mg to 25 mg of catechins;e. from 25 mg to 75 mg of chlorogenic acid;f. from 0.5 mg to 10 mg of cinnamon;g. from 10 mg to 100 mg of ellagic acid;h. from 2.5 mg to 50 mg of grape seed extract;i. from 15 mg to 120 mg of hesperidin;{'i': 'Momodica', 'j. from 0.5 mg to 10 mg of extract;'}k. from 0.5 mg to 10 mg of prune extract;l. from 0.5 mg to 10 mg of rosemary extract; andm. from 0.5 mg to 10 mg of watercress extract.2Acacia niloticaMomodica. The use according to claim 1 , wherein the composition provides three or more compounds or extracts selected from the group consisting of extract claim 1 , artichoke extract claim 1 , blueberry extract claim 1 , catechins claim 1 , chlorogenic acid claim 1 , cinnamon claim 1 , ellagic acid claim 1 , grape seed extract claim 1 , hesperidin claim 1 , extract claim 1 , prune extract claim 1 , rosemary extract claim 1 ...

Anti-fatigue composition

The present invention relates to a food supplement composition for reducing fatigue, and/or improving recovery and resistance to fatigue. The composition comprised of collagen hydrolysate, blueberry extract and liquorice extract.

METHODS TO ISOLATE ANTI-MICROBIALS FROM FRUIT OR SEED EXTRACTS

The invention provides a method of isolating one or more compounds present in fruit juice or seed extracts that have anti-microbial activity. 1. A method to isolate compounds having anti-microbial activity , comprising:a) providing a fruit or fruit seed extract dissolved or suspended in water, alcohol or in a water alcohol mixture;b) separating the extract on a C8 column into a plurality of fractions; andc) isolating at least one fraction that is at least 80% by weight of a compound or a plurality of compounds with anti-microbial activity.2. The method of wherein the at least one fraction comprises about 1 mg to about 100 mg of the compound.3. The method of further comprising subjecting the at least one fraction to rotavapping at 40° C.4. The method of further comprising lyophilizing the at least one fraction.5. The method of wherein the extract is a filtered extract.6. The method of wherein prior to separation on the C8 column claim 1 , the extract was subjected to separation on a C18 solid phase extraction column and ion exchange chromatography column.7. The method of wherein high pressure liquid chromatography is employed to separate the extract.8. The method of wherein the at least one fraction has at least about 95% of the compound claim 1 ,9. The method of wherein the fruit is a cranberry.10. The method of wherein the seed extract is a cranberry seed extract.11. The method of wherein a plurality of chromatographic separation techniques are employed to isolate the fraction having the substantially pure compound.12111. The method of claim wherein the separation includes solid phase exchange claim 1 , ion exchange chromatography claim 1 , high performance liquid chromatography or simulated moving bed chromatography.13. The method of wherein at least one compound is a flavonol claim 1 , proanthocyanin claim 1 , diterpenoid epoxide claim 1 , or phenylpropanoid.14. An antimicrobial compound isolated by:a) separating a fruit or fruit seed extract dissolved or ...

METHODS AND COMPOSITIONS FOR TREATMENT OF URINIARY TRACT INFECTIONS

A composition for treatment of urinary tract infection derived primarily from pomegranate and cranberry fruit components is disclosed. The composition may be derived from juices, concentrates, liquid extracts, or powdered extracts, e.g. dehydrated pomegranate juice, of pomegranate and cranberry fruits. The concentration of each of the component (i.e. pomegranate product and cranberry product) in the composition is set such as to achieve optimum synergistic effects by increasing urinary tract anti-adhesion activity. 1. A composition for treatment of urinary tract infection comprising:a pomegranate-derived component comprising hydrolyzable tannins; anda cranberry-derived component, wherein said pomegranate-derived component and said cranberry-derived component are combined in a proportion of polyphenolic content to form a composition with a synergistic effect of increasing urinary tract anti-adhesion activity.2. The composition of claim 1 , wherein said proportion of polyphenolic content is approximately 85% of said pomegranate-derived component and approximately 15% of said cranberry-derived component.3. The composition of claim 2 , wherein said pomegranate-derived component is pomegranate juice concentrate and said cranberry-derived component is cranberry juice concentrate.4. The composition of claim 1 , wherein said pomegranate-derived component is pomegranate juice concentrate and said cranberry-derived component is cranberry juice concentrate.5. The composition of claim 1 , wherein said pomegranate-derived component is dehydrated pomegranate juice and said cranberry-derived component is dehydrated cranberry juice.6. The composition of claim 1 , wherein said pomegranate-derived component is powdered pomegranate extract and said cranberry-derived component is powdered cranberry extract.7. The composition of claim 1 , wherein said proportion of polyphenolic content is approximately 80% of said pomegranate-derived component and approximately 20% of said cranberry- ...

METHOD OF EXTRACTING ACTIVE MOLECULES FROM NATURAL RESINS AND USE THEREOF

The present invention relates to a method of extracting active molecules from natural resins and/or essential oils. In particular, the present invention relates to a method of extracting active molecules selected from the group comprising terpenes, flavonoids, anthocyanins and catechins. Moreover, the present invention relates to an extract, preferably in liquid form, obtained with said method. Finally, the present invention relates to the use of said extract containing the active molecules selected from the group comprising terpenes, flavonoids, anthocyanins and catechins for the preparation of a food composition or supplement or a pharmaceutical composition. 1. A method of extracting active molecules from a vegetable substrate , said method comprising contacting said substrate with an extraction liquid , said extraction liquid comprising:an extraction gas in the gaseous state at a temperature of 23° C. and pressure of 1 atmosphere, andan extraction solvent comprising acetic acid.2. The method according to claim 1 , wherein the active molecules extracted from the vegetable substrate are selected from the group comprising terpenes claim 1 , flavonoids claim 1 , anthocyans and catechins.3. The method according to claim 1 , wherein the vegetable substrate is selected from the group comprising natural resins claim 1 , fossil resins claim 1 , seed claim 1 , barks claim 1 , leaves claim 1 , algae claim 1 , essential oils claim 1 , roots claim 1 , vegetables and fruit.4. The method according to claim 1 , wherein said extraction gas is selected from the group comprising helium claim 1 , neon claim 1 , argon claim 1 , krypton claim 1 , xenon claim 1 , carbon dioxide claim 1 , nitrogen claim 1 , oxygen or mixtures thereof.5. The method according to claim 4 , wherein said extraction gas is selected from the group comprising argon claim 4 , nitrogen claim 4 , carbon dioxide claim 4 , an argon and nitrogen mixture claim 4 , an argon and carbon dioxide mixture claim 4 , a ...

Annatto Extract Compositions Including Tocotrienols and Tocopherols and Methods of Use

Compositions and methods of use of annatto extracts [350-450 Dalton molecular weight fraction] including tocotrienols and tocopherols with an appropriate spectrum. This spectrum includes but not limited to low alpha tocopherol, high delta- and gamma-tocols, and mixtures with other extracts [350-450 Dalton molecular weight fraction] like palm and rice and/or nutrients. 1. A composition comprising a mixture of an annatto extract with tocotrienol and a natural extract , where the ratio of delta-tocotrienol to gamma-tocotrienol is from 1:25 to 25:1.2. The composition of claim 1 , where the standardized tocopherols is from less than 50% to less than 1%.3. The composition of claim 1 , where the natural extract is selected from the group consisting of soy claim 1 , corn claim 1 , rice bran claim 1 , palm claim 1 , olive claim 1 , wheat germ claim 1 , oat bran claim 1 , sunflower seed claim 1 , cottonseed claim 1 , cranberry seed claim 1 , and litchi seed.4. The composition of claim 2 , where the tocopherol is alpha-T1.5. The composition of claim 1 , where the annatto extract and the natural extract produce an appropriate spectrum.6. The composition of claim 5 , where more than 50% of the tocotrienols are delta-T3 and gamma-T3.7. The composition of claim 5 , where more than 50% of the tocotrienols are delta-T3.8. The composition of claim 5 , where the composition is tocopherol-free.9. The composition of claim 1 , where the tocotrienol is a C5 unsubstituted tocotrienol and the composition comprises more than 60% C5 unsubstituted tocotrienols claim 1 , and less than 15% tocopherols.10. The composition of claim 1 , wherein the tocotrienol activates PPARs.11. The composition of claim 10 , where the tocotrienol further down regulates SREBP transcription factors.12. The composition of claim 1 , where the tocotrienol decreases blood levels of triglyceride.13. The composition of claim 12 , where the decrease in the blood level of the triglyceride has an effect selected from the ...

ANTACID FORMULATIONS AND ASSOCIATED METHODS

The present invention provides antacid compositions and associated methods. In one aspect for example, an antacid composition suitable for delivery to a subject for reducing a digestive condition includes an effective amount of at least one citrate compound, an effective amount of blueberry product, and an effective amount of fruit extract including a member selected from the group consisting of pomegranate extract, bilberry extract, elderberry extract, blueberry extract, and combinations thereof. 1. An antacid composition suitable for delivery to a subject for reducing a digestive condition , comprising:an effective amount of at least one citrate compound;an effective amount of a blueberry product selected from the group consisting of blueberry fiber, blueberry fruit, and combinations thereof; andan effective amount of fruit extract including a member selected from the group consisting of pomegranate extract, bilberry extract, elderberry extract, blueberry extract, and combinations thereof.2. The composition of claim 1 , wherein the citrate compound is selected from the group consisting of magnesium citrate claim 1 , calcium citrate claim 1 , sodium citrate claim 1 , potassium citrate claim 1 , and combinations thereof.3. The composition of claim 1 , wherein the citrate compound includes magnesium citrate and calcium citrate.4. The composition of claim 1 , wherein the fruit extract includes at least two members selected from the group consisting of pomegranate extract claim 1 , bilberry extract claim 1 , elderberry extract claim 1 , blueberry extract claim 1 , and combinations thereof.5. The composition of claim 1 , wherein the fruit extract includes pomegranate extract claim 1 , bilberry extract claim 1 , and elderberry extract.6. The composition of claim 5 , wherein the fruit extract includes blueberry extract.7. The composition of claim 1 , wherein the blueberry product is blueberry fiber and the composition is formulated as a member selected from the group ...

METHODS AND COMPOSITIONS FOR IDENTIFYING, PRODUCING AND USING PLANT-DERIVED PRODUCTS FOR MODULATING CELL FUNCTION AND AGING

Provided herein are methods of culturing cells in vitro in order to exploit the biochemical production ability of the cells to make metabolites that are evaluated and harvested for their biological effects. Also provided are systems for evaluating extracts from such cultured cells to characterize their biological activity(s), particularly with regard to impact on health, wellbeing, longevity, DNA maintenance, mitochondrial health and/or biogenesis, and so forth. Biologically active extracts, components thereof, and compositions (such as cosmetic or pharmaceutical preparations) made comprising such, are also provided. 1. A method for identifying an agent that modulates lifespan of a cell , tissue , organ or organism , the method comprising:contacting the cell, tissue, organ or organism with a non-animal extract or non-animal-derived composition;assessing the influence of the extract or composition on lifespan of the cell, tissue, organ or organism; andselecting the extract or composition as one that modulates lifespan if there is a measurable influence on lifespan of the cell, tissue, organ or organism contacted with the extract or composition in comparison to a corresponding cell, tissue, organ or organism not contacted with the extract or composition, thereby identifying the agent as one that modulates lifespan.2. The method of claim 1 , wherein the extract or composition is prepared from or derived from plant claim 1 , fungus claim 1 , algae claim 1 , or bacterium cells.3. The method of claim 2 , wherein the plant claim 2 , fungus claim 2 , algae claim 2 , or bacterium cells are genetically modified.4. The method of claim 2 , wherein the plant claim 2 , fungus claim 2 , algae claim 2 , or bacterium cells are subjected to a mechanical claim 2 , chemical claim 2 , or biological elicitation event prior to preparation of the extract or composition.5. The method of claim 4 , wherein the elicitation event comprises one or more of contact with or exposure to: specific ...

COMPOSITIONS AND METHOD FOR TREATING AND PREVENTING MALNUTRITION

Provided herein are compositions and methods for treating, preventing, and reversing malnutrition. In particular, provided herein are compositions and methods for facilitating cognitive repair and preventing obesity (e.g. in children). 193.-. (canceled)94. A composition for the treatment and prevention of malnutrition , comprising:a) at least 20 mg of a plurality of flavonoids, wherein at least a portion of the flavonoids cross the blood-brain barrier, wherein at least one of said flavonoids is catechin or epicatechin; b) at least 0.1 g of omega-3 fatty acids, wherein said omega-3 fatty acids comprise EPA and DHA;c) at least 1 mg caffeine; d) a plurality of micronutrients selected from the group consisting of iron, phosphorous, zinc, thiamine, riboflavin, niacin, vitamin B6, folate, vitamin, B12, pantothenic acid, biotin, choline, chromium, copper, manganese, seleniusm, molybdenum, iodine, vitamin A, calcium, potassium, magnesium, vitamin E, vitamin C, a carotenoid, vitamin D, and vitamin K; and e) a sufficient amount of energy comprising 11-35% of calories from protein, 10-50% of calories from carbohydrates, and 30-60% of calories from fat.95. The composition of claim 94 , wherein said composition comprises 20-2000 mg of flavonoids.96. The composition of claim 94 , wherein said composition comprises at least 200 mg of flavonoids.97. The composition of claim 94 , wherein said composition comprises 200-500 mg of catechin and/or epicatechin.98. The composition of claim 94 , wherein said catechin and/or epicatechin are in or obtained from cocoa and/or green tea.99. The composition claim 94 , wherein said flavonoids are derived from a plant or plant component selected from the group consisting of cocoa claim 94 , green tea claim 94 , black tea claim 94 , tea extracts claim 94 , quercetin claim 94 , green vegetables claim 94 , spinach claim 94 , moringa claim 94 , matcha claim 94 , kaempferol claim 94 , kale claim 94 , tomato claim 94 , acai berry claim 94 , blueberry ...

HOMEOPATHIC THERAPEUTIC METHOD AND COMPOSITIONS

Methods of producing a Hydrophilic Homeopathic Aqueous Substance Active (HASA)-gel matrix, include the steps of: (a) combining a homeopathic compound and an uninhibited aqueous composition to produce a HASA; (b) combining the HASA with at least one hydrophilic gelling agent; and (c) thereafter, forming the hydrophilic HASA-gel matrix by use of at least one of a thickening agent, a crosslinking agent, or a polymerization agent. 130-. (canceled)31. A method of producing a hydrophilic homeopathic gel matrix , the method comprising the steps of: (a) combining diluted aqueous homeopathic composition comprising a homeopathic compound and uninhibited water at a homeopathic compound-to-water ratio of no more than 0.000001 with at least one hydrophilic gelling agent to produce a solution comprising the hydrophilic gelling agent and the diluted aqueous homeopathic composition; and (b) forming the hydrophilic homeopathic gel matrix by crosslinking or polymerizing the solution comprising the hydrophilic gelling agent with the diluted aqueous homeopathic composition.32. The method of claim 31 , wherein the diluted aqueous homeopathic composition comprises the homeopathic compound and uninhibited water at a ratio of no more than 0.00000001.33. The method of claim 31 , wherein the diluted aqueous homeopathic composition comprises the homeopathic compound and uninhibited water at a ratio of no more than 0.00000000001.34. The method of claim 31 , wherein the hydrophilic homeopathic gel matrix comprises at least about 50% by weight of the diluted aqueous homeopathic composition.35. The method of claim 31 , wherein the hydrophilic homeopathic gel matrix comprises at least about 60% by weight of the diluted aqueous homeopathic composition.36. The method of claim 31 , wherein the hydrophilic homeopathic gel matrix comprises at least about 80% by weight of the diluted aqueous homeopathic composition.37. The method of claim 31 , wherein the hydrophilic homeopathic gel matrix comprises ...

PREPARATION FOR PROTECTING AGAINST EXTRINSIC AND INTRINSIC SKIN AGING

Disclosed is a cosmetic or dermatological preparation which comprises one or more extracts of (purple saxifrage) and/or one or more extracts of (alpine snowbell). The use of these extracts to combat extrinsic and intrinsic skin aging is likewise described. 1Soldanella alpina. A cosmetic or dermatological preparation , wherein the preparation is suitable for topical application to human skin and for cosmetic and/or dermatological use , is present as at least one of a dispersion , gel , aqueous and/or alcoholic solution , serum , oil , tincture , ointment , salve or wipe impregnation media and comprises , based on a total weight of the preparation , from 0.0001% to 15% by weight of (i) one or more extracts of , as well as one or more components selected from fats , oils , waxes , moisturizing and/or humectant substances , alcohols , polyols , polymers , electrolytes , organic solvents , silicones , foam stabilizers , substances for preventing foaming , dyes , coloring pigments , thickeners.2Saxifraga oppositifolia.. The preparation of claim 1 , wherein the preparation further comprises from 0.0001% to 15% by weight of (ii) one or more extracts of3. The preparation of claim 2 , wherein the preparation comprises from 0.0001% to 1% by weight of (i) and/or from 0.0001% to 1% by weight (ii).4. The preparation of claim 1 , wherein (i) comprises at least one water-soluble extract obtained by hydro-alcoholic extraction of plant material.5. The preparation of claim 4 , wherein the plant material comprises plant leaves and/or plant stems.6. The preparation of claim 1 , wherein (i) comprises at least one oil-soluble extract obtained by supercritical fluid extraction of plant material.7. The preparation of claim 6 , wherein the plant material comprises plant leaves and/or plant stems.8. The preparation of claim 1 , in which all of the one or more extracts (i) are water-soluble or all of the one or more extracts (i) are oil-soluble.9Chlamydocapsa. The preparation of claim 1 , ...

COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING A URINARY TRACT INFECTION

A composition comprising D-Mannose, Extract and Cranberry is disclosed. The disclosed composition, is useful in treating and preventing a microbial infection and induced red blood cells agglutination. 1Phellodendron. A composition comprising D-Mannose and Extract , wherein said D-Mannose weight is from 3.5% to 85% of the total weight of said composition.2. The composition of claim 1 , wherein said composition further comprises a Cranberry.3. The composition of claim 1 , wherein said composition further comprises Methylsulfonylmethane (MSM).4. The composition of claim 1 , wherein said composition further comprises Cinnamon.5Phellodendron. The composition of claim 2 , wherein weight ratio of D-Mannose to Extract to Cranberry is from 4:4:1 to 4:1:2.6. The composition of claim 1 , wherein said composition is an oral composition.7. The composition of claim 6 , wherein said oral composition is selected from the group consisting tablet claim 6 , capsule claim 6 , solution claim 6 , powder claim 6 , suspension claim 6 , syrup or beverage.8. A method of treating a subject afflicted with a urinary tract microbial infection claim 1 , comprising the step of administering to said subject a therapeutically effective amount of a composition of claim 1 , thereby treating a subject afflicted with a urinary tract microbial infection.9. The method of claim 8 , wherein said treating a subject afflicted with a urinary tract microbial infection is inhibiting the attachment of a microorganism to an epithelial cell.10. The method of claim 8 , further comprising administering to said subject a urinary tract antibiotic.11. A method of preventing a urinary tract microbial infection in a subject claim 1 , comprising the step of administering to a subject a therapeutically effective amount of a composition of claim 1 , thereby preventing a urinary tract microbial infection in a subject.12. The method of claim 11 , wherein said preventing comprises daily supplementation of said composition.13. A ...

INCORPORATION OF CULTURED BILBERRY CELLS IN COSMETICS, DIETARY SUPPLEMENTS, AND/OR FUNCTIONAL FOODS

Compositions include cultured bilberry cells or extracts thereof mixed with a cosmetic component or a food component to yield cosmetics, dietary supplements, and/or functional foods. The cultured bilberry cells or extracts can have high levels of polyphenols with little or no anthocyanins. The polyphenol fraction from the cultured bilberry cells is unique compared to the polyphenol fraction from the tissues of a traditional bilberry plant. The cultured cells have high levels of natural flavonols, flavan-3-ols and procyanidins, but are notably lacking in anthocyanins and chlorogenic acid. 1. A biologically compatible composition , comprising ,cultured bilberry cells including at least 10% on a dry weight basis of polyphenolic compounds and less than 1.0% dry weight anthocyanin compounds; andone or more biologically compatible components including dermatological components or food components, the biologically compatible components mixed with the cultured bilberry cells to yield the biologically compatible composition.2. The composition of claim 1 , wherein the polyphenolic compounds include at least 50% of one or more anti-oxidant and/or anti-inflammatory compounds selected from the group consisting of (−)-epicatechin claim 1 , (+)-catechin claim 1 , procyanidins claim 1 , quercetin claim 1 , isoquercetin (quercetin 3-O-glucoside) claim 1 , quercetin 3-O-arabinose claim 1 , naringenin claim 1 , or combinations of these.3. The composition of claim 1 , wherein the cultured cells have less than 1% chlorogenic acid.4. The composition of claim 1 , wherein the one or more biologically compatible components are dermatological components and the combination of the dermatological components and the cultured cells yield a dermatological suspension claim 1 , emulsion claim 1 , paste claim 1 , gel claim 1 , cream claim 1 , lotion claim 1 , powder claim 1 , soap claim 1 , surfactant-containing cleanser claim 1 , oil claim 1 , powder foundation claim 1 , emulsion foundation claim 1 ...

MULTI-NUTRIENT SUPPLEMENT COMPOSITION AND USES THEREOF

Various embodiments of the invention relate to compositions comprising vitamins, minerals and trace elements, antioxidants, amino acids, probiotics, and other components and methods for using such compositions to treat or prevent diseases associated with oxidative stress, including cardiovascular disease. 1. (canceled)2. A method of delaying or preventing the onset of a disease and/or condition associated with oxidative stress comprising administering to a human subject a therapeutically effective amount of a composition comprising:(i) vitamin A, vitamin B1 vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, calcium source, potassium source, magnesium source, phosphate source, iodine, copper source, chromium source, manganese source, molybdenum source, selenium source, zinc source, lycopene, one or more carotenoids, one or more flavonoids, biotin, inositol, choline, one or more amino acids,(ii) a probiotic composition comprising the powder of one or more dried fruits and pollen extract or Terminalia arjuna or an extract thereof,(iii) fish oil, and(iv) one or more pharmaceutically acceptable excipients;wherein the composition delays or prevents the onset of a disease and/or condition associated with oxidative stress.3. The method of claim 2 , wherein the composition comprises vitamin A (0.01-10 mg) claim 2 , vitamin B(1-50 mg) claim 2 , vitamin B(1-50 mg) claim 2 , vitamin B(1-100 mg) claim 2 , vitamin B(1-100 mg) claim 2 , vitamin B(0.5-50 mg) claim 2 , vitamin B(0.0001-2 mg) claim 2 , vitamin C (0.1-1000 mg) claim 2 , vitamin D (0.0001-1 mg) claim 2 , vitamin E (1-500 mg) claim 2 , vitamin K (0.001-5 mg) claim 2 , folic acid (0.0001-5 mg) claim 2 , calcium source (0.1-1000 mg) claim 2 , potassium source (0.1-1000 mg) claim 2 , magnesium source (0.1-1000 mg) claim 2 , phosphate source (1-500 mg) iodine source (0.0001-5 mg) claim 2 , copper source (0.0001-10 mg) claim 2 , chromium source (0.0001-10 rug) ...

OPHTHALMIC COMPOSITIONS

The present invention relates to a sterile ophthalmic composition comprising castor oil and a medium chain triglyceride, to its use in medicine, in particular for the treatment and/or prevention of an ocular disease selected from the group consisting of dry eye, conjunctivitis, dermatitis, blepharitis, entropion, floppy eyelid syndrome, thyroid ophthalmopathy, pterygium, conjunctivochalasis, epithelial damage induced by preservatives, epithelial or anterior chamber damage induced by ocular surgery, limbal cell deficiency, corneal ulcers induced by physical or chemical agents, keratitis, episcleritis and uveitis. 1. Sterile ophthalmic composition comprising:a) an oily phase comprising castor oil and a medium chain triglyceride,b) one or more surfactants andc) an aqueous phase wherein the composition has a pH from 5.0 to 9.0.2. Composition according to wherein it does not comprise any one of the following active ingredients: mesopram claim 1 , sotalol and cyclosporine A.3. Composition according to claim 1 , wherein the castor oil and the medium chain triglyceride are in a ratio by weight of from 50:1 to 1:50 claim 1 , preferably from 10:1 to 1:10 claim 1 , more preferably from 1.5:1 to 1:1.5 claim 1 , more preferably 1:1.4. Composition according to claim 1 , wherein the total amount of castor oil and medium chain triglyceride is from 0.05 to 70 wt % with respect to the total weight of the composition.5. Composition according to claim 1 , wherein the medium chain triglyceride is caprylic/capric acid triglyceride.6. Composition according to claim 1 , further comprising one or more oils other than the castor oil and the medium chain triglyceride claim 1 , preferably wherein the one or more oil other than the castor oil and the medium chain triglyceride is selected from the group consisting of ethyl oleate claim 1 , isopropyl myristate claim 1 , isopropyl palmitate claim 1 , isopropyl isostearate claim 1 , isostearyl isostearate claim 1 , myristyl lactate claim 1 , ...

Compositions and methods for treating diarrheal diseases

Provided is a composition for the treatment of diarrheal disease, comprising a polyphenol-rich extract of a mixture of 80-20% by weight of blueberry or bilberry from Vaccinium cyanococcus spp., Vaccinium myrtillis spp., or both; and 20-80% by weight of sloe berry from Prunus spinosa spp. Other compositions, and methods of making and using the compositions for the treatment of diarrheal disease are disclosed.

COMPOSITION FOR RELIEVING STRESS AND ENHANCING IMMUNITY AND PREPARATION METHOD THEREOF

The invention belongs to the technical field of health food and particularly relates to a composition for relieving stress and enhancing immunity and a preparation method thereof. The composition for relieving stress and enhancing immunity is calculated in parts by weight, 100-300 parts of a radix curcuma extract, 100-250 parts of a sea cucumber extract, 100-250 parts of a chlorella extract, 50-150 parts of a cranberry extract, 100-300 parts of a ginseng extract, 80-150 parts of a coconut oil extract and 100-200 parts of a palm oil extract. The composition can significantly enhance the body's immunity, relieve mental stress and improve the level of human health. In addition, the composition of the present invention is suitable for long-term use and has a small adverse reaction. 1. A composition for relieving stress and enhancing immunity , characterized in , the composition for relieving stress and enhancing immunity is calculated in parts by weight , 100-300 parts of a turmeric extract , 100-250 parts of a sea cucumber extract , 100-250 parts of a chlorella extract , 50-150 parts of a cranberry extract , 100-300 parts of a ginseng extract , 80-150 parts of a coconut oil extract , and 100-200 parts of a palm oil extract.2. The composition for relieving stress and enhancing immunity according to claim 1 , characterized in claim 1 , the composition for relieving stress and enhancing immunity is calculated in parts by weight claim 1 , further comprising 50-100 parts of lecithin and 50-80 parts of 5-hydroxytryptophan.3. The composition for relieving stress and enhancing immunity according to claim 1 , characterized in claim 1 , the composition for relieving stress and enhancing immunity is calculated in parts by weight claim 1 , 150-250 parts of a turmeric extract claim 1 , 100-200 parts of a sea cucumber extract claim 1 , 150-200 parts of a chlorella extract claim 1 , 80-100 parts of a cranberry extract claim 1 , 150-250 parts of a ginseng extract claim 1 , 100-150 ...

ADDITIVE AND/OR SYNERGISTIC COMBINATIONS OF METFORMIN WITH NUTRACEUTICALS FOR THE PREVENTION, INHIBITION AND TREATMENT OF SARS-COV-2 AND ASSOCIATED COVID-19

Disclosed are compositions of matter, treatments and protocols useful for prevention of SARS-CoV-2 infection, as well as inhibition of viral propagation and acceleration of viral cure. In some embodiments the invention teaches the administration of a therapeutic combination of ingredients comprising of metformin, pterostilbene, nigella sativa, sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal at risk of infection with SARS-CoV-2. In another embodiment, the invention teaches administration of said therapeutic combination to a mammal infected with said SARS-CoV-2. In some embodiments dosage of said therapeutic combination is based on inflammatory and/or immunological parameters observed in patients with COVID-19. 1. A method of inhibiting infection with SARS-CoV-2 , suppressing proliferation of SARS-CoV-2 and inducing resolution of SARS-CoV-2 comprising administration of a therapeutic combination comprising: a) Green Tea and/or extract thereof; b) Blueberry and/or extract thereof; c) Nigella Sativa and/or extract thereof; d) broccoli and/or extract thereof and e) metformin2. The method of claim 1 , wherein said green tea extract is epigallocatechin-3-gallate or an analogue thereof.3. The method of claim 1 , wherein said blueberry extract is pterostilebene or an analogue thereof.4. The method of claim 1 , wherein said Nigella Sativa extract is thymoquinone or an analogue thereof.5. The method of claim 1 , wherein said broccoli extract is sulforaphane or an analogue thereof.6. The method of claim 1 , wherein said therapeutic combination is administered at a dosage and frequency sufficient to inhibit viral establishment into the host.7. The method of claim 6 , wherein inhibition of viral establishment into the host is accomplished byenhancement of natural killer cell activity.8. The method of claim 6 , wherein inhibition of viral establishment into the host is accomplished byenhancement of interferon production.9. The method of claim 1 , wherein said ...

CAPSULE-CONTAINING POUCHED PRODUCT FOR ORAL USE

A pouched product adapted for release of a releasable component therefrom is provided herein. The pouched product can include a water-permeable fabric pouch formed so as to define a cavity therein, and a composition contained within the cavity of the water-permeable fabric pouch, the composition including one or more releasable components that are released from the composition under mouth conditions and that are capable of movement through the water-permeable fabric pouch. The composition includes nicotine and at least one particulate non-tobacco material. The pouched product also includes at least one capsule contained within the cavity of the water-permeable fabric pouch, the capsule having a capsule wall surrounding an inner payload comprising at least one botanical. 1. A pouched product adapted for oral use , comprising:a water-permeable fabric pouch formed so as to define a cavity therein;a composition contained within the cavity of the water-permeable fabric pouch, the composition comprising one or more releasable components that are released from the composition under mouth conditions and that are capable of movement through the water-permeable fabric pouch, the composition comprising nicotine and at least one particulate non-tobacco material; andat least one capsule contained within the cavity of the water-permeable fabric pouch, the at least one capsule having a capsule wall surrounding an inner payload comprising at least one botanical.2. The pouched product of claim 1 , wherein the capsule wall comprises a material configured to be broken by shear forces.3. The pouched product of claim 1 , wherein the at least one particulate non-tobacco material comprises microcrystalline cellulose.4. The pouched product of claim 1 , wherein the nicotine is synthetic nicotine.5. The pouched product of claim 4 , wherein the synthetic nicotine is in the form of S(−)-nicotine or a racemic mixture composed predominantly of S(−)-nicotine.6. The pouched product of claim 1 , ...

Anti-Inflammatory Botanical Extract

A botanical extract that exhibits anti-inflammatory activity, wherein the botanical extract is at least an extract from the leaf of 1. A composition comprising:{'i': 'Vaccinium macrocarpon,', 'the botanical extract of the leaf of'}wherein the botanical extract is present in the composition in an amount of about 50.0 μg/mL to about 500.0 μg/mL,wherein the botanical extract is free of anthocyanins, and{'i': 'Vaccinium macrocarpon,', 'wherein the botanical extract has a flavonoid content of at least about twenty times greater than that of an extract of the fruit of'}wherein the composition exhibits anti-inflammatory activity.2. The composition according to claim 1 , wherein the composition inhibits COX-1 activity.3. The composition according to claim 1 , wherein the composition inhibits COX-2 activity.4. The composition according to claim 1 , wherein the composition inhibits 5-LOX activity.5. The composition according to claim 1 , wherein the composition inhibits COX-1 activity claim 1 , COX-2 activity claim 1 , and 5-LOX activity.6. The composition according to further comprising a pharmaceutically acceptable carrier.7. The composition according to wherein the composition is a dietary supplement.8. The composition according to wherein the composition is a topical composition. The present application is a divisional application of U.S. patent application Ser. No. 16/561,596, filed 5 Sep. 2019, which claims the benefit of U.S. Patent Application No. 62/728,125, filed 7 Sep. 2018, the disclosure of which is incorporated herein in its entirety by reference.Field of the Invention The present invention generally relates to a botanical extract that exhibits anti-inflammatory activity, namely, cranberry () leaves, and compositions comprising such an extract.Arachidonic acid and its metabolites are important mediators of inflammation. Arachidonic acid (‘AA’) is a component of membrane phospholipids where the rate-limiting step in the formation of its metabolites depends on its ...

NEUROPROTECTION AND NEUROREGENERATION BY PTEROSTILBENE AND COMPOSITIONS THEREOF

Disclosed are means, compositions of matter, and protocols useful for neuroprotection and neuroregeneration. In one embodiment the invention provides administration of pterostilbene alone or in combination with other ingredients to induce neuroprotection and/or neuroregeneration. The invention teaches protection/regeneration in conditions associated with neurological inflammation and/or other congenital or acquired neurodegenerative diseases. 1. A method of protecting from damage and/or regenerating a neurological tissue comprising administration of pterostilbene , and/or Green Tea and/or extract thereof , and/or Blueberry and/or extract thereof; c) Nigella Sativa and/or extract thereof; and d) broccoli and/or extract thereof.2. The method of claim 1 , wherein said neurological protection is inhibition of neuronal apoptosis.3. The method of claim 1 , wherein said neurological protection is inhibition of neuronal dysfunction.4. The method of claim 1 , wherein said neurological protection is inhibition of neuronal excitotoxicity.5. The method of claim 1 , wherein said neurological protection is inhibition of neuronal oxidative stress.6. The method of claim 1 , wherein said neurological protection is upregulation of bcl-2.7. The method of claim 1 , wherein said neurological protection is downregulation of fas ligand.8. The method of claim 1 , wherein said neurological protection is downregulation of fas.9. The method of claim 1 , wherein said regeneration of said neurological tissue comprises stimulation of axonal re-connections.10. The method of claim 1 , wherein said regeneration of said neurological tissue comprises stimulation of proliferation of neural progenitor cells.11. The method of claim 10 , wherein said neural progenitor cells are endogenous.12. The method of claim 10 , wherein said neural progenitor cells are exogenous.13. The method of claim 11 , wherein said endogenous neural progenitor cells are originating from the subventricular zone.14. The method of ...

SYSTEM AND METHOD OF COMPLEMENTARY DAY/NIGHT CHILDREN'S SKIN CREAM COMPOSITIONS

A new skin care system includes day and night skin cream compositions comprising nutrients and antioxidants for use by children between six months and eighteen years of age. The day skin cream composition provides protection from UV radiation and the night skin cream composition contains no sun protection ingredients and elevated levels of nutrients and antioxidants. A child-friendly bottle for each composition can be used by young children without difficulty. A fragrance included in each composition is popular with children, and the bottle for the day composition has graphics indicating day-time use and the bottle for the night composition has graphics indicating night-time use. The day composition is applied topically each day to the face after tooth-brushing, and the night composition is applied topically to the face each night after tooth-brushing. 1. A skin care system , comprising:day and night skin cream compositions comprising nutrients and antioxidants that are safe to be used by children between six months and eighteen years of age;wherein the day skin cream composition provides protection from UV radiation;and wherein the night skin cream composition contains no sun protection ingredients and higher levels of water and nutrients and antioxidants and lower levels of skin conditioning agents than in the day skin cream composition;wherein both compositions comprise water, capric triglyceride, shea butter, sunflower seed oil, glycerin, borage seed oil, cetearyl alcohol and glucoside, glyceryl stearate, xanthan gum, DHA and benzyl alcohol, fragrance, Vitamin E, aloe vera inner leaf gel, and blueberry extract;wherein the day composition further comprises zinc oxide and titanium dioxide and has an SPF of at least 20; andwherein the nighttime composition further comprises stearic acid, niacinamide, sweet almond oil, raspberry ketone, cucumber melon extract, acai berry extract and pomegranate extract.2. The skin care system of claim 1 , wherein the night skin ...

