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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 6151. Отображено 100.
29-03-2012 дата публикации

Orthopaedic splinting system

Номер: US20120073584A1
Автор: Antti PÄRSSINEN
Принадлежит: Onbone Oy

A composite material in the form of a linear structure having a width, a length and a thickness, comprising a composite material with a first component formed by a polymer and a second component formed by a reinforcing material, wherein the first component comprises a thermoplastic polymer selected from the group of biodegradable polymers and mixtures thereof, and the second component comprises a woody material derived from platy or granular wood particles. The composite material being formable at a temperature of about 50 to 70° C. and it can be used as a blank for an orthopedic splint.

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Номер записи: 1
19-04-2012 дата публикации

Method of producing composite materials

Номер: US20120090759A1
Автор: Antti PÄRSSINEN, Petro Lahtinen
Принадлежит: Onbone Oy

The invention relates to a method for making light-weight dimensionally stable wood-thermoplastic composite material composed of wood chips and a thermoplastic polycaprolactone. The manufacturing process of composite material comprising the steps of compounding virgin materials with single-screw extruder and production of uniform homogeneous plate-like composite with calendering apparatus. The calendering process comprises of several cycles, folding, cooling and reheating steps. During the gentle manufacturing process fragile wood chips maintain their 3-D structural properties in polymer matrix resulting light, mechanically strong wood-plastic composite.

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Номер записи: 2
24-05-2012 дата публикации

Clay-based hemostatic agents and devices for the delivery thereof

Номер: US20120130296A1
Автор: Daniel J. Burns, Denny Lo, Francis X. Hursey, Giacomo Basadonna, Raymond J. Huey
Принадлежит: Z Medica LLC

A hemostatic device for promoting the dotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

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Номер записи: 3
14-06-2012 дата публикации

Solid dressing for treating wounded tissue

Номер: US20120150087A1
Автор: Dawson Beall, Martin Macphee
Принадлежит: Dawson Beall, MACPHEE Martin

Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of a fibrinogen component and thrombin, wherein the thrombin is present in an amount between 0.250 Units/mg of fibrinogen component and 0.062 Units/mg of fibrinogen component. Also disclosed are methods for treating wounded tissue.

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Номер записи: 4
21-06-2012 дата публикации

Water-Absorbent Surface-Modified-Clay Linked Polymers

Номер: US20120157623A1
Автор: Axel Meyer, Josef Breu, Manuela Stirner, Michael Moeller, Torsten Lindner
Принадлежит: Procter and Gamble Co

An aqueous acidic polymerization liquid comprising polymerisable monomers or oligomers with carboxylate and/or carboxylic acid moiety or moieties, and basal surface modified clay that is homogenously dispersable in said liquid is provided, and also methods for making such liquids, and also surface-modified-clay linked water-absorbing polymers made with said liquids and methods, and disposable absorbent articles comprising such surface-modified-clay linked water-absorbing polycarboxylate/polycarboxylic acid polymers.

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Номер записи: 5
05-07-2012 дата публикации

Antimicrobial raw material and method for manufacturing the same, and antimicrobial material

Номер: US20120171406A1
Автор: Hiroshi Mase, Koji Hirota
Принадлежит: Mitsui Chemicals Inc

Provided is an antimicrobial raw material having excellent antibacterial and corrosion-resistance properties, which can be directly formed as a film even on a plastic substrate with low heat-resistance or a substrate whereof the color or properties are likely to change due to heat, and this can be achieved at relatively low cost. The antimicrobial raw material is a laminated structure which comprises a substrate layer and a copper-tin alloy layer disposed on the substrate layer, and which has a thickness ranging from 5 nm to 200 nm. The substrate layer is made of resin, natural fiber, or paper, the resin having the deflection temperature under load being 115° C. or lower when measured in accordance with ASTM-D648-56 under a load of 1820 kPa. The copper-tin alloy layer contains over 60 at % but no more than 90 at % of copper and 10 at % or more but less than 40 at % of tin.

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Номер записи: 6
20-12-2012 дата публикации

Clay-based hemostatic agents and devices for the delivery thereof

Номер: US20120321691A1
Автор: Daniel J. Burns, Denny Lo, Francis X. Hursey, Giacomo Basadonna, Raymond J. Huey
Принадлежит: Z Medica LLC

A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

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Номер записи: 7
31-01-2013 дата публикации

Hemostatic sponge

Номер: US20130028975A1
Автор: Hans Christian Hedrich, Joris Hoefinghoff
Принадлежит: Baxter Healthcare SA, Baxter International Inc

The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that—said polymeric component is coated onto a surface of said matrix of a biomaterial, or—said matrix is impregnated with said polymeric material, or—both.

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Номер записи: 8
14-02-2013 дата публикации

Articles Comprising Reinforced Polyurethane Coating Agent

Номер: US20130040810A1
Автор: Axel Meyer, Jensen Kiziri Buhiru, Karl Haeberle, Klaus-Dieter HOERNER, Michaela Monika Czupik, Robin Lynn McKiernan
Принадлежит: Procter and Gamble Co

Articles, such as absorbent articles, are described, comprising a coating or film, for example applied to superabsorbent polymer particles, the coating or film containing a polyurethane polymer material, containing polyurethane polymers with covalently bonded modified silica-containing material.

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Номер записи: 9
14-02-2013 дата публикации

Devices and methods for the delivery of blood clotting materials to bleeding wounds

Номер: US20130041332A1
Автор: Jeffrey L. Horn, Raymond J. Huey
Принадлежит: Z Medica LLC

An apparatus for promoting the clotting of blood and controlling bleeding comprises a receptacle for retaining blood clotting material in particulate form therein. A pad for controlling bleeding comprises a mesh structure and a support attached to the mesh structure to facilitate the application of pressure to the pad and the wound. A bandage applicable to a bleeding wound comprises a mesh structure and a flexible substrate attached to the mesh structure, the substrate being a cloth or plastic member that may be adhesively attachable to cover a wound. In any embodiment, at least a portion of the receptacle or mesh structure is defined by a mesh having openings therein, and at least a portion of the particulate blood clotting material is in direct contact with blood. The mesh may include a zeolite powder impregnated or otherwise incorporated therein.

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Номер записи: 10
28-03-2013 дата публикации

Hemostatic sponge

Номер: US20130079695A1
Автор: Daniel J. Burns, Denny Lo, Francis X. Hursey, Giacomo Basadonna, Raymond J. Huey
Принадлежит: Z Medica LLC

A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

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Номер записи: 11
04-04-2013 дата публикации

System and method for treating leg ulcers

Номер: US20130085435A1
Автор: Khaled El-Tahlawy, Thomas S. Murphy
Принадлежит: Andover Healthcare Inc

In one aspect, a wound treatment system includes an inner layer comprising a foam material impregnated with a zinc oxide containing composition with or without calamine and/or ichthammol and in the presence or absence of antimicrobial agent (inorganic and/or organic). An optional outer layer comprises a short/long stretch compression bandage. In another aspect, a method of manufacturing the foam article impregnated with the zinc oxide containing composition is disclosed. In yet another aspect, a method of applying the wound treatment system to a patient's leg is disclosed. In still another aspect, a kit is provided including a foam layer impregnated with a zinc oxide containing composition; optionally, an elastic bandage component (e.g., long or short stretch elastic bandage); and, optionally, an outer stocking or sleeve, wherein the bandage system components are packaged together.

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Номер записи: 12
23-05-2013 дата публикации

Superabsorbent Comprising Pyrogenic Aluminum Oxide

Номер: US20130130895A1
Автор: Norbert Herfert, Thomas Daniel
Принадлежит: BASF SE

Superabsorbents comprising pyrogenic aluminum oxide exhibit a low caking tendency coupled with good absorption properties and rapid water absorption.

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Номер записи: 13
04-07-2013 дата публикации

Anti-microbial metal organic framework

Номер: US20130171228A1
Автор: Russell Edward Morris
Принадлежит: University of St Andrews

The present invention relates to metal organic framework materials which possess anti-microbial properties. The present invention also provides methods of preparing such metal organic framework materials and uses of the metal organic framework materials to prevent or treat microbial infections, or provide surfaces which limit contamination by micro-organisms.

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Номер записи: 14
08-08-2013 дата публикации

MEDICAL ADSORBENT AND METHOD FOR PRODUCING SAME

Номер: US20130202664A1
Автор: Hibi Keita, Kousaka Tsutomu, Kurokawa Hiroyuki, Suzuki Keisuke
Принадлежит:

A medical adsorbent for oral administration that has low dosage and excellent adsorptive capacity and selective adsorption for toxins to be removed, and is also economical and environmentally friendly. The medical adsorbent comprises granular activated carbon that is activated carbon obtained by carbonization and activation of refined cellulose or regenerated cellulose, and having a mean pore diameter of 1.5 to 2.2 nm, a BET specific surface area of 700 to 3000 m/g, a mean particle size of 100 to 1100 μm, a surface oxide content of 0.05 meq/g or greater and a packing density of 0.4 to 0.8 g/mL, and it can be used as a therapeutic or prophylactic agent for kidney disease or liver disease, for oral administration. 1. A medical adsorbent that comprises granular activated carbon that is activated carbon obtained by carbonization and activation of refined cellulose or regenerated cellulose , and that has a mean pore diameter of 1.5 to 2.2 nm , a BET specific surface area of 700 to 3000 m/g , a mean particle size of 100 to 1100 μm , a surface oxide content of 0.05 meq/g or greater , and a packing density of 0.4 to 0.8 g/mL.2. The medical adsorbent according to wherein the granular activated carbon is a therapeutic or prophylactic agent for kidney disease or liver disease claim 1 , for oral administration.3. A method for producing a medical adsorbent whereby in production of granular activated carbon according to claim 1 , refined cellulose or regenerated cellulose is carbonized at 300° C. to 700° C. under a nitrogen atmosphere claim 1 , and then subjected to steam-activation at 750° C. to 1000° C. claim 1 , acid cleaning and heat treatment at 500° C. to 800° C.4. A method for producing a medical adsorbent whereby in production of granular activated carbon according to claim 1 , refined cellulose or regenerated cellulose is impregnated into ammonium phosphate or a metal phosphate claim 1 , carbonized at 300° C. to 700° C. under a nitrogen atmosphere claim 1 , and then ...

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Номер записи: 15
05-09-2013 дата публикации

ANTIMICROBIAL ADHESIVE FORMULATION AND FILM DRESSINGS HAVING AN ANTIMICROBIAL ADHESIVE

Номер: US20130231599A1
Автор: Eddy Patrick E.
Принадлежит:

An adhesive formulation is provided for use in a film wound dressing. The adhesive formulation includes a medical-grade adhesive and an antimicrobial substance. This adhesive formulation may be coated onto one or more surfaces of a medical-grade transparent film suitable for a wound dressing. The antimicrobial material may be a silane quaternary ammonium salt. The silane quaternary ammonium salt may comprise 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride. The 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride may constitute about 72% of the silane quaternary ammonium salt. The medical-grade adhesive may comprise an acrylic adhesive. Further, the adhesive formulation may include about 0.01% to about 60% of the antimicrobial substance. The transparent film dressing may further include a release liner applied over the coated side(s) of the transparent film. The transparent film may comprise polyurethane. 1. A film dressing comprising:a film having a first side and a second side;an adhesive formulation coated on at least one of said sides of said film; anda release liner applied over said adhesive formulation,wherein said adhesive formulation comprises a mixture of a medical-grade adhesive and an antimicrobial substance,wherein said adhesive formulation includes about 0.01% to about 60% of said antimicrobial substance,wherein said antimicrobial substance is a silane quaternary ammonium salt comprising 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride, andwherein said medical-grade adhesive comprises an acrylic adhesive.2. The film dressing of claim 1 , wherein said film comprises polyurethane.3. The film dressing of claim 1 , wherein said film is transparent.4. The film dressing of claim 1 , wherein said film is opaque.5. The film dressing of claim 1 , wherein said 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride constitutes about 72% of said silane quaternary ammonium salt.6. A transparent film dressing comprising:a ...

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Номер записи: 16
19-09-2013 дата публикации

Wound and therapy compress and dressing

Номер: US20130245578A1
Автор: Aaron N. Ingram, Mark H. Bruder
Принадлежит: Bruder Healthcare Co

A method of providing moisture therapy to a subject by applying a moist therapy compress against a treated body portion. The moist therapy compress includes a fluid-permeable shell, a flexible backing fastened to the shell to define an enclosure, and a hydrophilic zeolite fill granules loosely contained within the enclosure. The therapy compress is exposed to a source of moisture to cause absorption of water into the a hydrophilic zeolite, and the moisture is delivered from the hydrophilic zeolite through the fluid permeable shell to the treated body portion.

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Номер записи: 17
03-10-2013 дата публикации

Particulate substances comprising ceramic particles for delivery of biomolecules

Номер: US20130259942A1
Автор: Christophe Jean Alexandre BARBÉ, Kim Suzanne Finnie, Samuel Knight, Toby Johnston Passioura
Принадлежит: Australian Nuclear Science and Technology Organization

A particulate substance comprising particles of a ceramic matrix bearing a functional group, the functional group being capable of promoting penetration of the particles into cells, and a biomolecule disposed within pores of the particles, the biomolecule being releasable from the particles by dissolution of the ceramic matrix.

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Номер записи: 18
07-11-2013 дата публикации

POLYURETHANE USEFUL FOR ORTHOPEDICS EXTERNAL FIXING SYSTEM IN COMPLEX ENVIRONMENT AND PREPARATION METHOD THEREOF

Номер: US20130296522A1
Автор: ZHU Xieping
Принадлежит:

A polyurethane used for orthopedics external fixing system in complex environment is obtained by reaction of mixture of polyether polyol with modified isocyanate in the weight ratio of 1:0.6-0.75. The modified isocyanate is obtained by reaction of polyphenyl polymethylene isocyanate with polyether diol. The components and corresponding weight percents of the mixture of polyether polyol are as follows: 60-65% polyether polyol as shown by formula (I), in the formula, m is an integer of 7-15, R represents mannitol, sucrose or pentaerythritol; 0.3-1% catalyst; 0.1-2% foam stabilizer; 0.1-2% or 3-20% foaming agent; 25-40% filler and 0.5-2% functional auxiliary agent. The method of producing the polyurethane is also provided. 2. The polyurethane of claim 1 , wherein the modified isocyanate is prepared by using a polyphenylpolymethylene isocyanate and the polyether glycol as raw materials.3. The polyurethane of claim 1 , wherein the catalyst in the polyether polyol mixture is selected from dimethyl ethylenimine claim 1 , dimethyl ethanolamine claim 1 , or triethylene diamine.4. The polyurethane of claim 1 , wherein the foam stabilizer in the polyether polyol mixture is a silicone stabilizer.5. The polyurethane of claim 1 , wherein the foaming agent in the polyether polyol mixture is water or CHCClF.6. The polyurethane of claim 5 , whereinif the foaming agent is water, the content of the foaming agent is 0.1-2 wt. % of the polyther polyol mixture; and{'sub': 3', '2, 'if the foaming agent is CHCClF, the content of the foaming agent is 3-20 wt. % of the polyther polyol mixture.'}7. The polyurethane of claim 1 , wherein the filler in the polyther polyol mixture is calcium carbonate claim 1 , or barium sulfate.8. The polyurethane of claim 1 , wherein the functional additive in the polyther polyol mixture is silica.9. A method for preparing the polyurethane of claim 1 , comprising the steps of:a) mixing the polyphenylpolymethylene isocyanate and the polyether glycol, and ...

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Номер записи: 19
07-11-2013 дата публикации

Gel sheet containing lipid peptide gelator and polymeric compound

Номер: US20130296761A1
Автор: Masahiro Goto, Nobuhide Miyachi, Takayuki Imoto, Takehisa Iwama, Tsubasa Kashino
Принадлежит: Kyushu University NUC, Nissan Chemical Corp

There is provided a gel sheet that has high biocompatibility and safety, can contain both a hydrophilic medicinal agent and a hydrophobic medicinal agent, and provides an excellent feel in use during the application onto human skin or others. A gel sheet including: a lipid peptide gelator including a low molecular weight lipid peptide having a molecular weight of 1,000 or less or a pharmaceutically usable salt of the lipid peptide; and a polymeric compound, wherein the polymeric compound is included in an amount of more than 1% (w/w) and less than 50% (w/w) with respect to the total mass of the gel sheet.

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Номер записи: 20
28-11-2013 дата публикации

Reduced-pressure dressings, systems, and methods employing desolidifying barrier layers

Номер: US20130317464A1
Автор: Christopher Brian Locke, Timothy Mark Robinson
Принадлежит: Kci Licensing Inc

Reduced-pressure medical dressings, systems, and methods involve a dressing with a first barrier layer that desolidifies when exposed to a fluid—typically a liquid—to form a treatment aperture in the first barrier that is used to deliver reduced pressure to a tissue site. The first barrier layer is formed from a desolidifying material. The system includes a drape covering a second surface of a manifold and a portion of the patient's epidermis to provide a substantially sealed space containing a manifold and the first barrier layer. Other systems, dressings, and methods are also disclosed.

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Номер записи: 21
05-12-2013 дата публикации

SPRAY FOAM SPLINT

Номер: US20130324897A1
Автор: Martin Kevin D.
Принадлежит: USA, as Represented by the Secretary of the Army

Orthopedic splinting materials and methods for stabilizing an injured limb or extremity of a human or animal comprising applying a foam to the limb or extremity and allowing the foam set to sufficient rigidity, which can be in less than 60 seconds. The foam, such as a Spray Polyurethane Foam, can be sprayed directly on the skin without producing an amount of heat release that is painful or uncomfortable on the skin. Also provided is a kit for stabilizing an injured limb or extremity comprising a dispenser comprising the present foam. Further provided is situ preparation and application of a compression bandage on an injured patient in an emergency or combat situation comprising applying the present foam. A spine board and a method for making the same comprising applying the present foam to the patient's back, then contacting the foam with a board or flat surface before the foam sets. 1. A cast for stabilizing an injured limb or extremity of a human or animal comprising a foam applied directly onto the skin of the limb or extremity and allowed to set.2. The cast according to claim 1 , wherein the foam applied directly on the skin does not produce an amount of heat release that is painful or uncomfortable on the skin of the human or animal.3. The cast according to claim 1 , wherein the foam is a polyurethane foam.4. The cast according to claim 1 , wherein the foam is a two-component quick-cure spray polyurethane foam.5. The cast according to claim 1 , wherein the foam is FROTH-PAK foam claim 1 , a two-component quick-cure polyurethane foam.6. The cast according to claim 1 , wherein the foam is a soy-based foam.7. The cast according to claim 1 , wherein the foam sets as an open-cell foam.8. The cast according to claim 1 , wherein the foam sets to sufficient rigidity in less than 60 seconds.9. A method for stabilizing an injured limb or extremity of a human or animal comprising:applying a foam on the injured limb or extremity of a human or animal, wherein the foam does ...

