ИНЪЕКТОР МНОГОКАМЕРНЫЙ

Изобретение относится к медицинской технике, а именно к устройствам для введения медицинского препарата. Устройство выполнено в виде многокамерного шприца, включающего: три или более камер, расположенных параллельно друг другу и параллельно центральной оси; отдельные поршни для каждой из трех или более камер и вращающийся корпус выпускного отверстия, соединенный с тремя или более камерами таким образом, что как минимум часть корпуса выпускного отверстия вращается вокруг центральной оси, обеспечивая жидкостную связь выпускного отверстия с одной из трех или более камер с одновременным перекрытием поступления содержимого из остальных камер. При этом многокамерный шприц дополнительно содержит съемный защитный колпачок, закрывающий выпускное отверстие, причем в защитном колпачке предусмотрена возможность хранения губчатого материала и одной или более игл, прикрепленных к защитному колпачку посредством гнезд с фрикционной посадкой. 2 н и 25 з.п. ф-лы, 8 ил.

Device with a daily medicament depot for low-pain injection

The invention relates to a device with a daily medicament depot for low-pain injection. The device filled with a medicament can also be worn on the body, has a low weight and is built on the fountain-pen principle. It comprises a dust-proof, thermally insulating casing with an exchangeable, multi-layer, disinfecting, sterile fumigation pad, an inert glass or plastic cylinder with an outside that is firmly gripped, a teflon-coated piston rod and a teflon-coated metal cone, as well as a tuned optical and acoustic display system for the individual determination of the amount to be injected. The tuned optical system has a graduation in units of medicament on the unilaterally flattened threaded spindle which correlates with the medicament volume of the syringe. The acoustic system is a bayonet closure with a marking spring extending in a sound space on the unilaterally flattened threaded spindle. The fumigation pad is also used to disinfect the injection site. The puncturing direction can be ...

Inoculating instrument

... 802,351. Hypodermic injection appliances. HABER, C. Oct. 13, 1954 [Oct. 14, 1953; Sept. 11, 1954], No. 29563/54. Class 81 (2). The needle of a hypodermic syringe is moved sideways to and from its operative position on the syringe to avoid sucking back contained fluid, and is held in position by a spring-loaded lever. An attachment for fitting to the taper of an ordinary syringe comprises a body part 1 carrying a bell-crank 2 which is spring-loaded by a leafspring 4 so as to bear down, at its bifurcated end 15, on the flat base 8 of the needle mount, so that this is held in liquid-tight contact with a complementary insert 9. Locating studs are provided to ensure correct alignment of the bores. It is intended that the needles shall be stored horizontally after sterilization and, by compressing the spring 4, by thumb pressure on the lever 2, the needle can be placed in position and withdrawn from its holder without being touched. A spring 5 is provided to exert a lateral thrust to eject a ...

Hypodemic jet injection kit.

Hypodermic jet injection kit

A hypodermic injection system particularly for use in mass immunizations having a handpiece with a grasping mechanism for holding ampules filled with injectate, a plunger for driving into the ampule to discharge the injectate in an injection process, an injection spring mechanism for driving the plunger, a motor and/or manual mechanism for cocking the injection spring mechanism, and an ampule ejection mechanism for ejecting ampules after use under control of a release mechanism. Ampules can be loaded, used and ejected without contact by the user of the system or the patient being injected. Also disclosed are a filling station for filling ampules through their injection orifices, and an arming device for setting the injection spring. Ampules are disclosed having a piston which is drivable towards an orifice to discharge injectate through the orifice. Ampules are also disclosed having enlarged proximal portions for easy grasping by the grasping mechanism of the injector. Ampules are further ...

Hypodemic jet injection kit.

Hypodemic jet injection kit.

ANGIOGRAPHY SYRINGE WITH MULTIPLEREDUNDANT PROCESSORS

VORGEFÜLLTE SYRINGE OR KARPULE FOR MEDICAL PURPOSES

AUFBEWAHRUNGSBEHALTER FUR KANULEN

MULTI-CHAMBER AMPUL FOR SPENDING A FROM SEVERAL SUBSTANCES OF EXISTING MIXTURE

METHOD FOR MANUFACTURING A DEVICE FOR OPHTHALMI TREATMENTS

Intravitrealinjektioninstrument with UV C disinfection system

Die vorliegende Erfindung bezieht sich auf einen Aufsatz für Spritzen mit einem zylindrischen, teleskopartig zurückgleitenden Element (6), das einen von der Umgebung abgetrennten Raum zur Injektionsfläche schafft, sowie einer UV-Lichtquelle (7), die mittels der emittierten Strahlung den geschaffenen Raum (8) zusätzlich desinfiziert.

ANGIOGRAPHY SYRINGE WITH MULTIPLEREDUNDANT PROCESSORS

PROCEDURE AND DEVICE FOR CONTROLLABLE STERILIZATION, DESTRUCTION AND A PACKAGING OF MEDICAL WASTE MATERIALS.

SUBKUTANINJEKTIONSSPRITZE WITH SELECTIVELY RETRACTABLE NEEDLE

AUFBEWAHRUNGSBEHALTER FUR KANULEN

Cleaning device and method for using the same

A cleaning device for cleaning a connector comprising a lumen and an inner threaded surface. The cleaning device includes a cleaning body and a plunger body operably coupled to each other. The cleaning body includes a plurality of elongated cleaning swabs positioned separately apart from and in parallel to each other. The plurality of elongated cleaning swabs are operably rotatable about a connector lumen and in removable engagement with a connector inner threaded surface. The plunger body includes an elongated plug to removably engage the connector lumen. The cleaning body and the plunger body are translatably coupled along a common operational axis. The cleaning body and the plunger body are rotatably coupled with respect to each other about the common operational axis. The cleaning body is an integral structure.

Automatic injection and retraction syringe

CATHETER HEAD WITH CATHETER DRAIN IN DISCRETE ROTATIONAL POSITIONS

Multi-chamber injection device

A multi-chamber injection device includes multiple syringes. The multiple syringes may be arrayed in a circular, linear, or other format. In some implementations, a needle, port, or similar may be shared by all the syringes in configuration that allows only one syringe to deliver contents at a time while blocking the other syringes from delivering their respective contents. In some implementations, the syringes may be all stored in the same container. One or more of the chambers of a multi-chamber injection device may be preloaded with medication. Different medications may be loaded into different chambers. The medications may be selected to treat the same medical condition.

Hypodermic syringe with a selectively retractable needle

NEEDLELESS INJECTOR ACCESSORIES

A disposable nozzle for use on the discharge end of the barrel of a needleless injector is threaded onto the front end of a holder mounted in the barrel. A resilient detent extending outwardly at an acute angle from the inner wall of a recess in the rear end of the nozzle repeatedly enters and exits notches in a sleeve on the holder when the nozzle is mounted on the holder providing an audible signal that the nozzle has not been used. Reverse rotation of the nozzle during removal from the holder results in breaking of the detent. Thus, mounting of a used nozzle on the holder would not be accompanied by a signal that the nozzle is unused.

SELF-CLEANING NEEDLELESS CONNECTOR

A self-cleaning needleless connector may include a connector body defining a fluid passageway including an inlet and an outlet, a cover disposed over at least the inlet of the connector body, an access point disposed at an inlet end of the cover, where in a first position the inlet is within the cover and in an second position the inlet is extended beyond the cover and configured to receive a male luer, a reservoir containing a cleaning agent, and an abrasive surface located in the cover that is in fluid communication with the cleaning agent, where the abrasive surface and the cleaning agent are configured to contact an exterior surface of the inlet to create friction.

NEEDLELESS CONNECTOR AND ACCESS PORT DISINFECTION CLEANER AND ANTIMICROBIAL PROTECTION CAP

A protective cap having a first cap and a second cap that are removably coupled together for use in short-term and long-term antimicrobial treatment of needleless connectors and access ports of an infusion system. The instant invention further provides a protective cap having a first cap and a second cap that each coupled to a different surface of a component of an infusion system, such as a syringe. The instant invention further provides a strip containing a plurality of disposable protective caps.

GENERAL VIRUS CAUSE ELIMINATOR

General Virus cause eliminator. Allvirus 1. : This family of products was invented to eliminate the risk of needle Puncture infection at the source, namely the health care Provider (i.e., the needle user).

Porte-aiguilles pour aiguilles hypodermiques.

Einrichtung zum Reinigen von Injektionsspritzen

Seringue hypodermique

Injektionsspritze mit Sterilisator

Verfahren und Einrichtung zum Reinigen von Injektionsspritzen

Procédé de lavage mécanique d'éléments constitutifs d'instruments médicaux ,notamment de seringues hypodermiques et dispositif pour la mise en oeuvre de ce procédé

Hilfseinrichtung zum Reinigen und Trocknen der Bestandteile von Injektionsspritzen in einer Waschmaschine mit Umlauftrommel

Hilfsvorrichtung, die zur Aufnahme einer zerlegten Injektionsspritze bestimmt ist und die es ermöglicht, die Spritzenbestandteile maschinell zu reinigen

Ensemble pour piqûres hypodermiques

Impfbesteck

Vorrichtung zum Sterilisieren und sterilen Aufbewahren von Kanülen für Ampullenspritzen.

Procédé de lavage d'aiguilles de seringues hypodermiques et panier de lavage pour la mise en oeuvre de ce procédé

Nadellose Injektionsspritze

Machine à laver les seringues hypodermiques

Récipient cylindrique en métal léger pressé pour la stérilisation par chaleur sèche

Récipient cylindrique pour la stérilisation

Behälter zum Sterilisieren und zur sterilen Aufbewahrung medizinischer Instrumente

ACCESSORY STERILIZATION FOR INJECTION APPARATUS.

Injector

The present invention provides an injector having an excellent air-tightness and capable of being sufficiently sterilized with a plunger rod, which has a flange, mounted in the injector. The air-tightness is achieved by a back-stop function of the flange located at a position separated from a gasket toward the base end side. A gasket (3) is inserted into a barrel (2) from a base end opening (22) of the barrel (2), a plunger rod (4) is inserted into the barrel (2) to connect the front end of the plunger rod to the gasket (3), and a finger grip (5) is mounted to a flange (23). A disc section (45) is formed at that portion of the plunger rod which is separated from the gasket toward the base end side, and this enables the disc section to make contact with a hole edge (521) of the finger grip. A recessed communication opening (451) is formed in the outer peripheral edge of the disc section (45). In sterilization using hydrogen peroxide gas, the hydrogen peroxide gas entering an open space(26 ...

STORAGE BOX

ACCESSOIRE DE STERILISATION ET MONTURE POUR SUBSTANCE STERILISANTE

ACCESSOIRE DESTINE A UN APPAREIL D'INJECTION DU TYPE DANS LEQUEL LE LIQUIDE EST AMENE AU TRAVERS D'UNE AIGUILLE CREUSE. L'ACCESSOIRE COMPREND DES MOYENS 12 PERMETTANT DE STERILISER L'AIGUILLE 3 AVANT D'APPLIQUER CELLE-CI AU CHAMP D'INJECTION. L'ACCESSOIRE COMPREND UNE PREMIERE PARTIE 10 FIXEE A L'APPAREIL D'INJECTION ET UNE DEUXIEME PARTIE 11 COULISSANTE PORTANT LES MOYENS DE STERILISATION 12. UN RESSORT 22 MAINTIENT LES DEUX PARTIES ELOIGNEES. L'AIGUILLE PENETRE ET TRAVERSE LES MOYENS DE STERILISATION LORS DU MOUVEMENT RELATIF DES PREMIERE 10 ET DEUXIEME 11 PARTIES.

hypodermic Bulb-syringe

ACCESSORY OF STERILIZATION AND MOUNTING FOR STERILIZING SUBSTANCE

CASSETTE ASEPTISES ITEMS FOR STERILIZATION, COMPRISING A PERFORATED ENCLOSURE

SYRINGE

Conjunto para injeção hipodérmica por jato

DISPOSITIVO PARA TRATAMENTOS OFTÁLMICOS E MÉTODOS PARA PRODUÇÃO DO REFERIDO DISPOSITIVO

Injection device for drug delivery and packaging for the injection device

An injection device is provided, including a syringe having a barrel and a flange and a backstop configured to be coupled with the syringe adjacent to the flange. The backstop includes an inner surface generally extending around at least a portion of the syringe, wherein the inner surface includes at least one protrusion extending away from the inner surface and configured to engage the flange and/or the barrel to permit or promote airflow through a space between the inner surface and the syringe.

PACKING ALLOWING GAS STERILISATION

This invention relates to a packing for a medical device comprising a fabric or non-woven based layer e.g. provided with an adhesive surface or another layer for securing a device to the skin of a patient. The packing comprises at least one layer (1 ) impenetrable to gas which layer has at least one opening (5), said opening (5) is covered by a filter layer (11 ) which is permeable for sterilization gas, wherein the filter layer (11 ) is a part of the medical device to be sterilised. According to one embodiment the part of the filter layer (11 ) surrounding the opening (5) is placed in close contact with two opposing parts of the packing where a first part of the packing (1 ) which is provided with the opening (5) is in close contact with a first side of the filter layer (11 ) and the second part of the packing (8) is in close contact with the opposite side of the filter layer (11 ).

LOCAL DISINFECTION FOR DRUG DELIVERY SYSTEM

Apparatus and a method are presented, including disinfecting a disinfection chamber () that is defined between (i) a prefilled therapeutic substance reservoir () and (ii) a sterile fluid path () disposed within a therapeutic substance delivery device (). The sterile fluid path includes a needle () at an upstream end () of the sterile fluid path and an injection assembly () at a downstream end () of the sterile fluid path. Subsequently to disinfecting the disinfection chamber, the disinfection chamber and then the reservoir are penetrated with the needle. Other applications are also described. 1. A method comprising: 'the sterile fluid path comprising a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path; and', 'disinfecting a disinfection chamber that is defined between (i) a prefilled therapeutic substance reservoir and (ii) a sterile fluid path disposed within a therapeutic substance delivery device,'}subsequently, penetrating the disinfection chamber and then the reservoir with the needle.2. The method according to claim 1 , wherein the step of disinfecting the disinfection chamber is performed following a user of the therapeutic substance delivery device engaging the prefilled therapeutic substance reservoir with the therapeutic substance delivery device claim 1 , wherein the disinfection chamber is defined when the prefilled therapeutic substance reservoir becomes engaged with the therapeutic substance delivery device.3. The method according to claim 1 , wherein the step of disinfecting the disinfection chamber is performed following a user of the therapeutic substance delivery device removing the therapeutic substance delivery device from commercial packaging claim 1 , wherein the prefilled therapeutic substance reservoir and the therapeutic substance delivery device are engaged with one another inside the commercial packaging.4. The method according to claim 1 , wherein disinfecting the ...

Apparatus and method for sterilizing, destroying and encapsulating medical implement wastes

Apparatus and method for sterilizing and encapsulating contaminated waste particularly medical implement waste in which a volume of thermoplastic compound having a melting point temperature-calibrated at a value which corresponds substantially to the temperature at which all biological contamination is rendered sterile substantially on contact, and impregnating a space containing contaminated waste items with the liquid compound and thereafter cooling the mass to its solidified phase while containing it against protrusion of any waste item.

Fitments for injection devices

In order to minimize the risk of infection when a large number of animals are injected with the same needle, the injecting gun is provided with a stainless steel sleeve which surrounds the needle. The sleeve comprises a first tube attached to the needle connecting body and a second tube telescopically slidable within the first tube against a spring. A detachable plastics cap incorporating a sterilizing substance is fitted on the free end of the second tube. In use of the gun to inject an animal, the cap is applied to the proposed site of injection and pressure is applied to the gun to cause the tubes to telescope, so that the point of the needle passes through the sterilizing substance and punctures the skin of the animal. On releasing the applied pressure, the point of the needle will be withdrawn from the animal and will pass back through the sterilizing substance under the action of the spring.

Method and apparatus for manufacturing, filling and packaging medical devices and medical containers

Medical devices such as medical containers can be formed of glass and annealed which produces a clean device having a low bio-burden, or formed by plastic molding which produces a clean device. The clean devices are immediately transferred to a controlled environment such as a clean room or localized area to avoid the need to maintain cleanliness levels in an entire room. Syringe tip closures can be introduced into the housing assembly, where syringe barrels and tip closures are cleaned with filtered ionized air and the tip closures are coupled to the barrels. The syringe barrels can be filled with a substance and a closure member attached. While still in the housing assembly the syringe barrels can be formed into an array and placed in a clean outer container, which is then closed and sealed.

Method and apparatus for delivering a therapeutic substance through an injection port

Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.

Local disinfection for prefilled drug delivery system

A therapeutic substance delivery device is provided for delivering therapeutic substance to the subject. A sterile fluid path includes a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path. The delivery device engages with a prefilled therapeutic substance reservoir, such that a disinfection chamber is defined between the sterile fluid path and the reservoir. The needle penetrates the disinfection chamber and subsequently the reservoir when the therapeutic substance delivery device and the reservoir are engaged with one another. A disinfection assembly is disposed within the delivery device and configured to disinfect the disinfection chamber prior to the needle penetrating the disinfection chamber. Control circuitry activates the disinfection assembly, terminates the activation of the disinfection assembly, and subsequently drives the needle to penetrate the disinfection chamber and subsequently the reservoir.

