02-01-2020 дата публикации
Номер: US20200002336A1
The invention provides novel compounds having the general formula (I) 3. A compound according to any one of and , wherein Ris selected from the group consisting of{'sub': '1-6', 'sup': 3', '4', '5, 'i) phenyl-C-alkyl substituted by R, Rand R,'}{'sup': 3', '4', '5, 'ii) pyridinyl substituted by R, Rand R, and'}{'sub': '1-6', 'sup': 3', '4', '5, 'iii) pyridinyl-C-alkyl substituted by R, Rand R.'}4. A compound according to any one of and , wherein Ris selected from the group consisting of{'sub': '1-6', 'sup': 3', '4', '5, 'i) phenyl-C-alkyl substituted by R, Rand R, and'}{'sup': 3', '4', '5, 'ii) pyridinyl substituted by R, Rand R.'}5. A compound according to any one of to , wherein Y is selected from the groups consisting ofi) —OC(O)—, andii) —C(O)—.6. A compound according to any one of to , wherein A is selected from the groups consisting ofi) —O—, andii) —S—.7. A compound according to any one of to , wherein A is —O—.8. A compound according to any one of to , wherein X is —N—.9. A compound according to any one of to , wherein W is —C(O)—.10. A compound according to any one of to , wherein Ris selected from the ring systems O , AO and AW.11. A compound according to any one of to , wherein Ris selected from the ring systems O and AO.12. A compound according to any one of to , wherein Ris selected from the groups consisting of{'sub': '1-6', 'i) C-alkylcarbonylamino, and'}{'sub': '1-6', 'ii) tetrahydropyranyl-C-alkoxy.'}13. A compound according to any one of to , wherein Ris selected from the groups consisting ofi) cyano,{'sub': '3-8', 'ii) C-cycloalkyl, and'}{'sub': '1-6', 'iii) halo-C-alkyl.'}14. A compound according to any one of to , wherein Ris selected from the groups consisting ofi) cyano, and{'sub': '3-8', 'ii) C-cycloalkyl.'}15. A compound according to any one of to , wherein Ris selected from the groups consisting ofi) H, andii) halogen.16. A compound according to any one of to , wherein m and n are independently selected from 1 and 2.17. A compound according ...
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