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Номер записи: 22
26-12-2013 дата публикации

HEMOSTATIC DEVICES

Номер: US20130344131A1
Автор: Dubey Dina, Lo Denny
Принадлежит:

Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon. 1. A hemostatic device comprising:a substrate;a hemostatic clay material disposed on at least one side of the substrate; anda binder configured to bind the hemostatic material to the substrate;wherein the hemostatic device is subjected to a drying process;wherein the binder has an effect of substantially retaining the hemostatic material on the substrate when exposed to blood; andwherein the device is configured such that when treating bleeding, application of the device is capable of causing blood to be absorbed into the substrate and causing at least a portion of the clay material to come into contact with blood to assist in accelerating clotting.2. The device of claim 1 , wherein the substrate comprises at least one of the following: a gauze material claim 1 , a woven material claim 1 , a sponge claim 1 , a sponge matrix claim 1 , or a foamed polymer.3. The device of claim 1 , further comprising a pharmaceutically-active composition selected from the group consisting of antibiotics claim 1 , antifungal agents claim 1 , antimicrobial agents claim 1 , anti-inflammatory agents claim 1 , analgesics claim 1 , antihistamines claim 1 , compounds containing silver or copper ions ...

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Номер записи: 23
16-01-2014 дата публикации

WOUND CARE COMPOSITIONS

Номер: US20140017320A1
Автор: Day Delbert E., Jung Steven B.
Принадлежит: The Curators of the University of Missouri

A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of PO, SiO, and BO; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound. 1. Glass-based particles of a biocompatible material intermixed into a carrier for wound-care management ,{'sub': 2', '5', '2', '2', '3, 'wherein the glass-based particles comprise a glass-former selected from the group consisting of PO, SiO, BO, and'}wherein the carrier is a biocompatible ointment or cream or a surgical glue for closing a wound.2. The glass-based particles intermixed into a carrier of claim 1 , wherein the glass-based particles comprise from about 40 to about 80 wt % BO.3. The glass-based particles intermixed into a carrier of claim 2 , wherein the glass-based particles comprise one or more alkali oxides selected from the group consisting of LiO claim 2 , NaO claim 2 , KO claim 2 , and RbO claim 2 , and one or more alkaline earth oxides selected from the group consisting of MgO claim 2 , SrO claim 2 , BaO claim 2 , and CaO.4. The glass-based particles intermixed into a carrier of claim 2 , wherein the glass-based particles comprise from about 50 to about 80 wt % BO.5. The glass-based particles intermixed into a carrier of claim 2 , wherein the glass-based particles comprise from about 5 to about 20 wt % of one or more alkali oxides selected from the group consisting of LiO claim 2 , NaO claim 2 , KO claim 2 , and RbO claim 2 , and from about 5 to about 40 wt % of one or more alkaline earth oxides selected from the group consisting of MgO ...

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Номер записи: 24
06-02-2014 дата публикации

FOAM CORE SANDWICH SPLINT

Номер: US20140039366A1
Автор: Joseph Mark
Принадлежит:

A multi-layered composite material suitable for use in orthopedics includes a foam core layer bonded between two layers of thermoformable polymer material. The thermoformable material is heat formable within a target temperature range allowing for rapid heating and application to a patient such as in the form of a splint. While within the target temperature range, the composite material includes a dwell time sufficiently long to enable proper fitment and adjustment, yet not overly long requiring extended periods of holding the composite material in place. The composite material is very light yet extremely rigid and easily conformable to patients. 1. A composite material , comprising:a first layer of thermoformable material;a second layer of thermoformable material; anda foam layer disposed between, and bonded to, the first and second layers of thermoformable material, wherein the first and second layers of thermoformable material are heat formable within a target temperature range and substantially rigid at temperatures below a minimum formable temperature of about 130 degrees Fahrenheit.2. The composite material of claim 1 , wherein the first and second layers of thermoformable material are heat formable within a target temperature range of about 160-240 degrees Fahrenheit.3. The composite material of claim 1 , wherein the first and second layers of thermoformable material are heat formable within a target temperature range of about 190-225 degrees Fahrenheit.4. The composite material of claim 1 , wherein the first and second layers of thermoformable material have a density which is about three to five times greater than a density of the foam layer.5. The composite material of claim 4 , wherein the density of the first and second layers of thermoformable material is about 1200 kg/m̂3 and the density of the foam layer is about 300 kg/m̂3.6. The composite material of claim 1 , wherein the first and second layers of thermoformable material each have a thickness which ...

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Номер записи: 25
20-02-2014 дата публикации

Sheet-like carbon nanotube-polymer composite material

Номер: US20140052037A1
Автор: Bogdan Bogdanov, Steven Cuypers
Принадлежит: Orfit Industries NV

Use of a sheet-like composite material for the manufacture of an immobilization element, wherein the sheet-like composite material is made from a material comprising a thermoplastic polymer containing carbon nanotubes as a fibrous reinforcing material, obtainable by dispersing carbon nanotubes in a dispersing liquid in which the thermoplastic polymer does not dissolve, subjecting the dispersion to an ultrasonic treatment, adding of particles thermoplastic polymer to the dispersion and mixing of the thermoplastic polymer with the dispersion of carbon nanotubes, removing of the dispersing liquid, forming of the thermoplastic polymer impregnated with carbon nanotubes into a sheet.

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Номер записи: 26
27-02-2014 дата публикации

SEMI-RIGID SHOULDER BRACES AND RELATED METHODS

Номер: US20140058304A1
Автор: Csernica Riley Morgan, Donaldson Meredith Cole, Ex-Lubeskie Chelsea Lea, Grove Kaitlin Kathleen, Thigpen Charles Alden
Принадлежит:

Shoulder braces for inhibiting secondary anterior shoulder dislocations that are configured to allow for a wide range of motion for mobility and stabilization, include a brace body with a single arm portion configured to reside about a shoulder of a user and a torso portion, a plurality of shoulder straps extending over the single arm portion shoulder, a substantially rigid thermoplastic insert releasably held by the arm portion of the brace body. The insert can have a user-specific custom shape that substantially conforms to shoulder anatomy of the shoulder of the user. The brace can also include at least one adjustable length laterally extending torso strap attached to the torso portion. 1. A shoulder brace , comprising:a brace body with an arm portion configured to reside about a shoulder of a user and a torso portion;a plurality of shoulder straps extending over the arm portion from a front upper portion to a back upper portion of the brace body; anda substantially rigid thermoplastic insert releasably held by the arm portion of the brace body, wherein the insert has a user specific custom shape that substantially conforms to a shoulder of the user.2. The shoulder brace of claim 1 , wherein the brace body comprises an expandable breathable compressive fabric.3. The shoulder brace of claim 1 , wherein the at least one torso strap is a single strap that has an adjustable length and resides on only one side portion of the brace body claim 1 , and wherein an opposing side portion includes two long edge portions that are releasably attachable together.4. The shoulder brace of claim 1 , wherein the plurality of straps comprise a plurality of closely spaced straps that extend from a front upper portion of the brace body to a rear upper portion of the brace body and that are sized and configured to provide stabilization of glenohumeral ligaments claim 1 , and wherein the straps have adjustable lengths.5. The shoulder brace of claim 1 , wherein the brace body arm portion ...

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Номер записи: 27
27-03-2014 дата публикации

Adhesive composition for soft tissues, adhesive composition for wound dressing or wound dressing composition

Номер: US20140086967A1
Автор: Hiroshi Naruse, Noriaki Asada
Принадлежит: Mitsui Chemicals Inc

The present invention provides an adhesive composition for soft tissues, an adhesive composition for wound dressing or a wound dressing composition, not only having low toxicity, low harmfulness and high adhesive strength but also being excellent in workability during application and being capable of forming films of excellent properties. The compound of the present invention is comprised a monomer (A), polymer particles (B) having a specific weight-average molecular weight and a specific volume mean particle diameter, and a polymerization initiator composition (C) containing an organoboron compound is produced.

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Номер записи: 28
10-04-2014 дата публикации

COMPOSITES CONTAINING POLYPEPTIDES ATTACHED TO POLYSACCHARIDES AND MOLECULES

Номер: US20140099444A1
Автор: Catchmark Jeffrey M., Mears Dana Meredith, Mishra Niharika, Siggins John
Принадлежит: THE PENN STATE RESEARCH FOUNDATION

This document provides methods and materials related to composites or coatings containing polypeptides attached to polysaccharides and/or molecules. For example, methods and materials related to composites or coatings containing polypeptides (e.g., casein polypeptides) attached to polysaccharides (e.g., cellulose) and/or molecules (e.g., calcium containing molecules such as calcium phosphate and calcium carbonate and/or polyesters such as polylactic acid and polyhydroxybutyrate) are provided. A coating provided herein can include both cationic and ionic polymers, polypeptides, or polysaccharides. 120-. (canceled)21. A method for coating a product , wherein said method comprises:(a) combining casein, a calcium containing mineral, and a biopolymer to form a mixture, and(b) applying said mixture to a product to form a coated product.22. The method of claim 21 , wherein said calcium containing mineral is calcium carbonate.23. The method of claim 21 , wherein said calcium containing mineral is calcium phosphate.24. The method of claim 21 , wherein said biopolymer comprises polylactic acid.25. The method of claim 21 , wherein said biopolymer comprises poly(lactic-co-glycolic) acid.26. The method of claim 21 , wherein said step (a) comprises mixing said casein and said calcium containing mineral in water.27. The method of claim 21 , wherein said step (a) comprises mixing said casein and said calcium containing mineral in water having a pH of 7-11.28. The method of claim 21 , wherein said step (a) comprises mixing said casein and said calcium containing mineral in solution claim 21 , wherein the solid content of said solution is from 0.5 percent to 5 percent.29. The method of claim 21 , wherein said step (a) comprises (i) mixing said casein and said calcium containing mineral in solution and (ii) adding said biopolymer to said solution.30. The method of claim 21 , wherein said mixture is applied to said product using a gravure coating process.31. The method of claim 21 , ...

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Номер записи: 29
06-01-2022 дата публикации

SYNTHETIC ANTIMICROBIAL MINERAL COMPOSITIONS, METHODS OF MAKING AND USING SAME

Номер: US20220000912A1
Автор: Loots Gabriela G., Martin Kelly Anne, Morrison Keith David, Samo Ty James
Принадлежит:

Provided herein are pharmaceutical compositions comprising a Fe-exchanged fluorinated synthetic smectite and a synthetic semiconducting metal sulfide. The compositions can be used to treat topical conditions and gastrointestinal ailments, and can be incorporated into wound dressings, hydrogels, personal protective equipment, and 3D printed articles. Also provided are methods of synthesizing the Fe-exchanged fluorinated synthetic smectite and methods of making the synthetic semiconducting metal sulfide. 1. A pharmaceutical composition comprising Fe-exchanged fluorinated synthetic smectite and synthetic semiconducting metal sulfide.2. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite is present in an amount of 80 wt % to 98.5 wt % claim 1 , based on the total weight of the composition and wherein the synthetic semiconductinq metal sulfide is present in an amount of 1.5 wt % to 20 wt % based on the total weight of the composition.3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite claim 1 , at an octahedral site claim 1 , comprises Li.11. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite claim 1 , at an octahedral site claim 1 , comprises Mg claim 1 , Cu claim 1 , Zn claim 1 , or Fe.12. (canceled)13. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite comprises from 5 meq to 100 meq of ferrous iron (Fe) claim 1 , per 100 g of the Fe-exchanged fluorinated synthetic smectite.14. (canceled)15. (canceled)16. The composition of claim 1 , free of arsenic claim 1 , lead claim 1 , cobalt claim 1 , nickel claim 1 , mercury claim 1 , or uranium.17. The composition of claim 1 , wherein the semiconducting metal sulfide comprises one or more of synthetic pyrite claim 1 , synthetic acanthite claim 1 , synthetic chalcocite claim 1 , synthetic bornite claim ...

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Номер записи: 30
03-01-2019 дата публикации

ABSORBENT SHEET

Номер: US20190000676A1
Автор: KAWAGUCHI Asami, SAITO Yuko, SHIRAI Ayako, SUGAYA Mariko, YAEZAWA Takashi
Принадлежит:

The purpose of the present invention is to provide an absorbent sheet capable of sufficiently absorbing exudates exuding from an area of a lesion and exhibiting a powerful deodorizing effect for illness-associated odors. The invention relates to an absorbent sheet with deodorizing functions having an absorbent region and a deodorizing region situated to at least one side of the absorbent region, wherein the absorbent region contains cellulosic fibers, an absorbent polymer and a thermal adhesive resin, and the deodorizing region contains cellulosic fibers, a deodorizing agent and a thermal adhesive resin. 1. An absorbent sheet with deodorizing functions having an absorbent region and a deodorizing region situated to at least one side of the absorbent region , wherein:the absorbent region contains cellulosic fibers, an absorbent polymer and a thermal adhesive resin, andthe deodorizing region contains cellulosic fibers, a deodorizing agent and a thermal adhesive resin.2. The absorbent sheet with deodorizing functions according to claim 1 , wherein the absorbent polymer is absorbent fibers.3. The absorbent sheet with deodorizing functions according to claim 1 , wherein the content of the absorbent polymer is 10 to 50% by mass relative to the total mass of the solid content constituting the absorbent region.4. The absorbent sheet with deodorizing functions according to claim 1 , wherein the absorbent polymer contains a sodium polyacrylate resin.5. The absorbent sheet with deodorizing functions according to claim 1 , wherein the deodorizing agent contains a component that reacts with at least one selected from sulfides claim 1 , sulfurs and amines.6. The absorbent sheet with deodorizing functions according to claim 1 , wherein the deodorizing agent contains a polyphenol and a polyphenol oxidase.7. The absorbent sheet with deodorizing functions according to claim 1 , wherein the deodorizing agent contains at least one selected from metals claim 1 , minerals claim 1 , ...

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Номер записи: 31
02-01-2020 дата публикации

Compositions and methods to promote wound healing

Номер: US20200000711A1
Автор: Fu-shin X. YU
Принадлежит: WAYNE STATE UNIVERSITY

The present disclosure describes compositions and methods to promote wound healing. The compositions and methods include an interleukin-1 beta (IL-1β) receptor antagonist (IL-1Ra), such as anakinra. The IL-1Ra can be administered topically to a chronic wound including a diabetic ulcer.

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Номер записи: 32
05-01-2017 дата публикации

DRUG DELIVERY COMPOSITIONS AND METHODS

Номер: US20170000824A1
Автор: RAZAVI Ali
Принадлежит:

A drug delivery composition is disclosed which includes a triple salt proxy functional group and at least one amino acid functional group. A method of forming the drug delivery composition includes reacting a triple salt with at least one amino acid in an aqueous environment. A biodegradable fabric is disclosed which includes a polymerized structure of a triple salt proxy functional group and at least one amino acid functional group. 1. A drug delivery composition comprising a triple salt proxy functional group and at least one amino acid functional group , wherein the triple salt proxy functional group includes a peroxy moiety.2. The drug delivery composition of claim 1 , wherein the triple salt proxy functional group is KHSO.3. The drug delivery composition of claim 1 , wherein the amino acid functional group is selected from the group consisting of derivatives of glutamine claim 1 , alanine claim 1 , aspartic acid claim 1 , lysine claim 1 , glycine claim 1 , cysteine claim 1 , arginine claim 1 , proline claim 1 , naturally occurring peptides claim 1 , artificially occurring peptides claim 1 , and combinations thereof.4. The drug delivery composition of claim 1 , wherein the triple salt proxy functional group includes the property of broad spectrum antimicrobial activities against bacteria claim 1 , fungi and viruses.5. The drug delivery composition of claim 1 , wherein the drug delivery composition further comprises a plurality of amino acid functional groups.6. The drug delivery composition of claim 5 , wherein the plurality of amino acid functional groups further comprises amino acid health benefits.7. The drug delivery composition of claim 1 , wherein the drug delivery composition is a powder base material.8. The drug delivery composition of claim 7 , wherein the powder base material further comprises the property of rapid solubility in an aqueous solution.9. A method for forming a drug delivery composition comprising reacting a triple salt including a peroxy ...

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Номер записи: 33
04-01-2018 дата публикации

SYSTEMS AND METHODS FOR INCONTINENCE CONTROL

Номер: US20180000981A1
Автор: Berryman Thomas J., Taylor John M.
Принадлежит:

A system for managing female incontinence includes a body of biocompatible material configured to fit between the labia minora and the vestibule floor, the body having a surface configured to occlude the urethral meatus, an adhesive carried on at least a first portion of the surface and configured to provide a sealing engagement between the body and the urethral meatus, and a substance carried by at least one of the body and the adhesive and configured for controlling the odor of the general vaginal-urethral area of a female. 1a body of biocompatible material configured to fit between the labia minora and the vestibule floor, the body having a surface configured to occlude the urethral meatus;an adhesive carried on at least a first portion of the surface and configured to provide a sealing engagement between the body and the urethral meatus; anda substance carried by at least one of the body and the adhesive and configured for controlling the odor of the general vaginal-urethral area of a female.. A system for managing female incontinence comprising: This application is a continuation of U.S. patent application Ser. No. 15/206,157, filed on Jul. 8, 2016, which is a continuation of U.S. patent application Ser. No. 14/870,104, filed on Sep. 30, 2015, which claims the benefit of priority to U.S. Provisional App. No. 62/059,833, filed on Oct. 3, 2014, all of which are incorporated by reference in their entirety herein for all purposes. Priority is claimed pursuant to 35 U.S.C. §120 and 35 U.S.C. §119.The field of the invention generally relates to devices for treating urinary incontinence.Urinary incontinence is a troublesome problem for many individuals. Urinary stress incontinence is a particular form of urinary incontinence wherein a physical occurrence may cause unwanted leakage of urine. For example, a sudden spike in abdominal pressure from sneezing, coughing or exercise may exceed the resistive pressure of the urethra for a brief moment, causing an involuntary ...

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Номер записи: 34
04-01-2018 дата публикации

COMPOSITION AND DRESSING WITH NITRIC OXIDE

Номер: US20180000985A1
Автор: Araya Abraham, Broderick Sonya Theresa, Minihan Alan Reginald, Robbins Paul Matthew, Waring Michael J.
Принадлежит:

A dressing composition for use as a skin dressing comprises an elastomeric-adhesive composition, and a zeolite comprising releasably adsorbed nitric oxide. The zeolite may comprise a transition metal cation such as Co, Fe, Mn, Ni, Cu, Zn, Ag or a mixture thereof as an extra-framework metal cation, preferably Zn. The elastomeric adhesive composition may be a hydro-colloid-adhesive composition comprising, hydrocolloid and elastomer. The dressing composition releases nitric oxide, which may have beneficial effects, when used on wounds or moist skin, with a substantially constant release rate over a long period of time. A dressing including a layer of the dressing composition has a backing layer and may have a release liner removably attached to the skin-contacting surface of the dressing layer. 117-. (canceled)18. A nitric oxide-releasing dressing composition for use as a skin dressing comprising:i) an elastomeric-adhesive composition comprising an elastomeric polymer in combination with one or more water-soluble or water-swellable hydrocolloids; 'natural or synthetic rubber or mixtures thereof, block copolymers of styrene/butadiene, polybutenes and polyacrylates; and', 'wherein the elastomeric polymer is selected from the group consisting of 'polyhydroxyalkyl acrylates and methacrylates, polyvinyl lactams, polyvinyl alcohols, polyoxyalkylenes, polyacrylamides, polyacrylic acid, polystyrene sulfonates, natural or synthetically modified polysaccharides, alginates, gelatine, xanthan gums, guar gums, and cellulosic polymers;', 'the one or more water-soluble or water-swellable hydrocolloids are selected from the group consisting ofii) a zeolite dispersed within the elastomeric-adhesive composition, said zeolite comprising releasably adsorbed nitric oxide.19. A dressing composition according to comprising based on the weight of the dressing composition from 99.5 to 30% by weight of the elastomeric-adhesive composition claim 18 , and from 0.5 to 70% by weight of zeolite.20. ...