Surface Decontamination of Prefilled Containers in Secondary Packaging

Methods and systems for the terminal sterilization and surface decontamination of prefilled containers containing sensitive drug products, such as biotech drug products that are otherwise temperature or radiation sensitive, and thus not suitable for terminal sterilization by classical methods involving steam or gamma rays. The methods and systems are especially suited for prefilled containers in secondary packaging. Methods include terminal sterilization by exposing prefilled containers in secondary packaging to tunable-beta radiation and further include terminal sterilization by exposing prefilled containers to controllable vaporized-hydrogen peroxide, including application of measures to reduce or prevent diffusion of vaporized-hydrogen peroxide into prefilled containers.

FLOW COMMUNICATION UNIT WITH PRESERVATIVE

An assembly comprises a sealed drug reservoir unit, a subcutaneous flow conducting device in the form of a needle unit or an infusion set, and a flow communication unit. The flow communication unit comprises a proximal hollow needle adapted to penetrate a needle-penetrable septum of the reservoir, a first flow-way inflow communication with the proximal needle and comprising a pressure-controlled valve, a second flow-way in flow communication with the first flow-way, an amount of preservative arranged to react with a substance received by the second flow-way, and distal flow communication means adapted to provide flow communication between the second flow-way and the needle unit. A combined flow way can be established between the reservoir and the needle unit via the first and second flow-ways when the units are connected. The valve is controlled to open when the reservoir is pressurized, the preservative being provided to react with substances introduced to the second flow way via the needle ...

Integrated Disinfection Device

Syringe tip caps are described herein. Such syringe tip caps may include a cup, a cap, a locking feature, a peelable seal and an absorbent material. The cap having locking features and a chamber appropriately sized to adapt to and interlock with an annular wall of the cup.

Hypodermic injection system

A hypodermic injection system particularly for use in mass immunizations having a handpiece with a grasping mechanism for holding ampules filled with injectate, a plunger for driving into the ampule to discharge the injectate in an injection process, an injection spring mechanism for driving the plunger, a motor and/or manual mechanism for cocking the injection spring mechanism, and an ampule ejection mechanism for ejecting ampules after use under control of a release mechanism. Ampules can be loaded, used and ejected without contact by the user of the system or the patient being injected. Also disclosed are a filling station for filling ampules through their injection orifices, and an arming device for setting the injection spring. Ampules are disclosed having a piston which is drivable towards an orifice to discharge injectate through the orifice. Ampules are also disclosed having enlarged proximal portions for easy grasping by the grasping mechanism of the injector. Ampules are further ...

Соupling fоr аn аutо-injесtiоn dеviсе

А соupling fоr sеlесtivеlу sесuring а spring tо а plungеr is prоvidеd. Тhе соupling hаs а first еnd dеfining а spring rеst fоr rесеiving thе spring аnd а sесоnd еnd dеfining а shоuldеr. Тhе shоuldеr is mоvеаblе tо а first pоsitiоn intо соntасt with thе plungеr аnd tо а sесоnd pоsitiоn оut оf соntасt with thе plungеr. Тhе shоuldеr is nоrmаllу in thе sесоnd pоsitiоn аnd is rеsiliеntlу mоvеаblе tо thе first pоsitiоn.

Соupling fоr аn аutо-injесtiоn dеviсе

А соupling fоr sеlесtivеlу sесuring а spring tо а plungеr is prоvidеd. Тhе соupling hаs а first еnd dеfining а spring rеst fоr rесеiving thе spring аnd а sесоnd еnd dеfining а shоuldеr. Тhе shоuldеr is mоvеаblе tо а first pоsitiоn intо соntасt with thе plungеr аnd tо а sесоnd pоsitiоn оut оf соntасt with thе plungеr. Тhе shоuldеr is nоrmаllу in thе sесоnd pоsitiоn аnd is rеsiliеntlу mоvеаblе tо thе first pоsitiоn.

СПОСОБ АСЕПТИЧЕСКОЙ СБОРКИ МНОГОКОМПОНЕНТНОГО МЕДИЦИНСКОГО УСТРОЙСТВА И НАБОР ДЛЯ ЕГО ОСУЩЕСТВЛЕНИЯ

Группа изобретений относится к области асептической сборки многокомпонентного (составного) медицинского устройства. Способ асептической сборки многокомпонентного медицинского устройства характеризуется тем, что: а) подготавливают первый компонент медицинского устройства, находящийся в первом контейнере, и второй компонент медицинского устройства, находящийся во втором контейнере, причем каждый из отдельных контейнеров имеет разрываемый участок, б) стерилизуют первый компонент в первом контейнере первым методом стерилизации, а второй компонент во втором контейнере - вторым методом стерилизации, причем первый и второй методы стерилизации выбирают отличными друг от друга из группы, состоящей из газовой стерилизации, радиационной стерилизации и термической стерилизации, в) соединяют первый и второй контейнеры, совмещая их разрываемые участки друг над другом в месте, асептически изолированном от окружающей среды, г) перемещают один из компонентов сквозь разрываемые участки и асептически собирают ...

МЕДИЦИНСКОЕ ИНЪЕКЦИОННОЕ УСТРОЙСТВО С ОЧИЩАЮЩЕЙ КАМЕРОЙ

Изобретение относится к медицинской технике, а именно к инъекционному устройству, предназначенному для инъецирования жидкого лекарственного препарата и содержащему: корпусной блок (110, 120), поддерживающий картридж, установленный в нем без возможности извлечения и имеющий внутреннюю камеру, в которой содержится жидкий лекарственный препарат, подлежащий инъецированию, и присоединенную к картриджу игольчатую канюлю многократного применения. Устройство содержит также сборный чехол иглы, снабженный очищающей камерой, в которой содержится агент, очищающий между последовательно выполняемыми инъекциями по меньшей мере дистальный кончик игольчатой канюли. Сборный чехол иглы установлен с возможностью перемещения по оси в проксимальном направлении относительно корпусного блока из первой позиции во вторую в результате поворота по меньшей мере одной своей части. При этом в первой позиции дистальный кончик игольчатой канюли находится внутри очищающей камеры, где он очищается, а во второй позиции дистальный ...

УСТРОЙСТВО ДЛЯ ОФТАЛЬМОЛОГИЧЕСКОЙ ТЕРАПИИ И СПОСОБЫ ПОЛУЧЕНИЯ ТАКОГО УСТРОЙСТВА

... 1. Устройство для офтальмологической терапии, отличающееся тем, что оно содержит упаковочный футляр (9), образующий камеру (9а) футляра внутри него, и шприц (2), помещенный в камеру (9а) футляра, причем шприц (2) наполнен стерильной жидкостью, которая может вводиться внутрь глазного яблока, выбранная из числа препаратов семейства перфторуглеродов. ! 2. Устройство для офтальмологической терапии по п.1, отличающееся тем, что шприц (2) содержит: ! полый трубчатый корпус (3), имеющий открытый первый конец (3а) и второй конец (3b); ! заглушку (7), герметично помещенную с возможностью частичного скольжения в полый трубчатый корпус (3) через первый конец (3а); ! колпачок (8), приспособленный для закрывания второго конца (3b) полого трубчатого корпуса; ! причем заглушка (7) и колпачок (8) ограничивают локализационную камеру (2а), содержащую жидкость, в трубчатом корпусе (3). ! 3. Устройство по п.2, отличающееся тем, что оно также содержит люэровскую соединительную насадку, связанную со вторым концом ...

Implantable biosensor and drug administration arrangement and sterilisation method

An implantable biosensor and drug administration arrangement which is to ensure combined recording of measured values and administration of drugs and to which high biocompatibility is imparted by a sterilisation treatment according to the invention. The working electrode represents the active part as an enzyme and measurement electrode and is designed as a puncturing needle, while the reference electrode is designed as an infusion cannula and/or infusion pump. The working electrode is stored until use for at least 70 hours in a solution containing H2O2 in the order of magnitude of 0.6% and during this time it is exposed to gamma radiation with a maximum dose of 6.5 KGy. ...

System zum Verabreichen eines flüssigen Medikaments

Die Erfindung betrifft ein System mit einem Medikamenten-Reservoir (1) für eine Medikamenten-Dosiervorrichtung zum Verabreichen eines flüssigen Medikaments und einem das flüssige Medikament aufweisenden Medikamenten-Vorratsbehälter (2), dadurch gekennzeichnet, dass außerdem eine Befüllvorrichtung (3) zum automatischen Befüllen des Medikamenten-Reservoirs (1) mit dem Medikament aus dem Medikamenten-Vorratsbehälter (2) vorgesehen ist. Das erfindungsgemäße System zum Verabreichen eines Medikaments hat den Vorteil, dass eine sichere und einfache Befüllung des Medikaments erfolgen kann.

Vorrichtung für subkutane Verabreichung von Medikamenten

Vorrichtung zum Handhaben von in einem nach oben offenen Behälter angeordneten, befüllbaren, rohrförmigen Gegenständen

Verfahren zur kontinuierlichen Messung, Erfassung und Regelung des Stützdrucks sowie Vorrichtung zur Durchführung des Verfahrens

Das erfindungsgemäße Verfahren dient zur kontinuierlichen Messung, Erfassung und Regelung des Stützdrucks bei der Sterilisierung von vorzugsweise in Behältnissen (4) mit verschiebbarem Verschlußmechanismus (3) angeordneten pharmazeutischen Produkten. Während der Sterilisierung wird der Druck im Inneren des durch den Verschlußmechanismus (3) abgeschlossenen Behältnisses (4) entweder unmittelbar über einen mit dem Inneren des Behältnisses (4) in Verbindung stehenden Drucksensor (6) erfaßt oder über einen die Verschiebung des Verschlußmechanismus (3) aufgrund der Druckdifferenz zwischen dem Inneren und dem Äußeren des Behältnisses (4) erfassenden Sensor (5) ermittelt. Aus diesem Meßsignal wird eine Regelgröße gebildet, über die der von außen auf das Behältnis (4) einwirkende Stützdruck in der Weise angepaßt wird, daß der Innendruck und der Stützdruck gleich oder zumindest nahezu gleich sind.

Vorrichtung zum Reinigen und Trocknen von rohrfoermigen Gegenstaenden wie Subkutannadeln

Improvements in cleansing of component elements of medical instruments

... 1,011,756. Washing component elements of medical instruments. A. CHARPILLOZ, [trading as ETABLISSMENTS ACIC ARNOLD CHARPILLOZ]. Aug. 17, 1962 [Aug. 25, 1961; Nov. 20, 1961], No. 31737/62. Drawings to Specification. Heading B8T. Syringe elements are disposed in the rotary drum of an automatically controlled domestic clothes washing machine, and each element is maintained in a fixed position with respect to the drum. The elements are supported in cages which are secured in the rotary drum in the manner described in Specification 1,011,755.

CONTAINER FOR STORING DISPOSABLE HYPODERMIC SYRINGES

A container for storing a disposable hypodermic syringe provides protection for a syringe and needle, is capable of holding a sterilizing or antiseptic solution, and allows otherwise disposable hypodermic syringes to be reused as long as they remain in satisfactory condition. The container is formed so that the upper portion of a disposable syringe will be held within a cylindrical upper portion 20 of the container with the syringe handle 33 resting on a shelf 22 and such that the needle will not be in danger of striking the base 16 or body of the container. The body of the container is generally frustoconical 18 in shape so that in the event of the container being tipped only the barrel 32 of the syringe, and not the needle 34, will possibly strike the body of the container. The container is made of a durable, unbreakable, plastics material that is easily cleaned and can hold most types of conventional antiseptic or sterilizing solutions, e.g isopropal alcohol. A cap 12 screws onto the ...

STERILE NEEDLE PROTECTOR

A sterile needle protector comprising a cover is a hypodermic and butterfly needle storage and protection system which uses surface tension as the force to control the position of the lubricating and sterilising liquid within a specially shaped cylinder with a blank end. ...

Improvements in and relating to cases for hypodermic syringes

... 721,375. Hypodermic syringes. DAVIS, R. W. March 26, 1953 [March 26, 1952], No. 7799/52. Class 81 (2). A case for a hypodermic syringe 7 has a shouldered portion 5, or ledge, which engages the finger flange 6 on the syringe to support the latter. The case is extended upwards and is .closed by a cap 4, a wad of wool 9 being pressed down on the syringe. Apertures 14, 15 are provided in the body and cap respectively, which are aligned during sterilisation, to allow the entry of sterilising atmosphere, and which are closed by turning the cap, immediately the case is removed from the autoclave.

Ejector package

... 938,777. Hypodermic syringes. BRUNSWICK CORPORATION. Sept. 11; 1961, No. 32514/61. Class 81 (2). [Also in Group XVII] A package for hypodermic syringes comprises a main body section or sleeve 12, a cap 13 preferably sealed as at 37 and a reciprocable closure member 14 which houses the needle 27 and hub 26 of the syringe. The member 14 is ribbed at 19 to facilitate manipulation and is closed at its lower end 20 by a fibrous filter disc which only allows entry of bacteria-free air. The package is opened by tapping the end 20 until the seal 37 is broken and then by pushing upwardly member 14 until the syringe can be withdrawn together with the closure member which remains seated on the hub 26 to protect the needle until the syringe is to be filled. Modifications include directly sealing as at 114, Fig. 6, the top of the syringe piston 111 to the main sleeve, and providing a longitudinally extended cap 13 so that a filled syringe may be packaged, the closure member 14 in this case being provided ...

Improvements relating to the sterilization of hypodermic syringes

... 894,854. Sterilizing particles and containers therefor. EVERETT & CO. Ltd., S. & R. J. Jan. 29, 1960 [Jan. 30, 1959; Feb. 19, 1959], Nos. 3423/59 and 5780/59. Class 81 (1). [Also in Group XVII] A method of sterilizing an article, e.g. a hypodermic syringe, by means of dry heat is characterized in that in order to prevent the escape of air during heating, and the consequent entry of unsterile air on cooling, the article to be sterilized is enclosed within a cylindrical container which is just large enough to receive the article, the container being closed at one end by a sealed lid and the body of the container having no other opening. As shown, a rigid container intended for the sterilization and subsequent storage of a hypodermic syringe is in the form of a cylindrical can with a lid 4 having a deep flange 5 which in conjunction with a ring of silicone rubber 6 of 0-section located in a groove effects an air-tight seal. A clip 10 engages the bottom 11 and top 12 of the can to counteract ...

DEVICE FOR HANDLING OBJECTS AND MAKING OF AN UNHINDERED FLOW OF A TREATMENT FLUID POSSIBLE

PROCEDURE AND DEVICE FOR THE CONTINUOUS MEASUREMENT, COLLECTION AND REGULATION OF THE SUPPORTING PRESSURE DURING A STEAM STERILIZATION

EINWEG-INJEKTIONSVORRICHTUNG

BEHANDLUNGSUND TRANSPORT CONTAINER

FOR GAS STERILISATION SUITABLE PACKING

INJECTION SYRINGE

PACKING FOR TRANSPORT OF STERILE ARTICLES OR TO STERILIZING ARTICLES

AUFBEWAHRUNGSBEHALTER FUR KANULEN

PROCEDURE FOR THE ASSEMBLY OF A SPRITZE-BEHÄLTER COMBINATION

VORGEFÜLLTE INJECTION PACKING AND BUT PLANNING PROCEDURE FOR DISINFECTING OR STERILIZING.

ANGIOGRAPHI INJECTOR

SYRINGE AND PROTECTOR CAP

Sterile packing and sterilization method using this packing

The packing according to the invention comprises: a container for holding said at least one object to be sterilized, having an inlet opening and a discharge opening via which said at least one object may pass into and out of said container, said container comprising a rigid part which comprises a peripheral wall bored with a multitude of small holes having dimensions smaller than those of the said at least one object, and a non-rigid part in a material porous to the sterilization fluid and non-porous to microbial contamination, this non-rigid part being able to contain said rigid part and to be sealed thereon; and at least one envelope made in a flexible and airtight material, which is vacuum sealing fitted on said container.

Service and Maintenance Station for Handheld Drug Delivery Device

The present invention relates to a service and maintenance station for a handheld drug delivery device of pen-injector type, comprising: 110-. (canceled)11. Service and maintenance station for a handheld drug delivery device of pen-injector type , comprising:a receptacle section to receive at least a portion of the drug delivery device,at least one service module adapted to maintain and/or to restore the operability of the drug delivery device, wherein the at least one service module comprises a cleaning and/or sterilizing module adapted to receive, to clean and/or to sterilize a distal end section of the drug delivery device to be connected with a piercing assembly.121. The service and maintenance station according to claim , wherein the receptacle section comprises at least one fixing means for keeping the drug delivery device in a service position.13. The service and maintenance station according to claim 11 , further comprising a fan and/or a heating module for drying and/or sterilizing the distal end section of the drug delivery device.14. The service and maintenance station according to claim 11 , wherein the at least one service module comprises a sensing arrangement adapted to determine a filling level of a cartridge placed in the drug delivery device and being filled with a medicament to be dispensed by the drug delivery device.15. The service and maintenance station according to claim 11 , wherein the at least one service module comprises a cooling member adapted to refrigerate the receptacle section.16. The service and maintenance station according to claim 11 , further comprising a charging module adapted to be electrically coupled with a re-chargeable battery of the drug delivery device.17. The service and maintenance station according to claim 11 , further comprising a battery module.18. The service and maintenance station according to claim 11 , further comprising an input/output interface for providing device-related information to a user and/or for ...

Method and Apparatus for Delivering a Therapeutic Substance Through an Injection Port

Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.

