LIQUID PUMPING CASSETTES AND ASSOCIATED PRESSURE DISTRIBUTION MANIFOLD AND RELATED METHODS

DISPOSABLE CASSETTE CONDITIONING SYSTEM AND METHOD

Rotary valves for dialysis systems

In one aspect, a dialysis fluid cassette includes an inlet fluid line, multiple outlet fluid lines, and a valve including an actuation feature by which the valve can be rotated to fluidly communicate the inlet fluid line with a selected fluid line of the multiple outlet fluid lines.

PERITONEAL DIALYSIS SYSTEMS AND DEVICES

DISPOSABLE COMPONENTS FOR FLUID LINE AUTOCONNECT SYSTEMS AND METHODS

SYSTEMS AND METHODS FOR INCORPORATING PATIENT PRESSURE INTO MEDICAL FLUID DELIVERY

Easily movable blood purification systems

A dialysis system may include a blood circuit, a cassette, a subsystem having a processor, a sensor, and a blood pumping mechanism, a housing in which the subsystem is arranged, a movable support arranged in the housing and configured to hold the sensor and/or the blood pumping mechanism of the subsystem, a cassette holder configured to removably receive the cassette, and a loading system. The loading system may be configured to move the movable support, e.g. by an axial movement, to a first position and to a second position relatively to the housing while the cassette holder is fixedly arranged in the housing. The loading system may have an electric motor controlled by the processor, a drive assembly coupled to the electric motor, and a guiding assembly configured to cooperate with the drive assembly.

PRESSURE SENSORS, INCLUDING PRESSURE SENSORS FOR AUTOMATED PERITONEAL DIALYSIS SYSTEMS, AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS

ALERT ON A DIALYSIS MACHINE

LIQUID PUMPING CASSETTES AND ASSOCIATED PRESSURE DISTRIBUTION MANIFOLD AND RELATED METHODS

A fluid-handling cassette assembly comprising: a middle cassette interposed between a first outer cassette and a second outer cassette; each said cassette comprising: a mid-plate positioned between a first plate and a second plate, said plates having a length, a width and a plate thickness, a first side of the mid-plate opposing the first plate and a second side of the mid-pate opposing the second plate; the first plate spaced apart from the mid-plate defining a width of a first inter-plate space, and the second plate spaced apart from the mid-plate defining a width of a second inter-plate space; an edge of the cassette having a cassette thickness defined by the thickness of each plate plus the width of the first and second inter-plate spaces, and a face of the cassette being defined by the length and width of the first or second plate; a plurality of diaphragm valves or pumps comprising valve or pump actuation chambers connected to actuation channels running parallel to the face of the ...

Peritoneal dialysis system including manifold assembly and peristaltic pump

A peritoneal dialysis (“PD”) system includes a cycler including an actuation surface having a peristaltic pump actuator; a manifold assembly including a rigid manifold having first and second chambers (110a, 110b), the rigid manifold configured and arranged to be abutted against the actuation surface for operation, a peristaltic pump tube (124gh) extending from the first chamber (110a) to the second chamber (110b) of the rigid manifold, a dialysis fluid container line (124b) extending from the first chamber (110a), and a branch line (124c) extending between the dialysis fluid container line (124b) and the second chamber (110b); and a control unit configured to cause the peristaltic pump actuator to actuate the peristaltic pump tube (124gh) to pump dialysis fluid from the branch line (124c) into the second chamber (110b) and from the second chamber (110b) into the first chamber (110a).

DISPOSABLE CASSETTE CONDITIONING SYSTEM AND METHOD

A medical fluid delivery system comprises: (i) a medical fluid delivery machine including a pneumatic manifold having pump and valve actuation areas and a pumping gasket overlaying the pump and valve actuation areas, sources of positive and negative pneumatic pressure, plural pneumatic valves located between the pneumatic sources and the pump and valve actuation areas, and a control unit in operable communication with the plural pneumatic valves; and (ii) a disposable cassette including a fluid pump chamber that aligns with the pump actuation area when the disposable cassette is mated with the pneumatic manifold, the disposable cassette including sheeting overlaying the fluid pump chamber, wherein the control unit is configured to operate the pneumatic valves to perform a conditioning routine that moves the pumping gasket and the cassette sheeting while mated in an attempt to remove small air pockets from between the pumping gasket and the cassette sheeting.

SAFETY MECHANISM FOR A DIALYSIS SYSTEM

A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a safety feature that is used to isolate individual fluid lines attached to a disposable cassette. The PD machine can include an interface for a disposable cassette, a plurality of safety mechanisms, and a processor. A plurality of fluid lines are connected to the disposable cassette, and each safety mechanism corresponds to a particular fluid line in the plurality of fluid lines. The processor is configured to detect a hazard condition, such as a loss of power to the PD machine or leak in the disposable cassette, and activate one or more safety mechanisms to isolate corresponding fluid lines connected to the disposable cassette. In one embodiment, the safety mechanisms are spring-loaded clamping mechanisms configured to compress a distensible tube connected to the fluid line. In another embodiment, the safety mechanisms include relay solenoids and/or check valves.

PERITONEAL DIALYSIS SYSTEM INCLUDING MANIFOLD ASSEMBLY AND PERISTALTIC PUMP

Fluid Preparation and Treatment Devices Methods and Systems

Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.

PERITONEAL DIALYSIS SYSTEM INCLUDING PERISTALTIC PUMP

Disposable cartridge and pump track mechanism

Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.

CONDUCTIVITY CONTROL SYSTEMS

Fluid preparation and treatment devices methods and systems

Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.

SYSTEMS AND METHODS FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION INCLUDING MIXING AND HEATING THEREFORE

A peritoneal dialysis system (10a, 10b, 10c, 10d) is described. The system comprises: a cycler (20) including a control unit (22) and a pump actuator under control of the control unit; and a disposable set (40) operable with the cycler. The disposable set includes a pumping cassette (42) having a pump chamber (44) configured to be actuated by the pump actuator, and a mixing container (62) in fluid communication with the pumping cassette (42). The control unit (22) is programmed to promote mixing of at least two fluids by (i) causing the pump actuator to operate the pump chamber (44) to pull the at least two fluids from the mixing container into the pump chamber (44), (ii) thereafter causing the pump actuator to operate the pump chamber (44) to push the at least two fluids from the pump chamber (44) to the mixing container (62), and (iii) repeating (i) and (ii) at least one time.

BLOOD TREATMENT SYSTEMS AND METHODS

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

SYSTEMS AND METHODS FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION USING WATER ACCUMULATOR AND DISPOSABLE SET

A peritoneal dialysis system (10a, 10b, 10c, 10d) is described. The system comprises: a water purifier (110) that includes a water outlet connector (128), a water recirculation connector (204b), and an internal recirculation loop (200) from the water outlet connector to the water recirculation connector; a cycler (20); and a disposable set (40) operable with the cycler. The disposable set includes: a pumping cassette (42) including a water inlet port, a water line (64) in fluid communication with the water inlet port and the water outlet connector (128), the water line including at least one sterile sterilizing grade filter (70), and a recirculation line (202a) having a first end that is in fluid communication with the water line (64) downstream from the at least one sterile sterilizing grade filter (70) and a second end that is in fluid communication the water recirculation connector (204b). The recirculation line (202a) and the internal recirculation loop (200) are configured to absorb ...

PRESERVING SORBENT DEVICES IN DIALYSIS SYSTEMS

PERITONEAL DIALYSIS SYSTEM INCLUDING MANIFOLD ASSEMBLY AND PERISTALTIC PUMP

SYSTEMS AND METHODS FOR INCORPORATING PATIENT PRESSURE INTO MEDICAL FLUID DELIVERY

A medical fluid delivery system (110) is described. The system comprises: a medical fluid handling device (170) including a patient line (116) for being placed in fluid communication with a patient; and a medical fluid delivery machine (120) including a pump actuator (126) for actuating the medical fluid handling device to move medical fluid into or out of the device, a pressure sensor positioned and arranged within the medical fluid handling device and configured to sense pressure of the medical fluid, and a control unit (160) in signal communication with the pressure sensor and control communication with the pump actuator, the control unit programmed to perform a routine during pumping in which the control unit (i) determines when at least one signal reading or a component of the at least one signal reading from the pressure sensor is indicative of a pressure within the patient, and (ii) determines from the at least one pressure signal reading or component reading indicative of the pressure ...

FLUID LINE AUTOCONNECT APPARATUS AND METHODS FOR MEDICAL TREATMENT SYSTEM

Method for trending automated peritoneal dialysis treatments

A method for performing a peritoneal dialysis therapy includes performing a plurality of peritoneal dialysis cycles for a patient and tracking an amount of dialysis fluid provided by at least one dialysis fluid pump during the plurality of peritoneal dialysis cycles. The method also includes determining an amount of ultrafiltrate (“UF”) removed from the patient based on the amount of dialysis fluid provided by the at least one dialysis fluid pump. The method further includes updating a UF trend using previous amounts of UF removed from the patient and the amount of UF removed from the patient during the most recent dialysis treatment and generating an alert if the UF trend changes by more than a preset percentage.

WATER PURIFICATION APPARATUS AND METHODS FOR CLEANING THE WATER PURIFICATION APPARATUS

A water purification apparatus capable of being cleaned at a point of care and methods for cleaning the water purification apparatus at the point of care are disclosed herein. The water purification apparatus and the methods provide an efficient use of a heater for heat disinfection the water purification apparatus. The water purification apparatus and the methods provide heat disinfection by recirculating heated fluid to further heat the fluid. Several different cleaning programs are provided that may be utilized for cleaning different parts of the water purification apparatus.

VALVE ACTUATION SYSTEMS AND RELATED METHODS

센서들을 가지며 복막염을 진단하도록 구성된 복막 투석 시스템

An impedance measurement system is described. The system comprises: an impedance monitor (230) that is configured to sense an impedance of peritoneal dialysis ("PD") fluid residing within a fluid line (50, 55, 56) and a control unit (22) that is electrically coupled to the impedance monitor. The impedance monitor includes a first conductive lead (248a) disposed within a first port (242) along the fluid line, and a second conductive lead (248b) disposed within a second port (246) along the fluid line. The control unit (22) is configured to use the sensed impedance from the impedance monitor to detect white blood cells to form a patient peritonitis determination, and to communicate the peritonitis determination.

