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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 8613. Отображено 100.
05-01-2012 дата публикации

Physiological Demand Responsive Control System

Номер: US20120004497A1
Автор: Peter Joseph Ayre
Принадлежит: Thoratec LLC

A demand responsive physiological control system for use with a rotary blood pump; said system including a pump controller which is capable of controlling pump speed of said pump; said system further including a physiological controller, and wherein said physiological controller is adapted to analyze input data relating to physiological condition of a user of said pump; and wherein said physiological controller determines appropriate pumping speed and sends a speed control signal to said pump controller to adjust pump speed; said system further including a physiological state detector which provides said input data indicative of at least one physiological state of said user, in use, to said physiological controller.

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16-02-2012 дата публикации

Devices and methods for respiratory variation monitoring by measurement of respiratory volumes, motion and variability

Номер: US20120041279A1
Принадлежит: Respiratory Motion Inc

This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.

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01-03-2012 дата публикации

Head-mounted display with biological state detection

Номер: US20120050044A1
Принадлежит: Individual

Control of a head-mounted display includes providing a head-mounted display, the head-mounted display includes a switchable viewing area that is switched between a transparent viewing state and an information viewing state. The transparent viewing state is transparent with respect to the viewing area and enables a user of the head-mounted display to view the scene outside the head-mounted display in the user's line of sight. The information viewing state is opaque with respect to the viewing area and displays information in the switchable viewing area visible to a user of the head-mounted display. A user-state detector provides an external stimulus notification in response to a detected change in the biological state of the user and causes the viewing state to automatically switch in response to the external stimulus notification.

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08-03-2012 дата публикации

Apparatus and method for medication delivery using single input-single output (siso) model predictive control

Номер: US20120059351A1
Автор: Pernell E. T. Nordh
Принадлежит: Honeywell International Inc

A method includes receiving measurements from a sensor associated with a patient at a portable medication delivery device. The method also includes controlling delivery of medication to the patient at the portable medication delivery device using a single input, single output (SISO) model predictive control technique. The SISO model predictive control technique includes predicting a characteristic of the patient using the measurements and a model associated with the patient. The SISO model predictive control technique also includes determining whether the characteristic of the patient is predicted to fall outside of a desired range. In addition, the SISO model predictive control technique includes, if the characteristic of the patient is predicted to fall outside of the desired range, determining an amount of medication to deliver to the patient and delivering the determined amount of medication to the patient.

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29-03-2012 дата публикации

Blood Flow Monitoring

Номер: US20120078069A1
Автор: Richard J. Melker

The present invention relates to a method of utilizing photoplethysmography obtained from a central site and a non-central site to detect a low blood flow or low blood volume condition. Also disclosed are apparatuses and systems designed to acquire and process physiological information based on photoplethysmograpy signal information from dual sites.

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03-05-2012 дата публикации

Device and Methods for Applying Therapeutic Protocols to Organs of the Cardiopulmonary System

Номер: US20120103337A1
Автор: Yuval Avni
Принадлежит: RESPINOVA Ltd

The invention is a device for the introduction of a fluid into a human's airway. The air so introduced has a carefully modulated envelope of pressure vs. time, this envelope generally consisting of sequences of pressurized air packets of controlled frequency and pressures. The device produces these packets by means of pressurized air occluded by a shutter action which “chops” and interrupts the fluid stream. The vibrations induced by the device within human organs have been shown to have beneficial effects on various bodily systems, such as increase in heart rate variability, increase in absorbed oxygen, decrease in absorbed CO2, and the like.

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10-05-2012 дата публикации

Automated Therapy System and Method

Номер: US20120116487A1
Принадлежит: Velomedix Inc

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

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07-06-2012 дата публикации

Device, system and method for meal detection for interfacing with and controlling auxiliary devices associated therewith

Номер: US20120143021A1
Автор: Ron Nagar
Принадлежит: Insuline Medical Ltd

The present invention relates to a device, system and method for detecting meal event in a subject and in particular to such a device, system and method for communicating and controlling auxiliary devices and/or systems associated therewith.

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14-06-2012 дата публикации

Acoustic access disconnection systems and methods

Номер: US20120150091A1

An access disconnection system includes a blood treatment machine including a housing, an access site detection housing separate from the blood treatment machine housing, a transmitter positioned in the access site housing and configured to transmit an ultrasound wave into a blood stream of a patient, a receiver positioned in the access site housing and configured to receive a reflection of the ultrasound wave from the blood stream of the patient; and electronic circuitry in communication with the transmitter and the receiver. The electronic circuitry is supported by the access site detection housing, and the transmitter is configured to send a wireless disconnection output to the blood treatment machine. The disconnection output is indicative of a change in the reflected ultrasound wave received by the receiver sufficient to expect that an access disconnection of one of the arterial line and the venous line has occurred.

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21-06-2012 дата публикации

Process for the automatic control of a respirator

Номер: US20120152249A1
Принадлежит: Draëger Medical GmbH

A process for the automatic control of a respirator with a changeover between phases of respiration (inspiration and expiration), by a control unit checking a breathing activity signal for a threshold criterion. If the threshold criterion is met, a changeover is made and the control unit controls the fan of the respirator such that a pneumatic respiration variable (airway pressure, flow) is brought from an actual value to a preset target value for the new phase of respiration. The control unit further divides the change in the respiration variable, from the actual value to the target value, into a plurality of partial steps and checks the current breathing activity signal for the threshold criterion after each partial step. If this threshold criterion is no longer met, the state of operation of the respirator returns to the state before the last changeover, and otherwise, continues with the next partial step.

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02-08-2012 дата публикации

Method and apparatus for machine error detection by combining multiple sensor inputs

Номер: US20120194335A1
Принадлежит: Nxstage Medical Inc

One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Extracorporeal blood treatment systems draw blood at such a high rate that a loss of integrity in the blood circuit can be serious. There are a number of mechanisms for detecting and preventing leaks, but none is perfect. This tends to limit the use of such equipment in unsupervised settings, such as the home will be limited. Some leak detection schemes can be made sensitive enough to detect the barest of leaks, but when this is done, they result in too many false positives. The invention combines information from multiple inputs to enhance sensitivity in leak detection and reduce the problem of false positives.

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30-08-2012 дата публикации

Use of Multiple Spontaneous Breath Types To Promote Patient Ventilator Synchrony

Номер: US20120216811A1
Автор: Gardner Kimm, Peter Doyle
Принадлежит: Nellcor Puritan Bennett LLC

The present disclosure combines the advantages of a hybrid mode of ventilation with an automatic determination of an appropriate spontaneous breath type in response to one or more patient based criteria. Specifically, when the ventilator is delivering a spontaneous breath type, a determination may be made as to whether predetermined ventilatory criteria have been met. Based on the determination the ventilator may deliver one of any number of spontaneous breath types.

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20-09-2012 дата публикации

ECG Artifact Reduction System

Номер: US20120238884A1
Принадлежит: JOHNS HOPKINS UNIVERSITY

An ECG signal processing system which removes the CPR-induced artifact from measured ECG signals obtained during the administration of CPR.

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27-09-2012 дата публикации

Method for delivering gene and cell therapy to a tumor or targeted site using an implanted metronomic biofeedback pump

Номер: US20120245565A1
Принадлежит: Pharmaco Kinesis Corp

A method for utilizing a controlled pump implanted into a patient connected to a multilumen catheter allowing delivery to and sampling from the brain or other organ for treatment of a cancer. The pump delivers a plurality of medicating agents, including viral and non-viral vectors for gene therapy and cell therapy at a controlled rate, corresponding to the specific needs of the patient. A catheter is implanted in or adjacent to the tumoral region. Fluid drawn from the tumor region to the pump via the multilumen catheter is analyzed within the pump by various biofeedback sensors. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. The method allows localized delivery of gene and cell therapy to a solid tumor or tumoral region, or to any other treatment area of interest within the patient.

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04-10-2012 дата публикации

Stimulatory effect estimation device, sleep depth estimation device, stimulatory effect estimation method, and vehicle control device

Номер: US20120253221A1
Принадлежит: Toyota Motor Corp

A stimulatory effect estimation device includes a stimulus generator 3 which applies a stimulus to a back seat passenger, an electroencephalogram 2 which measures the brain waves of the back seat passenger, a memory 4 , and an ECU 5 which specifies the brain wave indexes of stimulatory effects which surface in response to the stimuli both when the passenger is awake and when the passenger is asleep from the brain waves measured by the electroencephalogram 2 when a stimulus is applied from the stimulus generator 3 while the passenger is awake and the brain waves measured by the electroencephalogram 2 when a stimulus is applied from the stimulus generator 3 while the passenger is asleep. The ECU 5 estimates stimulatory effects when the passenger is asleep from stimulatory effects when the passenger is awake using a conversion model for converting the stimulatory effect when the passenger is awake and the stimulatory effects when the passenger is asleep on the basis of the brain wave indexes which surface when the same stimulus is applied when the passenger is awake and when the passenger is asleep, and selects a stimulus which is applied to the back seat passenger on the basis of the relationship between the stimulatory effects and the changes in sleep depth.

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06-12-2012 дата публикации

Ventricular assist device cannula and ventricular assist device including the same

Номер: US20120310037A1
Принадлежит: LibraHeat Inc V

Provided is a ventricular assist device cannula, and more particularly, a ventricular assist device cannula with electrodes. An exemplary embodiment of the present invention provides a ventricular assist device cannula with electrodes, including: a connecting tube connecting an incision of a body tissue and a ventricular assist device so that blood can flow; and electrodes connected with the connecting tube and contacting the incision of the body tissue to transfer an electric signal to the body tissue.

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24-01-2013 дата публикации

Patient-controlled analgesia safety system

Номер: US20130023820A1
Принадлежит: Individual

The patient-controlled analgesia (PCA) safety system includes a housing with a hollow compartment. A display and keypad are disposed on one side of the for display of monitoring data and selective commands respectively. An analgesic module and an antidote module are detachably mounted inside the compartment. A control module is disposed inside the housing. A vital signs monitor is connected to the control module to monitor a patient. In the event of abnormal readings due to, e.g., overdose or drug-related complications, the control module can automatically administer an antidote to the analgesia. The control module can also alert a nurse monitor and/or other personnel wirelessly to insure someone is notified of the potential emergency. The PCA safety system can also be provided in a separate safety module having a detachably mounted antidote module.

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28-02-2013 дата публикации

Battery Management for a Breathing Assistance System

Номер: US20130047983A1
Принадлежит: COVIDIEN LP

A method for providing battery security in a breathing assistance system configured to provide breathing assistance to a patient is provided. A battery security system of the breathing assistance system receives battery data from a battery received in the breathing assistance system, and analyzes the received battery data to determine whether the battery is approved for use in the breathing assistance system. If the battery is determined to be approved for use in the breathing assistance system, the battery is allowed to provide power to the breathing assistance system. If the battery is not determined to be approved for use in the breathing assistance system, the battery is prevented from providing power to the breathing assistance system.

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28-02-2013 дата публикации

Activity Sensing Techniques for an Infusion Pump System

Номер: US20130053820A1
Автор: Deb Ruppert, Mark C. Estes
Принадлежит: Asante Solutions Inc

Some embodiments of a wearable infusion pump system can include a pump device having a drive system to dispense a medicine to a user, an activity sensor that detects a possible change in an activity level of the user, and a controller to activate the drive system to dispense the medicine to the user. The controller device can query the user to indicate whether a detected activity level of the user represents an actual change in the activity level of the user. The controller device can alter the medicine dispensing schedule based on the user indicated changes in activity level.

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16-05-2013 дата публикации

Anesthetic Inhalation Aid Device and Attachment Used for the Same

Номер: US20130118484A1
Автор: Naoyuki ISHIKITA
Принадлежит: Individual

An inhalation mask, an artificial nose unit, an anesthetic gas concentration detector, an extension tube, an anesthesia attachment, and an elastic bag are in communicative connection in sequence. The elastic bag has a mixing chamber formed therein and has an anesthetic inlet, an air inlet, and an outlet port each formed at the boundary to the exterior. The anesthesia attachment includes a hollow structure and an evaporation injector syringe. The outlet port of the elastic bag is in communicative connection with the hollow structure through its opening, and the evaporation injector syringe tightly mates with the interior of another opening. The anesthetic introduced into the mixing chamber is vaporized and then mixed with air introduced from the air inlet into mixed gas. The mixed gas is supplied from the outlet port to the inhalation mask by compressing the elastic bag or other procedures.

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23-05-2013 дата публикации

Management of patient fall risk

Номер: US20130127620A1
Принадлежит: Cerner Innovation Inc

Methods, computer systems, and computer-storage media are provided for facilitating the management of a patient's fall risk. It is determined that the patient has previously been classified as a fall risk. Inputs are automatically received from fall risk sensors located in the patient's clinical care room, and, based on the inputs received from the fall risk sensors, it is determined that the patient is currently at risk for falling. Alerts are initiated and settings for components within the clinical care room are adjusted to decrease the patient's fall risk.

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06-06-2013 дата публикации

Oxygen regulation with at least two spo2 monitors and automatic recognition of a signal having a higher rating

Номер: US20130139817A1
Принадлежит: Draëger Medical GmbH

A process and a device for oxygen regulation of a patient having at least two SPO 2 monitors and a control for automatic recognition of which measurements are more reliable. The measurement from one or more of the two SPO 2 is used to control the oxygen concentration delivered to a patient based on a comparison of the measurements from the at least two SPO 2 monitors.

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25-07-2013 дата публикации

Apparatus, system, and method for modulating consolidation of memory during sleep

Номер: US20130190556A1
Принадлежит: Individual

Devices, systems and methods to modify memory and/or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement/relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep.