FORMULATION FOR ALLEVIATION OF KIDNEY STONE AND GALLSTONE SYMPTOMS AND METHOD OF TREATMENT

A nutraceutical formula and food-based medicinal composition is provided comprising homeopathic ingredients in combination with traditional herbal and nutraceutical ingredients for relieving the symptoms associated with presence or formation of kidney stones and gallstones. The formulation includes ingredients balanced in a synergistic manner to elicit complementary effects which both reduce the symptoms of kidney stones and gallstones and provide the potential to eliminate their occurrence in the body and prevent future recurrence. Methods of making and using core medicinal formulations and food-based compositions are also described.

COMPOSITIONS FOR TREATING OBESITY

Embodiments of the invention are directed to compositions containing cannabinoids and bioenhancers for treating obesity, eating disorders, metabolic disorders, and other body weight related diseases and disorders, and methods for treating obesity, eating disorders, metabolic disorders, and other body weight related diseases and disorders by administering compositions containing cannabinoid and a bioenhancer. 1. A composition comprising a cannabinoid , bioenhancer , and a pharmaceutically acceptable carrier , excipient , diluent , reagent , or combinations thereof.2. The composition of claim 1 , wherein the cannabinoid has a concentration of about 20% (w/w) to about 1% (w/w) cannabinoid claim 1 , relative to a total amount of the composition.3. The composition of claim 1 , wherein the cannabinoid is selected from the group consisting of cannabidiol claim 1 , cannabidiol isomer claim 1 , cannabidiol analog claim 1 , or combinations thereof.4. The composition of claim 1 , wherein the bioenhancer has a concentration of about 0.05% (w/w) to about 20% (w/w) claim 1 , relative to a total weight of the composition.5. The composition of claim 1 , wherein the bioenhancer is a cyclic peptide.6. The composition of claim 1 , wherein the bioenhancer is piperidine or a piperidine derivative.7. The composition of claim 1 , further comprising an appetite suppressant.8. The composition of claim 7 , wherein the appetite suppressant has a concentration of about 0.05% (w/w) to about 20% (w/w) claim 7 , relative to the total amount of the composition.9. The composition of claim 7 , wherein the appetite suppressant is an extract selected from the group consisting of grapes claim 7 , pine claim 7 , cocoa claim 7 , tamarind claim 7 , tomato claim 7 , peanut claim 7 , almond claim 7 , apple claim 7 , cranberry and blueberry.10. A method for reducing the weight of a mammal comprising administering to the mammal a composition comprising a cannabinoid claim 7 , bioenhancer claim 7 , and a ...

Compositions Containing Enriched Natural Crocin and/or Crocetin, and Their Therapeutic or Nutraceutical Uses

The invention relates to unique compositions containing enriched and purified natural crocin and/or crocetin for prevention and/or treatment of cancers and other conditions and diseases. Compositions comprise mainly enriched or purified natural crocin or crocetin or combination of both and possible other active phytochemicals. A composition is used as functional food, drink, dietary supplement, or therapeutic dosage to a human orally or through other appropriate way (parenteral, percutaneous, rectal, mucosal, intranasal or topical administration). A method of natural crocin and crocetin enriching and purification is revealed. 1. A nutraceutical or therapeutic composition comprising:(1) in percentage by 1-80%, of at least one of crocin and crocetin, wherein crocin and/or crocetin is extracted, enriched and/or purified from natural source to a purity of at least 65%; and{'i': ginseng', 'astragalus', 'rhodiola', 'stevia, '(2) at least one additional ingredient selected from the following: quercetin, resveratrol, pterostilbene, curcumin, theaflavin, theaflavin-3,3′-digallate, theaflavin-3-gallate, theaflavin-3′-gallate, anthocyanidins, anthocyanins, catechin, epicatechin, gallocatechin, epigallocatechin, epicatechin gallate, gallocatechin gallate, epigallocatechin gallate, nobiletin, tangeretin, α-lipoic acid, L-carnitine, carnosine, astragaloside, cycloastragenol, lutein, β-lycopene, zeaxanthin, rosarin, β-rosasterol, rosavin, rosin, dihydromyricetin, chlorogenic acid, glycyrrhizic acid ammonium salt, rebaudioside A, green tea extract, black tea extract, bilberry extract, extract, grape extract, grape seed extract, epimedium extract, schisandra extract, extract, extract, citrus fruit extract, orange extract, lemon extract, licorice extract, artichoke leaf extract, gotu kola extract, or extract, wherein the selected at least one additional ingredient, in percentage by weight, 1-40%, wherein the composition having the ingredient in amount, individually and/or combined, ...

Supplement Composition and Methods of Use

The present disclosure provides a supplement composition for an animal comprising: cranberry oil in the volume range of 10-30%, 20-40% soybean oil in the volume range of and fish oil in the volume range of 30-70%. 1. A supplement composition comprising: cranberry oil in the volume range of 10-30% , 20-40% soybean oil in the volume range of and fish oil in the volume range of 30-70%.2. The composition of comprising cranberry oil in the volume range of 20-30%.3. The composition of comprising 20% cranberry oil.4. The composition of further comprising 25% soybean oil and 55% fish oil.5. The composition of wherein the cranberry oil is extracted from cranberry seeds.6. The composition of wherein the cranberry oil is extracted from the cranberry seeds via cold expeller extraction.7. An equine nutritional supplement consisting essentially of: cranberry oil in the volume range of 10-30% claim 5 , 20-40% soybean oil in the volume range of and fish oil in the volume range of 30-70%.8. The composition of consisting essentially of cranberry oil in the volume range of 20-30%.9. The composition of consisting essentially of 20% cranberry oil.10. The composition of further consisting essentially of 25% soybean oil and 55% fish oil.11. The composition of wherein the cranberry oil is extracted from cranberry seeds.12. The composition of wherein the cranberry oil is extracted from the cranberry seeds via cold expeller extraction.13. An animal nutritional supplement consisting of: cranberry oil in the volume range of 10-30% claim 12 , 20-40% soybean oil in the volume range of and fish oil in the volume range of 30-70%.14. The composition of consisting of cranberry oil in the volume range of 20-30%.15. The composition of consisting of 20% cranberry oil.16. The composition of further consisting of 25% soybean oil and 55% fish oil.17. The composition of wherein the cranberry oil is extracted from cranberry seeds.18. The composition of wherein the cranberry oil is extracted from the ...

PHYTOCOMPLEXES EXHIBITING MULTIPLE, SYNERGISTIC ANTIOXIDANT ACTIVITIES USEFUL IN FOODS, DIETARY SUPPLEMENTS, COSMETICS AND PHARMACEUTICAL PREPARATIONS

Compositions comprising apple, grape, green tea, and olive extracts are presented herein. This synergistic formulations apple, grape, green tea, and olive extract are in amounts that provide a greater antioxidant activity or protein kinase modulating activity than provided by an equivalent amount of any one extract or a sum of the extracts. Further presented are methods of regulating oxidative stress, disease-associated protein kinase activity, and enhancing the therapeutic effect of a primary therapeutic agent. Also presented are methods of making an activity enhancing composition for regulating oxidative stress, disease-associated protein kinase activity, and enhancing the therapeutic effect of a primary therapeutic agent. 1. An oxidative stress modulating composition comprising:a combination of apple, grape, green tea, and olive extract in amounts that provide a greater antioxidant activity than provided by an equivalent amount of any one extract or a sum of the extracts.2Malus pumila.. The composition of claim 1 , wherein the apple extract comprises an extract of a species3Vitis vinifera.. The composition of claim 1 , wherein the grape extract comprises an extract of a species4Camellia sinensis.. The composition of claim 1 , wherein the green tea extract comprises an extract of leaves of a species5Olea europea europaea.. The composition of claim 1 , wherein the olive extract comprises an extract of a subspecies6. The composition of claim 1 , wherein at least one of the extracts in the composition is present in a different amount than an amount of at least one of another extract.7. The composition of claim 1 , wherein the apple claim 1 , grape claim 1 , green tea claim 1 , and olive extracts are present in the composition at a weight ratio of about 1:1:1:1.8. The composition of claim 1 , wherein the apple claim 1 , grape claim 1 , green tea claim 1 , and olive extracts are present in the composition at a weight ratio of about 6:1:3:19. The composition of claim 1 ...

MERRIMIA TRIDENTATA COMPOSITIONS

A composition including a powder or extract of Merremia Tridentata mixed with a liposome carrier. The liposome carrier may be a lotion, cream or suspension. The composition may be used to treat Osteophytes of the spine, feet, hands, and knees. 1. A composition comprising Merremia Tridentata , the composition further comprising a topical carrier for an application to a surface of an animal body , wherein the carrier comprises a liposome.2. The composition of claim 1 , wherein the Merremia Tridentata is in the form of at least one of an extract and a powder.3. The composition of claim 2 , wherein the extract is an oil extract.4. The composition of claim 3 , wherein the oil extract is Prasarini oil.5. The composition of claim 4 , wherein the Prasarini oil is at a concentration in the carrier of at least about 1.25 g/ml to up to about 6.35 g/ml.6. The composition of claim 4 , wherein the Prasarini oil is further mixed with Mahanarayana oil.7. The composition of claim 6 , wherein the Parasarini oil and the Maharayana oil are at a ratio of at least about 3:1 and up to about 1:3.8. The composition of claim 4 , wherein 100 ml of the Prasarini oil comprises: Prasarini 7.778 g; Sahachara 7.778 g; Sathavari 7.78 g; Bala 7.78 g; Atmagupta 7.78 g; Asvagandha 7.78 g; Ketaki 7.78 g; Tagara 0.039g; Madana 0.039 g; Kushtha 0.039 g; Kesara 0.039 g; Mustaka 0.039 g; Tvak 0.039 g; Rasna 0.039 g; Saindhva 0.039 g; Pippalavu 0.039 g; Mamsi 0.039 g; Manjistha 0.039 g; Meda 0.039 g; Mahameda 0.039 g; Jivaka 0.039 g; Rsabha 0.039 g; Satapusha 0.039 g; Vyaghranakha 0.039 g; Sunti 0.039 g; Devahva 0.039 g; Kakoli 0.039 g; Ksirakakoli 0.039 g; Vaca 0.039 g; Bhallataka 0.039 g; Paya 10 ml; Masu 10 ml; Sukta 10 ml; and Mamsasarasa 10 ml.9. The composition of claim 1 , further comprising Turmeric.10. The composition of claim 1 , further comprising clove oil claim 1 , wintergreen oil claim 1 , and Boswelia oil.11. The composition of claim 1 , wherein the topical carrier is in the form of a cream ...

Prevention of Neuroinflammation associated Memory Loss Using Nutraceutical Compositions

Disclosed are means, methods, and therapeutic compositions for prevention of memory loss during situations of neuroinflammation. In one embodiment the invention teaches administration of the therapeutic combination of ingredients comprising of pterostilbene, , sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal suffering from inflammation in order to preserver memory function. 1. A method of inhibiting inflammation associated memory dysfunction comprising administering to a patient in need of treatment a composition containing one or more of the following ingredients:{'i': 'Nigella sativa', 'a) Green Tea and/or extract thereof; b) Blueberry and/or extract thereof; c) and/or extract thereof; and d) broccoli and/or extract thereof.'}2. The method of claim 1 , wherein said green tea extract is epigallocatechin-3-gallate or an analogue thereof.3. The method of claim 1 , wherein said blueberry extract is pterostilbene or an analogue thereof.4Nigella sativa. The method of claim 1 , wherein said extract is thymoquinone or an analogue thereof.5. The method of claim 1 , wherein said broccoli extract is sulforaphane or an analogue thereof.6. The method of claim 1 , wherein said therapeutic combination is administered at a dosage and frequency sufficient to inhibit neural inflammation.7. The method of claim 6 , wherein said neural inflammation is microglial activation.8. The method of claim 7 , wherein said microglial activation is upregulation of HLA II on microglia.9. The method of claim 7 , wherein said microglial activation is upregulation of IL-10 production from microglia.10. The method of claim 7 , wherein said microglial activation is upregulation of CD40.11. The method of claim 7 , wherein said microglial activation is upregulation of CD80.12. The method of claim 7 , wherein said microglial activation is upregulation of CD86.13. The method of claim 7 , wherein said microglial activation is upregulation of nitric oxide production14. The method of claim 1 , ...

Compositions and methods for nutritional supplements

Compositions and methods are presented in which a plurality of chemically distinct polyphenols inhibit multiple enzymes in pathways associated with health and healthy ageing. Preferred compositions are derived from colored plant materials that are commonly found in the Mediterranean diet and provide the biochemical basis for the health benefits of the Mediterranean diet. Notably, the enzyme inhibition observed with the combined polyphenols was synergistic with respect to not one but a significant number of enzymes in the pathways associated with health and healthy ageing, thus providing an amplified desirable effect.

COMPOSITION AND METHOD TO TREAT AND ALLEVIATE SYMPTOMS OF HOT FLASHES IN A FEMALE SUBJECT

A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of hot flashes in a female subject, such as experiencing symptoms of perimenopause. The composition includes a phytoestrogen and lycopene in an oral dosage form. The phytoestrogen may include a plant lignan including at least one of Matairesinol, 7-hydroxymatairesinol, Secoisolariciresinol, Lariciresinol and Pinoresinol. The lycopene may include a lycopene complex having at least one of phytoene, phytofluene, beta-carotene, tocopherols and phytosterols. 118-. (canceled)19. A method of treating and alleviating symptoms of hot flashes in a female subject by administering to the female subject in need thereof a therapeutic amount of a dietary supplement composition comprising a phytoestrogen and lycopene in an oral dosage form.20. The method according to claim 19 , wherein the female subject is a female experiencing symptoms of perimenopause.21. The method according to claim 19 , wherein the phytoestrogen comprises a plant lignan including at least one of Matairesinol claim 19 , 7-hydroxymatairesinol claim 19 , Secoisolariciresinol claim 19 , Lariciresinol claim 19 , Pinoresinol claim 19 , sesame seed oil claim 19 , and sesamin.22. The method according to claim 21 , further comprising delivering 10 to 50 mg of HMR Lignans as 7-hydroxymatairesinol.23. The method according to claim 22 , further comprising delivering 20 to 45 mg of HMR Lignans as 7-hydroxymatairsesinol.24. The method according to claim 19 , wherein the phytoestrogen comprises an enterolactone precursor.25. The method according to claim 19 , wherein the lyocopene comprises a lycopene complex comprising at least one of phytoene claim 19 , phytofluene claim 19 , beta-carotene claim 19 , tocopherols and phytosterols.26. The method according to claim 19 , further comprising delivering 2 to 10 mg of lycopene.27. The method according to claim 26 , further comprising delivering 4 to 8 mg of lycopene.28. The ...

COMPOSITIONS AND METHODS FOR CONTROLING CARBOHYDRATE AND FAT METABOLISM

The subject of the invention is a composition comprising at least a mixture of molecules obtained at least from: 1. A composition consisting at least of:{'i': Chrysanthellum indicum, Cynara scolymus, Vaccinium myrtillus, Piper', 'Olea europaea, 'an extract obtained from a blend of at least and , and/or'} [{'i': Chrysanthellum indicum, Cynara scolymus, Vaccinium myrtillus', 'Olea europaea, 'an extract obtained from a blend of at least and , and'}, 'pipérine, and/or, 'a mixture of [{'i': Chrysanthellum indicum, Cynara scolymus, Vaccinium myrtillus', 'Olea europaea, 'an extract obtained from a blend of at least and , and'}, {'i': 'Piper', 'an extract of containing piperine.'}], 'a mixture of2PiperPiper nigrum, Piper aduncumPiper longum.. The composition of claim 1 , wherein the plant is chosen from and3Chrysanthellum indicum. The composition of claim 1 , wherein the blend comprises whole plant and/or aerial parts.4Cynara scolymus. The composition of claim 1 , wherein the blend comprises whole plant and/or leaves.5Vaccinium myrtillus. The composition of claim 1 , wherein the blend comprises whole plant and/or fruit.6. The composition of claim 1 , wherein the composition comprises a mixture of the following molecules:at least one molecule chosen from apigenin 7-O-glucuronide, chrysanthellin A, chrysanthellin B, caffeic acid, luteolin, maritimetin, eriodictyol, isookanin, apigenin, luteolin 7-O-glucoside, maritimein, marein, eriodictyol 7-O-glucoside, flavomarein, apigenin 8-C-α-L-arabinoside-6-C-β-D-glucoside (shaftoside), apigenin 6,8-C-di-β-D-glucopyranoside (vicenin-2), or analogs thereof,at least one molecule chosen from a dicaffeoylquinic acid, a sulfo-monocaffeoylquinic acid, luteolin, luteolin 7-O-glucoside, luteolin 7-O-glucuronide, apigenin 7-O-glucoside, cynaropicrin, or analogs thereof,at least one molecule chosen from a monocaffeoylquinic acid, delphinidin 3-galactoside, delphinidin 3-glucoside, cyanidin 3-galactoside, delphinidin 3-arabinoside, cyanidin 3- ...