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Номер записи: 35
02-01-2020 дата публикации

MULTI-FUNCTION DRESSING STRUCTURE FOR NEGATIVE-PRESSURE THERAPY

Номер: US20200000955A1
Автор: Andrews Brian, Locke Christopher Brian, Robinson Timothy Mark, Whyte David George
Принадлежит:

Systems, methods, and apparatuses for forming a multi-function core for a dressing are described. The multi-function core includes a contact layer configured to be positioned adjacent to a tissue site, a wicking layer adjacent to the contact layer, an ion exchange layer adjacent to the wicking layer, an absorbing layer adjacent to the ion exchange layer, a blocking layer adjacent to the absorbing layer, and an odor-absorbing layer adjacent to the blocking layer. The contact layer, the wicking layer, the ion exchange layer, the absorbing layer, the blocking layer, and the odor-absorbing layer are coextensive and formed from a plurality of fibers disposed in a fibrous web. Methods of manufacturing the multi-function core are also described. 170-. (canceled)71. A method for providing negative-pressure therapy to a tissue site , the method comprising: placing a sealing member over the tissue interface and sealing the sealing member to tissue surrounding the tissue site to form a sealed space;', 'fluidly coupling a negative-pressure source to the sealed space;', a contact layer configured to be positioned adjacent to the tissue interface;', 'a fluid dispersion layer coupled to the contact layer;', 'an ion exchange layer coupled to the fluid dispersion layer;', 'a liquid retention layer coupled to the ion exchange layer;', 'a liquid blocking layer coupled to the liquid retention layer;', 'an odor removal layer coupled to the liquid blocking layer; and, 'positioning a fluid management apparatus between the tissue interface and the sealing member, the fluid management apparatus comprising, 'operating the negative-pressure source to draw fluid from the sealed space through the fluid management apparatus and generate a negative pressure in the sealed space., 'positioning a tissue interface adjacent to the tissue site;'}72. The method of claim 71 , wherein the fluid dispersion layer claim 71 , the ion exchange layer claim 71 , the liquid retention layer claim 71 , the liquid ...

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Номер записи: 36
02-01-2020 дата публикации

Solid dressing for treating wounded tissue and processes for mixing fibrinogen and thrombin while preserving fibrin-forming ability, compositions produced by these processes, and the use thereof

Номер: US20200000957A1
Автор: Angela Mitchel, Belinda Wilmer, Christine Haefling, Daniel Graham, Dawson Beall, Jerry Kanellos, Martin Macphee, PETER Brown, Rich Degeronimo, Rob Martel, Shirley Miekka
Принадлежит: Resource Transition Consultants LLC

Fibrin Sealant products are used for topical hemostasis and tissue adherence. They are composed of two main reagents, fibrinogen and thrombin. When mixed in solution fibrinogen is converted to fibrin upon the addition of activated thrombin. Therefore typically these two components are stored separately in a lyophilized or liquid state, and mixed, upon or immediately before, application to a patient. While effective, these products require significant preparation that must take place immediately before application, thus delaying treatment and limiting the use of these haemostatic products to the treatment of mild forms of low pressure and low volume bleeding. Attempts to eliminate this delay and expand the usefulness and effectiveness of these products have resulted in products produced by processes that require the separation of these components and their deposition in distinct layers within the product. The processes described herein permit the mixing of fibrinogen and thrombin during product manufacture, without excessive fibrin formation. The resulting ‘pre-mixed’ fibrin sealant material can then be stored in either a frozen or dried state, or suspended in a non-aqueous environment. Activation of the material to form therapeutic fibrin sealant is accomplished by permitting the product to thaw (if frozen) or by the addition of water or other aqueous fluid, including blood, or other bodily fluids, if dried or suspended in a non-aqueous environment. The resulting material can be used to make a product in which a pre-mixed form of activatable fibrin sealant is a desired component.

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Номер записи: 37
03-01-2019 дата публикации

BANDAGE

Номер: US20190001016A1
Автор: Langen Guenter
Принадлежит:

The invention relates to a bandage comprising a flat web material as a substrate, wherein a self-adhesive cohesive adhesive compound is at least partially applied to both flat sides of the substrate, and the substrate is impregnated with a liquid preparation, characterised in that said adhesive compound comprises an anhydrous cohesive pressure sensitive adhesive which contains natural and/or synthetic rubber, this natural and/or synthetic rubber being dissolved in an organic solvent for application, or the pressure sensitive adhesive being molten for application. 1. A bandage comprising a flat-web material as substrate , wherein a self-adhesive cohesive adhesive has been at least partially applied on both flat sides of the substrate and the substrate has been impregnated with a liquid preparation , and wherein the self-adhesive cohesive adhesive comprises either an anhydrous cohesive pressure-sensitive adhesive comprising natural rubber and/or synthetic rubber , in which the natural rubber and/or synthetic rubber has been dissolved in an organic solvent for the purposes of application or an anhydrous cohesive pressure-sensitive adhesive which is a melted liquid for the purposes of application.2. The bandage of claim 1 , wherein the anhydrous cohesive pressure-sensitive adhesive which is a melted liquid for the purposes of application comprises natural rubber and/or synthetic rubber.3. The bandage of claim 1 , wherein the bandage is elastic in the longitudinal direction and/or transverse direction.4. The bandage of claim 1 , wherein the liquid preparation is selected from the group consisting of a single-phase solution claim 1 , a multiphase emulsion claim 1 , a gel and a foam.5. The bandage of claim 4 , wherein the liquid preparation is a single-phase solution based on a multiphase emulsion based on water with an addition of an inorganic substance claim 4 , or an organic substance.6. The bandage of claim 1 , wherein the substrate is selected from the group ...

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Номер записи: 38
04-01-2018 дата публикации

IMMOBILISATION ELEMENT AND ADDITIVE MANUFACTURING METHOD FOR MAKING SAME

Номер: US20180001547A1
Автор: Bogdanov Bogdan, Cuypers Steven, DE GRUYTERE Simon
Принадлежит: Orfit Industries N.V.

This invention relates to a method for manufacturing an individualized immobilization element for the non-invasive immobilization and/or mobilization of at least a segment of a body part of a patient in a predetermined position relative to a reference and/or in a pre-certain configuration. The method comprises the steps of (i) providing a data set that comprises a three-dimensional image of an outer contour of at least a part of the segment of the body part to be immobilized and/or mobilized and (ii) the manufacture of at least a part of the immobilization element by rapid manufacturing of a shape on the basis of said data set using a polymeric material containing a thermoplastic polymer having a melting point less than or equal to 100° C., wherein the polymer material contains a nucleating agent for enhancing the of the crystallization of the thermoplastic polymer. 1. A method for manufacturing an individualized immobilization element for the non-invasive immobilization and/or mobilization of at least a segment of a body part of a patient at a predetermined position relative to a reference and/or in a predetermined configuration , the method comprising:providing a data set that comprises a three-dimensional image of an outer contour of at least a portion of the segment of the body part to be immobilized and/or mobilized; andmanufacturing of at least a part of the immobilization element by rapid manufacturing of a shape based on said data set, using a polymeric material containing a thermoplastic polymer having a melting point less than or equal to 100° C.,wherein the polymeric material contains a nucleating agent capable of enhancing crystallization of the thermoplastic polymer, andwherein at least a portion of an inner surface of the shape has an inner contour which is complementary to the outer contour of the segment of the body part to be immobilized and/or mobilized.2. The method according to claim 1 , wherein the thermoplastic polymer is selected from the ...

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Номер записи: 39
05-01-2017 дата публикации

COMPOSITION AND PROCEDURE FOR OBTAINING A FILM OF MICRO POROUS THERMOPLASTIC POLYMER THAT IS ESPECIALLY SUITED TO THE PRODUCTION OF PERSONAL HYGIENE ARTICLES SUCH AS DIAPERS AND SANITARY TOWELS

Номер: US20170002157A1
Автор: Campos Beceiro Alberto
Принадлежит:

The present invention consists in a method and a composition for obtaining films of a thermoplastic polymer, preferably polyethylene, that are non-breathable and heavily charged with treated mineral particles in order to leave hollow spaces in the structure thereof, resulting in a significant reduction in density. 1. A method to obtain a non-breathable film having a micro-porous structure comprising a base polymer loaded with mineral particles covered by a fatty acid partially adhered to the base polymer by means of a co-polymer adhesive , the method comprising:a stage of dispersion of the particles of mineral load with the polymer; anda film forming stage.2. The method according to claim 1 , wherein the stage of dispersion of the polymer with the mineral load is carried out apart from the extrusion line of the film by mixers with arms claim 1 , turbo-mixers for powder or single or multiple screw extruders-mixers claim 1 , preferably double screw co-rotating extruders with gas removal assisted by a vacuum pump.3. The method according to claim 1 , wherein the stage of dispersion of the polymer with the mineral load is carried out directly in the film extrusion line claim 1 , through a simple or double screw extruder-mixer claim 1 , preferably a double screw co-rotating extruder with gas removal assisted by a vacuum pump.411. The method according to claim claim 1 , wherein claim 1 , in the film forming stage claim 1 , the film is only subject to hot stretching between the extrusion nozzle and the solidification of the film between 20/1 and 60/1 and no subsequent stretching. On the market there are two different types of outer covering for disposable diapers and sanitary towels, the first type consists of a matt polyethylene film, 18-22 microns thick, the second is obtained by lamination or co-extrusion of a 10-22 micron thick polyethylene film with an unwoven polypropylene fabric to give it a more textile appearance.Both Types may be breathable or non-breathable. ...

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Номер записи: 40
01-01-2015 дата публикации

ANTIMICROBIAL DEVICES COMPRISING HYPER-CONDUCTIVE AND DIELECTRIC LAYERS

Номер: US20150004361A1
Автор: Culpepper Taylor C.
Принадлежит:

Antimicrobial devices such as molded components can include surfaces which have a microbial field disruptive hyper-conductive layer covered by a dielectric surface layer, to continuously disinfect said surfaces. Also, the present invention relates to generally antimicrobial dressings and more particularly to dermal dressings and bandages providing antiseptic disinfection, comprising typical modern dressings and bandages stratified in close proximity to microbial field disruptive hyper-conductive elements or alloys which deactivate microbes by disrupting the electric field generated by and used by the microbes, and isolated the wound or surgical site tissue from said conductors with a layer or layers of dielectric film. 1. An antimicrobial device comprising:a hyper-conductive layer; anda dielectric layer adjacent to the hyper-conductive layer, wherein the antimicrobial device, has sufficient antimicrobial efficacy by a microbial field disruption effect.2. The antimicrobial device according to comprising an antimicrobial epidermal product or wound care product.3. A molded component comprising:a dielectric material having a non-planar surface, anda hyper-conductive layer adjacent to the dielectric material.4. The antimicrobial device according to claim 1 , wherein the dielectric layer is in direct contact with the hyper-conductive layer.5. The antimicrobial device according to claim 1 , wherein the hyper-conductive layer includes a metal.6. The antimicrobial device according to claim 5 , wherein the metal includes copper claim 5 , silver claim 5 , gold claim 5 , aluminum claim 5 , beryllium claim 5 , or any alloys containing copper claim 5 , silver claim 5 , gold claim 5 , aluminum claim 5 , beryllium.7. The antimicrobial device according to claim 1 , wherein the hyper-conductive layer is in a form of a solid foil claim 1 , a perforated foil claim 1 , film claim 1 , a woven mesh claim 1 , a non-woven mesh claim 1 , or a grid.8. (canceled)9. The antimicrobial device ...

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Номер записи: 41
01-01-2015 дата публикации

COPPER METAL ALLOY

Номер: US20150004429A1
Автор: AMENDUNI GRESELE Massimo, Penna Rodolfo
Принадлежит: MEDIKA S.r.l.

A copper metal alloy, for use in making elements for promoting and/or stimulating vital energy comprises between 60% and 70% in weight of copper (Cu), between 16% and 24% in weight of silver (Ag), between 3% and 6% in weight of zinc (Zn), between 3% and 6% in weight of manganese (Mn) and between 0.5%> and 6%> in weight of germanium (Ge). Tin (Sn) in percentage comprised between 3% and 6% can also be provided for. Platinum (Pt) can also be provided for between 0.1% and 5% in weight. The alloy is used for making for example sheets in form of plates or strips which are associated to articles of various types. 1. Copper metal alloy , useable in particular for making elements for promoting and/or stimulating vital energy in organisms , in particular in human beings , animals and plants , said alloy comprising:between 60% and 70% in weight of copper (Cu),between 16% and 24% in weight of silver (Ag),between 3% and 6% in weight of zinc (Zn),between 3% and 6% in weight of manganese (Mn),between 0.5% and 6% in weight of germanium (Ge).2. Alloy according to claim 2 , further comprising between 3% and 6% in weight of tin (Sn).3. Alloy according to claim 1 , characterised in that it is without tin (Sn).4. Alloy according to claim 2 , characterised in that said alloy further comprises between 0.1% and 5% in weight of platinum (Pt).5. Metal sheet claim 1 , for example in form of a plate or strip claim 1 , for use as an element for promoting and/or stimulating vital energy in living organisms claim 1 , in particular in human beings claim 1 , animals and plants claim 1 , characterised in that it is constituted by a copper metal alloy according to .6. Sheet according to claim 5 , characterised in that it has a thickness comprised between 0.1 mm and 1 mm claim 5 , preferably equivalent to 0.50 mm.7. Sheet according to claim 5 , characterised in that it is rectangular-shaped with rounded vertices and sides each having length comprised between 8 mm and 30 mm claim 5 , preferably ...

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Номер записи: 42
12-01-2017 дата публикации

Traumatic Wound Dressing System with Wrap

Номер: US20170007460A1
Автор: Bagwell Alison Salyer, Branham Kelly Dean, Cuevas Brian Joseph, Koenig David William, Kute Stephanie, Lalgudi Ramanathan S., MacDonald John Gavin, MCNAMARA David James, Schorr Phillip Andrew, Sweeney Andrew V.
Принадлежит:

A wound dressing system comprising a wrap and a frangible ampoule is provided. The wrap is configured to contact/surround a wound site and includes an oxygen catalyst. The ampoule includes an oxygen precursor. The catalyst and precursor are configured to form oxygen when combined. A wound dressing system including a container is also provided that includes a powder, wrap, and frangible ampoule. The powder is disposed within the container, which is configured to allow the powder to be dispersed onto a wound site when activated. The wrap, which may include an oxygen catalyst, is also disposed in the container and is configured to contact/surround the wound site. The ampoule, also disposed in the container, includes a liquid containing an oxygen precursor. The liquid is configured to contact the wrap when the container is activated. Further, the catalyst and precursor are configured to form oxygen when combined. 1. A wound dressing system comprising:a wrap configured to contact or surround a wound site;an oxygen catalyst; anda frangible ampoule including an oxygen precursor, wherein the oxygen catalyst and the oxygen precursor are configured to form oxygen when combined.2. The system of claim 1 , wherein the wrap includes an inner absorbent layer claim 1 , wherein the inner absorbent layer is positioned adjacent the wound site when the wrap is applied to the wound site.3. The system of claim 1 , wherein the wrap includes an outer protective layer.4. The system of claim 1 , wherein the wrap includes an elastic layer claim 1 , a breathable barrier layer claim 1 , or a combination thereof.5. The system of claim 1 , wherein an end of the wrap includes an adhesive.6. The system of claim 1 , wherein the wrap is a nonwoven composite.7. The system of claim 1 , wherein the wrap includes the oxygen catalyst.8. The system of claim 1 , wherein the oxygen precursor includes a peroxide.9. The system of claim 8 , wherein the peroxide includes hydrogen peroxide claim 8 , mannitol ...

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Номер записи: 43
11-01-2018 дата публикации

BIORESORBABLE WOUND DRESSING

Номер: US20180008743A1
Автор: Grafahrend Dirk, Neumüller Daniel, Plöger Frank, Reibel Denis
Принадлежит:

The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics. 1. A non-woven fabric comprising:fibres of a fibre raw material comprising bioresorbable and/or biocompatible polymers, the fibres including at least one biologically active substance, which is distributed in the fibres, wherein the biologically active substance is a GDF-5-related protein.2. The non-woven fabric of claim 1 , wherein the biologically active protein is additionally distributed on the fibres.3. The non-woven fabric of claim 1 , wherein the GDF-5-related protein comprises a cystine-knot-domain with an amino acid identity of at least 60% to the 102 aa-cystine-knot-domain of human GDF-5 according to amino acids 400-501 of SEQ ID NO:2.4. The non-woven fabric of claim 3 , wherein the GDF-5-related protein comprises a cystine-knot-domain with an amino acid identity of at least 70% claim 3 , 80% claim 3 , 90% or 95% to the 102 aa cystine-knot-domain of human GDF-5.5. The non-woven fabric of claim 1 , wherein the fibre raw material is selected from the group consisting of natural polymers claim 1 , synthetic polymers claim 1 , and polymers derived from fossile raw materials claim 1 , each of which may be modified or unmodified claim 1 , and combinations thereof.6. The non-woven fabric of claim 5 , wherein the natural polymers are selected from the group consisting of polypeptides such as collagen claim 5 , gelatin claim 5 , fibrin claim 5 , and casein claim 5 , polysaccharides such as dextran claim 5 , cellulose claim 5 , starch claim 5 , chitin claim 5 , chitosan claim 5 , alginate and hyaluronic acid claim 5 , polynucleotides claim 5 , and synthetic polymers such as polylactide (PLA) claim 5 , polyglycolide (PGA) ...

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Номер записи: 44
14-01-2016 дата публикации

Article comprising a polymeric substrate and a layer of silicone polymer

Номер: US20160009883A1
Автор: Jean-Marc Pernot
Принадлежит: Laboratoires Urgo SAS

The invention relates to an article comprising at least one polymeric substrate assembled on at least one layer of silicone polymer, characterized in that at least one of the polymeric substrate or of the layer of silicone polymer has been brought into contact with particles of titanium dioxide, magnesium oxide and/or zinc oxide, before assembly of said article, and in that at least one of the polymeric substrate or of the layer of silicone polymer has been brought into contact with water before or after assembly of said article. The invention also relates to a method of preparing said article, as well as the use of particles of titanium dioxide, magnesium oxide and/or zinc oxide, for improving the adherence between a polymeric substrate and a layer of silicone polymer.

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Номер записи: 45
09-01-2020 дата публикации

Devices and Methods for Protecting and Offloading Pressure in Casting Neuropathic and Diabetic Wounds of the Foot

Номер: US20200009287A1
Автор: Anderson Danny E., Anderson Kimberly G.
Принадлежит: WoundKair Concepts, Inc.