MEDICAL INJECTION DEVICE HAVING A TELESCOPICALLY MOVABLE SHIELD

The invention relates to a pre-filled injection device for apportioning a plurality of set doses of a liquid drug comprising. The housing of the injection device supports a non-replaceable cartridge containing the liquid drug. The cartridge is e.g. secured in a cartridge-holder being a part of the housing. A needle assembly comprising a needle cannula secured in a hub is slidable mounted to slide into contact with the cartridge. The tip of the needle cannula is covered by a telescopically movable shield movable from an extended position to a retracted position. The telescopically movable shield supports a cleaning chamber containing a cleaning solvent for cleaning at least the distal tip of the needle cannula between subsequent injections. The distal end of the housing supports a removable protective cap and the telescopically movable shield is guided relatively to the housing and coupled to the protective cap to follow movement of the protective cap. 1. A pre-filled injection device for apportioning set doses of a liquid drug comprising:A pen-shaped housing extending in a longitudinal direction and having a needle supporting distal end,A removable protective cap mountable on the housing and covering at least a part of the needle supporting distal end between injections, and which removable protective cap is rotatable relatively to the housing when mounted there upon,A non-replaceable cartridge permanently embedded in the housing of the pre-filled injection device and having an interior containing the liquid drug,A needle assembly comprising a needle cannula secured in a hub which needle cannula has a distal end with a distal tip and a proximal end and wherein the proximal end of the needle cannula is inserted into the cartridge,A telescopically movable shield movable from an extended position covering at least the distal tip of the needle cannula to a retracted position and which telescopically movable shield carries a cleaning chamber containing an amount of the ...

Protection against spill and syringe related contamination

Methods and apparatus for employing an adhesive strap about a medical connection for improving connection integrity for greater safety and reliability and a cross contamination barrier for medical syringes is disclosed. Also, a shielding tube for a medical syringe which acts as a barrier against cross contamination across a syringe plunger is disclosed. The tube comprises a pattern of raised ribs inside to protect against potentially tube tearing edges of an associated plunger rod assembly and to provide a skid resistant surface when disposed about flanges of the syringe. 1. A method for providing a cinch across a first medical friction fit luer-lock connector used in tandem with a second like luer-lock connector whereby likelihood of disengagement of the first luer-lock connector is reduced relative to likelihood of disengagement of the second luer-lock connector to assure a desired disconnection only , said method comprising the steps of:(a) providing a first part comprising the first luer-lock connector;(b) providing a second part comprising a luer-lock connector which is complimentary to said first luer-lock connector to which the first luer-lock connector is tightly affixed by conventional rotation in a predetermined direction;(c) providing an inelastic, elongated planar strap comprising one side having backing material covering an adhesively treated side by which a portion of said backing material is removed to permit said strap to be rotationally affixed to said first part by wrapping said strap rotationally counter to the predetermined direction and by continuing rotation to adhesively affix the strap to the second part;(d) using conventional technique, tightly affixing the first part to the second part;(e) affixing the strap to the first part by removing backing from a portion of the strap and wrapping that portion of the strap counter to direction of rotation by which the first part is affixed to the second part; and(f) removing the remainder of the ...

SYRINGE DEVICE, SYSTEM AND METHOD FOR DELIVERING OZONE GAS

In accordance with at least one exemplary embodiment, a syringe device, method and system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from the barrel of the syringe through the case. Conducting elements can be attached to the case and can breach the case. The conductive elements can be connected to electrodes. The electrodes can be attached to the syringe. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conductive elements from an ozone generator resulting in a corona discharge from at least one electrode. A therapeutic amount of ozone gas can be produced from the oxygen gas and the syringe delivered into the sterile field without compromise. 1. A syringe device , comprising:a syringe having a plunger slidably engaged with a barrel, the barrel and the plunger cooperating to define a gas chamber; a fluid channel penetrates through the opening of the case when the case operatively encloses the syringe, the fluid channel in fluid communication with the gas chamber;', 'wherein the syringe and case are configured to interface with an ozone conversion unit, and the case maintains sterility of the syringe while interfaced with the ozone conversion unit to effectuate a corona discharge and produce an amount of ozone gas from an amount of oxygen gas within the gas chamber., 'a case for providing substantial sterility, the case including an opening and configured to enclose the syringe;'}2. The syringe device of claim 1 , further comprising:a sterility cap having a portion that is configured to be inserted into the opening of the case and allows for the fluid channel to extend through the sterility cap when the case operatively encloses the syringe.3. The syringe device of claim 1 , further ...

AUTOMATIC NEEDLE INSERTION APPARATUS

The present disclosure provides an automatic needle insertion apparatus, including a frame, a bearing device on the frame and configured to bear thereon a body part into which a needle is to be inserted, an acquisition device on the frame and configured to acquire vascular information of the body part, a needle insertion device on the frame and configured to execute a needle insertion operation and a needle withdrawal operation on the body part, and a first control device connected to the needle insertion device and the acquisition device and configured to control an operating state of the needle insertion device in accordance with the vascular information acquired by the acquisition device. 1. An automatic needle insertion apparatus , comprising:a frame;a bearing device on the frame and configured to bear thereon a body part into which a needle is to be inserted;an acquisition device on the frame and configured to acquire vascular information of the body part;a needle insertion device on the frame and configured to execute a needle insertion operation and a needle withdrawal operation on the body part; anda first control device connected to the needle insertion device and the acquisition device and configured to control an operating state of the needle insertion device in accordance with the vascular information acquired by the acquisition device.2. The automatic needle insertion apparatus according to claim 1 , wherein the acquisition device comprises:an ultrasound image processing unit configured to send an ultrasound pulse to the body part, generate first image data in accordance with an ultrasound signal from the body part, and acquire the vascular information of the body part in accordance with the first image data; and/oran infrared scanning unit configured to generate second image data in accordance with an infrared ray radiated by the body part, and acquire the vascular information of the body part in accordance with the second image data.3. The automatic ...

SYRINGE RETAINING MEMBER, SYRINGE PACKAGE BODY, AND METHOD FOR ASSEMBLY OF SYRINGE PACKAGE BODY

A syringe holding member includes: a base plate portion formed in a substantially rectangular flat plate shape including a longitudinal side and a lateral side; a plurality of holding tube portions into which syringes are insertable, wherein the holding tube portions protrude from an upper surface of the base plate portion and define cylindrical holes that penetrate the base plate portion; and a plurality of reinforcement ribs that protrude from the upper surface of the base plate portion and connect the plurality of holding tube portions to one another. Two or more of the reinforcement ribs extend between a predetermined pair of holding tube portions among the plurality of holding tube portions. 1. A syringe holding member comprising:a base plate portion formed in a substantially rectangular flat plate shape including a longitudinal side and a lateral side;a plurality of holding tube portions into which syringes are insertable, wherein the holding tube portions protrude from an upper surface of the base plate portion and define cylindrical holes that penetrate the base plate portion; anda plurality of reinforcement ribs that protrude from the upper surface of the base plate portion and connect the plurality of holding tube portions to one another,wherein two or more of the reinforcement ribs extend between a predetermined pair of holding tube portions among the plurality of holding tube portions.2. The syringe holding member according to claim 1 , wherein:the holding tube portions are regularly arranged at equal intervals on the upper surface of the base plate portion, andtwo or more of the reinforcement ribs extend between each of a plurality of predetermined pairs of holding tube portions among the plurality of holding tube portions.3. The syringe holding member according to claim 1 , wherein:the holding tube portions are arranged in a plurality of rows in each of a first direction parallel to the longitudinal side of the base plate portion and a second direction ...

Medical apparatus and method for sterilizing medical apparatus

According to the invention, there is provided a medical apparatus including: one or more sterile pre-filled syringe; one or more first protective container including the one or more sterile prefilled syringe, wherein the one or more first protective container is impermeable to moisture and/or sterilizing agents; a second protective container including one or more medical components and the one or more first protective container; and a package impermeable to bacteria including the second protective container.

Medicament delivery device comprising a visual indicator

A pharmaceutical delivery device includes a cartridge containing a fluid. The cartridge includes a light pipe section having an input location and a light diffusing section optically coupled to the light pipe. A light source is optically coupled to the cartridge at the input location to the light pipe, such that at least some light from the light source entering at the input location is diffused at the light diffusing section.

System and method for aseptic packaging of a drug delivery device components

A method for sterilizing a drug delivery device may comprise disposing a liquid drug container, a needle conduit and a cap in a sterilization enclosure so that a mouth portion of the liquid drug container is registered with, and spaced apart from, a circumferential lip of the cap; disposing a cover over the liquid drug container, the needle conduit, and the cap, sealing the sterilization enclosure; subjecting the interior of the sterilization enclosure to a sterilization process in which the liquid drug container, the needle conduit, and the cap are exposed to the sterilization fluid and are sterilized; and applying a downward force to the liquid drug container to move the mouth portion into engagement with the circumferential lip of the cap and to snap the cap onto the liquid drug container to seal the cap and needle conduit to the liquid drug container in an assembled configuration.

Devices, systems, and methods of packaging for a pre-filled drug delivery device

A system for sterilizing a drug delivery device includes a drug delivery device having a first self-healing seal configured to seal a fluid reservoir disposed within the drug delivery device. A sealable container is configured to receive the drug delivery device therein. The sealable container has a base portion and a cover portion. The cover portion has a second self-healing seal positioned to align with the first self-healing seal when the drug delivery device is disposed within the sealable container. A fill port includes a fill path, the fill path being configured to pass through the first and second self-healing seals to fluidly couple the fill port to the reservoir of the drug delivery device. Other systems, methods, and devices of sterilization are also disclosed.

Cap for syringe needle and device for dialysis circuit priming

A needle cap and a dialysis circuit priming device with increased safety and convenience in the cleaning and priming of a blood circuit are provided. According to the present invention, a needle cap is provided including two needle connecting parts, and a flow path connecting the two needle connecting parts. A dialysis circuit priming device is also provided including two needles, two needle connecting parts each arranged with the two needles respectively, and a flow path for connecting the two needle connecting parts.

MODULAR DOSING ASSEMBLY OF MEDICAL SUBSTANCES

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient. 1. A syringe for intermixing beneficial substances , comprising:a syringe having at least two entry ports and at least one exit port, the at least two entry ports configured to receive at least two containers.2. The syringe of claim 1 , wherein the at least two entry ports abut the syringe.3. The syringe of claim 1 , wherein the at least two entry ports abut a wall of the syringe.4. The syringe of claim 1 , wherein the at least two entry ports are surface mounted to the syringe.5. The syringe of claim 1 , wherein the at least two entry ports are surface mounted to a wall of the syringe.6. The syringe of claim 1 , wherein the at least two entry ports are flush mounted to the syringe.7. The syringe of claim 1 , wherein the at least two entry ports are flush mounted to a wall of the syringe.8. The syringe of claim 1 , wherein the at least two entry ports are configured to directly receive the at least two containers.9. The syringe of claim 1 , wherein the at least two entry ports are configured to directly receive and engage the at least two containers.10. The syringe of claim 1 , wherein the at least two containers abut the syringe upon engagement to the bag.11. The syringe of claim 1 ...

Modular dosing assembly of medical substances

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient.

Modular dosing assembly of medical substances

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient.

A MEDICAL INJECTION DEVICE WITH A AXIALLY MOVABLE SHIELD

The invention relates to a prefilled injection pen for apportioning multiple set doses of a liquid drug. The injection pen comprises a housing structure with a distal part supporting a needle cannula and which distal part is covered by a protective cap between subsequent injections. Further, an axially movable shield for covering the distal tip of the needle cannula between injections is provided. This axially movable shield is rotatable relatively to the housing structure between a first locked position and a second unlocked positon. In the first position, the axially movable shield is prevented from moving proximally and in the second position the axially movable shield is allowed to move proximally. The removable protective cap is rotatably coupled to the housing structure and further comprises means for engaging the axially movable shield. 1. An injection device for apportioning set doses of a liquid drug comprisinga housing structure supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected,a needle cannula supported by the housing structure and having a proximal end inserted into the interior chamber the cartridge and a distal end with a distal tip, the first position being a position in which the axially movable shield is prevented from moving proximally, and', 'the second position being a position in which the axially movable shield is allowed to move proximally,, 'an axially movable shield for covering the distal tip of the needle cannula between injections, which axially movable shield is rotatable relatively to the housing structure between a first position and a second positon,'}a removable protective cap coupled to the housing structure for covering at least a distal part of the housing structure and the distal tip of the needle cannula, and which removable protective cap is rotatably coupled to the housing structure requiring rotation of the protective cap relatively to the housing structure to allow ...

Cassette assembly for syringe fill system

A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for “push-pull”, “pull-push”, “push-push”, and “pull-pull” modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single-use components of the syringe fill system.

Haptic feedback and audible output syringe

A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for “push-pull”, “pull-push”, “push-push”, and “pull-pull” modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single-use components of the syringe fill system.

SYRINGE BARREL AND PRE-FILLED SYRINGE

A syringe barrel includes: a hollow body portion that is configured such that a gasket is slidably insertable therein. The syringe barrel is made of a resin that has a total light transmittance of 80% or more. A scale is disposed at an inner circumferential surface or an outer circumferential surface of the body portion, the scale being visible from an outside of the syringe barrel and being configured to indicate a liquid amount. The scale is formed by (i) a stepped structure having a step height in a range of 0.001 to 0.15 mm in a radial direction, and/or (ii) an embossment. 1. A syringe barrel comprising:a hollow body portion that is configured such that a gasket is slidably insertable therein;wherein the syringe barrel is made of a resin that has a total light transmittance of 80% or more;wherein a scale is disposed at an inner circumferential surface or an outer circumferential surface of the body portion, the scale being visible from an outside of the syringe barrel and being configured to indicate a liquid amount; andwherein the scale is formed by (i) a stepped structure having a step height in a range of 0.001 to 0.15 mm in a radial direction, and/or (ii) an embossment.2. The syringe barrel according to claim 1 , wherein the stepped structure is disposed at the inner circumferential surface of the body portion.3. The syringe barrel according to claim 1 , wherein the scale has an annular shape that extends in a circumferential direction of the body portion.4. The syringe barrel according to claim 1 , wherein the scale includes a plurality of scale portions located at intervals in the circumferential direction of the body portion.5. The syringe barrel according to claim 1 , wherein the stepped structure comprises a protrusion that protrudes radially from the inner circumferential surface or the outer circumferential surface of the body portion.6. The syringe barrel according to claim 1 , wherein the stepped structure comprises a groove that is recessed ...

SYRINGE BARREL FOR PRE-FILLED SYRINGE, SYRINGE SYSTEM, AND PRE-FILLED SYRINGE

A syringe body for a prefilled syringe includes: a hollow body portion; a proximal-end opening portion provided at a proximal end portion of the body portion; and a distal-end nozzle provided at a distal end portion of the body portion. The body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer. The body portion has a thick body portion accounting for 80% or more of the body portion along an axial direction. A wall thickness of the thick body portion is 2.23 to 2.40 mm. 1. A syringe body for a prefilled syringe , the syringe body comprising:a hollow body portion;a proximal-end opening portion disposed at a proximal end portion of the body portion; anda distal-end nozzle disposed at a distal end portion of the body portion;wherein the body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer;wherein the body portion includes a thick body portion accounting for 80% or more of the body portion along an axial direction; andwherein a wall thickness of the thick body portion is in a range of 2.23 to 2.40 mm.2. The syringe body according to claim 1 , wherein:a nominal volume of the syringe body is in a range of 0.1 to 5 mL.3. The syringe body according to claim 1 , wherein:{'sup': '2', 'an area of an outer circumferential surface of the body portion is in a range of 1300 to 1600 mm.'}4. The syringe body according to claim 2 , wherein:{'sup': '2', 'an area of an outer circumferential surface of the body portion is in a range of 1300 to 1600 mm.'}5. A syringe system for a prefilled syringe claim 2 , the syringe system comprising: a hollow body portion,', 'a proximal-end opening portion disposed at a proximal end portion of the body portion, and', 'a distal-end nozzle disposed at a distal end portion of the body portion', 'wherein the body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer, and', 'wherein a wall thickness of the body portion is a range of 2.23 to 2.40 mm;, 'a syringe body comprisinga gasket that is ...

SYSTEMS AND METHODS FOR DETECTING AND TREATING BACTERIAL BIOFILMS

Impedance is detected between electrodes coupled to an indwelling medical device to monitor bacteria growth and/or formation of a bacterial biofilm in an in vivo environment. When an antimicrobial agent is present in the in vivo environment, the same voltage that enables impedance detection also generates a bioelectric effect, which decreases a size of the bacterial biofilm or inhibits growth of the bacterial biofilm. In some embodiments, the impedance detected between the electrodes can also be used as a feedback mechanism. When detection indicates that a bacterial biofilm has formed, the system can take remedial measures, such as introducing an antimicrobial agent to the in vivo environment and/or delivering a voltage higher than detecting voltage to deliver a greater bioelectric effect. In some embodiments, the electrodes can be formed on a flexible substrate that is mounted on and conforms to a non-flat surface of the indwelling medical device. 1. A method comprising:(a) delivering an antimicrobial agent to an in vivo environment in which an indwelling medical device is disposed;(b) during a first time period, measuring a first impedance value by applying a first voltage between electrodes disposed over a surface of the indwelling medical device; and(c) determining information regarding bacteria growth on the indwelling medical device based on a comparison of the first impedance value with a previously measured impedance value,wherein the application of the first voltage between the electrodes in the presence of the antimicrobial agent generates a bioelectric effect that decreases a size of a biofilm of the bacteria or inhibits growth of the bacterial biofilm.2. The method of claim 1 , further comprising:(d1) comparing the first impedance value to a predetermined range, and applying a second voltage between the electrodes if the comparison indicates that the first impedance value is outside said range,wherein the second voltage is greater than the first voltage ...