USE OF CRANBERRY PROANTHOCYANIDIN FOR TREATMENT OF OROPHARYNGEAL BACTERIAL COLONIZATION

The present invention relates to a method for preventing Gram-negative bacterial colonization of an oropharyngeal material, the said method comprising bringing into contact a composition comprising a cranberry-derived proanthocyanidin extract on at least a part of the surface area of the said material. 1Pseudomonas aeruginosa, Acinetobacter baumanniiStaphylococcus aureus.. A method for locally reducing oropharyngeal colonization of bacteria causing nosocomial respiratory infections , in a mammal , comprising administering to the mammal a composition comprising a cranberry-derived proanthocyanidin extract , the bacteria causing nosocomial respiratory infections being selected from the group consisting of Enterobacteriaceae bacteria , , and2Pseudomonas aeruginosa, Acinetobacter baumanniiStaphylococcus aureus.. A method for preventing and/or treating lung infection by bacteria causing nosocomial respiratory infections , in a mammal , comprising administering to the mammal a composition comprising a cranberry-derived proanthocyanidin extract , the bacteria causing nosocomial respiratory infections being selected from the group consisting of Enterobacteriaceae bacteria , and3Pseudomonas aeruginosa, Acinetobacter baumanniiStaphylococcus aureus.. A method for in vivo inhibiting adherence of bacteria causing nosocomial respiratory infections to a surface of oropharyngeal epithelial cells in a mammal , comprising administering to the mammal a composition comprising a cranberry-derived proanthocyanidin extract , the bacteria causing nosocomial respiratory infections being selected from the group consisting of Enterobacteriaceae bacteria , and4. The method according to claim 1 , wherein the cranberry-derived proanthocyanidin extract is present in a concentration of at least 50 μg/mL.5Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumanniiStaphylococcus aureus.. The method according to claim 1 , in which the bacterium ...

HERBAL COMPOSITIONS FOR TREATING PAIN AND SKIN DISORDERS

The invention relates to herbal compositions having standalone preparations of two phytochemicals, Bakuchiol and Boswellic acid as well as synergistic combinations of Bakuchiol with either oil or boswellic acid or both. Bakuchiol in these compositions has assay by HPLC of greater than 50%, whereas boswellic acid is standardized to at least 20% of 3-o-Acetyl-11-keto-beta-boswellic acid. The compositions are either oral—for relief and remission of proliferative skin disorders or topical—for the treatment and management of pain. The invention further provides process of preparation of these compositions. The invention also relates to use of the compositions for treating pain or proliferative skin disorders and various dosage regimens. 171.-. (canceled)72Boswellia. A composition for the treatment/management of pain or skin disorders , comprising: from around 1% to around 15% of Bakuchiol by weight and further comprising oil or Boswellic acid or combinations thereof and optionally any other therapeutic agent.73. The composition according to claim 72 , wherein the composition is in or al or topical form.74. The composition according to claim 73 , wherein the composition is an oral composition.75. The composition according claim 74 , to claim 74 , wherein a ratio of Boswellic acid to Bakuchiol is from 30:1 to 1:5.76. The composition according to claim 75 , wherein the ratio of Boswellic acid to Bakuchiol is preferably from 15:1 to 1:2 and most preferably from 12:1 to 2:1.77. The composition according to claim 74 , wherein Boswellic acid has at least 20% of 3-o-Acetyl-11-keto p-Boswellic acid by weight.78. The composition according to claim 74 , wherein total of Bakuchiol and Boswellic acid is from 30-90% of the total composition by weight.79. The composition according to claim 73 , wherein the composition is a topical composition.80. The composition according to claim 79 , wherein the topical composition is a topical cream claim 79 , comprising one or more ingredients ...

Eye Health Supplement

An eye health supplement administered to a person in order to prevent and treat eye-related conditions or diseases. The eye health supplement focuses on treating conditions and diseases, such as diabetic retinopathy, macular degeneration, hypertensive retinopathy, keratoconjunctivitis sicca, and more, and the underlying symptoms of eye-related conditions and diseases through the inclusion of a quantity of birch leaf powder, a quantity of pomegranate, a quantity of garlic bulb powder, a quantity of fenugreek powder, a quantity of curcumin, a quantity of asthaxanthin, a quantity of bilberry extract powder, and a quantity of glutathione powder. The quantity of birch leaf powder, the quantity of pomegranate, the quantity of garlic bulb powder, the quantity of fenugreek powder, the quantity of curcumin, the quantity of asthaxanthin, the quantity of bilberry extract powder, and the quantity of glutathione powder are heterogeneously mixed into a supplement mixture for oral or transdermal administration. 1. An eye health supplement comprises:a quantity of birch leaf powder;a quantity of pomegranate;a quantity of garlic bulb powder;a quantity of fenugreek powder;a quantity of curcumin;a quantity of asthaxanthin;a quantity of bilberry extract powder;a quantity of glutathione powder; andthe quantity of birch leaf powder, the quantity of pomegranate, the quantity of garlic bulb powder, the quantity of fenugreek powder, the quantity of curcumin, the quantity of asthaxanthin, the quantity of bilberry extract powder, and the quantity of glutathione powder being heterogeneously mixed into a supplement mixture.2. The eye health supplement as claimed in comprises:the quantity of birch leaf powder being approximately 3.2% by weight (wt) of the supplement mixture.3. The eye health supplement as claimed in comprises:the quantity of pomegranate being approximately 6.5% wt of the supplement mixture.4. The eye health supplement as claimed in comprises:the quantity of garlic bulb powder ...

Unknown

A dietary supplement including monacolin K, phytosterols, policosanols, resveratrol, trimethylglycine and coenzyme Q10 is provided. 1. A dietary supplement comprising monacolin K , phytosterols , policosanols , resveratrol , trimethylglycine and coenzyme Q10.2Oryza sativaCyclanthera pedataSaccharum officinarumGlycine maxBeta vulgarisPolygonum cuspidatum. The dietary supplement according to claim 1 , comprising extract containing monacolin K claim 1 , extract containing phytosterols claim 1 , extract containing policosanols claim 1 , extract containing coenzyme Q10 claim 1 , extract containing trimethylglycine claim 1 , and extract containing resveratrol.3Oryza sativaCyclanthera pedataSaccharum officinarumGlycine maxBeta vulgarisPolygonum cuspidatum. The dietary supplement according to claim 2 , wherein the content of said extract is substantially in the range of 10% to 5%; wherein the content of said extract is substantially in the range of 2% to 6%; wherein the content of said extract is substantially in the range of 1% to 5%; wherein the content of said extract is substantially in the range of 1% to 5%; wherein the content of said extract is substantially in the range of 22% to 23%; and wherein the content of said extract is substantially in the range of 13% to 14%.4Medicago sativaMedicago sativa. The dietary supplement according to claim 1 , comprising extract and wherein the content of said extract is selected from between 55% and 65% and between 15% and 20%.5Cynara scolymusCynara scolymus. The dietary supplement according to claim 1 , comprising extract and wherein the content of said extract is substantially in the range of 10% to 5%.6Porphyra umbilicalisPorphyra umbilicalis. The dietary supplement according to claim 1 , comprising extract and wherein the content of said extract is substantially in the range of 3% to 7%.7Chondrus crispusChondrus crispus. The dietary supplement according to claim 1 , comprising extract and wherein the content of said extract is ...

Growth supplement for efficient production of agricultural and livestock products

Provided is a growth supplement for efficient production of agricultural and livestock products, more specifically, a growth supplement for environment-friendly crop cultivation and livestock rearing to increase yields of crops and livestock, which is prepared by mixing specific amounts of antibiotic fruit juices, one or more sources of sugar, one or more sources of hydrogen carbonate, one or more sources of chloride ion and antifebrile vegetable juices depending on crops (species) and cultivation (livestock) conditions to feed the livestock or crops. The growth supplement is prepared by admixing and stirring antibiotic fruit juices in an amount of 2 to 10 parts by weight; the source of hydrogen carbonates in an amount of 1 to 4 parts by weight; the source of chloride ion in an amount of 1 to 4 parts by weight; and antifebrile vegetable juices in an amount of 2 to 8 parts by weight, based on 100 parts by the source of sugar.

COMPOSITIONS FOR THE TREATMENT OF PERIPHERAL ULCERS OF VARIOUS ORIGINS

The present invention relates to combinations of an agent that stimulates cell proliferation and an anti-inflammatory/analgesic, which are useful in the treatment of peripheral ulcers of various origins, such as radiation dermatitis, diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores, and the associated skin infections, proctitis, vulvovaginitis and haemorrhoids with vascular lesions. These combinations can be presented as formulations for topical use. 1. A composition comprising:{'i': 'Vaccinium myrtillus,', 'a) bisulphite adducts of anthocyanosides from'}{'i': 'Echinacea', 'b) a lipophilic extract of sp..'}2EchinaceaEchinacea angustifoliaEchinacea purpurea.. The composition according to claim 1 , wherein the lipophilic extract of sp. is a lipophilic extract of or3Echinacea. The composition according to containing 0.05 to 2% of said bisulphite adducts and 0.01 to 1% of said lipophilic extract of sp.4. The composition according to suitable for topical administration.5. A composition comprising{'i': 'Vaccinium myrtillus,', 'a) bisulphite adducts of anthocyanosides from'}{'i': 'Vaccinium myrtillus', 'b) anthocyanosides from ; and'}{'i': 'Echinacea', 'c) a lipophilic extract of sp.'}6EchinaceaEchinacea angustifoliaEchinacea purpurea.. The composition according to claim 5 , wherein the extract of sp. is a lipophilic extract of or7Echinacea. The composition according to containing 0.05 to 2% of said bisulphite adducts and 0.01 to 1% of said lipophilic extract of sp.8. The composition according to suitable for topical administration. This U.S. non-provisional application is a divisional of U.S. application Ser. No. 14/935,036 filed on Nov. 6, 2015, which is a continuation of U.S. application Ser. No. 14/342,618 filed on Mar. 20, 2014, now U.S. Pat. No. 9,278,084, which is a U.S. National Stage of PCT/EP2012/067893 filed on Sep. 13, 2012, which claims priority to and the benefit of Italian Application No. MI2011A001671 filed on Sep. 16, 2011, the ...

TECAP Liquid

The present disclosure relates to a natural product drink formula and method, which safely aids in the balancing of vaginal pH, reducing vaginal odor, and/or reducing body odor of the user. The present disclosure may comprise natural ingredients including vitamins and minerals. The present disclosure may be in the form of a powder, a gel, a solid, or a liquid which is later added to water or can be make directly as a liquid drink. 1. A composition for balancing vaginal pH consisting essentially of therapeutic amounts of watermelon juice , ground chicken feet , lemon leaves , snakeroot , Amaranth seed , ground oxtail bone , cranberry vine leaf , and distilled water.2. The composition of claim 1 , wherein the composition corresponds to a pill.3. The composition of claim 1 , wherein the composition corresponds to a gel.4. The composition of claim 1 , wherein the composition corresponds to a powder.5. The composition of claim 1 , wherein the composition corresponds to a liquid.6. An aqueous beverage for balancing vaginal pH wherein a gallon serving comprises:¼ tsp ground chicken foot powder;⅛ tsp ground oxtail bone powder;⅓ cup conch peas;¼ tsp. amaranth seed oil;1/10 tsp. snake root leaf powder;5 cups cranberry;10 oranges;2 lemons;1 cup pomegranate juice;½ tsp brassica powder;½ carrot powder;2 Bunches collard greens;⅛ Hibiscus leaf oil;2 cups of Watermelon;Malic acid;potassium sorbate;citric acid; glycerin;and sorbitol. The present application claims priority to U.S. provisional patent application No. 62/370,859 filed Aug. 4, 2016 the entire contents of which are incorporated herein by reference.The present invention relates generally to a drink formula. More specifically, the present invention is a liquid combination of natural products, juices and vitamins that alleviates or helps prevent vaginal odor, body odor and/or balances the internal pH of the user.The present disclosure relates to a natural product drink and method of use thereof.Foul odors can be caused by ...

Creatine Nutritional Supplement

Disclosed herein is a nutritional supplement containing apple cider vinegar (ACV). including compositions, formulations, and combinations of ingredients in the ACV nutritional supplement, as well as processes for manufacturing these supplements. The disclosed nutritional supplement can include ACV, a gelling agent such as pectin or gelatin, an oligosaccharide, a disaccharide, and water.

Cranberry Extract Useful in the Treatment and Prevention of Urinary Infections

The present invention relates to a concentrated extract of cranberry (), the complex composition of which makes it possible to increase the antibacterial effects thereof, which is of use for the prevention or treatment of urinary infections, and in particular for the preventive treatment of urinary infections or treatment against the recurrence thereof. The invention also relates to a process for preparing such an extract, to food, nutraceutical or pharmaceutical compositions comprising the extract and to the use thereof in the treatment or prevention of urinary infections. 2. The dry cranberry extract according to claim 1 , wherein the dry cranberry extract is a de-esterified extract.3. The dry cranberry extract according to claim 1 , wherein the polymers of PACs having a degree of polymerization greater than or equal to 4 represent at least 30% by weight claim 1 , in relation to the weight of all PACs present in the extract.5. The process according to claim 4 , wherein:the water-soluble fraction used in step a) is cranberry juice and the water-insoluble fraction used in step b) is cranberry marc, or i) Crushing whole cranberries, and', 'ii) Decanting and separating the water-soluble and water-insoluble fractions., 'The water-soluble fraction used in step a) and the water-insoluble fraction used in step b) were obtained from whole cranberries, by6. The process according to claim 4 , wherein fraction I is obtained in step a) by the following steps: adsorption of the water-soluble fraction on a non-polar support,', 'washing with a polar solvent and collecting polar fraction Ia, and', 'eluting and collecting non-polar fraction Ib;, 'a1) separating non-polar compounds and polar compounds by adsorption of fraction Ia on ion-exchange resin,', 'washing with aqueous solvent,', 'eluting with acidic solvent and collecting fraction Ic comprising organic acids;, 'a2) separating organic acids and sugars present in polar fraction Ia bya3) Combining fractions Ib and Ic to form ...

COMPOSITIONS CONTAINING PLANT EXTRACTS AND APPLICATIONS THEREOF

Provided is a composition for reducing the fat content of fat-producing cells and applications thereof. The composition includes plant extracts such as a blueberry extract and a black tea extract. 1ginsengginseng. A composition comprising a plant extract , wherein the composition comprises a combination selected from the group consisting of a blueberry extract and a black tea extract , a blueberry extract and a green tea extract , a red wine extract and a black tea extract , a red wine extract and a green tea extract , a red wine extract and a Pu-erh tea extract , a red wine extract and a Four Seasons Spring tea extract , a red wine extract and a citrus extract , a red wine extract and a spinach extract , a red wine extract and a green coffee bean extract , a citrus extract and a broccoli sprout extract , a citrus extract and a red clover extract , a citrus extract and an aloe extract , a citrus extract and a rosemary extract , a citrus extract and a garlic extract , a citrus extract and a pepper extract , a citrus extract and a turmeric extract , a citrus extract and a wolfberry extract , a citrus extract and a extract , a citrus extract and apple polyphenols , a citrus extract and β-carotene , a citrus extract and lycopene , a spinach extract and a red clover extract , a spinach extract and a rosemary extract , a spinach extract and a garlic extract , a spinach extract and a turmeric extract , a spinach extract and a wolfberry extract , a spinach extract and a extract , a spinach extract and apple polyphenols , and a spinach extract and β-carotene.2. The composition of claim 1 , wherein the composition comprises one of the following combinations: at least 0.0625 mg/ml of the blueberry extract and at least 0.0625 mg/ml of any one of the black tea extract and the green tea extract.3. The composition of claim 1 , wherein the composition comprises one of the following combinations: at least 0.0625 mg/ml of the red wine extract and at least 0.0625 mg/ml of any one of ...

HEALTH DRINK COMPOSITION FOR PREVENTING LIVER DAMAGE CAUSED BY ALCOHOL WHILE PROVIDING EXCELLENT HANGOVER RELIEF

A drink composition for preventing alcohol-induced liver damage, which is effective for hangover relief and which contains 2 to 4 wt % of black ginseng, 4 to 7 wt % of blueberry, 0.3 to 1 wt % of dry yeast, 0.5 to 1.5 wt % of jujube pulp, and 2 to 4 wt % of oriental raisin tree fruit and is produced by hot-water extraction using the remaining wt % of purified water. The composition has a liver damage suppressing effect, reduces hepatitis activity index, and thus may be used as a composition capable of preventing or treating various liver diseases. Furthermore, it has very excellent effects on alcohol degradation and acetaldehyde degradation, alleviates headache and vomiting symptoms the next day after drinking, and thus is also very useful as a composition for liver protection or hangover relief, which is taken before and after alcohol drinking. 1. A drink composition for preventing alcoholic liver disease or relieving hangover , which contains 2 to 4 wt % of black ginseng , 4 to 7 wt % of blueberry , 0.3 to 1 wt % of dry yeast , 0.5 to 1.5 wt % of jujube pulp , and 2 to 4 wt % of oriental raisin tree fruit and is produced by hot-water extraction using a remaining wt % of purified water.2. The drink composition of claim 1 , which further contains 2 to 4 wt % of green onion root and is produced by hot-water extraction.3. The drink composition of claim 1 , which further contains 2 to 4 wt % of radish greens and is produced by hot-water extraction.4. The drink composition of claim 1 , wherein the alcoholic liver disease is alcoholic hepatitis claim 1 , alcoholic fatty liver claim 1 , or alcoholic liver cirrhosis.5. The drink composition of claim 2 , which further contains 2 to 4 wt % of radish greens and is produced by hot-water extraction.6. The drink composition of claim 2 , wherein the alcoholic liver disease is alcoholic hepatitis claim 2 , alcoholic fatty liver claim 2 , or alcoholic liver cirrhosis. The present invention relates to a composition for preventing or ...

