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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 10787. Отображено 100.
28-08-2017 дата публикации

Устройство трансдермального местного и/или ингаляционного введения биологически активных веществ (подворотничок)

Номер: RU0000173456U1
Автор: Владимир Витальевич Смирнов, Игорь Григорьевич Логачёв, Сергей Федорович Савенков
Принадлежит: Российская Федерация, от имени которой выступает Министерство обороны Российской Федерации

Полезная модель относится как к средствам гигиены, так и к медицине, а именно к устройствам или приспособлениям для нанесения сред, например, гигиенических, лекарств на кожный покров, а также к простейшим ингаляционным устройствам с активированными или ионизированными газами (парами), получаемыми при испарении с пропитанной определенным составом (гигиеническими, лекарственными препаратами, содержащими органические активные ингредиенты, способные к испарению при соприкосновении с кожей человека) поверхности материала, из которого произведено данное устройство.Предлагаемое техническое решение полностью отменяет процесс пришивания подворотничка, который применяется в различных силовых структурах в полевой форме одежды. Отказ от традиционного использования пришивных подворотничков сократит время замены подворотничка и определенное количество материальных средств для его прикрепления (материал, нитки, иголки). Использование данного технического решения исключит травматизацию пальцев кистей с заносом болезнетворных микроорганизмов и развитием нагноений.Новым является прикрепление липучек к воротнику одежды и к самому устройству, а также пропитка подворотничка, в зависимости от поставленных целей и задач, различными веществами (тонизирующими, успокаивающими, обезболивающими, отпугивающими (репелленты) или их комбинациями). Ц 1 173456 ко РОССИЙСКАЯ ФЕДЕРАЦИЯ 19 11 зе а за г (13 7 ВУ “17345841 (51) МПК ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ Аб1М 3500 (2006.01) (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (21)(22) Заявка: 2016135178, 29.08.2016 (24) Дата начала отсчета срока действия патента: 29.08.2016 Дата регистрации: 28.08.2017 Приоритет(ы): (22) Дата подачи заявки: 29.08.2016 (45) Опубликовано: 28.08.2017 Бюл. № 25 Адрес для переписки: 119160, Москва, начальнику Управления интеллектуальной собственности Министерства, обороны Российской Федерации (72) Автор(ы): Смирнов Владимир Витальевич (КО), Логачёв Игорь Григорьевич (КП), Савенков Сергей Федорович (КП) (73) ...

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Номер записи: 1
16-02-2012 дата публикации

System and methods for the production of personalized drug products

Номер: US20120041778A1
Автор: Daniel L. Kraft
Принадлежит: Individual

A system and method for determining an optimal combination drug product for a particular patient includes a processor that receives patient information and determines an optimal combination drug product based on the received information. A system which can provide information regarding predicted events or pathologies based on received patient information and guidance on subsequent steps to ameliorate, treat or intervent. A drug production device includes a plurality of drug containers, each of which are coupled to a drug dispensing channel. A controller controls the dispensing of drug through each channel, and a combination drug product is produced from the dispensed drugs. A combination drug product includes a plurality of discrete units of a first drug, and a plurality of discrete units of a second drug. A transdermal patch includes a plurality of drug compartments, each containing a quantity of drug product, and a controller for controlling the release of drugs from each compartment. Feedback loop elements can enable iterations to optimized personalized doses.

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Номер записи: 2
15-03-2012 дата публикации

Seal-less device for dispensing microliter quantities of a material into a site

Номер: US20120065666A1
Автор: Grant L. Vincent, James William Ashmead, William Gerald Dimaio, Jr.
Принадлежит: EI Du Pont de Nemours and Co

A seal-less, hand-held dispensing device includes a support platform having a pair of finger gripping surfaces; first and second hollow members on the platform; and a compatibly sized plunger disposed in each hollow member. Each hollow member has a largest inside dimension in the range from about 0.2 mm to about 0.3 mm and each plunger has a largest outside dimension that is sized for compatible receipt within a hollow member. The largest outside dimension of each compatibly sized plunger is from about eighty percent (80%) to about ninety-five percent (95%) of the largest inside dimension of a hollow member. An actuator having a thumb actuating surface thereon is operatively engagable with each plunger. When fully extended a predetermined maximum finger span is defined between the actuating surface and the gripping surfaces, the maximum finger span being not greater than about 150 mm.

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Номер записи: 3
31-05-2012 дата публикации

Anatomically engineered configured article

Номер: US20120136313A1
Автор: Joseph O. Smith
Принадлежит: Individual

An engineered designed article providing multi-directional support. Portions of three or more overlapping, circular-like bodies are integrated on a flexible planar membrane into products, such as bandages, headgear, tool handles, lumbar pillows, backpacks, cervical supports, and back supports, to offer a multi-directional, (360° quadrant) support or pressure-concentrating area, to enhance specific support at the medial, lateral, inferior and/or superior part of a body part. The article can be made of material that is waterproof, acts as a shock absorber, and provides multi-directional support. Medicaments can be infused into the pressure-concentrating area of the support or into the membrane itself. An aperture for accepting IV needles is also provided.

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Номер записи: 4
07-06-2012 дата публикации

Liquid applicator and method of use

Номер: US20120138070A1
Автор: George Reed, Richard J. Stenton
Принадлежит: Medlogic Global Ltd

An applicator for dispensing uniform thickness layers of liquid to surfaces and especially surgical sealants to surgical sites to create, in situ, a surgical incise drape is disclosed. The applicator employs a supported thin layer of foam which achieves layer thickness which are substantially independent of the pressure applied to the applicator during use. Methods of using the applicator are also disclosed.

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Номер записи: 5
07-06-2012 дата публикации

Chitosan spreading system using low temperature atmospheric pressure plasma

Номер: US20120143121A1
Автор: Han Young Yu, Won Ick Jang, Yark Yeon Kim, Yong Ju Yun
Принадлежит: Electronics and Telecommunications Research Institute ETRI

Provided is a chitosan spreading system using low temperature atmospheric pressure plasma. The system includes a dielectric tube of hollow cylindrical shape including a gas inlet supplied with a carrier gas and a plasma outlet spraying low temperature atmospheric pressure plasma generated therein, a first electrode provided in the dielectric tube, an power supply unit configured to apply an electric power to the first electrode, a carrier gas supply unit configured to supply a carrier gas into the gas inlet of the dielectric tube, and a chitosan supply unit configured to supply chitosan into the low temperature atmospheric pressure plasma generated in the dielectric tube

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Номер записи: 6
16-08-2012 дата публикации

Visual, bi-audible, and bi-tactile metered-dose transdermal medicament applicator

Номер: US20120205393A1
Автор: Ramiro M. Perez
Принадлежит: Individual

A bi-audible, bi-tactile, and visual transdermal delivery apparatus for delivering specific desired quantities of cream-base medicament or any flowable composition; comprising: a revolving platform with equispaced side tabs stemming from an outer and inner base rim responsible for yielding said bi-audible and bi-tactile sensations upon interaction with ticker tabs projecting form the bottom exterior wall of the house; a threaded screw-complex that interacts with an elevator to transport the medicament upwards; a house that confines an inner chamber to store the medicament; an applicator pad with a center outlet where the composition exits the chamber; and a safety cap. Equispaced digit tabs on the outer side wall of the rotatable platform indicate the amount to be delivered. The platform rotates 18° clockwise per actuation against equispaced line demarcations on the house delivering roughly a 1/20 th of a milliliter of composition.

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Номер записи: 7
13-09-2012 дата публикации

Dispensing applicator for fluids

Номер: US20120230753A1
Автор: Jack W. Kaufman, James Brown
Принадлежит: BIOMED PACKAGING SYSTEMS INC

Disclosed is a hand-held dispensing applicator comprising a source of fluid, a frangible applicator tip attached to the fluid source, and an absorbent member attached to the frangible applicator tip. When the frangible applicator tip is broken, fluid flows from the source to the absorbent member, whereby the fluid is applied and spread on a surface. Preferably, the frangible applicator tip comprises a support element permanently connected to the fluid source, a relatively rigid tongue element extending outwardly of the support element, and a frangible region there between. Preferably, the tongue element comprises ribs for reinforcing the tongue element to resist unintentional breaking of the frangible region. More preferably, the applicator tip comprises a semi-permeable or non-permeable cover disposed around the frangible region to control the speed and direction of the dispersion of the fluid in the absorbent member. Adaptive embodiments allow the generation of designs applicable to a particular medical purpose.

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Номер записи: 8
20-09-2012 дата публикации

Medicament Dispensing Devices and Methods

Номер: US20120238995A1
Автор: Michael I. Lewis
Принадлежит: CYTO BIOTICS LLC

A medicament dispensing device including a substantially rigid carpule body which has a dispensing end and an actuation end opposite the dispensing end. The carpule body is substantially tubular and thus defines a carpule bore. The device further includes a plunger operatively disposed within the carpule bore having a plunger actuator near the actuation end of the carpule body and a plunger tip opposite the plunger actuator. The plunger tip and an orifice at the dispensing end of the carpule bore define a medicament volume which may be loaded with a medicament selected to achieve specific therapeutic goals. The carpule body may also include a wound depth scale. The depth scale is typically associated with the dispensing end of the carpule body. Similarly, the medicament dispensing device may include a dosage scale. Also disclosed are methods of dispensing medicaments.

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Номер записи: 9
15-11-2012 дата публикации

Powder dispenser with cartridge

Номер: US20120285987A1
Автор: John LEIER
Принадлежит: Individual

Described are articles that serve as integrated dispensers or applicators for powdered compositions. Primarily, the powder-dispensing articles of the invention include a housing in which a cartridge is disposed that can move in relation to the housing, typically by depressing a plunger that protrudes from the housing. The housing unit contains a housing access port that provides access to the preferably replaceable cartridge. The cartridge also contains an orifice, referred to as a cartridge access port, in the cartridge wall. The housing and cartridge access ports are brought into alignment by the user, for example, by depressing a plunger that causes the cartridge to move in relation to the housing by compressing a biasing member. Such port alignment exposes the powdered composition inside the cartridge.

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Номер записи: 10
13-12-2012 дата публикации

Tape Preparation

Номер: US20120316519A1
Автор: Masanori Uematsu
Принадлежит: Teikoku Seiyaku Co Ltd

A tape preparation is provided which does not use a backing such as a plastic film, knit or a woven fabric, or a nonwoven fabric, has very high conformability to skin, and is easy to use at the time of application. There is provided a tape preparation 1 that is produced by laminating a drug-containing adhesive layer 4 on the printed ink layer 3 side of a cover film 2 with printing thereon and covering the drug-containing adhesive layer with a release film 5. In this tape preparation, the adhesive strength between the cover film and the printed ink layer is higher than the adhesive strength between the drug-containing adhesive layer and the release film, and the adhesive strength between the printed ink layer and the drug-containing adhesive layer is higher than the adhesive strength between the cover film and the printed ink layer.

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Номер записи: 11
07-02-2013 дата публикации

Dead skin removing device and method for forming the same

Номер: US20130035650A1
Автор: Wei-Jen Wang
Принадлежит: Individual

A dead skin removing device for a user's hand includes a liquidproof plastic glove which defines an inner space and which includes a palm piece and a back piece that are configured to be matingly plastic-welded to each other, and a patch member which is bonded to a portion of the palm piece or the back piece. The patch member is soaked with an exfoliating agent such that once the user's hand is inserted into the liquidproof plastic glove, a region of the user's hand is brought into intimate contact with the exfoliating agent. A method of forming the dead skin removing device is also disclosed.

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Номер записи: 12
14-02-2013 дата публикации

Laser Assisted Nail Avulsion

Номер: US20130041308A1
Автор: David R. Hennings, Elwood Phillips, Randolph W. Nordyke
Принадлежит: New Star Lasers Inc

A method of treating inaccessible microbial infections, the method comprising the steps of exposing the microbe, irradiating the microbe with infrared radiation and cooling such that heat inactivates the pathogen and stimulates a wound healing response in the patient.

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Номер записи: 13
21-03-2013 дата публикации

Device for Preparing Dilute Disinfectant Solution

Номер: US20130072867A1
Автор: Dakin Myles H. E.
Принадлежит: Hypo-Stream Limited

A portable device for mixing a dilute disinfectant solution comprising 1. A portable device for mixing a dilute disinfectant solution , comprising:a disinfectant reservoir holding said disinfectant solution,a chamber connected to said disinfectant reservoir for holding a predetermined amount of dilutant, and,disinfectant discharging means for discharging a predetermined amount of said disinfectant solution from said first reservoir to be mixed with said predetermined amount of dilutant, whereby said device provides the dilute disinfectant solution at a fixed dilution determined by the ratio of the predetermined amount of said disinfectant solution to the predetermined amount of dilutant.2. A device according to further comprising an indicator reservoir holding an indicator indicating the activity of the dilute disinfectant solution.3. A device according to wherein the indicator reservoir is separate from the disinfectant reservoir and the chamber and the device further comprises indicator discharging means for discharging a predetermined amount of said indicator from said indicator reservoir to be mixed with said predetermined amount of dilutant and said predetermined amount of disinfectant.4. A device according to wherein the indicator is a dye.5. A device according to claim 3 , wherein the dye is selected so that the dilute disinfectant solution is colorless within 45 minutes to 60 minutes.6. A device according to wherein the indicator is a flavor.7. A device according to claim 6 , wherein the flavor is selected so that there is a noticeable degradation of the flavor within 45 minutes to 60 minutes.8. A device according to claim 1 , wherein the disinfectant solution in the disinfectant reservoir is a stabilized sodium hypochlorite solution at 1% sodium hypochlorite and the dilutant is water.9. A device according to claim 8 , wherein the ratio of the predetermined amount of disinfectant solution to predetermined amount of water is in the range between 1 to 5 and 1 ...

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Номер записи: 14
21-03-2013 дата публикации

Transdermal compositions comprising an active agent layer and an active agent conversion layer

Номер: US20130072884A1
Автор: Jianye Wen, Richard Hamlin
Принадлежит: Teikoku Pharma USA Inc

Transdermal compositions are provided. Aspects of the transdermal compositions include: an active agent layer and a conversion layer, where the conversion layer includes a weak base and, optionally, a carboxylated component. Also provided are methods of using the transdermal compositions and kits containing the transdermal compositions.

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Номер записи: 15
28-03-2013 дата публикации

PHARMACEUTICAL COMPOSITIONS OF IBUPROFEN AND AN H2 RECEPTOR ANTAGONIST

Номер: US20130078287A1
Автор: Duncan lain, Tidmarsh George F.
Принадлежит: HORIZON PHARMA USA, INC.

Pharmaceutical compositions of a Hreceptor antagonist and ibuprofen are provided herein. The compositions comprise, e.g., a core and a shell separated by a barrier layer, bilayered or trilayered compositions, or liquid formulations. Also provided are methods of making the pharmaceutical compositions, and methods of treatment comprising administering the pharmaceutical compositions. Also provided is a method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which a pharmaceutical composition comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of an HRA, such as famotidine, is administered three times per day 143.-. (canceled)44. A pharmaceutical composition having a bilayer architecture comprising:a first layer comprising famotidine and further comprising hypromellose (hydroxypropylmethylcellulose), anda second layer comprising ibuprofen,wherein the pharmaceutical composition is suitable for three times per day (TID) administration, andwherein both the famotidine and ibuprofen are formulated for immediate release at about the same time.45. The pharmaceutical composition of claim 44 , wherein the pharmaceutical composition comprises about 24 mg to about 28 mg famotidine.46. The pharmaceutical composition of claim 44 , wherein the pharmaceutical composition comprises about 750 mg to about 850 mg ibuprofen.47. The pharmaceutical composition of claim 44 , wherein the first layer further comprises at least one lubricant.48. The pharmaceutical composition of claim 47 , wherein the at least one lubricant is magnesium stearate.49. The pharmaceutical composition of claim 44 , wherein the first layer further comprises at least one binder other than hypromellose (hydroxypropylmethylcellulose).50. The pharmaceutical composition of claim 49 , wherein the at least one binder is microcrystalline cellulose.51. The pharmaceutical composition of claim 44 , wherein the first layer further comprises ...

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Номер записи: 16
28-03-2013 дата публикации

Ultrasonic Surface Treatment Device and Method

Номер: US20130079732A1
Автор: Burt Diane Joyce, Creek John Aubrey, Evans Christopher Michael, Hindle Benjamin David
Принадлежит: RECKITT BENCKISER LLC

Disclosed are devices which generate a mist of a treatment composition, viz, an aerosolized treatment composition which imparts a technical benefit to surfaces, or airspaces, which come into contact with the said aerosolized treatment composition. Also disclosed are methods for the treatment of surfaces utilizing the devices of the invention. 1. A hand-holdable , portable device for the treatment of a surface or of an airspace which device generates a mist of a treatment composition which imparts a technical benefit to treated surfaces or airspaces which come into contact with the said aerosolized treatment composition , the device comprising:a mist generator means,a control circuit for operating the mist generator means,a reservoir for the fluid product to be aerosolized,a means for supplying the mist generating means with the fluid product,a housing,and optionally at least one flow directing nozzle, flow directing implement or flow directing orifice adapted to direct the flow of a mist generated by the mist generating means out from the housing and towards a surface or into an airspace or both.2. A hand-holdable claim 1 , portable device according to claim 1 , wherein the mist generating means comprises a vibrating member and a piezoelectric actuator.3. A hand-holdable claim 1 , portable device according to claim 1 , wherein the mist generating means comprises a metal or ceramic plate as the vibrating member which is attached to a piezoelectric material.4. A hand-holdable claim 1 , portable device according to wherein the reservoir is refill unit.5. A hand-holdable claim 1 , portable device according to wherein the reservoir of the device is a refill unit claim 1 , the device includes a piezoelectric actuator claim 1 , the refill unit includes a vibrating member claim 1 , wherein the device and the refill unit are configured such that when the refill unit is properly installed in the device the piezoelectric actuator and the vibrating member interact to form the ...

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Номер записи: 17
28-03-2013 дата публикации

Surface Treatment Device and Method

Номер: US20130079733A1
Автор: Burt Diane Joyce, Creek John Aubrey, Evans Christopher Michael, Hindle Benjamin David
Принадлежит: RECKITT BENCKISER LLC

Disclosed are devices which generate a mist of a treatment composition, viz, an aerosolized treatment composition which imparts a technical benefit to surfaces, or airspaces, which come into contact with the said aerosolized treatment composition. Also disclosed are methods for the treatment of surfaces utilizing the devices of the invention. 1. A mist generating device which generates an aerosolized treatment composition which composition imparts a technical benefit to surfaces , or airspaces , which come into contact with the said aerosolized treatment composition which device comprises:a mist generator means,a control circuit for operating the mist generator means,a reservoir for a fluid product to be aerosolized,means for supplying the a mist generator with the fluid product,a housing, andoptionally, at least one flow directing nozzle or flow direcfinorifice adapted to direct the flow of a mist generated by the mist generator means out from the device.2. (canceled)3. A mist generating device according to claim 1 , wherein the mist generator means comprises a porous or micropierced metal or ceramic plate claim 1 , and a vibrating member.4. A mist generating device according to claim 3 , wherein the vibrating member comprises a piezoelectric material.5. A mist generating device according to claim 1 , wherein the mist generator means comprises an electrostatic spray device.6. A mist generating device according to claim 1 , wherein the mist generator means comprises an ultrasonic nozzle device.7. A mist generating device according to claim 1 , wherein the mist generator means comprises a tubular aerosol generator which includes a tube having a first and a second end claim 1 , a heater arranged relative to the tube for heating the tube claim 1 , a source of material to be volatilized claim 1 , the second end of the tube being in communication with the source of material claim 1 , a valve operatively located between the source of material and the tube claim 1 , the ...