A method and device are shown for use in casting for Total Contact Casting for offloading pressure in neuropathic and diabetic wounds or fractures of the appendages such as the human leg or foot. The outer casting material used can be comprised of traditional casting materials. A total foot protection pad underlies the traditional casting materials. It is a one piece moldable system that encompasses the total foot from the Achilles along the lateral and medial foot, covering the plantar surface, the malleoli and folds and extends over the dorsum. The one piece system has adhesive backing on a contact side to facilitate its application and/or forms a total foot protection pad beneath the outer hardened casting material. 1. An article suitable for use in forming a total contact cast around the foot and leg of a human patient , the article comprising:a unitary blank having a top contact surface and an opposite bottom surface and having major and minor generally rectangular planar regions separated by opposing flap regions, the major rectangular planar region being sized to receive a plantar surface of the human foot with the minor rectangular planar region being sized to receive a hind foot region of the human foot, the opposing flap regions being sized to cover opposing ankle regions of the human foot, the rectangular planar regions and flap regions being formed of a pliable foam material so as to be foldable to encompass and envelope the entire foot;wherein the pliable foam material is an open-celled polyurethane foam material;wherein the top, contact region of the unitary blank has an adhesive applied thereto for restraining the unitary blank about the foot upon folding of the blank.2. The article of claim 1 , wherein the unitary blank is longitudinally dimensioned in a first direction to extend past the foot a sufficient length to be foldable back to provide an overlap region over a dorsal surface of the foot.3. The article of claim 2 , wherein the opposing flap ...

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Номер записи: 46
09-01-2020 дата публикации

ORTHOTIC DEVICE, ORTHOTIC SYSTEM AND METHODS OF MANUFACTURE AND USE THEREOF

Номер: US20200009288A1
Автор: Geremtzes Charalampos, Moustakas Dimitrios
Принадлежит:

An orthotic device for embracing and supporting a body part (e.g., articulation) of a human or animal. The orthotic device is a single sheet of moldable Polylactic Acid (PLA) material configured to maintain the body part in an optimal position for development and treatment. An orthotic system includes the PLA sheet and a protective layer in the form of a single moldable sheet of polyethylene foam (PEF). The PEF sheet is configured for placement between the PLA sheet and the body part. 1. An orthotic device comprising: a single sheet of moldable Polylactic Acid (PLA) material for embracing and supporting a body part of a human or animal comprising an articulation and configured to maintain the body part in an optimal position for development and treatment.2. The orthotic device of claim 1 , wherein the PLA sheet is formed with a plurality of perforations uniformly distributed over the total surface area of the PLA sheet.3. The orthotic device of claim 2 , wherein the perforations are distributed over 75% to 95% of the total surface area of the PLA sheet.4. The orthotic device of claim 2 , wherein the PLA sheet has a thickness in the range of about 1.5 mm to about 5.0 mm.5. The orthotic device of claim 2 , wherein the PLA sheet has a thickness in the range of about 1.5 mm to about 3.5 mm.6. The orthotic device of claim 2 , wherein the PLA sheet has a thickness in the range of about 1.8 mm to about 2.0 mm.7. The orthotic device of claim 2 , wherein the PLA sheet formed with at least one aperture for passage therethrough of a body part of the human or animal.8. The orthotic device of claim 1 , wherein the PLA sheet is pre-cut to a preselected configuration suitable for forming to shape for a custom application.9. The orthotic device of claim 1 , wherein the PLA sheet is 3D printed.10. An orthotic system comprising:a single sheet of moldable Polylactic Acid (PLA) material for embracing and supporting a body part of a human or animal comprising an articulation and ...

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Номер записи: 47
09-01-2020 дата публикации

COMPOSITIONS AND METHODS FOR PROMOTING HEMOSTASIS

Номер: US20200009289A1
Автор: MASKIEWICZ Richard, TORABINEJAD Mahmoud
Принадлежит: LOMA LINDA UNIVERSITY HEALTH

In one aspect, compositions for promoting hemostasis are provided. In some embodiments, the composition comprises a porous non-fibrous substrate impregnated with a hemostatic agent, wherein the porous non-fibrous substrate comprises a hydrophilic polyurethane foam. Methods of promoting hemostasis in a subject using such compositions, and methods of manufacturing such compositions, are also provided. 1. A composition for promoting hemostasis , the composition comprising: a porous non-fibrous substrate impregnated with a hemostatic agent , wherein the porous non-fibrous substrate comprises a hydrophilic polyurethane foam.2. The composition of claim 1 , wherein the hemostatic agent is a vasoconstrictor or a chemical cauterizing agent.3. The composition of claim 2 , wherein the vasoconstrictor is epinephrine.4. The composition of claim 3 , wherein the composition comprises epinephrine in an amount from about 0.45 mg to about 0.75 mg.5. The composition of claim 2 , wherein the chemical cauterizing agent is ferric sulfate or calcium sulfate.611.-. (canceled)12. A method of manufacturing a composition for promoting hemostasis claim 2 , the method comprising:applying an aqueous solution comprising a hemostatic agent onto a surface of a porous non-fibrous substrate comprising a hydrophilic polyurethane foam, wherein the aqueous solution is absorbed by the substrate.1314.-. (canceled)15. The method of claim 12 , wherein the hemostatic agent is a vasoconstrictor or a chemical cauterizing agent.16. The method of claim 12 , wherein the hemostatic agent is a vasoconstrictor.17. The method of claim 12 , wherein the hemostatic agent is epinephrine.18. The method of claim 12 , wherein the aqueous solution further comprises an antioxidant.19. The method of claim 18 , wherein the antioxidant is sodium metabisulfate.2025.-. (canceled)26. The method of claim 12 , wherein after the applying step claim 12 , the method further comprises removing essentially all water from the porous non- ...

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Номер записи: 48
19-01-2017 дата публикации

WOUND CARE COMPOSITIONS

Номер: US20170014542A1
Автор: Day Delbert E., Jung Steven B.
Принадлежит: The Curators of the University of Missouri

Glass-based particles of a biocompatible material which comprises 40 to about 80 wt % borate (BO) intermixed into a carrier which is an ointment, cream, or surgical glue. 1. Glass-based particles of a biocompatible material intermixed into a carrier ,{'sub': 2', '3, 'wherein the glass-based particles comprise from 40 to about 80 wt % BO;'}wherein the carrier is a biocompatible ointment or cream or a surgical glue.2. The glass-based particles intermixed into a carrier of claim 1 , wherein the glass-based particles comprise one or more alkali oxides selected from the group consisting of LiO claim 1 , NaO claim 1 , KO claim 1 , and RbO claim 1 , and one or more alkaline earth oxides selected from the group consisting of MgO claim 1 , SrO claim 1 , BaO claim 1 , and CaO.3. The glass-based particles intermixed into a carrier of claim 1 , wherein the glass-based particles comprise from about 50 to about 80 wt % BO.4. The glass-based particles intermixed into a carrier of claim 1 , wherein the glass-based particles comprise from about 5 to about 20 wt % of one or more alkali oxides selected from the group consisting of LiO claim 1 , NaO claim 1 , KO claim 1 , and RbO claim 1 , and from about 5 to about 40 wt % of one or more alkaline earth oxides selected from the group consisting of MgO claim 1 , SrO claim 1 , BaO claim 1 , and CaO.5. The glass-based particles intermixed into a carrier of wherein the glass-based particles further comprise one or more trace elements selected from the group consisting of Ag claim 1 , Cu claim 1 , F claim 1 , Fe claim 1 , Mn claim 1 , Mo claim 1 , Ni claim 1 , Sr claim 1 , and Zn in a concentration between about 0.05 and 10 wt % per trace element chemically dissolved in glass.6. The glass-based particles intermixed into a carrier of wherein the glass-based particles further comprise one or more trace elements selected from the group consisting of Ag claim 4 , Cu claim 4 , F claim 4 , Fe claim 4 , Mn claim 4 , Mo claim 4 , Ni claim 4 , Sr ...

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Номер записи: 49
19-01-2017 дата публикации

Poly(Meth)Acrylic Acid (Salt)-Based Particulate Absorbent, and Production Method

Номер: US20170014801A1
Автор: Adachi Yoshifumi, IKEUCHI Yoshitaka
Принадлежит:

[Problem] To provide, at low cost, a disposable diaper that presents no difficulties in disposable diaper manufacture in humid climates, and that has a minimal amount of flowback, and rapid absorption time. 1. A particulate water-absorbing agent comprising a poly (meth)acrylic acid (salt)-based water-absorbing resin as a main component , whereinthe particulate water-absorbing agent has:a particle size distribution of a weight average particle diameter of 300 to 500 μm,a blocking ratio after moisture absorption when left for one hour at 25° C. and 90% relative humidity of 20% or less,a surface tension of 60 mN/m or more, anda gel capillary absorption (GCA) of 28.0 g/g or more.2. The particulate water-absorbing agent according to claim 1 , wherein the particulate water-absorbing agent is surface crosslinked.3. The particulate water-absorbing agent according to claim 1 , wherein the particulate water-absorbing agent has a fluid retention capacity without pressure (CRC) of 28 g/g or more.4. The particulate water-absorbing agent according to claim 1 , wherein the particulate water-absorbing agent has a fluid retention capacity under pressure (AAP) of 25 g/g or more.5. The particulate water-absorbing agent according to claim 1 , wherein the particulate water-absorbing agent has a water absorption time by Vortex method of 40 seconds or less.6. The particulate water-absorbing agent according to claim 1 , wherein the particulate water-absorbing agent has a surface tension of 65 mN/m or more.7. The particulate water-absorbing agent according to claim 1 , wherein the particulate water-absorbing agent has a gel capillary absorption (GCA) of 30.0 g/g or more.8. The particulate water-absorbing agent according to claim 1 , comprising water-insoluble inorganic fine particles.9. The particulate water-absorbing agent according to claim 8 , wherein the water-insoluble inorganic fine particles content is from 0.01 to 1.0% by weight per 100% by weight of the polyacrylic acid (salt)- ...

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Номер записи: 50
17-01-2019 дата публикации

A NANOBIOCOMPOSITE FORMULATION FOR WOUND HEALING AND A PROCESS FOR THE PREPARATION THEREOF

Номер: US20190015468A1
Автор: Kumari Avnesh, Singla Rubbel, Yadav Sudesh Kumar
Принадлежит:

The present invention involves the isolation of plant based CNCs from the leaves of . For the formation of NCs, a novel greener approach using LE as reducing agent for in situ impregnation of AgNPs as fillers into CNCs as matrix is reported. The silver nitrate solution in three different concentrations of 1 mM, 5 mM and 10 mM was used to form NCs where AgNPs have been incorporated into CNCs matrix. The CNCs and NCs were characterized using SEM, TEM, XRD, Zeta potential, FT-IR, and UV-Vis spectroscopy. NCs developed in the form of film and ointment showed strong antimicrobial activity against both gram negative and gram positive bacteria. NCs wound dressing is capable of regulating wound exudates and providing moisture to wound responsible for faster healing of acute wounds. The observations from histopathological and biochemical assays confirmed that NCs enhance healing because of lesser inflammation, rapid angiogenesis, early collagen formation and enhanced rate of reepithelization. 1Syzygium cumini. A nanobiocomposite formulation (NCs) in ointment form comprising silver nanoparticles (AgNPs) and cellulose nanocrystals (CNCs) wherein the ratio of AgNPs and CNCs is in the range of 0.067%-0.4% w/w AgNPs: 7-8% w/w CNCs , and wherein the cellulose is derived from leaves.2. A process for the preparation of the nanobiocomposite formulation in ointment form as claimed in claim 1 , the method comprising:{'i': 'Syzygium cumini', 'a) treating washed and dried leaves with bleaching agent at pH in the range of 3.0-4.0 for a time period ranging between 2-3 h at a temperature ranging between 70-100° C. to obtain a bleached fibrous material;'}b) filtering and washing the bleached fibrous material as obtained from (a) followed by treating with acidified bleaching agent solution at a temperature ranging between 22-30° C. for a time period ranging 16-18 h to obtain acidified fibrous material;c) washing the acidified fibrous material as obtained from (b) followed by keeping it into 2 ...

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Номер записи: 51
21-01-2021 дата публикации

Products for treating inflammation, infections, disease, and malodors containing adsorbent porous carbonaceous material

Номер: US20210016243A1
Автор: Yonce Angela Jean
Принадлежит:

The present invention includes the composition and manufacturing of a non-prescription consumer product to treat odor and various types of inflammations, infections, and diseases. It embodies a disposable absorbent or nonabsorbent article containing unbound/freely associating adsorbent porous carbonaceous material for the entrapment and/or treatment of odor, pathogens, and adverse biological by-products. The product form includes but is not limited to tampons, panty liners, incontinence pads, diapers, sanitary towels, swabs, balls, casts, pouches, bandages and/or plugs, which contain adsorbent porous carbonaceous material that effectively reduces or eliminates adverse situations sourcing from pathogens and harmful biological by-products, including but not limited to fungi, bacteria, viruses, and parasites. The article is used to treat malodor, yeast infections, vaginitis, sexually transmitted diseases, field bullet wound holes, tooth infections, nail-bed and cuticle infections, among others by way of internal insertion and/or complete covering the body cavity, wound, and/or affected areas, creating a clear and direct path for contact with pathogens and adverse biological by-products. 1. An absorbent article containing an unbound/freely associating adsorbent porous carbonaceous material for the entrapment , and/or treatment of odor , pathogens , and adverse biological by-products.2. The embodiments of the invention according to include but are not limited to the following forms: tampons claim 1 , panty liners claim 1 , incontinence pads claim 1 , diapers claim 1 , sanitary towels claim 1 , swabs claim 1 , balls claim 1 , pouches claim 1 , paste-encased casts claim 1 , bandages and/or plugs.3. The embodiments of the invention according to claim 1 , wherein the adsorbent porous carbonaceous material being any form of activated carbon derived from claim 1 , but not limited to claim 1 , bamboo claim 1 , coconut husk claim 1 , willow peat claim 1 , wood claim 1 , coir ...

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Номер записи: 52
21-01-2021 дата публикации

Permeable Superabsorbent and Process for Production Thereof

Номер: US20210016247A1
Автор: Bauduin Christophe, Daniel Thomas
Принадлежит:

A highly permeable superabsorbent is prepared by a process comprising 1. A process for producing a superabsorbent , comprisingpolymerizing an aqueous monomer solution comprisinga) at least one ethylenically unsaturated monomer which bears an acid group and optionally is at least partly in salt form,b) at least one crosslinker,c) at least one initiator,d) optionally one or more ethylenically unsaturated monomer copolymerizable with the monomer mentioned under a), ande) optionally one or more water-soluble polymer;drying a resulting polymer,optionally grinding the dried polymer and sieving the ground polymer,optionally surface postcrosslinking the dried and optionally ground and sieved polymer,wherein, after drying, grinding, or sieving, and, if surface postcrosslinking is conducted, during or after the surface postcrosslinking, adding an x-ray-amorphous aluminum hydroxide powder.2. The process according to claim 1 , wherein 0.01% to 2% by weight claim 1 , based on the amount of polymer prior to the addition claim 1 , of x-ray-amorphous aluminum hydroxide is added.3. The process according to claim 2 , wherein 0.2% to 1% by weight claim 2 , based on the amount of polymer prior to the addition claim 2 , of x-ray-amorphous aluminum hydroxide is added.4. The process according to any of claim 1 , wherein the dried and optionally ground and sieved polymer is surface postcrosslinked with a postcrosslinker that forms covalent bonds with polar groups at a surface of the superabsorbent particles.5. The process according to any of claim 1 , wherein claim 1 , after the addition of x-ray-amorphous aluminum hydroxide powder claim 1 , 0.1% to 10% by weight claim 1 , based on the amount of polymer prior to the addition of the x-ray-amorphous aluminum hydroxide powder claim 1 , of water is added to the superabsorbent.6. A superabsorbent obtained by the process of any of .7. An article for absorption of fluids claim 6 , comprising the superabsorbent of .8. A process for producing ...

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Номер записи: 53
22-01-2015 дата публикации

Method for providing a localized dwell in an advancing web

Номер: US20150020950A1
Автор: Paul Anthony Kawka, Uwe Schneider
Принадлежит: Procter and Gamble Co

A method for dwelling a portion of a web is disclosed. A web can be conveyed at a first velocity by an apparatus comprising a first traversing guide and a second traversing guide operatively connected in a fixed spatial relationship. The first traversing guide and the second traversing guide can be moveable from a start position in a substantially linear path. The first traversing guide and the second traversing guide can be moved in a first direction at a second velocity equal to about one half the first velocity for a dwell time. One or more processing stations can bond the at least two layers of the web. The first traversing guide and the second traversing guide can be accelerated and decelerated in a second direction opposite the first direction until the first traversing guide and the second traversing guide are returned to the start position in a return time.

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Номер записи: 54
28-01-2016 дата публикации

Methods and Compositions for Promoting Wound Healing

Номер: US20160022735A1
Автор: Burnley Victoria V., Capomacchia Anthony C., Kemp Douglas T., Ritchie Branson W., Wooley Richard E.
Принадлежит:

The present invention provides methods and compositions that use the combination of Tris and EDTA to inhibit the growth of microorganisms at the site of a wound or burn, and/or to promote the healing of a wound or burn, and/or to reduce the sensation of pain at the site of a wound or burn. The amount of Tris and EDTA applied to a wound or burn can be selected to achieve one or more of the foregoing effects. 180-. (canceled)81. A composition consisting of Tris , EDTA , and dissolved silver in a pharmaceutically acceptable carrier selected from the group consisting of water , saline , physiological saline , an ointment , a cream , an oil-water emulsion , and a gel , wherein the Tris , EDTA , and dissolved silver are in amounts sufficient to promote healing of a burn on a mammalian , bird , or reptile body , the composition consisting of a pH of from 6.0 to 9.0 , and optionally , a detergent , a vitamin , an anti-inflammatory agent , lecithin , glycerin , methyl paraben , aloe vera , polypropylene glycol ethoxylate , and/or poloxamer 407.82. The composition according to wherein the detergent is from 1% to 30% of the composition by volume/volume.83. The composition according to wherein the silver is at a concentration of from 1 ppm to 300 ppm.84. The composition according to wherein the silver is at a concentration of from 1 ppm to 50 ppm.85. The composition according to wherein the EDTA is at a concentration of from 1 mM to 250 mM.86. The composition according to wherein the Tris is at a concentration of from 10 mM to 250 mM.87. A composition consisting of Tris claim 81 , EDTA claim 81 , and dissolved silver in a pharmaceutically acceptable carrier selected from the group consisting of water claim 81 , saline claim 81 , physiological saline claim 81 , an ointment claim 81 , a cream claim 81 , an oil-water emulsion claim 81 , and a gel claim 81 , wherein the Tris claim 81 , EDTA claim 81 , and dissolved silver are in amounts sufficient to promote healing of a wound on a ...