FLUID HANDLING SYSTEM

A fluid handling system includes a console configured to connect with a first electrical interface that is configured to connect to a plurality of components of the fluid handling system, the console including a second electrical interface configured to connect with the first electrical interface, a display, and one or more hardware processors. A control system includes the one or more hardware processors and a non-transitory memory storing instructions that, when executed, cause the control system to: detect an electrical signal from a first component of the plurality of components of the fluid handling system responsive to a caretaker performing a first instruction; determine a system state of the fluid handling system based at least in part on the electrical signal from the first component; compare the system state with a predetermined state condition corresponding to said first instruction; and output an indication on the display of the system state.

ROTARY VALVES FOR DIALYSIS SYSTEMS

In one aspect, a dialysis fluid cassette includes an inlet fluid line, multiple outlet fluid lines, and a valve including an actuation feature by which the valve can be rotated to fluidly communicate the inlet fluid line with a selected fluid line of the multiple outlet fluid lines.

METHOD OF HEAT SANITIZATION OF A HAEMODIALYSIS WATER CIRCUIT USING A CALCULATED DOSE

WATER PURIFICATION APPARATUS AND METHODS FOR CLEANING THE WATER PURIFICATION APPARATUS

Disclosed herein is a water purification apparatus capable of being cleaned at a point of care, and methods for cleaning the water purification apparatus at the point of care. The water purification apparatus and the methods provide an efficient use of a heater for heat disinfection the water purification apparatus, e.g. by recirculating heated fluid to further heat the fluid. Several different cleaning programs are provided that may be utilized for cleaning different parts of the water purification apparatus.

A DIALYSIS SYSTEM

Systems and methods for peritoneal dialysis having point of use dialysis fluid preparation including mixing and heating therefore

A peritoneal dialysis system includes a cycler including a pump actuator, a heater and a heating pan operable with the heater, and a disposable set operable with the cycler. The heating pan includes a sidewall forming a slot. The disposable set includes a pumping cassette and a heater/mixing container. The pumping cassette includes a pump chamber configured to be actuated by the pump actuator. Additionally, the heater/mixing container is in fluid communication with the pumping cassette and is sized to be received at the heating pan. The heater/mixing container includes a port configured such that when the port is slid into the slot of the heater pan sidewall, the port is prevented from rotating about an axis transverse to a direction of flow through the port.

Medical treatment system and methods using a plurality of fluid lines

A system including a pumping cassette having a first side including number of valve wells and second side having a fluid bus. Each side may be covered by a flexible membrane. A control surface having a number of valve well control stations actuatable with respect to the flexible membrane covering the first side of the cassette to open and close the valve wells when the cassette is mated against the control surface may be included. A pressure distribution assembly having a positive and negative pressure source and a number of pneumatic valves may be included. A controller configured to selectively actuate the number of pneumatic valves to apply pressure against the valve well control stations in a valve pumping sequence until a volume displaced through the fluid bus of the pumping cassette from a source to a destination is within a range of a target volume may be included.

SYSTEM FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION INCLUDING MIXING AND HEATING THEREFORE

PERITONEAL DIALYSIS CYCLER USING MICROPUMP

DIALYSIS SYSTEM AND METHOD INCLUDING A FLOW PATH INSULATOR

PERSONALIZED RENAL FAILURE CHRONIC CARE SYSTEMS AND METHODS

A personalized chronic care apparatus is disclosed herein. An example apparatus includes a server operating over a network, software stored on the server, and a compliance entry feature configured to receive compliance information related to a patient. The software includes an automated learning method for creating an overall kidney maintenance plan that specifies one or more controllable variables as actions performed by the patient to prevent or reduce complications associated with chronic kidney disease (“CKD”). The automated learning method is configured to perform an evaluation to determine whether a selected controllable variable is to be included in the overall kidney maintenance plan by confirming when (i) a worsening of kidney function is not determined between first evaluation data and second evaluation data over a testing period, and (ii) the compliance information provides a confirmation that the selected controllable variable was modified over the testing period.

LIQUID PUMPING CASSETTES AND ASSOCIATED PRESSURE DISTRIBUTION MANIFOLD AND RELATED METHODS

A fluid-handling cassette assembly comprising: a middle cassette interposed between a first outer cassette and a second outer cassette; each said cassette comprising: a mid-plate positioned between a first plate and a second plate, said plates having a length, a width and a plate thickness, a first side of the mid-plate opposing the first plate and a second side of the mid-pate opposing the second plate; the first plate spaced apart from the mid-plate defining a width of a first inter-plate space, and the second plate spaced apart from the mid-plate defining a width of a second inter-plate space; an edge of the cassette having a cassette thickness defined by the thickness of each plate plus the width of the first and second inter-plate spaces, and a face of the cassette being defined by the length and width of the first or second plate; a plurality of diaphragm valves or pumps comprising valve or pump actuation chambers connected to actuation channels running parallel to the face of the ...

IMPEDANCE SENSOR CONFIGURED TO DIAGNOSE PERITONITIS DURING PERITONEAL DIALYSIS

An impedance measurement system is described. The system comprises: an impedance monitor (230) that is configured to sense an impedance of peritoneal dialysis ("PD") fluid residing within a fluid line (50, 55, 56) and a control unit (22) that is electrically coupled to the impedance monitor. The impedance monitor includes a first conductive lead (248a) disposed within a first port (242) along the fluid line, and a second conductive lead (248b) disposed within a second port (246) along the fluid line. The control unit (22) is configured to use the sensed impedance from the impedance monitor to detect white blood cells to form a patient peritonitis determination, and to communicate the peritonitis determination.

DIALYSATE BAG HEATER TRAY FOR PERITONEAL DIALYSIS SYSTEMS

MEDICAL FLUID CASSETTE LEAK DETECTION METHODS AND DEVICES

DISPOSABLE COMPONENTS FOR FLUID LINE AUTOCONNECT SYSTEMS AND METHODS

A fluid handling cassette for use in a medical infusion system, the cassette comprising: a generally planar body having first and second pump chambers each formed as a depression in a first side of the body, each pump chamber having a first port and a second port connecting the respective pump chamber to a second side of the body; a plurality of valve wells on the first side of the body including first and second groups of valve wells, valve wells in the first group of valve wells each comprising a valve port and an opening connecting a respective valve well to the second side of the body; valve wells in the second group of valve wells each comprising a valve port connecting a respective valve well to the second side of the body, and each fluidly connected to a respective one of a plurality of cassette ports located on a first end of the body; and a first and second fluid flowpath on the second side of the body, each fluid flowpath connected to the first or second port of a respective pump ...

System and method for preparing peritoneal dialysis fluid at the time of use

A peritoneal dialysis system includes first and second concentrate sources in selective fluid communication with a medical fluid pumping cassette, the first and second concentrate sources holding first and second peritoneal dialysis concentrates, respectively; a pump actuator configured to cause the medical fluid pumping cassette to pump the first and second concentrates; and a processor and memory configured to (i) determine a cumulative volume of at least one of the first or second peritoneal dialysis concentrates pumped from the medical fluid pumping cassette by the pump actuator, (ii) compare the cumulative volume to a threshold, and (iii) if the cumulative volume is outside of the threshold, modify a subsequent stroke volume of at least one of the first or second pump chambers actuated by the pump actuator in an attempt to cause an updated cumulative volume for the at least one peritoneal dialysis concentrate to be within the threshold.

Hemodialysis system including a disposable set and a dialysis instrument

A hemodialysis system is disclosed. The hemodialysis system includes a dialyzer, a saline container including saline, and a disposable set comprising a blood pumping tube fluidly connected to a first end of the dialyzer, an arterial line fluidly connected to a first end of the blood pumping tube, a venous line fluidly connected to a second end of the dialyzer, a saline line fluidly connected to the blood pumping tube and the saline container, and a dialyzer line fluidly connected to a second end of the blood pumping tube and a second end of the dialyzer. The hemodialysis system also includes a dialysis instrument comprising an arterial line clamp, a venous line clamp, and a saline valve. The saline rinses blood out of the arterial line when the venous line clamp is closed, the arterial line clamp is opened, and the saline value is opened.

Fluid handling system

A fluid handling system includes a console configured to connect with a first electrical interface that is configured to connect to a plurality of components of the fluid handling system, the console including a second electrical interface configured to connect with the first electrical interface, a display, and one or more hardware processors. A control system includes the one or more hardware processors and a non-transitory memory storing instructions that, when executed, cause the control system to: detect an electrical signal from a first component of the plurality of components of the fluid handling system responsive to a caretaker performing a first instruction; determine a system state of the fluid handling system based at least in part on the electrical signal from the first component; compare the system state with a predetermined state condition corresponding to said first instruction; and output an indication on the display of the system state.

Peritoneal dialysis systems, devices, and methods

A medical treatment system includes a disposable fluid circuit that includes a water inlet and a batch container arranged to hold a mixture, the mixture including water that is received from the water inlet and at least one concentrate. The fluid circuit also includes a drain line for draining fluid from the disposable fluid circuit, and a manifold with a plurality of fluid lines, the manifold connecting the water inlet, the batch container, a source of the at least one concentrate, and the drain line. A source of purified water supplies the purified water to the water inlet and a sensor detects a property of fluid in the disposable fluid circuit. A controller controls flowing of a first fluid followed by displacement by a second fluid causing the first fluid to flow to the sensor.

Medicament preparation and treatment devices, methods, and systems

A medicament preparation system includes a water purification module and a medicament proportioning module that is interoperable with a replaceable fluid circuit. The fluid circuit includes a purified water inlet, a product medicament outlet, and a plurality of pumping tube segments. At least a first concentrate container is connected by at least a portion of the fluid circuit to the product medicament output and a first concentration measurement sensor station is positioned in a flow path. A controller is programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container and the purified water from a signal generated by the first concentration measurement sensor station and to regulate one or both of a first pumping actuator engaged with the first pumping tube segment and a second pumping actuator engaged with the second pumping tube segment, responsively to the concentration of the first concentrate and water.

Measuring fluid flow associated with a dialysis machine

A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a control unit configured to monitor an amount of fluid withdrawn from a heater bag line during a PD treatment. A processor in the control unit is configured to operate a first pump to draw fluid into a first pump chamber and measure a first fluid volume in the first pump chamber. The processor is further configured to operate the first pump and a second pump to transfer fluid from the first pump chamber to a second pump chamber, measure a second fluid volume in the second pump chamber, and determine a measured fluid volume for a single pump cycle based on the first fluid volume and the second fluid volume. The first fluid volume is correlated to the second fluid volume and, therefore, the multiple independent measurements increase an accuracy of the fluid volume measurement.