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Номер записи: 18
18-04-2013 дата публикации

Healing Wounds by Restoring Physiological Norms

Номер: US20130096516A1
Автор: Schaefer Joseph H.
Принадлежит:

A method of treating a wound by restoring a bodies' physiological norms is disclosed. A wound dressing is applied over the wound in which the wound dressing has an inlet and an outlet and furthermore forms a substantially airtight cover over the wound. A vapor is supplied to the wound dressing via the inlet. The wound is warmed by condensing the vapor into a condensate on a surface of the wound, thereby releasing a latent heat of vaporization and adding moisture to the wound. The excess condensate is removed from the wound dressing via the outlet. 1. A method of treating a wound by restoring a bodies' physiological norms , the method comprising:applying a wound dressing over the wound, the wound dressing having an inlet and an outlet and forming a substantially airtight cover over the wound;supplying a vapor to the wound dressing via the inlet; release latent heat to warm the wound,', 'release liquid to moisturize the wound, and, 'condensing the vapor into a condensate on the surface of the wound to bothremoving an excess amount of the condensate and an uncondensed portion of the vapor from the wound dressing via the outlet.2. The method of further comprising preventing local thermoregulatory vasoconstriction by warming the wound.3. The method of further comprising speeding up a rate of cellular physiological functions by warming the wound.4. The method of further comprising maintaining a desired moisture balance at the wound by regulating the condensate used to moisturize the wound and the excess amount of the condensate removed via the outlet.5. The method of wherein the method simultaneously prevents hypoxia claim 1 , hypothermia and inadequate moisture levels at a site of the wound.6. The method of wherein a dew point temperature of the vapor coincides with normal human body temperature (37 degrees C.) claim 1 , thereby allowing the latent heat to be released to tissues of the wound at this temperature without elevating a temperature at the vapor.7. The method ...

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Номер записи: 19
25-04-2013 дата публикации

MICRODERMABRASION APPARATUS AND METHOD

Номер: US20130102978A1
Автор: Ignon Roger, Nicolas Ed F.
Принадлежит: EDGE SYSTEMS CORPORATION

According to some embodiments, a system for treating skin includes a handpiece assembly comprising a tip and a main body portion, the main body portion comprising an interior cavity and at least one canister configured to store at least one of a treatment material and a waste material. The treatment material and/or the waste material is in fluid communication with the tip. 1. A system for treating skin , the system comprising:a handpiece assembly comprising a tip and a main body portion, the main body portion comprising an interior cavity; anda first canister configured to store at least one treatment material;a second canister configured to store waste material;wherein the treatment material and the waste material are in fluid communication with the tip.2. The system of claim 1 , further comprising a fluid transfer device for transferring the treatment material to the tip and the waste material to the canister.3. The system of claim 1 , further comprising a conduit configured to place the first and second canisters in fluid communication with the tip.4. The system of claim 3 , wherein the conduit is routed within the interior cavity of the main body portion.5. The system of claim 3 , wherein the conduit comprises at least two passages claim 3 , each passage configured to transfer a different material to the tip.6. The system of claim 1 , wherein the handpiece assembly and the first and second canisters form a generally unitary structure.7. The system of claim 1 , wherein the handpiece assembly and at least one of the first and second canisters are substantially separated.8. The system of claim 1 , wherein the first canister comprises at least one compartment claim 1 , the compartment configured to contain a treatment fluid.9. The system of claim 8 , wherein the treatment fluid comprises a serum.10. The system of claim 1 , wherein the tip is removable.11. The system of claim 9 , wherein the serum comprises an anti-oxidant12. The system of claim 9 , wherein the serum ...

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Номер записи: 20
02-05-2013 дата публикации

DISPOSABLE APPLICATOR ASSEMBLY

Номер: US20130104324A1
Автор: Anderson Marcus, Greer, JR. LES
Принадлежит: UNICEP PACKAGING, INC.

A disposable applicator assembly includes a handle of a diameter substantially larger than the diameter of an applicator stick. The applicator assembly includes a casing, the applicator stick, and an applicator (e.g., a swab). A support structure is disposed within the casing and engages the applicator stick. A product may be housed in the casing for delivery by the applicator. The applicator assembly may be formed of a single material that is suitable for an injection molding process. 1. An applicator assembly comprising: a first hollow portion having an inside diameter;', 'a second hollow portion having an inside diameter substantially the same as the inside diameter of the first hollow portion;, 'a casing, the casing comprisinga stick contained within the first and second hollow portions of the casing, having an applicator disposed at one end of the stick; anda support structure coupled to the casing and engaging the stick, the support structure at least partially between the casing and the stick.2. The applicator assembly of claim 1 , further comprising a failure zone for opening the applicator assembly.3. The applicator assembly of claim 2 , the failure zone comprising a reduction in wall thickness of the casing or a weaker portion of the casing claim 2 , and wherein the failure zone connects the first and second hollow portions.4. The applicator assembly of claim 1 , an end of the first hollow portion being crimped.5. The applicator assembly of claim 1 , the support structure comprising ribs disposed substantially parallel to a portion of the length of the second hollow portion and coupled to the inside diameter of the second hollow portion.6. The applicator assembly of claim 5 , the ribs being coupled substantially tangent to a surface of the inner diameter of the second hollow portion and extending radially from respective points at which the ribs engage the stick.7. The applicator assembly of claim 1 , the support structure comprising:a first cylinder, the ...

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Номер записи: 21
09-05-2013 дата публикации

PATCH FOR TREATING AND ALLEVIATING SYMPTOMS OF SKIN DISEASES ACCOMPANIED BY EFFUSION OF BLOOD PROTEINS

Номер: US20130116516A1
Автор: Choi Seong Hyun
Принадлежит: Biopid Corporation

Provided is a patch for treating skin diseases or alleviating symptoms of the skin diseases involving an exudation of blood proteins, or for absorbing blood proteins exuded to the skin. 1. A patch for treating skin diseases or alleviating symptoms of the skin diseases involving an exudation of blood proteins , the patch comprising:a) a polymer matrix with a mesh structure; andb) a polar resin bonding with proteins contained in the matrix and/or a resin bonding with proteins through a hydrophobic bonding.2. The patch for treating the skin diseases or alleviating the symptoms of the skin diseases according to claim 1 , wherein the polymer matrix with the mesh structure is a micro-mesh structure of a complex carbohydrate selected from the group consisting of agar and agarose claim 1 , or a micro-mesh structure produced by using polyacrylamide claim 1 , latex claim 1 , polystyrene claim 1 , polyvinyl chloride claim 1 , silicone polyurethane claim 1 , or cellulose fiber.3. The patch for treating the skin diseases or alleviating the symptoms of the skin diseases according to claim 1 , wherein the polar group is agarose claim 1 , sephadex claim 1 , or sepharose having DEAE (Diethylaminoethyl)-group; agarose claim 1 , sephadex claim 1 , or sepharose having CM (Carboxymethyl)-group; agarose claim 1 , sephadex claim 1 , or sepharose having trimethylammonium-group; a resin having a functional group claim 1 , such as sulfonyl- or sulfonic acid derivatives as S-cation exchange resin; or a polar resin (charged resin) of hydroxylapatite granules or polystyrene structure.4. The patch for treating the skin diseases or alleviating the symptoms of the skin diseases according to claim 1 , wherein the resin bonding with proteins through the hydrophobic bonding (hydrophobic interaction) is a resin containing C4 to C10 hydrocarbon chain.5. The patch for treating the skin diseases or alleviating the symptoms of the skin diseases according to claim 1 , wherein the patch is prepared by ...

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Номер записи: 22
16-05-2013 дата публикации

MEDICAL SKIN APPLICATOR APPARATUS

Номер: US20130123717A1
Автор: CABLE, Fetterroll Andrew, JR. Frank A., Tauer Mark
Принадлежит: COVIDIEN LP

A medical skin applicator apparatus includes a fluid housing having a fluid chamber for storing a medical agent and an applicator coupled to the housing. The fluid housing has a penetrable wall to permit access to the fluid chamber and release of the medical agent therefrom. The applicator includes an applicator surface for applying the medical agent to a patient. The applicator has a penetrating member adapted to penetrate the penetrable wall of the fluid housing upon achieving a predetermined coupled relation of the fluid housing and the applicator, to thereby permit the medical agent to be dispensed from the fluid chamber and applied to the patient with the applicator surface. 159-. (canceled)60. A medical skin applicator apparatus , which comprises:a fluid housing defining a longitudinal axis and having a fluid chamber for storing and selectively releasing a medical agent; andan applicator coupled to the fluid housing, the applicator including an applicator surface in fluid communication with the fluid chamber for applying the medical agent to a patient, the applicator surface defining an asymmetric configuration characterized by having a relatively enlarged portion and a relatively narrowed portion extending from the enlarged portion.61. The medical skin applicator apparatus according to wherein the relatively narrowed portion includes opposed generally concave surfaces extending to a leading surface which interconnects the concave surfaces.62. The medical skin applicator apparatus according to wherein the leading surface is generally arcuate.63. The medical skin applicator according to wherein the enlarged section includes opposed generally convex surfaces extending from a trailing surface which interconnects the convex surfaces.64. The medical skin applicator apparatus according to wherein the applicator defines a complex curve configuration in plan claim 60 , the complex curve configuration including a pair of opposed generally convex surfaces and a pair of ...

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Номер записи: 23
16-05-2013 дата публикации

Pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid

Номер: US20130123720A1
Автор: Gritt Rasmussen, Jens Hansen, Karsten Petersson, Marianne Lind, Mette Rydahl Sonne
Принадлежит: Leo Pharma AS

The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative and a corticosteroid, and its use in the treatment of dermal diseases and conditions. The spray comprises especially a propellant selected from the group consisting of dimethyl ether, diethyl ether and methylethyl ether or a mixture thereof and further a pharmaceutically acceptable lipid carrier solubilised or suspended in said propellant.

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Номер записи: 24
23-05-2013 дата публикации

Surgical method and apparatus

Номер: US20130131457A1
Автор: Tamer A. Seckin
Принадлежит: Individual

An apparatus for use in connection with an endoscopic surgery comprises an elongated body adapted to be placed at least partially in the vagina of a female patient partially passing through the wall of the vagina such that an end portion of said elongated element is introduced into rectouterine pouch; the elongated body comprises at least an attachment means for accommodating at least a part of at least a surgical instrument comprising an end portion adapted to be received inside the vagina, the surgical instrument and the apparatus are movable to each other. An endobag having an elongated port is provided through the vagina into the pelvis. A method for use in a pelvic or peritoneal surgery is provided wherein at least an elongated end portion of a surgical instrument is provided in the cavity of the uterus through the vagina of a female patient such that the uterus can be repositioned by manipulating the surgical instrument and an incision is performed on the vaginal wall for accessing to the rectouterine pouch, a flexible element is provided in pelvis wherein the flexible element is looped around the uterus such that the flexible element encircles the uterus.

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Номер записи: 25
23-05-2013 дата публикации

Disposable Eye Mask Slip

Номер: US20130131613A1
Автор: Elkins Laura Susan
Принадлежит:

An eye mask slip device to dispense the contents of a gel pack to a user may include a gel pack pouch to house the gel pack and a pair of ear arms to connect to the gel pack pouch to extend over the ear of the user. The gel pack pouch may include a back wall being permeable to dispense the contents of the gel pack. The gel pack pouch may include a front wall and a sidewall which may connect the front wall and back wall and extend around the periphery of the front wall and the wall. The sidewall may include a slit to allow the gel pack to be inserted and removed from the gel pack pouch. The gel pack pouch may include a fastener to close the slit. 1) An eye mask slip device to dispense the contents of a gel pack to a user , comprising:a gel pack pouch to house the gel pack;a pair of ear arms to connect to the gel pack pouch to extend over the ear of the user;wherein the gel pack pouch includes a back wall being permeable to dispense the contents of the gel pack.2) An eye mask slip device to dispense the contents of a gel pack to a user as in claim 1 , wherein the gel pack pouch includes a front wall and a sidewall which may connect the front wall and back wall and extend around the periphery of the front wall and the wall.3) An eye mask slip device to dispense the contents of a gel pack to a user as in claim 2 , wherein the sidewall includes a slit to allow the gel pack to be inserted and removed from the gel pack pouch.4) An eye mask slip device to dispense the contents of a gel pack to a user as in claim 3 , wherein the gel pack pouch includes a fastener to close the slit. The present invention claims priority under 35 USC section 119 and based upon the provisional application which was filed on Aug. 25, 2011 with a Ser. No. of 61/527,261.The present invention relates to an eye mask and more particularly to an eye mask having a gel pack pouch to dispense treatment.The following patents and patent applications are incorporated by reference in their entirety.U.S. Pat. ...

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Номер записи: 26
30-05-2013 дата публикации

Port and Surface Cleaning Devices and Techniques

Номер: US20130138085A1
Автор: Tennican Patrick O.
Принадлежит: HYPROTEK, INC.

This disclosure describes example antimicrobial compositions that may be used in combination with IV port cleansing caps, protective caps, or both. According to another implementations, the disclosure describes various cap devices that may be used in combination with the antimicrobial composition to cleanse, sanitized, and/or disinfected a surface. 1. A medical device comprising: a cylindrical cavity, the cylindrical cavity having an opening and a flange at the opening;', 'an outer surface configured to interface with a user;', 'an inner surface within the cylindrical cavity; and', 'an energy director located on the flange and extending perpendicular to the opening of the cylindrical cavity., 'a cap comprising2. The medical device as recited in claim 1 , wherein the cap is comprised of a polypropylene claim 1 , a polyethylene claim 1 , a copolymer material or mixtures thereof.3. The medical device as recited in claim 1 , wherein the flange is configured to extend radially from the perimeter of the cylindrical cavity.4. The medical device as recited in claim 1 , further comprising a protective cover attached to at least the energy director and covering at least a portion of the opening.5. The medical device as recited in claim 4 , further comprising a foam insert within the cylindrical cavity wherein the foam insert is maintained in a compressed state while the protective cover is attached and the foam insert is configured to extend outside the opening of the cylindrical cavity when the protective cover is removed.6. The medical device as recited in claim 5 , wherein a surface of the foam insert extending outside the opening of the cylindrical cavity comprises different surface treatments claim 5 , finishes or contours.7. The medical device as recited in claim 1 , further comprising an antimicrobial agent disposed within the foam insert.8. The medical device as recited in claim 7 , wherein the antimicrobial agent comprises:about 5 to about 50 mg/ml of ...

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Номер записи: 27
06-06-2013 дата публикации

DEVICES WITH SELECTIVELY PERMEABLE BARRIERS

Номер: US20130144133A1
Автор: FORSTER Ian J.
Принадлежит: AVERY DENNISON CORPORATION

Devices having selectively permeable barriers are provided with a substrate, a first layer overlaying at least a portion of the substrate, and a second layer overlaying at least a portion of the first layer. The first layer has at least one first pore and the second layer has at least one second pore. At least a portion of the first and/or second layers are movable with respect to each other between an open condition and a closed condition in response to a change in an environmental factor. In the open condition, the first and second pores are substantially aligned to allow fluid communication between the substrate and the outside environment. In the closed condition, the first and second pores are substantially misaligned to prevent fluid communication between the substrate and the outside environment. 1. A device for allowing selective communication between a substrate and an outside environment , comprising:a substrate;a first layer overlaying at least a portion of the substrate and having at least one first pore; anda second layer overlaying at least a portion of the first layer and having at least one second pore, whereinat least a portion of the first and/or second layers are movable with respect to each other between an open condition and a closed condition in response to a change in an environmental factor,the first and second pores being substantially aligned in the open condition to allow fluid communication between the substrate and the outside environment, andthe first and second pores being substantially misaligned in the closed condition to prevent fluid communication between the substrate and the outside environment.2. The device of claim 1 , wherein the first and second pores are completely misaligned in the closed condition.3. The device of claim 1 , further comprising sensor material associated with the substrate.4. The device of claim 1 , further comprising an RFID chip and antenna associated with the substrate.5. The device of claim 1 , further ...

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Номер записи: 28
06-06-2013 дата публикации

ACTIVE AGENT DELIVERY DEVICE

Номер: US20130144221A1
Автор: Burstein Pinchas, Daily David, Keenan Guy, Mareli Lior, Raday Lior
Принадлежит: Bioline RX, Ltd.

A device for delivering an active agent to a tissue (), comprising; a housing () including a reservoir () for containing said active agent; a delivery tip () being in fluid communication with said reservoir; and, a delivery mechanism () capable of delivering a predetermined amount of said active agent and releasing the same upon contact between said delivery tip and said tissue. 160-. (canceled)61. A device for delivering an active agent to a tissue , comprising:a. a housing including a reservoir for containing said active agent;b. a delivery tip being in fluid communication with said reservoir; and,c. a delivery mechanism capable of delivering a predetermined amount of said active agent and releasing the same upon contact between said delivery tip and said tissue.62. The device according to claim 61 , wherein said delivery tip is made of substantially porous and substantially rigid material adapted to delay passage of said predetermined amount of said active agent through said delivery tip; further wherein said delivery tip is adapted to: (i) absorb at least part of said predetermined amount of said active agent; and (ii) discharge at least part of said predetermined amount of said active agent upon a contact of said delivery tip with said tissue.63. The device according to claim 61 , wherein said delivery mechanism comprises a plunger.64. The device according to claim 63 , wherein said plunger is adapted to actuate pushing forces on said active agent claim 63 , said pushing forces are adapted to force said predetermined amount of said active agent to be delivered to said delivery tip.65. The device according to claim 64 , wherein said plunger is adapted to actuate said pushing forces on said active agent said via a first piston located between said plunger and said active agent.66. The device according to claim 64 , further comprising a second piston located within said reservoir between said active agent and said delivery tip claim 64 , said second piston adapted ...

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Номер записи: 29
06-06-2013 дата публикации

MEDICAL ADHESIVE PATCH

Номер: US20130144226A1
Автор: Matsushima Atsushi, Nishihara Tsuguki, Shima Takito, Takada Yasunori, Takamiya Tsuyoshi, Tateishi Tetsurou, Yoshida Chiaki
Принадлежит: HISAMITSU PHARMACEUTICAL CO., INC.

A medical adhesive patch includes: a support film including a barrier layer which contains polyvinyl alcohol and a layered inorganic compound, and which is laminated on one surface of a support including polyurethane; an adhesive layer which contains a medicine, and which is laminated on the barrier layer of the support film, a degree of saponification of the polyvinyl alcohol is equal to or more than 70% and equal to or less than 95.5%. 1. A medical adhesive patch comprising:a support film comprising a barrier layer containing polyvinyl alcohol and a layered inorganic compound, the barrier layer being laminated on one surface of a support including polyurethane; andan adhesive layer containing a medicine, being laminated on the barrier layer of the support film, whereina degree of saponification of the polyvinyl alcohol is equal to or more than 70% and equal to or less than 95.5%.2. The medical adhesive patch according to claim 1 , wherein the layered inorganic compound is montmorillonite. 1. Field of the InventionThe present invention relates to a medical adhesive patch and particularly to a medical adhesive patch which is used for percutaneous administration of a medicine.Priority is claimed on Japanese Patent Application No. 2010-171215, filed July 29, 2010, the content of which is incorporated herein by reference.2. Description of Related ArtA tape in which an adhesive layer is formed on one surface of a sheet-shaped or film-shaped support is widely used for various purposes such as in the medical or industrial fields. In the medical field, a percutaneous administration of medicine is performed using a medical adhesive patch which mixes a medicine to an adhesive layer. The administration of a medicine with the medical adhesive patch is advantageous since it is only slightly invasive to a patient, and the study thereof is progressed in order to broaden the applicable range of medicines.A gas barrier film disclosed in Patent Document 1 (Japanese Unexamined Patent ...