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Номер записи: 55
26-01-2017 дата публикации

ABSORBENT ANTIMICROBIAL WOUND DRESSINGS

Номер: US20170021050A1
Автор: Carlsson Erik, Hansson Dennis
Принадлежит:

The present invention provides methods for preparing an absorbent antimicrobial wound dressing which comprise steps of (a) preparing an antimicrobial coating composition by mixing an antimicrobial agent and one or more polymers in a solvent system that comprises a non-aqueous solvent, (b) contacting the antimicrobial coating composition of step (a) with a wound dressing substrate which comprises absorbent fibers or absorbent particles, and (c) drying the product of step (b). The present invention also provides absorbent antimicrobial wound dressings including those prepared by these methods as well as antimicrobial coating compositions and methods of producing antimicrobial coating compositions. 1. A method of preparing an absorbent antimicrobial wound dressing comprising:(a) preparing an antimicrobial coating composition by mixing an antimicrobial agent and one or more polymers in a solvent system that comprises a non-aqueous solvent;(b) contacting the antimicrobial coating composition of step (a) with a wound dressing substrate which comprises absorbent fibers or absorbent particles; and(c) drying the product of step (b).2. The method of wherein the one or more polymers are selected from the group consisting of cellulosic polymers claim 1 , neutral poly(meth)acrylate esters claim 1 , polyvinylpyrrolidone claim 1 , polyvinylpolypyrrolidone claim 1 , and combinations thereof.3. The method of claim 1 , wherein the absorbent fibers comprise polyvinyl alcohol.4. The method of claim 3 , wherein the polyvinyl alcohol is cross-linked.5. The method of claim 1 , wherein the absorbent fibers comprise a cellulosic polymer.6. The method of claim 5 , wherein the absorbent fibers comprise carboxymethyl cellulose.7. The method of claim 1 , wherein the one or more polymers in the antimicrobial coating composition have an average molecular weight between 50-1500 kDa.8. The method of claim 1 , wherein the one or more polymers in the antimicrobial coating composition are cellulosic ...

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Номер записи: 56
10-02-2022 дата публикации

ODOR/TOXIN-ABSORBING SANITARY PADS, PANTY LINERS, AND TAMPONS

Номер: US20220040368A1
Автор: Halevi Quadesha
Принадлежит:

An odor and menses absorption device includes a user contact layer and at least one adjoining super absorbent core layer. Fluid can move from the user contact layer to the super absorbent core layer. The user contact layer contains a blend of polylactic acid fiber and bamboo charcoal fiber and acts as a barrier to fluids with a surface tension greater than 30 dynes. 1. An odor and menses absorption device comprising:a user contact layer containing a blend of polylactic acid fiber and bamboo charcoal fiber; andat least one super absorbent core layer adjoining the user contact layer and in fluid communication therewith;wherein the user contact layer is operative as a barrier to fluids with a surface tension greater than 30 dynes.2. The odor and menses absorption device of claim 1 , wherein the user contact layer further comprises casein fiber.3. The odor and menses absorption device of claim 1 , configured as a tampon.4. The odor and menses absorption device of claim 1 , further comprising:a polyethylene base layer,wherein the polyethylene base layer is air-permeable and water vapor-permeable, andwherein the at least one super absorbent core layer is sealed between the user contact layer and the polyethylene base layer.5. The odor and menses absorption device of claim 4 , further comprising:an adhesive layer adhered to an external surface of the polyethylene base layer; anda release layer removably attached to the adhesive layer.6. The odor and menses absorption device of claim 5 , further comprising a pair of scalloped ends.7. The odor and menses absorption device of claim 5 , configured as a panty liner.8. The odor and menses absorption device of claim 5 , configured as a sanitary napkin.9. The odor and menses absorption device of claim 8 , further comprising lateral flaps. This application claims the benefit of priority of U.S. provisional application No. 62/706,208, filed Aug. 5, 2020, the contents of which are herein incorporated by reference.The present ...

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Номер записи: 57
24-01-2019 дата публикации

OXYGEN-GENERATING COMPOSITIONS FOR ENHANCING CELL AND TISSUE SURVIVAL IN VIVO

Номер: US20190022021A1
Автор: Atala Anthony, Harrison Benjamin C., Yoo James J.
Принадлежит:

A method of treating hypoxic tissue such as wound tissue comprises contacting a composition to the hypoxic tissue in a hypoxia-treatment effective amount, the composition comprising a biodegradable polymer and an inorganic peroxide incorporated into the polymer. 1. A method of treating hypoxic tissue in need thereof , comprising contacting a composition to said hypoxic tissue in a hypoxia-treatment effective amount , wherein said composition comprises a biodegradable polymer and an inorganic peroxide in solid form incorporated into said polymer , and wherein said hypoxic tissue is wound tissue , tissue afflicted with an anaerobic infection or cancer tissue.2. The method of claim 1 , wherein said hypoxic tissue is in vivo in a subject in need of said treatment.3. The method of claim 1 , wherein said tissue is wound tissue and said composition is administered in an amount effective to facilitate the healing of said wound tissue.4. The method of claim 2 , further comprising the step of concurrently treating said wound tissue with negative pressure wound therapy.5. The method of claim 1 , wherein said tissue is afflicted with an anaerobic infection and said composition is administered in an amount effective to treat said infection.6. The method of claim 1 , wherein said tissue is cancer tissue and said composition is administered in an amount effective to treat said cancer.7. The method of claim 1 , wherein said composition is in the form of a sheet material claim 1 , and said contacting step is carried out by contacting said sheet material to said tissue.8. The method of claim 1 , wherein said composition is in the form of injectable microparticles claim 1 , and said contacting step is carried out by injecting said microparticles into said tissue.9. The method of claim 1 , wherein said composition is in the form of a spray claim 1 , and said contacting step is carried out by spraying said composition onto said tissue.10. The method of claim 1 , wherein said composition ...

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Номер записи: 58
24-01-2019 дата публикации

MOLECULAR TARGETS FOR THE TREATMENT OF WOUNDS, IN PARTICULAR CHRONIC WOUNDS

Номер: US20190022097A1
Автор: Darzacq Xavier, Dugast-Darzacq Claire, Noizet Maïté, Spiluttini Hebert Beatrice
Принадлежит:

The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes and/or an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds. 119.-. (canceled)20. A method for treating wounds , preferably chronic wounds , in a subject in need thereof , comprising administering to said subject a therapeutic compound comprising:an agent that inhibits the activity of at least one gene selected from the group consisting of MEOX2, SIX2, and homologues thereof having at least 50% identity with said genes, and/oran agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, GLI1, preferentially EGR2, STAT4 and homologues thereof having at least 50% identity with said gene.21. The method according to further comprising:an agent that inhibits the activity of PPARG or homologues thereof having at least 50% identity with PPARG; and/oran agent that enhances the activity of at least one gene selected from the group consisting of SMAD3, SMAD4 and homologues thereof having at least 50% identity with said genes.22. The method according to wherein said agent is selected from the group consisting of: anti-sense DNA or RNA claim 20 , siRNA claim 20 , shRNA claim 20 , cDNA claim 20 , TALENS or ribozymes claim 20 , either naked or in the form of plasmid or viral vectors.23. The method according to wherein said agent is an inhibitor or enhancer of protein function.24. The method according to wherein said agent is selected from the group consisting of: a binding agent that binds claim 23 , either ...

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Номер записи: 59
25-01-2018 дата публикации

POLYELECTROLYTE COMPLEXES

Номер: US20180023044A1
Автор: HEYMANN JARED, KINSINGER MICHAEL, Scheuing David R., Smith William L.
Принадлежит: The Clorox Company

The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide a cleaning benefit and surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellency, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions and at least one oxidant selected from the group: alkaline metal salts and/or alkaline earth metal salts of hypochlorous acid, hypochlorous acid, solubilized chlorine, any source of free chlorine, acidic sodium chlorite, active chlorine generating compound and any combinations or mixtures thereof. Also provided are means to form stable associative polyelectrolyte complexes with at least one oxidant in aqueous solutions having R values from about 0.10 to 20. 1. A treatment composition comprising:(i) water;(ii) an amphoteric surfactant;(iii) at least one water-soluble associative polyelectrolyte complex comprising a water soluble cationic first polyelectrolyte; and a water soluble second polyelectrolyte bearing groups of opposite charge to said first polyelectrolyte; wherein the resulting water-soluble associative polyelectrolyte complex is non-precipitating in the treatment composition, wherein R, the molar ratio of charged groups present on said first polyelectrolyte to oppositely charged groups present on said second polyelectrolyte is from about 0.10 to 20;(iv) wherein said cationic first polyelectrolyte and said second polyelectrolyte each comprise at least one of homopolymers, ...

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Номер записи: 60
25-01-2018 дата публикации

METHOD FOR PREPARING PBAT LAMINATED MEMBRANE COMPOSITE MATERIAL AND USES

Номер: US20180023181A1
Автор: XING Peng
Принадлежит: SHANDONG BENEFIT NEW MATERIAL CO., LTD.

A method for preparing a PBAT laminated membrane composite material uses PBAT or a material with PBAT as the main component and other biodegradable plastic or superfine calcium carbonate in a mixture. The temperature of the mixture is increased by means of a lamination machine segment by segment, the material is heated slowly to a molten state, and the temperature of a rolling shaft is controlled by introducing cold water to the rolling shaft when the lamination machine conducts membrane lamination, so that the temperatures of rolling wheels and the laminated membrane are controlled. 1. A method for preparing a PBAT film composite , comprising the following steps:{'b': '1', 'I. putting PBAT or a mixture of 100 weight parts of PBAT and 5-40 weight parts of a biodegradable plastic or 5-40 weight parts of super-fine calcium carbonate, as a base stock, into a mixing tank (), mixing, heating and drying the base stock;'}{'b': 3', '2, 'II. conveying the base stock dried in step I to a storage bin () of a coating machine by a raw material conveyor ();'}{'b': 3', '4', '5', '5', '5', '7', '6, 'III. sending the base stock in the storage bin () from step II into the coating machine via a feed port (), heating and pushing the base stock using a screw (), wherein the coating machine is divided into a plurality of heating segments along a direction of the screw (), and temperatures of the heating segments gradually rise to the melting point of the base stock along the direction of the screw (), and sending the melted base stock to a coating tool () of the coating machine via a material conveying elbow ();'}{'b': 15', '16', '15', '7', '10', '15', '7', '12', '11', '7', '10', '15', '15', '18', '10', '7, 'VI. pushing a coating machine table () to a certain position by using advance guide wheels () at a bottom of the coating machine table () such that the coating tool () as described in step III is positioned between two rollers () of the coating machine table (), turning the coating ...

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Номер записи: 61
28-01-2021 дата публикации

COMPOSITION AND DRESSING WITH NITRIC OXIDE

Номер: US20210023262A1
Автор: Araya Abraham, Broderick Sonya Theresa, Minihan Alan Reginald, Robbins Paul Matthew, Waring Michael J.
Принадлежит:

A dressing composition for use as a skin dressing comprises an elastomeric-adhesive composition, and a zeolite comprising releasably adsorbed nitric oxide. The zeolite may comprise a transition metal cation such as Co, Fe, Mn, Ni, Cu, Zn, Ag or a mixture thereof as an extra-framework metal cation, preferably Zn. The elastomeric adhesive composition may be a hydrocolloid-adhesive composition comprising, hydrocolloid and elastomer. The dressing composition releases nitric oxide, which may have beneficial effects, when used on wounds or moist skin, with a substantially constant release rate over a long period of time. A dressing including a layer of the dressing composition has a backing layer and may have a release liner removably attached to the skin-contacting surface of the dressing layer. 117-. (canceled)18. A nitric oxide-releasing dressing composition for use as a skin dressing comprising:i) between 30% and 96% by weight of an elastomeric-adhesive composition, andii) between 4% and 70% by weight of a zeolite dispersed within the elastomeric-adhesive composition, said zeolite comprising releasably adsorbed nitric oxide and a zinc metal cation as an extra-framework metal cation providing positive charge,wherein the dressing composition releases nitric oxide at a generally uniform rate over an extended time period.19. The composition of claim 18 , comprising between 30% and 90% by weight of an elastotneric-adhesive composition claim 18 , and from 10% to 70% by weight of zeolite.20. The composition of claim 18 , wherein the zeolite is selected from the group consisting of zeolite P claim 18 , zeolite A claim 18 , zeolite X claim 18 , zeolite Y and mixtures thereof.21. The composition of claim 18 , wherein 20 molar % or more of the extra framework cation of the zeolite is a zinc metal cation.22. The composition of claim 18 , wherein 50 molar % or more of the extra framework cation of the zeolite is a zinc metal cation.23. The composition of claim 18 , wherein the ...

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Номер записи: 62
02-02-2017 дата публикации

ABSORBENT PRODUCT COMPRISING AN ODOR CONTROL MATERIAL

Номер: US20170027779A1
Автор: Gustafson Ingrid, Stridfeldt Chatrine
Принадлежит: SCA HYGIENE PRODUCTS AB

Absorbent product having a liquid permeable surface and a liquid impermeable opposite surface, the absorbent product including an odor control material, the odor control material including a carrier material and a plurality of odor control particles adhered to the carrier material. The carrier material has a first surface located towards the liquid permeable surface of the absorbent product and a second opposite surface located towards the liquid impermeable surface of the absorbent product. The plurality of odor control particles are bonded to the second surface of the carrier material with a water soluble binder substance wherein the binder substance at least partly dissolves when in contact with an aqueous solution. 2. Absorbent product according to claim 1 , wherein the water-soluble binder substance has a molecular weight of 40 kDa or lower.3. Absorbent product according to claim 2 , wherein the water-soluble binder substance comprises a hydrophilic polymer.4. Absorbent product according to claim 2 , wherein the water-soluble binder substance comprises a hydrophilic low molecular weight compounds.5. Absorbent product according to claim 1 , wherein the first surface of the carrier material is treated with surfactant(s).6. Absorbent product according to claim 1 , wherein the water-soluble binder substance comprises an additive selected from the group of plasticizer claim 1 , stabilizer claim 1 , agent improving dispersibility claim 1 , pH regulating agent claim 1 , antimicrobial substance claim 1 , surfactant(s) claim 1 , and a mixture thereof.7. Absorbent product according to claim 1 , wherein the weight ratio binder substance to odor control particles is from 1:10 to 10:1.8. Absorbent product according to claim 1 , wherein the carrier material is a nonwoven material.9. Absorbent product according to claim 1 , wherein the carrier material is a foam material.10. Absorbent product according to claim 1 , wherein the odor control material covers 5-100% of the total ...

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Номер записи: 63
01-02-2018 дата публикации

METHODS AND COMPOSITIONS FOR WOUND HEALING

Номер: US20180028713A1
Автор: "OKeefe Anna M.", Abbott Nicholas L., Agarwal Ankit, Crawford Eric, Nelson Tyler B., Pranami Gaurav
Принадлежит:

The present invention relates to large scale manufacture of nanoscale microsheets for use in applications such as wound healing or modification of a biological or medical surface. 1. A process for manufacture of an article comprising:a) providing a flexible substrate comprising a low surface energy surface having a surface area of greater than 0.1 square meters;b) depositing a nanoscale polymer layer from about 0.5 nm to 10000 nm thick on the low surface energy surface; andc) introducing a bioactive agent into the nanoscale polymer layer to provide a bioactive nanoscale polymer layer.2. The process of claim 1 , wherein the depositing occurs via a roll to roll coating process.3. The process of claim 2 , wherein the roll to roll coating process comprises transferring the flexible substrate from a first roll to at least a second roll and coating the low surface energy surface of the flexible substrate with the nanoscale polymer layer while the flexible substrate is being transferred between the first roll and the second roll.4. The process of claim 1 , wherein the nanoscale polymer layer is deposited on the low surface energy surface of the flexible substrate by a coating or printing method selected from the group consisting of roll to roll coating claim 1 , spray coating claim 1 , dip coating claim 1 , immersion coating claim 1 , spin coating claim 1 , slot die coating claim 1 , inkjet coating claim 1 , anilox coating claim 1 , screen coating claim 1 , offset lithography printing claim 1 , flexographic coating claim 1 , gravure coating claim 1 , rotogravure coating claim 1 , reverse roll coating claim 1 , metering (Meyer) rod coating claim 1 , blade coating claim 1 , knife over roll coating claim 1 , air knife coating claim 1 , curtain coating claim 1 , melt extrusion coating claim 1 , solvent casting and any combinations thereof.5. The process of claim 1 , wherein the nanoscale polymer layer is formed by depositing alternating layers of at least one positively ...

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Номер записи: 64
31-01-2019 дата публикации

Water-Absorbent Core Production System

Номер: US20190029892A1
Автор: Chen Jianhui
Принадлежит:

A production system of a water-absorbent core. The supplying component thereof is configured to convey the fluffy cotton to the starting end of the transmission component, and the plurality of outlets of the supplying component for conveying the mixture of the fluff pulp and the hot-melt fibers to the transmission component are all located in the middle portion of the transmission component, the feeding port for conveying the super absorbent polymer to the transmission component and the outlets are arranged alternately along the transmitting direction of the transmission component, and each feeding port is located between the two outlets; the vacuum adsorption device can cause the mixture to be absorbed on the transmission component; the hot air penetration device performs hot air penetration treatment on the laminate; and the ultrasonic cutting device of the slitting mechanism is configured to ultrasonically cut the laminate after the hot air penetration treatment. 1. A production system of a water-absorbent core , comprising: a manufacturing mechanism and a slitting mechanism , the manufacturing mechanism comprising a transmission component , a conveying component , a supplying component , a feeding component , a vacuum adsorption device , and a hot air penetration device , wherein:the conveying component is configured to convey fluffy cotton to a starting end of the transmission component;the supplying component is configured to convey a mixture of fluff pulp and hot-melt fibers to the transmission component, the transmission component has a plurality of outlets, and the plurality of outlets are located in a middle portion of the transmission component;the feeding component is configured to convey a super absorbent polymer to the transmission component, the feeding component has a plurality of feeding ports, the plurality of feeding ports and the plurality of outlets are arranged alternately along a transmitting direction of the transmission component, and each ...

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Номер записи: 65
30-01-2020 дата публикации

HEMOSTATIC SPONGE

Номер: US20200030481A1
Автор: HEDRICH HANS CHRISTIAN, HOEFINGHOFF JORIS
Принадлежит:

The present invention provides a hemostatic porous composite sponge comprising: 1. A method of manufacturing a hemostatic composite , comprising:contacting a sponge comprising a matrix of a biomaterial in dried form with a reactive polymeric material in the form of a solution so that the biomaterial is impregnated with the reactive polymeric material or the reactive polymeric material is coated onto a surface of the matrix of the biomaterial, or both; anddrying the contacted biomaterial and reactive polymeric material.2. A hemostatic composite comprising a sponge comprising a matrix of a biomaterial that is impregnated with a reactive polymeric material obtained by the method of .3. A hemostatic composite comprising a sponge comprising a matrix of a biomaterial that is coated with a reactive polymeric material obtained by the method of .4. The method of claim 1 , wherein the reactive polymeric material is a reactive hydrophilic polymeric material.5. The method of claim 1 , wherein the reactive polymeric material is a single reactive hydrophilic polymeric material.6. The method of claim 1 , wherein the reactive polymeric material is a single hydrophilic polymeric material comprising electrophilic reactive groups claim 1 , wherein the hydrophilic polymeric material is a hydrophilic crosslinker.7. The method of claim 1 , wherein the reactive polymeric material comprises a polyethylene glycol (PEG).8. The method of claim 1 , wherein the reactive polymeric material comprises a polyethylene glycol (PEG) comprising two or more reactive groups selected from the group consisting of succinimidyl esters (—CON(COCH)) claim 1 , aldehydes (—CHO) claim 1 , and isocyanates (—N═C═O).9. The method of claim 1 , wherein the biomaterial is impregnated with the reactive polymeric material.10. The method of claim 1 , wherein the reactive polymeric material is coated onto a surface of the matrix of the biomaterial. This application is a divisional of U.S. patent application Ser. No. 14/184 ...