SMART DIALYSIS BAG DETECTION SYSTEM

A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a safety feature that enables the dialysis machine to automatically identify the connections made by a user in preparation for treatment. A smart connector is disclosed that uses a split RFID device that is operational when a first portion of the connector is mated to a second portion of the connector, and is not operational when the first portion is disconnected from the second portion. In an embodiment, the split RFID device incorporates an RFID chip in the first portion of the connector and an antenna in the second portion of the connector. In an embodiment, the RFID chip can store a tag that encodes information that indicates a formulation or a volume of a dialysis bag connected to the ports of a disposable cassette such that the dialysis machine can automatically discover the configuration of the dialysis setup.

Medical Device Heaters and Methods

A medical device having a heater with at least one heating element which has mains voltage applied to it by a heating control unit. The heating control unit includes a monitoring arrangement and a switching arrangement. The monitoring arrangement can recognize the zero crossings of the mains voltage, and the switching arrangement can switch the at least one heating element on or off in the zero crossing. The heating control unit controls the power of the heating by switching on and off of one or more half cycles of the mains AC voltage.

Medical fluid pumping systems and related devices and methods

This disclosure relates to medical fluid pumping systems and related devices and methods. In some aspects, a medical fluid pumping system includes a medical fluid pumping machine including a piston head that can be linearly displaced and a medical fluid cassette that can be secured to the medical fluid pumping machine. The medical fluid cassette includes a fastening member attached to a region of a flexible membrane overlying a fluid pump chamber, and the piston head is configured to be mechanically connected to the fastening member of the cassette.

Medical functional device, treatment apparatus and method

A medical functional device includes at least one first fluid system for receiving at least one medical fluid, at least one first conveying device for conveying the medical fluid, at least one second fluid system for receiving at least one operating fluid, and at least one second conveying device for operating the at least first conveying device, in which the first conveying device is arranged such as to be actuated by means of the operating fluid. A treatment apparatus and a method are also described.

Blood treatment systems and methods

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid, may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

Dialysis machine with electrical insulation for variable voltage input

A dialysis machine includes: a source of dialysis solution; a pump configured to pump the dialysis solution; a heater configured to heat the dialysis solution; an electrical input receiving power from a remote power source; and a housing supporting the pump, the heater and the electrical input, the housing including an electrical insulation rated for 240 VAC such that the remote power source can be either 110 or 240 VAC.

Medical fluid cassettes and related systems and methods

A medical fluid pumping system that includes a medical fluid pumping machine that includes an actuator and a medical fluid cassette that can be disposed within a cassette enclosure of the medical fluid pumping machine. A member is disposed within a fluid pump chamber of the medical fluid cassette and is magnetically attracted to the actuator such that the member and the actuator can be coupled together when the cassette is disposed within the cassette enclosure.

Systems and methods for treating and estimating progression of chronic kidney disease

Exemplary systems and methods for estimating progression of chronic kidney disease in a patient and applying clinical interventions may include determining historic values of at least one patient parameter that varies as a function of the progression of the chronic kidney disease over time, and computationally estimating a trend corresponding to the historic values. Based on the trend, at least one marker may be automatically provided that identifies a clinical intervention and a time in the future when the clinical intervention is expected to be needed. Based on the at least one marker, clinical preparations may be executed at a time prior to the administration of the intervention in order to improve at least one of a) timeliness of the execution of the intervention and b) effectiveness of the intervention.

Medical treatment system and methods using a plurality of fluid lines

Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of a diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater. Improvements are also disclosed in the application of negative pressure during a drain phase in peritoneal dialysis therapy, and to control the amount of intraperitoneal fluid accumulation during a therapy. Improvements in efficiency are also disclosed in the movement of fluid into and out of a two-pump cassette and heater bag of a peritoneal dialysis cycler, and in the synchronization of the operation of two or more pumps in a peritoneal dialysis cycler or other fluid handling devices using a multi-pump arrangement.

Portable hemodialysis assembly with ammonia sensor

A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate, and pressure and fluid flow sensors for measuring the pressure and fluid flow in the dialysate flow path and blood flow path. Preferably, the filter has a vapor membrane for releasing gases including ammonia, but not liquids such as the dialysate. The reused dialysis machine possesses a reservoir for dialysate, an ammonia sensor adjacent to the vapor membrane, a level sensor, a blood leak sensor, a venous blood line pressure sensor, a venous blood line bubble detector, pump motors, and a processor connected to the motors and sensors for controlling and monitoring hemodialysis treatment.

Portable hemodialysis machine and disposable cartridge with blood leak sensor

A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate. The reused dialysis machine possesses a reservoir for dialysate, various sensors including a blood leak sensor assembly, and a processor connected to the various sensors for controlling and monitoring hemodialysis treatment. The blood leak sensor assembly includes a light source for emitting light through the dialysate flow path and a light sensor for receiving light having passed through the dialysate flow path. The processor is connected to the light source for determining whether blood has leaked from the blood flow path into the dialysate flow path. Preferably, the light source emits light having two peak wavelengths.

Fluid handling system

A system for coupling a motor assembly to a control console is disclosed. The motor assembly is configured to drive a percutaneous heart pump. The system includes a motor coupling comprising a first end having an electrical connection and a fluid connection coupled to a respective electrical conduit and fluid conduit of the motor assembly, and a second end spaced apart from the first end including an interface coupling coupled to the electrical conduit and fluid conduit. An interface member is configured to be removably coupled to the control console, the interface member comprising a corresponding connector coupleable to the interface coupling of the second end of the motor coupling, wherein the interface member is configured to provide a sterile attachment of the fluid conduit to the control console.

Medical treatment system and methods using a plurality of fluid lines

A medical treatment system, such as peritoneal dialysis system, may include control and other features to enhance patient comfort and ease of use. For example, a peritoneal dialysis system may include a control system that can adjust the volume of fluid infused into the peritoneal cavity to prevent the intraperitoneal fluid volume from exceeding a pre-determined amount. The control system can adjust by adding one or more therapy cycles, allowing for fill volumes during each cycle to be reduced. The control system may continue to allow the fluid to drain from the peritoneal cavity as completely as possible before starting the next therapy cycle. The control system may also adjust the dwell time of fluid within the peritoneal cavity during therapy cycles in order to complete a therapy within a scheduled time period. The cycler may also be configured to have a heater control system that monitors both the temperature of a heating tray and the temperature of a bag of dialysis fluid in order to bring the temperature of the dialysis fluid rapidly to a specified temperature, with minimal temperature overshoot.

Peritoneal dialysis patient line with sterilizing filter and drain bypass

A medical fluid treatment system includes a source of purified water; at least one concentrate for mixing with the water from the source to form a treatment fluid; a disposable set including a pumping portion, a concentrate line in fluid communication with the concentrate source and the pumping portion, and a patient line in fluid communication with the pumping portion, the patient line including a filter having a membrane configured to filter the treatment fluid, the filter configured such that (i) fresh treatment fluid flowing from the pumping portion towards a patient flows through the membrane and (ii) used treatment fluid flowing through the filter from the patient to the pumping portion bypasses the membrane; and a medical fluid delivery machine including a pump actuator operable with the pumping portion of the disposable set.

Medical Treatment System and Methods Using a Plurality of Fluid Lines

Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of a diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater. Improvements are also disclosed in the application of negative pressure during a drain phase in peritoneal dialysis therapy, and to control the amount of intraperitoneal fluid accumulation during a therapy. Improvements in efficiency are also disclosed in the movement of fluid into and out of a two-pump cassette and heater bag of a peritoneal dialysis cycler, and in the synchronization of the operation of two or more pumps in a peritoneal dialysis cycler or other fluid handling devices using a multi-pump arrangement.

Fluid processing apparatus

A machine is provided with a slot to releasably receive and retain a cartridge in which dialysis is effected. The machine is configured for supplying to the cartridge, at a controlled temperature and rate, sterile water for use in haemodialysis and is operable to maintain, in a sterile condition, residual water contained therein after completion of a haemodialysis treatment.

Liquid pumping cassettes and associated pressure distribution manifold and related methods

A fluid-handling cassette comprising a plurality of diaphragm valves and pumps is configured to have its actuation ports located along a thin or narrow edge of the cassette. Actuation channels within the cassette lead from the actuation ports to actuation chambers of the valves and pumps in a space between plates that comprise the cassette. The individual plates have a nominal thickness that is sufficient to provide a rigid ceiling for the actuation channels, but sufficiently thin to minimize the overall thickness of the cassette. The cassette can be plugged into or unplugged from an actuation receptacle or a manifold by its narrow edge. A plurality of such cassettes can be stacked together or spaced apart from each other to form a cassette assembly, providing for a convenient way to install and remove the cassette assembly from its actuation receptacle. The arrangement allows for an improved way of connecting a complex cassette assembly to its associated pressure distribution manifold without the use of a plurality of flexible connecting tubes between the two.

Dialysis device and method of dialysis

A dialysis device is provided including a disposable housing having a flow path along which dialysate received from a patient is subjected to contaminant removal when in operation. The device includes a controller for controlling the operation of the disposable housing and an interface capable of operably coupling the controller and the disposable housing to enable the contaminant removal from the dialysate. The flow path is fluidly sealed from the controller and interface.

Medical fluid cassette leak detection methods and devices

A method is provided for detecting leaks in a disposable medical fluid cassette that includes a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway. The method includes applying a first force to the flexible membrane, measuring a first physical property of a system that includes the medical fluid cassette a medical fluid pumping machine, removing the first force from the flexible membrane, applying a second force to the flexible membrane, measuring a second physical property of the system, and determining whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.

Medical device heaters and methods

A medical device having a heater with at least one heating element which has mains voltage applied to it by a heating control unit. The heating control unit includes a monitoring arrangement and a switching arrangement. The monitoring arrangement can recognize the zero crossings of the mains voltage, and the switching arrangement can switch the at least one heating element on or off in the zero crossing. The heating control unit controls the power of the heating by switching on and off of one or more half cycles of the mains AC voltage.

Medical fluid cassettes and related systems and methods

This disclosure relates to medical fluid cassettes and related systems and methods. In certain aspects, a medical fluid cassette includes a base having a first region and a second region, a first membrane overlying the first region of the base, and a second membrane overlying the second region of the base. The second membrane is configured to rebound away from the base when a force used to press the second membrane toward the base is released.