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Номер записи: 30
06-06-2013 дата публикации

STRUCTURES FOR TRANSDERMAL DRUG DELIVERY

Номер: US20130144261A1
Автор: CHOWDHURY Dewan Fazlul Hoque
Принадлежит:

A preparation for the transdermal delivery of a biologically active substance into the body of a patient comprises particles of a formulation comprising the active substance. The particles are irregular in size and shape and may be produced by a low cost manufacturing method such as grinding from a thin film. The particles are angular, i.e. they have sharp edges and corners that allow them to penetrate the outer layer of the skin when subjected to pressure from a roller or an array of blunt-tipped microstructures. Sucrose may be used as an excipient with the active substance to form suitably rigid and angular particles. 1. A preparation suitable for transdermal delivery into the body of a patient , the preparation comprising particles of a formulation that is soluble or biodegradable in the body , the particles being rigid , irregular in shape and angular , whereby they are capable of penetrating the surface of the skin or of a cornea of the patient.2. A preparation according to claim 1 , wherein the formulation comprises a biologically active substance.3. A preparation according to claim 2 , wherein the formulation further comprises at least one excipient in addition to the active substance.4. A preparation according to claim 3 , wherein the excipient is sucrose.5. A preparation according to claim 4 , wherein the ratio of sucrose to the active substance is greater than 60:40.6. A preparation according to claim 5 , wherein the ratio of sucrose to the active substance is less than 20:1.7. A preparation according to claim 1 , wherein at least 50% of the particles have at least one corner characterized in that every pair of faces of the particle that meet at the corner meet at an angle no greater than 90°.8. A preparation according to claim 1 , wherein the mean size of the particles is between 10 nm and 1 mm.9. A preparation according to claim 8 , wherein the mean size of the particles is between 1 μm and 100 μm.10. A transdermal patch comprising:a body layer;means for ...

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Номер записи: 31
20-06-2013 дата публикации

Skin Patch Sheet, Use Thereof, and Method for Attaching Skin Patch Sheet

Номер: US20130152944A1
Автор: Kajiwara Takahiro, Okada Masaki, Takezaki Akihito
Принадлежит:

Provided are a skin patch sheet including a carrier sheet, an adhesive patch and a release liner laminated in this order, in which (a) the adhesive patch includes two layers, namely, a backing and an adhesive layer having the same shape; (b) the carrier sheet is adjacent to the backing of the adhesive patch; (c) the skin patch sheet includes a grip section and a body section; (d) in the body section or the body section and grip section, the area of the release liner is larger than the area of the adhesive patch; (e) the boundary between the grip section and the body section is a slit line formed by a slit; and (f) the slit extends from the side of the release liner, penetrating into the adhesive patch, up to a depth in the range of greater than or equal to 20% and less than 50% of the thickness on the adhesive patch side of the carrier sheet; a skin patch sheet in which plural sheets of adhesive patches on which carrier sheets are laminated are formed in a parallel arrangement on a release liner; use of the skin patch sheet by attaching the skin patch sheet to the skin surface in order to prevent direct scratching of an affected site of the skin, or by attaching the skin patch sheet to the face for a lift-up effect; and a method for attaching the skin patch sheet. 1. A skin patch sheet comprising a carrier sheet , an adhesive patch and a release liner laminated in this order , wherein(a) the adhesive patch comprises two layers of a backing and an adhesive layer having the same shape,(b) the carrier sheet is adjacent to the backing of the adhesive patch,(c) the skin patch sheet comprises a grip section and a body section,(d) in the body section, the area of the release liner is larger than the area of the adhesive patch,(e) the boundary between the grip section and the body section is a slit line formed by a slit, and(f) the slit cuts into the skin patch sheet from the release liner side, penetrating into the adhesive patch, to a position at which at least half or ...

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Номер записи: 32
27-06-2013 дата публикации

Optical Treatment Methods

Номер: US20130165839A1
Автор: ONeil Michael P.
Принадлежит:

A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects related to exposing to a light output a skin portion including a condition treatable in whole or in part with light. In one exemplary embodiment for skin treatment including tattoo removal, perfluorodecalin is used to inhibit or resolve whitening, for example to speed a laser therapy session. 18-. (canceled)9. A method comprising promoting optical effectiveness using a chemical facilitator proximate a phototherapy treatment area below a skin surface.10. The method of claim 9 , wherein the chemical facilitator includes perfluorodecalin.1112-. (canceled)13. The method of claim 9 , wherein promoting optical effectiveness includes reducing whitening.14. The method of claim 9 , wherein promoting optical effectiveness includes preventing whitening.15. The method of claim 9 , wherein promoting optical effectiveness includes having a time interval between two consecutive phototherapy passes of less than about 20 minutes.16. A treatment method including a step of providing perfluorodecalin proximate a phototherapy treatment area including a benign pigmented lesion.17. The method of claim 16 , wherein the benign pigmented lesion is a tattoo.18. The method of claim 16 , wherein the step includes delivering perfluorodecalin from a single-patient-use claim 16 , disposable device.19. The method of claim 18 , wherein the device is a patch.20. The method of claim 18 , wherein the device is a pre-filled applicator.21. The method of claim 18 , wherein the device is a swab.22. The method of claim 18 , wherein the device is substantially transparent to a laser output.23. A skin treatment method claim 18 , including: (a) exposing to a light output a skin portion including a condition treatable in whole or in part with light; and (b) providing an amount of a chemical facilitator sufficient to provide a result-effective event against a ...

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Номер записи: 33
27-06-2013 дата публикации

TOILET PAPER USING POLYMERIC MATERIALS

Номер: US20130165874A1
Автор: Miroshnichenko Vladimir Vitalievich, Pilkin Vitaly Evgenievich
Принадлежит:

The invention can be used to produce environmentally friendly toilet paper in which the use of natural materials such as paper and/or cellulose and/or cotton is reduced. The essence of the first embodiment of the invention: the toilet paper using polymeric materials is a sheet made of at least one polymeric material and/or at least one material containing at least one polymeric material, herewith at least one side of specified sheet is coated completely or partially by material or material comprising paper and/or cellulose and/or cotton, herewith at least one polymeric material used in specified toilet paper is completely or partially water-soluble. The essence of the second embodiment of the invention: in the toilet paper using polymeric materials a part of a side of toilet paper sheet is coated with polymeric material and/or material containing polymeric material. 1. A toilet paper using polymeric materials wherein a toilet paper is a sheet made of at least one polymeric material and/or at least one material containing at least one polymeric material , herewith at least one side of specified sheet is coated completely or partially by material or material comprising paper and/or cellulose and/or cotton (hereinafter material or material comprising paper and/or cellulose and/or cotton referred to as “natural material”) , herewith at least one polymeric material used in specified toilet paper is completely or partially water-soluble.2. The toilet paper according to claim 1 , wherein side of toilet paper sheet coated with natural material has two sectors: central sector and outer sector claim 1 , herewith: a) the central sector is coated with natural material claim 1 , while the outer sector is not coated with natural material claim 1 , or b) the central sector and outer sector are coated with natural material claim 1 , herewith according to “a” and “b” the outer sector of toilet paper sheet surrounds the central sector of toilet paper sheet in whole or in part.3. The ...

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Номер записи: 34
27-06-2013 дата публикации

TRANSDERMAL ABSORPTION PREPARATION

Номер: US20130165875A1
Автор: Choi Young Kweon, Kim Jung Ju, Kim Seong Su, Lee Jung Sik, Park Seong Min
Принадлежит: ICURE Pharmaceutical Inc.

The present, invention relates to a transdermal absorption preparation. The transdermal absorption preparation of the present invention comprises a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant, and a transdermal absorption promoter. Also, the present invention provides a transdermal absorption preparation comprising a drug-containing adhesive layer, a drug-protective layer, and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, acrylic rubber, an anti-crystallisation agent, and a transdermal absorption promoter. When the transdermal absorption preparation of the present invention is used for the treatment of Parkinson's disease or restless leg syndrome, no side effect due to an increase in the initial drug concentration in blood occurs and the skin penetration effect of the drug is excellent. 1. A transdermal absorption preparation , comprising:a drug-containing adhesive layer;a drug-protective layer; anda release layer, wherein the drug-containing adhesive layer includes ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant and a transdermal absorption, promoter.2. A transdermal absorption preparation , comprising:a drug-containing adhesive layer;a drug-protective layer; anda release layer, wherein the drug-containing adhesive layer includes ropinirole or a salt thereof, an acrylic adhesive, an anti-crystallization agent and a transdermal absorption promoter.3. The transdermal absorption preparation of claim 1 , further comprising a support layer.4. The transdermal absorption preparation of claim 1 , wherein the ropinirole or the salt thereof is included in an amount of 5˜30 wt % based on a total amount of the drug-containing adhesive layer.5. The transdermal absorption preparation of claim 1 , wherein the rubber is at least ...

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Номер записи: 35
04-07-2013 дата публикации

Apparatus for Enhancing Wound Healing

Номер: US20130172833A1
Автор: Vitaris Ronald F.
Принадлежит: TYCO HEALTHCARE GROUP LP

A wound therapy apparatus for enhancing healing of a wound includes a wound dressing configured for placement over the wound to define a reservoir over the wound in which a wound contact fluid may be maintained by forming a substantially fluid-tight seal around the wound. An elastic bladder member defined by or within the wound dressing is expandable to exert a pressure on the wound contact fluid within the reservoir. A fluid system is in fluid communication with the reservoir for selectively delivering the wound contact fluid to the reservoir, and a pressure system is in fluid communication with the bladder member for delivering a compressed liquid or gas to the bladder member to effect expansion in the bladder member. 1. A wound therapy apparatus for enhancing healing of a wound , comprising:a wound dressing configured for placement over a wound to define a reservoir over the wound in which a wound contact fluid may be maintained by forming a substantially fluid-tight seal around the wound;an elastic bladder member defined by or within the wound dressing, the elastic bladder member expandable to exert a pressure on the wound contact fluid within the reservoir;a fluid system in fluid communication with the reservoir for selectively delivering the wound contact fluid to the reservoir; anda pressure system in fluid communication with the bladder member for delivering a compressed liquid or gas to the bladder member to effect expansion in the bladder member.2. The apparatus according to claim 1 , wherein the elastic bladder member is coupled to a substantially inelastic backing layer and the backing layer is coupled to a body attachment layer for contacting the skin around the wound such that expansion of the bladder member may effect a tension in backing layer to the draw the skin around the wound inwardly.3. The apparatus according to claim 2 , wherein the elastic bladder is coupled to the substantially inelastic backing layer by an inner adhesive ring nested within ...

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Номер записи: 36
25-07-2013 дата публикации

MEDICAL APPLICATOR DEVICE

Номер: US20130190702A1
Автор: Barofsky Andrew, Longo Paul, Phillips Wayne
Принадлежит:

Embodiments provide a medical device in the form of an applicator for applying a medical composition to a patient. The applicator includes a body, a tip, and a delivery mechanism. The body defines a storage chamber for the medical composition and has an opening for deploying the medical composition from the storage chamber. The tip covers the opening and has a closed state wherein the tip maintains the medical composition in the storage chamber and an open state wherein the medical composition can be deployed through the opening and the tip. 1. An applicator device , comprising:a body having a storage chamber for holding a composition, the storage chamber having an opening; anda delivery mechanism for dispensing the composition from the storage chamber through the opening in response to actuation by a user, the delivery mechanism comprising a delivery mechanism that is moveable between a compact position for storage and transport and a cocked position for deployment of the composition from the applicator.2. The applicator device of claim 1 , further comprising a tip at least partially covering the opening and maintaining the composition within the storage chamber.3. The applicator device of claim 1 , wherein the tip has a closed state in which the composition is maintained within the storage chamber and an open state in which the composition can be dispensed through the opening and the tip.4. The applicator device of claim 1 , further comprising the composition.5. The applicator device of claim 4 , wherein claim 4 , in both the compact position and the cocked position claim 4 , the composition is maintained in the storage chamber.6. The applicator device of claim 1 , wherein the delivery mechanism is a telescoping delivery mechanism.7. The applicator device of claim 6 , wherein the telescoping delivery mechanism includes a piston located within the storage chamber claim 6 , the piston configured to move the composition in the storage chamber through the opening as ...

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Номер записи: 37
08-08-2013 дата публикации

APPLICATOR FOR DISPENSING A SURGICAL PREP SOLUTION

Номер: US20130202482A1
Автор: Froimson Mark I.
Принадлежит: THE CLEVELAND CLINIC FOUNDATION

An applicator for delivering a surgical prep solution onto a bodily surface includes a hollow member having a reservoir, an absorbent pad that is attached to a portion of the hollow member and in communication with the reservoir, a timer operably connected to the hollow member, and a gating mechanism in electrical communication with the timer and for coordinating application of the surgical prep solution with activation of the timer. 1. An applicator for dispensing a surgical prep solution onto a bodily surface , said applicator comprising:a hollow member including a reservoir;an absorbent pad attached to a portion of said hollow member, said absorbent pad being in fluid communication with said reservoir;a timer operably connected to said hollow member; anda gating mechanism for coordinating application of the surgical prep solution with activation of said timer, said gating mechanism being in electrical communication with said timer.2. The applicator of claim 1 , wherein said timer is physically integrated with a portion of said hollow member.3. The applicator of claim 1 , wherein said timer is capable of generating at least one signal.4. The applicator of claim 1 , wherein said at least one signal comprises an audible signal or a visible signal.5. The applicator of claim 1 , wherein release of the surgical prep solution from said reservoir is prevented until said timer is activated.6. The applicator of claim 4 , wherein said timer generates an audible and/or visible signal upon application of the surgical prep solution onto the bodily surface for a period of time sufficient to allow evaporation of the surgical prep solution from the bodily surface.7. The applicator of claim 4 , wherein said timer generates an audible and/or visible signal after a period of time sufficient to allow evaporation of the surgical prep solution from the bodily surface.8. The applicator of claim 1 , further including a communication protocol configured to communicate with an electronic ...

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Номер записи: 38
08-08-2013 дата публикации

Antiseptic Applicators and Packaging Techniques

Номер: US20130202483A1
Автор: Tennican Patrick O.
Принадлежит: HYPROTEK, INC.

This disclosure describes example antiseptic applicators that may be used in combination with one or more cleansing, antimicrobial and/or antiseptic agents to reduce or eliminate contaminates on a surface. According to some embodiments, the disclosure describes that the applicators may contain an impermeable layer and a permeable layer, where the impermeable layer prevents contaminates for transferring from a user's hand to the permeable layer and the surface. 1. A medical applicator comprising:an impermeable layer, the impermeable layer having an outer surface configured to interface with a user;a permeable, absorbent layer having a top face coupled to the impermeable layer and a bottom face to interface with a surface; anda cleansing, antimicrobial or antiseptic agent disposed within and carried by the permeable, absorbent layer.2. The medical applicator of claim 1 , wherein the impermeable layer comprises polyethylene claim 1 , silicon oxide coated polymeric films claim 1 , polypropylene claim 1 , polysilicone claim 1 , polytetrafluoroethylene claim 1 , polyvinyl chloride claim 1 , mylar claim 1 , or a mixture thereof3. The medical applicator of claim 2 , wherein the outer surface of the impermeable layer has a ridged texture claim 2 , a lined texture claim 2 , a dotted texture claim 2 , a reticulated texture or a combination thereof4. The medical applicator of claim 1 , wherein the permeable claim 1 , absorbent layer comprises starch polymer claim 1 , cellulosic gel claim 1 , polyethylene foam claim 1 , polyurethane foam claim 1 , silicone open cell foam claim 1 , or mixtures thereof.5. The medical applicator of claim 1 , wherein the bottom face of the permeable claim 1 , absorbent layer has a rough texture claim 1 , a coarse texture claim 1 , a smooth texture claim 1 , a micro texture claim 1 , a nano texture claim 1 , or a combination thereof configured to scrub the material.6. The medical applicator of claim 1 , wherein the cleansing claim 1 , antimicrobial ...

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Номер записи: 39
08-08-2013 дата публикации

Topical Foam Composition

Номер: US20130202654A1
Автор: LULLA Amar, MALHOTRA Geena, Purandare Shrinivas Madhukar
Принадлежит: CIPLA LIMITED

A topical foam pharmaceutical composition for rectal administration comprising rifaximin in the form of nanosized particles is described. Also described is a method of making the composition and the use of the composition to as a medicament. 1. A pharmaceutical composition for topical rectal administration in the form of a foam , the composition comprising rifaximin in the form of nanoparticles.2. A composition according to claim 1 , further comprising an aqueous or non-aqueous vehicle.3. A composition according to claim 2 , comprising wherein the non-aqueous vehicle is one or more pharmaceutically acceptably alkanols; one or more pharmaceutically acceptable vegetable oils; or one or more pharmaceutically acceptable organic esters.4. A composition according to claim 3 , wherein the water soluble alkanol is ethanol; propylene glycol; glycerol; polyethylene glycol; polypropylene glycol; propylene glycol; a glyceryl ester; or a mixture thereof.5. A composition according to claim 2 , wherein the vehicle comprises a water soluble alkanol and water claim 2 , and wherein the w/w ratio of the water soluble alkanol to water from 0.05:10 to 10:0.05.6. A composition according to claim 2 , wherein the vehicle constitutes from 10% w/w to 90% w/w of the total weight of the composition.7. A composition according to claim 2 , wherein the vehicle comprises water in an amount from 20% w/w to 90% w/w of the total weight of the composition claim 2 , and a water-soluble alkanol in an amount from 0% w/w to 50% w/w of the total weight of the composition.8. A composition according to claim 1 , further comprising at least one surfactant.9. A composition according to claim 8 , wherein the surfactant is present in an amount of from 0.1 to 1.0 w/w of the total weight of the composition.10. A composition according to claim 1 , further comprising at least one propellant.11. A composition according to claim 10 , wherein the propellant is present in an amount from 2 to 20% w/w of the total weight ...

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Номер записи: 40
08-08-2013 дата публикации

SYSTEMS AND METHODS FOR DELIVERING FLUID TO A WOUND THERAPY DRESSING

Номер: US20130204210A1
Автор: BEASLEY MIKE, Coulthard Richard Daniel John, Evans Daniel, FLOWER KINGSLEY ROBERT GEORGE, Pratt Benjamin A.
Принадлежит:

Provided are systems and methods for delivery of fluid to a wound therapy dressing. In exemplary embodiments, a pressure source provides negative pressure to a wound dressing and a biasing mechanism provides positive pressure to a fluid reservoir. 1. A system adapted to deliver fluid to a wound therapy dressing , comprising:a negative pressure source adapted to be in fluid communication with the wound therapy dressing to provide negative pressure to the wound therapy dressing;a housing adapted to receive a fluid reservoir, the fluid reservoir adapted to be in fluid communication with the wound therapy dressing to provide fluid from the fluid reservoir to the wound therapy dressing;a biasing mechanism adapted to secure the fluid reservoir in the housing and to exert a positive pressure on the fluid in the fluid reservoir; anda control circuit adapted to control the negative pressure in the wound therapy dressing.2. The system of claim 1 , wherein the negative pressure source is disposed within the housing.3. The system of claim 1 , wherein the biasing mechanism is configured to compress the fluid reservoir to secure the fluid reservoir within the housing and to exert the positive pressure on the fluid in the fluid reservoir.4. The system of claim 1 , wherein the biasing mechanism is a spring.5. The system of claim 4 , wherein the spring is a constant-force spring.6. The system of claim 1 , wherein the positive pressure exerted on the fluid in the fluid reservoir is at least approximately 75 mm Hg.7. The system of claim 1 , wherein the fluid reservoir is a polyethylene bag.8. The system of claim 1 , wherein the control circuit is configured to control a flow of the fluid from the fluid reservoir to the wound therapy dressing and to detect a flow rate of the fluid from the fluid reservoir to the wound therapy dressing.9. The system of claim 8 , wherein the control circuit is coupled to a flow sensor configured to detect the flow rate of the fluid from the fluid ...