WEIGHT LOSS FORMULATION

A weight loss product comprises a mixture of , and (in the weight proportion 12:10:5:4), to which additional ingredients have been added to increase weight loss efficacy. The additional ingredients may include, but are not limited to, Gamma-oryzanol, Caffeine, Cirsimarin, Fucoxanthin, Guggulsterones, Evodiamine, Forskolin, Sclareolide, Chromium, Hydroxycitric acid, Pinolenic acid, Conjugated linoleic acid, Potato protein, Raspberry ketone, Capsaicin, Synephrine, Dehydroepiandrosterone, Phenylethylamine, Orlistat, Glucomannan, or Vitamin C, or sources thereof, as well as herbal ingredients such as , Damiana, Green tea, Green coffee bean, Cinnamon, White kidney bean, , Nopal Cactus, Hoodia, Yohimbine, , Cayenne, Pomegranate, Blueberry, Billberry, or extracts of such herbal ingredients, and plant sources of antioxidants. A preferred additional ingredient is caffeine provided by caffeine anhydrous, , and kola nut. Other additional ingredients may be used as well in accordance with specific disclosed formulations. 1. A weight loss composition comprising:{'i': Alchemilla vulgaris, Olea europaea, Cuminum cyminum', 'Mentha longiflora, 'a mixture of , and ; and'} (i) Gamma-oryzanol, Caffeine, Cirsimarin, Fucoxanthin, Guggulsterones, Evodiamine, Forskolin, Sclareolide, Chromium, Hydroxycitric acid, Pinolenic acid, Conjugated linoleic acid, Potato protein, Raspberry ketone, Capsaicin, Synephrine, Dehydroepiandrosterone, Phenylethylamine, Orlistat, Glucomannan, or Vitamin C, or sources thereof, or', {'i': Guarana, Yerba Mate', 'Garcinia Cambogia', 'Malpighia glabra, Eurycoma Longifolia, Caralluma Fimbriata, Citrus aurantium, Gymnema Sylvestre, Lyceum barbarurn, Aloe Vera', 'Punica granatum, '(ii) herbal ingredients selected from the group comprising , Damiana, Green tea, Green coffee bean, Cinnamon, White kidney bean, , Nopal Cactus, Hoodia, Yohimbine, , Cayenne, , Blueberry, Billberry, or extracts thereof.'}], 'at least one additional ingredient selected from one of the ...

Analgesic Formulation and Delivery Bandage

A medical dressing and analgesic formulation that is operable to provide pain relief to an injured area of the human body wherein the medical dressing is constructed so as to allow a user to create a customized size for each application of the medical dressing. The medical dressing further includes a body being planar in manner having a plurality of contiguous portions that are separated by a perforation. Each contiguous portion includes a medicament layer thereon that is operable to treat an injured are for pain. The contiguous portions in one embodiment of the medical dressing are further configured to be divisible into four quadrants wherein the user can select as few as one quadrant or more than one quadrant of each continuous portion so as to size the medical dressing to the appropriate size needed to treat the desired area of the body. 1. An analgesic formulation comprising:Menthol, wherein the menthol is from about 1.25% wt to about 16% wt;Polyacrylic acid, wherein the polyacrylic acid is from about 0.1% wt to about 10% wt; andGlycerin, wherein the glycerin is from about 5% wt to about 80% wt.2. The analgesic formulation as recited in claim 1 , and further comprising from 5% wt to about 75% of Pine Resin and 0.01% wt and to about 1% wt of eucalyptus claim 1 , juniper berry and wintergreen.3. The analgesic formulation as recited in claim 2 , and further comprising from about 0.5% wt to about 5% wt titanium.4. The analgesic formulation as recited in claim 3 , and further comprising from about 0.5% wt to about 5% wt kaolin.5. The analgesic formulation as recited in claim 4 , and further comprising from about 0.01% wt to about 1.2% wt aluminum hydroxide.6. The analgesic formulation as recited in claim 5 , and further comprising from about 60% wt to about 72% wt water.7. The analgesic formulation as recited in claim 6 , wherein the analgesic formulation is prepared in a form selected from one of the following forms consisting of: a gel claim 6 , a lotion claim 6 , ...

Upregulation of Therapeutic T Regulatory Cells and Suppression of Suicidal Ideations in Response to Inflammation by Administration of Nutraceutical Compositions Alone or Combined with Minocycline

Disclosed are compositions of matter, treatments and protocols useful for induction of T regulatory cells in response to inflammation, as well as inhibition of suicidal ideations and/or neuroinflammation. In some embodiments the invention teaches the administration of a therapeutic combination of ingredients comprising of minocycline, pterostilbene, , sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal undergoing upregulation of inflammatory mediators. In another embodiment, the invention teaches administration of said therapeutic combination to a mammal infected with said SARS-CoV-2 and/or possessing suicidal ideations. In some embodiments dosage of said therapeutic combination is based on inflammatory and/or immunological parameters observed in patients.

SYSTEMS AND METHODS FOR THROMBOSIS PREVENTION

The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E. 1. A method of treating or reducing a complication of a viral or bacterial infection , the method comprising administering to the subject a composition comprising eicosapentaenoic acid (EPA) and an antioxidant.2. The method of claim 1 , wherein the complication comprises a cardiovascular condition.3. The method of claim 1 , wherein the complication comprises a blood clot or thrombosis that forms in the vascular system.4. The method of claim 1 , wherein the complication comprises a deep vein thrombosis.5. The method of claim 1 , wherein the complication comprises fibrin formation in the vascular system.6. The method of claim 1 , wherein the complication comprises cognitive brain function.7. The method of claim 1 , wherein the composition comprises fish oil comprising the EPA.8. The method of claim 1 , wherein the antioxidant comprises Vitamin E.9. The method of claim 1 , further comprising administering an antiplatelet agent.10. The method of claim 1 , further comprising administering a coumarin component comprising coumarin or a coumarin derivative.11. A method of treating or preventing thrombosis:(a) in a subject suffering from a viral and/or bacterial infection or from one or more complications thereafter or (b) in small vessels in a subject in need thereof,the method comprising administering to the subject a composition comprising eicosapentaenoic acid (EPA) and an antioxidant.12. The method of claim 11 , wherein the thrombosis is formed in an artery claim 11 , arteriole claim 11 , capillary claim 11 , venule claim 11 , and/or vein.13. The method of claim 11 , wherein the composition comprises fish oil comprising the EPA.14. The method of claim 11 , wherein the antioxidant comprises Vitamin E.15. The method of claim 11 , further comprising administering an ...

METHODS, COMPOSITIONS, AND KITS ADDRESSING DEPRESSED MOOD

A method of treating or preventing postpartum blues or depression is described, comprising administering to a subject in need thereof: an antioxidant source; a tryptophan composition comprising from 1.0 g to 5.0 g of tryptophan; and a tyrosine composition comprising from 2.0 g to 50 g of tyrosine. The antioxidant source may comprise a food or an extract derived from such a food as grapes, berries such as blueberries, citrus fruit, pomegranate, tomato, squash, carrot, sweet potato, dark green vegetables, beets, leafy vegetables, vegetables, peppers, melons, pineapples, lentils, plant oils, and/or tree nuts. 1. A method of treating or preventing postpartum blues or depression comprising administering to a subject in need thereof:an antioxidant source;a tryptophan composition comprising from 1.0 g to 5.0 g of tryptophan; anda tyrosine composition comprising from 2.0 g to 50 g of tyrosine.2. The method of claim 1 , wherein the antioxidant source comprises a food.3. The method of claim 1 , wherein the antioxidant source comprises a composition comprising a plant extract and an acceptable diluent.4. The method of claim 1 , wherein the antioxidant source comprises:{'i': 'Brassica oleracea', 'grapes, berries, citrus fruit, pomegranate, tomato, squash, carrot, sweet potato, a dark green vegetable, a beet, a leafy vegetable, a vegetable, a pepper, a melon, pineapple, lentils, a plant oil, and/or a tree nut; and/or a juice, extract, or isolated antioxidant compound therefrom.'}5. The method of claim 1 , wherein the antioxidant source comprises blueberries claim 1 , blueberry juice claim 1 , blueberry extract claim 1 , and/or an anthocyanin isolated from blueberry.6. The method of claim 1 , wherein the antioxidant source comprises an anthocyanin.7. The method of claim 1 , wherein the antioxidant source has an ORAC value at least about 3000 μmol TE/serving.8. The method of claim 1 , wherein the antioxidant source has an ORAC value of at least about 5000 μmol TE/serving.9. The ...

ANTI-MICROBIAL AMALGAMATE OF NON-TOXIC NATIVE COMPOSITION

An anti-microbial formulation of native ingredients for human and non-human vertebrate animal feeds, feed supplements/additives, or for direct doses to replace in whole or supplement traditional anti-microbial with side-effects such as allergies, microbial-resistance, and drug-interactions with non-toxic, side-effect free native anti-microbial for all vertebrates. The invention comprises of non-toxic, side-effect free native substances amalgamations having anti-microbial properties for food additives, food supplements, or direct doses. Furthermore, these native formulas can be use with or without other prescription or nonprescription anti-microbial medications. We describe the method of manufacture and also the process of use for this amalgamates. 1. An anti-microbial composition comprising coconut/MCT oil , Elantria DHA 400 algae , cranberry seed , black cumin , oregano , carob , and Agaricus mushroom; wherein the composition is side-effect-free in any vertebrate; and wherein the composition is non-toxic to any vertebrates.2. The composition of claim 1 , further comprises at least one or more selected from chia claim 1 , krill claim 1 , micro-algae claim 1 , cinnamon claim 1 , lemon claim 1 , coriander claim 1 , ginger claim 1 , peppermint claim 1 , fenugreek claim 1 , moringa claim 1 , insect protein claim 1 , cardamom claim 1 , or any combination thereof.3. The composition of any of claim 1 , wherein krill comprises from 5% to 40% by weight/volume claim 1 , wherein micro-algae comprises from 5% to 40% weight/volume claim 1 , wherein cranberry seed comprises from 0.1% to 10% by weight/volume claim 1 , wherein chia comprises from 5% to 30% by weight/volume claim 1 , wherein black cumin comprises from 0.05% to 5% by weight/volume claim 1 , wherein carob comprises from 0.1% to 5% by weight/volume claim 1 , and wherein cardamom comprises from 0.01% to 5% by weight/volume or any combination thereof.4. The composition of claim 1 , wherein oregano oil 11-24% claim 1 , ...

Methods, compositions, and kits addressing depressed mood

Kits for the treatment or prophylaxis of depressed mood are described, for subjects with increased MAO-A levels, excessive crying, or subjects within or beyond the 5-day postpartum period. The kits are used to implement a method by which the subject is administered an antioxidant source on at least the first day of a 3 to 5 day regime; a tryptophan composition on the evening of the penultimate treatment day, simultaneously or following the antioxidant source; and a tyrosine composition the day after the tryptophan composition, on the final treatment day. The kit comprises an antioxidant source which may comprise or be derived from blueberries. Individuals with depressed mood due to perimenopause, alcohol use disorders or withdrawal, or who are up to or beyond 18-months postpartum, may benefit from the kits. The kits described may reduce the likelihood of advancing from depressed mood to depression.

METHOD OF ENHANCING THE GENE EXPRESSION LEVEL OF TGM1, KRT, AQP3, FLG, GBA, AND HAS USING PLANT EXTRACTS

The present invention provides a method of a composition containing plant extracts for enhancing the gene expression level of TGM1, KRT, AQP3, FLG, GBA, and HAS. Compared to a single plant extract, the combination of the plant extracts of the present invention can more effectively enhance the expression level of skin moisturizing genes. The plant extracts constituting the composition include: an extract of spinach, blueberry, Pu-erh tea, or Four Seasons Spring tea. 1. A method of enhancing expression of transglutaminase 1 (TGM1) , keratin (KRT) , aquaporin 3 (AQP3) , filaggrin (FLG) , glucocerebrosidase (GBA) , and hyaluronic synthase (HAS) genes , comprising administering to a subject in need thereof a composition comprising an effective amount of a plant extract; wherein the plant extract comprises at least one combination selected from the group consisting of a Pu-erh tea extract and a blueberry extract , a Pu-erh tea extract and a spinach extract , a Four Seasons Spring tea extract and a blueberry extract , and a Four Seasons Spring tea extract and a spinach extract.2. The method according to claim 1 , wherein the KRT gene comprises keratin 1 (KRT1) claim 1 , keratin 10 (KRT10) claim 1 , and keratin 14 (KRT14).3. The method according to claim 1 , wherein the HAS gene comprises hyaluronic synthase 2 (HAS2) and hyaluronic synthase 3 (HAS3).4. The method according to claim 1 , wherein the plant extract comprises at least 0.125 mg/mL of the Pu-erh tea extract and at least 0.125 mg/mL of the spinach extract.5. The method according to claim 1 , wherein the plant extract comprises at least 0.125 mg/mL of the Four Seasons Spring tea extract and at least 0.125 mg/mL of the spinach extract.6. The method according to claim 1 , wherein the plant extract comprises at least 0.25 mg/mL of the Pu-erh tea extract and at least 0.25 mg/mL of the blueberry extract.7. The method according to claim 1 , wherein the plant extract comprises at least 0.25 mg/mL of the Pu-erh tea extract ...

Cosmetic compositions

A method of reducing melanogenesis in skin is disclosed. The method can include topically applying to skin in need thereof a composition comprising an effective amount of an aqueous and glycerin extract of Rhododendron ferrugineum (alpine rose) leaf to reduce melanocyte pigmentation in the skin.

ANTI-AGE COMPOSITION COMPRISING A COMBINATION OF ANTIOXIDANT AGENTS IN ASSOCIATION WITH BIFIDOBACTERIA AND CELL WALLS ISOLATED FROM PROBIOTICS

An anti-age composition is described. The anti-age composition comprises a combination of antioxidant agents, such as flavonoids, anthocyanins, tannins, curcumin and derivatives thereof, as well as vitamins A, C and E, in association with Bifidobacteria and cell walls isolated from probiotics which takes into account all the different factors involved in the aging process in order to prevent or slow down the course thereof. 1. A composition , formulated for oral or topical administration , the composition comprising:one or more natural extracts selected from the group consisting of grape seed extract; grape marc extract; bilberry extract; Goji berry extract; curcuma extract; in an amount from 2.5 to 10% by weight relative to the total weight of the composition;one or more substances with anti-oxidant activity selected from the group consisting of vitamin A, vitamin C, vitamin E and acetylcysteine in an amount from 0.1 to 1.0% by weight relative to the total weight of the composition;zinc and selenium in an amount from 0.005 to 0.02% by weight relative to the total weight;probiotics selected from live bacteria of Bifidobacterium bifidum, in an amount of 10×8-10×10 cfu/g; and/orcell walls isolated from a bacteria selected from the group consisting of Bifidobacterium bifidum, Bifidobacterium infantis/longum, Lactobacillus aerophilus and Lactobacillus plantarum in an amount from 0.0025 to 0.025% by weight relative to the total weight of the composition.2. The composition according to claim 1 , wherein claim 1 , for a topical application claim 1 , the composition is devoid of live bacteria of Bifidobacterium bifidum.3. An oral pharmaceutical formulation comprising the composition according to and common excipients.4. A topical pharmaceutical formulation comprising the composition according to and common excipients.5. A nutraceutical formulation comprising the composition according to claim 1 , with or without common excipients.6. A cosmetic formulation comprising the ...

System for Preparing Medicinal Beverages Using Cartridge-Type Beverage Brewers

A system for brewing medicinal beverages, using a cartridge-based beverage formation apparatus, comprises a cartridge containing a beverage composition comprising a mixture of one or more water-soluble active pharmacological treatment agents, such as pain relievers, cold medications, sleeping aids, laxatives, stimulants, or vitamins, and one or more water-soluble non-pharmacological constituents, which can include water-soluble carbohydrates, proteins, alcohols, sweetening, flavoring and coloring agents, anti-caking agents, buffering and acidifying agents, surfactants, thickening and stabilizing agents, antioxidants and/or preservatives. 1. A system for brewing medicinal beverages using a cartridge-based beverage formation apparatus , the system comprising:a cartridge, adapted for use with the cartridge-based beverage formation apparatus; andcontained within the cartridge, a beverage composition comprising a mixture of one or more water-soluble active pharmacological treatment agents and one or more water-soluble non-pharmacological constituents.2. The system of claim 1 , wherein the beverage composition comprises 0.001 to 6.0 grams of the one or more water-soluble active pharmacological treatment agents claim 1 , mixed with 0.1 to 20 grams of the one or more water-soluble non-pharmacological constituents claim 1 , in powdered or agglomerated form claim 1 , and wherein the one or more water-soluble non-pharmacological constituents are selected from the group consisting of carbohydrates claim 1 , alcohols and proteins.3. The system of claim 2 , wherein the one or more water-soluble non-pharmacological constituents are selected from the group of carbohydrates claim 2 , alcohols and proteins claim 2 , consisting of dextrose claim 2 , fructose claim 2 , sucrose claim 2 , sorbitol claim 2 , mannitol claim 2 , allulose claim 2 , polydextrose claim 2 , soluble dextrins claim 2 , maltodextrins claim 2 , corn syrup solids claim 2 , spray dried or agglomerated natural honey ...