Container

A container includes an upper opening portion, a holder, which is placed in the container, for holding at least one medical device, and a gas non-permeable film for sealing the opening portion. The holder includes a basal plate portion having a plate shape, a plurality of tubular portions protruding downwardly from the basal plate portion, a plurality of stays formed around each of the plurality of tubular portions and connecting another of the plurality of tubular portions, and a support rod protruding downwardly from the basal plate portion and having a length longer than the plurality of tubular portions. The support rod is arranged such that a medical device housed in each of the plurality of tubular portions is not adapted to contact a bottom surface of the container, or another holder adjacent to the holder when the holder and the another holder are stacked.

SYSTEMS AND APPROACHES FOR STERILIZING A DRUG DELIVERY DEVICE

An on-body injector system includes a drug container assembly including a container, a seal member, and a sealing interface between the seal member and the container. The container includes an opening and the seal member at least partially covers the opening in the container. A fluid pathway assembly is coupled to the drug container assembly and includes a needle that is movable between a storage position, in which a point of the needle is spaced from the seal member, and a delivery position, in which the point of the needle is disposed at least partially through the seal member. A radiation generator is configured to emit rays of radiation to sterilize and/or disinfect the sealing interface. A barrier is disposed adjacent to the sealing interface and has an opening. At least a portion of the drug container assembly is positioned adjacent to the opening in the barrier. 1. An on-body injector system comprising:a drug container assembly including a container, a seal member, and a sealing interface between the seal member and the container, the container having an opening and the seal member at least partially covering the opening in the container;a fluid pathway assembly coupled to the drug container assembly and including a needle, the needle being movable between a storage position, in which a point of the needle is spaced from the seal member, and a delivery position, in which the point of the needle is disposed at least partially through the seal member;a radiation generator configured to emit rays of radiation to sterilize and/or disinfect the sealing interface;a barrier disposed adjacent to the sealing interface and having an opening; andwherein at least a portion of the drug container assembly is positioned adjacent to the opening in the barrier.2. The on-body injector system of claim 1 , wherein the barrier includes a wall and the opening is formed in the wall.3. The on-body injector system of claim 2 , wherein at least a portion of the container and the ...

ANTIMICROBIAL BARRIER DEVICE

The invention relates to an antimicrobial barrier device and methods of manufacture. The antimicrobial barrier comprises one or more antimicrobial drugs that inhibit biofilm formation and bacterial and/or fungal growth. The antimicrobial barrier is suited for use with insertable devices (e.g., catheters) to reduce the incidence of infection at and around the insertion site. 1. An antimicrobial barrier device comprising:a soft durometer silicone body comprising one or more directly incorporated antimicrobial drugs selected from the group consisting of an antifungal agent and an antibacterial agent, the soft durometer silicone body being substantially resistant to microbial colonization thereon, and havinga) a first surface adapted to conform to a treatment area; andb) a hole extending therethrough, the hole being adapted to receive and seal to an insertable medical device.2. The antimicrobial barrier device of wherein the soft durometer silicone body is about 10 A to about 80 A durometer silicone.3. The antimicrobial barrier device of wherein the soft durometer silicone body is about 10 A to about 50 A durometer silicone.4. The antimicrobial barrier device of wherein the soft durometer silicone body is about 50 A durometer silicone5. The antimicrobial barrier device of wherein the one or more directly incorporated antimicrobial drugs is selected from the group consisting of a rifamycin claim 1 , rifampicin claim 1 , nitrofurantoin claim 1 , triclosan claim 1 , trimethoprim claim 1 , nalidixic acid claim 1 , vancomycin claim 1 , a tetracycline claim 1 , doxycycline claim 1 , minocycline claim 1 , tetracycline claim 1 , an aminoglycoside claim 1 , amikacin claim 1 , gentamicin claim 1 , neomycin claim 1 , tobramycin claim 1 , a fluoroquinolone claim 1 , ciprofloxacin claim 1 , levofloxacin claim 1 , trovafloxacin claim 1 , gemifloxacin claim 1 , gentian violet claim 1 , flucytosine claim 1 , an azole drug claim 1 , fluconazole claim 1 , miconazole claim 1 , ...

DECONTAMINATION DEVICE FOR PHARMACEUTICAL VESSELS

The present invention relates, in some embodiments thereof, to systems, devices and methods for decontaminating a surface of one or more vessels. In some embodiments, the systems and devices of the invention include a housing, and a wiping member disposed within the housing being configured to wipe off the surface of one or more vessels, thereby establishing a contaminant-free fluid passageway between vessels. 1. A method of decontaminating a surface of at least two vessels , the method comprising:providing a decontamination device comprising a housing and a wiping member disposed within the housing configured to move within the housing;providing a first vessel having a surface;providing a second vessel having a surface;connecting the device to the first vessel;connecting the device to the second vessel; andmoving the wiping member within the housing, thus, decontaminating a surface of the first vessel, and decontaminating a surface of the second vessel.2. The method of claim 1 , wherein moving the wiping member across the housing decontaminates a surface of the first vessel and a surface of the second vessel.3. The method of claim 1 , wherein the first vessel is connected to the decontamination device prior to the second vessel being connected to the device.4. The method of claim 1 , wherein the first vessel is connected to the decontamination device after the second vessel is connected to the decontamination device.5. The method of claim 1 , wherein the first vessel is connected to the decontamination device and the second vessel is connected to the decontamination device at about the same time or at the same time.6. The method of claim 2 , wherein the moving of the wiping member across the housing occurs after the first vessel and the second vessel are connected to the device.7. A decontamination system claim 2 , comprising:a device comprising a housing, and a wiping member disposed within the housing, wherein the wiping member is configured to move within the ...

DECONTAMINATION DEVICE FOR PHARMACEUTICAL VESSELS

The present invention relates, in some embodiments thereof, to systems, devices and methods for decontaminating a surface of one or more vessels. In some embodiments, the systems and devices of the invention include a housing, and a wiping member disposed within the housing being configured to wipe off the surface of one or more vessels, thereby establishing a contaminant-free fluid passageway between vessels. 1. A decontamination system , comprising:a device comprising a housing, and a wiping member disposed within the housing, wherein the wiping member is configured to move within the housing; andat least one vessel having a surface,wherein the wiping member decontaminates the surface of the at least one vessel, andwherein the at least one vessel is configured to detach from the device after the surface of the at least one vessel has been decontaminated.2. The system of claim 2 , further comprising an actuator configured to move the wiping member within the housing.3. The device of claim 2 , wherein the actuator is selected from a group consisting of a handle claim 2 , tab claim 2 , a button claim 2 , a touch button claim 2 , a lever claim 2 , a gear claim 2 , a spring claim 2 , a mechanical actuator claim 2 , an electric actuator claim 2 , and combinations thereof.4. The device of claim 2 , wherein the actuator is connected to the wiping member and configured to move the wiping member.5. The device of claim 1 , wherein the vessel includes a fluid claim 1 , wherein the fluid is configured to travel through the device after the surface of the at least one vessel has been decontaminated.6. The device of claim 5 , wherein the system includes a capping or resealing mechanism disposed within the housing that is configured to seal the surface of the at least one vessel.7. A decontamination system claim 5 , comprising:a device comprising a housing, and a wiping member disposed within the housing, wherein the wiping member is configured to move within the housing; andat ...

Intravenous Flushing System

An intravenous flushing system includes an intravenous tube that has an input port. A cleaning unit is provided and the cleaning unit contains a saline solution. The cleaning unit is selectively coupled to the input port. The cleaning unit urges the saline solution through the intravenous tube thereby facilitating the intravenous tube to be cleaned. A sterilizing unit is removably coupled to the cleaning unit. The sterilizing unit is infused with an antiseptic. The sterilizing unit engages the input port. Thus, the antiseptic sterilizes the input port. 1. An intravenous flushing system comprising:an intravenous tube having an input port;a cleaning unit being configured to contain a saline solution, said cleaning unit being selectively coupled to said input port wherein said cleaning unit is configured to urge the saline solution through said intravenous tube thereby facilitating said intravenous tube to be cleaned; anda sterilizing unit being removably coupled to said cleaning unit, said sterilizing unit being infused with an antiseptic, said sterilizing unit engaging said input port wherein said antiseptic is configured to sterilize said input port.2. The system according to claim 1 , wherein said cleaning unit comprises a syringe having a first end claim 1 , a second end and an outer wall extending therebetween claim 1 , each of said first end and said second end being open claim 1 , said syringe being configured to contain the saline solution claim 1 , said second end selectively engaging said input port such that said syringe is in fluid communication with said intravenous tube.3. The system according to claim 2 , further comprising a plunger having a primary end and a secondary end claim 2 , said plunger being slidably positioned in said syringe wherein said plunger is configured to be manipulated claim 2 , said secondary end frictionally engaging said outer wall of said syringe such that said secondary end forms a fluid impermeable seal with said outer wall ...

A Needle Arrangement

The present invention relates to a needle arrangement for an injection device. The needle arrangement is made up from needle cannula which is mounted such that a distal part having a distal tip extends in a distal direction. Further, a telescopically movable shield carrying a cleaning chamber surrounds at least the tip of the needle cannula between injections such that the tip of the needle cannula is maintained inside the cleaning chamber between subsequent injections. The cleaning chamber is at least distally provided with a pierceable septum through which the needle cannula penetrates during injections. For guiding the needle cannula during injections a telescopically movable tube is provided. During injections the distal end of the telescopically movable tube at least partly penetrates the distal septum. 1. A needle arrangement for an injection device comprising:a needle cannula having a lumen and mounted such that a distal part having a distal tip extend in a distal direction,a telescopically shield slidable between a first extended position and a second retracted position and wherein the telescopically shield distally carries a cleaning chamber containing a cleaning solvent for cleaning at least the tip of the needle cannula between subsequent injections and which cleaning chamber at least distally is provided with a pierceable distal septum, wherein the telescopically shield in the first extended position is extended to at least cover the distal tip of the needle cannula and in the second retracted position is retracted to at least expose the tip of the needle cannula,a telescopically movable tube for guiding the needle cannula, the telescopically movable tube having a tube lumen and a distal end wherein the needle cannula is guided inside the tube lumen and wherein the distal end of the telescopically tube at least partly penetrates the distal septum when the telescopically shield is moved from the first extended position to the second retracted position.2. ...

Protective Assembly for a Syringe

The present invention relates to a needle shield assembly for a syringe (), comprising an inner needle shield () which is flexible and designed to enclose a major part of a hollow injection needle () of said syringe; an outer needle shield () which is rigid and designed to enclose a major part of said inner needle shield (), which outer needle shield () is arranged with a number of passages () for allowing sterilizing agents to reach said injection needle () during a sterilization process. The invention is characterised in that said needle shield assembly further comprises a cover element () arranged adjacent said passages () such as to prevent the interior of said injection needle () from being exposed to oxygen via said passages () of said outer needle shield () after said sterilization process. 117-. (canceled)18. A protective assembly for a syringe , the syringe having a distal end and a proximal end interacting with a needle shield assembly comprising:an inner needle shield which is flexible and designed to enclose a major part of a hollow injection needle of said syringe;an outer needle shield which is rigid and designed to enclose a major part of the inner needle shield, which outer needle shield is arranged with a number of passages for allowing sterilizing agents to reach the injection needle during a sterilization process;wherein the needle shield assembly of the protective assembly further comprises a cover element arranged adjacent said passages such as to prevent the interior of said injection needle from being exposed to oxygen via said passages of said outer needle shield after said sterilization process.19. The protective assembly according to claim 18 , further comprises a seal for the distal end of the container.20. The protective assembly of claim 18 , wherein the cover element is made of an oxygen-impermeable material.21. The assembly of claim 18 , wherein the cover element comprises a sleeve arranged to be attached to and cover at least a part ...

A Medical Injection Device having a Telescopically Movable Shield

The invention relates to a pre-filled injection device for apportioning a plurality of set doses of a liquid drug comprising. The housing of the injection device supports a non-replaceable cartridge containing the liquid drug. The cartridge is e.g. secured in a cartridge-holder being a part of the housing. A needle assembly comprising a needle cannula secured in a hub is slidable mounted to slide into contact with the cartridge. The tip of the needle cannula is covered by a telescopically movable shield movable from an extended position to a retracted position. The telescopically movable shield supports a cleaning chamber containing a cleaning solvent for cleaning at least the distal tip of the needle cannula between subsequent injections. The distal end of the housing supports a removable protective cap and the telescopically movable shield is guided relatively to the housing and coupled to the protective cap to follow movement of the protective cap. 1. A pre-filled injection device for apportioning set doses of a liquid drug comprising:A pen-shaped housing extending in a longitudinal direction and having a needle supporting distal end,A removable protective cap mountable on the housing and covering at least a part of the needle supporting distal end between injections, and which removable protective cap is rotatable relatively to the housing when mounted there upon,A non-replaceable cartridge permanently embedded in the housing of the pre-filled injection device and having an interior containing the liquid drug,A needle assembly comprising a needle cannula secured in a hub which needle cannula has a distal end with a distal tip and a proximal end and wherein the proximal end of the needle cannula is inserted into the cartridge,A telescopically movable shield movable from an extended position covering at least the distal tip of the needle cannula to a retracted position and which telescopically movable shield carries a cleaning chamber containing an amount of the ...

CLEANING DEVICE AND METHOD FOR FLUID TRANSFER CONNECTOR

A cleaning device for cleaning an ISO 80369-3 formatted connector that has a lumen. The cleaning device is oriented along a longitudinal axis and has a handle, a plug, and a plurality of brushes. 1. A cleaning device for cleaning an ISO-80369-3 formatted connector comprising a lumen , the cleaning device comprising:a base comprising a gripping portion and a plug portion, the base being oriented along a longitudinal axis, the gripping portion and the plug portion being in a fixed positional relationship with respect to each other along the longitudinal axis, the plug portion being configured for engaging an ISO-80369-3 formatted connector lumen; anda plurality of cleaning brushes each comprising an elongate rod and a circular array of bristles extending therefrom, the plurality of cleaning brushes being in a spaced apart relation from each other, the plurality of cleaning brushes being radially disposed about the base plug portion, the elongate rods being operably supported along an orientation parallel to the longitudinal axis, the elongate rods being laterally offset from the longitudinal axis, the plurality of cleaning brushes being operably rotatable about the longitudinal axis, and the plurality of cleaning brushes being operably rotatable about the ISO-80369-3 formatted connector lumen.2. The cleaning device of claim 1 , wherein the plug portion comprises an elongated guide shaft.3. The cleaning device of claim 1 , wherein the plug portion is configured for sealingly engaging the ISO-80369-3 formatted connector lumen.4. The cleaning device of claim 1 , wherein the ISO-80369-3 formatted connector is a male ENFIT connector.5. The cleaning device of claim 1 , wherein the elongate rods are laterally offset a fixed radial distance from the longitudinal axis.6. The cleaning device of claim 1 , wherein the gripping portion and the plug portion form an integral structure.7. The cleaning device of claim 1 , wherein the plurality of cleaning brushes operably rotate about ...

Sterilization Arrangement for Drug Delivery Device

A drug delivery system for injecting a medicament includes a housing defining a cavity, a container received within the cavity and configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly received within the cavity and configured to drive the stopper within the container, a needle actuator assembly received within the cavity and comprising a needle configured to be placed in fluid communication with the container, the needle moveable from a first position and a second position spaced from the first position, and a sterilizer received within the cavity and configured to sterilize at least one of the container, the drive assembly, and the needle actuator assembly upon activation of the drug delivery system. 1. A drug delivery system for injecting a medicament , the system comprising:a housing defining a cavity;a container received within the cavity and configured to receive a medicament, the container comprising a stopper configured to move within the container;a drive assembly received within the cavity and configured to drive the stopper within the container;a needle actuator assembly received within the cavity and comprising a needle configured to be placed in fluid communication with the container, the needle moveable from a first position and a second position spaced from the first position; anda sterilizer received within the cavity and configured to sterilize at least one of the container, the drive assembly, and the needle actuator assembly upon activation of the drug delivery system.2. The drug delivery system as claimed in claim 1 , wherein the sterilizer comprises at least one light source that radiates ultraviolet light to sterilize at least one of the container claim 1 , the drive assembly claim 1 , and the needle actuator assembly.3. The drug delivery system as claimed in claim 2 , wherein the at least one light source includes at least one light emitting diode (LED) ...

Sterilization Arrangement for Drug Delivery Device

A drug delivery system for injecting a medicament includes a housing defining a cavity, a container received within the cavity and configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly received within the cavity and configured to drive the stopper within the container, a needle actuator assembly received within the cavity and comprising a needle configured to be placed in fluid communication with the container, the needle moveable from a first position and a second position spaced from the first position, and a sterilizer received within the cavity and configured to sterilize at least one of the container, the drive assembly, and the needle actuator assembly upon activation of the drug delivery system. 1. A drug delivery system for injecting a medicament , the system comprising:a housing defining a cavity;a container received within the cavity and configured to receive a medicament, the container comprising a stopper configured to move within the container;a drive assembly received within the cavity and configured to drive the stopper within the container;a needle actuator assembly received within the cavity and comprising a needle configured to be placed in fluid communication with the container, the needle moveable from a first position and a second position spaced from the first position;an actuator configured to initiate a drug delivery process of the drug delivery system; anda sterilizer received within the cavity and configured to sterilize at least one of the container, the drive assembly, and the needle actuator assembly upon initiation of the drug delivery process.2. The drug delivery system of claim 1 , wherein the sterilizer comprises at least one light source that radiates ultraviolet light to sterilize the at least one of the container claim 1 , the drive assembly claim 1 , and the needle actuator assembly.3. The drug delivery system of claim 2 , wherein the at ...