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Номер записи: 41
08-08-2013 дата публикации

Adhesive Patch with Antimicrobial Composition

Номер: US20130204212A1
Автор: Patrick O. Tennican
Принадлежит: Hyprotek Inc

This disclosure describes example adhesive medical patches that may be used in combination with one or more antimicrobial agents to create and/or maintain an area of human skin that is free from contaminants. According to some embodiments, the disclosure describes that the adhesive patches may contain an adhesive material affixed to the perimeter of an impermeable backing According to some embodiments, the adhesive patch may also have a permeable layer containing an antimicrobial agent located interior to the adhesive material on the impermeable backing.

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Номер записи: 42
15-08-2013 дата публикации

WOUND THERAPY DEVICE

Номер: US20130211318A1
Автор: Croizat Pierre, Eckstein Axel
Принадлежит: Paul Hartmann AG

Wound therapy device for the treatment of wounds by means of negative pressure and fluid irrigation, includes a negative-pressure dressing, a pressure sensor which can generate pressure measurement values in order to determine the negative pressure present in the negative-pressure dressing, a drainage container for collecting liquid, and a drainage line by means of which liquid can be conveyed from the negative-pressure dressing into the drainage container. The device can further include a first pump unit for aspirating liquid from the wound space via the drainage line, an instillation container for making available an instillation fluid, an instillation line. Instillation fluid can be delivered from the instillation container into the wound space. 120405060. Wound therapy device ( , , , ) for the treatment of wounds by means of negative pressure and fluid irrigation , comprising{'b': '15', 'i. a negative-pressure dressing () with a fluid-tight cover, such that a wound space can be formed between the cover and the wound base,'}{'b': 2', '2, 'ii. a pressure sensor means (), which can generate pressure measurement values, wherein the pressure sensor means () is in fluidic communication with the wound space,'}{'b': '1', 'iii. a drainage container () for collecting liquid,'}{'b': 3', '1, 'iv. a drainage line () by means of which liquid can be conveyed from the wound space into the drainage container (),'}{'b': 4', '3', '4', '1, 'v. a first pump unit () for aspirating liquid from the wound space via the drainage line (), wherein the first pump unit () is connected in a fluid-conducting manner to the drainage container (),'}{'b': '7', 'vi. an instillation container () for making available an instillation fluid,'}{'b': 8', '7, 'vii. an instillation line () by means of which instillation fluid can be delivered from the instillation container () into the wound space,'}{'b': '7', 'viii. a means for delivering an instillation fluid from the instillation container () into the ...

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Номер записи: 43
15-08-2013 дата публикации

SYSTEMS AND METHODS FOR DELIVERING FLUID TO A WOUND THERAPY DRESSING

Номер: US20130211348A1
Автор: Bendele Kevin W., Kazala Richard Marvin, Randolph Larry Tab
Принадлежит:

Provided are systems and methods for delivery of fluid to a wound therapy dressing. In exemplary embodiments, a pressure source provides negative pressure to a wound dressing and positive pressure to an actuator that expels fluid from a fluid reservoir. 1. A system for delivering fluid to a wound therapy dressing , the system comprising:an actuator configured to engage a fluid reservoir, the actuator adapted to expel fluid from the fluid reservoir, wherein the fluid reservoir is adapted to be in fluid communication with the wound therapy dressing;a pressure source configured to provide positive pressure to the actuator and negative pressure to the wound therapy dressing; anda fluid control device adapted to control fluid communication between the fluid reservoir and the wound therapy dressing.2. The system of claim 1 , wherein the actuator is a compression sleeve positioned circumferentially about the fluid reservoir claim 1 , the compression sleeve adapted to compress the fluid reservoir and to expel fluid from the fluid reservoir upon application of the positive pressure.3. The system of claim 1 , wherein the actuator is an expandable bladder positioned within the fluid reservoir claim 1 , the expandable bladder adapted to expand upon application of the positive pressure to displace the fluid in the fluid reservoir and to expel the fluid from the fluid reservoir.4. The system of claim 1 , wherein the fluid control device comprises a control valve and a metering flow orifice claim 1 , wherein the control valve and the metering flow orifice cooperate to provide a volume of the fluid from the fluid reservoir according to the positive pressure provided to the actuator and a size of the metering flow orifice.5. The system of claim 4 , wherein the control valve is selected from the group consisting of a solenoid valve and a solenoid-actuated pinch valve.6. The system of claim 1 , wherein the fluid control device comprises a control valve selected from the group ...

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Номер записи: 44
15-08-2013 дата публикации

FOAM STRUCTURE WOUND INSERTS FOR DIRECTIONAL GRANULATION

Номер: US20130211349A1
Автор: Robinson Timothy Mark, Stokes Benjamin
Принадлежит:

A wound treatment system comprises a wound-treatment apparatus and a wound dressing coupled to the apparatus. The wound dressing includes a foam structure wound insert having pores with a greater cross-sectional area when viewed from a first direction and a smaller cross-sectional area when viewed from an orthogonal direction. Methods for making such wound inserts may include compressing foam structure material having pores with a substantially uniform cross-sectional area. Methods for treating a wound using a wound insert. 1. A wound insert for use with a wound dressing , the wound insert comprising:a foam structure having a first surface, a second surface generally parallel to the first surface, and a third surface extending between the first surface and the second surface; anda plurality of pores distributed through the foam structure in an open-cell relation forming flow channels for receiving and distributing fluid to a wound, each pore of the plurality of pores having a first cross-sectional area parallel to the first surface and a second cross-sectional area perpendicular to the first surface wherein the first cross-sectional area of most of the pores is greater than the second cross-sectional area of the pores.2. The wound insert of wherein the third surface is substantially perpendicular to the first and second surfaces.3. The wound insert of wherein the wound insert is substantially rectangular in shape.4. The wound insert of wherein the first surface comprises a plurality of channels.5. The wound insert of wherein the channels are approximately 1.0 mm wide.6. The wound insert of wherein the second surface is adapted to receive fluids from a source of fluid and the first surface is adapted to be disposed proximate the wound for distributing the fluids to the wound.7. The wound insert of further comprising indicia positioned on the third surface indicating the correct orientation of the wound insert within the wound.8. The wound insert of claim 1 , where ...

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Номер записи: 45
15-08-2013 дата публикации

Spreading implement

Номер: US20130211350A1
Автор: Adam Charles Watkinson, Magnus Ahlstrom, Mark Simon Bayly, Peter Bayly
Принадлежит: Acrux DDS Pty Ltd

This invention relates to an implement 1 for applying a volume of liquid to a treatment surface. The implement includes a support means 3 onto which is mounted a receptacle 2 , the receptacle defining a reservoir space 4 which receives the liquid. The receptacle includes a wall 6 having a working surface that is used to spread the liquid over the treatment surface. The wall 6 is resiliently deformable so in use the working surface maintains contact with the treatment surface when spreading the liquid. The implement has a specific application in applying a transdermal lotion to the axilla area of the user. The invention also relates to a system for transdermal administration of a physiological active agent from a liquid composition and a method of conducting the same.

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Номер записи: 46
15-08-2013 дата публикации

PERCUTANEOUS ABSORPTION TYPE FORMULATION

Номер: US20130211353A1
Автор: KURITA Hisakazu, Toshimitsu Arata
Принадлежит: HISAMITSU PHARMACEUTICAL CO., INC.

Provided is a percutaneous absorption type formulation of a drug such as imidafenacin and silodosin, wherein stable absorption through the skin is realized. The percutaneous absorption type formulation containing a drug such as imidafenacin and silodosin further contains a transdermal absorption promoting agent, and fatty acid ester and/or fatty acid amide that further improve(s) the function of the transdermal absorption promoting agent. 1. A percutaneous absorption preparation comprising a drug and one or more percutaneous absorption promoting agents selected from triacetin , isopropyl myristate , oleyl alcohol , octyldodecanol and stearyl alcohol for said drug , wherein the percutaneous absorption preparation further comprises a fatty acid ester and/or a fatty acid amide that further improve the function of the percutaneous absorption promoting agents.2. The percutaneous absorption preparation according to claim 1 , wherein the drug is imidafenacin and/or a salt thereof claim 1 , or silodosin and/or a salt thereof.3. The percutaneous absorption preparation according to claim 1 , wherein the fatty acid ester is sorbitan monolaurate.4. The percutaneous absorption preparation according to claim 1 , wherein the fatty acid amide is lauric acid diethanolamide.5. The percutaneous absorption preparation according to claim 1 , which is a skin external patch that comprises a pressure-sensitive adhesive composition comprising:(1) imidafenacin and/or a salt thereof, or silodosin and/or a salt thereof, as a drug,(2) triacetin,(3) sorbitan monolaurate and/or lauric acid diethanolamide,(4) a pressure-sensitive adhesive base.6. The percutaneous absorption preparation according to claim 1 , which is a skin external patch that comprises a pressure-sensitive adhesive composition comprising:(1) imidafenacin and/or a salt thereof as a drug,(2) triacetin, isopropyl myristate, oleyl alcohol, octyldodecanol, or stearyl alcohol,(3) sorbitan monolaurate,(4) a pressure-sensitive adhesive ...

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Номер записи: 47
22-08-2013 дата публикации

DEVICES AND METHODS FOR DELIVERY OF AGENTS TO BIOLOGICAL TISSUE

Номер: US20130218104A1
Автор: Smith Stephen J.
Принадлежит:

Described herein are systems, apparatuses, and methods that employ a medical device to augment delivery of an agent to biological tissue. The medical device includes a reservoir containing the agent, a release port, and sealable base that can be attached to the biological tissue so that the agent is held under pressure upon attachment. The device can only release the agent through the release port. A penetrating instrument can be utilized to augment delivery of the agent to the biological tissue. 1. A medical device , comprising:a reservoir configured to hold an agent, the reservoir comprising a release port that facilitates delivery of the agent to a biological tissue and an impermeable portion that is impermeable to release of the agent; anda sealable base connected to the reservoir, the sealable base comprising an attachment mechanism that facilitates an attachment to the biological tissue.2. The medical device of claim 1 , wherein the attachment mechanism is capable of rapid attachment to the biological tissue and removal from the biological tissue.3. The medical device of claim 1 , wherein the reservoir holds the agent prior to the attachment to the biological tissue.4. The medical device of claim 1 , wherein the agent has a medical application.5. The medical device of claim 1 , wherein the release port comprises a structural element to retain the agent in the reservoir prior to the attachment to the biological tissue.6. The medical device of claim 1 , wherein the impermeable portion comprises an injection port that facilitates filling claim 1 , refilling claim 1 , or emptying the reservoir while the medical device is attached to the biological tissue.7. The medical device of claim 7 , wherein the injection port is covered by a material that allows penetration with a penetrating instrument.8. The medical device of claim 8 , wherein the injection port is self-sealing upon removal of the penetrating instrument.9. The medical device of claim 1 , wherein the ...

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Номер записи: 48
29-08-2013 дата публикации

MEDICINAL ROLLER BALL APPLICATORS, ASSOCIATED PHARMACEUTICAL COMPOSITIONS, AND THEIR USE TO TREAT AFFLICTED SKIN TISSUES

Номер: US20130226107A1
Автор: Fields Stephen Craig
Принадлежит: LEXINGTON PHARMACEUTICALS LABORATORIES, LLC

The present invention discloses a novel medicinal roller ball applicator, comprising a ball with a rough surface, which can relatively painlessly facilitate the application and therapeutic massage of an active ingredient into a sensitive infected area of tissue for prolonged periods of time, while simultaneously removing dead epidermal tissue, a proven harrier to adsorption and penetration of active ingredients to the desired lower living skin tissue. 1. A method for treating afflicted skin tissue b massaging an effective dose of an active ingredient into the tissue with a medical roller ball applicator which simultaneously dispenses a pharmaceutical composition comprising the active ingredient: wherein the applicator comprises a reservoir containing the pharmaceutical composition in contact with a revolving ball fitted to an end of the reservoir.2. The method according of claim 1 , wherein the surface of the bail is smooth.3. The method of claim 1 , wherein the surface of the ball is either rough or non-smooth.4. The method of claim 3 , wherein die rough or non-smooth surface is due to surface imperfections which alter the outer epidermal layer of the skin without creating an abrasion as the ball is rolled across the afflicted skin tissue during massage.5. The method of claim 3 , wherein the ball causes micro-perforations in the skin surface at the cellular level without grossly and painfully abrading claim 3 , away the surface of the skin.6. The method according to claim 3 , wherein the ball lifts dead skin cells to expose the live lower epidermal layer.7. The method of claim 3 , wherein the rough or non-smooth surface has a coarseness corresponding to a sandpaper grit of 60-1600.8. The method of claim 1 , wherein the pharmaceutical composition comprises one or more active ingredients selected from: antivirals claim 1 , antibiotics claim 1 , antibacterials claim 1 , antifungals claim 1 , anesthetics claim 1 , anti-microbials and antivenoms.9. The method according ...

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Номер записи: 49
29-08-2013 дата публикации

PERCUTANEOUS ABSORBENT AND ADHESIVE SHEET FOR SKIN PATCH

Номер: US20130226112A1
Автор: Akazawa Mitsuji, Yamasaki Keiko
Принадлежит:

The invention provides an adhesive sheet for adhesion to the skin, as well as a transdermal absorption preparation containing the adhesive sheet and a drug or a pharmaceutically acceptable salt thereof in the adhesive layer of the adhesive sheet. The adhesive sheet comprises a support and an adhesive layer formed on the support, wherein the adhesive layer contains at least a thermoplastic elastomer, and more than 300 parts by weight of liquid paraffin per 100 parts by weight of the elastomer, and wherein the adhesive layer contains not more than 10 wt % of a tackifier. 1. An adhesive sheet for adhesion to the skin , which comprises a support and an adhesive layer formed on the support , wherein the adhesive layer comprises a thermoplastic elastomer , and more than 300 parts by weight of liquid paraffin per 100 parts by weight of the elastomer , and optionally comprises not more than 10 wt % of a tackifier.2. The adhesive sheet according to claim 1 , wherein the content of the liquid paraffin in the adhesive layer is not less than 60 wt %.3. The adhesive sheet according to claim 1 , wherein the thermoplastic elastomer is a styrene-based block copolymer.4. The adhesive sheet according to claim 3 , wherein the styrene-based block copolymer is a styrene-isoprene-styrene copolymer.5. The adhesive sheet according to claim 1 , wherein the adhesive layer does not contain a tackifier.6. (canceled)7. The adhesive sheet according to claim 2 , wherein the adhesive layer does not contain a tackifier.8. The adhesive sheet according to claim 3 , wherein the adhesive layer does not contain a tackifier.9. The adhesive sheet according to claim 4 , wherein the adhesive layer does not contain a tackifier.10. The adhesive sheet according to claim 2 , wherein the thermoplastic elastomer is a styrene-based block copolymer.11. The adhesive sheet according to claim 10 , wherein the adhesive layer does not contain a tackifier.12. The adhesive sheet according to claim 10 , wherein the styrene ...

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Номер записи: 50
29-08-2013 дата публикации

UV STABLE TRANSDERMAL THERAPEUTIC PLASTER WITH A UV ABSORBING ADHESIVE LAYER SEPARATED FROM THE DRUG MATRIX

Номер: US20130226113A1
Автор: Dittgen Michael, Ingwersen Jan-Peter, Kaffl Hubert, LANGGUTH Thomas, Mletzko Stephan, Schenk Dirk, SCHUMACHER Jochen, Suesse Manfred
Принадлежит: Bayer Pharma AG

The invention relates to a UV stable transdermal therapeutic system (TTS) consisting of a back layer, at least one matrix containing an active substance and optionally, a withdrawal film and an UV-radiation absorber. An adhesive layer containing said UV-radiation absorber is arranged between the back layer and the matrix containing an active substance which is distant as much as possible from a surface, a separation layer is arranged between the adhesive layer containing said UV-radiation absorber and the matrix containing an active substance, which is as remote as possible from the surface which is impermeable to the active substance and UV-radiation absorber. The inventive transdermal therapeutic system exhibits a high stability and is devoid of inconveniences of existing TTS containing a light-sensitive substance. 1. Transdermal therapeutic system (TTS) consisting of a backing layer , of at least one active ingredient-containing matrix and optionally of a detachable sheet , and comprising a UV absorber , characterized in thatat least one UV absorber-containing adhesive layer is provided between the backing layer and the active ingredient-containing matrix which is furthest away from the surface of the skin,at least one separating layer which is impermeable to active ingredient and impermeable to the UV absorber is present between the adhesive layer containing the UV absorber and the active ingredient-containing matrix which is furthest away from the surface of the skin.2. Transdermal therapeutic system according to claim 1 , characterized in that the sequence of layers in the system starting from the side facing away from the skin is backing layer claim 1 , UV absorber-containing adhesive layer claim 1 , separating layer and finally a mono- or bilayer active ingredient-containing matrix whose pressure-sensitive adhesive surface is covered by a detachable protective sheet.3. Transdermal therapeutic system according to claim 1 , characterized in that the weight per ...

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Номер записи: 51
05-09-2013 дата публикации

METHOD OF TREATING SKIN

Номер: US20130231618A1
Автор: Kemp Helen Rochelle, VANOOSTHUYZE Kristina Emma Inge, ZUPKOSKY Pamela Joan
Принадлежит: THE GILLETTE COMPANY

A method of treating post-shave irritation via an advanced shave regimen. 2. The method of claim 1 , wherein said first composition is applied to said portion of skin for a contact time of at least about 5 seconds.3. The method of claim 1 , wherein said pre-treatment composition comprises at least one of a facial wash claim 1 , a pre-shave scrub claim 1 , and a pre-shave oil claim 1 , and wherein said step of applying said pre-treatment composition also includes a step of washing off said pre-treatment composition to form said prepared skin.4. The method of claim 1 , wherein said first composition comprises at least one of a shave foam claim 1 , a post foaming shave gel claim 1 , a non-aerosol shave gel claim 1 , a personal cleanser claim 1 , and a shave oil.5. The method of claim 1 , wherein said second composition is a post shave composition such as a balm or moisturizer.6. The method of claim 5 , wherein said second composition is not washed off.7. The method of claim 1 , wherein daily basis refers to within a 48 hour period.8. The method of claim 1 , further comprising a step of identifying a subject susceptible at least one of nicks and cuts claim 1 , post shave itching claim 1 , and pseudofolliculitis barbae claim 1 , and wherein said portion of skin is from said subject.9. The method of claim 1 , wherein said portion of skin is selected from the group consisting of facial hair claim 1 , beard/neck hair claim 1 , scalp claim 1 , underarm claim 1 , and bikini area.10. The method of claim 1 , wherein said portion of skin is from a subject susceptible to mild or moderate pseudofolliculitis barbae.11. The method of claim 1 , further comprising a step diagnosing a subject having mild to moderate post-shave irritation.12. The method of claim 11 , wherein said step of visually diagnosis is performed visually or by an optical diagnostic machine using stereo or confocal imaging technology.13. The method of claim 1 , further comprising a step of reducing the occurrence ...