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17-10-2013 дата публикации

Multimodal dialysis system

Номер: US20130274642A1
Принадлежит: MEDTRONIC INC

A dialysis device for operation in multiple modes and for maintaining a known gradient of potassium ion or other electrolyte between the blood of a patient and a dialysate fluid is described. The dialysis device is capable of being used for hemodialysis or peritoneal dialysis, and the dialysis device is capable of operation with a dialysate purification unit outside of a clinical setting or with a supply of water that can be supplied in a clinical setting. The dialysis device has a composition sensor containing a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of the patient's blood and the dialysate fluid and an infusate pump operated to adjust a potassium ion concentration in the dialysate fluid based at least in part on data from the composition sensor.

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31-10-2013 дата публикации

Drug Delivery System And Method For Conscious Sedation/Analgesia

Номер: US20130284168A1
Принадлежит: Piramal Critical Care Inc

Inhalant anesthetics are developed with a number of properties including rapid onset and recovery, controllability, and, ideally, a broad safety profile. The efficacy of these agents is measured by their ability to create anesthesia within the framework of the other desirable properties. The instant invention focuses on the dosage level where analgesia occurs but amnesia or lack of consciousness does not. In addition to identifying the dosage level where pain is sharply reduced or eliminated but awareness remains, a delivery system for safe and effective delivery of the agent is described.

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05-12-2013 дата публикации

Airway device, airway assist device and the method of using same

Номер: US20130324798A1
Принадлежит: Arcangelo Michele Iusco, Robert Molnar

An airway device is provided for opening a patient's airway. The airway device provides dual tubes which allow the patient to breathe on his/her own, to be ventilated, or to be intubated. The airway device includes a camera which provides constant visualization of the patient's tissues during insertion of the airway device and during the entire medical procedure. A transmission lumen monitors heart and breath sounds. Information from the camera and the transmission lumen is relayed to a microprocessor to allow for monitoring which may be remote. An airway assist device may be used with the airway device for properly positioning the patient's tongue is also disclosed. The airway assist device is inserted into the patient's vallecula to manipulate the patient's tongue.

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12-12-2013 дата публикации

Depth of consciousness monitor

Номер: US20130331660A1
Принадлежит: Masimo Corp

The present disclosure relates to physiological monitoring to determine the depth of consciousness of a patient under sedation. The monitor includes an EEG sensor and a depth of consciousness monitor. The depth of consciousness monitor can utilize treatment data, such as patient data and/or drug profile information with an EEG signal to determine whether the patient is adequately sedated.

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09-01-2014 дата публикации

Childbirth labor coach with paced breathing

Номер: US20140007877A1
Принадлежит: Koninklijke Philips NV

A system ( 10 ) configured to prompt a subject ( 12 ) to consciously alter one or more breathing parameters during childbirth. The system includes a pressure generator ( 14 ) that generates a pressurized flow of breathable gas for delivery to an airway of the subject during childbirth and a processor ( 22 ) that controls the pressure generator to adjust one or more gas parameters of the gas in the pressurized flow of breathable gas to provide breathing cues to the subject in accordance with a breathing regime associated with labor contractions, wherein the breathing cues prompt the subject to consciously alter one or more breathing parameters of respiration.

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06-03-2014 дата публикации

Safeguarding measures for a closed-loop insulin infusion system

Номер: US20140066885A1
Принадлежит: Medtronic Minimed Inc

Processor-implemented methods of controlling an insulin infusion device for a user are provided here. A first method obtains a current insulin on board (IOB) value that estimates active insulin in the user, and compensates a calculated insulin infusion rate in response to the obtained IOB value. A second method supervises the operation of a glucose sensor by obtaining and processing insulin-delivered data and glucose sensor data for the user. An alert is generated if the second method determines that a current glucose sensor value has deviated from a predicted sensor glucose value by at least a threshold amount.

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06-01-2022 дата публикации

AR/VR/XR ASSISTANCE

Номер: US20220001134A1
Автор: Tran Bao, Tran Ha
Принадлежит:

A reality system includes a display aimed at a retina, the display providing 3D images with different depth view points; a glass to selectably turn on or off view of an outside environment in front of the person's eye; a processor coupled to the camera and to the glass to selectably switch between augmented reality and virtual reality; and a wireless transceiver coupled to the transceiver to communicate with a remote processor. 1. A reality system comprising:a display lens removably contacting an eye;a processor coupled to a cameras and to the display lens, the processor providing visual assistance to the person by running code for panorama stitching, the processor further providing augmented vision including automated object recognition and facial recognition with limited information processing by determining a position and shape of an object based on edge locations in time-correlated images from two cameras, and determining motion from successive pairs of images after subjecting the images to edge detection or thresholding and then scaling, cropping or centering the recognized object or face to aid the person; anda wireless transceiver coupled to the transceiver to communicate with a remote processor.2. The system of claim 1 , wherein the remote processor is in a mobile phone claim 1 , and wherein the processor selectably switches between augmented reality and virtual reality claim 1 , the processor includingcode to perform motion tracking and understanding an environment with points or planes using accelerometer sensor and estimating light or color in the environment using one video camera without a depth sensor in a mobile phone;code to capture images from a plurality of angles of the environment;code to acquire sensor data from sensors and optimize features extracted from each image and sensor data, where a feature conveys data unique to the image at a specific pixel location, comprising: a learning machine that determines content to be presented based on ...

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01-01-2015 дата публикации

METHODS AND APPARATUS FOR THE SYSTEMIC CONTROL OF VENTILATORY SUPPORT IN THE PRESENCE OF RESPIRATORY INSUFFICIENCY

Номер: US20150000667A1
Автор: Bassin David John
Принадлежит:

A method and apparatus for providing ventilatory assistance to a spontaneously breathing patient an error signal () is computed that is the difference between a function of respiratory airflow () over a period of time and a target value (). Using a servo loop, air is delivered to the patient at a pressure that is a function of the error signal, the phase of the current breathing cycle, and a loop gain that varies depending on the magnitude of the error signal. The loop gain increases with the magnitude of the error signal, and the gain is greater for error signals below a ventilation target than for error signals above the ventilation target value. The target value () is an alveolar ventilation that takes into account the patient's physiologic dead space. 1. A method for providing ventilatory assistance to a spontaneously breathing patient comprising continuously repeating the steps of:determining respiratory airflow,computing a measure of the difference between a function of respiratory airflow over a period of time and a target value,determining the phase of the current breathing cycle, anddelivering air to the patient at a pressure that is a function of the product of (a) said difference measure, (b) the amplitude at the determined phase of the current breathing cycle of an amplitude-versus-phase template that is appropriate for a normal breathing cycle, and (c) a gain factor that varies depending on the magnitude of said difference measure.2. A method for providing ventilator assistance in accordance with wherein said gain factor increases with the magnitude of said difference measure.3. A method for providing ventilator assistance in accordance with wherein for equal difference measures below and above said target value claim 2 , the gain factor is greater for difference measures below said target value.4. A method for providing ventilator assistance in accordance with wherein said target value is an alveolar ventilation that takes into account the patient's ...

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07-01-2021 дата публикации

Remote smell technology

Номер: US20210000998A1
Принадлежит: University of North Texas

The present application relates to systems, methods, and computer-readable media for providing generating odors. In aspects, the disclosed methods may include generating, by a chemistry dispersion element, a signal configured to act upon a surface of a chemistry reservoir to disperse an odorous substance retained within the chemistry reservoir. The chemistry reservoir and the chemistry dispersion element may be disposed within a housing. The method also includes generating, by an air pump, a volume of air, and transporting, by an airflow pathway, the volume of air from the air pump to an air outlet. The volume of air passes through at least a portion of the housing as it flows through the airflow pathway from the air pump to the air outlet, and transports at least a portion of the odorous substance dispersed by the chemistry reservoir within the housing to the air outlet.

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07-01-2016 дата публикации

Dialysis implant and methods of use

Номер: US20160000984A1
Принадлежит: Sequana Medical AG

A device and methods for treating renal failure are disclosed. One embodiment of the device is an implantable peritoneal dialysis device. When in use, the device can have a semi-permeable reservoir implanted in the peritoneal cavity. The reservoir can receive blood waste and drain through one or more conduits, via a pump, to the biological bladder. Solids and/or a solution benefiting dialysis can be pumped to the reservoir and/or implanted in the peritoneal cavity.

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07-01-2016 дата публикации

SYSTEMS AND METHODS USING ESTIMATED GLOMERULAR FILTRATION RATES OF THE KIDNEYS IN THE NON-STEADY STATE

Номер: US20160001000A1
Принадлежит:

A system and method of determining the estimated glomerular filtration rate of the kidneys of a patient. The system and method obtains patient medical data, determines constants based on the patient medical data and using exactly one of the MDRD equation or the Cockroft-Gault equation, and determines the estimated glomerular filtration rate based on a relationship of measured creatinine levels and the determined constants. The estimated glomerular filtration rate is used to determine the dose of a medication of a type filtered by the kidneys, determine a temporal correlation of the introduction of a drug into a patient with changes in kidney function, determine the administration rate for dosing intravenous fluids, determine the efficacy of a medical treatment, and determine kidney function after transplantation or injury. 2. The computer-implemented method of claim 1 , wherein determining the dose further comprises:determining a standard dose of medicine for the patient based on one or more medical data; anddetermining an adjustment to the standard dose of medicine based at least in part on the estimated glomerular filtration rate of the kidney, andwherein the dose is the standard dose modified by the adjustment to the standard dose.3. The computer-implemented method of claim 1 , wherein determining the dose further comprises:determining a preferred blood concentration of the medicine for the patient; anddetermining the dose of medicine needed to attain the preferred blood concentration of the medicine in the patient.4. The computer-implemented method of claim 1 , wherein determining the dose further comprises:determining a preferred blood concentration of metabolites of the medicine for the patient; anddetermining the dose of medicine to needed attain the preferred blood concentration of metabolites of the medicine in the patient.5. The computer-implemented method of claim 1 , wherein determining the dose further comprises:determining a preferred range of blood ...

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07-01-2021 дата публикации

INFUSION SET FOR MEASURING VITAL SIGNALS OF A PATIENT COMPRISING A COMPLIANCE ELEMENT AND A REFLECTIVE ELEMENT

Номер: US20210001043A1
Принадлежит:

There is provided an IV infusion set comprising a patient access configured to connect to a vascular system of a patient, a source of medical fluid, an infusion line having one first end configured to connect to the source of medical fluid and one opposite second end configured to deliver the medical fluid towards the patient access, an infusion apparatus arranged on the infusion line, a sensor configured to emit a pressure signal indicative of a pressure of a medical fluid in the infusion line, and a control unit configured to receive the pressure signal and to determine a patient signal indicative of a vital signal of the patient based on the pressure signal. The IV infusion set further comprises a compliance element configured to attenuate pressure variations of medical fluid the infusion line, and a resistance element configured to reflect pressure waves moving along the infusion line. The sensor is arranged on the infusion line at a position downstream from the resistance element with respect to a direction of fluid flow along the infusion line from the medical fluid source towards the patient access. The infusion line may include a main infusion line and/or one or more auxiliary infusion lines connected to a main infusion line. 126-. (canceled)27. An IV infusion set , comprising:a patient access configured to connect to a vascular system of a patient;a source of medical fluid;an infusion line having at least one first end configured to connect to the source of medical fluid and at least one opposite second end configured to deliver the medical fluid towards the patient access, the infusion line defining at least a medical fluid path developing from the first end of the infusion line to the patient access, the second end of the infusion line being connected to the patient access, the source of medical fluid being coupled to the first end of the infusion line and configured to supply medical fluid to the infusion line;an infusion apparatus arranged on the ...

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02-01-2020 дата публикации

Sustained variable negative pressure wound treatment and method of controlling same

Номер: US20200000982A1
Принадлежит: Smith and Nephew Inc, Smith and Nephew PLC

Disclosed herein are systems and methods for providing reduced or negative pressure, and more particularly cyclical reduced pressure, to treat a wound. The system can include a wound dressing, a fluid collection container, a suction source, filters, and conduits. In addition, the system can include a control device and sensors. The sensors may be configured to monitor certain physiological conditions of a patient such as temperature, pressure, blood flow, blood oxygen saturation, pulse, cardiac cycle, and the like. Application of cyclical reduced pressure between two or more values below atmospheric pressure may be synchronized with the physiological conditions monitored by the sensors. Certain embodiments of the system utilize an air reservoir and one or more valves and pressure sensors or gauges to allow for rapid cycling of the level of reduced pressure within the wound dressing between two or more reduced pressure values.

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04-01-2018 дата публикации

SYSTEMS AND METHODS FOR MAINTAINING FLUID BALANCE

Номер: US20180001005A1
Автор: Casas Fernando
Принадлежит:

A signal processing circuit for controlling operation of an implanted ventricular assist device comprising an input module for receiving one or more signals of a patient from one or more sensors. A processor for processing the received signals is included, the processor configured to compare a total blood output on a left side of the patient's heart with a total blood output on a right side of the patient's heart; determine at least one from the group consisting of the presence of fluid imbalance between the left and right sides of the patient's heart and the absence of fluid imbalance between the left and right sides of the patient's heart based on the comparison; and when the presence of fluid imbalance is determined, control the implanted ventricular device to restore fluid balance between the left and right sides of the patient's heart. 1. A method for controlling fluid balance between pulmonary and systemic circulations of a patient having one or more ventricular assist devices , comprising:determining left ventricular cardiac output and right ventricular cardiac output;determining an output of blood from a left ventricular assist device of the patient, if the patient does not have a left ventricular assist device the determined output is 0;determining an output of blood from a right ventricular assist device of the patient, if the patient does not have a right ventricular assist device the determined output is 0;measuring a difference between (i) a sum of the left ventricular cardiac output and the output of blood from the left ventricular assist device and (ii) a sum of the right ventricular cardiac output and the output of blood from the right ventricular assist device; andwhen the measured difference exceeds a predetermined threshold, adjusting a parameter for control of at least one from the group consisting of the left ventricular assist device and the right ventricular assist device.2. The method of claim 1 , wherein the left ventricular cardiac output ...

