09-01-2020 дата публикации
Номер: US20200009355A1
Принадлежит:
Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms. 1. A method for treating a disease comprising hypertension , diabetes , end-stage renal disease , or obesity , the method comprising:inserting a balloon delivery catheter into a body lumen, comprising inserting the balloon delivery catheter into a treatment site in a main renal artery branch, an extra-renal artery branch, a hepatic artery, a hepatic celiac artery, a hepatic artery branch, a right hepatic artery, a left hepatic artery, a common hepatic artery, a proper hepatic artery, a hepatic celiac artery, a celiac artery, a splenic artery, a gastric artery, a right gastric artery, a left gastric artery, a gastroduodenal artery, or an esophageal branch artery;inflating the balloon delivery catheter at the treatment site;infusing a formulation from the inflated balloon delivery catheter to a wall of the body lumen adjacent to nerves or nerve endings at the treatment site, wherein at least one ingredient of the formulation is chosen from ethanol and acetic acid, wherein an amount of the formulation delivered is effective to injure or damage the nerves or nerve endings to relieve symptoms of the treated disease;deflating the balloon delivery catheter; andwithdrawing the balloon delivery catheter from the body lumen.2. The method of claim 1 , wherein ...
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