A Medical Injection Device with Telescopically Movable Needle Shield having a Cleaning Chamber for the Needle

The invention relates to a pre-filled injection device for apportioning set dose of a liquid drug. The housing of the pre-filled injection device internally supports a non-replaceable cartridge () having an hollow interior containing a liquid preservative containing drug and externally supporting a removable protective cap (). The piston rod drive system of the injection device comprises a piston rod abutting a plunger provided inside the cartridge. A needle cannula () having a distal part with a distal tip and an opposite proximal part and a lumen there between is insertable into the cartridge. A telescopically movable () shield movable from an extended position covering at least the distal tip of the needle cannula to a retracted position exposing at least the distal tip of the needle cannula is further provided. The telescopically movable shield carries a cleaning chamber () able to contain a quantum of the liquid preservative containing drug for cleaning at least the distal tip of the needle cannula between subsequent injections. The quantum of the liquid preservative containing drug contained in the hollow interior of the cartridge is transferred to the cleaning chamber through the lumen of the needle cannula by moving the cartridge axially in relation to the plunger by use of a transfer assembly. 1. A pre-filled injection device for apportioning set dose of a liquid drug comprising:A housing distally supporting a removable protective cap rotatable mounted on the housing, and which housing proximally supports a piston rod drive system, A non-replaceable cartridge embedded in the housing of the pre-filled injection device and having an interior containing a liquid preservative containing drug, the cartridge having a movable plunger with a proximal surface abutting the piston rod drive system which comprises a piston rod, for moving the movable plunger in the distal direction,A needle cannula having a distal part with a distal tip and an opposite proximal part ...

CLEANING DEVICE AND METHOD FOR USING THE SAME

A cleaning device for cleaning a connector comprising a lumen and an inner threaded surface. The cleaning device includes a cleaning body and a plunger body operably coupled to each other. The cleaning body includes a plurality of elongated cleaning swabs positioned separately apart from and in parallel to each other. The plurality of elongated cleaning swabs are operably rotatable about a connector lumen and in removable engagement with a connector inner threaded surface. The plunger body includes an elongated plug to removably engage the connector lumen. The cleaning body and the plunger body are translatably coupled along a common operational axis. The cleaning body and the plunger body are rotatably coupled with respect to each other about the common operational axis. The cleaning body is an integral structure. 1. A cleaning device for cleaning a connector comprising a lumen and an inner threaded surface , the cleaning device comprising:a cleaning body and a plunger body operably coupled to each other, the cleaning body comprising a plurality of elongated cleaning swabs positioned separately apart from and in parallel to each other, the plurality of elongated cleaning swabs being operably rotatable about a connector lumen and in removable engagement with a connector inner threaded surface, the plunger body comprising an elongated plug to removably engage the connector lumen;wherein, the cleaning body and the plunger body are translatably coupled along a common operational axis, the cleaning body and the plunger body being rotatably coupled with respect to each other about the common operational axis, and wherein the cleaning body is an integral structure.2. The cleaning device of claim 1 , wherein the cleaning body and the plunger body are operably coupled to each other with a locking assembly.3. The cleaning device of claim 2 , wherein the locking assembly comprises a tab engaged with an aperture.4. The cleaning device of claim 3 , wherein the aperture extends ...

PLATE FOR HOLDING DRUG INJECTION DEVICE TUBES

A tray intended to hold injection device tubes includes a collar at each end of a body. In order to carry out operations of preparing the injection device tubes, the tray includes bores and each bore is configured to receive a body of an injection device tube. Also, each bore of the tray includes a holding portion for holding the upper collar of the tube and the holding portion extends laterally from an introduction portion enabling the passage of the lower collar. 1. A tray for holding injection device tubes including a collar at each end of a body , the tray comprising bores that receive the body of the tube , wherein each bore includes a holding portion configured to hold an upper collar of the tube , the holding portion extending laterally from an introduction portion configured to enable passage of a lower collar of the tube.2. The tray according to claim 1 , wherein each bore includes claim 1 , on a front side claim 1 , the holding portion having a circular-arc-shaped contour to adjustably receive the body of the tube.3. The tray according to claim 2 , wherein the holding portion extends rearwardly from the introduction portion claim 2 , the introduction portion including a circular-arc-shaped contour configured to enable the passage of the lower collar of the tube.4. The tray according to claim 2 , characterized in that the holding portion includes a vertical wall.5. The tray according to further comprising elastic elements disposed between the holding portion and the introduction portion.6. The tray according to claim 5 , wherein the elastic elements form tabs claim 5 , each tab including a boss separating the holding portion from the introduction portion.7. The tray according to claim 1 , wherein the tray includes a plastic material comprising liquid crystal polymers claim 1 , implemented by injection. This application is a continuation of International Application No. PCT/FR2018/051343, filed on Jun. 8, 2018, which claims priority to and the benefit of FR ...

Medicant Injection Device

A medicant injection device includes a compressible body, a tip, and an outer luer body. The compressible body has a proximal end, a distal end, and a plurality of bellows, and defines an inner cavity for holding a liquid medicant. The tip is positioned at the proximal end of the compressible body. The outer luer body includes internal threads, and is positioned over and engaged with the tip to form a first fitting therewith. The first fitting is configured to be connected with a second fitting. A medicant injection device includes a compressible body having first and second arms, a receptacle interconnected with the compressible body and defining an inner cavity, and a first fitting configured to engage a second fitting. The compressible body is configured to be compressed by forcing the distal end of the first and second arm toward each other. 118-. (canceled)19. A medicant injection device , comprising:a compressible body including a first arm having a proximal end and a distal end,and a second arm having a proximal end and a distal end, wherein the first arm and the second arm are connected at their respective proximal end forming a proximal base;a receptacle interconnected with the compressible body and defining an inner cavity for holding a liquid medicant; anda first fitting positioned at the proximal base and configured to engage a second fitting,wherein the compressible body is configured to be compressed by forcing the distal end of the first arm and the distal end of the second arm toward each other such that the liquid medicant contained in the receptacle is ejected from the first fitting when the compressible body is compressed.20. The medicant injection device of claim 19 , wherein the receptacle comprises a bag claim 19 , andwherein the first fitting is a first luer fitting.21. The medicant injection device of claim 20 , wherein the receptacle comprises one of polyethylene terephthalate claim 20 , polyethylene claim 20 , foil claim 20 , or linear low ...

METHOD AND APPARATUS FOR DELIVERING A THERAPEUTIC SUBSTANCE THROUGH AN INJECTION PORT

Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and aasures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed. 1. A vial adapter for use with an injection port adapter , comprising:a disc with a bottom surface and a top surface;a plurality of flexible fingers extending from the bottom surface of the disc, the plurality of flexible fingers having a circumferentially extending retention flange formed on an inner surface of the fingers, the retention flange has a symmetrical cross-sectional shape in circumference, wherein the flexible fingers are configured to fit over a neck of a vial, and the flexible fingers allow the retention flange to pass over a crimp ring on the neck of the vial;a cylinder extending from the top surface of the disc, the cylinder having an outside diameter that corresponds to the inner diameter of an injection port adapter;a septum covering an opening at a top edge of the cylinder to form a cavity within the cylinder; anda cannula that extends through the disc into the cavity in the cylinder.2. A vial adapter according to claim 1 , wherein the septum is flush with the top edge of the ...

SYRINGE

The invention provides a syringe for use in an ophthalmic injection. The syringe comprises a body, a stopper and a plunger. The body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet. The plunger comprises a plunger contact surface at a first end and a rod extends between the plunger contact surface and a rear portion. The plunger contact surface is arranged to contact the stopper but not couple thereto, such that the plunger can be used to force the stopper towards the outlet end of the body, reducing the volume of the variable volume chamber, but not to move the stopper away from the outlet end. 148-. (canceled)49. A method for terminal sterilization of a pre-filled , small volume syringe , the method comprising: a body; a stopper; and', 'a plunger; and', 'about 0.05 ml to 0.5 ml of an injectable ophthalmic medicament which comprises a biologic active ingredient;', 'wherein the body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet,', 'wherein the plunger comprises a plunger contact surface at a first end and a rod extending between the plunger contact surface and a rear portion, the plunger contact surface is arranged to contact the stopper but does not couple thereto, such that the plunger can be used to force the stopper towards the outlet end of the body, thereby reducing the volume of the variable volume chamber, but does not to move the stopper away from the outlet end,', 'wherein the stopper comprises at least a front circumferential rib and a rear circumferential rib which are separated in a direction along the longitudinal axis of the body by at least 3 mm and which define a sterility zone,', 'wherein the rod includes ...

Pen-Type Drug Injection Device having Multiple-Use Needle Module with Needle Cleaning Reservoir

Disclosed is a medical injection device () comprising a needle assembly () having a cannula () and a telescopic shield () for covering the distal tip () in a no use situation. The telescopic shield further carries a cleaning reservoir () for cleaning the needle cannula between two subsequent injections. The cleaning reservoir is provided with an opening () connecting to an overflow reservoir () such that the cleaning liquid contained in the cleaning reservoir can retract and expand upon temperature changes and does not enter the needle lumen instead. In one example, the overflow reservoir is formed as a channel (). 1. A medical injection device for apportioning set doses of a liquid drug , comprisinga housing supporting a cartridge containing the liquid drug,a needle cannula having a distal part with a distal tip and an opposite proximal part and a longitudinal lumen there between, the needle cannula being mounted relatively to the housing such that the distal part extend in a distal direction and the proximal part extend in a proximal direction and into the cartridge,a telescopically movable shield which is telescopically movable in relation to the housing and urged in the distal direction by a spring means operable between the telescopically movable shield and the housing, and wherein the telescopically movable shield carries a first cleaning reservoir containing a liquid cleaning solvent for cleaning at least the distal tip of the needle cannula between subsequent injections,wherein the first cleaning reservoir distally is sealed by a distal seal and proximally by a proximal seal longitudinal spaced from each other to define a volume containing the cleaning solvent and wherein the first cleaning reservoir further is provided with an opening connecting the first cleaning reservoir with a second overflow reservoir to accommodate a volume expansion of the liquid cleaning solvent contained in the first cleaning reservoir.2. A medical device according to claim 1 , ...

LOCAL DISINFECTION FOR PREFILLED DRUG DELIVERY SYSTEM

A therapeutic substance delivery device is provided for delivering therapeutic substance to the subject. A sterile fluid path includes a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path. The delivery device engages with a prefilled therapeutic substance reservoir, such that a disinfection chamber is defined between the sterile fluid path and the reservoir. The needle penetrates the disinfection chamber and subsequently the reservoir when the therapeutic substance delivery device and the reservoir are engaged with one another. A disinfection assembly is disposed within the delivery device and configured to disinfect the disinfection chamber prior to the needle penetrating the disinfection chamber. Control circuitry activates the disinfection assembly, terminates the activation of the disinfection assembly, and subsequently drives the needle to penetrate the disinfection chamber and subsequently the reservoir. 1. Apparatus for delivering a therapeutic substance to a subject , the apparatus comprising: (a) comprising a sterile fluid path for delivering the therapeutic substance to the subject, the sterile fluid path comprising a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path, and', '(b) configured to engage with a prefilled therapeutic substance reservoir, such that when the therapeutic substance delivery device and the reservoir are engaged with one another a disinfection chamber is defined between the sterile fluid path and the reservoir, the needle being configured to penetrate the disinfection chamber and subsequently the reservoir when the therapeutic substance delivery device and the reservoir are engaged with one another, such that fluid communication is established between the reservoir and the sterile fluid path;, 'a therapeutic substance delivery devicea disinfection assembly disposed within the therapeutic ...

Systems and approaches for sterilizing a drug delivery device

A shielding member for use in sterilizing drug container assemblies includes a housing. The housing includes a first shielding portion and a second shielding portion. The first shielding portion includes a first and second surfaces and a plurality of first bore portions extending between. The second shielding portion having a first and second surfaces and a plurality of second bore portions corresponding to and aligned with the plurality of first bore portions. The first and second bore portions cooperate to form a plurality of receptacles including a plurality of openings in the first surface of the first shielding portion of the housing. The receptacles are sized and configured to receive drug container assemblies, each comprising a container with a container contact region and a seal member disposed adjacent the container contact region to seal the contents of the container at a sealing interface, such that each drug container assembly is exposed out of the housing through one of the openings.

PORTABLE SELF SANITIZING MICRONEEDLE DEVICE

A portable, self-sanitizing microneedle device similar in size and shape to a pen, or marker that can be held and manipulated by a human hand. The microneedle device is comprised of a main body with a handle attached to a circular base support structure, a second circular platform structure having screw threads to connect with screw threads on the inside of a substantially conical-shaped cap with a hexagonal base that holds a disinfecting solution, and a third circular platform structure comprising the microneedle support structure covered with a substrate holding a plurality of microneedles. The cap is sealingly and removably attached to the base support structure over the microneedle array using a plurality of sealing surfaces within the cap and on the support structures to create a tight seal that prevents the leakage of the disinfecting solution, and keeps the microneedles sanitized for use at all times, even when traveling. 1. A portable , self-sanitizing microneedle device comprising:a main body structure;said main body structure comprising, a substantially circular base support structure connected to a broad top end of a handle structure;said handle structure having a tapered distal end;wherein said circular base support structure having two additional tiers of circular platform structures decreasing in circumference from said base support structure to a top third platform structure;wherein said top third platform structure comprises a microneedle holding structure;said microneedle holding structure covered with a substantially planar substrate;wherein said substantially planar substrate holding a plurality of microneedles;said plurality of microneedles each having a broad base end embedded in said substrate and a tapered sharp end projecting upward from said substrate;said plurality of microneedles arranged in concentric circles on said substrate;a second platform structure between said base support structure and said third platform structure comprising said ...

NEEDLELESS CONNECTOR AND ACCESS PORT DISINFECTION CLEANER AND ANTIMICROBIAL PROTECTION CAP

A protective cap having a first cap and a second cap that are removably coupled together for use in short-term and long-term antimicrobial treatment of needleless connectors and access ports of an infusion system. The instant invention further provides a protective cap having a first cap and a second cap that each coupled to a different surface of a component of an infusion system, such as a syringe. The instant invention further provides a strip containing a plurality of disposable protective caps. 1. A device for antiseptically maintaining a patient fluid line access valve , the device comprising:a first cap having a first end and a second end, the first end comprising a first opening having a first pad disposed therein, and the second end having a coupling feature, the first pad having a central, cylindrical cutout that compresses to provide a central cavity within the first pad when a device is inserted into the first opening; anda second cap having a distal end and a proximal end, the distal end comprising a second opening having a second pad disposed therein, the distal end further comprising a compatible coupling feature for receiving the coupling feature of the first cap.2. The device of claim 1 , further comprising a removable lid covering the first opening.3. The device of claim 2 , wherein the removable lid comprises at least one of a foil lidding material and a polymer lidding material.4. The device of claim 1 , wherein the first cap further comprises a first cavity claim 1 , the first pad being disposed within the first cavity and the second cap further comprises a second cavity claim 1 , the second pad being disposed within the second cavity.5. The device of claim 4 , wherein the first and second cavities are configured to receive an access portion of a patient fluid line access valve.6. The device of claim 1 , wherein the compatible coupling feature comprises a set of threads that is further configured to receive a compatible set of threads on an ...

CONNECTION SYSTEM AND ACTIVE STERILIZER FOR A DRUG DELIVERY DEVICE

A method and system for creating an aseptic connection is disclosed. The method includes arranging a heating element between a first outer sealing surface and a second outer sealing surface such that the heating element is in contact with the first outer sealing surface and the second outer sealing surface. The method further includes applying opposing forces to the first and second outer sealing surfaces such that the first and second outer sealing surfaces are biased towards each other and heating the heating element to sterilize the first outer sealing surface and second outer sealing surface. The method also includes removing the heating element from between the first seal and second seal while continuing to apply the opposing forces to the first and second outer sealing surfaces such that the aseptic connection is simultaneously formed between the first and second outer sealing surfaces. 1. A method for creating an aseptic connection , the method comprising:providing a first body defining an opening, wherein a first seal seals the opening of the first body and the first seal defines a first outer sealing surface;providing a second body defining an opening, wherein a second seal seals the opening of the second body and the second seal defines a second outer sealing surface;arranging the first outer sealing surface in an opposing relationship with the second outer sealing surface;arranging a heating element between the first outer sealing surface and the second outer sealing surface such that the heating element is in contact with the first outer sealing surface and the second outer sealing surface;applying opposing forces to the first and second outer sealing surfaces such that the first and second outer sealing surfaces are biased towards each other;heating the heating element to a predetermined temperature for a predetermined period of time to sterilize the first outer sealing surface and second outer sealing surface; andremoving the heating element from ...

Method of coating a transdermal catheter with an antimicrobial agent

Systems, methods, and articles for providing an antimicrobial composition to the proximal elements of a trans-dermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, an antimicrobial composition on surface a cap element transfers antimicrobial to the proximal end of the transdermal catheter. The system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial.