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05-01-2017 дата публикации

MECHANICAL ASSIST DEVICE

Номер: US20170000935A1
Принадлежит:

Methods and apparatuses relate to an implantable device for providing contractile assistance to an organ. The device may include an actuator and anchors located on either side of the actuator. The anchors engage with oppositely positioned tissue walls of an organ chamber, and provide contractile assistance to the organ, repeatedly, at appropriate times. For example, the device may be implanted within the right ventricle, anchored to the right ventricular free wall and the ventricular septum. The device may function to bring the opposing walls of the ventricle toward one another, synchronized with the pacing of the heart, resulting in an improved ejection fraction of blood from the chamber. In some embodiments, the actuator includes a bladder that is configured to contract upon receiving an inflow of pressurized fluid therein. When the fluid exits therefrom, the bladder relaxes back to an initial, extended state. 1. A device for providing mechanical assistance to an organ , the device comprising:a first anchor adapted to engage with a first wall region of the organ;a second anchor adapted to engage with a second wall region of the organ; andan actuator coupled with the first anchor and the second anchor, and configured to move the first and second anchors relative to one another repeatedly between a contracted position where the anchors are moved toward each other to draw the first and second wall regions of the organ toward each other and an extended position where the anchors are moved away from each other relative to the contracted position to move the first and second wall regions away from each other.2. The device of claim 1 , wherein the actuator is located between the first and second anchors.3. The device of claim 1 , wherein at least one of the first anchor and the second anchor is configured to be retracted from engagement with the respective wall region of the organ.4. The device of claim 1 , wherein at least one of the first anchor and the second anchor ...

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05-01-2017 дата публикации

Method and device to monitor patients with kidney disease

Номер: US20170000936A1
Принадлежит: MEDTRONIC INC

A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.

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05-01-2017 дата публикации

BASAL RATE TESTING USING FREQUENT BLOOD GLUCOSE INPUT

Номер: US20170000943A1
Принадлежит:

An apparatus comprising a user interface configured to generate an electrical signal to start a basal insulin rate test when prompted by a user, an input configured to receive sampled blood glucose data of a patient that is obtained during a specified time duration, including a time duration during delivery of insulin according to a specified basal insulin rate pattern, and a controller communicatively coupled to the input and the user interface. The controller includes an insulin calculation module configured for determining at least one of an amount of basal insulin over-delivered and an amount of basal insulin under-delivered during the basal insulin rate test in trying to meet a target blood glucose baseline. Other devices and methods are disclosed. 1. An apparatus comprising:a user interface configured to generate an electrical signal to start a basal insulin rate test when prompted by a user;an input configured to receive sampled blood glucose data of a patient that is obtained during a specified time duration, including a time duration when insulin is delivered according to a specified basal insulin rate pattern; anda controller communicatively coupled to the input and the user interface, the controller including an insulin calculation module, wherein the insulin calculation module is configured to determine at least one of an amount of basal insulin over-delivered and an amount of basal insulin under-delivered during the basal insulin rate test in trying to meet a target blood glucose baseline.2. The apparatus of claim 1 , wherein the insulin calculation module is configured to determine the over-delivered amount and the under-delivered amount using a correction factor of the patient and a variance of a blood glucose level from the target blood glucose baseline.3. The apparatus of claim 2 , wherein the insulin calculation module is configured to determine the over-delivered amount and the under-delivered amount using an adjusted correction factor of the ...

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04-01-2018 дата публикации

SYSTEMS AND METHODS FOR MODEL-BASED OPTIMIZATION OF MECHANICAL VENTILATION

Номер: US20180001042A1
Принадлежит:

A mechanical ventilator () is connected with a ventilated patient () to provide ventilation in accordance with ventilator settings of the mechanical ventilator. Physiological values (variables) are acquired for the ventilated patient using physiological sensors (). A ventilated patient cardiopulmonary (CP) model () is fitted to the acquired physiological variables values to generate a fitted ventilated patient CP model by fine-tuning its parameters (). Updated ventilator settings are determined by adjusting model ventilator settings of the fitted ventilated patient CP model to minimize a cost function (). The updated ventilator settings may be displayed on a display component () as recommended ventilator settings for the ventilated patient, or the ventilator settings of the mechanical ventilator may be automatically changed to the updated ventilator settings so as to automatically control the mechanical ventilator. 1. A medical ventilator system comprising:a mechanical ventilator connected with a ventilated patient to provide ventilation to the ventilated patient in accordance with ventilator settings;physiological sensors configured to acquire measured values for the ventilated patient of monitored physiological variables;a cardiopulmonary modeling component comprising a microprocessor programmed to generate computed values for the ventilated patient of unmonitored physiological parameters based on the measured values for the ventilated patient of the monitored physiological variables and the ventilator settings,wherein the CP modeling component is programmed to generate the computed values for the ventilated patient of the unmonitored physiological parameters by operations includingfitting a ventilated patient CP model to the ventilated patient by fitting predictions of the ventilated patient CP model for the monitored physiological variables to the measured values for the ventilated patient of the monitored physiological variables in order to generate a fitted ...

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02-01-2020 дата публикации

Pressure support system and method of providing pressure support therapy to a patient

Номер: US20200001038A1
Принадлежит: Koninklijke Philips NV

A pressure support system for providing pressure support therapy to a patient, the pressure support device includes an airflow generator structured to generate a flow of breathing gas to the patient, a temperature conditioning unit structured to adjust a temperature of the breathing gas provided to the patient, and a processing unit structured to estimate a core body temperature of the patient for selected times of day based on one or more inputs and to control the temperature conditioning unit to adjust temperature of the breathing provided to the patient at the selected times of day based on the estimated core body temperatures of the patient.

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02-01-2020 дата публикации

APPARATUS, SYSTEMS, AND METHODS FOR HIS BUNDLE LEAD PLACEMENT

Номер: US20200001070A1
Принадлежит:

Apparatus, systems, and methods are provided for placing pacing leads or other devices within a patient's heart. In an exemplary embodiment, the apparatus includes a tubular member comprising a flexible distal portion defining a curvilinear shape in a relaxed state including a curved first region defining a first radius lying within a first plane, a substantially straight second region extending from the first curved region defining a first length, and a curved third region extending from the second region defining a second radius smaller than the first radius. 1. An apparatus for delivering a lead or other secondary device into a patient's heart , comprising:an elongate tubular member comprising a proximal end, a distal end sized for introduction into a patient's body, and a lumen extending therebetween,wherein the tubular member comprises a flexible distal portion defining a curvilinear shape in a relaxed state including a curved first region defining a first radius lying within a first plane, a substantially straight second region extending from the first curved region defining a first length, and a curved third region extending from the second region defining a second radius smaller than the first radius.2. The apparatus of claim 1 , wherein the third region extends out of the first plane.3. The apparatus of claim 1 , wherein the second radius of the third region lies within a second plane orthogonal to the first plane.4. The apparatus of claim 1 , wherein the tubular member terminates at a distal tip configured for placement against a wall of the patient's heart such that an outlet communicating with the lumen is positionable against the wall.5. The apparatus of claim 4 , further comprising a pair of electrodes on the distal end on opposite sides of the outlet.6. The apparatus of claim 5 , further comprising a processor coupled to the pair of electrodes for processing signals to identify when the distal tip is placed against a desired location of a wall of the ...

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02-01-2020 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR TREATING VESTIBULAR CONDITIONS

Номер: US20200001085A1
Автор: OWEN Samuel, TRUE Robert
Принадлежит: Otolith Sound Inc.

Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system. 1. A method , comprising:applying, via a vibratory device positioned over an area of a head of a user, a vibratory signal to the area of the head of the user such that the vibratory signal can be conducted via bone to a vestibular system of the user, the vibratory signal configured to cause a portion of the vestibular system to move in a manner equivalent to that of a vibratory signal (1) applied to an area overlaying a mastoid bone of the user and having (2) a frequency less than 200 Hz and a force level greater than 87 dB re 1 dyne and less than or equal to 100 dB re 1 dyne; andtreating, in response to applying the vibratory signal to the area of the head of the user, a physiological condition associated with the vestibular system.2. The method of claim 1 , wherein the vibratory device has a resonant frequency claim 1 , the method further comprising:supplying an electrical signal to the vibratory device to cause the vibratory device to vibrate to generate the vibratory signal that is applied to the area of the head of the user, the electrical signal having a signal frequency;measuring, using a sensor, information including at least one of: a current of the electrical signal, a voltage change of the electrical signal across the vibratory device, a magnetic field generated near the vibratory device, and an acceleration of the vibratory device; andadjusting the ...

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03-01-2019 дата публикации

SUSTAINED VARIABLE NEGATIVE PRESSURE WOUND TREATMENT AND METHOD OF CONTROLLING SAME

Номер: US20190001032A1
Принадлежит:

Disclosed herein are systems and methods for providing reduced or negative pressure, and more particularly cyclical reduced pressure, to treat a wound. The system can include a wound dressing, a fluid collection container, a suction source, filters, and conduits. In addition, the system can include a control device and sensors. The sensors may be configured to monitor certain physiological conditions of a patient such as temperature, pressure, blood flow, blood oxygen saturation, pulse, cardiac cycle, and the like. Application of cyclical reduced pressure between two or more values below atmospheric pressure may be synchronized with the physiological conditions monitored by the sensors. Certain embodiments of the system utilize an air reservoir and one or more valves and pressure sensors or gauges to allow for rapid cycling of the level of reduced pressure within the wound dressing between two or more reduced pressure values. 115.-. (canceled)16. A method of operating a negative pressure wound therapy apparatus , the method comprising:applying, via a fluid flow path, reduced pressure from a suction source to a wound dressing placed over a wound;monitoring a temperature at the wound using a sensor positioned at least partly in the wound or the wound dressing or positioned adjacent to the wound dressing; andadjusting the reduced pressure from the suction source by cycling the reduced pressure from the suction source between two different negative pressure values according at least to the temperature at the wound.17. The method of claim 16 , wherein said adjusting comprises adjusting a frequency of the reduced pressure from the suction source according at least to the temperature at the wound.18. The method of claim 16 , wherein said adjusting comprises adjusting the reduced pressure from the suction source in response to determining that the temperature at the wound satisfies a threshold.19. The method of claim 16 , wherein said adjusting comprises adjusting the ...

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03-01-2019 дата публикации

HEART FAILURE RECOVERY DEVICE AND METHOD OF TREATMENT

Номер: US20190001037A1
Автор: Bonde Pramod
Принадлежит:

A heart failure recovery device includes a fluid pump having an inlet and an outlet in fluid communication with a pump reservoir, and a pumping element disposed within the pump reservoir, the pumping element including a protrusion that in an active state is configured to rotate and move fluid away from the inlet and towards the outlet. A receiver coil can be electrically coupled to the fluid pump and is configured to subcutaneously absorb electromagnetic energy for powering the fluid pump. In certain embodiments, an implantable port provides fluid access to the pump reservoir for cleaning and maintaining the fluid pump. In other embodiments, a valve closes fluid access to at least one of the inlet and the outlet during periods when the device is not being used for treatment. 1. A heart failure recovery device comprising:a fluid pump comprising an inlet and an outlet in fluid communication with a pump reservoir, and a pumping element disposed within the pump reservoir, the pumping element comprising a protrusion that in an active state is configured to rotate and move fluid away from the inlet and towards the outlet;a receiver coil electrically coupled to the fluid pump, the receiver coil configured to subcutaneously absorb electromagnetic energy for powering the fluid pump; anda valve configured to open in the active state and fluidly seal at least one of the inlet and the outlet in an inactive state.2. A system comprising the heart failure recovery device of claim 1 , the system comprising:an external coil configured to send electromagnetic energy to the receiver coil for powering the fluid pump while the receiver coil is implanted subcutaneously.3. The heart failure recovery device of claim 1 , wherein the pumping element comprises an impeller.4. The heart failure recovery device of claim 3 , wherein the pump reservoir has a substantially circular cross-sectional profile.5. The heart failure recovery device of claim 1 , wherein the valve is an iris valve.6. The ...

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03-01-2019 дата публикации

Medical connectors and methods of use

Номер: US20190001114A1
Автор: Thomas F. Fangrow
Принадлежит: ICU Medical Inc

Some embodiments disclosed herein relate to a medical connector with an internal cavity with an internal closure system having a dome valve configured to resist retrograde fluid flow caused by various sources, including patient activity and fluid administration activity. A proximal closure system with a seal member and a moveable plug are also located within the internal cavity.

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06-01-2022 дата публикации

FIELD UPDATE OF AN AMBULATORY INFUSION PUMP SYSTEM

Номер: US20220005602A1
Автор: Ludolph Don
Принадлежит:

Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described. 1. An ambulatory fluid delivery device , comprising:a user interface that a user operates to input directions and data that determine the dosing of a medicament to a patient;a liquid drug repository that contains the medicament;a pump fluidly connected to the liquid drug repository;an electrical controller configured to direct the pump to release the medicament; and data regarding administered doses of the medicament;', 'one or more device history logs of the fluid delivery device;', 'an operating system of fluid delivery device;', 'user profile information;', 'identifying information regarding the fluid delivery device; and', 'safety protocols for the fluid delivery device; and, 'a digital storage component, operably connected to the electrical controller, configured to store'} receive software updates sent from a qualified source;', 'verify the appropriateness of the software updates for the fluid delivery device based upon the identifying information and device history logs;', 'automatically install the software updates;', 'update the device history logs; and', 'perform tests conforming to the safety protocols after installation of the software., 'a signal processing component that sends and receives electrical data to and from the controller, wherein the fluid delivery device is configured to'}2. The ambulatory fluid delivery device of claim 1 , wherein software updates are received after the user requests the software update.3. The ambulatory fluid delivery device of claim 1 , wherein the software updates are automatically received by the ambulatory fluid delivery device.4. The ambulatory fluid delivery device of claim 1 , wherein the ...