Peritoneal Dialysis Systems, Devices, and Methods

A method of performing a peritoneal dialysis treatment includes connecting a disposable unit to a source of water, the disposable unit including at least a first container holding a sterile concentrate containing an osmotic agent, a second container holding a sterile concentrate containing electrolytes, an empty sterile mixing container, and a tubing set with a pre-attached peritoneal fill/drain line. The method further includes receiving a prescription command by a controller, indicating at least the fill volume and desired final concentration of the osmotic agent to be used for a current fill cycle under said treatment, and using the controller, pumping a quantity of the concentrated osmotic agent that is at least sufficient to achieve the desired final concentration into the mixing container. The contents of the mixing container are mixed, further diluted or concentrated, and then flowed to a patient.

Device and method for treating a medical fluid and medical cassette

An apparatus for treating a medical fluid is provided which includes a treatment machine having a coupling surface, with a cassette made of a hard part having liquid-conducting passages which are covered by a flexible film being able to be coupled to the coupling surface of the treatment machine. A corresponding medical cassette is also provided. An air-free coupling of the flexible film of the cassette to the treatment machine is ensured in that air can be sucked out areally along a plane between the flexible film and the coupling surface during the coupling process and/or with a coupled cassette. A method for coupling the cassette and a method for checking the leaktightness of the cassette via the vacuum control of the air suction is also provided.

Peritoneal Dialysis Systems, Devices, and Methods

An automated peritoneal dialysis system provides both cycler-assisted peritoneal dialysis treatment. The system includes a fluid preparation and treatment device with concentrate dilution components connected to a source of purified water and medicament concentrate. The treatment device has at least one mixing container connected via a pump and valves to the sources, the valves and the pump mixing and diluting the concentrate to form a medicament. Conductivity sensors are provided for fluid quality measurement, calibration, error trapping, and fluid characterization.

Pressure control gaskets for operating pump cassette membranes

A pump cassette comprising an outer flexible membrane covering flowpaths, valve chambers and pump chambers of the cassette is designed to be actuated by a control gasket on a base unit arranged to move designated valve and pump portions of the cassette membrane. The performance of a cassette valve may improved by optimizing the configuration of the valve control region of the control gasket overlying the cassette valve. This may improve both fluid flow through the valve and reduce the amount of vibratory noise associated with opening the valve. The gasket valve control or actuation region is at least partially bounded by a vacuum channel facing the outside of the gasket so that a constant vacuum can be applied between the gasket valve control or actuation region and the adjacent portion of the cassette membrane. An improved version of the vacuum channel comprises a flexible inner wall (contiguous with the valve control region) so that the inner wall flexes or partially collapses away from the cassette valve seat, while still maintaining patency of the vacuum channel during the application of negative pressure on the gasket valve actuation region to open the cassette valve.

Dialysis Systems, Devices, and Methods

A treatment device system includes a treatment machine for performing a therapy on a patient, the treatment machine including at least one fluid conveyor and a controller, the controller having a first memory, to cause the at least one fluid conveyor to produce a therapeutic fluid by mixing purified water and at least one concentrate. The system also includes and a water purifier in fluid communication with and providing the purified water to the treatment machine. A wired or wireless control line provides two way communication between the controller of the treatment machine and the internal central controller of the water purifier, wherein the controller of the treatment machine transmits data via the control line to the internal central controller of the water purifier for control of the water purifier, the data provided based on at least one of the operator inputs received via the user interface.

Device for extracorporeal blood treatment

The invention relates to a system for treating blood, which includes a single cassette capable of carrying out the various CRRT treatments.

Automated Extracorporeal Blood Treatment Apparatus

The present invention provides an extracorporeal dialysis apparatus which allows the automation of some operations in order to make possible a safe home treatment or to facilitate the treatment process for example the priming and/or the blood return process. Thus, the object is to automatically perform a series of processes from hemodialysis preparation to treatment completion safely, reliably and speedily, and to significantly reduce the labor and supply costs.

Systems and methods for determining functionality of dialysis patients for assessing parameters and timing of palliative and/or hospice care

A method and system for determining a functionality level of dialysis patients for assessing parameters and timing of care. In one embodiment, the method includes extracting patient data from one or databases corresponding to a pool of patients having end stage renal disease (ESRD); using a predictive model with the extracted patient data to generate, for each of the patients in the pool of patients, a respective patient functional status score; identifying a subset of the pool of patients having a respective patient functional status score that is lower than a predetermined threshold value and/or a patient functional status score that is trending downwards; and based on the identified subset of the pool of patients, providing one or more treatment plans, wherein the treatment plans include at least one of (a) commencing one of an interventional treatment plan, or (b) commencing palliative and/or hospice care, or (c) combinations thereof.

Portable hemodialysis machine and disposable cartridge

A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialyzer, and a dialysate flow path and a blood flow path which flow in opposing directions through the dialyzer. The disposable cartridge includes pressure and fluid flow sensors for measuring the pressure and fluid flow in the dialysate flow path and blood flow path. In addition, the disposable cartridge possesses pump actuators (but not pump motors) for pumping dialysate and blood through their respective flow paths. Preferably, the disposable cartridge includes a filter for removing waste products from dialysate.

Method of heat sanitization of a haemodialysis water circuit using a calculated dose

A method of sanitizing liquid for use in a. medical device, the method comprising the steps of providing a medical device defining a water circuit with a volume of liquid, sensing the temperature of the volume of liquid with a sensor, heating the volume of liquid from an initial temperature to exceed a threshold temperature, maintaining the volume of liquid above the threshold temperature, determining a time-temperature value for the volume of liquid periodically once the threshold temperature has been exceeded, calculating a. cumulative time-temperature value and providing an output signal once the cumulative time-temperature value has reached a level indicative of a sanitizing dose. A medical device and a liquid sanitizer are also disclosed.

Medical Fluid Temperature Control

Devices, systems, and methods can be used to deliver temperature-controlled medical fluids to patients. For example, this disclosure provides devices, systems, and methods for controlling the temperature of dialysate delivered to a patient during a peritoneal dialysis treatment.

Systems and methods for incorporating patient pressure into medical fluid delivery

A medical fluid delivery machine includes a pump interface having an actuation area for delivering positive or negative pressure to a medical fluid handling device; a pressure sensor positioned to measure pressure within the actuation area; a valve positioned to selectively vent the actuation area to atmosphere; and a control unit in signal communication with the pressure sensor and control communication with the valve, the control unit performing a sequence during pumping, wherein (i) application of positive pressure or negative pressure to the actuation area is stopped, the valve is switched to vent the actuation area to atmosphere, then switched to close the actuation area to atmosphere, and at least one pressure signal reading is taken via the pressure sensor, and (ii) a determination is made whether positive pressure or negative pressure to the chamber should be resumed based on the at least one pressure signal reading.

Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure

Pumping mechanisms for performing peritoneal dialysis and the like employ a pumping mechanism comprising a diaphragm that operate in response to applied fluid pressure. Flexible tubing is attached to the pumping mechanism for carrying liquid to and from the patient's peritoneal cavity. An actuating station for pumping mechanism receives the pumping mechanism and attached tubing. A pressure transfer element conveys fluid pressure to the diaphragm for moving liquid through the cassette. An occluder element contacts and crimps closed the tubing attached to the cassette. A first reservoir inflates with positive fluid pressure for contacting the pressure transfer element to hold it in operative contact against the diaphragm. A second reservoir inflates with positive fluid pressure for contacting the occluding element to hold it away from crimping contact with the tubing. At least one of the first and second reservoirs also transports fluid pressure to the pressure transfer element for conveyance to the diaphragm.

Automated dialysis system

The present invention provides automated peritoneal dialysis systems, methods of operating the systems and devices for performing same. A typical therapy performed by the present invention begins by draining dialysis solution that is already in the patient's peritoneal cavity. The system pumps fresh dialysate from one of a plurality of supply bags, through an in-line heater to the patient's peritoneal cavity. After a dwell period, the spent dialysate in the cavity is pumped out of the patient to a drain or other disposal means. The system then pumps fresh dialysate from the supply bags to the patient and the procedure is repeated as defined in the therapy protocol. The system can pump a last bag of dialysate to the peritoneal cavity for an extended dwell, such as a daytime dwell.

Cassete de bomba y métodos para uso en sistema de tratamiento médico mediante el uso una pluralidad de lineas de fluido.

Un casete para manejo de fluido como el que se usa con un dispositivo ciclador de APD u otro aparato de infusión puede incluir un cuerpo generalmente plano que tiene al menos una cámara de bomba formada como una depresión en un primer lado del cuerpo y una pluralidad de trayectorias de flujo para fluido que incluye un canal; un puerto de línea al paciente puede disponerse para conexión a una línea al paciente y estar en comunicación de fluido con la al menos una cámara de bomba mediante al menos una trayectoria de flujo, y una membrana opcional puede fijarse al primer lado del cuerpo sobre la al menos una cámara de bomba; en una modalidad, la membrana puede tener una porción de cámara de bomba con una forma no presionada que generalmente se adapta a la depresión de la cámara de bomba en el cuerpo y se dispone para moverse con el movimiento de fluido en el espacio utilizable del cámara de bomba; uno o más separadores pueden proveerse en la cámara de bomba para prevenir que una membrana de la bomba entre en contacto con una pared interior de la cámara de bomba; se pueden posicionar líneas al paciente, de drenado y/o calentador para ocluirse por separado en relación con una o más líneas de solución que se conectan al casete.

Fastening mechanisms for medical fluid pumping systems and related devices and methods

This disclosure relates to medical fluid pumping systems and related devices and methods. In some aspects, a medical fluid pumping system includes a medical fluid pumping machine including a piston head that can be linearly displaced and a medical fluid cassette that can be secured to the medical fluid pumping machine. The medical fluid cassette includes a fastening member attached to a region of a flexible membrane overlying a fluid pump chamber, and the piston head is configured to be mechanically connected to the fastening member of the cassette. According to an embodiment, the piston head has a retractable latch mechanism for connection and disconnection with the fastening member to reduce an amount of force required to be applied to the fastening member by the piston head. This may reducing deformation of the piston head and the fastening member thereby ensuring that a tight fit is maintained during pumping.

Medical fluid cassette leak detection methods and devices

A method is provided for detecting leaks in a disposable medical fluid cassette that includes a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway. The method includes applying a first force to the flexible membrane, measuring a first physical property of a system that includes the medical fluid cassette a medical fluid pumping machine, removing the first force from the flexible membrane, applying a second force to the flexible membrane, measuring a second physical property of the system, and determining whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.