COMPOSITIONS FOR THE TREATMENT OF PERIPHERAL ULCERS OF VARIOUS ORIGINS

The present invention relates to combinations of an agent that stimulates cell proliferation and an anti-inflammatory/analgesic, which are useful in the treatment of peripheral ulcers of various origins, such as radiation dermatitis, diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores, and the associated skin infections, proctitis, vulvovaginitis and haemorrhoids with vascular lesions. These combinations can be presented as formulations for topical use. 1. A composition comprising:{'i': 'Vaccinium myrtillus,', 'a) bisulphite adducts of anthocyanosides from'}{'i': 'Echinacea', 'b) a lipophilic extract of sp.'}2EchinaceaEchinacea angustifoliaEchinacea purpurea.. The composition according to claim 1 , wherein the lipophilic extract of sp. is a lipophilic extract of or3. The composition according to containing 0.05 to 2% of said bisulphite adducts and 0.01 to 1% of said lipophilic extract of Echinacea sp.4. The composition according to suitable for topical administration.5. A method of treating peripheral ulcers claim 1 , radiodermitis induced by radiotherapy and chemotherapy claim 1 , ulcerated haemorrhoids claim 1 , proctitis and vulvovaginitis in a subject in need thereof claim 1 , said method comprising:administering an effective amount of a composition comprising:{'i': 'Vaccinium myrtillus,', 'a) bisulphite adducts of anthocyanosides from'}{'i': 'Echinacea', 'b) a lipophilic extract of sp., to a subject in need thereof; and'}treating said subject.6. The method according to claim 5 , wherein the ulcers are diabetic ulcers claim 5 , ulcers of the limbs due to venous stasis claim 5 , ulcers due to radiation or mechanical or thermal injuries and bedsores.7. A composition comprising{'i': 'Vaccinium myrtillus,', 'a) bisulphite adducts of anthocyanosides from'}{'i': 'Vaccinium myrtillus', 'b) anthocyanosides from ; and'}{'i': 'Echinacea', 'c) a lipophilic extract of sp.'}8EchinaceaEchinacea angustifoliaEchinacea purpurea.. The composition according to ...

NATURAL COMBINATION PRODUCTS AND METHODS FOR REGULATION OF KIDNEY AND EXCRETORY SYSTEM FUNCTION

This invention relates to compositions and methods relating to a combination of naturally-occurring active ingredients useful for the regulation of kidney and excretory system function. The combination of active ingredients, comprising vitamin B, vitamin E, iron, roundhead , birch leaf, and red bilberry, improves the function of kidney structures. The present invention may be used to achieve lower blood nitrogen content, including help to eliminate creatinine, urea, uric acid, by improving glomerular filtration and thus delaying hemodialysis. The present invention may be used to achieve a pronounced anti-inflammatory effect on the kidneys and the urinary tract. The present invention may also be used on its own or as a part of conventional treatment for a long time or indefinitely. 1lespedeza. A composition for the regulation of kidney and excretory system function , comprising vitamin B , vitamin E , iron , roundhead , birch leaf , and red bilberry.2. The composition of claim 1 , wherein the composition includes the following ratio by weight (w/w) of active components:{'sub': '6', 'vitamin Bfrom 0.005% to 3%;'}vitamin E from 0.005% to 8%;iron from 0.005% to 6%;{'i': 'lespedeza', 'roundhead extract from 30% to 60%;'}birch leaf extract from 30% to 60%; andred bilberry extract from 5% to 30%.3. The composition of claim 1 , wherein the composition further comprises excipients in an amount that accounts for about 20% to 40% of the total weight (w/w) of the composition.4. The composition of claim 1 , wherein the composition includes the following amounts by weight (w/w) of active components:{'sub': '6', 'about 4 mg vitamin B;'}about 9 mg vitamin E;about 6 mg iron;{'i': 'lespedeza', 'about 280 mg roundhead extract;'}about 250 mg birch leaf extract; andabout 100 mg red bilberry extract.5. The composition of claim 1 , wherein the composition includes the following amounts by weight (w/w) of active components:{'sub': '6', 'about 4 mg vitamin B;'}about 9 mg vitamin E;about 6 ...

Composition comprising plant extract and use thereof

Provided is a composition comprising a plant extract. The plant extract includes a citrus extract and a green tea extract. The extract combination can effectively increase expression of GLUT4 gene.

Compositions and methods for controlling carbohydrate and fat metabolism

A composition comprising at least: a single extract obtained from a mixture of at least two plants selected from Chrysanthellum indicum, Cynara scolymus, Vaccinium myrtillus, Piper and Olea europaea. This composition is particularly useful as a nutritional product or health product for preventing and/or combating carbohydrate and/or fat metabolism disorders in humans and animals.

Food Supplement For Improving Sports Performance

The present invention relates to the use of a composition for improving sport performances, recuperation and physiological adaptation after doing a normal physical activity, sport, exercises and/or a combination thereof, characterized in that the composition comprises sulphoraphane and/or a precursor of sulphoraphane, and curcumin as active ingredients. 1. A method for improving sport performances , recuperation and physiological adaptation after doing a normal physical activity , sport , exercises and/or a combination thereof in a subject , comprising administering a combination of sulphoraphane and/or a derivative or precursor of sulphoraphane and curcumin to the subject.2. The method of claim 1 , characterized in that sulphoraphane is administered to a subject claim 1 , with a total daily dose of sulphoraphane situated between 200 μg and 60 mg.3. The method of claim 1 , characterized in that the precursor of sulphoraphane is glucoraphanin claim 1 , with a total daily dose of glucoraphanin situated between 200 μg and 60 mg.4. The method of claim 1 , characterized in that the precursor of sulphoraphane is glucoraphanin and wherein a combination of sulphoraphane and glucoraphanin is administered.5. The method of claim 1 , characterized in that a daily dose of curcumin is situated between 30 mg and 300 mg.6. The method of claim 1 , characterized in that sulphoraphane and/or the derivative or precursor of sulphoraphane and curcumin is administered to the subject in one single composition.7. The method of claim 1 , characterized in that a ratio of sulphoraphane and/or the derivative or precursor of sulphoraphane and curcumin is situated between 1:1 and 1:50.8. The method of claim 4 , characterized in that the composition further comprises sulphoraphane and a ratio of sulphoraphane and glucoraphanin is situated between 1:5 and 5:1.9. The method of claim 4 , characterized in that the composition comprises sulphoraphane and a total maximum daily dose of sulphoraphane and ...

SEQUENTIAL EXTRACTION PROCESS

The specification provides methods for extracting proanthocyanidins, especially from firm fruit such as cranberries, through a sequential extraction procedure, and producing infused fruit products. 122-. (canceled)23. A method for processing proanthocyanidin-containing fruit , the method comprising:treating the proanthocyanidin-containing fruit in a first extraction in a tank by bathing the fruit in a first extraction liquid, wherein the first extraction is performed at a temperature of about 75° F. or less;collecting the first extraction liquid to thereby provide a juice extract and once-extracted fruit;treating the once-extracted fruit in a second extraction in a tank by bathing the fruit in a second extraction liquid, wherein the second extraction is performed at a temperature of at least about 90° F. for at least 30 minutes; andcollecting the second extraction liquid to thereby provide a proanthocyanidin-containing extract and twice-extracted fruit.24. The method of claim 23 , wherein the second extraction is performed for about 90 minutes to about 150 minutes.25. The method of claim 23 , wherein the first extraction is performed at a temperature of less than 70° F.26. The method of claim 23 , wherein the second extraction is performed at a temperature of at least about 115° F.27. The method of claim 23 , wherein the second extraction is performed at a temperature of about 110° F. to about 210° F.28. The method of claim 23 , wherein the second extraction extracts at least 10% of the soluble solids that were present in the once-extracted fruit.29. The method of claim 23 , further comprising treating the once-extracted fruit with pectinase enzymes.30. The method of claim 23 , wherein the first extraction liquid is free of added pectinase enzymes.31. The method of claim 23 , wherein the second extraction liquid is free of added pectinase enzymes.32. The method of claim 23 , wherein the fruit is a proanthocyanidin-containing cranberry.33. The method of claim 23 , ...

COMPOSITION FOR USE IN THE TREATMENT OF INTESTINAL ALTERATIONS

The present invention relates to a composition which comprises a mixture which comprises or, alternatively, consists of an extract (a) of a fruit of at least one plant of the genus and at least one ingredient (b) acceptable for pharmaceutical or food use and the use thereof in the prevention and/or treatment of diverticular disease or of a pathology deriving therefrom or correlated thereto. 1. A composition for oral administration (CR) which comprises , or alternatively consists of:{'i': 'Vaccinium', '(i) a core comprising, or, alternatively, consisting of an extract (a) of at least one plant of the genus and at least one ingredient (b) acceptable for pharmaceutical or food use;'}(ii) a gastro-resistant layer external to the core (i) and which completely coats (i) and comprises at least one ingredient (c) acceptable for pharmaceutical or food use, wherein said gastro-resistant layer (ii) is capable of enabling the release of the extract (a) in the colon; wherein said composition is for use in the prevention and/or treatment of colonic diverticulosis, pathologies or diseases linked to the presence of diverticula, selected from among diverticular disease, SUDD (symptomatic uncomplicated diverticular disease) and colonic diverticulitis.2Vaccinium. The composition according to claim 1 , wherein said extract (a) of at least one plant of the genus is preferably a dry extract present in an amount comprised from 150 mg to 600 mg claim 1 , relative to the total weight of (a).3. The composition according to claim 2 , wherein said extract (a) is present in an amount comprised from 200 mg to 300 mg claim 2 , relative to the total weight of (a) claim 2 , and contains from 80% to 99% proanthocyanidins by weight claim 2 , relative to the total weight of (a).4. The composition according to any one of the preceding claims claim 2 , wherein said extract (a) is preferably a dry extract of cranberry claim 2 , preferably containing PACs (proanthocyanidins) in a concentration of 5% to 30 ...

AQUEOUS IONIC SOLUTION, MADE FROM DISSOLVED MINERAL SALTS, IN PARTICULAR INTENDED FOR THROAT CARE

An aqueous ionic solution based on dissolved mineral salts, in particular intended for throat care, especially for the treatment, prevention and relief of manifestations related to sore throats. The aqueous ionic solution includes: by way of aqueous solvent, at least 20% by weight, with respect to the total weight of the composition, of a hypertonic solution of mineral salts having an osmolality greater than 350 mOsm/kg; at least 50% of one or more polyols of plant origin, by weight with respect to the total weight of the ionic solution,; at least one sucrose and C8-C24 fatty acid ester, by weight with respect to the total weight of the ionic solution; and a non-alcoholic extract of propolis and/or between 1% and 8% honey, by weight with respect to the total weight of the ionic solution. 1. Aqueous anionic solution , in particular intended for throat care , comprising:by way of aqueous solvent, at least 20% by weight, with respect to the total weight of the composition, of a hypertonic solution of mineral salts having an osmolality greater than 350 mOsm/kg,at least 50% of one or more polyols of plant origin, by weight with respect to the total weight of the ionic solution,at least one sucrose and C8-C24 fatty acid ester, by weight with respect to the total weight of the ionic solution,an extract of propolis and/or honey.2. The aqueous ionic solution according to claim 1 , wherein it comprises between 20% and 40% by weight with respect to the total weight of the ionic solution claim 1 , of said hypertonic solution of mineral salts having an osmolality greater than 350 mOsm/kg.3. The Aqueous ionic solution according to claim 1 , wherein the mineral salt solution is a solution based on diluted or non-diluted seawater or a saline solution containing between 22 and 25 g/l claim 1 , of dissolved mineral salts of sodium claim 1 , chlorine claim 1 , sulfate claim 1 , magnesium claim 1 , calcium and potassium.4. The aqueous ionic solution according to claim 1 , wherein it ...

Oral Antagonist Compositions For Nicotine Burning Relief

The invention relates to oral analgesic compositions for alleviation of perceived nicotine irritation through inhibition or blocking of nicotine activated receptors or ion channels in the gastrointestinal tract, including the oral cavity. The composition of the invention comprises one or more nicotine sources, one or more buffering agents, and at least two antagonists in an effective amount to inhibit or block nicotine agonist activation of Nicotinic Acetylcholine Receptors (nAChR) and/or Transient Receptor Potential (TRP) ion channels, the at least two antagonists being selected from the group consisting of a first antagonist comprising camphor or one or more compounds resembling camphor, a second antagonist comprising eucalyptol, and a third antagonist comprising (1R,2S,5R)—N-(4-Methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide (WS-12).

Natural Pet Treat and Method of Production

The invention disclosed herein is directed to a pet treat composition and the method of producing such a composition. The pet treat comprises a mixture of whole wheat flour, blueberries, cinnamon, vanilla yogurt, and almond milk. The composition includes organic and natural ingredients and contains a high level of antioxidants, which provides anti-inflammatory properties that help prevent joint and hip pain. Additionally, the composition contains probiotics that enhance digestive function. When consumed, the probiotics have shown to help the chemical balance and reduce tearing as well as the bacteria that causes tear stains. The present method generally involves mixing all of the ingredients together to form a dough and baking the dough. The composition is suitable for daily consumption and as supplement to a pet's existing diet regimen. 1) A pet treat composition adapted to reduce inflammation , consisting essentially of:whole wheat flour in an amount of approximately 42.2% by weight;frozen blueberries in an amount of approximately 15.0% by weight;cinnamon in an amount of approximately 0.1% by weight;yogurt in an amount of approximately 21.6% by weight;almond milk in an amount of approximately 21.1% by weight;wherein said whole wheat flour, said frozen blueberries, said cinnamon, said yogurt, and said almond milk are mixed together to form a dough;wherein said dough is baked.2) The pet treat composition of claim 1 , wherein said yogurt is vanilla flavored.3) A method of preparing a pet treat claim 1 , comprising the steps of:blending frozen blueberries, cinnamon, yogurt; and almond milk at a room temperature to create a smooth mixture;combining said smooth mixture to whole wheat flour;mixing said smooth mixture and said whole wheat flour to create a dough;rolling said dough into a thin sheet;cutting out said dough into desired shapes;baking said dough.4) The method of preparing a pet treat of claim 3 , wherein said room temperature is 62 degrees to 73 degrees ...

COMPOSITION FOR USE IN THE TREATMENT OF INTESTINAL ALTERATIONS

The present invention relates to a composition which comprises a mixture which comprises or, alternatively, consists of an extract (a) of a fruit of at least one plant of the genus and at least one ingredient (b) acceptable for pharmaceutical or food use and the use thereof in the prevention and/or treatment of diverticular disease or of a pathology deriving therefrom or correlated thereto. 1. A composition for oral administration which comprises:{'i': Vaccinium macrocarpon', 'Vaccinium oxycoccos, '(i) a core comprising an extract of or , or a mixture thereof, wherein the extract contains at least 10% proanthocyanidins by weight, and at least one ingredient (b) acceptable for pharmaceutical or food use; and'}(ii) a gastro-resistant layer external to the core and which completely coats the core and comprises at least one ingredient acceptable for pharmaceutical or food use, wherein said gastro-resistant layer comprises:(a) ethyl cellulose, sodium alginate, purified stearic acid, and ammonium hydroxide; or(b) triethyl citrate, talcum, and one or more of Eudragard® biotic, poly(methyl acrylate-co-methyl methacrylate-co-methacrylic acid) 7:3:1, or another anionic methacrylate copolymerin.2. The composition according to claim 1 , wherein said extract is a dry extract present in an amount from 150 mg to 600 mg.3. The composition according to claim 2 , wherein said extract is present in an amount from 200 mg to 300 mg claim 2 , and contains from 80% to 99% proanthocyanidins by weight.4. The composition according to claim 1 , wherein said extract is a dry extract of cranberry containing PACs (proanthocyanidins) in a concentration of 10% to 30% by weight or volume.5. The composition according to claim 1 , wherein said gastro-resistant layer external to the core breaks down and dissolves as a function of the pH value and/or time.6. The composition according to claim 1 , wherein said gastro-resistant layer external to the core comprises:a gastro-resistant polymer, such as poly ...

ORAL AND INTESTINAL HEALTH PRODUCTS

In various implementations, one or more compositions may be provided to improve or maintain oral and/or intestinal health. For example, a dental powder, toothpaste, mouthwash, and/or probiotic composition may be administered to improve or maintain oral and/or intestinal health. In some implementations, an intestinal health kit that includes cleanse compositions, renewal compositions, and/or digestion aids (e.g., enzymes) may be administered to improve or maintain intestinal health and/or fitness. 1. A method of orally administering one or more compositions to improve or maintain gastrointestinal health of an individual , method comprising: magnesium sulfate; and', 'fruit juice, and wherein the fruit e comprises blueberry juice; and, 'orally administering one or more cleanse compositions, wherein at least one of the cleanse compositions comprisesorally administering one or more renew compositions after administration of the one or more cleanse compositions, wherein at least one of the renew compositions comprises fiber and probiotic,wherein administration of the one or more renew compositions after the administration of the one or more cleanse compositions improves or maintains gastrointestinal health of an individual.2. The method of wherein the at least one cleanse composition comprises green tea.3. The method of wherein the at least one of the cleanse compositions comprises approximately 20 to approximately 40 cc of Magnesium sulfate.4. The method of wherein the fruit juice further comprises grape juice.5. The method of wherein the at least one of the cleanse compositions comprises approximately 20 to approximately 40 cc of Magnesium sulfate claim 1 , approximately 4 to approximately 5 ounces of the fruit juice.6. The method of wherein the at least one of the cleanse compositions further comprises approximately 3/16 to approximately ¼ teaspoon of sweetener.7. The method of wherein the fiber of the renew composition comprises blueberry fiber claim 1 , and wherein ...

FLAVONOID COMPOSITIONS AND METHODS OF USE

Flavonoid compositions containing the flavonoid quercetin and/or derivatives of quercetin are disclosed. The flavonoid compositions are formulated to improve the bioavailability of quercetin. Also provided herein are methods for improving athletic performance, improving cardiovascular health, and aiding in immune response and methods of improving athletic performance, improving bone health, preventing fatigue, reducing recovery time after exercise, countering oxidative stress, and/or boosting energy. 1. A flavonoid composition , comprising:quercetin, the quercetin selected from the group consisting of aglycone quercetin, quercetin glycoside, and isoquercetin; anda second ingredient selected from the group consisting of green tea extract, blueberry anthocyanidins, caffeine and n3-polyunsaturated fatty acids (N3-PUFA).2. The flavonoid composition of claim 1 , comprising:33.9% (w/w) Blueberry Extract;7.9% (w/w) caffeine;12.6% (w/w) vitamin C;13.6% (w/w) green tea extract;15.1% (w/w) omega-3;7.9% (w/w) quercetin; and9.0% ascorbyl palmitate.3. An oral ingestible medicament claim 1 , comprising:a flavonoid;an antioxidant;an anthocyanidin;a stimulant;a lipid;ascorbic acid;an omega 3 fatty acid; andascorbyl palmitate.4. The oral ingestible medicament of claim 3 , wherein the flavonoid is present in an amount ranging from about 10-500 mg.5. The oral ingestible medicament of claim 4 , wherein the flavonoid is present in an amount of about 100 mg.6. The oral ingestible medicament of claim 4 , wherein the flavonoid is present in an amount of about 52 mg.7. The oral ingestible medicament of claim 3 , wherein flavonoid is present in an amount of about 10-500 mg; the antioxidant is present in an amount of about 10-500 mg; the anthocyanidins is present in an amount of about 10-500 mg; the stimulant is present in an amount of about 10-500 mg; the lipid is present in an amount of about 10-500 mg; ascorbic acid is present in an amount of about 10-500 mg; the omega 3 fatty acid is ...