NEEDLELESS CONNECTOR WITH ANTIMICROBIAL PROPERTIES

A needleless connector and methods for preventing microbial ingress in medical device connections are disclosed. Various examples provide a needleless connector including a male luer having a recessed distal tip surface containing a water-soluble antimicrobial composition. Further examples include a trap for retaining antimicrobial composition. As the needleless connector is inserted into a female connector, a tapered surface distal edge acts to push microorganisms, while the distal tip surface is configured to leave microorganisms undisturbed. After insertion of the needleless connector, microorganisms present on the female luer surface are biased to reside in the recess region. The recess, trap, and antimicrobial composition are configured to facilitate a long-lasting supply of antimicrobial solution within the fluid-filled recess, at the same time confining the antimicrobial solution inside the recess. This produces a high concentration of antimicrobial solution for an extended time, killing microbes, stopping microbial ingress, and preventing infections in patients. 1. A needleless connector comprising:a male connector having a male tapered surface, the male connector further including:i) a distal tip having a distal end;ii) the distal tip having a recess surface proximal to the distal end, wherein the recess surface is radially inward of a line of taper extending along, and distal of, the male tapered surface at a first taper angle relative to a central longitudinal axis of the male connector; andiii) a water-soluble antimicrobial composition positioned on the recess surface.2. The needleless connector of claim 1 , the male connector further comprising a tapered surface distal edge proximal to the distal tip of the male connector claim 1 , the tapered surface distal edge being at a distalmost end of the male tapered surface.3. The needleless connector of claim 2 , wherein the tapered surface distal edge is proximal to at least part of a recess defined by the ...

DISINFECTING CAPPING DEVICE FOR SHARP MEDICAL OBJECTS

A disinfecting capping device for a sharp medical object, such as a medical needle, is provided. The device includes a container comprising a bottom, an open end opposite to the bottom, and a side disposed between the open end and the bottom of the container. The device further includes a first disinfecting member disposed on the internal surface of the side of the container between the open end and the bottom thereof so as to form a cavity for receiving the sharp medical object through the open end of the container. 1. A disinfecting capping device for a sharp medical object , comprising:a container comprising a bottom, an open end opposite to the bottom, and a side disposed between the open end and the bottom of the container, anda first disinfecting member disposed on the internal surface of the side of the container between the open end and the bottom thereof so as to form a cavity for receiving the sharp medical object through the open end of the container,wherein the cavity extends continuously from the open end of the container towards the bottom thereof.2. The disinfecting capping device of claim 1 , wherein the first disinfecting member is further disposed on the internal surface of the bottom of the container.3. The disinfecting capping device of claim 2 , wherein the cavity extends continuously to the bottom of the container.4. The disinfecting capping device of claim 1 , wherein the open end of the container comprises a funnel having a proximal end and a distal end so as to guide the sharp medical object through the distal end inside the cavity of the first disinfecting member.5. The disinfecting capping device of claim 1 , wherein a diameter of the cavity is equal to or less than an external diameter of the sharp medical object.6. The disinfecting capping device of claim 1 , wherein the disinfecting capping device further comprises a first chamber formed by the first disinfecting member claim 1 , the bottom of the container claim 1 , and optionally ...

Deflectable plunger head

The present invention provides a plunger head designed to absorb the increased pressure applied against it during heat sterilization to thereby minimize or prevent plunger head movement during autoclaving. The present invention provides the plunger head as part of a syringe or as part of a kit including a syringe, a plunger rod, and optionally, a pharmaceutical product fluid such as a contrast media. Some pharmaceutically-tolerable gas may be provided in the syringe with the product fluid.

Injection systems and methods

Injection systems and methods of using the same are described herein. Each injection system may include one, two, or more needles, with each needle being configured to move needle between an injection position and a retracted position to deliver an inoculant. The injection needles may rotate about a carriage axis that extends through the injection axis along which each needle moves when moving between their injection and retracted positions. The injection needles in systems that include two or more injection needles may be advanced from the retracted position to the injection position at the same or different times.

Antimicrobial cap for luer connector

A male luer cap comprising a male luer, the male luer having a tapered sealing surface configured to mate with a female tapered surface of a female luer connector to form a substantially fluid-tight seal; a distal tip having a recess defined by a recess surface that is distal to the tapered sealing surface; and a water-soluble antimicrobial composition disposed on the recess surface; wherein the male luer is configured such that, when the male cap is mated with a female connector to form a substantially fluid-tight seal, a cavity is formed between the female tapered surface and the recess surface.

Syringe with energy delivery component and method of use

A syringe having an energy source disposed therein is disclosed. The syringe is capable of both the delivery and/or aspiration of materials as well as the delivery of an effective amount of various types of energy to a target to produce a desired result. A method utilizing the syringe to administer materials and to deliver energy to the material is also disclosed.

Drug delivery systems with sealed and sterile fluid paths and methods of providing the same

The present disclosure relates generally to the field of drug delivery. In particular, the present disclosure relates to a drug delivery system that includes a sealed and sterile fluid path attached to a drug-loaded container. The disclosure further relates to methods for sterilizing a portion of the drug delivery system without exposing the drug-loaded container to harmful sterilization parameters.

OUTER CYLINDER FOR PREFILLED SYRINGE, PIERCING TOOL FOR PREFILLED SYRINGE, PREFILLED SYRINGE, AND PACKAGING BODY FOR PACKAGING OUTER CYLINDER FOR PREFILLED SYRINGE

An outer cylinder for a prefilled syringe has an outer cylinder body with a distal part having an opening and an outer cylinder closure member which seals the opening, accommodates a sealing member through which a needle portion of a hollow needle is penetrable, and is mounted on the distal part of the outer cylinder body. The outer cylinder closure member has a piercing member mounting portion on which the piercing member is mountable and a regulation portion which regulates separation and rotation of the outer cylinder closure member. The outer cylinder closure member further includes a portion which engages the piercing member side engaging portion when the outer cylinder is pressed into the piercing member and which regulates the separation of the piercing member from the outer cylinder closure member, after the outer cylinder closure member side engaging portion engages the piercing member side engaging portion. 1. An outer cylinder for a prefilled syringe comprising , an outer cylinder closure member is mounted on said distal part of said outer cylinder body,', 'wherein said outer cylinder can be mounted a piercing member which includes a piercing member body and a hollow needle mounted to said piercing member body,', 'wherein said outer cylinder closure member accommodates a sealing member which seals said opening of said distal part of said outer cylinder body and is penetrable by said hollow needle of said piercing member,', 'wherein said outer cylinder closure member has a piercing member mounting portion is mountable to said piercing member,', 'wherein said outer cylinder has a regulation portion which regulates separation and rotation of said outer cylinder closure member mounted on said outer cylinder body; and', 'wherein said piercing member mounting portion of said outer cylinder closure member engages said piercing member when said outer cylinder is pressed into said piercing member from a side of said outer cylinder closure member, and said piercing ...

MEDICAL DEVICE PACKAGE

A medical device package includes a medical device including a first end surface and a second end surface; and a medical device storage container configured to store the medical device, the medical device storage container including a container main body and a holding unit located in the storage space, and configured to hold the medical device such that the first end surface faces upward; and a sheet-like sealing member adapted to be glued to the container main body to seal an opening of the container main body. A surface of the sealing member that faces the container main body includes an adhesive applied area on which an adhesive is applied and an adhesive non-applied area on which the adhesive is not applied, the adhesive non-applied area being an area facing at least the first end surface of the medical device held by the holding unit. 1. A drug solution container package comprising: a first end portion,', 'a second end portion opposite to the first end portion and,', 'a main body portion that is disposed between the first end portion and second end portion,', 'wherein the first end portion includes a filling opening and a first end surface that surrounds the filling opening, and', 'wherein the main body portion has a chamber therein configured to be filled with a drug solution via the filling opening; and, 'a plurality of drug solution containers, each including [ a peripheral wall portion having an upper end portion and a lower end portion,', 'a bottom that is continuous with the lower end portion and surrounded by the lower end portion,', 'an opening surrounded by the upper end portion,', 'a flange portion that is continuous with the upper end portion and surrounds the upper end portion, and', 'a storage space formed inside the peripheral wall portion and the bottom,, 'a container main body including, 'a holding portion located in the storage space, the holding portion holding the plurality of drug solution containers such that each of the first end surfaces ...

SYRINGE

The invention provides a syringe for use in an ophthalmic injection. The syringe comprises a body, a stopper and a plunger. The body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet. The plunger comprises a plunger contact surface at a first end and a rod extends between the plunger contact surface and a rear portion. The plunger contact surface is arranged to contact the stopper but not couple thereto, such that the plunger can be used to force the stopper towards the outlet end of the body, reducing the volume of the variable volume chamber, but not to move the stopper away from the outlet end. 117.-. (canceled)18. A syringe , comprising a body , a stopper , and a plunger , wherein the body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet , wherein the plunger comprises a plunger contact surface at a first end and a rod extending between the plunger contact surface and a rear portion , the plunger contact surface is arranged to contact the stopper but does not couple thereto , such that the plunger can be used to force the stopper towards the outlet end of the body , thereby reducing the volume of the variable volume chamber , but does not to move the stopper away from the outlet end , whereby the syringe is suitable for ophthalmic injection , wherein the variable volume chamber is filled with 10 mg/ml solution of ranibizumab , and the dosage volume is 0.05 ml.19. The syringe according to claim 18 , wherein the stopper provides a sealing function by defining the rear of the variable volume chamber with a fluid tight seal claim 18 , which also provides a sterility seal.20. The syringe according to claim 18 , wherein the plunger ...

Pre-Filled Disposable Injection Device

The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device () is made from a housing () containing a non-exchangeable cartridge () for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device () carries the dose setting button () and the distal end carries the needle cannula () having a lumen () through which the settable dose is expelled. The distal end () of the needle cannula () is covered by a telescopic needle covering shield () which shield () can operate between a first position covering the tip () of the needle cannula () and a second retracted position allowing an injection to be performed. The shield () carries a cleaner () which cleans at least the tip () of the needle cannula () between successive injections such that the prefilled injection device can be used without changing the needle cannula () during its life cycle. 2. A pre-filled disposable injection device according to claim 1 , which further comprises a valve which is configured to prevent flow passage through the lumen of the needle cannula when the needle shield is in its first position.5. A pre-filled disposable injection device according to claim 3 , wherein the needle cannula is secured to an axial movable hub.6. A pre-filled disposable injection device according to claim 1 , wherein the shield is locked by a locking mechanism preventing the shield from moving from the first position to the second retracted position unless a dose has been dialled. This application is a Divisional of U.S. application Ser. No. 14/437,389, filed Apr. 21, 2015, which is a 35 U.S.C. § 371 National Stage application of International Application PCT/EP2013/072064 (published as WO 2014/064100), filed Oct. 22, 2013, which claims priority to European Patent Application 12189993.4, filed Oct. 25, 2012; this application claims priority under 35 U.S.C. § 119 to U.S. ...

Packaging container for antimicrobial caps

Systems, methods, and articles for providing an antimicrobial composition to the proximal elements of a trans-dermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, an antimicrobial composition on surface a cap element transfers antimicrobial to the proximal end of the transdermal catheter. The system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial.

Device For Injecting A Pharmaceutical Liquid, Configured To Be Pre-filled

An injection device which is configured to be pre-filled, including a vessel for storing the liquid, having two opposing ends, each provided with an opening, referred to as proximal end and distal end, and arranged to receive a sliding piston in order to exert pressure on the liquid. The vessel includes a wall including at least two vertically adjacent layers, each including vertically adjacent plastic material, the first and second layers having different gas permeability. 1. A device for injecting pharmaceutical liquid , configured to be prefilled , comprising a liquid storage reservoir that has two opposite ends , each provided with an orifice , and referred to as a proximal end and a distal end , and the reservoir being arranged in order to receive a slidable plunger for exerting a pressure on the liquid , characterized in that the reservoir has a wall that comprises at least two superposed layers , each comprising a plastic material , being referred to as a first layer and a second layer , and having a different permeability to gases , the first layer or the second layer being in the form of a film that is overmolded by the other layer.2. The device according to claim 1 , wherein the second layer forms a barrier against gases claim 1 , its oxygen permeability being less than 5 cm/(m*day*bar) at 20° C. and at a relative humidity ratio of 65%.3. The device according to claim 1 , wherein the second layer forms a barrier against gases and comprises a material selected from ethylene/vinyl alcohol copolymer (EVOH) claim 1 , polyester or co-polyester claim 1 , polyamide or co-polyamide claim 1 , or silicon oxide (SiOx).4. The device according to claim 1 , wherein the first layer forms a barrier against water and comprises a cycloolefin polymer.5. The device according to claim 1 , wherein the second layer is on the outer side with respect to the first layer claim 1 , the first layer forming a barrier against water and the second layer forming a barrier against gases.6. ...

CLEANING DEVICE AND METHOD FOR FLUID TRANSFER CONNECTOR

A cleaning swab device and method for cleaning a fluid coupling or connector. The device includes a generally elongate cylindrical tubular swab body, and a channel formed at an end thereof to define at least one cleaning finger for insertion into a housing and/or port of the connector to remove residual fluids, clean and disinfect the connector. The cleaning device optionally further includes a guide stem or plunger configured to extend through the tubular body of the swab, having a plug at one end for sealing debris out of a lumen of the connector during cleaning. 1. A cleaning device for cleaning a connector , the connector comprising a stem and a lumen extending therethrough , the cleaning device comprising:a handle defining a longitudinal central axis;at least one brush mounted to the handle; anda plunger coupled to the handle and generally extending along the longitudinal central axis.2. The cleaning device of claim 1 , wherein the at least one brush is positioned generally parallel to and laterally offset from the longitudinal central axis.3. The cleaning device of claim 1 , wherein an end of the plunger is configured for projecting beyond an end of the handle for engagement with the stem of the connector.4. The cleaning device of claim 3 , wherein the plunger is configured for sealing engagement with the lumen of the stem.5. The cleaning device of claim 1 , wherein the connector further comprises an outer housing surrounding the stem and a space defined between the stem and outer housing claim 1 , and wherein with the plunger sealingly engaged with the lumen the at least one brush can occupy at least a portion of the space to clean the space.6. The cleaning device of claim 1 , wherein the plunger is sized and shaped for sealing engagement with a lumen of an ISO 80369-3 formatted connector.7. The cleaning device of claim 6 , wherein the ISO 80369-3 formatted connector comprises a male ENFit connector.8. The cleaning device of claim 1 , further comprising at ...

Systems and approaches for sterilizing a drug delivery device

A shielding member for use in sterilizing drug container assemblies includes a housing. The housing includes a first shielding portion and a second shielding portion. The first shielding portion includes a first and second surfaces and a plurality of first bore portions extending between. The second shielding portion having a first and second surfaces and a plurality of second bore portions corresponding to and aligned with the plurality of first bore portions. The first and second bore portions cooperate to form a plurality of receptacles including a plurality of openings in the first surface of the first shielding portion of the housing. The receptacles are sized and configured to receive drug container assemblies, each comprising a container with a container contact region and a seal member disposed adjacent the container contact region to seal the contents of the container at a sealing interface, such that each drug container assembly is exposed out of the housing through one of the openings.

A Torsion Spring Driven Injection Device

The invention relates to a torsion spring driven injection device for apportioning individually set doses of a liquid drug. The injection device has a needle cannula () for multiple uses and a cleaning chamber () for cleaning the tip of the needle cannula between subsequent injections. The cleaning chamber is filled with preservative containing liquid drug directly from the cartridge () in a filling sequence which is executed when the user initiates first use of the injection device. The sequence comprises the step of securing the piston rod guide in an inrotatable position and thereafter moving the cartridge in a proximal direction. Such axial movement of the cartridge without a similar movement of the plunger automatically pumps liquid drug from the cartridge and into the cleaning chamber via the lumen of the needle cannula. 1. A torsion spring driven injection device for apportioning multiple doses of a liquid drug , comprising:a housing storing a cartridge containing the liquid drug,a needle cannula connectable with the interior of the cartridge and having a distal tip needle shielded by a movable needle shield carrying a cleaning chamber for cleaning the distal tip of the needle cannula between subsequent injections,a piston rod having an outer surface with a thread and a not-circular cross-section,a rotatable piston rod guide mating the not circular cross-section of the piston rod or having an inner thread mating the outer thread of the piston rod, andoperationally provided in the housing; an internal thread mating the outer thread of the piston rod or a cross-section mating the not circular cross-section of the piston rod such that the piston rod is moved forward in relation to the housing when the piston rod guide are rotated relatively to the housing,a drive tube which is rotatable by a torsion spring operational positioned between the housing and the drive tube,wherein the piston rod guide is axially movable between;a first position in which the piston rod ...

MEDICAL APPARATUS AND METHOD FOR STERILIZING MEDICAL APPARATUS

According to the invention, there is provided a medical apparatus comprising: one or more sterile pre-filled syringe; one or more first protective container comprising the one or more sterile pre-filled syringe, wherein the one or more first protective container is impermeable to moisture and/or sterilizing agents; a second protective container comprising one or more medical components and the one or more first protective container; and a package impermeable to bacteria comprising the second protective container. 1. A method for providing a medical apparatus , the method comprising:i. providing one or more pre-filled syringe contained within one or more first protective container, wherein the one or more first protective container is impermeable to moisture and/or sterilizing agents;ii. providing a second protective container comprising one or more medical components and the one or more first protective container containing the one or more pre-filled syringe; andiii. packaging the second protective container within a package impermeable to bacteria.2. The method of claim 1 , wherein the sterilizing agents are chosen from one or more of ethylene oxide claim 1 , ozone claim 1 , chlorine claim 1 , chlorine dioxide claim 1 , hydrogen peroxide claim 1 , peracetic acid claim 1 , and/or nitrogen dioxide.3. The method of claim 1 , further comprising sterilizing the second protective container.4. The method of claim 1 , further comprising sterilizing the package impermeable to bacteria.5. The method of claim 1 , further comprising sterilizing the one or more pre-filled syringe.6. The method of claim 1 , further comprising sterilizing the one or more first protective container.7. The method of claim 1 , further comprising sterilizing the second protective container by exposing the second protective container to one or more chemical sterilizing agents selected from one or more of ethylene oxide claim 1 , ozone claim 1 , chlorine claim 1 , chlorine dioxide claim 1 , hydrogen ...