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13-01-2022 дата публикации

APPARATUS AND METHOD FOR WOUND VOLUME MEASUREMENT

Номер: US20220008640A1
Принадлежит:

A method and apparatus for measuring a volume of a wound are described, the method comprising the steps of: applying a dressing over a wound, the volume of which is to be measured, the dressing including at least a sealing drape over the wound so as to create a sealed wound cavity; creating a vacuum in said wound cavity by vacuum pump means so as to produce a predetermined vacuum in the wound cavity; measuring a volume of air extracted from said wound cavity in producing said predetermined vacuum; and, calculating a volume of said wound. 116-. (canceled)17. A negative pressure wound therapy device comprising:a negative pressure source configured to be connected to a wound via a fluid flow path and to provide negative pressure to the wound; and monitor a cumulative fluid flow in the fluid flow path, the cumulative fluid flow comprising fluid flow due to operation of the negative pressure source and fluid flow due to a leak in the fluid flow path, and', 'provide an indication based on the cumulative fluid flow., 'a controller programmed to operate the negative pressure source, the controller further programmed to18. The device of claim 17 , wherein the controller is programmed to:determine a rate of the leak; andprovide an indication of the rate of the leak.19. The device of claim 18 , wherein the controller is programmed to:determine the rate of the leak responsive to the negative pressure operating in a steady state.20. The device of claim 19 , wherein in the steady state claim 19 , the rate of the leak is equivalent to the cumulative fluid flow.21. The device of further comprising a pressure sensor configured to measure pressure in a fluid flow path claim 18 , wherein the steady state is determined based on the measured pressure.22. The device of wherein the pressure sensor is configured to be positioned in the fluid flow path between the negative pressure source and a wound dressing covering the wound.23. The device of further comprising a display configured to ...

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13-01-2022 дата публикации

Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device

Номер: US20220008669A1
Принадлежит: Pneuma Respiratory Inc

A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 μm, so as to target the pulmonary system of the user.

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13-01-2022 дата публикации

METHOD AND SYSTEM FOR FACILITATING THE TRANSITION BETWEEN A CONSCIOUS AND UNCONSCIOUS STATE

Номер: US20220008688A1
Автор: Kochman Cary
Принадлежит:

A system and method for facilitating and maintaining various states of a user consciousness, including the transition between a conscious and unconscious state, is provided. The system and method include use of a smart device having a user interface, a biometric sensor coupled to a user and configured to transmit the user's biometric data to the smart device and an environmental sensor configured to transmit environmental data to the smart device. The smart device controls one or more environmental systems proximate the user and an audio/visual device proximate the user to facilitate transitioning the state of the user. 120-. (canceled)21. A system for enhancing a desired user state comprising:a smart device having a user interface configured to provide user feedback input to the smart device;a first biometric device coupled to the smart device for transmitting a first biometric data from a user to the smart device;a first environmental sensor for transmitting a first environmental data proximate the user to the smart device;a first environmental device proximate the user coupled to the smart device;an audio/visual device proximate the user coupled to the smart device;wherein the smart device controls the environmental device and the audio/visual device in response to data received from the first biometric device, the first environmental sensor and user feedback input received from the user interface to effect a desired state of the user.22. The system of further comprising a second biometric device coupled to the smart device for transmitting a second biometric data from the user to the smart device.23. The system of further comprising a second environmental sensor for transmitting a second environmental data proximate the user to the smart device.24. The system of further comprising a second environmental device proximate the user coupled to the smart device.25. The system of wherein the audio/visual device is controlled by the smart device to produce a desired ...

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13-01-2022 дата публикации

Methods and systems for neural stimulation via visual stimulation

Номер: US20220008746A1
Принадлежит: Cognito Therapeutics Inc

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include eyeglasses, a photodiode positioned to detect ambient light, light sources, and an input device. The system can include a neural stimulation system that retrieves a profile and selects a light pattern having a fixed parameter and a variable parameter. The neural stimulation system can set a value of the variable parameter of the light pattern, construct an output signal, and then provide the output signal to the light sources to direct light towards the fovea.

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08-01-2015 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR CHANGING THERAPEUTIC AEROSOL SIZE AND IMPROVING EFFICIENCY OF VENTILATION AND AEROSOL DRUG DELIVERY

Номер: US20150007817A1
Принадлежит: Virginia Commonwealth University

A mixer-heater device provides controllable reduction in aerosol droplet size. Additionally, an intermittent delivery mode for administering an aerosol to a patient may take into account patient expiration and reduce aerosol losses without prolonging treatment time. Depositional losses in aerosol delivery systems may be reduced by streamlining the three dimensional geometry of conduits which change stream direction or flow path diameter. Ventilation systems may also benefit from streamlined components, in particular Y-connectors, with resulting advantages such as reduced rebreathed CO. 1. A mixer-heater device for reducing aerosol droplet size , comprising:a mixing region configured to admit aerosol droplets at an inlet; anda channel portion connected to said mixing region, said channel portion including a center channel having at least two opposing planar walls,wherein said center channel is configured to conduct an aerosol stream comprising said aerosol droplets in a first direction and said at least two opposing planar walls are configured to heat said aerosol stream within said center channel to 28 to 70° C. to reduce aerosol droplet size.2. The mixer-heater device of claim 1 , wherein said at least two opposing planar walls are configured to heat said aerosol stream within said interior of said center channel to 30 to 42° C.3. The mixer-heater device of claim 1 , further comprising side passages separated from said center channel by said at least two opposing planar walls claim 1 , said side passages being configured to conduct gas streams in a second direction which is opposite said first direction.4. The mixer-heater device of claim 3 , wherein said at least two opposing planar walls heat said aerosol stream within said center channel by transferring heat from said gas streams in said side passages to said aerosol stream within said center channel.5. The mixer-heater device of claim 3 , wherein said mixing region is configured to admit gas recycled from said ...

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08-01-2015 дата публикации

SYSTEM AND METHOD FOR DETERMINING A TARGET SUBJECT INTERFACE TEMPERATURE BASED ON A BASELINE TEMPERATURE

Номер: US20150007821A1
Принадлежит:

The present disclosure pertains to a pressure support system configured to provide pressure support therapy to a subject, wherein the pressure support system comprises a subject interface heater configured to controllably heat a pressurized flow of breathable gas to a target temperature that is offset from a baseline temperature. The breathable gas baseline temperature target offset ensures the gas delivered to the subject is delivered at a comfortable temperature and/or humidity level that does not cause airway dryness or result in condensed water in the subject interface. In one embodiment, the pressure support system comprises one or more of a pressure generator, a subject interface, a subject interface heater, one or more subject interface temperature sensors, one or more baseline temperature sensors, one or more general sensors, a humidifier, a user interface, a processor, electronic storage, and/or other components. 1. A pressure support system configured to provide temperature controlled pressure support to a subject , the pressure support system comprising:a pressure generator configured to generate a pressurized flow of breathable gas for delivery to an airway of the subject;a subject interface configured to deliver the pressurized flow of breathable gas to the airway of the subject;a subject interface heater configured to controllably heat the pressurized flow of breathable gas in the subject interface;one or more baseline temperature sensors configured to generate one or more output signals conveying information related to a baseline temperature; and a baseline temperature module configured to determine the baseline temperature based on the output signals generated by the baseline temperature sensors;', 'an offset temperature module configured to obtain receive user selection of a temperature offset;', 'a target temperature module configured to determine a target temperature based on the baseline temperature and the temperature offset; and', 'a subject ...

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08-01-2015 дата публикации

METHOD FOR CALIBRATING THE LEVEL OF OXYGEN IN RESPIRATORY GAS RELATED TO THE LEVEL OF OXYGEN IN THE BLOOD CIRCULATION OF AN INDIVIDUAL

Номер: US20150007823A1
Принадлежит:

The present invention relates to a method for calibrating, or adjusting, the level of oxygen in respiratory gas related to the level of oxygen in the blood circulation of the individual, comprising providing a level of oxygen in the gas flow passing into, or out, of the respiratory system of the individual and producing a corresponding first output, providing a level of oxygen in the blood circulation of the individual and producing a corresponding second output, providing a computer for receiving and storing at least two measurements, each measurement being the concurrent output of said first output and said second output within a data structure, in which the two stored outputs are mutually related, in data storage means associated with the computer, the at least two measurements being conducted at respective levels of oxygen in the gas flow passing into the respiratory system, and calibrating the level of oxygen in the gas value in response to a delay between the level of oxygen in the blood circulation of the individual and the level of oxygen in the gas flow passing into, or out, of the respiratory system of the individual. 1. A method for calibrating the level of oxygen in respiratory gas related to the level of oxygen in the blood circulation of an individual , comprising:providing a level of oxygen in the gas flow passing into, or out, of the respiratory system of the individual and producing a corresponding first output,providing a level of oxygen in the blood circulation of the individual and producing a corresponding second output,providing a computer for receiving and storing at least two measurements, each measurement being the concurrent output of said first output and said second output within a data structure, in which the two stored outputs are mutually related, in a data storage means associated with the computer, the at least two measurements being conducted at respective levels of oxygen in the gas flow passing into the respiratory system, ...

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12-01-2017 дата публикации

Wireless sensors and corresponding systems and methods for intra-operative nerve root decompression monitoring

Номер: US20170007146A1
Принадлежит: WARSAW ORTHOPEDIC INC

A sensor including an array of pins, a sensing element, a control module, and a physical layer module. The array of pins or needles is configured to be inserted in tissue of a patient. The sensing element is separate from the array of pins or needles and is configured to (i) detect a first parameter of the tissue, and (ii) generate a first signal indicative of the first parameter. The control module is configured to (i) receive the first signal, (ii) monitor a second parameter of the tissue based on a second signal received from the array of pins or needles, and (ii) generate a third signal based on the first signal and the second parameter, where the third signal is indicative of a level of decompression of a nerve of the patient. The physical layer module is configured to wirelessly transmit the third signal from the sensor to a console interface module or a nerve integrity monitoring device.

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12-01-2017 дата публикации

GI-ENDOCRINE DRUG DELIVERY DEVICE AND METHOD OF USE

Номер: US20170007434A1
Автор: Rothkopf Michael
Принадлежит: Hamilton Scientific, Ltd.

Shown are a device, system and method that improve the diabetes care of a patient that has undergone gastric surgery. The device provides continuously or intermediate monitoring at various intervals before and after meals of several sensors to perceive, among other things, the blood glucose level, EKG/heart rate and volume of meals a patient has consumed. Readings are sent to a control unit that receives input from at least one of: a meal sensor, glucose monitor, and EKG sensor to control a drug delivery unit that doses a prescribed agent at a specific quantity and time based on the readings to provide proper diabetes care for the patient. Components of the system such as the meal sensor glucose monitor, EKG sensor, control unit and drug delivery device may be implanted subcutaneously in the patient or outside the patient and may communicate with each other either wirelessly or may be directly wired together. 1. A gastric drug delivery device for improving diabetes patient care , comprising:a meal sensor apparatus having a base; the base defining a chamber;a pressure transducer disposed within the meal sensor apparatus, and the pressure transducer in fluid communication with the chamber;a gastric band bladder in fluid communication with the chamber, and wherein deflection of the band bladder causes a pressure differential in the chamber that is readable by the transducer.2. The gastric drug delivery device of claim 1 , further including a control unit that receives information from the transducer and determines a volume food consumed based on corresponding waveforms of the pressure differential read by the pressure transducer.3. The gastric drug delivery device of wherein the control unit further includes a memory to record at least one of a frequency of meals claim 2 , and a volume of meals.4. The gastric drug delivery device of wherein information from the transducer to the control unit is sent either by wireless connection or wire connection.5. The gastric drug ...

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14-01-2016 дата публикации

System for Providing Continuous Systolic Blood Pressure Measurement to Maintain Permissive Hypotension

Номер: US20160007863A1
Принадлежит:

A system for maintaining permissive hypotension in a patient includes monitoring of blood perfusion and pressure, combining blood perfusion and pressure data to determine systolic blood pressure, monitoring for detection of systolic blood pressure below a critical threshold value, and providing an alert to perfusion options to maintain permissive hypotension. The system may be adapted to adjust the critical threshold value for systolic blood pressure as treatment progresses. 1. A system for monitoring systolic blood pressure of a patient , comprising:a blood perfusion monitoring means;a pressure monitoring means;a means for combining blood perfusion data collected by the blood perfusion monitoring means and pressure data collected by the pressure monitoring means to determine systolic blood pressure, comparing the collected data to data stored in memory, and an alerting means for alerting a caregiver as to perfusion options to maintain permissive hypotension in the patient, based on the intermittent determination of current systolic blood pressure and by monitoring for detection of systolic blood pressure below a critical threshold value.2. The system of which is capable of finding current systolic blood pressure in addition to monitoring for a reduction in systolic blood pressure below a critical threshold followed by finding the new current systolic blood pressure as treatment ensues.3. The system of claim 1 , where the blood pressure monitoring components consists of a mechanically inflating cuff or mechanically induced pressure band around any part of an extremity capable of producing small incremental step wise increases or decreases in pressure around any part of an extremity.3. The system of where the perfusion monitoring component used in conjunction with the pressure producing component in is chosen among a pulse plethysmography sensor claim 1 , a piezoelectric sensor claim 1 , applanation tonometry claim 1 , Doppler signal claim 1 , light spectroscopy ...

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12-01-2017 дата публикации

EXTENDABLE AIR DELIVERY SYSTEM AND AIR DELIVERY METHOD

Номер: US20170007789A1
Автор: Chou Chang-An
Принадлежит:

An extendable air delivery system and a method for deciding a delivery mode therein are provided. The extendable air delivery system includes a PAP device for supplying a breathable pressured air to a patient and a sensing device to acquire physiological information from the patient by at least a sensor. The PAP device has two operations modes which are exchangeable while the air is supplied to the patient based on the connection or disconnection of the sensing device. When the sensing device is not connected to the PAP device, the PAP device enters a preset independent operation mode and performs a preloaded first air delivery behavior. When the sensing device is not connected, the PAP device enters a common operation mode, and during the common operation mode, based on the acquired physiological information, the sensing device generates a signal/data for deciding a second air delivery behavior of the PAP device. 1. A method for deciding a delivery mode of an air delivery system , the method comprising steps of:a) providing an air delivery system, which includes a PAP device for supplying a pressured breathable air to a patient, and a sensing device having at least a sensor for acquiring physiological information from a patient, wherein the PAP device and the sensing device are configured to be able to connect to or disconnect from each other;b) initiating the PAP device to start supplying the breathable air to the patient;c) while the breathable air is supplied to the patient, the PAP device detecting if the sensing device is connected therewith; andd1) if the sensing device is not connected with the PAP device, the PAP device enters a preset independent operation mode and performs a preloaded first air delivery behavior while supplying the breathable air to the patient; ord2) if the sensing device is connected with the PAP device, the PAP device enters a common operation mode, and during the common operation mode:based on the acquired physiological information, ...