HUMAN GASTROINTESTINAL MICROBIOME MODULATING COMPOSITION AND METHODS OF USE

A formulation to increase the ratio of gastrointestinal microbiota in phylum Bacteroidetes to microbiota of Firmicutes phylum preferably includes about 20-60 mg/kg of body weight of fermentable fiber, about 10-30 mg/kg of body weight of beta glucan and about 20-60 mg/kg of body weight of blueberry extracts or any fruit or berry ingredient preparation containing similar phenolics. This formulation is preferably used to control body weight, body composition, and blood glucose regulation, preferably in humans, and is preferably administered orally, preferably twice per day. 1. A gastrointestinal microbiome modulating composition comprising:a) isolated inulin,b) dietary (3-glucan extract, andc) polyphenol compounds.2. The composition of claim 1 , wherein the isolated inulin is at least about 3 g of isolated inulin claim 1 , and wherein the dietary β-glucan extract is at least about 2 g of dietary β-glucan extract.3. The composition of claim 1 , wherein the polyphenol compounds are sourced from blueberry pomace.4. A method of stimulating weight loss in a human patient claim 1 , the method comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'administering a therapeutically effective amount of the gastrointestinal microbiome modulating composition of to a human patient in need thereof,'}wherein said patient loses weight upon administration of said gastrointestinal microbiome modulating composition.5. A method of increasing satiety in a human patient claim 1 , the method comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'administering a therapeutically effective amount of the gastrointestinal microbiome modulating composition of to a human patient in need thereof,'}wherein said patient exhibits an increase in satiety upon administration of said gastrointestinal microbiome modulating composition.6. A method of improving gastrointestinal health in a human patient through activation of the gastrointestinal immune system claim 1 , the method comprising:{' ...

Morinda Citrifolia Juice Formulations Comprising Iridoids

Embodiments of the invention relate to fortified food and dietary supplement products which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relates to the administration of products enhanced with plant products and iridoids. A study was performed to evaluate the iridoid content, as well as the in vitro and in vivo bioactivities, of a beverage containing noni fruit, Cornelian cherries, and olive leaf extract. The major iridoids present were identified as asperulosidic acid, deacetylasperulosidic acid, oleuropein, morroniside, loganic acid, and loganin In the 2,2-Diphenylpicrylhydrazyl (DPPH) radical scavenging assay, remarkably high in vitro antioxidant activity was observed, with an ICof 3.8 μL/mL. In vivo bioactivities were evaluated in type 2 diabetic Sprague Dawley rats. In a dose-dependent manner, the composition reduced abnormal weight gain, blood glucose levels, and serum advanced glycation end products (AGEs), as well as improved immunity via increased T cell counts and CD4+/CD8 ratios. 1. A formulation comprising , by weight of the formulation:{'i': 'Morinda citfrifolia', 'fruit juice in an amount by weight between about 10 and 75 percent;'}{'i': 'Malus pumila', 'juice concentrate in an amount by weight between 10 and 75 percent;'}{'i': 'Mangifera indica', 'juice concentrate in an amount by weight between 5 and 50 percent;'}{'i': 'Passiflora edulis', 'juice concentrate in an amount by weight between 3 and 30 percent;'}oligofructose in an amount by weight between 0.1 and 15 percent;fructose in an amount by weight between 0.1 and 15 percent;vegetable protein isolate in an amount by weight between 0.1 and 15 percent; andnatural flavor in an amount by weight between 0.1 and 5 percent.2. The formulation of claim 1 , further comprising:xanthum gum in an amount by weight between 0.1 and 15 percent; andgum Arabic in an amount by weight between 0.1 and 15 percent.3. The formulation of claim 1 , further ...

Multi-nutrient supplement and uses thereof

Various embodiments of the invention relate to compositions comprising vitamins, minerals and trace elements, antioxidants, amino acids, probiotics, and other components and methods for using such compositions to treat or prevent diseases associated with oxidative stress, including cardiovascular disease.

Botanical Antioxidants

A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the leaf of a plant from the genus 1Vaccinium macrocarpon. A composition comprising the botanical extract of the leaf of , wherein the botanical extract inhibits γ-H2AX activity.2. The composition according to claim 1 , wherein the botanical extract is present in an amount of about 1.0 μg/mL or greater.3. The composition according to claim 2 , wherein the botanical extract is present in an amount of about 1.0 μg/mL to about 1000.0 μg/mL.4. A dietary supplement having antioxidant properties comprising a cranberry leaf extract in a therapeutically effective amount claim 2 , wherein the cranberry leaf extract inhibits γ-H2AX activity.5. The dietary supplement according to claim 4 , wherein the cranberry leaf extract is present in an amount of about 25.0 μg/mL claim 4 , to about 500.0 μg/mL.6Vaccinium macrocarpon. A method of inhibiting oxidation-induced DNA damage in a subject comprising administering a composition comprising the botanical extract of the leaf of at a concentration of about 1.0 μg/mL to about 1000.0 μg/mL. The present application claims the benefit of U.S. Patent Application No. 62/728,113, filed 7 Sep. 2018, the disclosure of which is incorporated herein in its entirety by reference.The present invention generally relates to inhibitors of oxidation-induced DNA damage, and more particularly to botanical inhibitors of oxidation-induced DNA damage, namely, cranberry () leaves, and the use of such plant-based inhibitors as an antioxidant.Oxygen is a highly reactive atom that is capable of becoming part of potentially damaging molecules called “free radicals”. Free radicals, commonly known as reactive oxygen species (‘ROS’), contain one or more unpaired electrons in their outermost orbital. Common examples of reactive oxygen species include peroxyl radical (ROO), superoxide anion (O), reactive hydroxyl (OH), and hydrogen peroxide (HO) radicals. ...

Botanical Modulator of Metabolic Disorders

Plant-based inhibitors of MMP-9 that also function as PPAR-γ agonists, and the use of such plant-based inhibitors/agonists in modulating metabolic disorders is disclosed. The plant-based inhibitor/agonist is at least an extract obtained from the leaf of the genus 1Vaccinium macrocarpon. A composition comprising the botanical extract of the leaf of , wherein the botanical extract exhibits modulation of one or more metabolic disorders.2. The composition according to claim 1 , wherein the botanical extract is present in an amount of about 1.0 μg/mL or greater.3. The composition according to claim 2 , wherein the botanical extract is present in an amount of about 1.0 μg/mL to about 2000.0 μg/mL.4. The composition according to claim 1 , wherein the composition further exhibits MMP-9 inhibition.5. The composition according to claim 4 , wherein the botanical extract is present in an amount of about 1.0 μg/mL to about 2000.0 μg/mL.6. The composition according to claim 1 , wherein the composition further exhibits PPAR-γ agonist activity.7. The composition according to claim 6 , wherein the botanical extract is present in an amount of about 50.0 μg/mL to about 2000.0 μg/mL.8Vaccinium macrocarpon. A dietary supplement having modulatory properties for one or more metabolic disorders comprising the botanical extract of the leaf of in a therapeutically effective amount.9Vaccinium macrocarpon. The dietary supplement according to wherein the botanical extract of the leaf of is present in an amount of about 1.0 μg/mL or greater.10Vaccinium macrocarpon. A method of modulating one or more metabolic disorders in a subject comprising administering a composition comprising the botanical extract of the leaf of at a concentration of about 1.0 μg/mL to about 2000.0 μg/mL. The present application claims the benefit of U.S. Patent Application No. 62/728,119, filed 7 Sep. 2018, the disclosure of which is incorporated herein in its entirety by reference.The present invention generally relates ...

Anti-Inflammatory Botanical Extract

A botanical extract that exhibits anti-inflammatory activity, wherein the botanical extract is at least an extract from the leaf of 1Vaccinium macrocarpon. A composition comprising the botanical extract of the leaf of , wherein the botanical extract exhibits anti-inflammatory activity.2. The composition according to claim 1 , wherein the botanical extract is present in an amount of about 1.0 μg/mL or greater.3. The composition according to claim 2 , wherein the botanical extract is present in an amount of about 1.0 μg/mL to about 2000.0 μg/mL.4. The composition according to claim 3 , wherein the botanical extract is present in an amount of about 50.0 μg/mL to about 500.0 μg/mL.5. The composition according to claim 1 , wherein the composition inhibits COX-1 activity.6. The composition according to claim 5 , wherein the botanical extract is present in the composition in an amount of about 50.0 μg/mL to about 500.0 μg/mL.7. The composition according to claim 1 , wherein the composition inhibits COX-2 activity.8. The composition according to claim 7 , wherein the botanical extract is present in the composition in an amount of about 30.0 μg/mL to about 500.0 μg/mL.9. The composition according to claim 1 , wherein the composition inhibits 5-LOX activity.10. The composition according to claim 9 , wherein the botanical extract is present in the composition in an amount of about 60.0 μg/mL to about 250.0 μg/mL11. The composition according to claim 1 , wherein the composition inhibits COX-1 activity claim 1 , COX-2 activity claim 1 , and 5-LOX activity.12. The composition according to further comprising a pharmaceutically acceptable carrier.13. The composition according to wherein the composition is a dietary supplement.14. The composition according to wherein the composition is a topical composition.15. A dietary supplement having anti-inflammatory properties comprising a cranberry leaf extract in a therapeutically effective amount.16Vaccinium macrocarpon. A method of ...

Emulsion of Carotenoids and Ocular Antioxidants

A daily liquid supplement for ocular and body health containing at least one of lutein, zeaxanthin, meso-zeaxanthin and astaxanthin for a human subject for nutritionally supplementing macular pigments is disclosed. The micronized nutrients in a lipid based emulsion are more efficiently absorbed into the bloodstream than conventional supplement formulations resulting in higher serum levels and increased macular pigment. 2. The formulation of wherein said wetting agent is a partially hydrolyzed de-oiled lecithin.3. The formulation of wherein the partially hydrolyzed de-oiled lecithin is derived from soy.4. The formulation of wherein said emulsifier is a polyethylene glycol sorbitan fatty acid mono-ester.5. The formulation of wherein said emulsifier is polysorbate 80.6. The formulation of wherein said stabilizer is selected from the group of natural gums consisting of pectin claim 1 , xanthan claim 1 , alginate claim 1 , and guar gum.7. The formulation of wherein said stabilizer is xanthan gum.8. The formulation of wherein said aqueous solvent including water claim 1 , a buffering agent claim 1 , and a co-solvent for lowering interfacial tension of the aqueous phase and enhancing the activity of said wetting agent with respect to dispersal of said hydrophobic carotenoid within said aqueous solvent claim 1 , the co-solvent being selected from the group consisting of an alcohol and a polyol.9. The formulation of wherein the co-solvent is glycerin.10. The formulation of wherein the buffering agent is a salt of citric acid.11. The formulation of wherein the water is purified by reverse osmosis.12. The formulation of further comprising a natural flavor and a sweetening agent.13. The formulation of lacking contact with an edible encapsulation material.14. The formulation of further comprising a water soluble nutritional supplement selected from the group consisting of acetyl-L carnitine claim 1 , biotin claim 1 , coenzyme Q10 claim 1 , folic acid claim 1 , L-taurine claim 1 ...

METHOD TO PREPARE A THERAPEUTIC BALM

A method to prepare a therapeutic balm is disclosed. A first phase solution is prepared in an oak barrel using a grain neutral spirit. The first phase is mixed for 10 minutes per day for a month to prepare a second phase solution. The second phase solution is filtered at least twice to prepare a filtrate. The filtrate and third phase components are mixed to prepare a third phase solution. The third phase solution is mixed with a distilled wine liquor to prepare a fourth phase solution. The fourth phase solution is mixed at least twice a day for a month to prepare a fifth phase solution. The fifth phase solution is mixed with cranberry juice, pomegranate juice, and raspberry juice to prepare a sixth phase solution. The sixth phase solution is stored in a ceramic bottle for a least six months at room temperature to prepare a therapeutic balm.

SUBSTANCE FOR RESTORING NORMAL CO-EXPRESSION AND INTERACTION BETWEEN THE LOX AND NRAGE PROTEINS

The invention relates to the use of a substance for restoring normal co-expression and interaction between the LOX and NRAGE proteins. The invention relates in particular to the use of an effective amount of at least one substance that modulates the expression and/or activity of the LOX of SEQ ID NO: 1 and/or that modulates the expression and/or activity of the NRAGE of SEQ ID NO: 2 for modulating the interaction between the LOX and NRAGE proteins to regulate the balance between the cellular proliferation, differentiation and apoptosis, particularly in cases where the balance between these phenomena is disturbed, and especially in cases where the interaction between LOX and NRAGE is absent or altered. The invention makes it possible to treat skin ageing, lichen planus, graft-versus-host reaction (GVH), eczema, psoriasis and a cancer, particularly an epithelial cancer and more particularly a cutaneous epithelial cancer of basocellular or spinocellular type. 1. A method for regulating balance between cellular proliferation , differentiation and apoptosis in epithelial cells , comprising applying a pharmaceutical or cosmetic composition onto an epidermis in need thereof , wherein said composition comprises an effective amount of:i) at least one active ingredient that modulates expression of the lysyl oxidase (LOX) having the amino acid sequence of SEQ ID NO: 1;ii) at least one active ingredient that modulates expression of the NRAGE having the amino acid sequence of SEQ ID NO: 2; oriii) a combination of the active ingredient of i) and the active ingredient of ii).2. The method of claim 1 , wherein the epithelial cells are keratinocytes.3. The method of claim 2 , wherein the active ingredient of i) increases the expression of the lysyl oxidase by about 50% in the keratinocytes.4. The method of claim 2 , wherein the active ingredient of i) decreases the expression of the lysyl oxidase by about 50% in the keratinocytes.5. The method of claim 2 , wherein the active ...

HEART-PROTECTIVE PLANT PREPARATION FOR PREVENTING AND IMPROVING CORONARY HEART DISEASE

The present disclosure provides a natural plant preparation, including extracts of the following parts of plants: roots of Bunge, L. and Rosc., barks of Presl, seeds of L., L. and L., leaves of L., resin of drupes of L., beans of L., dried pulp and kernels of L., dried pulp of Linn., Walnut and Spp, cloves of and petals of sp. The present disclosure further provides a method for preparing a plant preparation, including treating the above parts of plants with ethanol. 1Salvia miltiorrhizaJuglans regia, Aesculus hippocastanumZingiber officinaleCinnamomum cassiaSesamum indicum, Carica papayaNigella damascenaPunica granatumCentaurea cyanusPistacia Lentiscus,Cocos nuciferaTheobroma cacaoPhoenix dactyliferaOlea europaea, Ficus caricaVacciniumAllium sativum,Rosa. A plant preparation for preventing and controlling various coronary heart disease risk factors , comprising ethanol extracts of following parts of plants: roots of Bunge , L. and Rosc. , barks of Presl , seeds of L. , L. and L. , leaves of L. , resin of drupes of L. , beans of L. , dried pulp and kernels of L. , dried pulp of Linn. , Walnut and Spp , cloves of and petals of sp.2. (canceled)3. The plant preparation according to claim 1 , comprising ethanol extracts of the following parts of plants:{'i': 'Salvia miltiorrhiza', '15-25 parts by weight of roots of Bunge,'}{'i': 'Juglans regia,', '5-15 parts by weight of roots of'}{'i': 'Aesculus hippocastanum', '15-25 parts by weight of roots of L.,'}{'i': 'Zingiber officinale', '5-15 parts by weight of roots of Rosc.,'}{'i': 'Cinnamomum cassia', '5-15 parts by weight of barks of Presl,'}{'i': 'Sesamum indicum,', '5-15 parts by weight of seeds of'}{'i': 'Carica papaya', '5-15 parts by weight of seeds of L.,'}{'i': 'Nigella damascena', '15-25 parts by weight of seeds of L.,'}{'i': 'Punica granatum', '5-15 parts by weight of seeds of L.,'}{'i': 'Centaurea cyanus', '15-25 parts by weight of leaves of L.,'}{'i': 'Pistacia Lentiscus,', '5-15 parts by weight of resin of'}{'i ...

Prevention of Pathological Coagulation in COVID-19 and other Inflammatory Conditions

The invention is directed to the utilization of pterostilbene, and/or nigella sativa extract, and/or sulforaphane, and/or Epigallocatechin gallate (EGCG) alone or in combination, for the prevention of pathological coagulation. In on embodiment a composition containing all four ingredients is administered to a patient at risk of hypercoagulation in order to prevent aberrant expression of pro-coagulation molecules and/or induce expression of molecules known to suppress coagulation. In one embodiment the invention teaches administration of pterostilbene, thymoquinone, sulforaphane, and EGCG as a means of decreasing expression of tissue factor. 1. A method of reducing inflammation associated hypercoagulation states comprising administration of a therapeutic combination comprising: a) Green Tea and/or extract thereof; b) Blueberry and/or extract thereof; c) Nigella Sativa and/or extract thereof; and d) broccoli and/or extract thereof.2. The method of claim 1 , wherein said green tea extract is epigallocatechin-3-gallate or an analogue thereof.3. The method of claim 1 , wherein said blueberry extract is pterostilbene or an analogue thereof.4. The method of claim 1 , wherein said Nigella Sativa extract is thymoquinone or an analogue thereof.5. The method of claim 1 , wherein said broccoli extract is sulforaphane or an analogue thereof.6. The method of claim 1 , wherein said therapeutic combination is administered at a dosage and frequency sufficient to inhibit tissue factor expression.7. The method of claim 6 , wherein said tissue factor expression is on the endothelium.8. The method of claim 6 , wherein said tissue factor expression is on microglia.9. The method of claim 6 , wherein said tissue factor expression is on the monocytes.10. The method of claim 6 , wherein said tissue factor expression is on pulmonary endothelium.11. The method of claim 6 , wherein said tissue factor expression is on the renal endothelium.12. The method of claim 1 , wherein said therapeutic ...