SYRINGE

The invention provides a syringe for use in an ophthalmic injection. The syringe comprises a body, a stopper and a plunger. The body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet. The plunger comprises a plunger contact surface at a first end and a rod extends between the plunger contact surface and a rear portion. The plunger contact surface is arranged to contact the stopper but not couple thereto, such that the plunger can be used to force the stopper towards the outlet end of the body, reducing the volume of the variable volume chamber, but not to move the stopper away from the outlet end. 117-. (canceled)18. A syringe , comprising a body , a stopper , and a plunger , wherein the body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet , wherein the plunger comprises a plunger contact surface at a first end and a rod extending between the plunger contact surface and a rear portion , the plunger contact surface is arranged to contact the stopper but does not couple thereto , such that the plunger can be used to force the stopper towards the outlet end of the body , thereby reducing the volume of the variable volume chamber , but does not to move the stopper away from the outlet end , whereby the syringe is suitable for ophthalmic injection , wherein the variable volume chamber is filled with 40 mg/ml solution of aflibercept , and the dosage volume is 0.05 ml.19. The syringe according to claim 18 , wherein the stopper provides a sealing function by defining the rear of the variable volume chamber with a fluid tight seal claim 18 , which also provides a sterility seal.20. The syringe according to claim 18 , wherein the plunger ...

Sterilization of fluid paths in injection system

A contrast injector system includes one or more devices for reducing or eliminating risk of cross-patient contamination. In particular, the contrast injector system includes at least one of a sterilization device, vibration device, and illuminator device positioned on a component of the contrast injector system, where the sterilization device, vibration device, and/or illuminator device is in communication with a console of the contrast injector system. The sterilization device has an energy emitter positioned to emit energy to one or more components of the system. The vibration device is positioned on a component of the system so as to induce acoustic vibrations on a surface of such component. The illuminator device includes a light source positioned to illuminate a component of the system.

NEEDLELESS CONNECTOR AND ACCESS PORT DISINFECTION CLEANER AND ANTIMICROBIAL PROTECTION CAP

A protective cap having a first cap and a second cap that are removably coupled together for use in short-term and long-term antimicrobial treatment of needleless connectors and access ports of an infusion system. The instant invention further provides a protective cap having a first cap and a second cap that each coupled to a different surface of a component of an infusion system, such as a syringe. The instant invention further provides a strip containing a plurality of disposable protective caps. 1. A method for antiseptically maintaining a patient fluid line access valve , the method comprising:providing a syringe having a volume filled with an fluid for injection, the syringe having a nozzle encompassed by internal threads; having a cap having a first end and a second end, the first end comprising a first opening having a pad disposed therein wherein the cap second end is engaged to the syringe by a threaded engagement; wherein the first end is sealed by a removable lid covering the first opening;removing the removable lid covering thereby exposing the first opening;engaging the first opening to the patient fluid line access valve, thereby contacting the pad to a at least a portion of the patient fluid line access valve;disinfecting at least a portion of the patient fluid line access valve;disengaging the cap from the syringe nozzle by unthreading the cap from the syringe;connecting the nozzle of the syringe to the patient fluid line access valve; andinjecting the fluid for injection through the patient fluid line access valve.2. The method of claim 1 , wherein the removable lid comprises at least one of a foil lidding material and a polymer lidding material.3. The method of claim 1 , wherein the first opening is configured to receive an access portion of a patient fluid line access valve claim 1 , wherein the pad comprises an exterior surface that extends across the first opening and a cylindrical cut extending into the exterior surface to divide the pad into ...

MULTI-USE DRUG DELIVERY DEVICE FOR DRUGS WITH INSUFFICINET LEVEL OF PRESERVATIVES

A multi-use injection device () for multiple subcutaneous injections, wherein the injection device comprises a device main portion () and a multi-use needle unit () adapted to prevent unintended introduction of living microorganisms into a reservoir () of the device main portion during use of the injection device, and thereby promote bacteriostasis of a multiple-use drug preparation () during a use period with multiple injections. The drug delivery device () is adapted to enable multiple injections, without accidentally introducing living microbial contaminations into the reservoir during use, by adapting the multi-use needle to: (i) sterilize contaminations introduced into the distal needle after each exposure of a distal injection needle (), (ii) restrict diffusion and flow from the distal needle () to the reservoir () with a valve (), (iii), and by allowing the needle unit to remain mounted in the in-use configuration during the use period with multiple injections. 1. A multi-use injection device for multiple subcutaneous injections , wherein the injection device comprises a device main portion and a multi-use needle unit adapted to prevent unintended introduction of living microorganisms into a reservoir of the device main portion during use of the injection device , and thereby promote bacteriostasis of a multiple-use drug preparation during a use period with multiple injections:{'b': '110', 'claim-text': 'a cartridge comprising the reservoir with the multiple-use drug preparation for subcutaneous injection, wherein the multiple-use drug preparation comprises a mixture of substances that do not prevent growth of microorganisms if accidentally introduced into the reservoir with contaminations during use of the drug delivery device,', 'the device main portion () comprises a needle mount enabling the multi-use needle unit to be mounted and establish fluid communication with the reservoir by piercing the needle piercable membrane,', {'b': '444', 'dose setting ...

A MEDICAL INJECTION DEVICE

The invention relates to a pre-filled injection device for apportioning set dose of a liquid drug. The pre-filled injection device is of the type wherein a permanently mounted injection needle is cleaned in a cleaning reservoir between injections. The purpose of the invention is to provide a mechanism by which the cleaning reservoir can be filled with preservative containing liquid drug from the cartridge upon proximal movement of the needle hub in a linear movement. 1. A pre-filled injection device for ejection of individually set dose of a liquid drug ,comprising:a housing structure which externally supports a removable protective cap and internally supports a piston rod drive system,a non-replaceable cartridge permanently embedded in the housing structure and having an interior containing a preservative containing liquid drug, the interior being defined by a distal pierceable septum and proximal movable plunger movable by the piston rod drive system which comprises a piston rod for moving the movable plunger in the distal direction,the removable protective cap being coupled to the housing structure such that relative rotation between the removable protective cap and the housing structure is required in order to remove the removable protective cap, the first position being a position wherein the proximal end of the needle cannula is positioned distally spaced from the septum of the cartridge and,', 'the second position being a position wherein the proximal end of the needle cannula has penetrated through the septum of the cartridge thereby establishing a liquid flow through the lumen of the needle cannula,, 'a needle hub securing a needle cannula having a distal end with a distal tip and a proximal end and a lumen there between, which needle hub together with the needle cannula is movable from a first position to a second position,'}a needle shield covering at least the distal tip of the needle cannula between injections and which needle shield carries a cleaning ...

A MEDICAL INJECTION DEVICE WITH A CLEANING CHAMBER

The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided. The needle shield assembly is axially movable in a proximal direction in relation to the housing assembly from a first position to a second position upon rotation of at least a part of the needle shield assembly, wherein the first position is a position in which the distal tip of the needle cannula is located inside the cleaning chamber thereby cleansing the distal tip of the needle cannula, and the second position is a position in which the distal tip of the needle cannula is located outside and distal to the cleaning chamber for equalizing the pressure in the cartridge. 1. An injection device for injecting a liquid drug , comprising:a housing assembly supporting a non-removable cartridge having an interior chamber containing a liquid drug to be injected,a needle cannula connected to the cartridge and having a distal tip for penetrating the skin (S) of a user and a longitudinal lumen,a needle shield assembly which is provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections, wherein the first position is a position in which the distal tip of the needle cannula is located inside the cleaning chamber,', 'the second position is a position in which the distal tip of the needle cannula is located outside and distal to the cleaning chamber,, 'the needle shield assembly is movable in a proximal direction in relation to the housing assembly from a first position to a second position, ...

STERILE SEALED HETEROGENEOUS MEDICAMENT DELIVERY DEVICE

Apparatus and methods for delivering medicament to a patient. The apparatus may include elements with different capacities to attenuate or absorb sterilizing radiation. The apparatus may include a medicament delivery assembly with interactive elements for dose-setting, priming and medicament ejection. The assembly may include a chamber housing a radiation-sensitive medicament present in the apparatus during sterilization by electron beam. The assembly may include an actuator chassis, a drive mechanism, a needle-priming mechanism and a fluid-displacement mechanism including a fluid-displacement member. The chassis may be fixed, relative to an outlet, to the chamber. The member may be slidingly and/or threadingly engaged with the chassis, and may be configured to move relative to the outlet to deliver the medicament through the outlet. Assembly elements may be nested coaxially and/or stacked axially. The assembly may include at least one hollow region. The hollow region may reduce beam attenuation or reduce radiation absorption. 1. A medicament delivery apparatus comprising:a chamber containing a medicament, and having a medicament delivery outlet; a chassis that is fixed, relative to the outlet, to the chamber; and', 'a fluid-displacement member that is configured to move relative to the outlet to move the medicament through the outlet; and, 'a delivery assembly including sterilely surrounds the chassis; and', 'encloses no residue from chemical sterilization., 'an envelope that2. The apparatus of wherein the fluid-displacement member comprises a piston.3. The apparatus of wherein the fluid-displacement member comprises a flap.4. The apparatus of wherein the fluid-displacement member comprises an elastic energy storage device.5. The apparatus of wherein the fluid-displacement member comprises a permanent magnet.6. The apparatus of wherein the fluid-displacement member comprises an electromagnet.7. The apparatus of wherein the fluid-displacement member comprises a ...

Biostatic multi-use needle assembly for an injection device

A multi-use needle assembly (200) for an injection device (50), wherein the injection device (50) comprises: a housing (52) and a cartridge (54) for storing a liquid drug for multiple injections, the multi-use needle assembly comprises: a support structure (201), needle cannula (210), a movable shield assembly comprising a movable shield (220) and an actuation member (222) fixed to the shield (220), and a cleaning assembly (230) adapted to change configuration by deformation. The shield (220) is adapted to be in a locked distal position, an unlocked distal position and an unlocked proximal position, and the cleaning assembly (230) is adapted to be configured in (i) an open configuration, wherein a gap is provided between an outer surface of the cannula (210) and the cleaning assembly (230) to allow adjustment of the relative axial position between the cleaning assembly and the cannula, (ii) a closed configuration, wherein the cleaning assembly (230) is configured to provide contact with the outer surface of the cannula to enable cleaning of the cannula. The actuation member (222) is adapted to deform and thereby operate the cleaning assembly (230) between the open and the closed configuration, in response to turning the shield between the unlocked and the locked configuration. The needle assembly (200) is adapted to enable cleaning of the cannula (210), when the shield (220) is in the locked distal position, and to allow exposure of the cannula (210), when the shield (220) is in the unlocked distal position.

SYSTEMS AND METHODS FOR DETECTING AND TREATING BACTERIAL BIOFILMS

Impedance is detected between electrodes coupled to an indwelling medical device to monitor bacteria growth and/or formation of a bacterial biofilm in an in vivo environment. When an antimicrobial agent is present in the in vivo environment, the same voltage that enables impedance detection also generates a bioelectric effect, which decreases a size of the bacterial biofilm or inhibits growth of the bacterial biofilm. In some embodiments, the impedance detected between the electrodes can also be used as a feedback mechanism. When detection indicates that a bacterial biofilm has formed, the system can take remedial measures, such as introducing an antimicrobial agent to the in vivo environment and/or delivering a voltage higher than detecting voltage to deliver a greater bioelectric effect. In some embodiments, the electrodes can be formed on a flexible substrate that is mounted on and conforms to a non-flat surface of the indwelling medical device. 1. A method comprising:(a) delivering an antimicrobial agent to an in vivo environment in which an indwelling medical device is disposed;(b) during a first time period, measuring a first impedance value by applying a first AC voltage signal to electrodes disposed over a surface of the indwelling medical device, the first AC voltage signal having a first frequency in a range of 100 Hz to 2 kHz and a first amplitude;(c) generating an indication of positive bacteria growth on the indwelling medical device in response to the first impedance value being less than a previously measured impedance value; and(d1) applying a second AC voltage signal to the electrodes in response to the indication of positive bacteria growth or in response to the first impedance value being outside of a first predetermined range,wherein the applying the first AC voltage signal to the electrodes in the presence of the antimicrobial agent generates a first bioelectric effect, in which efficacy of the antimicrobial agent in decreasing a size of a ...

MEDICAL APPARATUS AND METHOD FOR STERILIZING MEDICAL APPARATUS

According to embodiments, there is provided a medical apparatus including one or more sterile pre-filled syringe, one or more first protective container including the one or more sterile pre-filled syringe, wherein the first protective container may be completely or partially filled with an inert or non-inert gas, wherein the one or more first protective container is impermeable to moisture and/or sterilizing agents, and a second protective container including one or more medical components and the one or more first protective container, wherein the second protective container may be, but is not necessarily, completely or partially filled with an inert or non-inert gas. In some aspects, a package mostly impermeable to bacteria including the first and second protective containers is also completely or partially filled with an inert or non-inert gas. 1. A process for providing a sterilized medical apparatus , the process comprising:Partially or completely filling a first protective container comprising one or more sterilized syringe, packaged or unpackaged, with a gas, wherein the gas is capable of creating, improving, and/or maintaining a sterile environment within a cavity of the first protective container;Sealing the first protective container;Packaging the first protective container within a cavity of a second protective container; andSterilizing the second protective container and the contents within the cavity of the second protective container.2. The process for providing a sterilized medical apparatus according to claim 1 , wherein the gas is an inert gas.3. The process for providing a sterilized medical apparatus according to claim 1 , further comprising pressurizing the first protective container to at or less than about 45 pounds per square inch (PSI).4. The process for providing a sterilized medical apparatus according to claim 1 , wherein the first or second sterilized container is chosen from one or more of a tube claim 1 , can claim 1 , bag claim 1 , ...

Injection Device with a Needle Cannula

The present invention relates to an injection device for injecting a pharmaceutical liquid drug containing a preservative. The injection device comprises a housing ( 1 ) supporting a cartridge ( 20 ) having an interior chamber ( 21 ) holding the pharmaceutical preservative containing liquid drug to be injected, and a needle cannula ( 10 ) having a front part ( 11 ) and a back part ( 12 ), which back part ( 12 ) is adapted to be in liquid communication with the interior chamber ( 21 ) of the cartridge ( 20 ). The injection device is further provided with a telescopic needle covering shield ( 30 ) which distally is provided with a reservoir ( 31 ) which holds a liquid containing the same preservatives as in the pharmaceutical preservative containing liquid drug contained in the interior chamber of the cartridge. The telescopic needle covering shield ( 30 ) is telescopic movable in relation to the needle cannula ( 10 ) by a first resilient member between a first position and a second position. In the first position, the tip ( 13 ) of the front part ( 11 ) of the needle cannula ( 10 ) is maintained inside the reservoir ( 31 ), and in the second position, the tip ( 13 ) of the front part ( 11 ) of the needle cannula ( 10 ) is located outside the reservoir ( 31 ) and distally to the reservoir ( 31 ). The tip ( 13 ) of the needle cannula ( 10 ) is thus cleaned by the preservatives in the reservoir ( 31 ) between subsequent injections.

PROTECTIVE DEVICE FOR A SYRINGE NEEDLE

A protection device for a syringe needle, having an elastomeric cap. The cap defining a housing receiving the distal portion of the body of a needle syringe. An end wall of the cap perforatable over a fraction of its thickness by the free end of the needle. The housing having a first segment of frustoconical or cylindrical shape; a cylindrical second segment for housing the distal portion of the syringe body that carries the needle, and a third segment that tapers from the second segment towards the end wall of the housing, the lateral wall provided with an annular bead arranged in the housing, at least one slot extending in a longitudinal direction across the annular bead. The second segment includes at least one axial groove that extends longitudinally over a fraction of the height of the second segment. 12024222028223226104102100302434301062622. A protection device for protecting a syringe needle , the device comprising an elastomeric needle cap () that extends in a generally longitudinal direction and that has a closed distal end () and an open proximal end () , said cap () comprising a lateral wall () that extends from said proximal end () along a proximal end zone () , defining an internal housing () for receiving the distal portion () of the body () of a needle syringe () , and an end wall () having a thickness that extends from said distal end () along a distal end zone () , said end wall () being suitable for being perforated over a fraction of its thickness by the free end of said needle () , said housing () comprising , from said proximal end ():{'b': 36', '1, 'an opening () that presents a maximum diameter (D);'}{'b': '40', 'a first segment () of frustoconical or circularly cylindrical shape;'}{'b': 42', '2', '1', '104', '102', '106, 'a circularly-cylindrical second segment () that presents a diameter (D) that is less than said maximum diameter (D), and that is for housing the distal portion () of the syringe body () that carries said needle (); and'}{'b ...