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Номер записи: 66
04-02-2021 дата публикации

DRAPE HAVING MICROSTRAIN INDUCING PROJECTIONS FOR TREATING A WOUND SITE

Номер: US20210030598A1
Автор: Coulthard Richard Daniel John, Locke Christopher Brian, Robinson Timothy Mark, Tout Aidan Marcus
Принадлежит:

Systems and apparatuses for administering reduced pressure treatment to a tissue site include a reduced pressure source, a drape having a plurality of projections for contacting the tissue site, and an adhesive connected to at least a portion of the drape for sealing the drape to a portion of a patient's intact epidermis. 1. A system for providing reduced pressure wound therapy to a tissue site , comprising:a drape configured to be disposed over the tissue site to create a sealed space between the drape and the tissue site;a reduced pressure source in fluid communication with the sealed space;a sensor in fluid communication with the sealed space; anda processing unit operatively coupled to the sensor;wherein the processing unit is configured to determine a real-time rate of pressure decay based on data from the sensor.2. The system of claim 1 , wherein the decay is determined by measuring an amount of time required for pressure at the sealed space to drop below a threshold pressure.3. The system of claim 1 , further comprising a vent fluidly coupled to the sealed space by a conduit.4. The system of claim 3 , wherein the decay in reduced pressure is determined by measuring a reduction in a flow rate in the conduit over a selected amount of time after opening the vent.5. The system of claim 1 , wherein the processing unit is configured to send an alert signal when the drape needs to be changed.6. The system of claim 1 , wherein the processing unit is configured to:calculate a pressure-time curve based on a time required to reach a set pressure at the sealed space;determine, based on a shape of the pressure-time curve, whether the drape needs to be changed due to an accumulation of slough or a growth of granulation tissue.7. The system of claim 1 , wherein the drape comprises a substantially gas impermeable claim 1 , flexible sheet.8. The system of claim 7 , wherein the drape comprises a plurality of projections extending from a tissue-facing side.9. The system of ...

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Номер записи: 67
05-02-2015 дата публикации

LIQUID-PERMEABLE PRIMARY DRESSING HAVING A FRACTION OF HEAVY METAL

Номер: US20150037392A1
Автор: Riesinger Birgit
Принадлежит:

The present invention relates to a fluid-permeable primary dressing in strip form, having pores, perforations or honeycomb lattices, which enable the passage of fluid, further having a content of at least one heavy metal present in elemental or ionic form. 1. A fluid-permeable primary dressing in strip form , comprising: a plurality of pores , perforations or honeycomb lattices , wherein the plurality of pores , perforation , or honeycomb lattices enable the passage of fluid through the fluid-permeable primary dressing; and at least one heavy metal present in elemental or ionic form disposed within the fluid-permeable primary dressing.2. The primary dressing as claimed in claim 1 , wherein the at least one heavy metal present in elemental or ionic form is selected from the group comprising copper claim 1 , zinc and/or silver.3. The primary dressing as claimed in claim 2 , wherein the primary dressing comprises a film having pores and/or perforations.4. The primary dressing as claimed in claim 3 , wherein the plurality of pores claim 3 , perforations or honeycomb lattices are made in three-dimensional form.5. The primary dressing as claimed in claim 4 , characterized in that the primary dressing comprises a gauze or a fabric including the plurality of pores claim 4 , perforations or honeycomb lattices.6. The primary dressing as claimed in claim 5 , wherein the primary dressing is a wound contact lattice.7. The primary dressing as claimed in claim 6 , wherein the at least one heavy metal present in elemental or ionic form are coated onto the primary dressing.8. The primary dressing as claimed in claim 7 , wherein at least one heavy metal present in elemental or ionic form is coextrued into the primary dressing.9. The primary dressing as claimed in claim 8 , wherein the primary dressing further comprises a plurality of punched holes claim 8 , slits claim 8 , incisions claim 8 , or recesses that serve to facilitate the passage of fluid.10. A wound dressing having a ...

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Номер записи: 68
07-02-2019 дата публикации

Sanitary Napkin

Номер: US20190038797A1
Автор: Van Kleef Paul Richard
Принадлежит:

A sanitary napkin, towel, or pad having one or more of Manuka honey, Tourmaline powder, Jade powder, Amethyst powder, or silver applied to or sewn into a layer of the napkin. 17-. (canceled)8. A sanitary napkin comprising:a first, liquid-pervious layer, said first layer having an upper surface and a lower surface;a second layer having an upper surface, a lower surface, and a first far infra-red emitting material, said first far infra-red material comprising Jade powder;a third layer comprising an absorbent material, said third layer having an upper surface and a lower surface; anda fourth, liquid-impervious layer, said fourth layer having an upper surface and a lower surface;wherein the upper surface of the second layer is adjacent to the lower surface of the first layer, and the upper surface of the third layer is adjacent to the lower surface of the second layer.9. The sanitary napkin of claim 8 , further comprising a fifth layer wherein said fifth layer comprises a sponge material and said fifth layer has an upper surface and a lower surface.10. The sanitary napkin of claim 9 , wherein the upper surface of the fifth layer is adjacent to the lower surface of the third layer claim 9 , and the upper surface of the fourth layer is adjacent to the lower surface of the fifth layer.11. The sanitary napkin of claim 8 , wherein the second layer further comprises a second far infra-red emitting material.12. The sanitary napkin of claim 11 , wherein the second far infra-red emitting material is tourmaline powder.13. The sanitary napkin of claim 8 , wherein the second layer further comprises silver.14. The sanitary napkin of claim 8 , wherein the fourth layer further comprises a second far infra-red emitting material.1520-. (canceled)16. The sanitary napkin of claim 12 , wherein the second layer further comprises silver.17. The sanitary napkin of claim 16 , wherein the silver comprises silver nanoparticles.18. The sanitary napkin of claim 13 , wherein the silver comprises ...

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Номер записи: 69
06-02-2020 дата публикации

MULTIFUNCTIONAL FORMULATION COMPRISED OF NATURAL INGREDIENTS AND METHOD OF PREPARATION/MANUFACTURING THEREOF

Номер: US20200038470A1
Автор: Datt Rajan, KUMAR RAMADHAR, Pandey Siddharth, Shrivastava Pallavi
Принадлежит:

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phytopharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment. 135-. (canceled)36. A flexible , biocompatible bandage dressing comprising:a biocompatible, porous matrix; and{'i': Emblica officinalis,', 'Camellia sinsensis, 'a dried, phytopharmaceutical formulation on the biocompatible, porous matrix, wherein said dried, phytopharmaceutical formulation has a thickness of between about 10 μm to 500 μm and comprises 0.5 to 20 percent of non-aqueous extract from the plant 1.0 to 20 percent of non-aqueous extract from the plant , and 0.1 to 12 percent of water soluble curcumin.'}37. The flexible claim 36 , biocompatible bandage dressing of claim 36 , wherein said dried claim 36 , phytopharmaceutical formulation comprises 0.2 to 12.0 percent of aloe vera gel.38. The flexible claim 37 , biocompatible bandage dressing of claim 37 , wherein said aloe vera gel comprises 0.5 to 9.0 percent tocopherol.39. The flexible claim 37 , biocompatible bandage dressing of claim 37 , wherein said aloe vera gel is derived from a 0.5 to 3.0 percent aloe vera solution and 1.0 to 10.0 percent nano-silver solution.40. The flexible claim 36 , biocompatible bandage dressing of claim 36 , comprising liposomes that encapsulate at least a portion of said phytopharmaceutical formulation claim 36 , said liposomes having a ...

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Номер записи: 70
15-02-2018 дата публикации

Multifunctional formulation comprised of natural ingredients and method of preparation/manufacturing thereof

Номер: US20180042980A1
Автор: Datt Rajan, KUMAR RAMADHAR, Pandey Siddharth, Shrivastava Pallavi
Принадлежит:

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment. 1. A ready to use , flexible , multifunctional biocompatible formulation and bandage dressing and a method of manufacturing thereof , said formulation and dressing comprising:a matrix based structure, having a plurality of biopolymers or synthetic polymers in the form of a formulation, with all ingredients working together in synergy, said matrix contained with the water soluble nano-form of non-aqueous solvent-extracted, water-insoluble phyto-pharmaceuticals from different natural sources; anda gel that is from herbal, animal or synthetic sources;such that the ingredients of formulation have much enhanced bioavailability than their naturally known values thus making it highly effective for wound healing, drug-delivery, anti-cancer therapy, anti-Alzheimer's and anti-multiple sclerosis.2Emblica officinalis, Acacia catechu, Azadirachta indica, Curcuma longa, Camellia sinsensis, Mimosa pudica, Ocimum sanctum, Phyllanthus emblica, Ricinus communis, Terminalia arjuna, Withania somnifera, Bacopa monnieriAloe vera. A ready to use claim 1 , flexible claim 1 , multifunctional biocompatible bandage dressing as claimed in claim 1 , wherein said plurality of biopolymers are selected from but not limited to etc claim 1 , combined with a ...

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Номер записи: 71
16-02-2017 дата публикации

POLYMER LAMINATE

Номер: US20170043062A1
Автор: Arakane Toru, Hochi Motonori, Komachi Takuya, Nagase Yu, Okamura Yosuke, Sekido Yuki
Принадлежит:

A polymer laminate has 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm that are laminated, the thickness of at least one of the outermost layers is 10 nm-180 nm, and the outermost layers are joined to each other. A polymer laminate excellent in biocompatibility and mechanical strength and suitable to medical applications such as wound dressings and antiadhesive materials can be obtained. 18.-. (canceled)9. A polymer laminate in which 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm are laminated , a thickness of at least one of outermost layers is 10 nm-180 nm , and said outermost layers are joined to each other.10. The polymer laminate according to claim 9 , wherein said at least one of outermost layers contains a polylactic acid-based resin.11. The polymer laminate according to claim 9 , wherein at least one layer of said layers having a thickness of 10 nm-400 nm contains a compound selected from the group consisting of a polysaccharide claim 9 , a polyvinyl alcohol and a polyvinyl alcohol copolymer.12. The polymer laminate according to claim 11 , wherein said polysaccharide is an alginate.13. The polymer laminate according to claim 9 , wherein a total thickness of the polymer laminate is 20 nm-1 claim 9 ,000 nm.14. The polymer laminate according to claim 9 , wherein a hydrophobic chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.15. The polymer laminate according to claim 9 , wherein a water soluble chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.16. The polymer laminate according to claim 9 , wherein particles having a particle diameter of 5 nm to 5 claim 9 ,000 nm are contained in at least one interlaminar part formed between said layers having a thickness of 10 nm-400 nm.17. The polymer laminate according to claim 10 , wherein at least one layer of said layers having a thickness of 10 nm- ...

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Номер записи: 72
15-02-2018 дата публикации

Multifunctional transdermal dressing for wounds

Номер: US20180043049A1
Автор: Krishnaswamy Kasthuri Rangan, Tirumalai Srinivas Sudarshan
Принадлежит: Materials Modification Inc

A multifunctional polymer-free clay products having a clay, a zwitterion, a silver compound, and, an analgesic. The multifunctional polymer-free clay product provides antimicrobial and pain relieving properties. Method of treatment of burns using the multifunctional polymer-free clay product having antimicrobial and pain relieving properties. Methods of preparing multifunctional polymer-free clay products having a clay, a zwitterion, a silver compound, and, an analgesic.

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Номер записи: 73
01-05-2014 дата публикации

Effective odor control with coatings of designed porous molecules

Номер: US20140121619A1
Автор: Evren Aslan-Guerel, Gert J. Claasen, Rudolf J. Koopmans, Scott T. Matteucci
Принадлежит: Dow Global Technologies LLC

The present invention relates to coatings for articles comprising a non-zeolitic silica mesoporous structure. The coatings of the present invention have shown an ability to effectively reduce odors.

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Номер записи: 74
03-03-2022 дата публикации

Sealant Dressing with Protected Reactive Components

Номер: US20220062492A1
Автор: Kosol Wilai, Liu Xuejun Jay, Llanos Gerard, Wang Yi-Lan Allen, Weindl Thomas
Принадлежит:

The present invention is directed to multi-layered wound dressings having a carrier layer, at least two sublayers, wherein each sublayer contains at least one reactive, cross-linkable component and the at least two reactive, cross-linkable components are co-reactive with the other and at least one reactive, cross-linkable has a protective leaving group and a buffering salt agent.

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Номер записи: 75
03-03-2022 дата публикации

ODOR-INHIBITING COMPOSITIONS AND HYGIENIC ARTICLES INCORPORATING THE SAME

Номер: US20220062494A1
Автор: Hoeller Olaf, LEPTICH Joseph, Mitchell Michael, RODRIGUEZ David J, WOLFE Michaela P.
Принадлежит:

Disclosed herein are embodiments of odor-inhibiting compositions and hygienic articles incorporating the same. In some embodiments, an odor-inhibiting composition comprises water-absorbing polymer particles; a first odor control agent comprising a chelation agent; and a second odor control agent.

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Номер записи: 76
14-02-2019 дата публикации

ABSORBENT ARTICLE

Номер: US20190046362A1
Автор: YAMADA Kikuo
Принадлежит:

In order to absorb a small amount of liquid, to prevent an absorbent article from being disintegrated by the absorbed liquid, and to prevent piping of a toilet from being clogged even if the absorbent article is flushed into a flush toilet, the absorbent article includes a pulp layer containing a crushed pulp or fibers mainly containing a crushed pulp, and the pulp layer has a water repellent surface layer portion formed by applying a water repellent agent to at least one surface layer portion. 1. An absorbent article comprising a pulp layer containing a crushed pulp or fibers mainly containing a crushed pulp , whereinthe pulp layer has a water repellent surface layer portion formed by applying a water repellent agent to at least one surface layer portion.2. The absorbent article according to claim 1 , further comprising a water-disintegrable sheet layer joined to the pulp layer.3. The absorbent article according to claim 1 , wherein the water repellent agent is a silicon-based compound or a fluorine-based compound.4. The absorbent article according to claim 1 , wherein the water repellent surface layer portion has a non-uniform water repellent strength by the water repellent agent.5. The absorbent article according to claim 1 , further comprising a plurality of the pulp layers.6. The absorbent article according to claim 5 , wherein the plurality of pulp layers is formed such that the amount of the water repellent agent applied increases from a pulp layer located on a skin surface side toward a pulp layer located on a non-skin surface side when the absorbent article is attached to a human body.7. The absorbent article according to claim 1 , having an embossed shape on a skin surface when the absorbent article is attached to a human body.8. The absorbent article according to claim 1 , wherein the water repellent surface layer portion is located on a non-skin surface side when the absorbent article is attached to a human body.9. The absorbent article according to ...

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Номер записи: 77
25-02-2021 дата публикации

SOLUBLE METALLOGELS INCLUDING ANTIMICROBIAL SILVER METALLOGELS

Номер: US20210051948A1
Автор: Ackerson Christopher J., Armstrong James, Compel William, Morrison Keith
Принадлежит:

A product includes a metallogel material having metal ions dispersed in an assembly having an organic compound. A method includes combining a metal salt, an organic compound precursor, and a glyme for forming a metallogel material having metal ions dispersed in an assembly having an organic compound. 120.-. (canceled)21. A method , comprising:contacting a coinage metal-thiolate metallogel material with an object for disinfecting the object and/or providing adhesion thereto, the metallogel material comprising metal ions having antimicrobial properties.22. The method of claim 21 , wherein the contacting includes spraying the metallogel material onto the object.23. The method of claim 21 , comprising altering a viscosity of the metallogel material by adding a solvent thereto prior to the contacting.24. The method of claim 21 , wherein the object is an electrode.25. The method of claim 21 , wherein the object has a biofilm infection.26. The method of claim 21 , wherein the metallogel material is powdered and packaged in a package claim 21 , and comprising adding a solvent to the powdered metallogel material for forming an antimicrobial topical treatment claim 21 , wherein the contacting includes applying the antimicrobial topical treatment to a wound.27. The method of claim 21 , wherein the object is a bandage.28. The method of claim 21 , wherein contacting the metallogel material with the object includes mixing the metallogel material with water for disinfecting the water.29. An antimicrobial product claim 21 , comprising:a coinage metal-thiolate metallogel material comprising coinage metal ions having antimicrobial properties; anda solvent combined with the metallogel material to form an antimicrobial mixture.30. The antimicrobial product of claim 29 , wherein the antimicrobial mixture is in the form of a spray.31. The antimicrobial product of claim 29 , wherein the antimicrobial mixture is in the form of a paste.32. The antimicrobial product of claim 29 , wherein the ...

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Номер записи: 78
14-02-2019 дата публикации

Method For Preparing Superabsorbent Polymer And Superabsorbent Polymer

Номер: US20190046682A1
Автор: CHOI Yong Seok, KIM Jinseok, KIM Na Kyung, Kim Young Sam, Lee Jong-chan, Lim Jong Doo
Принадлежит:

The present invention relates to a method for preparing superabsorbent polymer that has antibacterial activity, in which the basic properties of superabsorbent polymer are maintained or improved, and may exhibits excellent bacterial proliferation inhibition effect, and superabsorbent polymer prepared thereby. The preparation method of superabsorbent polymer comprises the steps of: forming base polymer powder using hydogel polymer comprising crosslinked polymer, and then, surface crosslinking the base polymer powder using a surface crosslinking solution comprising a surface crosslinking agent and cuprous oxide, wherein the cuprous oxide is included in the content of 0.001 to 2.5 parts by weight, based on 100 parts by weight of the base polymer powder. 1. A method for preparing superabsorbent polymer comprising the steps ofconducting crosslinking polymerization of water soluble ethylenically unsaturated monomers having acid groups of which at least a part are neutralized, in the presence of an internal crosslinking agent, to form hydrogel polymer;drying, grinding and sieving the hydrogel polymer to form base polymer powder; andsurface crosslinking the base polymer powder using a surface crosslinking solution comprising a surface crosslinking agent and cuprous oxide as an antibacterial agent,wherein the cuprous oxide is included in the content of 0.001 to 2.5 parts by weight, based on 100 parts by weight of the base polymer powder.2. The method according to claim 1 , wherein the cuprous oxide is included in the content of 0.1 to 2.5 parts by weight claim 1 , based on 100 parts by weight of the base polymer powder.3. The method according to claim 2 , wherein CRC is 39 to 50 g/g claim 2 , and AUP is 16 to 23 g/g.4. The method according to claim 1 , wherein the cuprous oxide is included in the content of 0.001 to 0.1 parts by weight claim 1 , based on 100 parts by weight of the base polymer powder.5. The method according to claim 4 , wherein CRC is 30 to 50 g/g claim 4 , ...