STABILIZED ANTHOCYANIN COMPOSITIONS

The invention describes stabile anthocyanin compositions, methods to prepare such compositions and also methods of use of such compositions to treat various afflictions. The present invention describes unique compositions of an anthocyanin and a stabilizing compound such that the combination of the two components provides that the anthocyanin does not readily undergo degradation, such as oxidation, pH instability, etc. 1. A composition comprising:a blueberry material and cysteine.2. The composition of claim 1 , wherein the blueberry material is selected from whole fruit claim 1 , juice or extract.3. The composition of claim 1 , wherein the blueberry material is a dried material.4. The composition of claim 3 , wherein the dried material is a particulate or a powder.5. The composition of claim 1 , wherein the weight ratio of cysteine to blueberry material is from about 0.1 to about 10.6. The composition of claim 5 , wherein the weight ratio of cysteine to blueberry material is from about 2 to about 10.7. The composition of claim 1 , wherein the composition is stable toward degradation when exposed to an aqueous environment with a pH of between about 2 and about 12.8. The composition of claim 7 , wherein the composition is stable toward degradation when exposed to an aqueous environment with a pH of about 7. This application is a continuation of U.S. application Ser. No. 13/801,175, filed on Mar. 13, 2013, which is a continuation-in-part of U.S. application Ser. No. 13/442,455 filed on Apr. 9, 2012, now U.S. Pat. No. 8,449,927, issued May 28, 2013, which is a continuation of U.S. application Ser. No. 12/825,546 filed on Jun. 29, 2010, now U.S. Pat. No. 8,153,168, issued on Apr. 10, 2012, which is a continuation of U.S. application Ser. No. 12/047,993 filed on Mar. 13, 2008, now U.S. Pat. No. 7,820,207 issued on Oct. 26, 2010, which claims benefit of U.S. Provisional Application No. 60/895,034 filed on Mar. 15, 2007, U.S. Provisional Application No. 60/952,113 filed on ...

COMPOSITIONS AND METHODS FOR CONTROLING CARBOHYDRATE AND FAT METABOLISM

The subject of the invention is a composition comprising at least a mixture of molecules obtained at least from: 2. The composition of claim 1 , wherein the mixture of molecules consists at least of:{'i': 'Chrysanthellum indicum,', 'an extract of'}{'i': 'Cynara scolymus,', 'an extract of'}{'i': 'Vaccinium myrtillus', 'an extract of , and'}{'i': 'Piper', 'synthetic piperine and/or an extract of containing piperine.'}3. The composition of claim 1 , wherein the mixture of molecules consists at least of:{'i': Chrysanthellum indicum, Cynara scolymus', 'Vaccinium myrtillus', 'Piper,, 'a single extract obtained from at least and and'}{'i': Chrysanthellum indicum, Cynara scolymus', 'Vaccinium myrtillus, 'a single extract obtained from at least and ; and'}synthetic piperine.4Olea europaea.. The composition of claim 1 , wherein the mixture of molecules further comprises molecules obtained from5Olea europaeaOlea europaea.. The composition of claim 4 , wherein the mixture of molecules also comprises an extract of and/or in that the single extract(s) are also obtained from6PiperPiper nigrum, Piper aduncumPiper longum.. The composition of claim 2 , wherein the is chosen from and7Chrysanthellum indicumChrysanthellum indicum. The composition of claim 1 , wherein at least one of the extract of and the single extract(s) are obtained from whole plant and/or aerial parts.8Cynara scolymusCynara scolymus. The composition of claim 1 , wherein at least one of the extract of and the single extract(s) are obtained from whole plant and/or leaves.9Vaccinium myrtillusVaccinium myrtillus. The composition of claim 1 , wherein at least one of the extract of and the single extract(s) are obtained from whole plant and fruit.10. The composition of claim 1 , wherein the composition has at least one of the following characteristics:{'i': Chrysanthellum indicum', 'Chrysanthellum indicum, 'It comprises an amount of extract of allowing the administration of at least 0.00001 g of extract of per kg of body ...

CONPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CANCER

Compositions comprising biotransformed fruit extracts and methods of using the compositions in the prevention and treatment of cancer are provided. The fruit extracts are biotransformed by fermentation with a bacterial strain having all the identifying characteristics of . The compositions can be used to inhibit tumour growth, tumour metastasis and cancer stem cell (CSC) development. 145.-. (canceled)46Serratia vaccinii.. A method of inhibiting cancer stem cell development in a subject comprising administering to the subject an effective amount of a composition comprising a biotransformed fruit extract , wherein the biotransformed fruit extract is prepared by fermenting a fruit extract with a bacterial strain having all the characteristics of47. (canceled)48. The method according to claim 46 , wherein the inhibition of cancer stem cell development inhibits cancer metastasis in the subject.4950.-. (canceled)51. The method according to claim 46 , wherein the cancer is brain cancer claim 46 , breast cancer claim 46 , colon cancer claim 46 , ovarian cancer claim 46 , pancreatic cancer claim 46 , prostate cancer claim 46 , liver cancer claim 46 , bladder cancer claim 46 , melanoma or multiple myeloma.52. The method according to claim 46 , wherein the cancer is breast cancer claim 46 , prostate cancer or melanoma.53Vaccinium.. The method according to claim 46 , wherein the fruit extract is from one or more berries from the genus5457.-. (canceled)58. The method according to claim 46 , wherein the biotransformed fruit extract is characterized as having a total phenolic content at least two times greater than untransformed fruit extract.59. The method according to claim 46 , wherein the composition is administered orally to the subject.60. The method according to claim 46 , wherein the composition is formulated as a pharmaceutical composition claim 46 , a nutraceutical claim 46 , a dietary supplement claim 46 , a cosmetic preparation claim 46 , a functional food or a ...

COMBINATION OF A URINARY ACIDIFIER AND A CALCIUM PHOSPHATE CRYSTALLISATION INHIBITOR FOR THE TREATMENT OR PREVENTION OF RENAL LITHIASIS

The present invention is related to the use of a separate, sequential or simultaneous combination of at least one urinary acidifier with at least one calcium phosphate crystallization inhibitor for urine acidification, and thus preventing the pH at which supersaturation of calcium phosphate is produced and consequently, renal lithiasis. 1. Use of a preparation comprising at least one urinary acidifier combined sequentially , simultaneously or separately with at least one calcium phosphate crystallization inhibitor , in the manufacture of a medicament.2. Use of a preparation comprising at least one urinary acidifier combined sequentially , simultaneously or separately with at least one calcium phosphate crystallization inhibitor , in the manufacture of a medicament for the treatment or prevention of renal lithiasis.3Vaccinum. The use according to wherein the urinary acidifier is selected from a portion or an extract of the plant species claim 1 , pharmaceutically acceptable ammonium salts claim 1 , arginine or any of its pharmaceutically acceptable salts claim 1 , cysteine or any of its pharmaceutically acceptable salts claim 1 , phenazopyridine or any of its pharmaceutically acceptable salts claim 1 , methionine or any of its pharmaceutically acceptable salts or mixtures thereof.4. The use according to wherein the urinary acidifier is selected from cranberry claim 3 , ammonium chloride claim 3 , L-arginine claim 3 , L-cysteine or mixtures thereof.5. The use according to wherein the crystallization inhibitor is phytic acid or any of its pharmaceutically acceptable salts.6. The use according to wherein the pharmaceutically acceptable salts of phytic acid are selected from sodium phytate claim 5 , potassium phytate claim 5 , calcium phytate claim 5 , magnesium phytate claim 5 , zinc phytate claim 5 , calcium-magnesium phytate or combinations of the same.7. The use according to wherein phytic acid or its salts are derived from a portion of a plant species rich in phytic ...

FLAVONOID COMPOSITIONS AND METHODS OF USE

Flavonoid compositions containing the flavonoid quercetin and/or derivatives of quercetin are disclosed. The flavonoid compositions are formulated to improve the bioavailability of quercetin. Also provided herein are methods for improving athletic performance, improving cardiovascular health, and aiding in immune response and methods of improving athletic performance, improving bone health, preventing fatigue, reducing recovery time after exercise, countering oxidative stress, and/or boosting energy. 1. A chewable tablet , comprising:quercetin;bilberry extract;green tea leaf extract; andone or more of vitamin C, caffeine, or omega 3 fatty acids.2. A chewable tablet , comprising:vitamin C;wild bilberry fruit extract;green tea leaf extract;quercetin aglycone;caffeine; andomega 3 fatty acids.3. The chewable tablet of claim 2 , wherein vitamin C is present as ascorbyl palmitate.4. The chewable tablet of claim 2 , wherein vitamin C is present in an amount of about 100 mg.5. The chewable tablet of claim 2 , wherein the wild bilberry fruit extract comprises about 25% total anthocyanins.6. The chewable tablet of claim 2 , wherein the green tea leaf extract comprises about 50% epigallocatechin 3-gallate (EGCG).7. The chewable tablet of claim 2 , wherein the omega 3 fatty acids comprise n3 polyunsaturated fatty acids (n3-PUFA).8. The chewable tablet of claim 7 , wherein the n3-PUFA is present in an amount of about 60 mg.9. The chewable tablet of claim 7 , wherein the n3-PUFA comprises docosahexaenoic acid and eicosapentaenoic acid.10. The chewable tablet of claim 9 , wherein the docosahexaenoic acid is present in an amount of about 24 mg.11. The chewable tablet of claim 9 , wherein the eicosapentaenoic acid is present in an amount of about 36 mg.12. The chewable tablet of claim 2 , wherein the caffeine is present in an amount of about 107 mg.13. The chewable tablet of claim 2 , wherein the composition comprises about 329 mg of total flavonoids in aglycone form.14. The ...

SYSTEMS AND METHODS FOR THROMBOSIS PREVENTION

The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E. 1. A method of treating or preventing venous thrombosis in a subject in need thereof , the method comprising administering to the subject a composition comprising eicosapantaenoic acid (EPA).2. The method of claim 1 , wherein the composition contains a dose of EPA in the range of 240 mg to 1000 mg.3. The method of claim 1 , wherein the subject is administered 1 gram to 2 grams of EPA per day.4. The method of claim 1 , further comprising administering Vitamin E to the subject.5. The method of claim 4 , wherein the subject is administered 1 mg to 1 gram of Vitamin E per day.6. The method of claim 5 , wherein the subject is administered 15 mg to 100 mg of Vitamin E per day.7. The method of claim 1 , wherein the composition further comprises an antioxidant.8. The method of claim 7 , wherein the antioxidant comprises Vitamin E.9. The method of claim 1 , further comprising administering aspirin to the subject.10. The method of claim 9 , wherein the subject is administered up to 325 mg of aspirin twice per day.11. The method of claim 1 , wherein the composition is at least one of a tablet claim 1 , capsule claim 1 , food claim 1 , powder claim 1 , gummy claim 1 , quick melt tablet claim 1 , and an intravenous injection.12. The method of claim 1 , wherein the venous thrombosis is deep vein thrombosis (DVT).13. The method of claim 1 , wherein the subject is at risk for venous thrombosis.14. The method of claim 13 , wherein the subject at risk for venous thrombosis is selected from the group consisting of surgical patients claim 13 , women who are taking birth control pills or participating in an estrogen regime claim 13 , males who are taking steroid supplements claim 13 , patients who have active cancer claim 13 , patients who have prior incidence of thrombosis claim 13 , ...

COMBINED PREPARATION COMPRISING AN ANTHOCYANIN COMPOSITION AND AN ANTIVIRAL AGENT

Combined preparations including an anthocyanin composition and an antiviral agent for use in treating or preventing a virus infection in a subject, wherein the anthocyanin composition includes an extract of black currants, an extract of bilberries, an extract of red grapes, and/or delphinidin 3 glucoside, wherein the virus is from the Herpesviridae family and the antiviral agent is a Herpesviridae antiviral agent, and wherein the anthocyanin composition and the antiviral agent are for simultaneous, separate or sequential use. 1. A combined preparation , comprising:an anthocyanin composition; andan antiviral agent suitable for treating or preventing a virus infection in a subject,wherein the anthocyanin composition comprises an extract of black currants, an extract of bilberries, an extract of red grapes, and/or delphinidin 3 glucoside (D3G),wherein the virus is from the Herpesviridae family and the antiviral agent is a Herpesviridae antiviral agent, andwherein the anthocyanin composition and the antiviral agent are suitable for simultaneous, separate or sequential use with respect to each other.2. The combined preparation of claim 1 , wherein the anthocyanin composition comprises the extract of black currants and the extract of bilberries.3. The combined preparation of claim 1 , which is a composition comprising the anthocyanin composition and the antiviral agent.4. A method of treating or preventing a virus infection in a subject claim 1 , the method comprising:administering an anthocyanin composition to the subject, either (i) in combination with an antiviral agent active against the virus or (ii) after the antiviral agent is administered to the subject,wherein the anthocyanin composition comprises an extract of black currants, an extract of bilberries, an extract of red grapes, and/or delphinidin 3 glucoside, andwherein the virus is from the Herpesviridae family and the antiviral agent is a Herpesviridae antiviral agent.5. A method of treating or preventing a ...

TREATMENT AND PREVENTION OF INFECTIONS BY HERPESVIRIDAE WITH DELPHINIDIN-3-GLUCOSIDE

The present invention is related to Delphinidin-3-glucoside (D3G) for use in treating or preventing a vims infection in a subject, wherein the virus is from the Herpesviridae family. 1. A method for treating a virus infection , the method comprising:administering Delphinidin-3-glucoside (D3G) to a subject in need thereof, wherein the virus infection is caused by a virus of the Herpesviridae family.2. The method of claim 1 , further comprising:preparing a composition comprising the D3G prior to the administering,wherein the composition is at least one selected from the group consisting of a red grape extract, a bilberry extract, and a black currant extract.3Ribes nigrum. The method of claim 2 , wherein when the composition is a black currant extract claim 2 , black currants of the black currant extract are the fruit of and/or{'i': 'Vaccinium myrtillus.', 'when the composition is a bilberry extract, bilberries of the bilberry extract are the fruit of'}4. The method of claim 1 , wherein the D3G is comprised in a composition claim 1 , and the composition comprises one or more further anthocyanins in addition to the D3G claim 1 , and the D3G is present in the composition in a greater dry weight amount than each of the one or more further anthocyanins.5. The method of claim 1 , wherein the D3G is comprised in an anthocyanin composition consisting essentially of the D3G.6. The method of claim 1 , wherein the administering is topically administering the D3G to the skin claim 1 , lips claim 1 , or eye of the subject.7. The method of claim 1 , wherein the D3G is comprised in a composition claim 1 , and the D3G is present in the composition at a concentration of at least 20 weight-%.8. The method of claim 1 , wherein the virus is herpes simplex virus-1 (HSV-1) claim 1 , herpes simplex virus-2 (HSV-2) claim 1 , Varicella zoster virus (VZV) claim 1 , Epstein-Barr virus (EBV) claim 1 , Cytomegalovirus (CMV) claim 1 , Roseolovirus claim 1 , or Kaposi's sarcoma-associated ...

COMPOSITIONS AND METHODS USEFUL IN TREATMENT OF LOWER URINARY TRACT SYMPTOMS, BENIGN PROSTATIC HYPERPLASIA, ERECTILE DYSFUNCTION, AND OTHER DISEASES OR SYMPTOMS

The invention relates to therapeutic compositions, solid oral dosage forms, and methods for treating, preventing, or alleviating lower urinary tract symptoms (LUTS), benign prostatic hyperplasia (BPH), erectile dysfunction (ED), urinary incontinence, bladder obstruction, overactive bladder (OAB), underactive bladder, interstitial cystitis, prostatitis, bladder and prostate inflammation, prostate fibrosis or pelvic pain. The therapeutic compositions can comprise cranberry powder enriched in cranberry seeds or cranberry seed meal. 1. A therapeutic composition comprising dried cranberry powder and dried cranberry seeds or cranberry seed meal.2Vaccinium macrocarpon, Vaccinium microcarponVaccinium oxycoccus.. The composition of claim 1 , wherein the cranberry is selected from the group consisting of and3. The composition of claim 1 , wherein the cranberry seeds are present in an amount of about 5% to about 50% by weight of the dried cranberry powder.4. The composition of claim 1 , wherein the cranberry seed meal is present n an amount of about 5% to about 50% by weight of the dried cranberry powder.5. The composition of claim 1 , wherein the composition comprises less than about 12% of organic acids by weight.6. The composition of claim 1 , wherein the composition comprises less than about 15% of sugars by weight.7. The composition of claim 1 , wherein the composition comprises from about 1% to about 5% of quinic acid by weight.8. The composition of claim 1 , wherein the composition comprises from about 0.4% to about 4% of malic acid by weight.9. The composition of claim 1 , wherein the composition comprises from about 1% to about 5% of citric acid by weight.10. The composition of claim 1 , wherein the composition comprises: 0.5% to 5.0% proanthocyanidins claim 1 , 0.05% to 1.5% quercetin claim 1 , 0.001% to 0.1% quercetin-3-glucoside claim 1 , 0.001% to 0.1% quercetin-3-rhamnoside claim 1 , 0.001% to 0.1% quercetin-3-xyloside claim 1 , 0.001% to 0.1% quercetin-3- ...