Peritoneal dialysis machine

A peritoneal dialysis machine including: a housing; a mechanically actuated piston head extending from a pump actuator housed by the housing, the mechanically actuated piston head positioned to extend towards and away from a fluid pumping cassette, the fluid pumping cassette coupled operably to the housing such that a flexible membrane of the fluid pumping cassette faces the piston head; a pressure sensor positioned by the housing adjacent to the mechanically actuated piston head so as to sense a pressure of a medical fluid moved by the mechanically actuated piston head within the fluid pumping cassette; and a vacuum chamber formed about the mechanically actuated piston head, the vacuum chamber holding a vacuum that sucks the flexible membrane of the fluid pumping cassette onto the mechanically actuated piston head as the mechanically actuated piston head extends away from the fluid pumping cassette.

Medical fluid pumping systems and related devices and methods

This disclosure relates to medical fluid pumping systems and related devices and methods. In some aspects, a medical fluid pumping system includes a medical fluid pumping machine including a piston head that can be linearly displaced and a medical fluid cassette that can be secured to the medical fluid pumping machine. The medical fluid cassette includes a fastening member attached to a region of a flexible membrane overlying a fluid pump chamber, and the piston head is configured to be mechanically connected to the fastening member of the cassette.

Dialysis system having integrated pneumatic manifold

A dialysis machine valve manifold assembly includes a plurality of pneumatic valves; a plate including a first side and a second side, the plurality of pneumatic valves mounted to the first side of the plate, the second side of the plate defining a plurality of pneumatic flow paths; and a port header mounted removably to the plate, the port header including a plurality of ports configured to connect sealingly to pneumatic tubing, the ports in fluid communication with the pneumatic valves via the pneumatic flow paths defined in the plate.

Medizinisches Gerät mit einer Heizung

Die vorliegende Erfindung zeigt ein medizinisches Gerät mit einer Heizung mit mindestens einem Heizelement, welches von einer Heizungssteuerung mit Netzspannung beaufschlagt wird. Dabei umfasst die Heizungsteuerung eine Überwachungsanordnung und eine Schaltanordnung, wobei die Überwachungsanordnung die Nulldurchgänge der Netzspannung erkennen und die Schaltanordnung das mindestens eine Heizelement im Nulldurchgang ein- oder auszuschalten kann, wobei die Heizungsteuerung die Leistung der Heizung über das Ein- und Ausschalten einer oder mehrerer Halbwellen der Netzwechselspannung ansteuert.

Automated dialysis pumping system

A peritoneal dialysis system includes: (i) a hardware unit, the hardware unit including a pump actuator; (ii) a disposable unit received by the hardware unit, the disposable unit having a moveable membrane operable with the pump actuator, the pump actuator moveable towards and away from the disposable unit; and (iii) the hardware unit and disposable unit configured to hold a negative pressure between the pump actuator and the moveable membrane of the disposable unit, the negative pressure causing the moveable membrane to follow the pump actuator as the actuator is moved away from the disposable unit, the pump actuator and membrane positioned relative to each other such that the membrane moves with the pump actuator as the actuator is moved into the disposable unit.

Dialysis machine with electrical insulation for variable voltage input

A dialysis machine includes: a source of dialysis solution; a pump configured to pump the dialysis solution; a heater configured to heat the dialysis solution; an electrical input receiving power from a remote power source; and a housing supporting the pump, the heater and the electrical input, the housing including an electrical insulation rated for 240 VAC such that the remote power source can be either 110 or 240 VAC.

Peritoneal dialysis machine

A method for operating a dialysis cassette including a flexible membrane that covers a pump chamber includes allowing a source of fluid to fluidly communicate with the pump chamber of the dialysis cassette, filling the pump chamber with the fluid from the source, mechanically extending the flexible membrane into the pump chamber with a piston head to expel the fluid from the pump chamber through a flow path, and directly sensing a pressure of the fluid flowing through the flow path at a location of the dialysis cassette adjacent to the pump chamber and using the sensed pressure to perform a test prior to delivering fluid to a patient.

Dialysis system having inventory management including online dextrose mixing

An automated peritoneal dialysis system and machine configured to perform dextrose mixing are disclosed. An example dialysis machine includes at least one pump, a first dialysate having a first dextrose level placed in fluid communication with the at least one pump, and a second dialysate having a second dextrose level placed in fluid communication with the at least one pump. The example dialysis machine also includes first and second valves placed between the first and second dialysates and the at least one pump. The example dialysis machine further includes a logic implementer programmed to operate the at least one pump and the first and second valves to mix the first and second dialysates so as to form a third dextrose level.

Medical fluid cassettes and related systems and methods

A medical fluid delivery cassette configured for use with a medical fluid pumping system and related systems and methods. The medical fluid delivery cassette includes a base and a membrane that together define a fluid pump chamber. The medical fluid delivery cassette further includes a member configured to apply an outward force to an inner surface of the membrane.

Medical fluid cassette leak detection methods and devices

A method is provided for detecting leaks in a disposable medical fluid cassette that includes a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway. The method includes applying a first force to the flexible membrane, measuring a first physical property of a system that includes the medical fluid cassette a medical fluid pumping machine, removing the first force from the flexible membrane, applying a second force to the flexible membrane, measuring a second physical property of the system, and determining whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.

Disposable cassette, delivery set and system for peritoneal dialysis

A disposable cassette for use in peritoneal dialysis includes a pair of diaphragms, tube connectors, pump chambers, channel paths, and valves. A disposable dialysate delivery set for use in peritoneal dialysis includes a cassette, multiple liquid flow paths, multiple valves, tube connectors, and disposable flexible plastic tubes to convey dialysate to and from the patient and other locations within the system. A system for performing peritoneal dialysis includes disposable supply containers of fresh dialysate, a cassette including a pump, a disposable heater container, and conduits for carrying fresh dialysate and carrying heated dialysate.

Peritoneal dialysis machine with dual voltage heater circuit and method of operation

A portable peritoneal dialysis system having a dual voltage heating system that automatically reconfigures the heating circuit depending upon detection of either 110 VAC or 220 VAC to deliver the same wattage for heating PD solution before delivery to the patient, thus facilitating use of the same machine in the United States and Europe.

Medical fluid cassettes and related systems

The invention relates to an apparatus for the treatment of a medical liquid comprising a liquid treatment machine and a cassette insertable therein substantially made of a rigid base body of the cassette with fitted chambers and passages and a foil covering them.

Dialysis systems and related methods

A dialysis machine that includes a valve member having a deformable area configured to deform outwardly away when pressurized fluid is introduced into the valve member. The valve member is configured so that, when a dialysis fluid cassette is disposed in a cassette compartment of the dialysis machine and pressurized fluid is introduced into the valve member, the deformable area obstructs a fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough.

Portable persistaltic pump for peritoneal dialysis

A pump assembly for ambulatory peritoneal dialysis transfer procedures includes a portable power supply geared to drive a high-volume peristaltic pump. A cassette of the pump comprises an encasement; tubing including an inner portion positioned within the encasement, a patient-side portion for connection to an indwelling peritoneal dialysis catheter and an opposing portion connectable to a system for containment and communication of a peritoneal dialysis solution which may be one single-compartment bag assembly; a safety valve for selectively occluding and permitting the communication of the solution through the inner portion; and a filter preferably interposed along the patient-side portion which filters air and particles from peritoneal dialysate that is flowing toward a patient and which allows peritoneal dialysate to flow substantially freely and unfiltered away from the patient.

Peritoneal dialysis systems, devices, and methods

An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid circuit with a pressure sensor at either end and methods and devices for using the pressure signals. Other features and embodiments are disclosed.

Fluid preparation and treatment devices methods and systems

Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.

Peritoneal dialysis systems employing a liquid distribution and pumping cassette that emulates gravity flow

Peritoneal dialysis systems apply fluid pressure to move liquid. The systems can emulate either a fixed head height condition or different head height conditions, independent of the actual head height differential between the patient's peritoneal cavity and the external liquid source or destination. The systems can also switch between low-relative pressure flow mode when considerations of patient comfort and safety predominate and a high-relative pressure flow mode when considerations of processing speed predominate.

Peritoneal dialysis system with variable pressure drive

A variable pressure drive peritoneal dialysis system has a pneumatic pressure system for purging and controlling a flow of dialysate through a disposable dialysate cassette of a disposable dialysate delivery set. The pneumatic pressure system has a variable-opening flow proportional valve for supplying air at selected profiled pressure or vacuum to a pneumatic interface. The disposable dialysate cassette has a diaphragm pump actuable by the profiled air pressure or vacuum to move dialysate to and from a patient via the disposable dialysate delivery set at a desired profiled dialysate pressure.

Peritoneal dialysis systems, devices, and methods

An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid circuit with a pressure sensor at either end and methods and devices for using the pressure signals. Other features and embodiments are disclosed.

Peritoneal dialysis systems, devices, and methods

A disposable fluid circuit used in a medical device that performs peritoneal dialysis includes a peritoneal dialysis tubing set that has a connection tube with a connector for a peritoneal catheter at a distal end and a connector configured to connect to a peritoneal cycler at a proximal end. The circuit also includes a pressure pod at the distal end, the pressure pod being of the type that has a flow chamber for carrying a liquid and an air chamber separated from the flow chamber by a diaphragm and an air port in fluid communication with the air chamber. The flow chamber is connected in-line with a lumen of the connection tube and a length of tubing runs from the air-port along the length of the connection tube with a connector at the proximal end configured to connect to a pressure transducer.

Portable dialysis machine with improved reservoir heating system

The specification discloses a portable dialysis machine having a detachable controller unit and base unit with an improved reservoir heating system. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a reservoir with an internal pan and external pan, separated by a space that holds a heating element. The heating element is electrically coupled to electrical contacts attached to the external surface of the external pan.

歧管膜片

本说明书公开了一种具有可拆卸的控制器单元和基部单元的便携式透析机。控制器单元包括：门，其具有内部面；具有面板的外壳，其中外壳和面板限定配置成接收门的内部面的凹陷区域；以及歧管接收器，其被固定地附接到面板。歧管包括膜片，其适于尽量减小透析机销之间的死空间并且提高响应性。基部单元具有：平面表面，其用于接收流体容器；秤，其与平面表面集成；以及加热器，其与平面表面热连通。所公开的便携式透析系统的实施方案具有改进的结构的和功能的特征，包括改进的模块性、易用性以及安全性特征。

Empaques de control de presión para operación de membranas de casete de bomba.