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Номер записи: 79
25-02-2016 дата публикации

Urine Detection Inductor Suitable For Large-scale Production

Номер: US20160051417A1
Автор: CHIU Joseph
Принадлежит:

A detector for wet diaper is suitable for large-scale production. The detector comprises a nonwoven fabric () and at least two electrodes () which are carbon powder coated on the nonwoven fabric (). The length of the electrodes () is 2-20 mm while the length thereof is more than 3 times than that of the width. The carbon powder is adaptable to the skin of the infants, the old, and the patients. It will not cause allergy or oppression to the skin. Further, the carbon layer possesses the function of filtration and odor adsorption, which is conducive to the hygiene and health of the subjects, such as, the infant, the old and the patients. 2. The detector according to claim 1 , wherein said third electrode is between said first electrode and said second electrode; the distance between said third electrode and said first electrode or said second electrode is smaller than that between said first electrode and said second electrode.3. The detector according to claim 1 , wherein said third electrode is vertical to said first electrode and said second electrode; the distance between said third electrode and said first electrode or said second electrode is greater than that between said first electrode and said second electrode.4. The detector according to claim 1 , wherein the width of said first electrode or second electrode is 2-20 mm; the length of said first electrode or second electrode is more than 3 times greater than the width thereof.5. The detector according to claim 1 , wherein said first electrode and said second electrode are strip in shape.6. The detector according to claim 1 , wherein a first layer of nonwoven fabric is set above said detector; the density of said first layer of nonwoven fabric is lower than that of said nonwoven fabric in which said electrodes reside.8. The detector according to claim 7 , further comprising a third electrode and a fourth electrode claim 7 , wherein said third and fourth electrodes are between said first and second electrodes. ...

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Номер записи: 80
13-02-2020 дата публикации

USE OF ZINC TREATED PRECIPITATED CALCIUM CARBONATE IN HYGIENIC PRODUCTS

Номер: US20200046869A1
Автор: Ohr Steffen, Schrul Christopher
Принадлежит:

The present invention relates to the use of zinc treated precipitated calcium carbonate (PCC), which is obtained by slaking calcium oxide with water to obtain a calcium hydroxide slurry, carbonating the calcium hydroxide slurry, and adding a Zn ion provider before and/or during the carbonation, in hygienic products, to the hygienic products comprising said zinc treated precipitated calcium carbonate as well as to a process for the preparation of such hygienic products. 120-. (canceled)21. A method of making a hygienic product , the method comprising: carbonating the calcium hydroxide slurry, and', {'sup': '2+', 'adding a Znion provider before and/or during the carbonation; and'}], 'forming a zinc-treated precipitated calcium carbonate, the forming comprising slaking calcium oxide with water to obtain a calcium hydroxide slurry,'}applying or adding the zinc-treated precipitated calcium carbonate to a hygienic item, to form the hygienic product.22. The method of claim 21 , comprising applying or adding the zinc-treated precipitated calcium carbonate to a hygienic item to provide a dry coating weight of 0.05 to 15 mg/cm.23. The method of claim 21 , wherein the hygienic item and the hygienic product are chosen from an ab/adsorbent product claim 21 , a deodorant formulation claim 21 , a nonwoven product claim 21 , and a combination thereof.24. The method of claim 23 , wherein the ab/adsorbent product is chosen from a diaper claim 23 , training panties claim 23 , swim pants claim 23 , a feminine hygiene product claim 23 , an incontinence product claim 23 , and a combination thereof.25. The method of claim 23 , wherein the ab/adsorbent product is a diaper.26. The method of claim 23 , wherein the ab/adsorbent product comprises one or several layers chosen from comprising a top sheet layer claim 23 , one or more acquisition/distribution layer(s) (ADLs) claim 23 , a tissue wrap layer claim 23 , an ab/adsorbent core claim 23 , and a back sheet layer.27. The method of claim 26 ...

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Номер записи: 81
22-02-2018 дата публикации

ABSORBENT ARTICLE WITH PHILIC ANHYDROUS LOTION

Номер: US20180050126A1
Автор: Ebert Debora Christine, Ellingson Peter Christopher, Pan Robert Ya-Lin, Warren Raphael
Принадлежит:

A lotion composition is provided. The lotion composition includes a) about 1% to about 90%, by weight, of a rheology structurant; and a b) carrier. 1. A lotion composition comprising:a) about 1% to about 90% of a rheology structurant; andb) a carrier.2. The lotion of further comprising at least one of a body treatment agent and a viscosity modifier.3. The lotion of wherein the carrier comprises petrolatum.5. The lotion of wherein the body treatment agent comprises zinc oxide and the viscosity modifier comprises fumed silica.6. The lotion of claim 1 , wherein the carrier is selected from the group consisting of avocado oil claim 1 , apricot oil claim 1 , apricot kernel oil claim 1 , babassu oil claim 1 , borage oil claim 1 , borage seed oil claim 1 , calendula oil claim 1 , camellia oil claim 1 , canola oil claim 1 , carrot oil claim 1 , cashew nut oil claim 1 , castor oil claim 1 , chamomile oil claim 1 , cherry pit oil claim 1 , chia oil claim 1 , coconut oil claim 1 , cod liver oil claim 1 , corn oil claim 1 , corn germ oil claim 1 , cottonseed oil claim 1 , eucalyptus oil claim 1 , evening primrose oil claim 1 , grape seed oil claim 1 , hazelnut oil claim 1 , jojoba oil claim 1 , juniper oil claim 1 , kernel oil claim 1 , linseed oil claim 1 , macadamia oil claim 1 , meadowfoam seed oil claim 1 , menhaden oil claim 1 , mink oil claim 1 , moringa oil claim 1 , mortierella oil claim 1 , olive oil claim 1 , palm oil claim 1 , palm kernel oil claim 1 , peanut oil claim 1 , peach kernel oil claim 1 , rapeseed oil claim 1 , rose hip oil claim 1 , safflower oil claim 1 , sandlewood oil claim 1 , sesame oil claim 1 , soybean oil claim 1 , sunflower oil claim 1 , sunflower seed oil claim 1 , sweet almond oil claim 1 , tall oil claim 1 , tea tree oil claim 1 , turnip seed oil claim 1 , walnut oil claim 1 , wheat germ oil claim 1 , zadoary oil claim 1 , soya oil claim 1 , turnip seed oil claim 1 , palm oil claim 1 , olive oil claim 1 , sesame oil claim 1 , cocoa butter ...

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Номер записи: 82
22-02-2018 дата публикации

Cellulose Cyanoacrylate and Method of Employment

Номер: US20180051146A1
Автор: Carlisle Richard S.
Принадлежит:

Cellulose cyanoacrylate is employed either to bond two surfaces or to duplicate the shape of a three-dimensional object. The method is carried out by applying a release material to the object to be duplicated, applying a sheet of cellulosic material formed of wood fibers onto the three dimensional object, then saturating the sheet of cellulosic material with a cyanoacrylate glue and permitting the saturated sheet to cure. The resulting product duplicates the shape of the object. Two surfaces may be bonded by placing a sheet of cellulosic material between the two surfaces and applying the cyanoacrylate glue to edges of the sheet until saturated and allowing it to cure. Paper toweling may favorably be employed as the cellulosic material. This material may also be employed in bone or tooth repair. A break or fracture in an article can be repaired by positioning a sheet of cellulosic material over the break, saturating it with cyanoacrylate glue, and holding the saturated sheet in place with a releasable film. Irritating fumes may be suppressed by covering the saturated cellulosic material with a release film. 120-. (canceled)21. (canceled)22. (canceled)23. (canceled)24. A cellulose cyanoacrylate compound , comprising a waterproof composition of matter formed by saturating fibrous cellulosic material selected from the group consisting of cotton and sheets of paper toweling comprising wood fibers , with liquid cyanoacrylate glue.25. compound of wherein the glue is selected from the group consisting of one or more of cyano-methyl claim 24 , cyano-ethyl and cyano-octyl acrylates.26. compound of having properties of high rigidity and high abrasion resistance.27. compound of shaped while curing with pressure applied through a layer of flexible material that is releasable from the cured surface.28. compound of applied as a support system for repair of a bone fracture. An invention is provided for repairing a wide variety of broken items made of plastic, wood or metal and is ...

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Номер записи: 83
26-02-2015 дата публикации

Anti-microbial dressing, an anti-microbial composition and use thereof

Номер: US20150057617A1
Автор: Gianni Pecorari
Принадлежит: Emodial Srl

The invention relates to an antimicrobial dressing, an anti-microbial composition and use thereof. The dressing comprises: chlorhexidine and/or a pharmaceutically acceptable salt thereof in a solid state in a quantity, calculated as an equivalent weight of chlorhexidine digluconate/surface of dressing, comprised between 0.013 and 2 g/m 2 ; and silver and/or a pharmaceutically-acceptable salt in the solid state in a quantity, calculated as an equivalent weight of metallic silver/surface of dressing of greater than or equal to 0.1 g/m 2 . The composition comprises: chlorhexidine and/or a pharmaceutically acceptable salt thereof in a solid state in a relative weight/weight percentage, calculated as an equivalent weight of chlorhexidine digluconate/total weight of the composition, comprised between 0.01% and 0.09%; and silver and/or a pharmaceutically acceptable salt thereof in the solid state in a relative percentage weight/weight comprised between 0.00008% and 0.08%, calculated as an equivalent weight of metallic silver/total weight of the composition; and at least a pharmaceutically-acceptable excipient.

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Номер записи: 84
21-02-2019 дата публикации

ANTI-MICROBIAL ARTICLES AND METHODS OF USING SAME

Номер: US20190054202A1
Автор: Demirgöz Döne, Liu Junkang J., Stepanova Narina, Veeraraghavan Badri, Yu Ta-Hua
Принадлежит: 3M INNOVATIVE PROPERTIES COMPANY

An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate having two opposing major surfaces, wherein one opposing major surface is a nanostructured surface; a metal oxide layer, wherein the nanostructured surface is coated with the metal oxide layer and the metal oxide layer comprises a metal oxide; and a metal layer overlaying the metal oxide layer. 1. An article comprising:an occlusive layer;a substrate having two opposing major surfaces, wherein one opposing major surface is a nanostructured surface;a metal oxide layer, wherein the nanostructured surface is coated with the metal oxide layer and the metal oxide layer comprises a metal oxide; anda metal layer overlaying the metal oxide layer.2. An article comprising:an occlusive layer;a substrate having two opposing major surfaces, wherein one opposing major surface is a nanostructured surface;a metal layer, wherein the nanostructured surface is coated with the metal layer; anda metal oxide layer overlaying the metal layer, wherein the metal oxide layer comprises a metal oxide.3. The article of claim 1 , wherein the metal layer adjourns the metal oxide layer.4. The article of claim 1 , wherein the metal layer is discontinuous or patterned.5. The article of claim 1 , wherein the metal oxide layer is in direct contact with one opposing major surface of the substrate and the metal layer is in direct contact with the other opposing major surface of the substrate.6. The article of claim 1 , wherein the nanostructured surface comprises an anisotropic nanostructure.7. The article of claim 1 , wherein the metal oxide is selected from silver oxide claim 1 , copper oxide claim 1 , gold oxide claim 1 , platinum oxide claim 1 , zinc oxide claim 1 , magnesium oxide claim 1 , titanium oxide claim 1 , chromium oxide and combinations thereof.8. The article of claim 7 , wherein the metal oxide is silver oxide.9. The article of claim 8 , wherein the silver oxide is AgO.10. The article ...

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Номер записи: 85
04-03-2021 дата публикации

DECORATIVE SPLINT OR CAST MATERIAL

Номер: US20210060202A1
Автор: Watson Cristina
Принадлежит: Bella Bling, LLC

A decorative splint material includes a moisture-curable material adapted to be wetted and molded into a splint configuration that conforms to an anatomical body part. The material hardens via a curing process to retain the splint configuration. The splint material includes a plurality of decorative elements integrated with the splint material. The decorative elements are provided on a substrate which is overlaid onto the moisture-curable material, and the substrate is overlaid with a flexible sheet having a plurality of openings which align with the decorative elements. The decorative elements are retained by the sheet of splint material when the sheet is wetted, molded into a splint configuration, and hardened. 117-. (canceled)18. A decorative splint material comprising:a splint material that is moldable over an anatomical body part in a splint configuration and is configured to harden to retain the splint configuration; anda plurality of separate decorative elements integrated with the splint material, the decorative elements to be retained by the splint material when the splint material is being molded over an anatomical body part; whereineach of the plurality of decorative elements includes a decorative upper portion and a lateral portion that extends laterally beyond the decorative upper portion, the lateral portion being overlaid by a material to help secure the decorative element to the splint material.19. A decorative splint material as in claim 18 , wherein the splint material includes one or more layers of fiberglass fabric impregnated with a moisture-curable polyurethane resin.20. A decorative splint material as in claim 19 , wherein the splint material includes one or more areas comprising a thermoplastic material.21. A decorative splint material as in claim 18 , wherein the splint material includes one or more areas comprising a thermoplastic material.22. A decorative splint material as in claim 21 , wherein the thermoplastic material holds the ...

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Номер записи: 86
02-03-2017 дата публикации

NOVEL COMPOSITE MATERIALS COMPRISING A THERMOPLASTIC MATRIX POLYMER AND WOOD PARTICLES

Номер: US20170058120A1
Автор: PÄRSSINEN Antti
Принадлежит: Onbone Oy

The present invention concerns a novel low-temperature thermoplastic wood-biopolymer composite comprised of small wood particles and a polycaprolactone (PCL) homopolymer for use in medical procedures including orthopedic casting or splinting. The material is made from a thermoplastic composite that softens when heated to approximately 60° C., after which it can be formed directly on the patient. The composite then retains its shape as it cools down. The material is composed of epsilon caprolactone homopolymer reinforced with discontinuous short length wood particles. 1. A sports orthosis device comprising:a composite material including:a first component formed by a biodegradable thermoplastic polymer, anda second component formed by a reinforcing material, the second component including granular or plate-like wood particles.2. A sports orthosis device according to claim 1 , wherein the device is a shin pad.3. The sports orthosis device according to claim 1 , wherein the composite material comprises:5 to 99 parts by weight of a thermoplastic polymer component; and1 to 95 parts by weight of the wood particles, the weight of the wood particles being calculated based on the dry weight of said wood particles.4. The sports orthosis device according to claim 3 , wherein the composite material comprises:40 to 99 parts by weight of a thermoplastic polymer component; and1 to 60 parts by weight of the wood particles, the weight of the wood particles being calculated based on the dry weight of said wood particles.5. A foot-supporting device comprising:a composite material including:a first component formed by a biodegradable thermoplastic polymer, anda second component formed by a reinforcing material, the second component including granular or plate-like wood particles.6. A foot-supporting device according to claim 5 , wherein the device is an insole.7. The foot-supporting device according to claim 5 , wherein the composite material comprises:5 to 99 parts by weight of a ...

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Номер записи: 87
28-02-2019 дата публикации

Hygiene Articles and Processes for Making the Same

Номер: US20190060507A1
Автор: TANG Qi, Van Loon Achiel J.M.
Принадлежит:

A hygiene article, including at least one top sheet, at least one absorbent core; and at least one backsheet, is provided. A process for producing the hygiene article is also provided. 2. The hygiene article of claim 1 , wherein the at least one backsheet comprises from 10 wt % to 40 wt % of the first polyethylene polymer.3. The hygiene article of claim 1 , wherein the at least one backsheet comprises from 15 wt % to 25 wt % of the first polyethylene polymer.4. The hygiene article of any one of the preceding claims claim 1 , wherein the first polyethylene polymer has a density from 0.920 g/cmto 0.930 g/cm.5. The hygiene article of any one of the preceding claims claim 1 , wherein the first polyethylene polymer has a melt index (MI) from 0.3 dg/min to 1.0 dg/min.6. The hygiene article of any one of the preceding claims claim 1 , wherein the first polyethylene polymer has a melt index ratio (MIR) from 30 to 55.7. The hygiene article of any one of the preceding claims claim 1 , wherein the first polyethylene polymer has a melt index ratio (MIR) from 35 to 50.8. The hygiene article of any one of the preceding claims claim 1 , wherein the first polyethylene polymer has a melt strength of 0.01 cN to 1.0 cN.9. The hygiene article of any one of the preceding claims claim 1 , wherein the first polyethylene polymer has a melt strength of 0.02 cN to 0.1 cN.10. The hygiene article of any one of the preceding claims claim 1 , wherein the first polyethylene polymer has a g′ branching index from 0.97 to 0.99.11. The hygiene article of any one of - claim 1 , wherein the first polyethylene polymer has a g′ branching index from 0.95 to 0.98.12. The hygiene article of any one of the preceding claims claim 1 , wherein the at least one backsheet comprises from 40 wt % to 10 wt % of a second polyethylene polymer.13. The hygiene article of any one of the preceding claims claim 1 , wherein the at least one backsheet comprises from 30 wt % to 15 wt % of the second polyethylene polymer.14. ...

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Номер записи: 88
10-03-2016 дата публикации

FIBRINOGEN-BASED TISSUE ADHESIVE PATCHES

Номер: US20160067371A1
Автор: Cohen Eran, Cohn Daniel, LAUB Orgad, ZAREK Matthew
Принадлежит: SEALANTIUM MEDICAL LTD

A novel fibrinogen-based tissue adhesive patch is disclosed. The patch comprises a backing made from a non-permeable biocompatible polymer film into which a fibrinogen-based sealant is incorporated. In preferred embodiments of the invention, the fibrinogen-based sealant comprises fibrinogen, thrombin, and CaCl. The polymer backing serves to seal the tissue to which the patch is applied, and the sealant acts only to bind the patch to the affected tissue. The patch does not include any mesh or woven component. Methods of production of the patch are also disclosed. 162.-. (canceled)64. The tissue adhesive patch according to claim 63 , wherein said fibrinogen sealant comprises fibrinogen claim 63 , thrombin claim 63 , and CaCl.65. The tissue adhesive patch according to claim 63 , wherein said fibrinogen sealant comprises fibrinogen but does not comprise thrombin.66. The tissue adhesive patch according to claim 63 , wherein said tissue adhesive patch does not comprise any hemostatic agent in the form of a free powder.67. The tissue adhesive patch according to claim 63 , wherein said biocompatible polymer is characterized by at least one characteristic selected from the group consisting of:said biocompatible polymer is non-permeable; and,wherein said biocompatible polymer is selected from the group consisting of polyethylene glycol-polycaprolactone copolymers; polyethylene glycol-DL-lactide copolymers; and polyethylene glycol-polycaprolactone-DL-lactide copolymers.68. The tissue adhesive patch according to claim 63 , wherein said fibrinogen sealant additionally comprises at least one additive.69. The tissue adhesive patch according to claim 68 , wherein said additive is selected from the group consisting of additives for extending the adhesion half-life of said film claim 68 , pharmaceutically active agents claim 68 , and analgesics.70. A method for producing a fibrinogen-based tissue adhesive patch claim 68 , wherein said method comprises:casting a polymer film from a ...