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14-01-2016 дата публикации

SELF-CONTAINED HEART PUMP, AND METHOD IMPLEMENTED IN SUCH A PUMP

Номер: US20160008527A1
Автор: GARRIGUE Stéphane
Принадлежит:

A heart pump includes: 1. A Heart pump configured to be inserted partly into a systemic ventricle of a heart , through a wall of the heart , the heart pump comprising:a housing configured to be positioned inside the systemic ventricle in such a way as to draw up blood inside the systemic ventricle and to discharge the blood inside the systemic ventricle and through its sigmoid valves of the systemic ventricle,an impeller configured to be inserted inside the housing,a motor connected to the housing,a sealing and fixing membrane fastened to and around the motor and configured to secure the heart pump to the wall of the heart and to partly arrange the motor outside the systemic ventricle,a management unit comprising a power supply, and an impeller control unit; anda wired link between the management unit and the impeller.2. Heart pump according to claim 1 , wherein the sealing and fixing membrane is circular thereby being configured to ensure a complete seal and secure the heart pump to the bottom part of the heart near the apex of the heart.3. Heart pump according to claim 1 , wherein the impeller is of the rotative type and comprises a propeller shaft arranged in the housing.4. Heart pump according to claim 1 , wherein the impeller is of the rotative type and comprises an Archimedes screw or “worm” shaft arranged in the housing.5. Heart pump according to claim 1 , wherein the housing is a longilinear cylinder claim 1 , a side wall of which is perforated in such a way as to enable a discharge of drawn blood claim 1 , and an axis of rotation of which is facing corresponding sigmoid valves.6. Heart pump according to claim 1 , wherein the management unit is biocompatible and is configured to be positioned inside the patient in the epigastric region.7. Heart pump according to claim 1 , wherein at the motor is removable.8. Heart pump according to claim 1 , wherein the power supply comprises at least one rechargeable battery.9. Heart pump according to claim 1 , further ...

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14-01-2016 дата публикации

A SYSTEM AND METHOD FOR SYNCHRONIZATION OF BREATHING IN A MECHANICAL VENTILATOR

Номер: US20160008559A1
Автор: Tiedje Mikael
Принадлежит:

Example embodiments presented herein are directed towards a system, and corresponding method, for providing ventilation synchronization between breathing gas supplied by a mechanical ventilator and the breathing needs of a patient. In providing the ventilation synchronization, a total amount of energy required during an inspiratory phase of breathing is calculated. Based on the calculated energy, a decay factor is determined. The decay factor is supplied to an inspiratory triggering system in order to provide the ventilation synchronization. 1. A method , in a mechanical ventilator , for ventilation synchronization , the method comprising:receiving, from a flow sensor, a mass flow signal;receiving, from a pressure sensor, a pressure signal;calculating a total amount of energy during an inspiratory phase of breathing based, at least in part, on the pressure and mass flow signals;determining a decay factor based, in-part, on the total amount of energy; andapplying said decay factor, during an estimated time slot, to an inspiratory triggering system, said inspiratory trigger system providing a control signal altered according to said decay factor, such that a breathing phase of the mechanical ventilator is synchronized, or substantially synchronized, with a breathing phase of a patient.2. The method of claim 1 , wherein the receiving further comprises receiving the mass flow signal during an inspiratory breathing phase.3. The method of claim 1 , wherein the receiving further comprises receiving the pressure signal during an inspiratory breathing phase.4. The method of claim 1 , wherein the calculating further comprises summing a total amount of kinetic energy and a total amount of static energy claim 1 , wherein the kinetic energy is derived from the mass flow signal and the static energy is derived from the pressure signal.5. The method of claim 4 , further comprising calculating the total amount of kinetic energy.6. The method of claim 5 , wherein the calculating ...

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14-01-2016 дата публикации

Relaxation apparatus and method

Номер: US20160008568A1
Принадлежит: Matthew Markert, Sarah Beth Attia

A relaxation dome apparatus including a curved shell element which creates a microenvironment substantially surrounding the head, neck, and torso of a user person, wherein the interior surface of the shell facing the user person forms a relatively smooth regular curved surface. The apparatus includes an individual seating space, audio transducers configured to produce at least two sound signals proximate the user person's head, and a user interface to guide the user in obtaining a personal relaxation experience without need for an attendant, and for the purposes of collecting data. The apparatus may include combinations of visible light stimuli, biofeedback or neurofeedback data collection sensors, audio tracks which may include monaural, isochromic or binaural beats, and microcrystalline ceramic tiles. A database of aggregated user data and an Internet connection may each enable broadened therapy experiences for users.

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14-01-2021 дата публикации

System and method for sleep disorders: screening, testing and management

Номер: US20210007659A1
Автор: Ree Cherng, Suzanne Shugg
Принадлежит: Teleplus Healthcare LLC

The present invention provides a system and/or platform that can efficiently monitor/manage patients with sleep disorders. In one embodiment, the system and platform can train and/or certify (or help in training/certifying) service providers/professionals. In one embodiment, the system and platform is integrated with a software or an information system to manage data related to patients. In one embodiment, the system and platform utilizes home sleep test which is more convenient and acceptable. In one embodiment, the system/platform provides the information and knowledge related to a subject's conditions.

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10-01-2019 дата публикации

ENDOTRACHEAL TUBE APPARATUS

Номер: US20190008455A1
Автор: Hacker David C.
Принадлежит: Medtronic Xomed, Inc.

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface and a first location configured to be positioned at the patient's vocal folds. A first electrode is formed on the exterior surface of the endotracheal tube substantially below the first location to receive EMG signals primarily from below the vocal folds. A second electrode is formed on the exterior surface of the endotracheal tube substantially above the first location to receive EMG signals primarily from above the vocal folds. The first and second electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. 1. An apparatus for monitoring EMG signals of a patient's laryngeal muscles , comprising:an endotracheal tube having an exterior surface; anda plurality of conductive electrodes printed on the exterior surface along a posterior side of the endotracheal tube, wherein the conductive electrodes are laterally offset and not substantially longitudinally offset, wherein an anterior side opposite the posterior side is substantially free from conductive electrodes.2. The apparatus of claim 1 , wherein the posterior side of the endotracheal tube is configured to be positioned along a posterior trachea of the patient.3. The apparatus of claim 1 , wherein the anterior side is completely free from conductive electrodes.4. The apparatus of claim 3 , wherein the posterior side of the endotracheal tube is configured to be positioned along a posterior trachea of the patient claim 3 , and wherein the anterior side of the endotracheal tube is configured to be positioned along an anterior trachea of the patient.5. The apparatus of claim 4 , and further comprising a cuff inflating lumen formed in the anterior side of the endotracheal tube.6. The apparatus of claim 1 , wherein the conductive electrodes extend longitudinally along a length of the tube and are spaced ...

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11-01-2018 дата публикации

Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention

Номер: US20180008763A1
Принадлежит: Rheoxtech LLC

A system and methods are described for improving the management of ischemic cardiac tissue during acute coronary syndromes. The system combines a catheter-based sub-system which allows for simultaneous balloon dilation of a coronary artery and infusion of a carefully controlled perfusate during percutaneous coronary intervention. The system allows for modulation of levels of oxygen at the time of percutaneous intervention. In addition, catheters and systems are provided for administration of fluids with modified oxygen content during an intervention that incorporate upstream flow control members to compartmentalize the perfusion of the target coronary artery and the remainder of the heart.

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11-01-2018 дата публикации

SYSTEM AND METHOD FOR CONFIGURING A RULE SET FOR MEDICAL EVENT MANAGEMENT AND RESPONSES

Номер: US20180008772A1
Принадлежит:

A system and method to configure a rule set used in connection with a medical monitoring system for monitoring patients and patient care equipment, especially medication delivery pumps, based on a variety of conditions and parameters associated with monitored biometric information and equipment information and for providing user-defined responses to those conditions and parameters. 1. A method for implementing a medical system algorithm by an authorized medical caregiver , the steps of the method comprising:providing a context free grammar to define the medical system algorithm, the grammar comprising non-terminal parameter symbols and terminal parameter symbols that are configured to be satisfied by a plurality of non-terminal medical system parameters and terminal medical system parameters, respectively, the grammar further comprising non-terminal condition symbols and terminal condition symbols that are configured to be satisfied by a plurality of nonterminal medical system conditions and terminal medical system conditions, respectively, the grammar further comprising a response symbol that is configured to be satisfied by a plurality of medical system responses;receiving a first parameter selection comprising at least of one of the non-terminal parameters or at least one of the terminal parameters, defined by the grammar;receiving a respective first medical system condition selection corresponding to the at least one of the non-terminal parameter symbol or terminal parameter symbol for the selected first parameter selection defined by the grammar;receiving a medical system response selection;generating the medical system algorithm from the first parameter selection, the first medical system condition selection, and the medical system response selection; andstoring the generated medical system algorithm for later use by an automated medical device.2. The method of wherein the first parameter selection comprises at least one of the non-terminal parameter symbols ...

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11-01-2018 дата публикации

PATIENT SPECIFIC AUTO-FLOWRATE CONTROL

Номер: US20180008791A1
Принадлежит:

A respiratory assistance system can provide high flow therapy to patients. The respiratory assistance system can include a patient interface that can deliver a gas flow to a patient and a gas source that can drive the gas flow towards the patient interface at an operating flow rate. The system can include a controller for controlling the operating flow rate of the gas. The controller can apply multiple test flow rate values in a range as the operating flow rate. For each of the test flow rate values, the controller can measure a patient parameter. The controller can determine a new flow rate value based on the measured patient parameters. Patient parameters can include respiration rate, work of breathing, or any other parameters related to the respiratory circuit. 1. A respiratory assistance system for delivering gas to a patient , said respiratory assistance system comprising:a patient interface configured to deliver a gas flow to a patient;a gas source configured to drive the gas flow to the patient interface at an operating flow rate; and apply a plurality of test flow rate values in a range as the operating flow rate;', 'measure at least one patient parameter corresponding to each of the plurality of test flow rate values;', 'determine a new flow rate value based at least in part on the measured at least one patient parameter; and', 'change the operating flow rate to the new flow rate value., 'one or more hardware processors configured to2. The respiratory assistance system of claim 1 , wherein the one or more hardware processors are further configured to determine a rate of change in the measured at least one patient parameter as a function of the change in the applied plurality of test flow rate values.3. The respiratory assistance system of claim 2 , wherein said determining the new flow rate further comprises determining where in the range of the plurality of test flow rate values the rate of change approaches zero.4. The respiratory assistance system of ...

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14-01-2021 дата публикации

ADAPTIVE SYSTEM FOR BLOOD FLUID REMOVAL

Номер: US20210008265A1
Принадлежит:

Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session. 1. A method carried out by a blood fluid removal system , comprising:storing a second data in a most effective to date data set; wherein the second data is data regarding system parameters employed in a first blood fluid removal session of a patient; and wherein a first data is data regarding the patient, the first data including one or more of a physiological parameter and time since last blood fluid removal session prior to the first blood fluid removal session of the patient; wherein at least one physiological parameter is measured in a dialysate;storing the second data in a least effective to date data set;determining whether at least one physiological parameter in a third data is closer to a target value than the first data; and replacing the data in the most effective to date data set with a fourth data if the third data is closer to the target value than the first data;wherein the third data is data regarding the patient, the data including one or more of a physiological parameter and time since last blood fluid removal session prior to a second blood fluid removal session of the patient; wherein at least one physiological parameter is measured in a dialysate; and wherein the fourth data is data regarding system parameters employed in the second blood fluid removal session of the patient;determining whether at least one physiological parameter in the third data is further from a target value than the first data; and replacing the data ...

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14-01-2021 дата публикации

Infusion Unit

Номер: US20210008281A1
Автор: Aamir Zain Jamal
Принадлежит: Individual

Improvements in an infusion unit are disclosed. The infusion unit is a portable pump that can be used with patient that have wrist access or decubital PICC/MID-LINES without the risk of line accidently getting pulled. The infusion unit is in the shape of a conveniently shell that has an appearance of an arm cast. There are no hoses that extend beyond the body of the infusion unit and any vein penetration is completely covered under the body of the infusion unit. The secure enclosed unit prevents unauthorized tampering and entry into the unit. The medication dosing can be remotely monitored, fusion resumed, changed by nursing and the patient. The infusion unit has a wireless connection to a network to adjust medication and monitor vital signs, namely heart rate, O2 level and blood pressure that can be monitored and recorded for review.