Un casete de bomba que comprende una membrana externa flexible cubriendo las trayectorias de flujo, cámaras de válvula y cámaras de bomba del casete están diseñadas para accionarse por un empaque de control sobre una unidad base dispuesta para mover la válvula designada y porciones de bomba de la membrana de casete; el desempeño de una válvula de casete puede mejorarse optimizando la configuración de la región de control de válvula del empaque de control que yace encima de la válvula de casete; esto puede mejorar el flujo de fluido a través de la válvula y reducir la cantidad de ruido vibratorio asociado con la abertura de la válvula; el control de válvula de empaque o región de accionamiento está unido al menos parcialmente por un canal de vacío que se orienta hacia el lado externo del empaque de tal manera que puede aplicarse un vacío constante entre el control de válvula de empaque o región de accionamiento y la porción adyacente de la membrana de casete; una versión mejorada el canal de vacío comprende una pared interna flexible (contigua con la región de control de válvula) de tal manera que la pared interna se flexiona o colapsa parcialmente lejos del asiento de válvula de casete, mientras aún mantiene permeabilidad del canal de vacío durante la aplicación de presión negativa sobre la región de accionamiento de válvula de empaque para abrir la válvula de casete.

User interface and monitoring functions for automated peritoneal dialysis systems

Systems for performing peritoneal dialysis having an improved user interface functions and monitoring capabilities. In one respect, the systems discriminate between alarm conditions that require user intervention to correct and alarm conditions that reflect conditions that are anomalies but typically correct themselves with minimum or no user intervention. In another respect, the systems identify occluded liquid flow paths and discriminate whether the flow path is associated with a liquid source or a liquid destination.

Peritoneal dialysis systems and methods employing pneumatic pressure and temperature-corrected liquid volume measurements

Peritoneal dialysis systems and methods move liquid using a pump chamber that is operated in response to pneumatic pressure variations applied by a pump actuator. The systems and methods periodically measure air pressures in the actuator and an associated reference air chamber and derive from these a measurement of liquid volume moved through the pump chamber. The systems and methods minimize derivation errors by compensating for temperature differences among the pump chamber; the pump actuator; and the reference chamber.

User interface for automated peritoneal dialysis systems

Systems for performing peritoneal dialysis allow the user to chose from an array of peritoneal dialysis modalities and adjust one or more individual therapy parameters within a selected modality. Still, the systems assure that the selected modality and therapy parameters satisfy preselected composite therapy criteria.

Electrofluidic standard module and custom circuit board assembly

A miniature electrofluidic module is disclosed, for receiving one or more fluids and for receiving an electrical connection. In accordance with one aspect of the invention, the module includes a substantially flat fluidic manifold layer for fluid distribution, a substantially flat electrical layer including an electrical circuit, and a substantially flat device layer including micromachined devices. The devices may include electrically actuated valves for modulating the flow of fluids. In another aspect of the invention, an electrofluidic module is combined with an electrofluidic circuit board. In a further aspect, an electrofluidic system such as a dialysate handling system is disclosed, including a fluidic fixture and an electrofluidic assembly incorporating electrofluidic devices. In a still further aspect of the invention, a method is disclosed for interfacing micromachined devices to electrical and fluidic interfaces on a fixture, including packaging the devices into a module and providing electrical and fluidic interfaces between the module and the fixture.

Dialysis machine having auto-connection system with roller occluder

A medical fluid or dialysis system includes an auto-connection mechanism that connects connectors from the supply bags to dialysis cassette ports or cassette supply lines. The system provides for multiple, e.g., four, supply bags, which can be connected to a manifold of the auto-connection mechanism. Tip protecting caps that protect the supply line ends and cassette ports or cassette supply line ends are made to be compatible with the auto-connection mechanism. The auto-connection mechanism removes all the caps and connects the supply lines to the cassette. At least one roller occluder is provided that occludes the supply tubing prior to the tip protecting caps being removed. The roller occludes prevent medical dialysis fluid from spilling out of the supply lines between the time that the caps are removed and connection to the cassette is made.

腹膜透析システム

Dialysis system having automated effluent sampling and peritoneal equilibration test

A dialysis system includes at least one dialysis fluid pump actuator, a disposable cassette including at least one pump chamber operable with the at least one pump actuator, the disposable cassette further including a plurality of fluid ports configured to be connected fluidly to a plurality of fluid containers, and a processor programmed to cause the at least one pump actuator to operate the at least one pumping chamber to selectively move effluent dialysis fluid to a drain container or to a sample container.

Capacitance fluid volume measurement

A fluid volumetric pumping system has a fluid pump and capacitor plates disposed around a pump chamber of the fluid pump. The capacitance between the capacitor plates changes as the volume of fluid in the pump chamber changes. An electrical circuit measures a change in the capacitance between the plates and outputs a signal indicative of the volume of fluid in the pump chamber. The pump having the capacitance sensor of the present invention fluidly connects to a patient. In an embodiment, a peritoneal dialysis system provides dialysate to the patient via the pump, and the capacitance sensor measures the volume of dialysate supplied to and drained from a peritoneal cavity of the patient.

Device for treating a medical liquid

The invention relates to an apparatus for the treatment of a medical liquid comprising a liquid treatment machine and a cassette insertable therein substantially made of a rigid base body of the cassette with fitted chambers and passages and a foil covering them. In accordance with the invention, actuators and sensors are arranged in the liquid treatment machine for the operation of the apparatus with the inserted cassette such that cassettes are insertable in different integration shapes.

Dialysis systems having spiraling fluid air separation chambers

A dialysis fluid cassette includes a rigid portion defining at least one valve chamber, the rigid portion further defining an air separation chamber, the air separation chamber when in an operating position including an inner surface, a fluid inlet and a fluid outlet and configured to cause a dialysis fluid to spiral around the inner surface toward the fluid outlet, such that air is removed from the dialysis fluid.

Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure

Pumping mechanisms for performing peritoneal dialysis and the like employ a pumping mechanism comprising a diaphragm that operate in response to applied fluid pressure. Flexible tubing is attached to the pumping mechanism for carrying liquid to and from the patient's peritoneal cavity. An actuating station for pumping mechanism receives the pumping mechanism and attached tubing. A pressure transfer element conveys fluid pressure to the diaphragm for moving liquid through the cassette. An occluder element contacts and crimps closed the tubing attached to the cassette. A first reservoir inflates with positive fluid pressure for contacting the pressure transfer element to hold it in operative contact against the diaphragm. A second reservoir inflates with positive fluid pressure for contacting the occluding element to hold it away from crimping contact with the tubing. At least one of the first and second reservoirs also transports fluid pressure to the pressure transfer element for conveyance to the diaphragm.

Peritoneal dialysis methods that emulate gravity flow

Peritoneal dialysis systems and methods apply fluid pressure to move liquid. The systems and methods can emulate either a fixed head height condition or different head height conditions, independent of the actual head height differential between the patient's peritoneal cavity and the external liquid source or destination. The systems and methods can also switch between low-relative pressure flow mode when considerations of patient comfort and safety predominate and a high-relative pressure flow mode when considerations of processing speed predominate.

Device for treating a medical liquid

An apparatus for the treatment of a medical liquid has a liquid treatment machine and a cassette that is insertable in the machine. The cassette has a rigid base body with fitted chambers and passages and a foil that covers the chambers and passages. Actuators and sensors are arranged in the liquid treatment machine for the operation of the apparatus with the inserted cassette such that cassettes are insertable in different integration shapes.

Vorrichtung und Verfahren zur Behandlung einer medizinischen Flüssigkeit und medizinische Kassette

Die vorliegende Erfindung betrifft eine Vorrichtung zur Behandlung einer medizinischen Flüssigkeit, welche eine Behandlungsmaschine mit einer Ankoppelfläche umfasst, wobei eine Kassette aus einem Hartteil mit flüssigkeitsführenden Kanälen, welche von einer flexiblen Folie abgedeckt sind, an die Ankoppelfläche der Behandlungsmaschine ankoppelbar ist. Weiterhin betrifft die vorliegende Erfindung eine entsprechende medizinische Kassette. Erfindungsgemäß wird eine luftfreie Ankopplung der flexiblen Folie der Kassette an die Behandlungsmaschine dabei dadurch sichergestellt, dass während des Ankoppelvorgangs und/oder bei angekoppelter Kassette Luft flächig entlang einer Ebene zwischen der flexiblen Folie und der Ankoppelfläche abgesaugt werden kann. Ebenso umfasst die Erfindung ein Verfahren zur Ankopplung der Kassette und ein Verfahren zur Überprüfung der Dichtigkeit der Kassette über die Unterdruckregelung der Luftabsaugung.

Dialysis system including heparin injection

A dialysis system includes a dialysis instrument including a blood pump actuator, a dialyzer, a heparin pump, and a disposable cassette including a blood pumping portion operable with the blood pump actuator of the dialysis instrument, the blood pumping portion including an inlet and an outlet, the inlet of the blood pumping portion of the disposable cassette positioned and arranged to receive blood from an arterial line of an extracorporeal circuit, the outlet of the blood pumping portion of the disposable cassette positioned and arranged to deliver the blood to the dialyzer and to receive heparin from the heparin pump.

Noise-reducing dialysis systems and methods of reducing noise in dialysis systems

A dialysis system includes at least one pneumatic valve, a pneumatic pump in fluid communication with the pneumatic valve, a pneumatic line communicating with an inlet and an outlet of the pneumatic pump, a flow restrictor placed in the pneumatic line, and a logic implementer. The logic implementer is programmed to operate the pneumatic valve to either (i) communicate the pneumatic outlet with the pneumatic inlet of the pneumatic pump through the flow restrictor and the pneumatic line, or (ii) communicate the outlet of the pneumatic pump with a component of the dialysis system.

Pressure manifold system for dialysis

A medical fluid pneumatic manifold system includes a plurality of pump and valve chambers for controlling a flow of medical fluid, a header including a plurality of pneumatic passageways, each passageway in pneumatic communication with one of the pump or valve chambers, a plurality of electrically actuated pneumatic valves, and a plate defining a plurality of pneumatic apertures, wherein the header and the plurality of electrically actuated pneumatic valves are separately attached to the plate, such that each pneumatic aperture in the plate is placed in pneumatic communication with one of the plurality of pneumatic passageways of the header and one of the electrically actuated pneumatic valves.