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Номер записи: 52
05-09-2013 дата публикации

Wound Management Device

Номер: US20130231619A1
Автор: Davison Eric, Wiltshire Neil
Принадлежит: SALTS HEALTHCARE LIMITED

A wound management device comprising at least one wall element of flexible sheet material, the device being securable to skin around a wound site to define a space wherein the wound is accessible; and a connector element held to the at least one wall element and affording at least one passage for external communication with the space; wherein the connector element includes at least one formation through which the or a passage extends, for engagement by a member for fluid supply to or removal from the space. 1. A wound management device comprising at least one wall element of flexible sheet material , the device being securable to skin around a wound site to define a space wherein the wound is accessible; and a connector element held to the at least one wall element and affording at least one passage for external communication with the space; wherein the connector element includes at least one formation through which the or a passage extends , for engagement by a member for fluid supply to or removal from the space.2. A wound management device according to comprising first and second wall elements of flexible sheet material claim 1 , secured to one another to define a space therebetween claim 1 , a first one of said wall elements being adapted for adhesive securement to skin around a wound site and being provided or being able to be provided with an opening for access between the wound site and the space between the wall elements; the connector element being held to at least one of the wall elements and the at least one passage afforded thereby providing for external communication with the space between the wall elements.3. A wound management device according to wherein the or each formation comprises a tubular spigot through which the respective passage extends.4. A wound management device according to wherein the connector element comprises a body secured to the wall elements by being received and held between respective neck portions thereof.5. A wound management ...

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Номер записи: 53
19-09-2013 дата публикации

WOUND TREATMENT APPARATUSES AND METHODS FOR CONTROLLED DELIVERY OF FLUIDS TO A WOUND

Номер: US20130245580A1
Автор: Locke Christopher Brian, Whyte David George
Принадлежит: KCI Licensing, Inc.

Pump cassettes, wound-treatment apparatuses and methods. In some embodiments, a pump cassette comprises: a pump body having a pump chamber, an inlet valve in fluid communication with the pump chamber, and an outlet valve in fluid communication with the pump chamber; a diaphragm coupled to the pump body such that the diaphragm is movable to vary a volume in the pump chamber; and an identifier configured to store one or more properties of the pump cassette such that the identifier is readable by an automated reader to determine the one or more properties. In some embodiments, the pump cassette is configured to be removably coupled to a wound-treatment apparatus having an actuator such that the actuator can be activated to move the diaphragm. 1. A pump cassette for use with a wound-treatment apparatus , comprising:a pump body having a chamber with a variable volume, an inlet valve in fluid communication with the pump chamber and adapted to receive fluid from a fluid container, and an outlet valve in fluid communication with the chamber and adapted to deliver the fluid to a wound;a diaphragm movably coupled to the pump body to vary the volume of the chamber in response to a mechanical force; andan identifier configured to store information relating to the pump cassette, the identifier being readable to provide the information;wherein the pump cassette is configured to be removably coupled to the wound-treatment apparatus and adapted to receive a signal from the wound-treatment apparatus to provide the mechanical force to the diaphragm.2. The pump cassette of claim 1 , wherein the identifier comprises at least one of a radio-frequency identification (RFID) tag claim 1 , a barcode claim 1 , or a magnetic stripe.3. The pump cassette of claim 2 , wherein the identifier is readable by an automated reader disposed in the wound-treatment apparatus.4. The pump cassette of claim 1 , wherein the identifier is a label.5. The pump cassette of claim 1 , wherein the information ...

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Номер записи: 54
26-09-2013 дата публикации

SYSTEM AND METHOD FOR THE TREATMENT OF LICE WITH A LIQUID SOLUTION

Номер: US20130253450A1
Автор: Shelton Laura Marie
Принадлежит:

The present invention relates generally to the treatment and eradication of lice. More particularly, the present invention relates to a system and method for treatment and eradication of lice through the submersion of an infected area in a liquid solution. 1. A system for the treatment of lice , said system comprising:a basin comprising a walled structure with a concave cavity configured to receive a lice treatment solution, wherein said lice treatment solution contains at least 95% ethyl alcohol.2. The system of claim 1 , wherein said walled structure of said basin further comprises a channel on one side configured to receive the neck of an individual to be treated.3. The system of claim 1 , wherein said lice treatment solution contains at least 0.05% bittering agent.4. The system of claim 1 , wherein said ethyl alcohol is at least 80 proof.5. The system of claim 1 , wherein said ethyl alcohol is 180 proof.6. The system of claim 1 , wherein said basin further comprises a timer.7. The system of claim 6 , wherein said timer is configured to produce a noticeable alert upon completion of a lice treatment.8. The system of claim 6 , wherein said timer is integrated into said walled structure of said basin.9. The system of claim 1 , wherein said basin further comprises a back rest portion configured to allow an individual to relax during receipt of a lice treatment session.10. A method for the treatment of lice claim 1 , said method comprising the steps of:filling a basin comprising a walled structure with a concave cavity with a lice treatment solution to a level appropriate for entirely engulfing all hair and scalp of an individual;submerging said hair and scalp of said individual into said basin for a period of not less than five minutes; andremoving said hair and scalp of said individual from said basin.11. The method of claim 10 , wherein said lice treatment solution contains at least 0.05% bittering agent.12. The method of claim 10 , wherein said ethyl alcohol is at ...

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Номер записи: 55
26-09-2013 дата публикации

Personal Care Product

Номер: US20130253452A1
Автор: KLOFTA Thomas James, LaVon Gary Dean, Schulte Thomas Edward
Принадлежит: The Procter & Gamble Company

A personal care product that includes a personal care composition disposed in a collapsible bag at least partially surrounded by an elastically deformable member and, optionally, an outer container body. The elastic member is constructed of an elastically extensible material that permits the transfer of infrared radiation through at least a portion of the elastic member. Potential energy is generated by stretching the elastically deformable member, which is used to dispense the composition in lieu of a propellant or pump. The container may also include a actuatable valve for dispensing the composition. 1) A personal care product for applying a personal care composition to skin in the form of a film without the use of an additional applicator , the personal care product comprising:(a) an outer container;(b) an at least partially expanded collapsible bag disposed in the outer container, an elastic member surrounding at least a portion of the collapsible bag such that the elastic member is stretched axially and radially, the elastic member being constructed of an elastically extensible material that permits the transfer of infrared radiation through at least a portion of the elastic member; and(c) a personal care composition disposed in the collapsible bag.2) The personal care product of claim 1 , wherein the composition includes at least one of a skin care composition claim 1 , an antifungal composition claim 1 , an antimicrobial composition claim 1 , a wound healing composition claim 1 , and an enzyme inhibiting composition.3) The personal care product of claim 2 , wherein the personal care composition includes a skin care composition and at least one active ingredient selected from the group consisting of zinc oxide claim 2 , petrolatum claim 2 , white petrolatum claim 2 , mineral oil claim 2 , cod liver oil claim 2 , lanolin claim 2 , dimethicone claim 2 , vitamin A claim 2 , palmitate claim 2 , allantoin claim 2 , calamine claim 2 , kaolin claim 2 , glycerin claim ...

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Номер записи: 56
10-10-2013 дата публикации

HOUSEHOLD MEDICATED-BATH TREATMENT DEVICE

Номер: US20130267890A1
Автор: LI JianHua
Принадлежит:

A medicine-bath treatment device includes a central basin having a seat thereabout, at least one fumigation opening and at least one air opening, an inner vessel for holding liquid in fluid communication with the at least one fumigation opening of the basin to provide fumigation steam to the basin from the inner vessel, a spray tube having an inlet in communication with the inner vessel and an outlet in the basin to provide a jet of heated liquid within the basin, and a fan having an outlet in communication with the at least one air opening to provide a stream of heated drying air within the basin. The device also include a heater, a temperature sensor for measuring ambient air temperature, and a controller operably connected to the pump, the fan, and the heater. The controller is operably programmed to automatically adjust at least one of a treatment temperature of the jet of heated liquid, a treatment temperature of the fumigation steam, and a treatment temperature of the heated drying air based on the ambient air temperature. 1. A medicine-bath treatment device comprising , in combination:a central basin having a seat thereabout, at least one fumigation opening and at least one air opening;an inner vessel for holding liquid in fluid communication with the at least one fumigation opening of the basin to provide fumigation steam to the basin from the inner vessel;a spray tube having an inlet in communication with the inner vessel and an outlet in the basin to provide a jet of heated liquid within the basin;a fan having an outlet in communication with the at least one air opening to provide a stream of heated drying air within the basin;a heater;a temperature sensor for measuring ambient air temperature;a controller operably connected to the pump, the fan, and the heater; andwherein the controller is operably programmed to automatically adjust at least one of a treatment temperature of the jet of heated liquid, a treatment temperature of the fumigation steam, and a ...

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Номер записи: 57
17-10-2013 дата публикации

POWDER DELIVERY DEVICE

Номер: US20130274690A1
Автор: Greenhalgh Paul, Schutte Eliane
Принадлежит: PROFIBRIX B.V.

Provided is a device for the dispensing of powders of the type in which a generated gas flow entrains the powder to be dispensed and carries the powder from the device via a barrel. The barrel has a bore including a main portion with a continuous internal surface, and is characterized in that the length of the main portion is at least fifteen times its maximum internal diameter; and/or the internal bore of the main portion is tapered; and/or the barrel has an outwardly flared outlet portion. 1. A device for the dispensing of powder comprising:a barrel having a bore including a main portion with a continuous internal surface through which a generated gas flow entrains the powder to be dispensed, wherein:a length of the main portion is at least fifteen times a maximum internal diameter of the bore; andthe barrel has an outwardly flared outlet portion.2. (canceled)3. (canceled)4. A device as claimed in claim 1 , wherein the internal bore of the main portion is tapered.5. A device as claimed in claim 1 , wherein the barrel is rigid.6. A device as claimed in claim 5 , wherein the length of the main portion of the barrel is at least eighteen times or at least twenty times the maximum internal diameter of the bore.7. A device as claimed in claim 5 , wherein the length of the main portion is between about 30 mm and 100 mm.8. A device as claimed in claim 5 , wherein the maximum internal diameter of the main portion is from 1 mm to 6 mm.9. A device as claimed in claim 1 , wherein the barrel is flexible.10. A device as claimed in claim 9 , wherein the main portion of the barrel has a length of between 50 mm and 300 mm.11. A device as claimed in claim 9 , wherein the internal diameter of the barrel is between 1 mm and 5 mm.12. A device as claimed in claim 9 , wherein the main portion of the barrel comprises a plastic tube.13. A device as claimed in claim 12 , wherein the barrel incorporates one or more malleable elongate members.14. A device as claimed in claim 13 , wherein the ...

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Номер записи: 58
24-10-2013 дата публикации

Applicator

Номер: US20130281918A1
Автор: Koichi Hayakawa
Принадлежит: Terumo Corp

An applicator insertable into a living body includes a nozzle having an elongated nozzle main body and a nozzle head on a front end side of the nozzle main body and through which liquid together with gas is expelled, with the nozzle main body including a flexible curved section. The applicator also includes an outer tube in which is positioned a portion of the nozzle main body so as to be movable along a longitudinal direction. The angle or degree of curvature of the curved section is changed by inserting the curved section into the outer tube to thereby adjust the direction of the nozzle head relative to the axis of the nozzle main body. In addition, a longitudinally extending gap exists between the outer tube and the nozzle. The gap functions as a discharge path for discharging the gas within the body cavity.

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Номер записи: 59
24-10-2013 дата публикации

TRANSDERMAL THERAPEUTIC SYSTEM (TTS) COMPRISING ROTIGOTINE

Номер: US20130281944A1
Автор: Becker Ulrich, Breitenbach Armin, Drescher Christian, Janssen Christian
Принадлежит: ratiopharm GmbH

The present invention relates to a patch containing the active ingredient rotigotine for the transdermal delivery of the active pharmaceutical agent rotigotine, comprising a backing layer (1), a matrix layer (2) containing the active ingredient, and a removable protective sheet (4) which is intended for removal before the patch is applied to the skin, characterized in that disposed with areal coverage between the matrix layer (2) and the removable protective sheet (4) is an additional interlayer (3). 1. A transversal therapeutic system (TTS) containing an active ingredient rotigotine or a pharmaceutically acceptable salt thereof and having a backing layer (1) which is impermeable to the active ingredient , a matrix layer (2) containing the active ingredient and a removable protective sheet (4) which is intended for removal before the patch is applied to the skin , characterized in that a first interlayer (3) is disposed with areal coverage between the matrix layer (2) and the removable protective sheet (4).2. The TTS according to claim 1 , wherein the first interlayer (3) consists of a pressure-sensitive polymer adhesive.3. The TTS according to claim 1 , wherein the matrix layer (2) consists of non-adhesive polymers having long aliphatic chains and has a second interlayer (5) consisting of the same material as the first interlayer (3).4. The TTS according to claim 1 , wherein the thickness of the interlayer(s) is between 4 μm and 25 μm.5. The TTS according to claim 1 , wherein the active ingredient is rotigotine in the free base form.6. The TTS according to claim 1 , wherein the active ingredient is rotigotine in the form of an ionic liquid claim 1 , wherein the ionic liquid comprises:(a) at least one rotigotine cation and at least one type of counterion obtained from an organic compound; or(b) at least one rotigotine anion and at least one type of counterion obtained from an organic compound.7. The TTS according to claim 6 , wherein the ionic liquid comprises at ...

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Номер записи: 60
31-10-2013 дата публикации

ANTISEPTIC APPLICATOR

Номер: US20130287471A1
Автор: Boone Kyle W., GUZMAN Manuel
Принадлежит:

An applicator assembly includes a container having a proximal end, a distal end, and an interior portion defining a chamber, an application member attached to the distal end of the container, and a tearable solution reservoir disposed within the chamber, the tearable solution reservoir comprising a tearing member, wherein actuating the tearing member to tear the tearable solution reservoir brings the container, the tearable solution reservoir, and the application member into fluid communication with each other. 1. An applicator assembly comprising:a container having a proximal end, a distal end, and an interior portion defining a chamber;an application member attached to the distal end of the container; anda tearable solution reservoir disposed within the chamber, the tearable solution reservoir comprising a tearing member,wherein actuating the tearing member to tear the tearable solution reservoir brings the container, the tearable solution reservoir, and the application member into fluid communication with each other.2. The applicator assembly of claim 1 ,wherein the container further comprises an opening, andwherein the tearing member is accessible via the opening.3. The applicator assembly of claim 1 , wherein the tearable solution reservoir further comprises at least one tear line abutting the tearing member.4. The applicator assembly of claim 1 ,wherein the tearable solution reservoir further comprises a locking mechanism,wherein the container further comprises a projecting element mateable with the locking mechanism, andwherein mating the projecting element with the locking mechanism prevents movement of the tearable solution reservoir within the container.5. The applicator assembly of claim 4 ,wherein the projecting element comprises one or more of a hook and a first knurled surface, andwherein the locking mechanism comprises one or more of an insertion hole and a second knurled surface.6. The applicator assembly of claim 5 ,wherein the hook is mateable with ...

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Номер записи: 61
31-10-2013 дата публикации

Portable container and method of manufacturing the same

Номер: US20130287472A1
Автор: Chin-Chung Cheng
Принадлежит: DAAN BIOTECH CO Ltd

A portable cosmetic container is disclosed. The portable cosmetic container includes a tube that has a receiving space with an opening at one end, and a crease is located at a bottom portion of the receiving space, so that a user can easily break the tube from the crease to form the opening of the receiving space. Substance is partially filled in the receiving space, and air therein is extracted to form a negative pressure status. It is advantageous that when a user breaks the tube from the crease, the substance will not randomly spray out since the air pressure moves towards the opening to keep the substance in the receiving space.

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Номер записи: 62
31-10-2013 дата публикации

SKIN TREATMENT PROCESS AND DEVICE

Номер: US20130289501A1
Автор: Bhattacharya Arpita, Ghosh Dastidar Sudipta, Nethaji Alagirisamy, Shresth Rudra Saurabh, Subrahmaniam Narayanan
Принадлежит:

The present invention is in the field skin treatment, in particular and deep pore cleansing and delivery of benefit agents deep inside the pores. The invention further relates to air-water jet devices for providing said skin treatment. Accordingly it is an object of the invention to provide for a device and process for deep pore skin cleansing, especially, a process for skin cleansing using reduced amounts of water. We have found that a skin cleaning device comprising an air-water jet, wherein the air and water are mixed outside the nozzle(s), provides improved cleansing of skin, including deep poor cleansing, with low usage of water. 1. A process for treating a keratinous substrate with a cleaning device comprising i) a first nozzle is in fluid communication with a feed liquid source; and', 'ii) a second nozzle connected to a source of compressed air characterised in that both nozzles are positioned relative to a central axis, and wherein, 'a) an air-water jet device comprising two nozzles whereinb) the first nozzle is at an angle of between 1 and 60° relative to the central axis; andc) the second nozzle is at an angle of between 1 and 45° relative to the central axis; andwherein the air nozzle does not co-axially surround the water passage and wherein the mouth of the second nozzle is positioned more forward in the direction of the flow along the direction of the central axis than the mouth of the first nozzle, wherein the offset distance between the mouth of the first nozzle and the second nozzle is between 0.5 and 5 mm in said direction.2. A process according to claim 1 , wherein a benefit agent is deposited to skin claim 1 , hair or scalp through the first nozzle.3. A process according to claim 1 , wherein the benefit agent deposited onto the skin and is selected from anti acne actives claim 1 , anti ageing actives claim 1 , skin lightening agents or combinations thereof.4. A process according to claim 1 , wherein the benefit agent deposited onto the hair or ...

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Номер записи: 63
07-11-2013 дата публикации

HYDROGEN SUIT FOR SKIN EXPOSURE

Номер: US20130296768A1
Автор: Heiser Jeremy, Joshi Ashok V.
Принадлежит:

A system facilitates creating a controlled hydrogen rich environment around a patient. The system includes an enclosure, at least one opening, and a hydrogen source. The enclosure forms an internal space to at least partially enclose a body part of the patient. The opening is defined within the enclosure to allow a portion of the body part of the patient to extend out of the internal space of the enclosure. The opening is further configured to form a seal around the body part that extends out of the internal space of the enclosure. The hydrogen source delivers hydrogen gas into the internal space of the enclosure. 1. A system comprising:an enclosure to form an internal space configured to at least partially enclose a body part of a patient;at least one opening defined within the enclosure, wherein the opening is configured to allow a portion of the body part of the patient to extend out of the internal space of the enclosure, wherein the opening is further configured to form a seal around the body part that extends out of the internal space of the enclosure; anda hydrogen source coupled to the enclosure to deliver hydrogen gas into the internal space of the enclosure.2. The system of claim 1 , wherein the enclosure is conformable to the enclosed body part of the patient.3. The system of claim 1 , wherein the at least one opening comprises a collar opening configured to form a seal around the patient's neck.4. The system of claim 3 , further comprising a collar sealing member configured to form a substantial barrier to passage of the hydrogen gas out of the enclosure at the collar opening.5. The system of claim 4 , wherein the collar sealing member comprises:a base region configured to fit through the collar opening and inside of the enclosure;a fold region; anda top region configured to fold, at the fold region, back over a perimeter of the collar opening on an outside portion of the enclosure, wherein pressure from the base region and/or the top region creates the ...