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14-01-2021 дата публикации

SLEEP PARALYSIS DETECTION DEVICE WITH EXTERNAL STIMULATION

Номер: US20210008329A1
Принадлежит:

The present invention relates to a device for providing an intervention for users who suffer from sleep paralysis. More specifically, the present invention illustrates a wearable device that measures the user's heart rate while they sleep. If the heart rate rises above a pre-set threshold level, then the device activates an element that exerts an external stimulus on the user causing the user to wake or providing a focal point for the user to overcome the sleep paralysis. 1. An apparatus comprising:a biometric sensor; andan element as a means for exerting a stimulus on the patient.2. The apparatus as in claim 1 , wherein the biometric sensor is a heart rate monitor.3. The apparatus as in claim 1 , wherein the external stimulus is an auditory stimulus claim 1 , such as noise exerted from a speaker.4. The apparatus as in claim 1 , wherein the element that exerts the stimulus is a rumble pack.5. The apparatus as in claim 4 , wherein the rumble pack is enclosed in a wearable element that is worn on the patient's wrist.6. The apparatus as in claim 5 , wherein the wearable element is formed of a bonded polymer substance claim 5 , such as silicone.7. A wearable apparatus comprising:a wearable element formed of a flexible material;a biometric sensor, wherein the biometric sensor is mounted on the wearable element;an element configured to induce an external stimulus mounted on the wearable element.8. The wearable apparatus as in claim 7 , wherein the biometric sensor is a heart rate monitor.9. The wearable apparatus as in claim 7 , wherein the wearable element is a wrist band.10. The wearable apparatus as in claim 9 , wherein in the wrist band is formed of a bonded polymer substance claim 9 , such as silicone.11. The wearable apparatus as in claim 7 , wherein the element for inducing the external stimulus is a rumble pack.12. The wearable apparatus as in claim 7 , where in the element for inducing the external stimulus is a speaker.13. The wearable apparatus as in claim 7 , ...

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27-01-2022 дата публикации

Method and apparatus for continuous management of airway pressure for detection and/or prediction of respiratory failure

Номер: US20220023561A1
Принадлежит: Novaresp Technologies Inc

Various embodiments are described herein for a controller for controlling the operation of a breathing assistance device that provides breathing assistance to a user. The controller comprises a processor that generates a respiratory index value that is determined during a current monitoring time period to detect a respiratory failure, or predict the respiratory failure when at least one PSG signal is measured. The respiratory index value is compared to a threshold to determine if the control signal needs to be updated to reduce or eliminate respiratory failure that the user is currently experiencing or to prevent a predicted respiratory failure from occurring.

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27-01-2022 дата публикации

Humidifier for respiratory apparatus

Номер: US20220023578A1
Принадлежит: ResMed Pty Ltd

A heated conduit is configured to be connected to and receive pressurized breathable gas from a respiratory unit. The heated conduit includes a first cuff configured to be attached to the respiratory unit, the first cuff comprising a tubular air inlet portion that is configured to receive the pressurized breathable gas and an electrical connector portion that is adjacent to the tubular air inlet portion and comprises three electrical terminals. The three electrical terminals are configured to engage an electrical connector of the respiratory unit. A grouping of wires are supported within a helical rib of a flexible tube portion. The grouping of wires includes a pair of heating wires configured to generate heat and a signal wire configured to carry the signal that is output by a sensing device. Each of the heating wires and the signal wire is connected to a corresponding one of the three electrical terminals of the electrical connector portion of the first cuff.

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14-01-2021 дата публикации

Girth adjustable device

Номер: US20210008357A1
Принадлежит:

A girth adjustable device for dilation and stretch of body orifices for medical applications, massage, body orifice improvement and activities pleasurable to the body, that can repeatedly, gradually increase and decrease a uniform and sustainable pressure against the entire lateral surface area of body orifices. The girth adjustable device comprises at least one controller, a housing, at least one threaded shaft, at least one module, a plurality of shaft members and at least one sheath. The part of the girth adjustable device that has to be inserted into body orifices is the shaft. In a body orifice, the user increases and decreases the girth size of the shaft via the controller. 1. A girth adjustable device comprising:a. at least one controller having a first end, and a second end;b. at least one threaded shaft having a first end, a middle section, a second end, and a longitudinal axis, wherein said first end of said threaded shaft is connected to said second end of said controller;c. a housing having a controller first end, a shaft member second end having a plurality of shaft member grooves and a plurality of shaft member protrusions, and a non-threaded canal, wherein said non-threaded canal receives said first end of said threaded shaft, wherein said housing encloses at least said second end of said controller and said first end of said threaded shaft;d. at least one module having at least one conical section with a slant height, at least one anti-rotation connector selected from a group consisting of: a linear anti-rotation connector, a capital letter T shape anti-rotation connector, and an inclined capital letter T shape anti-rotation connector, and a canal selected from a group consisting of: a threaded canal, a threaded canal having at least one fastener cavity, and a non-threaded canal having at least one fastener cavity, wherein said canal receives said threaded shaft;e. a plurality of shaft members having a first end having at least one housing groove, a ...

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09-01-2020 дата публикации

FIELD UPDATE OF AN AMBULATORY INFUSION PUMP SYSTEM

Номер: US20200009319A1
Автор: Ludolph Don
Принадлежит:

Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described. 120-. (canceled)21. A method for remotely downloading software for operating an ambulatory infusion pump , the method comprising:receiving a notification that a software download is available for software for operating an ambulatory infusion pump from a source of the software downloadreceiving verification information from the source of the software download;verifying that a source of the software download is a qualified source based on the verification information;confirming a compatibility of the software download with the ambulatory infusion pump;receiving the software download from the qualified source; anddownloading the software for operating the ambulatory infusion pump only if the source of the software download is a qualified source and if the ambulatory infusion pump is compatible with the software download.22. The method of claim 21 , wherein receiving verification information from the source of the software download includes receiving a unique identifier for the source of the software download.23. The method of claim 22 , wherein the unique identifier for the source of the software download includes a password.24. The method of claim 22 , wherein the unique identifier for the source of the software download includes a certificate.25. The method of claim 21 , further comprising conducting one or more interactive verification tests prior to installing the software download.26. The method of claim 25 , wherein the one or more interactive verification tests include tests to verify proximity to the source of the software download claim 25 , the willingness of the user to initiate the software download claim 25 , or both.27. The method ...

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09-01-2020 дата публикации

Field update of an ambulatory infusion pump system

Номер: US20200009320A1
Автор: Don Ludolph
Принадлежит: Tandem Diabetes Care Inc

Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described.

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08-01-2015 дата публикации

SENSOR FOR DETERMINING CONCENTRATION OF GAS

Номер: US20150011852A1
Принадлежит:

An optical sensor unit () for measuring a concentration of a gas is provided, comprising at least one sensing layer () adapted to be irradiated with a predetermined radiation; at least one gas-permeable layer () adjacent to one side of the at least one sensing layer () and adapted to pass gas which concentration is to be measured through the gas-permeable layer () towards the sensing layer (); a removable protective layer () covering at least the gas-permeable layer () and adapted to be removed before use of the optical sensor unit (), wherein the optical sensor unit () is adapted to measure an optical response of the at least one sensing layer (), which optical response depends on the concentration of the gas. 1. Optical sensor unit for measuring a concentration of a gas , comprising:at least one sensing layer adapted to be irradiated with a predetermined radiation;at least one gas-permeable layer adjacent to one side of the at least one sensing layer and adapted to pass gas which concentration is to be measured through the gas-permeable layer towards the sensing layer;a removable protective layer covering at least the gas-permeable layer and adapted to be removed before use of the optical sensor unit, wherein the optical sensor unit is adapted to measure an optical response of the at least one sensing layer, which optical response depends on the concentration of the gas.2. Optical sensor unit of claim 1 , further comprising a contact medium interposed at least between the gas-permeable layer and the removable protective layer claim 1 , the contact medium being a gel or a liquid claim 1 , wherein the contact medium is adapted to control the water content of the at least one gas-permeable layer and/or the at least one sensing layer.3. Optical sensor unit according to claim 1 , further comprising a second gas-permeable layer interposed between the contact medium and the removable protective layer.4. Optical sensor unit according to claim 1 , further comprising a ...

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19-01-2017 дата публикации

SYSTEM AND METHOD FOR A DRUG DELIVERY AND BIOSENSOR PATCH

Номер: US20170014572A1
Принадлежит:

An integrated drug delivery and biosensor (IDDB) system is implemented on a patch or arm band. The drug delivery system includes needles adapted to pierce the skin and direct injection of a predetermined dosage of medication through the needles into the epidermis of the skin of a patient. The integrated biosensor monitors absorption of the medication into the epidermis of the skin of the patient and may also monitor concentration of the medication or other relevant substances in arterial blood flow of the patient. The integrated biosensor may also monitor a patient's vitals in response to the medication. The integrated biosensor may then alter dosage or frequency of administration of dosages or even halt a dosage of medication in response to the patient's vitals or absorption of the medication. 1. An integrated drug delivery and biosensor (IDDB) system , comprising:a patch configured for attaching to a patient;a drug delivery system coupled to the patch, wherein the drug delivery system is configured to administer a dosage of medication at an administration rate to the patient; monitor biosensor data of the patient, wherein the biosensor data includes one or more of: respiratory rate, heart rate or blood pressure;', 'monitor absorption rate of the medication into one or more of: surrounding tissue or arterial blood flow; and', 'monitor concentration of a substance in one or more of: surrounding tissue or arterial blood flow;, 'a biosensor system coupled to the patch, wherein the biosensor system is configured towherein the drug delivery system is configured to alter at least one of the dosage of the medication or the administration rate of the medication in response to the biosensor data.2. The IDDB system of claim 1 , wherein the drug delivery system includes one or more needles and is configured to administer the dosage of the medication at the administration rate through the one or more needles into at least an upper epidermal layer of the skin.3. The IDDB system ...

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19-01-2017 дата публикации

Pressure range adjustment for respiratory therapy device

Номер: US20170014587A1
Принадлежит: Fisher and Paykel Healthcare Ltd

An automatic positive airway pressure (AutoPAP) therapy device can be configured such that the minimum and/or maximum pressures deliverable by the device can automatically change. The minimum and/or maximum pressures can change as a function of pressures delivered over the course of the current therapy session and/or over the course of prior therapy sessions. The minimum and/or maximum pressures can also change as a function of the presence, absence, type, severity, or length of sleep disordered breathing events (SDBE) detected by the device over the course of the current therapy session and/or over the course of prior therapy sessions.

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19-01-2017 дата публикации

REDUCING HYPERCAPNIC RESPIRATORY FAILURE DURING MECHANICAL VENTILATION

Номер: US20170014588A1
Принадлежит:

Systems and methods provide respiratory therapy to a subject through a pressurized flow of breathable gas. Timing and other characteristics of pressure and flow levels provided during inhalations and exhalations are adjusted in order to increase the volumetric rate of expulsion of CO2. 1. A system configured to provide mechanical ventilation to a subject , the system comprising:(a) a pressure generator configured to provide a pressurized flow of breathable gas at a pressure level to an airway of a subject;(b) one or more sensors configured to generate output signals conveying information related to breathing of the subject, wherein the breathing includes inhalations and exhalations; and (1) determine one or more phase timing parameters related to the breathing of the subject based on the generated output signals;', '(2) determine one or more breathing parameters of the subject based on the generated output signals, wherein the one or more breathing parameters indicate one or more of lung volume, tidal volume, and/or flow rate of the breathing of the subject;', '(3) determine, during exhalations, whether the subject has completed a particular exhalation based on the one or more breathing parameters; and, '(c) one or more physical processors configured to(4) control the pressurized flow in accordance with a respiratory therapy regimen such that the pressure level of the pressurized flow corresponds to an inspiratory positive airway pressure level during inhalations and to an expiratory positive airway pressure level during exhalations, wherein the control of the pressurized flow during a particular inhalation is based on the one or more phase timing parameters and the determination whether the subject has completed the particular exhalation, and wherein the particular inhalation is subsequent to the particular exhalation.2. The system of claim 1 , wherein inhalations have inspiratory periods claim 1 , wherein control of the pressurized flow during inhalations includes ...

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18-01-2018 дата публикации

Vaginal Drug Delivery Device

Номер: US20180015270A1
Принадлежит:

The present invention relates to a vaginal drug delivery device configured for placement within the vagina, comprising a housing, at least one reservoir comprising a biologically active compound that is not normally administered via the vagina and means for the controlled release of the compound from the reservoir into the vagina. Suitably the vaginal device further comprising means for gathering physiological data of a person carrying the device in her vagina. Alternatively, the vaginal drug delivery device configured for placement within the vagina, comprises a housing and means for gathering physiological data of a person carrying the device in her vagina. The invention further relates to oxybutynin for use in the treatment of urinary and bladder problems, in particular urge incontinence, wherein oxybutynin is administered to a person in need of treatment by means of the vaginal device, and to other therapeutic compounds that are administered via the vaginal device for use in their corresponding indications. 1. A vaginal drug delivery device configured for placement within the vagina , comprising a housing , at least one reservoir comprising a biologically active compound that is not normally administered via the vagina and means for the controlled release of the compound from the reservoir into the vagina.2. The vaginal device as claimed in claim 1 , further comprising means for gathering physiological data of a person carrying the device in her vagina.3. The vaginal device as claimed in claim 1 , wherein the means for the controlled release of the compound from the reservoir are configured to act in response to physiological data of a person carrying the device in her vagina.4. The vaginal device as claimed in claim 1 , wherein the means for the controlled release of the compound from the reservoir are operated remotely claim 1 , in particular by the person carrying the device in her vagina claim 1 , a nurse or a physician.5. The vaginal device as claimed in ...

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21-01-2016 дата публикации

Method and System of Utilizing ECG Signal for Central Venous Catheter Tip Positioning

Номер: US20160015933A1
Автор: Bukhman Vladislav
Принадлежит:

Disclosed herein are a method and a medical system for utilizing of a intravascular ECG signal for central venous catheter placement. The medical system is capable of detecting the position of a catheter tip and assessing its location relative to the cavoatrial junction. The detection and assessment are performed by a multiscale analysis of the complexity of the intravascular signal data points.