腹膜透析システム

患者に流体投与をするためのシステムに関し、液体ポンプ１と、液体が液体分配システム２からポンプ１に流れることができ、またその逆に流れることができるように、ポンプ１に接続された液体分配システム２と、液体分配システム２とポンプ１とを介して患者４に液体を供給するための液体供給手段３と、液体分配システム２を患者４に接続するようにされた患者導管５とを備え、液体分配システム２が２つの基幹チャンバ７、８を備え、第１の基幹チャンバ７が、バルブ手段９を有する液体供給ポートと、バルブ手段１０を有する患者ポートと、ポンプ入口２６とを含み、第２の基幹チャンバ８が、バルブ手段を有する患者ポート１８又は加熱器ポート１６と、ポンプ出口２７とを含み、システムが、さらに、液体供給ポート９が開いているときに第１の基幹チャンバ７の患者ポート１０を閉じるように配置され、またその逆が行われる制御手段を備えることを特徴とする。

用于流体处理卡盒的弹开压片

本发明提供一种与具有包括多个流体流动端口的阀门站的流体处理卡盒一起使用的压片。所述压片具有大致柔性层和关联所述层的偏压构件。所述压片附接至所述卡盒，以便所述偏压构件被接收在所述阀门站中。所述卡盒可与流体处理系统一起使用，所述流体处理系统具有包括活塞的阀门致动器，所述活塞在使用期间与所述卡盒对准。在伸展位置中，所述活塞将所述压片压靠在所述端口上，以便防止流体流过所述阀门站。当所述活塞从所述伸展位置移动至缩回位置时，就允许所述压片暴露所述端口，由此允许流体流过所述阀门站。在所述活塞移动至所述缩回位置时，所述偏压构件帮助所述压片从所述端口移开。

Система для подведения жидкости к пациенту

ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß (19) RU (11) 2006 104 658 (13) A (51) ÌÏÊ A61M 1/28 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÇÀßÂÊÀ ÍÀ ÈÇÎÁÐÅÒÅÍÈÅ (21), (22) Çà âêà: 2006104658/14, 02.08.2004 (71) Çà âèòåëü(è): ÄÅÁÈÎÒÅÕ Ñ.À. (CH) (30) Êîíâåíöèîííûé ïðèîðèòåò: 31.07.2003 CH PCT/CH03/00528 (43) Äàòà ïóáëèêàöèè çà âêè: 10.09.2007 Áþë. ¹ 25 (87) Ïóáëèêàöè PCT: WO 2005/009512 (03.02.2005) Àäðåñ äë ïåðåïèñêè: 191186, Ñàíêò-Ïåòåðáóðã, à/ 230, "ÀÐÑÏÀÒÅÍÒ", ïàò.ïîâ. Â.Ì.Ðûáàêîâó, ðåã. ¹ 90 R U (57) Ôîðìóëà èçîáðåòåíè 1. Ñèñòåìà äë ïîäâåäåíè æèäêîñòè ê ïàöèåíòó, ñîäåðæàùà åäèíñòâåííûé æèäêîñòíîé íàñîñ (1), ñèñòåìó (2) ðàñïðåäåëåíè æèäêîñòè, ñîåäèíåííóþ ñ óêàçàííûì íàñîñîì (1) ñ îáåñïå÷åíèåì âîçìîæíîñòè äë æèäêîñòè òå÷ü îò ñèñòåìû (2) ðàñïðåäåëåíè æèäêîñòè ê íàñîñó (1) ÷åðåç âõîäíóþ ëèíèþ (56) íàñîñà, è â ïðîòèâîïîëîæíîì íàïðàâëåíèè ÷åðåç âûõîäíóþ ëèíèþ (57) íàñîñà, ïèòàþùóþ åìêîñòü (3) äë æèäêîñòè, ïîäâîäèìîé ê ïàöèåíòó (4) ÷åðåç óêàçàííûå ñèñòåìó (2) ðàñïðåäåëåíè æèäêîñòè è íàñîñ (1), ëèíèþ (5) ê ïàöèåíòó, îáåñïå÷èâàþùóþ âîçìîæíîñòü ïîäêëþ÷åíè ñèñòåìû (2) ðàñïðåäåëåíè æèäêîñòè ê ïàöèåíòó (4), îòëè÷àþùà ñ òåì, ÷òî æèäêîñòíîé íàñîñ (1) âë åòñ íàñîñîì îäíîíàïðàâëåííîãî äåéñòâè , à ñèñòåìà (2) ðàñïðåäåëåíè æèäêîñòè ñîäåðæèò ñðåäñòâà ïåðåêëþ÷åíè , îáåñïå÷èâàþùèå âîçìîæíîñòü ïîäñîåäèíåíè âõîäíîé ëèíèè (56) íàñîñà ê ïèòàþùåé åìêîñòè (3) èëè ê ëèíèè (5) ê ïàöèåíòó. 2. Ñèñòåìà ïî ï.1, îòëè÷àþùà ñ òåì, ÷òî äîïîëíèòåëüíî ñîäåðæèò ñëèâíóþ ëèíèþ (25), ïðè ýòîì ñðåäñòâà ïåðåêëþ÷åíè âûïîëíåíû ñ âîçìîæíîñòüþ ïîäñîåäèíåíè âûõîäíîé ëèíèè (57) íàñîñà ê ñëèâíîé ëèíèè (25) èëè ê ëèíèè (5) ê ïàöèåíòó. 3. Ñèñòåìà ïî ï.1, îòëè÷àþùà ñ òåì, ÷òî æèäêîñòíîé íàñîñ ïðåäñòàâë åò ñîáîé ïåðèñòàëüòè÷åñêèé èëè ðîòàöèîííûé íàñîñ. 4. Ñèñòåìà ïî ï.1, îòëè÷àþùà ñ òåì, ÷òî ñèñòåìà (2) ðàñïðåäåëåíè æèäêîñòè ñîäåðæèò äâå ïðîñòðàíñòâåííî ðàçäåëåííûå ðàñïðåäåëèòåëüíûå êàìåðû (7, 8), ïðè ýòîì ïåðâà ðàñïðåäåëèòåëüíà êàìåðà (7) ñîäåðæèò, ïî ìåíüøåé ìåðå, ïîðò (9) ïîäà÷è ...

用于进行流体施用的系统

一种用于对患者进行流体施用的系统，包括：液体泵(1)；液体分配系统(2)，该系统连接到所述泵(1)上，其方式为液体可从液体分配系统(2)流动到泵(1)上而且反之亦然；液体供应装置(3)，用作经由所述液体分配系统(2)及所述泵(1)把液体供应给患者(4)；患者管线(5)，该患者管线用于把所述液体分配系统(2)连接到患者(4)上；该系统的特征在于，所述泵(1)是单向的，同时所述液体分配系统(2)包括切换装置，该装置设计成可选择地把泵进入管线(56)与供应装置(3)或者与患者管线(5)连接。

用于流体处理卡盒的弹开压片

本发明提供一种与具有包括多个流体流动端口的阀门站的流体处理卡盒一起使用的压片。所述压片具有大致柔性层和关联所述层的偏压构件。所述压片附接至所述卡盒，以便所述偏压构件被接收在所述阀门站中。所述卡盒可与流体处理系统一起使用，所述流体处理系统具有包括活塞的阀门致动器，所述活塞在使用期间与所述卡盒对准。在伸展位置中，所述活塞将所述压片压靠在所述端口上，以便防止流体流过所述阀门站。当所述活塞从所述伸展位置移动至缩回位置时，就允许所述压片暴露所述端口，由此允许流体流过所述阀门站。在所述活塞移动至所述缩回位置时，所述偏压构件帮助所述压片从所述端口移开。

透析机

本发明涉及一种透析机，所述透析机提升了流量平衡。特别地，本发明利用多个传感器(37、39)监测进入和离开病人身体的血压，并使透析液溶液的压力适于供给至透析机，以补偿流体流动路径中的顺应性。结果，通过透析治疗维持了较好的流量平衡，能够更统一地去除血液中的废物。

便携式血液透析机和一次性药筒

提供了一种便携式的血液透析系统，其包括一次性药筒和重复使用的透析机。所述一次性药筒包括透析器，和透析液流动路径和沿相反方向流过透析器的血液流动路径。所述一次性药筒包括用于从透析液除去废物的过滤器和用于测量透析液流动路径和血液流动路径中的压力和流体流速的压力和流体流量传感器。另外，所述一次性药筒拥有泵致动器(而不是泵用马达)以用于泵送透析液和血液通过其相应流动路径。所述重复使用的透析机拥有用于透析液的储罐、液位传感器、血液渗漏传感器、氨气传感器、静脉血管线压力传感器、静脉血管线气泡检测器、泵用马达和连接至电动机与传感器以用于控制和监控血液透析治疗的处理器。

测量与透析机器相关联的流体流量

一种透析机器(例如，腹膜透析(PD)机)，其可以包括被配置成能够监测在PD治疗期间从加热器袋管线抽取的流体的量的控制单元。所述控制单元中的处理器配置成能够操作第一泵以将流体吸入第一泵室中并测量所述第一泵室中的第一流体体积。所述处理器还配置成能够操作所述第一泵和第二泵以将流体从所述第一泵室转移到第二泵室，测量所述第二泵室中的第二流体体积，以及基于所述第一流体体积和所述第二流体体积确定用于单个泵循环的测量的流体体积。所述第一流体体积与所述第二流体体积相关，因此，多个独立测量增加了流体体积测量的准确性。