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Номер записи: 64
14-11-2013 дата публикации

BODY PIERCING CLEANSING AND SANITATION DEVICE

Номер: US20130304000A1
Автор: Pentell Christian James
Принадлежит:

A body piercing cleansing and sanitation device is described, which is self-contained and pressurized. The device improves and simplifies the cleaning process, ensuring thorough sanitation through the piercing hole, the external surface of the piercing, and the body ring without needing to remove the body ring. 1. A device for cleansing and sanitizing a pierced body part , comprising:a reservoir for containing cleaning solution, andan enclosable cleansing chamber in fluid communication with the reservoir and adapted to receive and expel the cleaning solution, wherein the cleansing chamber is adapted to envelop the pierced body part and thereby clean the pierced body part when the cleaning solution is received and expelled from the cleansing chamber.2. The device of claim 1 , wherein the cleansing chamber is further adapted to envelop a piercing situated in relation to the pierced body part.3. The device of claim 1 , wherein the cleansing chamber further comprises two dome shaped halves which are closable to envelop the pierced body part.4. The device of claim 3 , wherein the dome shaped halves are hinged at one end and thereby closable to envelop the pierced body part.5. The device of claim 1 , wherein the cleansing chamber further comprises a sealing surface for engagement between the sealing surface and the pierced body part.6. The device of claim 1 , wherein the fluid communication between the reservoir and the enclosable cleansing chamber is pressurized.7. The device of claim 7 , further comprising a pressure pump for pressurizing the fluid communication between the reservoir and the enclosing cleansing chamber. This application claims benefit under 35 U.S.C. §119(e) of U.S. Provisional Patent Application Ser. No. 61/646,457, entitled “BODY PIERCING CLEANSING AND SANITATION DEVICE”, filed May 14, 2012, naming Christian J. Pentell as the inventor, the complete disclosure being incorporated herein by reference.The present application generally relates to a ...

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Номер записи: 65
21-11-2013 дата публикации

APPLICATION OF POLYMERIC MATERIALS TO SCREENS TO FACILITATE HEMOSTASIS AND WOUND HEALING

Номер: US20130310776A1
Автор: Finkielsztein Sergio, Orgill Dennis P., Pietramaggiori Giorgio, Vournakis John N.
Принадлежит:

This invention relates in general to a method and device for facilitating hemostasis and wound healing. In particular, the invention relates to the device comprising a polymeric material disposed on a scaffold that facilitates hemostasis and wound healing. Specifically, the invention contemplates the use of such scaffolds in conjunction with a negative pressure device. 1. A system that delivers sub-atmospheric pressure to the wound for the purpose of wound healing and hemostasis that includes:a) A device that delivers a vacuum pressure in the range of 0 to 250 mm Hg;b) A seal that is semipermeable that covers the wound;c) A tube connecting the appliance to the seal; and (i) A support that promotes uniform distribution of pressure within the wound and', '(ii) A hemostatic agent attached to the support., 'd) a hemostatic appliance comprising2. The system of claim 1 , wherein the hemostatic agent is composed of poly-N-acetylglucosamine with a mean fiber size of about 2 to about 4 microns.3. The system of claim 2 , wherein the support comprises a porous sponge.4. The system of claim 3 , wherein the sponge has a pore size of greater than 10 microns and less than 500 microns.5. The system of claim 4 , wherein the hemostatic agent is comprised of fibers and the fibers have a mean fiber size of less than 10 microns.6. The system of claim 1 , wherein the hemostatic agent is composed of collagen with a mean fiber length of 0.01 to 5 microns in size.7. The system of claim 1 , wherein the hemostatic agent composed of collagen claim 1 , of Type I.8. The system of claim 1 , wherein the hemostatic agent is composed of collagen that has been dispersed in a solution greater than pH 3.2.9. The system of claim 1 , wherein the hemostatic agent is composed of collagen that has a biodegradation time of 0.5 to 10 days.10. The system of claim 1 , wherein the hemostatic agent is composed of collagen that has a thickness on the screen of 0.01 to 100 microns.11. The system of wherein the ...

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Номер записи: 66
21-11-2013 дата публикации

PATCH AND PATCH PREPARATION

Номер: US20130310777A1
Автор: IWAO Yoshihiro, MATSUOKA Kensuke, Nishimura Masato, Okada Katsuhiro
Принадлежит: NITTO DENKO CORPORATION

The invention provides a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bloom even when an organic fluid component having high polarity is contained therein. The patch contains a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 500,000-1,600,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug. 1. A patch comprising a support and an adhesive layer on at least one surface of the support , wherein the adhesive layer comprises a synthetic rubber having a viscosity average molecular weight of 500 ,000-1 ,600 ,000 , an organic fluid component having high polarity , a tackifier , and magnesium aluminometasilicate.2. The patch according to claim 1 , wherein the organic fluid component having high polarity has an angle within the range of 20°-80° as calculated by the following formula using an inorganic value and an organic value in an organic conceptual diagram:{'br': None, 'sup': '−1', 'Angle [°]=arctan (organic value/inorganic value)×(180/π)'}3. The patch according to claim 1 , further comprising an organic fluid component having low polarity which shows lower polarity than the organic fluid component having high polarity.4. The patch according to claim 3 , wherein the organic fluid component having low polarity has an angle within the range of 0°-19° as calculated by the following formula and using an inorganic value and an organic value in an organic conceptual diagram:{'br': None, 'sup': '−1', 'Angle [°]=arctan (organic value/inorganic value)×(180/π)'}5. The patch according to claim 3 , wherein the total content of the organic fluid component having high polarity and the organic fluid component having low polarity in the adhesive ...

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Номер записи: 67
28-11-2013 дата публикации

Transdermal Delivery Systems

Номер: US20130317456A1
Автор: Brown James E., Kwon Sung Yun, Song Xiaoping, Yum Su Il
Принадлежит: DURECT CORPORATION

Disclosed are bupivacaine transdermal delivery systems, and related methods. 125.-. (canceled)26. A system comprising:a backing layer;a reservoir; anda release liner; (i) a high molecular weight polyisobutylene having a viscosity average molecular weight of 450,000 to 2,100,000; and', '(ii) a low molecular weight polyisobutylene having a viscosity average molecular weight of 1,000 to 450,000; and', 'the reservoir further comprising at least one member selected from 1,6-hexanediol lactate glycolate, 1,6-hexanediol lactate caproate, glycerol lactate caproate, glycerol lactate glycolate, glycerol lactate glycolate with succinic anhydride, glycolic acid lactate glycolate, and lactic acid lactate glycolate., 'wherein the reservoir is an adhesive type matrix comprising a blend of27. The system of claim 26 , wherein the ratio of high molecular weight polyisobutylene:low molecular weight polyisobutylene is from 20:80 to 70:30 by weight.28. The system of claim 27 , wherein the ratio of high molecular weight polyisobutylene:low molecular weight polyisobutylene is from 40:60 to 50:50 by weight.29. The system of claim 26 , wherein the high molecular weight polyisobutylene has a viscosity average molecular weight of about 1 claim 26 ,100 claim 26 ,000 and the low molecular weight polyisobutylene has a viscosity average molecular weight of about 50 claim 26 ,000-55 claim 26 ,000.30. The system of claim 26 , wherein the reservoir further comprises a plasticizer.31. The system of claim 30 , wherein the plasticizer is selected from polybutene claim 30 , mineral oil claim 30 , linseed oil claim 30 , octyl palmitate claim 30 , squalene claim 30 , silicone oil claim 30 , isobutyl stearate claim 30 , olive oil claim 30 , isopropyl myristate claim 30 , isostearyl alcohol and oleyl alcohol.32. The system of claim 31 , wherein said plasticizer comprises polybutene.3326. The system of claim. claim 31 , wherein the backing layer comprises a breathable material comprising woven or non-woven ...

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Номер записи: 68
28-11-2013 дата публикации

Transdermal delivery system for hormones and steroids

Номер: US20130317462A1
Автор: Adam Watkinson, Kerrie Setiawan
Принадлежит: Acrux DDS Pty Ltd

A transdermal delivery system comprising a composition comprising a pharmacological agent and a penetration enhancer wherein the penetration enhancer comprises polyethylene glycol (PEG) of average molecular weight no more than 300.

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Номер записи: 69
05-12-2013 дата публикации

COTTON BALLS, COTTON SWABS AND COTTON SWAB HOLDER

Номер: US20130324948A1
Автор: Baschnagel Robert J.
Принадлежит:

A cotton swab and cotton swab holder, which can be used together in a cotton swab holder assembly. The cotton swab having a shaft and a cotton portion disposed on an end of the shaft. The cotton swab holder having a handle portion; and a cotton swab holding portion connected to the handle portion, the cotton swab holding portion having a mechanism for holding the shaft of the cotton swab. Also provided is a cotton ball including: a cotton body; a wall defining a cavity disposed on an interior of the cotton body; and one of a liquid or gel contained in the cavity. 1. A cotton ball comprising:a cotton body;one or more walls defining a cavity disposed on an interior of the cotton body; andone of a liquid or gel contained in the cavity.2. The cotton ball of claim 1 , wherein the one or more walls comprise a thin film encapsulating the liquid or gel which can be burst upon application of pressure to the cotton body claim 1 , thereby dispensing the liquid or gel from the cavity and into the cotton body.3. The cotton ball of claim 1 , further comprising a piercing member disposed on the cotton body claim 1 , the piercing member having a body and at least one projection wherein the body is pressed to force the projection to pierce the one or more walls claim 1 , thereby dispensing the liquid or gel from the cavity and into the cotton body.4. The cotton ball of claim 1 , further comprising a biasing means for biasing the projection away from the one or more walls.5. The cotton ball of claim 1 , wherein the liquid or gel is a medicament.6. The cotton ball of claim 1 , wherein the liquid or gel is a solvent.7. The cotton ball of claim 1 , wherein the liquid or gel is a cleaner. This application is a Divisional Application of U.S. Ser. No. 12/647,051 filed on Dec. 24, 2009. The entire contents of which are herein incorporated by reference.1. FieldThe present invention relates generally to cotton products and, more particularly, to cotton balls, cotton swabs and cotton swab ...

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Номер записи: 70
12-12-2013 дата публикации

FLUID APPLICATION DEVICE AND METHOD

Номер: US20130330114A1
Автор: Benokraitis Kristin L., Casey Ronald J., Foshee David L., Hathaway Royal D., Jardine Nicholad J., Mosler Theodore J., Vanek Patrick P.
Принадлежит: Otsuka America Pharmaceutical, Inc.

The present invention provides a device, a system, and a method for application of fluids. 128-. (canceled)29. A system for applying a fluid , comprising: first and second opposing packet sides defining therebetween a sealed space containing the fluid;', 'a frangible area configured to rupture upon compressing the packet to release the fluid from the packet; and', 'a collapsibility feature enabling the first packet side of the packet to invert from a convex position to a concave position upon compressing the packet so that the formerly sealed space is substantially completely collapsed; and, 'a packet containing a fluid, the packet comprising a handle having a proximal end and a distal end, the handle comprising a receptacle at the proximal end of the handle, the receptacle configured to receive the packet of the fluid and facilitate expulsion of the fluid from the packet;', 'a base disposed at the distal end of the handle and configured to direct flow of the released fluid and including a distal opening; and', 'an applicator pad configured to be coupled to the base, in fluid communication with an interior portion of the receptacle via the distal opening of the base., 'an applicator device comprising30. The system of claim 29 , wherein the receptacle has a substantially round shape.31. The system of claim 30 , wherein a central receptacle axis through the substantially round shape of the receptacle is oriented at an angle relative to an axis perpendicular to a plane including the base.32. The system of claim 31 , wherein the angle is approximately 90 degrees.33. The system of claim 31 , wherein the packet has a substantially round shape that is configured to fit concentrically within the substantially round shape of the receptacle.34. The system of claim 33 , wherein the receptacle and the packet have corresponding orienting features that orient the packet with respect to the receptacle.35. The system of claim 34 , wherein the orienting features comprise a structure ...

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Номер записи: 71
12-12-2013 дата публикации

COMPOSITIONS AND METHODS FOR TOPICAL NITRIC OXIDE GENERATION

Номер: US20130330244A1
Автор: Balaban Alexandru T., Seitz WIlliam A., Smith Kenneth A.
Принадлежит: NIOXX LLC

A simple, biocompatible two-component system and procedure for generating nitric oxide (NO) is described. One component comprises sodium nitrite or other nitrite source, and the other component comprises a reductant, an acid and a base although in certain embodiments the reductant and acid functions are provided by the same component. When these two components are mixed directly at a local site of administration or immediately prior to application and the mixture generates nitric oxide (NO) for topical application. The activated system is therapeutic for treatment of multiple conditions, including promotion of healing, disinfection, promotion of hair growth, and treatment of male and female sexual dysfunction. 1. A biocompatible two-component nitric oxide (NO) delivery system that comprises:a nitric oxide donor composition comprising a nitrite salt in a first gel, anda nitric oxide activation composition comprising at least one reductant, at least one organic acid and at least one conjugate base of the organic acid mixed together in a second gel, wherein the pH of the activation composition is greater than 3.0,wherein the nitric oxide donor composition and nitric oxide activation composition are stable when stored separately and generate a source of nitric oxide when admixed, the admixture characterized by an initial pH greater than 4.0.2. The system of claim 1 , wherein the nitrite salt is selected from one or more of the group consisting of: sodium nitrite claim 1 , potassium nitrite claim 1 , and calcium nitrite.3. The system of claim 1 , wherein the organic acid is selected from one or more of the group consisting of: citric acid claim 1 , ascorbic acid claim 1 , lactic acid claim 1 , glyceric acid claim 1 , and formic acid.4. The system of claim 1 , wherein the organic acid is ascorbic acid and the ascorbic acid further functions as the at least one reductant.5. The system of claim 1 , wherein the organic acid is an ascorbic acid derivative and the ascorbic ...

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Номер записи: 72
12-12-2013 дата публикации

GAS-ASSISTED DEVICE AND METHOD FOR DISPENSING BIOMATERIALS

Номер: US20130331771A1
Автор: Hoogenakker Jon E., Kirk Thomas Allan, Robb Bradley D., Sharratt Todd William
Принадлежит: Nordson Corporation

A gas-assisted fluid-dispensing device configured to deliver an aerosol onto a surgical site. The fluid-dispensing device includes at least one fluid chamber configured to contain a fluid. The fluid chamber has a distal end and proximal end. A plunger extends at least partially into the fluid chamber from the proximal end. A spray nozzle tip is fluidly coupled to the distal end of the fluid chamber and is coupled to a gas supply. The tip is capable of generating aerosol with a gas from the gas supply and the fluid from the fluid chamber. A housing has an upper portion with a docking port configured to operably receive the fluid chamber. An actuating member is operably coupled to a plunger and is configured to apply a force to the plunger to discharge fluid from the fluid chamber and into the tip. 1. A gas-assisted fluid-dispensing device configured to deliver an aerosol onto a surgical site , the fluid-dispensing device comprising:first and second fluid chambers configured to contain first and second fluids respectively, the first and second fluid chambers each including a distal end and a proximal end;first and second plungers extending respectively at least partially into the first and second fluid chambers from the proximal ends thereof;a spray nozzle tip fluidly coupled to the distal ends of the first and second fluid chambers and configured to have a gas supply coupled thereto, the spray nozzle tip capable of generating the aerosol with a gas from the gas supply and the fluids from the first and second fluid chambers;a housing having a handle and an upper portion having a docking port configured to operably receive the first and second fluid chambers; andan actuating member operably coupled to the first and second plungers and configured to apply a force to the first and second plungers to discharge the fluids from the first and second fluid chambers and into the spray nozzle tip.2. The gas-assisted fluid-dispensing device of claim 1 , wherein the actuating ...

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Номер записи: 73
19-12-2013 дата публикации

DISPENSING APPLICATOR FOR FLUIDS

Номер: US20130336705A1
Автор: Brown James, Kaufman Jack W.
Принадлежит: BlOMED PACKAGING SYSTEMS INC.

A hand-held dispensing applicator comprising a fluid source, a frangible applicator tip attached to the fluid source, and an absorbent member attached to the frangible applicator tip is provided. When the frangible applicator tip is broken, fluid flows from the source to the absorbent member, whereby the fluid is applied and spread on a surface. Preferably, the frangible applicator tip comprises a support element permanently connected to the fluid source, a relatively rigid tongue element extending outwardly of the support element, and a frangible region there between. Preferably, the tongue element comprises ribs for reinforcing the tongue element to resist unintentional breaking of the frangible region. More preferably, the applicator tip comprises a semi-permeable or non-permeable cover disposed around the frangible region to control the speed and direction of the dispersion of the fluid in the absorbent member. 120.-. (canceled)21. A liquid dispensing applicator , said applicator comprising:(a) a hand-held liquid source for housing a liquid, said source comprising a body having a distal end and a proximal end; and (i) an attachment portion for insertion into said proximal end of said body to secure said liquid dispenser to said body, said attachment portion having a passage therethrough to allow said liquid to flow from said body through said liquid dispenser;', '(ii) an attachment member connected to said attachment portion to maintain said attachment portion seated within said proximal end, said attachment member having a passage therethrough to allow fluid to flow from said attachment portion through said liquid dispenser;', '(iii) at least one capillary tube configured to provide fluid communication between said liquid source and said liquid dispenser upon application of pressure to said liquid source; and', '(iv) a tongue element extending outwardly from said attachment portion, said tongue element capping said attachment portion., '(b) a liquid dispenser ...

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Номер записи: 74
19-12-2013 дата публикации

Percutaneous application system

Номер: US20130338610A1
Автор: Alexander Teslenko, Dieter Gulik, Friedrich Von Hahn
Принадлежит: Meddrop Tech AG

The invention relates to an application system for the transepidermal surface administration of medications, said system comprising a container ( 1 ) accommodating a sprayable, active agent-containing composition, a propellant gas source ( 3 ) for pressurized gas consisting of at least 25% v/v of oxygen, and a spraying device ( 2 ), wherein container ( 1 ), propellant gas source ( 3 ), and spraying device ( 2 ) are flow-connected with each other in such a manner that the propellant gas atomizes the sprayable composition and, when the spraying device ( 2 ) is actuated, forces it out of the spraying device ( 2 ), with the composition being forced out of the spraying device ( 2 ) in the form of a conical spray jet at an exit velocity of ≧100 m/s. With the help of the inventive application system active agents can be effectively administered via the skin without causing injury to the skin. As a result of the high exit velocity the penetration rate is especially favorable even when larger molecules are introduced.

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Номер записи: 75
19-12-2013 дата публикации

TRANSDERMAL DRUG DELIVERY METHOD AND SYSTEM

Номер: US20130338645A1
Автор: DiPierro Guy, Imanidis Georgious, Zumbrunn Werner
Принадлежит:

The invention concerns a transdermal delivery system for controlled dispensing of an active substance to and through a porous surface. A certain amount of fluid comprising at least one active substance and at least one solvent is dispensed into an administration reservoir. In the administration reservoir the at least one solvent is separated from the administration reservoir by a solvent recovery means such that the active substance achieves a certain level on an interface device which is permeable for the one active substance. Thereby the active substance is absorbable via diffusion from the interface device by a porous surface to be treated. 134.-. (canceled)35. A method for transdermal administration of at least one active substance to a porous surface comprising:(a) storing at least one active substance in at least one substance reservoir;(b) storing at least one solvent, operable to solubilize or disperse the at least one active substance, in at least one solvent reservoir;(c) dispensing a first portion of the at least one active substance from the at least one substance reservoir and dispensing a second portion of the at least one solvent from the at least one solvent reservoir to at least one administration reservoir forming a solution or dispersion of the at least one active substance;(d) transferring the solution or dispersion of the at least one active substance from the at least one administration reservoir to at least one interface, wherein the interface is interposed between the administration reservoir and the porous surface;(e) removing the at least one solvent from the at least one administration reservoir by at least one solvent removal element; and(f) delivering the solution or dispersion of the at least one active substance from the at least one interface to the porous surface.36. The method of claim 35 , wherein the at least one substance reservoir and the at least one solvent reservoir exist as a common reservoir.37. The method of claim 35 , ...