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15-01-2015 дата публикации

STIMULATION OF PENIS ERECTION

Номер: US20150018609A1
Автор: Forsell Peter
Принадлежит:

A penis erection stimulation system comprises a fully implantable drug delivery device for delivering a drug in relation to a penis to achieve erection of the penis. The drug delivery device may comprise a catheter adapted to be implanted in the corpora cavernosa of a penis or in close proximity thereto in order to deliver drugs through said catheter. Alternatively, one or more infusion needles may be disposed within and implanted along with one or more housings adjacent the patient's left and right corpora cavernosa. A reservoir and a pump may also be implanted inside the patient's body to supply the infusion needle with infusion liquid. A drive unit also adapted for implantation inside the patient's body is arranged for advancing and retracting the tip end of the infusion needle such that it penetrates the housing at least in two different penetration areas either simultaneously or in immediate time succession, thereby injecting drugs along with the infusion liquid into the patient's body for stimulating penis erection. 1. A method of implanting a penis erection stimulation system , comprising a fully implantable drug delivery device adapted to deliver a drug in relation to a penis to achieve erection of the penis , wherein the drug delivery device comprises at least one infusion needle adapted to be placed outside a left or a right corpus cavernosum in close proximity thereto , wherein the fully implantable drug delivery device is adapted to be noninvasively powered , when implanted , wherein the infusion needle is adapted to be advanced into and retracted from , as well as deliver at least one drug when advanced into , at least one of; the left or right corpus cavernosum , one or two of deep arteries thereof , muscle tissue regulating blood flow through the right , left or both corpus cavernosum , and tissue in close proximity to the left , right or both corpus cavernosum , and whenever the needle is or has been advanced , when the drug delivery device is ...

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21-01-2021 дата публикации

IMAGE-GUIDED LUMBAR PUNCTURE ASPIRATION AND INJECTOR SYSTEM AND METHOD

Номер: US20210016000A1
Автор: Anand PJ, Singh Deep Arjun
Принадлежит:

An image-guided lumbar puncture aspiration and injector system. The system includes an auto-injection device having a housing, at least one syringe having a fluid, a controller, a processor, a memory, and a display. An imaging device is communicatively coupled to the auto-injection device and captures images of a lumbar puncture area of a patient to be displayed on the display of the auto-injection device, helping identify a location for a lumbar puncture procedure. A needle assembly is coupled to the at least one syringe of the auto-injection device. An outer needle is adapted to be inserted into a location of the lumbar puncture area identified by the imaging device, and an inner needle is adapted to be inserted into the dura of the patient. The outer sheath needle protects the inner needle from contaminants. The controller operates the auto-injection device based on a programmed infusion and aspiration profile. 1. An image-guided aspiration and injector system , comprising:an auto-injection device having a housing, at least one syringe carried by the housing and having a fluid, and a controller disposed within the housing,;an imaging device coupled to the auto-injection device and adapted to capture at least one image of a lumbar puncture area of a patient; anda needle assembly coupled to the at least one syringe of the auto-injection device, the needle assembly including an outer needle adapted to be inserted into a location of the lumbar puncture area of the patient identified by the imaging device, and an inner needle disposed within the outer needle and adapted to be inserted into a dura of the patient,wherein the controller is configured to retrieve an infusion and aspiration profile, the infusion and aspiration profile comprising an infusion and aspiration protocol for the at least one syringe, the controller configured to operate the auto-injection device based on the infusion and aspiration protocol.2. The system of claim 1 , wherein the lumbar puncture ...

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21-01-2021 дата публикации

System, method and article for controlling the dispensing of insulin

Номер: US20210016001A1
Принадлежит: Dexcom Inc, Dose Safety

An integrated circuit includes circuitry to control a process. The process includes adjusting fuzzy-logic control parameters based on received and retrieved blood glucose-related data, predicting blood glucose levels based on the received blood-glucose-related data, and generating control signals to control dispensing of insulin based on the received blood glucose-related data and the fuzzy-logic control parameters. The process may include predicting blood glucose levels based on the retrieved blood glucose-related data. The process may include transitioning between a post-meal correction protocol and a fasting protocol. The process may include transitioning from a post-meal correction protocol to a fasting protocol when a fasting criteria is satisfied.

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21-01-2021 дата публикации

ESOPHAGEAL PRESSURE CLINICAL DECISION SUPPORT SYSTEM

Номер: US20210016035A1
Автор: EULIANO, II Neil Russell
Принадлежит:

A novel clinical decision support system (CDS) helps the clinician setup, maintain, and interpret aesophageal pressure measurement. The esophageal pressure CDS (Pes CDS) would remind the clinician to do an occlusion test whenever the balloon is first inserted or changes dramatically. It could monitor the occlusion test and provide feedback on the performance and success of the occlusion test. Changes in the patient or monitored data can be tracked by looking for changes in the balloon baseline pressure, changes in the amplitude of the pressure waveform, or changes in the pattern of the Pes waveform. Having information from the ventilator will further increase the ability of the system to determine when Pes is changing unexpectedly. 1. A system to improve operation of a ventilator comprising:one or more sensors to provide measurement data for each of esophageal pressure data, airway pressure data, and airway flow data from a patient being ventilated; anda processor electronically coupled to the sensors and receiving the measurement data therefrom, the processor continuously compares the esophageal pressure data with changes to one or more of airway pressure data and air flow data to determine an accuracy of the esophageal pressure data.2. The system of claim 1 , wherein the accuracy of the esophageal pressure data is determined by comparing the airway pressure data to the esophageal pressure data during one or more of a trigger portion of a breath claim 1 , an end exhalation portion of a breath claim 1 , or an end expiratory pause of a breath from the patient being ventilated.3. The system of claim 2 , wherein the comparing occurs over multiple breaths from the patient being ventilated and the processor further determines a trend that is included in the accuracy of the esophageal pressure data.4. The system of claim 1 , further comprising:a display for indicating a status of the patient or system using the esophageal pressure data; andwherein status on the display is ...

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21-01-2021 дата публикации

IMPLANTABLE VENOUS ACCESS PORT WITH REMOTE PHYSIOLOGICAL MONITORING CAPABILITIES

Номер: US20210016074A1
Принадлежит:

An apparatus for an implantable venous access port with remote physiological monitoring capabilities is disclosed. A system and method also perform the functions of the apparatus. In one embodiment the apparatus includes a chemotherapy access port, a plurality of sensors integrated with the chemotherapy access port, where the plurality of sensors determine one or more chemotherapy-related physiological indicators and the one or more physiological indicators include at least parameters selected from red blood cell count, white blood cell count, platelets, and/or ejection fraction. The apparatus includes a communications module integrated with the chemotherapy access port, where the communications module is configured to communicate the one or more chemotherapy-related physiological indicators to a computing device. 1. An apparatus , comprising:a chemotherapy access port;a plurality of sensors integrated with the chemotherapy access port, the plurality of sensors configured to determine one or more chemotherapy-related physiological indicators, the one or more physiological indicators comprising at least parameters selected from red blood cell count, white blood cell count, platelets, and/or ejection fraction; anda communications module integrated with the chemotherapy access port, the communications module configured to communicate the one or more chemotherapy-related physiological indicators to a computing device.2. The apparatus of claim 1 , wherein the plurality of sensors comprises a blood cell counting sensor for determining the red blood cell count claim 1 , the white blood cell count claim 1 , and/or the platelet count.3. The apparatus of claim 2 , wherein the blood cell counting sensor comprises an autofluorescence sensor configured to perform an in-vivo count of red blood cells claim 2 , white blood cells claim 2 , and platelets.4. The apparatus of claim 3 , wherein the autofluorescence sensor comprises:a source configured to generate and emit excitation ...

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22-01-2015 дата публикации

BREATHABLE GAS APPARATUS WITH HUMIDIFIER

Номер: US20150020805A1
Принадлежит:

A flow generator and humidifier construction is described, including a flow generator construction adapted to reduce noise output compared to known flow generators of comparable size. The flow generator includes a chassis forming first and second muffler volumes and a venturi-shaped connection portion, and a metal/polymer composite material blower enclosure which suppresses noise from the blower. The flow generator may be programmed to include a reminder system including a menu from which the user may request a reminder to take specific action, e.g., replace a component, call a physician, and/or enter patient data card, etc. 1. A humidifier for delivering humidified breathable gas to a patient , the humidifier comprising:a base unit configured to attach to and detach from a flow generator, the base unit comprising an elastomer airway seal; anda water container with an inlet and an outlet, the water container being attachable to and detachable from the base unit,wherein the inlet of the water container is configured to create a sealed air path with the elastomer airway seal upon attaching the water container to the base unit.2. A humidifier according to claim 1 , wherein the sealed air path extends from an outlet of the flow generator to a headspace of the water container.3. A humidifier according to claim 1 , wherein the base unit comprises a front cover and a rear cover and the elastomer airway seal fits between the front and rear covers.4. A humidifier according to claim 3 , wherein the front cover includes an aperture and the elastomer airway seal comprises a peripheral seal portion configured to extend about a periphery of the aperture in the front cover.5. A humidifier according to claim 4 , wherein the rear cover includes an air port configured to mate with an outlet of the flow generator.6. A humidifier according to claim 5 , wherein the elastomer airway seal connects the air port to the aperture in the front cover.7. A humidifier according to claim 1 , ...

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28-01-2016 дата публикации

Vaginal Drug Delivery and/or Diagnostic System

Номер: US20160022198A1
Принадлежит:

The present invention relates to a vaginal drug delivery and/or diagnostic system, which is connected to a positioning member configured for placement within the vagina. The system comprises an electronic capsule comprising a drug reservoir and means for dispensing the drug from the reservoir into the vagina. The positioning member is for example eight-shaped, pear-shaped or dolphin-shaped and is preferably provided with friction-enhancing means to keep the device in place. The system is particularly useful for systemic administration of drugs and hormones. 1. A vaginal drug delivery and/or diagnostic system , comprising an electronic capsule , which is connected to a positioning member configured for placement within the vagina.2. The vaginal drug delivery and/or diagnostic system as claimed in claim 1 , wherein the electronic capsule comprises one or more components selected from drug reservoirs claim 1 , diagnostic means and means for dispensing the drug from a reservoir into the vagina.3. The vaginal drug delivery and/or diagnostic system as claimed in claim 1 , wherein the positioning member has a substantially closed peripheral shape.4. The vaginal drug delivery and/or diagnostic system as claimed in claim 3 , wherein the substantially closed peripheral shape is formed by two parts claim 3 , one being larger than the other.5. The vaginal drug delivery and/or diagnostic system as claimed in claim 4 , wherein each part defines a plane claim 4 , the plane defined by the first part being offset with respect to the plane defined by the second part.6. The vaginal drug delivery and/or diagnostic system as claimed in claim 1 , wherein the positioning member is eight-shaped.7. The vaginal drug delivery and/or diagnostic system as claimed in claim 6 , wherein at least one capsule is located in between the two parts.8. The vaginal drug delivery and/or diagnostic system as claimed in claim 1 , wherein the positioning member is pear-shaped.9. The vaginal drug delivery and/ ...

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26-01-2017 дата публикации

BIOLOGICAL INFORMATION MEASURING DEVICE AND DRUG SOLUTION SUPPLY DEVICE

Номер: US20170020423A1
Принадлежит:

An information measuring device includes a detection film placed on the surface of a first needle section, an electrically conductive second needle section, and an electric current detection circuit which detects an electric current between the detection film and the second needle section. The major axis of the first needle section is 0.1 mm or more and 0.3 mm or less. 1. A biological information measuring device , comprising:a first sensor electrode which is inserted into a body by piercing the skin surface;a second sensor electrode which is inserted into the body by piercing the skin surface; andan electric current detection section which detects an electric current between the first sensor electrode and the second sensor electrode, whereinthe device measures in-vivo information.2. The biological information measuring device according to claim 1 , wherein the major axis of the first sensor electrode is 0.1 mm or more and 0.3 mm or less.3. The biological information measuring device according to claim 1 , wherein the straight-line distance between the first sensor electrode and the second sensor electrode is 1 mm or more and 50 mm or less.4. The biological information measuring device according to claim 1 , wherein the first sensor electrode is provided with a sensing detection layer.5. The biological information measuring device according to claim 1 , whereinthe in-vivo information is information associated with glucose,the first sensor electrode is a working electrode which is provided with an enzyme layer as the sensing detection layer, andthe second sensor electrode is a counter electrode which receives an electric current generated in the first sensor electrode.6. The biological information measuring device according to claim 1 , whereinthe biological information measuring device further comprises a reference electrode which is used for detecting a resistance to an electric current flowing through the first sensor electrode, andthe straight-line distance ...

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26-01-2017 дата публикации

ACTUATED EXTRA-VENOUS VALVE

Номер: US20170020671A1
Принадлежит: Boston Scientific Scimed Inc.

An extravenous valve may include a constricting member configured to surround a body lumen or blood vessel and actuate between a lumen or vessel-occluding configuration and a non-lumen or non-vessel-occluding, configuration, the constricting member including a base material and a shape memory material coupled to the base material, a power source in communication with the constricting member, and a controller configured to receive bio-feedback from a patient. The controller may reversibly actuate the constricting member between the lumen or vessel-occluding configuration and the non-lumen or non-vessel-occluding configuration in response to the bio-feedback. The constricting member may be sized and configured to be delivered to the treatment location through the body lumen or blood vessel. 1. An extravenous valve , comprising:a constricting member configured to surround a blood vessel and actuate between a vessel-occluding configuration and a non-vessel-occluding configuration, the constricting member including a base material and a shape memory material coupled to the base material;a power source in communication with the constricting member; anda controller configured to receive bio-feedback from a patient;wherein the controller reversibly actuates the constricting member between the vessel-occluding configuration and the non-vessel-occluding configuration in response to the bio-feedback.2. The extravenous valve of claim 1 , wherein the controller continuously actuates the constricting member back and forth between the vessel-occluding configuration and the non-vessel-occluding configuration.3. The extravenous valve of claim 1 , wherein the base material is a polymer.4. The extravenous valve of claim 1 , wherein the shape memory material is at least partially embedded within the base material.5. The extravenous valve of claim 1 , wherein the power source communicates with the constricting member via one or more wires.6. The extravenous valve of claim 1 , wherein ...