Система для проведения перитонеального диализа

ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß (19) RU (11) 2006 104 656 (13) A (51) ÌÏÊ A61M 1/28 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÇÀßÂÊÀ ÍÀ ÈÇÎÁÐÅÒÅÍÈÅ (21), (22) Çà âêà: 2006104656/14, 02.08.2004 (71) Çà âèòåëü(è): ÄÅÁÈÎÒÅÕ Ñ.À. (CH) (30) Êîíâåíöèîííûé ïðèîðèòåò: 31.07.2003 CH PCT/CH03/00527 26.01.2004 CH PCT/CH2004/000040 (85) Äàòà ïåðåâîäà çà âêè PCT íà íàöèîíàëüíóþ ôàçó: 28.02.2006 (87) Ïóáëèêàöè PCT: WO 2005/009511 (03.02.2005) Àäðåñ äë ïåðåïèñêè: 191186, Ñàíêò-Ïåòåðáóðã, à/ 230, "ÀÐÑÏÀÒÅÍÒ", ïàò.ïîâ. Â.Ì.Ðûáàêîâó, ðåã. ¹ 90 R U (57) Ôîðìóëà èçîáðåòåíè 1. Ñèñòåìà äë ïîäâåäåíè æèäêîñòè ê ïàöèåíòó, ñîäåðæàùà æèäêîñòíîé íàñîñ (1), ñèñòåìó (2) ðàñïðåäåëåíè æèäêîñòè, ñîåäèíåííóþ ñ óêàçàííûì íàñîñîì (1) ñ îáåñïå÷åíèåì âîçìîæíîñòè äë æèäêîñòè òå÷ü îò ñèñòåìû (2) ðàñïðåäåëåíè æèäêîñòè ê íàñîñó (1) è íàîáîðîò, ïèòàþùóþ åìêîñòü (3) äë æèäêîñòè, ïîäâîäèìîé ê ïàöèåíòó (4) ÷åðåç óêàçàííûå ñèñòåìó (2) ðàñïðåäåëåíè æèäêîñòè è íàñîñ (1), ëèíèþ (5) ê ïàöèåíòó, îáåñïå÷èâàþùóþ âîçìîæíîñòü ïîäêëþ÷åíè ñèñòåìû (2) ðàñïðåäåëåíè æèäêîñòè ê ïàöèåíòó (4), îòëè÷àþùà ñ òåì, ÷òî ñèñòåìà (2) ðàñïðåäåëåíè æèäêîñòè ñîäåðæèò äâå ïðîñòðàíñòâåííî ðàçäåëåííûå ðàñïðåäåëèòåëüíûå êàìåðû (7, 8), ïðè ýòîì ïåðâà ðàñïðåäåëèòåëüíà êàìåðà (7) ñîäåðæèò, ïî ìåíüøåé ìåðå, ïîðò (9) ïîäà÷è æèäêîñòè, ñíàáæåííûé êëàïàíîì, îäèí ïîðò (10) ïîäêëþ÷åíè ïàöèåíòà, ñíàáæåííûé êëàïàíîì, è îäèí âûõîäíîé ïîðò (26) ïîäêëþ÷åíè ê íàñîñó, âòîðà ðàñïðåäåëèòåëüíà êàìåðà (8) ñîäåðæèò, ïî ìåíüøåé ìåðå, îäèí ïîðò (18) ïîäêëþ÷åíè ïàöèåíòà èëè ïîðò (16) ïîäêëþ÷åíè ïàöèåíòà ê ïîäîãðåâàòåëþ, ñíàáæåííûé êëàïàíîì, è îäèí âõîäíîé ïîðò (27) ïîäêëþ÷åíè ê íàñîñó, óêàçàííà ñèñòåìà äîïîëíèòåëüíî ñîäåðæèò ñðåäñòâà óïðàâëåíè , îáåñïå÷èâàþùèå ïåðåêðûòèå ïîðòà (10) ïîäêëþ÷åíè ïàöèåíòà â ïåðâîé ðàñïðåäåëèòåëüíîé êàìåðå (7), êîãäà ïîðò (9) ïîäà÷è æèäêîñòè îòêðûò, è íàîáîðîò. 2. Ñèñòåìà ïî ï.1, îòëè÷àþùà ñ òåì, ÷òî âòîðà ðàñïðåäåëèòåëüíà êàìåðà (8) Ñòðàíèöà: 1 RU A 2 0 0 6 1 0 4 6 5 6 A (54) ÑÈÑÒÅÌÀ ÄËß ...

医用流体温度控制

多种装置、系统和方法可用于向患者输送温度受控的医疗流体。例如，本公开提供了用于在腹膜透析治疗期间控制输送给患者的透析液的温度的装置、系统和方法。

起动外科手术盒的系统和方法

在小切口外科手术中，并且尤其是在眼外科手术中，要将小探针插入手术部位中以切割、去除组织，或以其它方式对组织进行操纵。在这些外科手术过程中，通常使用输注系统将流体输注到眼睛中，并且使用抽吸系统从外科手术部位抽吸输注流体和组织。所述输注系统和所述抽吸系统必须在外科手术之前起动。气体可变得被俘获在所述输注系统和所述抽吸系统内，这会导致某些问题。在现有系统中，起动所述外科手术盒的系统和方法未能将所俘获气体从这些系统去除。因此，仍然需要一种改进的起动外科手术盒的系统和方法。

用于腹膜透析机的数据通信系统

一种便携腹膜透析设备(10)，其具有USB接口，用于使用USB快闪驱动器上传和下载患者的文件和记录，并用于在机器本身的显示器上播放经由USB快闪驱动器传送的PD机的培训视频。

Device and method for treating a medical fluid and medical cassette

本发明涉及处理医用液体的装置，该装置包括具有接合面的处理机，由硬质件构成的盒与该处理机的接合面接合，该硬质件具有被软膜覆盖的多个导流通道。本发明还涉及相应的医用盒。根据本发明，为了确保盒软膜不含空气地被接合到处理机上，在接合过程中和/或在盒已接合到处理机时，空气沿软膜和接合面之间的平面被抽吸走。本发明还涉及用于将盒进行接合的方法，以及通过空气抽吸的负压控制来检验盒密封性的方法。

Pump cassette

一种流体处理盒(24)，例如可以与一个APD循环仪装置或者其它输液设备一起使用，该盒包括大体上扁平的盒体，该盒体具有在其第一侧形成为凹陷部的至少一个泵腔(181)，以及用于流体的、包含通道的多条流动路径。患者管线端口被设置连接到患者管线(34)，并且与所述至少一个泵腔经由至少一条流动路径流体连通，可选用的膜(15)可以被附在所述盒体的第一侧，并处于所述至少一个泵腔之上。在一个实施例中，所述的膜可以具有凹陷形状的泵腔部分(151)，其未拉伸时的形状大体上与所述盒体中的泵腔凹陷部的形状一致，并被设置为可以运动的，以使所述泵腔中的可用空间中的流体运动。在所述的泵腔中具有一个或多个间隔元件(50)，防止泵膜与所述泵腔的内壁接触。患者管线、引流管线(28)和/或加热器袋管线(26)可以被放置成，与可连接到所述盒的一个或多个溶液管线(30)分开封闭。

For the system and method for multi-functional volume fluid control

用于控制受试者与受控相容流路之间的流体运动和流体体积的系统和方法。所述受控相容流路具有选择性地对进出所述受控相容流路的流体进行计量的至少一泵。体外流路与受控相容流路穿过半透膜流体连通，其中所述体外流路具有第一终端和第二终端。

Piston assembly including leak detection in a dialysis machine

本申请公开了一种透析系统以及用于操作透析机器(例如，腹膜透析机器)进行透析治疗的方法。透析系统可以包括用于将透析液从透析液源转移到患者的透析机器。透析液可以从透析液源流过可定位在透析机器内的盒子或盒(例如一次性盒子或盒)。透析机器包括用于将流体(例如，透析液)从盒泵送到患者的活塞。在各种实施例中，在使用期间，活塞被布置和配置成接触、压缩限定盒中的一个或多个流体室的膜等。在一个实施例中，活塞包括用于检测活塞和膜之间的界面处的泄漏的传感器。传感器可以是电容传感器。

Method for preparing a treatment machine and treatment machine

本发明涉及一种用于准备用于处理医用流体的治疗机的方法，所述治疗机包括具有执行件的耦联面，其中由硬质部分组成的盒子可耦联在所述治疗机的所述耦联面上，其中该硬质部分具有由柔韧的薄膜覆盖的导流通道，使得所述执行件能够通过将所述柔韧的薄膜向下压入所述盒内来控制在所述导流通道内的流体流动。在此，在安装所述治疗机后并且在处理开始前，将所述治疗机转到待机模式，在所述待机模式中所述执行件交替运动，以便减轻所述柔韧的薄膜的负荷。通过在处理开始前的根据本发明的待机模式，第一次可能的是，所述治疗机的耗时的安装在时间上完全地脱离治疗本身。此外，本发明包括具有用于实施根据本发明的方法的控制装置的相应的治疗机。

Peritoneal dialysis system with variable pressure drive

(57)【要約】 可変圧力駆動腹膜透析システム（１０）は、使い捨て透析液送達セット（２１）の使い捨て透析液カセット（２３）を通る透析液の流れをパージおよび制御する空気圧システム（１６）を有している。空気圧システム（１６）は、選択されプロファイルを与えられた圧力あるいは真空で空気を空気インタフェース（１８）に供給する可変開口流量配分バルブを有している。使い捨て透析液カセット（２３）は、プロファイルを与えられた空気圧あるいは真空によって作動可能であり、それによってプロファイルを与えられた所望の透析液圧で使い捨て可能透析液送達セット（２１）を介して患者（２８）におよび患者から透析液を移動させるダイアフラムポンプ（Ｐ１、Ｐ２）を有する。

Dialysis fluid measurement systems using conductive contacts

A dialysis system instrument includes a dialysis instrument, a disposable pumping and valving cassette apparatus operable with pumping and valving actuators of the dialysis instrument, the disposable cassette including an electronic cell and electronics associated with the electronic cell, the electronics configured to determine an electrical property of a solution flowing through the electronic cell of the disposable apparatus.

Dialysis system having supply container autoconnection

A dialysis system includes a dialysis instrument including at least one pump actuator; a disposable cassette operable with the at least one pump actuator, a plurality of supply lines connected to the disposable cassette, each supply line including a supply line connector and a supply line tip protector; a plurality of dialysis fluid containers, the dialysis fluid containers each including a solution line having a solution line connector and a solution line tip protector; and an auto-connection mechanism including a solution line connector holder, a supply line connector holder, one of the holders fixed, the other of the holders moveable, and a moveable tip protector remover.

Portable blood dialysis machine and disposable cassette with flow-sensint unit

提供一种便携式血液透析系统，包括一次性盒和重复使用的透析机器。一次性盒包括透析液流动路径和血液流动路径，二者沿相反方向流动通过透析器。一次性盒还包括用于从透析液移除废物的过滤器和用于测量透析液流动路径中透析液的流动的一个或多个流动传感器。优选的流动传感器包括透析液流动路径中的可旋转辐条轮，其通过透析液的流动旋转。辐条轮包括一个或多个磁体，其随辐条轮的旋转而旋转。流动传感器还包括重复使用的透析机器中的磁场传感器，其连接至处理器，用于监测辐条轮的旋转以确定透析液流动路径中流体的流动。