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Номер записи: 76
19-12-2013 дата публикации

Biodegradable, Active Ingredient-Eluting Structural Support

Номер: US20130338700A1
Автор: MATHENY Keith E.
Принадлежит: Matheny Enterprises, LLC

A biodegradable nasal splint, wherein the biodegradable nasal splint is configured for placement within a nasal passage so as to stabilize a surgically-corrected septum. A biodegradable nasal splint, wherein the biodegradable nasal splint is configured for placement within a nasal passage so as to exert a lateralizing force to an outfractured inferior turbinate. A method comprising performing a corrective procedure with respect to a patient's nasal passage, positioning a biodegradable nasal splint within the patient's nasal passage, wherein the biodegradable nasal splint is effective to exert a lateralizing force to an inferior turbinate, to stabilize a nasal septum, or combinations thereof. 1. A biodegradable nasal splint , wherein the biodegradable nasal splint is configured for placement within a nasal passage so as to stabilize a surgically-corrected septum.2. The biodegradable nasal splint of claim 1 , wherein the biodegradable splint is configured to exert a radially outward force.3. The biodegradable nasal splint of claim 1 , wherein the biodegradable splint comprises at least 90% by weight of one or more degradable materials.4. The biodegradable nasal splint of claim 4 , wherein the degradable material is configured such that at least 95% by weight of the degradable material will degrade in a duration of from about 7 days to about 30 days upon deployment within a nasal passage.5. The biodegradable nasal splint of claim 1 , further comprising an active ingredient comprising a corticosteroid claim 1 , an antihistamine claim 1 , an anticholinergic agent claim 1 , an antibiotic claim 1 , or combinations thereof.6. The biodegradable nasal splint of claim 5 ,wherein the corticosteroid comprises beclomethasone, budesonide, ciclesonide, fluticasone furoate, fluticasone propionate, flunisolide, mometasone, triamcinolone, or combinations thereof,wherein the antihistamine comprises azelastine, olopatadine, or combinations thereof,wherein the anticholinergic agent ...

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Номер записи: 77
26-12-2013 дата публикации

Insect Bite Itch Stopper

Номер: US20130345648A1
Автор: Daffemer Garret Kane, Hinden Joseph Gavigan, Huster Benjamin Ward
Принадлежит:

An insect-bite itch stopper is disclosed which has a pressure surface adapted for pressing directly onto an insect bite and an applicator for simultaneously or contemporaneously applying an anti-itch medication to the bite. 1. A device comprising:a pressure surface capable of creating uneven pressure within an insect bite;an applicator capable of applying an effective amount of anti itch formulation to the insect bite, where the applicator and the pressure surface are oriented about each other such that the pressure surface and the applicator contact the insect bite contemporaneously.2. A device comprising:a pressure surface capable of creating uneven pressure within an insect bite;an applicator capable of applying an effective amount of anti itch formulation to the insect bite, where the applicator and the pressure surface form a compound surface capable of contemporaneously applying the pressure surface and the applicator to the insect bite.3. The device of further comprising:a pressure surface further comprising a plurality of intersecting blades adapted to be pressed against the surface of an insect bite and create unbalanced pressures within the bite.4. The device of further comprising:a housing with a front end and a back end; 'a permeable barrier on the front end of the liquid storage reservoir;', 'a liquid storage reservoir with a front end and a back end within the housing, the liquid storage reservoir further comprising 'cut outs that define an empty space, and;', 'an applicator tip, shaped to fit snugly within the housing, and extending past the front end of the housing, in communication with the permeable barrier, further comprisinga pressure surface adapted to fit within the empty space formed by the cut-outs.5. The device of further comprising: a spring stop on the inside surface of the housing;', 'a cut-out that defines a hole in the back end of the housing;, 'a housing with a front end, a back end, and an inside surface, the housing further ...

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Номер записи: 78
02-01-2014 дата публикации

External Preparation Kit

Номер: US20140005615A1
Автор: Kishimoto Satoko, Takashimizu Chisato, YAGYU Kazuhiro, Yasugi Daisuke
Принадлежит: SHISEIDO COMPANY, LTD.

An external preparation kit is provided, which has a gel sheet having excellent water-releasing property and elongation, and a water-soluble sheet having excellent solubility. Thus, an external preparation kit according to the invention comprises: 1. An external preparation kit comprising: (a) 1-6% by mass of a composition comprising 10-80% by mass of carrageenan, 5-50% by mass of locust bean gum, 5-50% by mass of xanthan gum, and 5-50% by mass of mannan; and', '(b) water; and, '(I) a gel sheet containing(II) a water-soluble sheet containing one or more component(s) selected from the group consisting of a cellulose derivative, polyvinyl alcohol, collagen, starch, gelatin, agar, and sugar.2. The external preparation kit according to wherein the composition (a) contains carrageenan at 25-35% by mass claim 1 , locust bean gum at 20-30% by mass claim 1 , xanthan gum at 20-30% by mass claim 1 , and mannan at 15-25% by mass.3. The external preparation kit according to wherein a blending amount of the composition (a) is 1-2.5% by mass.4. The external preparation kit according to wherein claim 1 , in the composition claim 1 , a weight ratio between locust bean gum and xanthan gum is from 2:1 to 1:2.5. The external preparation kit according to claim 1 , wherein the (II) water-soluble sheet contains hydroxypropyl methylcellulose.6. The external preparation kit according to claim 1 , wherein an area of a surface on a side contacting the (II) water-soluble sheet of the gel sheet (I) is larger than an area of a surface on a side contacting the gel sheet of the water-soluble sheet.7. A method of using the external preparation kit according to claim 1 , comprising:laying a gel sheet (I) on a water-soluble sheet (II) so that the gel sheet (I) covers a whole surface on one side of the water-soluble sheet (II) completely.8. The external preparation kit according to claim 2 , wherein a blending amount of the composition (a) is 1-2.5% by mass.9. The external preparation kit according ...

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Номер записи: 79
02-01-2014 дата публикации

FENTANYL TRANSDERMAL PATCH

Номер: US20140005617A1
Автор: Choi Young Kwen, Kim Jung Ju, KIM Sung Soo, Lee Jung Sik
Принадлежит:

Provided is a fentanyl transdermal patch comprising an acrylic-rubber hybrid as a drug-adhesive layer. The fentanyl transdermal patch can maintain constant fentanyl skin permeability for three days by maintaining close contact with the skin such that desorption, release by moisture and sweat, and skin stimulation are all improved. 1. A fentanyl transdermal patch comprising:a backing layer and a drug-adhesive layer at one side of the backing layer,wherein the drug-adhesive layer comprises 90 parts by weight to 60 parts by weight of an acrylic-rubber hybrid polymer, and 5 parts by weight to 20 parts by weight of at least one drug selected from fentanyl, fentanyl derivatives and pharmaceutical salts thereof.2. The fentanyl transdermal patch according to claim 1 , wherein the fentanyl derivative is alfentanyl claim 1 , carfentanyl claim 1 , lofentanyl claim 1 , remifentanyl claim 1 , sufentanil claim 1 , or trefentanyl.3. The fentanyl transdermal patch according to claim 1 , wherein the drug-adhesive layer has a thickness ranging from 20 μm to 200 μm.4. The fentanyl transdermal patch according to claim 1 , wherein the acrylic-rubber hybrid polymer is formed by grafting a rubber type polymer of polyethylene-butylene claim 1 , polyethylene-vinyl acetate claim 1 , polybutylene claim 1 , polystyrene-isoprene claim 1 , or polystyrene-isoprene-butadiene to an acrylic polymer consisting of 2-ethylhexyl acrylate claim 1 , butyl acrylate claim 1 , isooctyl acrylate claim 1 , methyl acrylate claim 1 , methyl methacrylate claim 1 , acrylic acid claim 1 , 2-hydroxyethyl acrylate claim 1 , or vinyl acetate.5. The fentanyl transdermal patch according to claim 1 , further comprising: 5 parts by weight to 20 parts by weight of at least one transdermal absorption enhancer selected from the group consisting of N-methyl-2-pyrrolidone claim 1 , N-caprylic-2-pyrrolidone claim 1 , N-dodecyl-2-pyrrolidone claim 1 , glycerol lauryl alcohol claim 1 , oleyl alcohol claim 1 , isopropyl myristate ...

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Номер записи: 80
09-01-2014 дата публикации

Wearable patch comprising multiple separable adhesive layers

Номер: US20140012102A1
Автор: Mark Travaglini, Ranjit Das
Принадлежит: ZANSORS LLC

Wearable patches comprising multiple separable adhesive layers. One or more of the layers can comprise electronics, mechanical components, gauze, medicine and/or other types of hardware suitable for the intended use of the patch. In use, a first layer of the patch is adhered to a user. When it is time to change layers, the patch is removed from the user, the first layer is removed from the patch to expose a second adhesive layer, and the second layer is applied to the user. The process may be repeated until the remaining layers of the patch have been used.

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Номер записи: 81
16-01-2014 дата публикации

METHOD AND DEVICE OR PHARMACEUTICAL COMPOSITIONS FOR THE TRANSDERMAL DELIVERY OF MAGNESIUM DIRECTLY TO THE NEUROMUSCULAR JUNCTION FOR THE TREATMENT OF MUSCLE CRAMPING

Номер: US20140018750A1
Автор: Pagliaro Marie M., Pagliaro Michael J.
Принадлежит:

A method for treating muscle cramping (e.g., acute nocturnal) includes the steps of placing a transdermal delivery agent on skin above an affected muscle that is in spasm. The transdermal delivery agent includes a composition that includes a therapeutic amount of magnesium. Placement of the transdermal delivery agent on the skin results in transdermal delivery of the magnesium directly to the affected muscle that is in spasm, thereby providing therapeutic relief while limiting the delivery of the magnesium to the entire circulatory system (systemic effect). 1. A method for treating muscle cramping comprising the step of:placing a transdermal delivery agent on skin above an affected muscle that is in spasm, wherein the transdermal delivery agent includes a composition that includes a therapeutic amount of magnesium, wherein placement of the transdermal delivery agent on the skin results in transdermal delivery of the magnesium directly to the affected muscle that is in spasm, thereby providing therapeutic relief.2. The method of claim 1 , wherein the transdermal delivery agent comprises a transdermal patch that includes a reservoir that contains the composition and a membrane covering the reservoir and constructed such that the magnesium passes therethrough.35. The method of claim 1 , wherein the therapeutic amount of magnesium is selected such that therapeutic relief is observed within about minutes from placing the transdermal delivery agent on the skin.4. The method of claim 1 , wherein the magnesium in the magnesium containing composition comprises magnesium sulfate.5. The method of claim 4 , wherein magnesium sulfate is present in an amount of about 8% by weight (MW) of the total magnesium containing composition.6. The method of claim 1 , wherein the magnesium containing composition is selected from the group consisting of an aqueous transdermal gel claim 1 , an aqueous transdermal lotion claim 1 , an aqueous transdermal ointment claim 1 , and an aqueous ...

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Номер записи: 82
16-01-2014 дата публикации

METHODS AND DEVICES FOR ACTIVATING BROWN ADIPOSE TISSUE WITH TARGETED SUBSTANCE DELIVERY

Номер: US20140018767A1
Автор: Aronhalt Taylor W., Harris Jason L., Henninger Dwight, Kaplan Lee M., Stylopoulos Nicholas, Voegele James W.
Принадлежит:

Methods and devices are provided for activating brown adipose tissue with targeted substance delivery. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a chemical configured to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly can be delivered to a patient, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The chemical can be delivered to the patient locally and/or systemically to stimulate the nerves and/or the brown adipocytes. 1. A medical method , comprising:positioning a device in contact with tissue of a patient proximate to a receptor in communication with at least a portion of a depot of brown adipose tissue; andactivating the device to deliver a chemical to the patient to activate the brown adipose tissue and increase energy expenditure of the brown adipose tissue.2. The method of claim 1 , wherein the chemical is configured to chemically interact with cellular surface receptors of the brown adipose tissue.3. The method of claim 1 , wherein the chemical comprises one of a depolarization agent claim 1 , a hormone-related chemical claim 1 , an odiferous agent claim 1 , a Melanocortin receptor 4 (MCR4) protein agonist claim 1 , a TRPA1 agonist claim 1 , and a TRPV1 agonist.4. The method of claim 1 , further comprising delivering a second chemical to the patient claim 1 , the chemical being configured to respond to the second chemical when the chemical is exposed to the second chemical claim 1 , the response of the chemical causing activation of the brown adipose tissue.5. The method of claim 1 , further comprising targeting the chemical to a nerve innervating the brown adipose tissue to activate the brown adipose tissue.6. The method of claim 1 , wherein the depot of brown ...

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Номер записи: 83
30-01-2014 дата публикации

SILICONE ADHESIVE COMPOSITIONS

Номер: US20140031734A1
Автор: Joshi Pranav Ramchandra, Saxena Anubhav
Принадлежит: Momentive Performance Materials Inc.

A silicone adhesive composition including an ionic silicone and useful for healthcare applications such as wound care and drug delivery. 1. A silicone adhesive composition comprising an ionic silicone wherein the ionic silicone is a functionalized ionic silicone having the formula:{'br': None, 'sup': 1', '2', '3', '1', '2', '3', '1', '2', '3, 'sub': a', 'b', 'c', 'd', 'e', 'f', 'g', 'h', 'i', 'j, 'MMMDDDTTTQ\u2003\u2003(I)'}wherein:{'sup': 1', '1', '2', '3, 'sub': '1/2', 'M=RRRSiO'}{'sup': 2', '4', '5', '6, 'sub': '1/2', 'M=RRRSiO'}{'sup': 3', '7', '8', '9, 'sub': '1/2', 'M=RRRSiO'}{'sup': 1', '10', '11, 'sub': '2/2', 'D=RRSiO'}{'sup': 2', '12', '13, 'sub': '2/2', 'D=RRSiO'}{'sup': 3', '14', '15, 'sub': '2/2', 'D=RRSiO'}{'sup': 1', '16, 'sub': '3/2', 'T=RSiO'}{'sup': 2', '17, 'sub': '3/2', 'T=RSiO'}{'sup': 3', '18, 'sub': '3/2', 'T=RSiO'}{'sub': '4/2', 'Q=SiO'}{'sup': 1', '2', '3', '5', '6', '8', '9', '10', '11', '12', '13', '15', '16, 'where R, R, R, R, R, R, R, R, R, R, R, Rand Rare aliphatic, aromatic or fluoro containing monovalent hydrocarbon radicals containing from 1 to about 60 carbon atoms,'}{'sup': 4', '12', '17, 'claim-text': {'br': None, 'sup': x−', 'y+, 'sub': 'n', '-A-IM\u2003\u2003(II)'}, 'where R, Rand Rare monovalent radical bearing ion-pairs having the formula (II)where A is a spacing group having at least one spacing atom selected from a divalent hydrocarbon or hydrocarbonoxy group,{'sub': 3', '3', '3', '3, 'sup': −', '−', '−', '2−', '2−, 'where I is an ionic group selected from sulfonate —SO, sulfate —OSO′, carboxylate —COO, phosphonate —PO and phosphate —OPO,'} {'br': None, 'sub': '2', 'sup': '+', '—R′—NR″—R′″—I\u2003\u2003(III)'}, 'where M is hydrogen or a cation independently selected from alkali metals, alkali earth metals, transition metals, metal complexes, quaternary ammonium and phosphonium groups, organic cations, alkyl cations, cationic hydrocarbons and cationic polymers; or, zwitterions having the formula (III)where R′ is a divalent ...

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Номер записи: 84
30-01-2014 дата публикации

LIQUID DISPENSING CONTAINER

Номер: US20140031768A1
Автор: TAKAKI Shunsuke
Принадлежит:

Disclosed is a container capable of dispensing a liquid contained in the container by drops while keeping the liquid in an uncontaminated state. Also disclosed is a method of dispensing a liquid by drops using the container, and a method of removing a stoma pouch flange using the container. The liquid storing container comprises a storage portion with a sealed periphery and a nozzle portion connected with the storage portion for dispensing a liquid contained in the storage portion by drops to the outside. The container has an enclosed inner space. Liquid is dispensed by drops by peeling apart a sealed nozzle tip portion that is oriented toward the tip of the nozzle portion to form a drop dispensing opening. 18-. (canceled)9. A liquid storing container comprising:a storage portion formed from a single body front and back of a flexible material sealed around a periphery thereof and forming an enclosed inner space;a nozzle portion communicating with the storage portion and acting as a liquid channel for dispensing a liquid stored within the storage portion to outside the container;a nozzle tip portion formed by sealing the nozzle portion toward a tip thereof;a tab portion connected to the nozzle tip portion and constituted by a front surface tab portion and a rear surface tab portion wherein the front and rear surfaces of the flexible material are not sealed;a shoulder portion disposed in a direction of the nozzle tip portion opposite to that of the tab portion, and a body portion connected to the shoulder portion; wherein an angle formed by a line extending left and right from a base portion of the nozzle tip portion formed at a boundary between the nozzle tip portion and the shoulder portion in parallel with a lower edge and a ridge line of an upper portion of a seal portion enclosing the storage portion is from 5 to 60 degrees.10. The liquid storing container according to claim 9 , wherein the nozzle tip portion is formed with an easily peelable seal claim 9 , and a ...

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Номер записи: 85
06-02-2014 дата публикации

Dr. Courtney Henderson's Cure for HIV of the Soul

Номер: US20140039420A1
Автор: Courtney Lynette Henderson
Принадлежит: Individual

A Life-Saving Innovation which utilizes Mind controls/Voice activated Satellite Technology to cure HIV disease of the Soul. Body Scans before and after the process demonstrated that Souls/Agents were cured of HIV The Souls should be a Visible Image. The Satellite—Transforms the Soul into an Invisible Image; performs a series of three Aromatizations; mobilizes materials such as water and a specialized washing solution for the procedure; rinses the Soul with water for two minutes; washes the Soul for three minutes; rinses the Soul for three minutes; performs a series of three Materializations; transforms the Soul into a Visible Image; drys the Soul with heated air at a low velocity for further disinfection. The invention is ten minutes in duration and is usually curative in two treatments; once per consecutive day. Can be performed anywhere in the world. This invention is a “Must-Have.”

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Номер записи: 86
06-02-2014 дата публикации

Method for Treating Poison Ivy and Similar Poison Plant Induced Rashes

Номер: US20140039421A1
Автор: Decker Kate Delano-Condax
Принадлежит:

A method for treating poison ivy and similar poison plant induced rashes utilizes a sealed pouch containing a mixture of anti-inflammatory, analgesic, and anti-oxidant property ingredients. The pouch is placed in a container filled with boiling water. The ingredients in the pouch permeate through the water. A metal applicator has a spoon-shaped section with a curved lower surface and a handle. The spoon-shaped section is inserted into the boiled herbal water mixture. The bottom surface of the curved lower surface of the spoon-shaped section is then momentarily placed on the pustule or red bump of the poison ivy. The applicator is then lifted up away from the area. Usually two or three touches with the applicator on the effected area will completely remove the itching and the itching and pustule will be entirely eliminated within twenty-four to forty-eight hours. 1. A method of treating pustules and other affected areas on the skin caused by poison ivy and similar poison plants comprising the steps of:providing a sealed pouch containing a mixture of ingredients having anti-inflammation, analgesic, and anti-oxidant properties;providing a heat-resistant container;pouring boiling water into the container;placing the pouch within the container;allowing the pouch to soak in the boiling water, thus creating herbally affected water within the container;providing an applicator with a spoon-shaped section having a curved lower surface with a bottom surface and a. handle extending from the spoon-shaped section;inserting the spoon-shaped section into the herbal water in the container;withdrawing the spoon-shaped section from the herbal water;touching only the pustule and not the skin with the bottom surface of the spoon-shaped section of the applicator;lifting the applicator off and away from the pustule after touching it with the spoon-shaped section; andrepeating the steps of inserting the spoon-shaped section into the herbal water, withdrawing the spoon-shaped section from ...