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26-01-2017 дата публикации

ORAL APPLIANCE

Номер: US20170020715A1
Принадлежит:

An integrated oral appliance for treating breathing obstruction, snoring and restriction of the upper airway during sleep with a tongue restraint. Oral appliances of the invention may include an oral cavity engagement device including one or more trays, a tongue restraint with a tongue contact portion, a spring force element operatively coupled between the at least one tray and the tongue restraint, wherein the spring force element is adjustable anteriorly and posteriorly relative to the tray(s), and an air conduit inside the tongue restraint with a front vent of the air conduit extending beyond an anterior end of the tray(s) and a rear opening of the air conduit at a posterior end of the of the oral cavity engagement device configured to extend to a posterior surface of a tongue. 1. An oral appliance comprising:an oral cavity engagement device including at least one tray;a tongue restraint including a tongue contact portion;an element providing a spring force operatively coupled to the at least one tray and to the tongue restraint, wherein the element providing a spring force and the tongue contact portion are adjustable anteriorly and posteriorly relative to the at least one tray; andan air conduit configured with a front vent allowing air at atmospheric pressure to enter the air conduit from beyond an anterior end of the at least one tray, and a rear opening of the air conduit at a posterior end of the of the oral cavity engagement device configured to extend to a posterior surface of a tongue.2. The oral appliance of claim 1 , wherein the element providing a spring force applies a spring force to the tongue restraint.3. The oral appliance of claim 1 , wherein the tongue contact portion is rigid and angled downward in relation to the at least one tray.4. The oral appliance of claim 1 , wherein the tongue contact portion includes a slip-resistant surface selected from the group consisting of a surface including projections claim 1 , a surface including bristles ...

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26-01-2017 дата публикации

Automated therapy system and method

Номер: US20170020724A1
Принадлежит: TheraNova LLC

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

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28-01-2016 дата публикации

THORACIC AORTA VENTRICULAR ASSIST SYSTEM

Номер: US20160022888A1
Принадлежит:

An implantable heart assist system, includes a pumping chamber formed of a flexible material and being adapted to be placed in fluid connection with the aorta and a pump system comprising a first rigid member, a second rigid member spaced from the first rigid member so that at least a portion of the pumping chamber may be positioned between the first rigid member and the second rigid member, a drive system comprising a motor, an extending member comprising a threaded section operatively connecting the first rigid member and the second rigid member and a nut in operative connection with the threaded section. The motor is adapted to rotate either the extending member or the nut relative to the other to convert rotary motion of the motor to linear motion to cause the second rigid member to move toward the first rigid member or away from the first rigid member. The heart assist system further includes a controller or a control system in operative connection with the drive system and controlling the motor. Movement of the second rigid member toward the first rigid member results in compression of the pumping chamber, and movement of the second rigid member away from the first rigid member causes expansion of the pumping chamber. 1. An implantable heart assist system , comprising:a pumping chamber formed of a flexible material and being adapted to be placed in fluid connection with the thoracic aorta; anda pump system comprising a first rigid member, a second rigid member spaced from the first rigid member so that at least a portion of the pumping chamber may be positioned between the first rigid member and the second rigid member, a drive system comprising a motor and an actuator mechanism to convert rotary motion of the motor to linear motion to cause the second rigid member to move toward the first rigid member or away from the first rigid member, and a controller in operative connection with the drive system and controlling the motor, wherein movement of the second ...

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28-01-2016 дата публикации

SYSTEM, METHOD AND ARTICLE FOR CONTROLLING THE DISPENSING OF INSULIN

Номер: US20160022904A1
Принадлежит:

A system and method for automatically adjusting parameters for predicting blood glucose levels and/or controlling the dispensing of insulin. In one embodiment, the system is a stand-alone system. In one embodiment, the system is part of a system for controlling the dispensing of insulin. 1131-. (canceled)132. An integrated circuit , comprising:one or more memories; and adjusts fuzzy-logic control parameters based on received and retrieved blood glucose-related data; and', 'generates a control signal to control dispensing of insulin based on the received blood glucose-related data and the fuzzy-logic control parameters., 'circuitry coupled to the one or more memories, wherein the circuitry, in operation133. The integrated circuit of wherein the circuitry claim 132 , in operation claim 132 , predicts blood glucose levels based on the received blood glucose-related data.134. The integrated circuit of wherein the circuitry claim 133 , in operation claim 133 , predicts blood glucose levels based on the retrieved blood glucose-related data.135. The integrated circuit of wherein the circuitry claim 132 , in operation claim 132 , selectively transitions between a post-meal correction protocol and a fasting protocol.136. The integrated circuit of wherein the circuitry claim 132 , in operation claim 132 , transitions from a post-meal correction protocol to a fasting protocol when a fasting criteria is satisfied.137. The integrated circuit of wherein the circuitry claim 132 , in operation claim 132 , transitions from a fasting protocol to a post-meal correction protocol when a prandial event is detected.138. The integrated circuit of wherein the circuitry claim 132 , in operation claim 132 , transitions from a fasting protocol to a user-input protocol when a prandial event is detected.139. The integrated circuit of wherein the fuzzy-logic control parameters comprise fuzzy-logic multipliers.140. The integrated circuit of wherein the predicting blood glucose levels comprises ...

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28-01-2016 дата публикации

DEVICE, SYSTEM AND METHOD FOR SUBCUTANEOUS DRUG DELIVERY

Номер: US20160022905A1
Автор: Bitton Gabriel, Nagar Ron
Принадлежит: Insuline Medical Ltd

Embodiments of the present disclosure present systems, methods and devices relate to delivering a drug subcutaneously to a patient. For example, a subcutaneous drug delivery device for use in delivering a drug subcutaneously to a patient can include a needle or cannula configured for delivery of a drug from a drug reservoir to a subcutaneous tissue of a patient. 163-. (canceled)64. A subcutaneous drug delivery device for use in delivering a drug subcutaneously to a patient , the device comprising:a needle or cannula configured for delivery of a drug from a drug reservoir to a subcutaneous tissue of a patient;a treatment element configured to modify delivery of the drug into the circulatory system of the patient by application of a treatment via a surface of skin based on at least one property of the drug and/or at least one property of a drug depot, wherein the drug depot comprises an area of tissue surrounding the needle or cannula;at least one sensor configured to generate at least one signal determinative of the at least one property and generate a sensor signal representative thereof; anda controller to receive the sensor signal and configure treatment by the treatment element based on the at least one property, wherein the at least one property of the drug comprises at least one of a pharmacokinetic and pharmacodynamics profile of the drug.65. The device of claim 64 , wherein the application of treatment includes at least one of the following: heating claim 64 , cooling claim 64 , mechanical vibrations claim 64 , suction claim 64 , massaging claim 64 , acoustic stimulation claim 64 , electromagnetic radiation claim 64 , magnetic stimulation claim 64 , radio frequency irradiation claim 64 , microwave irradiation claim 64 , electrical stimulation claim 64 , Transcutaneous Electrical Nerve Stimulation (TENS) claim 64 , an additional substance claim 64 , drugs claim 64 , medicament claim 64 , chemicals claim 64 , biologically active bacteria claim 64 , biologically ...

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28-01-2016 дата публикации

INTEGRATED ANALYTE SENSOR AND INFUSION DEVICE AND METHODS THEREFOR

Номер: US20160022906A1
Автор: Jennewine R. Curtis
Принадлежит:

Method and system for providing an integrated analyte monitoring system and on-body patch pump with multiple cannulas and a sensor combination is provided. 1. An integrated therapy management system , comprising:a first cannula for transcutaneous placement under a skin layer of a patient at a first infusion site for a first time period;a second cannula for transcutaneous placement under the skin layer of the patient at a second infusion site for a second time period; and 'wherein the first cannula and the second cannula are configured to deliver a therapeutic agent to the patient during the predetermined time period.', 'an analyte sensor configured for fluid contact with an analyte of the patient for a predetermined time period;'}2. The system of further including a housing claim 1 , wherein the first cannula claim 1 , the second cannula and the sensor are coupled to the housing.3. The system of further including a housing claim 1 , wherein the first cannula and the sensor are coupled to the housing.4. The system of wherein the second cannula is connected to the housing by an infusion tubing.5. The system of wherein the first infusion site and the second infusion site are separated by a predetermined distance.6. The system of wherein the predetermined time period includes approximately seven days.7. The system of further including a reservoir coupled to the first cannula and the second cannula.8. The system of further including a first reservoir coupled to the first cannula claim 1 , and a second reservoir coupled to the second cannula.9. The system of wherein when the second cannula is transcutaneously positioned claim 1 , the first cannula is withdrawn from the first infusion site.10. The system of wherein the sensor includes an analyte sensor.11. The system of wherein the therapeutic agent includes insulin.12. A method claim 1 , comprising:positioning a portion of a first cannula under the skin of a patient;positioning a portion of a sensor under the skin of the ...

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28-01-2016 дата публикации

Apparatus and Method for Adaptive Closed-loop Control of Oxygen-Hemoglobin Saturation Levels

Номер: US20160022952A1
Автор: Brown Douglas A.
Принадлежит: NAB Medical, Inc.

The present invention is a method, system, and apparatus for providing automated closed-loop control of oxygen-hemoglobin saturation, SO, levels that adapts to the specific, unique, and variable needs of the individual patient in real-time. A method, system, and standalone breathable gas blending apparatus for controlling SOlevels in human patients requiring supplemental oxygen therapy, inclusive of adults, pediatrics, and neonates, are described. 1. A method for adjusting and blending inspired oxygen delivered to a patient in response to a hemoglobin oxygen saturation level measured in the patient , comprising:(a) specifying a target range of hemoglobin oxygen saturation levels through a user interface in communication with a signal and data processor (SDP);(b) specifying an initial inspired oxygen level to be delivered to the patient as determined by the care provider through the user interface;{'sub': p', '2, '(c) measuring a hemoglobin oxygen saturation level of a patient at an SOsensor;'}{'sub': p', '2, '(d) transmitting a signal with a measured hemoglobin oxygen saturation value of the patient from the SOsensor;'}{'sub': p', '2, '(e) receiving the signal from the SOsensor at the SDP;'}(f) comparing the measured hemoglobin oxygen saturation value to at least one preset patient parameter and a target rate of change of the at least one preset patient parameter using the SDP;(g) determining whether the measured hemoglobin oxygen saturation value is within the target range using the SDP;(h) incorporating the difference between the target and measured oxygen hemoglobin values into an adaptive response parameter;(i) computing the hemoglobin oxygen saturation value predicted to occur at the next measurement;(j) comparing the predicted hemoglobin oxygen saturation value to the target value and range, and predicted future values of the patient's hemoglobin saturation level;(k) if it is determined that the predicted hemoglobin oxygen saturation value is outside the ...

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28-01-2016 дата публикации

APPARATUS AND METHODS FOR TREATING INTRACORPOREAL FLUID ACCUMULATION

Номер: US20160022971A1
Принадлежит: Sequana Medical AG

A fluid management system for the treatment of ascites, pleural effusion or pericardial effusion is provided including an implantable device including a pump, control circuitry, battery and transceiver; a charging and communication system configured to periodically charge the battery and communicate with the implantable device to retrieve performance data; and monitoring and control software, suitable for use with conventional personal computers, for configuring and controlling operation of the implantable device and charging and communication system. The implantable device includes a number of features that provide automated movement of fluid to the bladder with reduced risk of clogging, with no patient involvement other than occasional recharging of the battery of the implantable device. The monitoring and control software is available only to the treating physician, such that the physician interacts with the implantable device via the charging and communication system. 1. A fluid management system comprising:an inflow catheter comprising an inlet end and an outlet end;an outflow catheter comprising an inlet end and an outlet end adapted to be positioned in a sink cavity;an implantable pump coupled to the outlet end of the inflow catheter and the inlet end of the outflow catheter, the implantable pump comprising a housing containing a positive displacement gear pump coupled to an electric motor and a controller coupled to a battery, the controller programmed to automatically activate the motor and gear pump to move fluid from the inlet end of the inflow catheter to the sink cavity responsive to operational parameters stored at the controller; anda non-transitory computer readable medium programmed with instructions that, when run on a computer, cause a graphical user interface of the computer to visually display information indicative of status of the implantable pump wirelessly transmitted from the implantable pump, the computer readable medium further configured ...

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26-01-2017 дата публикации

STRAIN GAUGE FOR FLOW ESTIMATION

Номер: US20170021070A1
Автор: Petersen Ethan Falk
Принадлежит:

A pressure differential across a blood pump and/or a flow rate of blood pumped by the blood pump is estimated based at least in part on impeller thrust load. A blood pump for a circulation assist system includes a housing forming a blood flow channel, an impeller, one or more support members coupled to the housing, a sensor, and a controller operatively coupled with the sensor. At least one of the one or more support members react a thrust load applied to the impeller by blood impelled through the blood flow channel by the impeller. The sensor generates output indicative of the magnitude of the thrust load. The controller is configured to process the sensor output to estimate at least one of a pressure differential across the blood pump and a flow rate of blood pumped by the blood pump. 1. A blood pump for a circulation assist system , the blood pump comprising:a housing forming a blood flow channel;an impeller disposed within the blood flow channel;one or more support members coupled to the housing, the one or more support members reacting a thrust load applied to the impeller by blood impelled through the blood flow channel by the impeller;a sensor generating a sensor output indicative of a magnitude of the thrust load reacted by at least one of the one or more support members; and a pressure differential of the blood impelled through the blood flow channel, and', 'a flow rate of blood pumped by the blood pump., 'a controller operatively coupled with the sensor, the controller being configured to process the sensor output to estimate at least one of2. The blood pump of claim 1 , wherein the impeller is supported via one or more support bearings supported by the one or more support members and the thrust load reacted by the one or more support members is applied to at least one of the one or more support members via at least one of the one or more support bearings.3. The blood pump of claim 2 , comprising an inlet stator that includes at least one of the one or ...

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26-01-2017 дата публикации

Heart help device, system, and method

Номер: US20170021073A1
Автор: Peter Forsell
Принадлежит: Individual

An implantable device for improving the pump function of the heart of a human patient by applying an external force on the heart muscle is provided. The device comprises at least one pump device having a pump. The pump comprising: a piston adapted for reciprocating movement, an operating device for operating the piston, a heart contacting organ. The movement of the piston assists the pump function of the heart through said heart contacting organ.

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