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Номер записи: 89
27-02-2020 дата публикации

ZINC CHLORIDE HYDROXIDE HAVING EXCELLENT ZINC ION SUSTAINED-RELEASABILITY AND PRODUCTION METHOD THEREFOR

Номер: US20200061109A1
Автор: ECHIZENYA Yuko, NAKATA Yoshimi, UDAGAWA Etsurou, Yamamoto Osamu
Принадлежит:

Provided are: zinc chloride hydroxide that is useful as a pharmaceutical ingredient, has excellent zinc ion sustained-releasbility when used as a pharmaceutical agent, and exhibits excellent stability as a pharmaceutical ingredient; and a production method therefor. Disclosed is zinc chloride hydroxide that can be used as a pharmaceutical ingredient, that has excellent zinc ion sustained-releasability, that includes at least one member selected from the group consisting of zinc chloride, zinc hydroxide, and zinc oxide. 1. (canceled)2. A zinc chloride hydroxide having an excellent zinc ion sustained-release property , which can be used as an active ingredient of a pharmaceutical , comprising zinc chloride hydroxide hydrate , wherein the zinc chloride hydroxide hydrate comprises simonkolleite.3. The zinc chloride hydroxide having an excellent zinc ion sustained-release property according to claim 2 , which can be used as an active ingredient of a pharmaceutical claim 2 , wherein an amount of dissolved Zn ions is from 0.25 to 100 μg/mper unit surface area claim 2 , and pH is not less than 7.0 and less than 8.3 claim 2 , after a dissolution test by stirring method performed on the simonkolleite-containing zinc chloride hydroxide hydrate;{'sup': '2', 'where, in the dissolution test, a BET specific surface area of the simonkolleite-containing zinc chloride hydroxide hydrate is from 10 to 150 m/g, a mass ratio of the simonkolleite-containing zinc chloride hydroxide hydrate to saline is 1:50, and a time for stirring at 37° C. using a rotor at 500 rpm is 3 hours.'}4. The zinc chloride hydroxide having an excellent zinc ion sustained-release property according to claim 3 , which can be used as an active ingredient of a pharmaceutical claim 3 , wherein a structure of ZnCl(OH)·nHO is dominant in an XRD diffraction pattern of the simonkolleite-containing zinc chloride hydroxide hydrate claim 3 , where a axis is from 6.3 to 6.345 and c axis is from 23.4 to 23.7.5. The zinc ...

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Номер записи: 90
08-03-2018 дата публикации

WOUND DRESSING

Номер: US20180064841A1
Автор: Stoecker William Van Dover
Принадлежит:

Embodiments disclosed herein provide compositions, methods, and uses for treating skin wounds, including chronic wounds such as venous ulcers. Certain embodiments provide methods for treating a skin wound, where the entire wound is exposed to zinc, especially in the form of zinc gauze. Certain embodiments provide methods for treating a skin wound, where only a peripheral rim of the wound is exposed to zinc, especially in the form of zinc oxide gauze. Other embodiments provide wound dressings and wound dressing kits, where the dressing and dressing kits include central gauze free of zinc to contact a central drainage zone of the wound and a second zinc gauze to contact a peripheral healing zone of the wound. In certain embodiments, the central gauze is optional. 1. A wound dressing comprising:a central drainage gauze configured to occupy an approximately central area in a wound such that from about 2 mm to about 10 mm of the wound periphery is not covered by the central drainage gauze; anda zinc gauze configured to occupy the exposed wound periphery not covered by the central drainage gauze.2. A wound dressing kit comprising:a central drainage gauze configured to occupy an approximately central area in a wound such that from about 2 mm to about 10 mm of the wound periphery is not covered by the central drainage gauze; anda zinc gauze configured to occupy the exposed wound periphery not covered by the central drainage gauze.3. The wound dressing kit according to claim 2 , further comprising a physiological saline solution.4. The wound dressing kit according to claim 2 , further comprising a retention layer.5. The wound dressing kit according to claim 2 , wherein the zinc gauze is affixed to an adhesive strip.6. A method to dress a wound claim 2 , the method comprising:cutting a central drainage gauze, wherein the cut central drainage gauze leaves an exposed periphery of the wound having a width of about 2 mm to about 10 mm when placed approximately centrally in the ...

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Номер записи: 91
11-03-2021 дата публикации

Wound dressing materials and methods of making thereof

Номер: US20210069022A1
Автор: Martin Coffey, Ramon Verduzco
Принадлежит: Medline Industries LP

Disclosed is a wound dressing material comprising a substrate, about 2.5% to about 8% by weight of a bicarbonate, and a film-forming agent, the film-forming agent serving as a binder for said bicarbonate to said substrate, the film-forming agent and the bicarbonate being present in a ratio of between 1:2 and 2:1 with respect to one another. Also disclosed are a method for preparing a wound dressing material and a method for treating a wound.

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Номер записи: 92
11-03-2021 дата публикации

SILICA FIBER HEMOSTATIC DEVICES AND METHODS

Номер: US20210069373A1
Автор: DELLINGER Mitch
Принадлежит:

Embodiments of the invention include hemostatic compositions, delivery devices, kits, and methods utilizing silica fibers or other silica fiber compositions. The fiber compositions may be formed via electrospinning of a sol gel produced with a silicon alkoxide reagent, such as tetraethyl ortho silicate, alcohol solvent, and an acid catalyst. 1. A method for treating a subject for hemorrhage , the method comprising applying an electrospun silica fiber composition to said hemorrhage in an amount and under conditions sufficient to stop the hemorrhage.2. The method of claim 1 , wherein the silica fiber composition is prepared by electrospinning a sol that is prepared with 70% to 90% tetraethyl orthosilicate (TEOS) by weight claim 1 , 8% to 25% ethanol by weight claim 1 , an acid catalyst claim 1 , and the balance water.3. The method of claim 2 , wherein the sol is transitioned for 2 to 7 days under conditions where humidity is within the range of 40% to 80% claim 2 , and the temperature is within the range of 50 to 90° F.4. The method of claim 3 , wherein the sol is not exposed to heat over 150° F. or heat over 100° F.5. The method of claim 2 , wherein the acid catalyst is HCl.6. The method of claim 1 , wherein the subject is a mammal.7. The method of claim 6 , wherein the subject is a human.82. The method of claim 1 , wherein the hemorrhage is at least a Grade hemorrhage.9. The method of claim 8 , wherein the hemorrhage is a Grade 3 or Grade 4 hemorrhage.10. The method of claim 9 , wherein the hemorrhage is an arterial hemorrhage.11. The method of claim 9 , wherein the hemorrhage is a venous hemorrhage.12. The method of claim 8 , wherein the hemorrhage is bleeding during or after surgery.13. The method of claim 12 , wherein the hemorrhage is an organ bleed.14. The method of claim 8 , wherein the hemorrhage is a primary hemorrhage.15. The method of claim 8 , wherein the hemorrhage is a reactionary hemorrhage.16. The method of claim 8 , wherein the hemorrhage is a ...

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Номер записи: 93
12-03-2015 дата публикации

Antimicrobial Silver Compositions

Номер: US20150072066A1
Автор: Cornell Kenneth A., Gibbins Bruce L., Karandikar Bhalchandra M.
Принадлежит:

The present invention comprises methods and compositions for antimicrobial silver compositions comprising silver nanoparticles. The present invention further comprises compositions for preparing silver nanoparticles comprising at least one stabilizing agent, one or more silver compounds, at least one reducing agent and a solvent. In one aspect, the stabilizing agent comprises a surfactant or a polymer. The polymer may comprise polymers such as polyacrylamides, polyurethanes, and polyamides. In one aspect, the silver compound comprises a salt comprising a silver cation and an anion. The anion may comprise saccharinate derivatives, long chain fatty acids, and alkyl dicarboxylates. The methods of the present invention comprise treating devices with the silver nanoparticle compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices. The present invention further comprises treatment of humans and animals wacr6ith the antimicrobial devices described herein. 115-. (canceled)16. A method of treating a surface with silver nanoparticles , comprising , a) contacting a surface with a solution comprising silver nanoparticles for a time sufficient for an effective amount of nanoparticles to bind to the surface , and b) rinsing the solution from the surface.17. The method of claim 16 , wherein the contacting and rinsing steps are repeated multiple times to increase the number of nanoparticles adhering to the surface.18. The method of claim 16 , wherein the surface contacted is a medical device claim 16 , polymer claim 16 , a fiber claim 16 , a metal claim 16 , glass claim 16 , ceramic claim 16 , fabric or combination thereof.19. The method of claim 16 , further comprising c) contacting the surface with nanoparticles adhered thereto with an aqueous solution of hydrogen peroxide for a sufficient period of time claim 16 , and d) rinsing the hydrogen peroxide solution from the surface.20. The method of ...

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Номер записи: 94
11-03-2021 дата публикации

Photocurable composition for 3d printer for producing patient-customized cast

Номер: US20210070913A1
Автор: Un Seob Sim
Принадлежит: Graphy Inc

The present disclosure relates to a photocurable composition for 3D printing for producing a patient-specific splint or cast. The photocurable composition easily produces a splint or cast conforming to the patient's body shape using 3D printing and makes it possible to adjust the immobilizing force of the splint or cast. In addition, the present disclosure provides a patient-specific splint or cast using a photocurable composition for 3D printing, which may produce a splint or cast, which may provide a necessary degree of compression by adjusting the immobilizing force thereof and is attachable and detectable as needed.

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Номер записи: 95
17-03-2016 дата публикации

ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THEIR PRODUCTION

Номер: US20160074436A1
Автор: "OFLAHERTY Vincent", MCCAY Paul
Принадлежит:

This invention relates to a method for preparing compositions for preventing or treating microbial infections, compositions suitable for use in such treatments and methods for treatment or prevention of infections. One such composition finds particular use in treating mastitis in ruminants. The composition is administered into the udder of an animal as a highly effective treatment for mastitis, or as a prophylactic therapy, by means of an intra-mammary infusion. The milk produced by the animal, during treatment using the composition and method of the invention, is free of residues, such as antibiotics, antimicrobial agents or antimicrobial proteins, which could affect its suitability for drinking or in the production of milk products, such as cheese or yoghurt. The compositions and methods are also useful in treating and preventing lung infections; and infections in burns and wounds; and other infections caused by biofilms. The compositions may also be used on medical devices to prevent infection. 1. A pharmaceutical composition comprising iodide (I−) and a source of hydrogen peroxide , together with a pharmaceutically effective carrier or diluent.2. The pharmaceutical composition according to claim 1 , where the concentration of hydrogen peroxide is less than 1% based on weight/volume or weight/weight.3. The pharmaceutical composition according to claim 1 , which does not include a peroxidase enzyme.4. The pharmaceutical composition according to comprising a 0.2:1 to 3:1 ratio by weight of iodide to hydrogen peroxide.5. The pharmaceutical composition according to comprising a 0.38:1 to 1.52:1 ratio by weight of iodide to hydrogen peroxide.6. The pharmaceutical composition according to claim 1 , containing 5-5 claim 1 ,000 mg iodide claim 1 , prepared at a ratio of between 0.2:1 and 3:1 by weight of iodide to hydrogen peroxide.7. The pharmaceutical composition according to claim 1 , containing 5-5 claim 1 ,000 mg iodide claim 1 , prepared at a preferable ratio of ...

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Номер записи: 96
17-03-2016 дата публикации

ODOR ADSORBENT

Номер: US20160074550A1
Автор: Loick Christoph, Wattebled Laurent
Принадлежит:

Described is an odor adsorbent, in particular for use in absorptive hygiene articles, comprising: a) peroxomonosulfuric acid and/or salts thereof and also b) zeolite. Also described are water-absorbing polymeric particles wherein the particles are laden with a mixture comprising a) peroxomonosulfuric acid and/or salts thereof and also b) zeolite, and wherein the water-absorbing polymeric particles preferably comprise a crosslinked polymer based on partially neutralized acrylic acid, and more particularly are surface-postcrosslinked. 1. An odor adsorbent , in particular for use in absorptive hygiene articles , comprising:a) peroxomonosulfuric acid and/or salts thereof,b) zeolite.2. Adsorbent according to claim 1 , characterized in that it comprises from 0.0001 to 15 parts by weight of peroxomonosulfuric acid and/or salts thereof claim 1 , and from 0.0005 to 5 parts by weight of zeolite claim 1 , based on the overall amount of zeolite plus peroxomonosulfuric acid and/or salts thereof.3. Adsorbent according to claim 1 , wherein the zeolites have a particle size of 0.1 to 50 μm.4. Adsorbent according to any of claim 1 , wherein it is in an immobilized state on water-absorbing polymeric particles and more particularly is in solid pulverulent form claim 1 , wherein the water-absorbing polymeric particles preferably comprise a crosslinked polymer based on partially neutralized acrylic acid claim 1 , and more particularly are surface-postcrosslinked.5. Adsorbent according to claim 1 , wherein it includes at least 80% by weight of water-absorbing polymeric particles claim 1 , based on the overall mass of zeolite claim 1 , peroxomonosulfuric acid and/or salts thereof and also water-absorbing polymeric particles.6. A water-absorbing polymeric particle claim 1 , wherein the water-absorbing polymeric particle are laden claim 1 , in particular at least partially coated claim 1 , with a mixture comprisinga) peroxomonosulfuric acid and/or salts thereofb) zeolite,wherein the water- ...

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Номер записи: 97
15-03-2018 дата публикации

COLLAGEN-CONTAINING WOUND DRESSING AND METHOD FOR THE PRODUCTION THEREOF

Номер: US20180071427A1
Автор: Bielenstein Oliver, TADIC Drazen
Принадлежит:

The invention relates to a method for producing an implant, which is in particular in the form of a wound dressing. The implant consists of a sheet-like structure made of magnesium, which is embedded in a collagen non-woven fabric. 115-. (canceled)16. A method for producing a geometrically stable bioresorbable wound dressing membrane , the method comprising:covering a sheet-like structure made of magnesium or a magnesium alloy with a collagen-containing preparation; anddrying of the collagen-containing preparation.17. The method for producing the wound dressing membrane of claim 16 , wherein the collagen-containing preparation comprises a collagen-containing suspension.18. The method for producing the wound dressing membrane of claim 17 , wherein the suspension includes a native collagen.19. The method for producing the wound dressing membrane of claim 16 , wherein the sheet-like structure comprises a mesh.20. The method for producing the wound dressing membrane of claim 16 , further comprising applying the sheet-like structure onto a support.21. The method for producing the wound dressing membrane of claim 20 , wherein the support comprises a collagen membrane.22. The method for producing the wound dressing membrane of claim 16 , further comprising adjusting the collagen-containing preparation to a pH value of greater than 5.5 claim 16 , at least prior to the covering the sheet-like structure with the collagen-containing preparation.23. The method for producing the wound dressing membrane of claim 16 , wherein the drying of the collagen-containing preparation is performed by lyophilization.24. The method for producing the implant of claim 21 , wherein the support comprises a lyophilized skin of animal or a human origin collagen.25. A wound dressing comprising:a collagen-containing sheet-like structure; anda sheet-like structure made of magnesium or a magnesium alloy, comprising openings, the sheet-like structure made of the magnesium or the magnesium alloy embedded ...

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Номер записи: 98
19-03-2015 дата публикации

COMPOSITION AND DRESSING FOR WOUND TREATMENT

Номер: US20150079152A1
Автор: Wuollett Michael, Wuollett Susan
Принадлежит:

The invention provides methods and compositions for wound treatment and/or blood clot formation, e.g., arresting the flow of blood from an open wound. The methods and compositions provide for promoting and accelerating wound healing and optionally provide for inhibition of microbial infection and/or a local analgesic effect. 1. A composition for wound healing , comprising:an amount of mullite, wherein the amount is effective to promote blood clot formation.2. The composition of which is in powder form.3. The composition of which is in aerosol form.4. The composition of which is in gel form.5. The composition of which is applied to a support.6. The composition of claim 1 , further comprising a blood clotting agent.7. The composition of claim 6 , wherein the blood clotting agent is fibrin.8. The composition of claim 1 , further comprising a blood vessel constricting agent.9. The composition of claim 8 , wherein the blood vessel constricting agent is aluminum sulfate.10. The composition of claim 9 , wherein the mullite and aluminum sulfate are present in a 1:1 ratio by volume.11. The composition of claim 8 , further comprising a blood clotting agent.12. The composition of claim 11 , wherein the blood clotting agent is fibrin.13. The composition of claim 1 , further comprising a local anesthetic agent.14. The composition of claim 1 , further comprising an antimicrobial agent.15. A method for promoting blood clot formation claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'contacting a wound on the skin of a mammal with the composition of .'}16. A kit comprising one or more containers including the composition of claim 1 , in sterile packaging.17. A hemostatic device comprising:a substrate; andan amount of mullite, wherein the amount is effective to promote blood clot formation.18. The hemostatic device of claim 17 , further comprising a blood vessel constricting agent.19. The hemostatic device of claim 18 , wherein the blood vessel constricting ...

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Номер записи: 99
19-03-2015 дата публикации

WOUND DRESSING CONTAINING POLYSACCHARIDE AND COLLAGEN

Номер: US20150080815A1
Автор: Chakravarthy Debashish, Ford Andrew J.
Принадлежит: Medline industries, Inc.

A wound dressing makes use of a polysaccharide, such as Manuka honey, in combination with collagen in order to suppress the efficacy of matrix metalloproteinases enzymes (“MMPs”) present in chronic wounds. The mixture is applied to an absorbent surface that is designed to absorb the mixed polysaccharide only partially. 1. A dressing for application to a wound comprising:a wound contacting layer for contacting the wound surface, the wound contacting layer comprising:a first polysaccharide; andan MMP suppressing material.2. The dressing of claim 1 , wherein the first polysaccharide is honey.3. The dressing of claim 2 , wherein the MMP suppressing material is collagen.4. The dressing of claim 3 , wherein the collagen is powdered collagen.5. The dressing of claim 2 , wherein the wound contacting layer comprises greater than 90% by weight of honey.6. The dressing of claim 5 , wherein the wound contacting layer comprises less than 10% by weight of collagen.7. The dressing of claim 2 , wherein the wound contact layer comprises between 10% and 45% by weight of honey.8. The dressing of claim 7 , wherein the wound contact layer comprises between 55% and 90% by weight of collagen.9. The dressing of claim 1 , wherein the wound contact layer further comprises a supplemental material.10. The dressing of claim 9 , wherein the wound contact layer comprises less than 50% by weight of honey.11. The dressing of claim 10 , wherein the wound contact layer comprises greater than 50% by weight of the supplemental material.12. A dressing for application to a wound comprising: a first polysaccharide having a first viscosity;', 'a supplemental material; and', 'an MMP suppressing material;, 'a wound contacting layer for contacting the wound surface, the wound contacting layer comprisingwherein the first polysaccharide, the supplemental material and the MMP suppressing material form a mixture in the wound contacting layer having a viscosity that is greater than the viscosity of the first ...

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Номер записи: 100