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Номер записи: 87
06-02-2014 дата публикации

FULL-BODY GARMENT OR SYSTEM OF GARMENTS FOR TREATMENT OF SKIN DISORDERS

Номер: US20140039422A1
Автор: Scott Elizabeth Ann
Принадлежит: AD RESCUEWEAR, LLC

Aspects of the present disclosure disclose a garment for treatment of atopic dermatitis. In one aspect, the disclosure is directed a close fitting full body garment. In particular, the full body garment includes a torso covering portion, a pair of leg covering portions and a pair of arm covering portions. The pair of arm covering portions further include an integrated hand covering portions, and the pair of leg covering portions further include a pair of foot covering portions. The disclosed system is constructed from a fabric capable of moisture management that when in contact with the skin surface of the wearer provides an optimal relief from the symptoms of the skin disorder. 1. A garment for treatment of atopic dermatitis comprising:a torso covering portion supporting a pair of leg covering portions and a pair of arm covering portions, wherein the torso covering portion includes a longitudinal elongate opening along the torso covering portion, the longitudinal elongate opening extending through substantially an entire length of the torso covering portion between a neckline of the garment and terminating at around a crotch area, and wherein the torso covering portion, the leg covering portions and the arm covering portions are made from a fabric capable of conforming to a body of a wearer such that the garment remains in substantially direct contact with the skin surface of the wearer, the fabric capable of moisturizing the skin surface and being optimized for moisture absorption when the fabric is being wetted and for a prolonged moisture release when the fabric is placed against the surface of the skin.2. The garment of claim 1 , wherein the junction areas between the torso covering portion the leg covering portions and the arm covering portions of the garment are minimized by forming some of the torso covering portion claim 1 , the leg covering portions and the arm covering portions from a single piece of fabric in order to prevent any unnecessary skin ...

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Номер записи: 88
13-02-2014 дата публикации

METHOD FOR TREATING NON-ACNEIC OILY SKIN

Номер: US20140046241A1
Автор: Granger Corinne, Pernot Helene
Принадлежит: L'OREAL

The present invention relates to a method for cosmetic treatment of non-acneic oily skin, comprising the step consisting in: exposing said non-acneic oily skin to a first quasi-monochromatic light of artificial origin having a dominant wavelength peak between 300 and 700 nm, better still between 400 and 650 nm, even better still between 560 and 620 nm. 1. A method for cosmetically treating non-acneic oily skin , the method comprising:exposing the non-acneic oily skin of a subject in need thereof to a first quasi-monochromatic light of artificial origin having a dominant wavelength peak between 300 and 700 nm.2P. AcnesP. Acnes. The method of claim 1 , wherein a production of sebum is reduced by 8% at least and a population of is reduced by at least 7% by a modification of the modifying at least one nutritional condition for growth.3. The method of claim 2 , further comprising:exposing the non-acneic oily skin of a subject in need thereof, to a second quasi-monochromatic light of artificial origin having a dominant wavelength peak between 700 and 1000 nm.4. The method of claim 1 , wherein the first quasi-monochromatic light is pulsed with a pulse having a duration of between 100 and 500 ms.5. The method of claim 1 , wherein the first quasi-monochromatic light is pulsed with an interpulse interval having a duration of between 50 and 200 ms.6. The method of claim 1 , wherein the first quasi-monochromatic light received by the non-acneic oily skin has a surface power density of less than or equal to 40 mW/cm.7. The method of claim 1 , wherein the non-acneic oily skin is exposed to the first quasi-monochromatic light for a duration of less than 20 minutes.8. The method of claim 1 , wherein the cosmetically treating is carried out at least once a day and at least one day per week.9. The method of claim 1 , wherein the cosmetically treating is carried out at least once a week and for a duration of between two and twelve weeks.10. The method of claim 1 , the method further ...

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Номер записи: 89
13-02-2014 дата публикации

ANTIBIOTIC DELIVERY SYSTEM AND METHOD

Номер: US20140046273A1
Автор: Kang Matthew M.
Принадлежит:

The invention provides a system and method for delivering antibiotic powder to a surgical wound that reduces the likelihood of contamination. A pre-packaged, sterile antibiotic powder delivery system comprises a container; a measured dosage of an antibiotic powder disposed within the container; and a sieve top attached to the top of the container, wherein the container and sieve top are sealed as a unit in a sterile packaging. To use the delivery system in the sterile surgery or operating room environment, the delivery system is removed from the sterile packaging. The delivery system is shaken over the surgical wound for a reasonable amount of time to cover the entire wound, avoid surgeon fatigue at the end of surgery, and avoid prolonging the total time the wound is open. 1. A pre-packaged , sterile antibiotic powder delivery system comprising:a container having a generally cylindrical body with a bottom, a sidewall extending upwardly from the bottom and a mouth at the top of the container;a measured dosage of an antibiotic powder disposed within the container; anda sieve top attached to the mouth of the container, the sieve top having a plurality of holes with a diameter;wherein the container with the measured dosage disposed within the container and the sieve top attached to the mouth of the container are sealed as a unit in a sterile packaging.2. The antibiotic powder delivery system of claim 1 , wherein the sieve top is removably attached to the mouth of the container.3. The antibiotic powder delivery system of claim 2 , wherein the sieve top has a plurality of threads and the mouth of the container has a plurality of threads such that the sieve top can be threadably engaged with the mouth of the container.4. The antibiotic powder delivery system of claim 1 , wherein the diameter of the plurality of holes is adjustable.5. The antibiotic powder delivery system of claim 1 , wherein the diameter of the holes is less than 0.5 mm.6. The antibiotic powder delivery ...

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Номер записи: 90
13-02-2014 дата публикации

Connection device for use in the negative pressure treatment of wounds

Номер: US20140046278A1
Автор: Axel Eckstein, Cornelia Wolf, Pierre Croizat
Принадлежит: Paul Hartmann AG

A connection device for use in the negative pressure therapy of wounds, includes a flexible conduit having at least two lumens and being constructed for impingement with negative pressure and/or fluid media; a coupling body made of an elastomeric flexible material, and non-detachably molded onto a wound-side end section of the conduit and being constructed for arrangement on a negative pressure bandage which covers the wound and seals the wound against the atmosphere, wherein the conduit communicates with a wound space through at least one opening in the coupling body; and a fluid inlet section for insertion through an opening in the negative pressure bandage into the wound space. The fluid inlet section is formed on the coupling body and protrudes over a walling of the coupling body, which walling faces the negative pressure bandage. The fluid inlet section is fluidly connected interiorly of the coupling body with a further lumen for delivering a fluid medium. The further lumen is formed inside the conduit or by a fluid delivery line leading to the coupling body.

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Номер записи: 91
13-02-2014 дата публикации

LIQUID MEDICAMENT APPLICATOR

Номер: US20140046280A1
Автор: HARADA Yasuhiro, HAYASHI Takashi, TAJIMA Masahiro, Uno Tomoko
Принадлежит: R-TECH UENO LTD

The present invention provides an applicator, which holds an intended quantity of liquid medicament and applies the same to skin or mucous membrane without wasting. The applicator comprises a grip portion for grasping; a neck portion , which can be elastically deflected, continuous from the grip portion ; and a head portion , having a slit for holding the liquid medicament supplied, continuous from the neck portion . When the head portion is pressed against the skin or the mucous membrane, the liquid medicament is applied there while the neck portion is elastically deflected. 1. An applicator for applying liquid medicament , comprising:a grip portion for grasping,a neck portion, which can be elastically deflected, continuous from the grip portion, anda head portion, having a slit for holding the liquid medicament supplied, continuous from the neck portion,wherein when the head portion is pressed against a target area, the liquid medicament is applied to the target area while the neck portion is elastically deflected.2. The applicator for applying liquid medicament according to claim 1 , wherein thickness of the neck portion is made gradually thinner from the grip portion toward the head portion.3. The applicator for applying liquid medicament according to claim 1 , wherein a rib claim 1 , which prevents drop down of the liquid medicament claim 1 , is provided at periphery of the head portion.4. The applicator for applying liquid medicament according to claim 2 , wherein a rib claim 2 , which prevents drop down of the liquid medicament claim 2 , is provided at periphery of the head portion. The present invention relates to an applicator for applying liquid medicament, which can be suitably used for applying liquid medicament to the skin around eyelashes, other skins, lip, mucous membranes in mouth, and so.The patent publication 1 discloses an applicator for applying liquid medicament of growing and fostering eyelashes. This applicator has a brush of resin bristles at ...

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Номер записи: 92
20-02-2014 дата публикации

COMPRESSED ARTICLES WITH MICROENCAPSULATION

Номер: US20140048436A1
Автор: SPECTOR DONALD
Принадлежит:

A compressed article of hygiene is formed by a compressed cloth that has been compressed by dehydration or vacuum pressure into a coin shape and that is expandable upon contact with a liquid, and a plurality of microencapsulated beads containing a material. The microencapsulated beads are attached and embedded in the compressed cloth. Upon contact with water, expansion of the compressed cloth is unconstrained, and the compressed cloth when expanded has a shape of a facial mask with openings for eye, nose and mouth. The material is a facial treatment material that hardens upon drying. 1. A compressed article of hygiene consisting of:a compressed cloth that has been compressed by dehydration or vacuum pressure into a coin shape and that is expandable upon contact with a liquid; anda plurality of microencapsulated beads containing a material, the plurality of microencapsulated beads being attached to the compressed cloth,so that, upon contact with water, expansion of the compressed cloth is unconstrained, and wherein the compressed cloth when expanded has a shape of a facial mask with openings for eye, nose and mouth, and wherein the material is a facial treatment material that hardens upon drying.2. The article of claim 1 , wherein the material is released from the beads upon expansion of the cloth in the liquid.3. The article of claim 1 , wherein the liquid comprises water.4. The article of claim 1 , wherein the material contains clay.5. The article of claim 1 , wherein the article is printed with a pattern or design.6. A collection of compressed articles according to claim 1 , wherein the articles are sealed in a strip of packaging such that each article is separable from the other articles without exposing the other articles to air.7. The collection according to claim 6 , wherein the strip contains sealed seams between the articles claim 6 , and a perforation extends along each seam. The present application is a continuation-in-part of U.S. patent application Ser. ...

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Номер записи: 93
20-02-2014 дата публикации

Disposable and portable garment for treating hands or feet

Номер: US20140052080A1
Автор: Gibson Lois, Heindl Carol L.
Принадлежит:

The present invention is a disposable garment, such as a glove, a sock, or a shoe, for treating foot or hand inflammation or disease. In a preferred embodiment, the garment comprises a flexible outer cover that is nonporous and an inner layer closely adhered to the inside of the outer cover. The outer cover may preferably have a flexible closure at the level of the ankle or wrist, arranged such that liquids will be retained therein. The inner layer serves as a reservoir for a selected therapeutic product, and preferably comprises a bladder. Preferably, the bladder has a perforation, and may be disposed within the inner layer in a position allowing a user to apply pressure to bladder with his foot or hand. A therapeutic product in liquid form is stored within the reservoir, and is released upon application of pressure by the user's foot or hand. 1. A disposable garment that comprises:(1) a flexible outer cover that is nonporous, having a flexible closure at the level of the ankle or wrist, arranged such that liquids will be retained therein,(2) an inner layer closely adhered to the inside of the outer cover, said inner layer serving as a reservoir for therapeutic product, and said inner layer comprising a bladder,wherein said bladder has a perforation, and wherein said bladder is disposed within such inner layer in a position allowing a user to apply pressure to said bladder with user's foot or hand, and(3) a therapeutic product in liquid form stored within the reservoir, wherein said therapeutic product is released upon application of pressure by the user's foot or hand.2. The garment of claim 1 , comprised of a shoe.3. The garment of claim 1 , comprised of a sock.4. The garment of claim 1 , comprised of a glove.5. A method of treating at least one of inflamed feet claim 1 , inflamed hands claim 1 , calluses claim 1 , or cracks claim 1 , comprising providing a garment in accordance with to a user suffering from at least one of such conditions.6. A method of making a ...

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Номер записи: 94
20-02-2014 дата публикации

Integrated insulin delivery system with continuous glucose sensor

Номер: US20140052094A1
Автор: Aarthi Mahalingam, Apurv Ullas Kamath, James H. Brauker, John Michael Dobbles
Принадлежит: Dexcom Inc

Systems and methods for integrating a continuous glucose sensor 12 , including a receiver 14 , a medicament delivery device 16 , a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

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Номер записи: 95
27-02-2014 дата публикации

Implement for a Skin Treatment Device

Номер: US20140058300A1
Автор: Gliemroth Frank Roland, Kawerau Jochen, Maichel Michael, Stoerkel Ulrich, Ungemach Christof
Принадлежит: Braun GmbH

A brush implement for the use with a skin treatment device, the brush implement having bristles of a first type and bristles of a second type, wherein the bristles of the first type are longer than the bristles of the second type and are positioned closer to the outer contour of the brush implement and the bristles form at least three distinguishable sectors. 1. A brush implement for the use with a skin treatment device , the brush implement having an outer contour and comprising bristles of a first type and bristles of a second type , wherein the bristles of the first type are longer than the bristles of the second type and are positioned closer to the outer contour of the brush implement and the bristles form at least three distinguishable sectors.2. A brush implement according to claim 1 , further comprising bristles of a third type that differ from the bristles of the first type and the bristles of the second type at least in one of the following characteristics: length claim 1 , diameter claim 1 , material claim 1 , rigidity claim 1 , or flexibility.3. A brush implement according to claim 2 , wherein the bristles of the third type have the same length as the bristles of the second type.4. A brush implement according to claim 1 , wherein each bristle is formed from a plurality of filaments.5. A brush implement according to claim 1 , wherein the sectors each have the same arrangement of bristles.6. A brush implement according to claim 1 , wherein the sectors have a discrete rotation symmetry such that each of the sectors can be essentially exactly overlaid onto another sector by a rotation in clockwise or counter-clockwise rotation around the symmetry axis.7. A brush implement according to claim 1 , wherein each sector has a row of bristles of the first type arranged along a convex contour claim 1 , which contour originates in the center of the brush.8. A brush implement according to claim 1 , wherein a portion of the outer contour of the bristle arrangement only ...

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Номер записи: 96
27-02-2014 дата публикации

METHODS AND DEVICES FOR DESMOPRESSIN DRUG DELIVERY

Номер: US20140058313A1
Автор: Fein Seymour H., Herschkowitz Samuel
Принадлежит: ALLERGAN, INC.

Disclosed are devices for urine voiding postponement, and methods for treating conditions such as central diabetes insipidus, enuresis, nocturia, urinary frequency or incontinence. The devices deliver a desmopressin flux through the skin of a patient in a low dose amount just necessary to achieve a desired anti-diuretic effect without undesirable side effects such as hyponatremia. The devices are designed to permit a state of normal urinary production to return quickly after the desmopressin flux is terminated. 113-. (canceled)14. A device for modulating urine production in a patient , the device comprising:a) a depot containing a solution of desmopressin in a pharmaceutically acceptable carrier,b) an interface member in fluid communication with the depot for application to the skin of a patient; i) sufficient to establish and maintain a desmopressin concentration in the blood of the patient within the range of about 0.2 to 5 pg/ml and', 'ii) insufficient to induce a desmopressin concentration in the blood of the patient greater than about 5 pg/ml., 'c) means for delivering the desmopressin solution from the depot to the interface member and intradermally or transdermally to the blood of a patient at a flux rate15. The device of claim 14 , wherein the flux rate is between about 5 and 35 ng/hr (5000 to 35 claim 14 ,000 pg/hr).16. The device of claim 14 , wherein the flux rate is between about 10-20 ng/hr.17. The device of claim 14 , wherein the flux rate is between about 5-15 ng/hr.18. The device of claim 14 , wherein the flux rate is about 10 ng/hr.19. The device of claim 14 , wherein the means for delivering the desmopressin solution establishes a first claim 14 , higher flux rate to establish a desmopressin concentration in the blood of a patient within the range and a second claim 14 , lower flux rate to maintain the concentration.20. The device of claim 19 , further comprising a timer for triggering flux rate change.21. The device of claim 14 , wherein the ...

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Номер записи: 97
27-02-2014 дата публикации

Cleansing Device and Method

Номер: US20140058342A1
Автор: Chantal Jones, Lynda Trudel, Olivia Jones
Принадлежит: Individual

An external device for applying a substance to the perineum comprises: a bottom wall; and an elastic side wall extending from the bottom wall; wherein said bottom wall and side wall together form an open cup-shaped body for holding the substance.

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Номер записи: 98
13-03-2014 дата публикации

Multi-component method for regenerative repair of wounds implementing photonic wound debridement and stem cell deposition

Номер: US20140074068A1
Автор: Joseph Bielitzki, Richard Ty Olmstead
Принадлежит: Individual

A new and useful method for regenerative repair of wounds implementing photonic wound debridement and stem cell deposition is presented which consists of a Wound Assessment and Debridement, Wound Infrastructure Building, and Cell Deposition phases. The present invention allows structured regenerative repair of the wound, utilizes robotic systems to inspect, define and debride the wound, and prints an extracellular matrix on the prepared wound site which speeds healing using developing stem cell technologies. This device is believed to be useful in hospitals and clinics, wherein patients with wounds related to skin trauma such as burns, infection, or melanoma are present. An example of a theatre of use is a children's burn ward. This device is also believed to be useful in military hospitals which receive soldiers injured in combat.

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Номер записи: 99
20-03-2014 дата публикации

Biodegradable Multilayer Constructs

Номер: US20140081070A1
Автор: Martin George R., McMurtry David H., Paukshto Michael V.
Принадлежит: Fibralign Corporation

Embodiments of the present invention relate generally to the field of tissue repair and regeneration. More specifically embodiments of present disclosure relate to devices or constructs and methods to prepare various devices or constructs useful in directing cellular repair and controlling tissue regeneration to prevent or minimize postsurgical or post traumatic adhesions, excessive scars and/or fibrotic reactions of injured tissues. 1. A multilayer construct comprising: at least one cross-linked fibrillar nanoweave biopolymer layer.2. The multilayer construct according to wherein the fibrillar nanoweave biopolymer layer enables cell guidance and tissue regeneration.3. The multilayer construct according to wherein the fibrillar nanoweave biopolymer layer stimulates non-scarring phenotype for adherent cells.4. The multilayer construct according to wherein the construct is a biocompatible and biodegradable implant.5. The multilayer construct according to wherein the fibrillar nanoweave biopolymer layer is made from collagen.6. The multilayer construct according to wherein the collagen is comprised of medical grade monomeric collagen solution or gel.7. The multilayer construct according to wherein the fibrillar nanoweave biopolymer layer is comprised of oriented fibrillar biopolymer material.8. The multilayer construct according to wherein the fibrillar nanoweave biopolymer layer has no pores with diameter greater than 0.5 micron.9. The multilayer construct according to further comprising a second biopolymer layer with the pore diameter in the range 10-500 micrometers that permit repair cells to infiltrate said layer.10. A multilayer construct comprising: at least two fibrillar nanoweave biopolymer layers attached by intermediate biodegradable layer.11. The multilayer construct according to where the intermediate layer has a rate of degradation higher than at least one nanoweave biopolymer layer under physiological conditions.12. The multilayer construct according to ...

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Номер записи: 100