System for Integrating an Antibacterial-Element Receptacle into an Autoinjector Cap

A system for integrating an antibacterial-element receptacle into an autoinjector cap facilitates the pre-injection treatment, the post-injection treatment, and prevents the accidental delivery of the injection. The system includes a cap assembly, an autoinjector body, and an antiseptic-soaked dressing. The cap assembly encloses the needle of the autoinjector and prevents the accidental trigger of the injection mechanism. The autoinjector body refers to the body of any conventional autoinjector. The antiseptic-soaked dressing is applied to the patient's skin prior to the delivery of the injection to disinfect and sterilize the injection area. The antiseptic-soaked dressing is housed in the cap assembly, between a receptacle and a removable cover. The removable is releasably mounted to the receptacle to allow access to the antiseptic-soaked dressing. 1. A system for integrating an antibacterial-element receptacle into an autoinjector cap comprises:a cap assembly;an autoinjector body;an antiseptic-soaked dressing;the cap assembly comprises a receptacle, a removable cover, a cover fastener, and a coupling interface;the removable cover being attached across an opening of the receptacle by the cover fastener;the coupling interface being connected adjacent to the receptacle, opposite the removable cover;the coupling interface being engaged to the autoinjector body; andthe antiseptic-soaked dressing being mounted in between the removable cover and the receptacle.2. The system for integrating an antibacterial-element receptacle into an autoinjector cap as claimed in claim 1 , wherein the coupling interface is a slip-fit fastener.3. The system for integrating an antibacterial-element receptacle into an autoinjector cap as claimed in comprises:the antiseptic-soaked dressing being connected into the receptacle; andthe antiseptic-soaked dressing traversing out of the opening of the receptacle.4. The system for integrating an antibacterial-element receptacle into an autoinjector ...

INJECTION DEVICE WITH A NEEDLE CANNULA

The present invention relates to an injection device for injecting a pharmaceutical liquid drug containing a preservative. The injection device comprises a housing () supporting a cartridge () having an interior chamber () holding the pharmaceutical preservative containing liquid drug to be injected, and a needle cannula () having a front part () and a back part (), which back part () is adapted to be in liquid communication with the interior chamber () of the cartridge (). The injection device is further provided with a telescopic needle covering shield () which distally is provided with a reservoir () which holds a liquid containing the same preservatives as in the pharmaceutical preservative containing liquid drug contained in the interior chamber of the cartridge. 1. An injection device for injecting a pharmaceutical liquid drug containing a preservative , comprising:a housing supporting a cartridge permanently embedded in the injection device, the cartridge having an interior chamber containing the pharmaceutical preservative containing liquid drug to be injected,a needle cannula permanently secured to the injection device, and usable for multiple injections and having a front part with a tip and a back part, which back part is adapted to be in liquid communication with the interior chamber of the cartridge, and the first position being a position in which, the tip of the front part of the needle cannula is located inside the reservoir, and', 'the second position being a position in which, the tip of the front part of the needle cannula is located outside the reservoir and distally to the reservoir,, 'a telescopic needle covering shield, which distally is provided with a reservoir confining a predetermined volume of a liquid for cleaning at least the tip of the needle cannula between subsequent injections, and which telescopic needle covering shield is urged distally into a first position by a first resilient member and moved proximally against the bias of the ...

LOCAL DISINFECTION FOR DRUG DELIVERY SYSTEM

Apparatus and a method are presented, including disinfecting a disinfection chamber that is defined between (i) a prefilled therapeutic substance reservoir and (ii) a sterile fluid path disposed within a therapeutic substance delivery device. The sterile fluid path includes a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path. The disinfection occurs subsequently to the prefilled therapeutic substance reservoir being engaged with the therapeutic substance delivery device. Subsequently to disinfecting the disinfection chamber, the disinfection chamber and then the reservoir are penetrated with the needle. Other applications are also described. 1. A method comprising: 'the disinfecting occurring (a) subsequently to the prefilled therapeutic substance reservoir being engaged with the therapeutic substance delivery device and (b) prior to the penetrating of the disinfection chamber and then the reservoir with the needle.', 'the sterile fluid path comprising a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path; and penetrating the disinfection chamber and then the reservoir with the needle,'}, 'using a disinfection assembly disposed within a therapeutic substance delivery device, disinfecting a disinfection chamber that is defined between (i) a prefilled therapeutic substance reservoir and (ii) a sterile fluid path disposed within the therapeutic substance delivery device,'}2. The method according to claim 1 , wherein the step of disinfecting the disinfection chamber is performed following a user of the therapeutic substance delivery device engaging the prefilled therapeutic substance reservoir with the therapeutic substance delivery device claim 1 , wherein the disinfection chamber is defined when the prefilled therapeutic substance reservoir becomes engaged with the therapeutic substance delivery device.3. The method ...

Method and Apparatus for Manufacturing, Filling and Packaging Medical Devices and Medical Containers

Medical devices such as medical containers can be formed of glass and annealed which produces a clean device having a low bio-burden, or formed by plastic molding which produces a clean device. The clean devices are immediately transferred to a controlled environment such as a clean room or localized area to avoid the need to maintain cleanliness levels in an entire room. Syringe tip closures can be introduced into the housing assembly, where syringe barrels and tip closures are cleaned with filtered ionized air and the tip closures are coupled to the barrels. The syringe barrels can be filled with a substance and a closure member attached. While still in the housing assembly the syringe barrels can be formed into an array and placed in a clean outer container, which is then closed and sealed.

PREFILLED SYRINGE AND METHOD OF PREPARING A PREFILLED SYRINGE

A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. 119-. (canceled)21. The method of claim 20 , wherein the main step of the first sterilizing is performed in a sterilization chamber.22. The method of claim 20 , wherein the main step of the first sterilizing comprises exposing the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel to a pressure of about 450 millibars to about 1000 millibars.23. The method of claim 20 , wherein in the main step of the first sterilizing claim 20 , the ethylene oxide is provided in a concentration of about 400 milligrams per liter to about 800 milligrams per liter.24. The method of claim 20 , wherein the main step of the first sterilizing comprises flushing the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel with air claim 20 , nitrogen or a combination thereof at a pressure of about 100 millibars or about 200 millibars to about 800 millibars or about 900 millibars after exposing the syringe barrel together with the needle adaptor cap to ethylene oxide.25. The method of claim 20 , wherein the first sterilizing comprises a pre- ...

Medical device for fluid delivery having reduced dead space

Disclosed herein is a pharmaceutical syringe having a cylindrical bore with a proximal opening, the syringe comprising a distal wall of the bore defining an outlet biased from the central axis of the syringe, and toward a first area of the distal wall and biased from the central axis away from a second area distinct from the first area; the syringe comprising a plunger seal having a distal surface; wherein when the plunger seal is fitted into the bore with the distal surface facing an inner surface of the distal wall of the bore, the second area of the inner surface is axially closer to the distal surface of the plunger seal than the first area, in a direction parallel to the central axis of the cylindrical bore, such that fluid is expelled from the second area and towards the outlet.

DEVICE PORT CLEANER

The present invention includes a device cleaner, and method of use, for cleaning a device port, particularly a medical device port, that may be inserted into the device port cleaner for cleaning and/or disinfecting. 1. A port cleaner for cleaning a device port , comprising:a reservoir comprising a housing having an opening and a reservoir flange formed along the opening end of the reservoir and extending outwards away from the interior of the reservoir;a membrane affixed over the opening of the reservoir;wherein the membrane further comprising a membrane flange extending circumferentially outwards;wherein the membrane and reservoir are configured to couple together with the bottom surface of the membrane flange contacting the top surface of the reservoir flange;wherein the membrane comprises internal threading extending into the reservoir and configured to be threaded onto a device port and secure the device port from withdrawal; andwherein the membrane further comprises a lip ring, the lip ring configured to contact a device port and form a seal when the device port is inserted into the membrane.2. The port cleaner of claim 1 , wherein the membrane further comprises an elastic material.3. The port cleaner of claim 1 , further comprising a release mechanism within the reservoir for retaining and releasing a disinfecting agent.4. The port cleaner of claim 3 , wherein the release mechanism is configured to engage a device port and dispense the disinfecting agent when the device port is inserted into the reservoir.5. The port cleaner of claim 4 , wherein the release mechanism further comprises a compressible material that when compressed by the device port releases the disinfecting agent.6. The port cleaner of claim 1 , further comprising a lid configured to fit over the reservoir opening and the membrane.7. The port cleaner in claim 1 , further comprising:a series of membrane perforations through the membrane flange; anda series of reservoir extrusions extending from ...

Antiseptic Cap Equipped Syringe

A syringe assembly including: (1) a syringe barrel defining a chamber; (2) a plunger mounted in the chamber and moveable with respect to the barrel; and (3) a cap holder assembly containing a cap and an absorbent material removably attached to the syringe.

A Drug Delivery Device with a Cap

A needle assembly for use with a drug delivery device comprises a cap releasably secured to the drug delivery device and a blocking member. The blocking member comprises a disinfectant swab and a user graspable portion. The blocking member is configured to be physically moved with respect to the needle assembly by a user. The needle assembly is configured such that in an initial position, the blocking member blocks the cap from being removed from the drug delivery device and movement of the blocking member from the initial position causes the disinfectant swab to contact a septum of a cartridge retained within the drug delivery device. 115-. (canceled)17. The needle assembly according to claim 16 , wherein the blocking member comprises a removable sterile seal covering the disinfectant swab.18. The needle assembly according to claim 17 , wherein the sterile seal is configured to be physically removed by a user prior to movement of the blocking member.19. The needle assembly according to claim 17 , wherein the sterile seal is configured to be physically removed by removal of the blocking member.20. The needle assembly according to claim 19 , wherein the sterile seal is secured at one end to an outer body of the cap to cause removal of the sterile seal from the disinfectant swab claim 19 , when the blocking member is removed.21. The needle assembly according to claim 16 , the cap comprising opposing apertures claim 16 , which the blocking member is configured to pass through and occupy when in the initial position.22. The needle assembly according to claim 16 , the needle assembly further comprising a needle holder and a sleeve claim 16 , wherein the needle holder is configured to move axially within the sleeve and wherein the sleeve is retained within the cap.23. The needle assembly according to claim 22 , wherein the sleeve comprises one or more resiliently deformable clips configured to retain the needle holder in a first position claim 22 , and24. The needle ...

AN INJECTION DEVICE WITH A CLEANING RESERVOIR

The invention relates to a medical injection device for injection of a liquid drug. The injection device comprises a housing structure with a cartridge and needle cannula. Further an axially movable cleaning reservoir is provided which is movable in relation to the housing structure, and which cleaning reservoir contains a liquid cleaning agent. The distal tip of the needle cannula is positioned and thus cleaned inside the cleaning reservoir between subsequent injections. According to the invention, the cleaning reservoir connects to an overflow reservoir through a one-way pressure valve such that the cleaning agent and/or air is flowable from the cleaning reservoir and into the overflow reservoir. 1. A medical injection device for injection of a liquid drug , comprising:a housing structure supporting a cartridge containing the liquid drug, wherein the cartridge comprises a plunger which is movable in a distal direction inside the cartridge to thereby pressurize the liquid drug contained in the cartridge,a needle cannula having a distal part with a distal tip and a longitudinal lumen, the needle cannula being mounted relatively to the housing structure such that the distal tip extend in a distal direction and wherein the needle cannula proximally connects to the cartridge at least during injection,an axially movable cleaning reservoir movable in relation to the housing structure, and which cleaning reservoir connects to an overflow reservoir and contains a liquid cleaning agent, and wherein the distal tip of the needle cannula is positioned inside the cleaning reservoir at least between injections,wherein an overflow reservoir is connected to the cleaning reservoir through a one-way pressure valve comprising a flexible element changeable from a default closed state to an activated open state,and wherein the flexible element in the default closed state seals off the cleaning reservoir and in the activated open state allow the cleaning agent and/or air to flow from ...

PREFILLED SYRINGE AND METHOD OF PREPARING A PREFILLED SYRINGE

A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. 123-. (canceled)24. A method of preparing a prefilled syringe , comprising:obtaining a syringe barrel having an open end and a tip with an orifice essentially opposite to the open end, and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing comprising a main step of exposing the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel to ethylene oxide;filling a drug substance through the open end of the syringe barrel or through the orifice of the syringe barrel into an interior of the syringe barrel;sealing the interior of the syringe barrel by advancing a rubber stopper through the open end of the syringe barrel;packaging the syringe barrel together with the rubber stopper sealing the interior of the syringe barrel and the needle adaptor cap assembled on the tip of the syringe barrel; andsecond ...

DEVICES, SYSTEMS, AND METHODS OF PACKAGING FOR A PRE-FILLED DRUG DELIVERY DEVICE

A system for sterilizing a drug delivery device includes a drug delivery device having a first self-healing seal configured to seal a fluid reservoir disposed within the drug delivery device. A sealable container is configured to receive the drug delivery device therein. The sealable container has a base portion and a cover portion. The cover portion has a second self-healing seal positioned to align with the first self-healing seal when the drug delivery device is disposed within the sealable container. A fill port includes a fill path, the fill path being configured to pass through the first and second self-healing seals to fluidly couple the fill port to the reservoir of the drug delivery device. Other systems, methods, and devices of sterilization are also disclosed. 1. A method comprising:providing a drug delivery device within a sealable container, the drug delivery device having an empty reservoir and a first self-healing seal;coupling a fill path to the reservoir by disposing the fill path through the first self-healing seal in the drug delivery device and through a second self-healing seal in the sealable container;interfacing a fill nozzle of a liquid drug dispensing system with the fill path of the drug delivery device; andsupplying, via the fill nozzle and the fill path, a liquid drug into the reservoir of the drug delivery device.2. The method of claim 1 , further comprising:disengaging the fill path from the drug delivery device by removing the fill path from the first self-healing seal and the second self-healing seal.3. The method of claim 1 , further comprising:aligning the first self-healing seal with the second self-healing seal.4. The method of claim 1 , further comprising:applying ethylene oxide, steam or gamma radiation to the drug delivery device, sealable container, and fill path.5. The method of claim 1 , further comprising:prior to providing the delivery device within the sealable container, positioning the first self-healing seal of the ...

A PREFILLED INJECTION DEVICE WITH CLEANING CHAMBER

The invention relates to a prefilled injection pen for apportioning multiple set doses of a liquid drug containing a preservative. The injection pen comprises a housing structure which permanently and non-removable secures a cartridge containing the preservative containing liquid drug. The cartridge is connected to a needle cannula which further has a sharp distal tip for penetrating the skin of a user. The distal tip of the needle cannula is concealed by an axially movable needle shield at least between injections. At the distal end of the axially movable needle shield, a cleaning chamber is provided which cleaning chamber contains a volume of the same preservative containing liquid drug as present in the cartridge. The cleaning chamber is further provided with an outlet which is open to the surroundings and through which outlet air and a quantum of the preservative containing liquid drug can escape. In the proximity of the outlet, means are provided to collect the escaped quantum of the preservative containing liquid drug. 1. A prefilled injection device for delivering doses of a preservative containing liquid drug comprising:a housing structure permanently securing a non-exchangeable cartridge containing the preservative containing liquid drug,a needle cannula having a distal part and a proximal part and wherein the proximal part connects to the cartridge at least during dose expelling, and the distal part terminates in a distal tip for penetrating the skin of a user,a movable needle shield which is axially movable in relation to the housing structure between a first position and a second position,a cleaning assembly carried by the axially movable needle shield, which cleaning assembly comprises a cleaning chamber containing a volume of the same preservative containing liquid drug as present inside the cartridge and which cleaning chamber is provided with an outlet through which a quantum of the preservative containing liquid drug is escapable,wherein the distal ...

Shielding Mechanism for an Injection Apparatus

The present invention relates to an injection apparatus for injecting a pharmaceutical liquid drug into the skin of a user. The injection apparatus can be in form of an injection device carrying a needle cannula or in the shape of a needle assembly ( 10 ) attachable to an injection device. The outer shell of the injection apparatus is a protective shield ( 10 ) divided into different segments ( 10 a, 10 b ). These segments are preferably spaced from each other in the longitudinal direction to move individually in the axial direction. Further, the segments are provided with tilting means ( 14, 15 ) which are activated to move neighboring segments ( 10 a, 10 b ) apart upon relative axial movement of one or more segments ( 10 a, 10 b ) whenever an uneven force is applied to the distal end of the shield.

CLEANING A PLURALITY OF NEEDLES, POST MANUFACTURE AND BEFORE ASSEMBLY INTO A SYRINGE, CANNULA AND THE LIKE

A system for cleaning a plurality of needles includes a conveyor for conveying a plurality of jigs through a series of stations, and each jig is arranged to contain at least some of the needles. The stations include a pre-treatment station for the removal of detritus from the needles, an electronic polishing station, a post-treatment station for removal of material from the surface of the treated needles, a cleaning station for cleaning the needles, a drying station, and an unloading station for unloading the needles from the jigs.

MEDICAL APPARATUS PACKAGE

A package () for components of a medical apparatus comprising a plurality of panels (-) defining a container () having an interior space. A first component of the medical apparatus is disposed within the interior space. The first component of the medical apparatus comprises a medicament delivery device. The container () comprises a base panel () which forms a bottom wall of the container (). At least one lid panel () is connected to the base panel () and is foldable into a position in which it extends coplanar with the base panel () when the container () is manipulated into an open configuration. At least one lid panel () includes a sterile surface forming a preparation surface upon which a user may place components of a medical apparatus when the container () is in the open configuration. Also disclosed is a medical apparatus comprising such a package with a container of medicament () within the interior space of the container (). 110. A package () for components of a medical apparatus comprising:{'b': 12', '20', '11, 'a plurality of panels (-) defining a container () having an interior space; and'}{'b': '25', 'claim-text': {'b': 11', '12', '11, 'wherein the container () comprises a base panel () which forms a bottom wall of the container (); and'}, 'a first component of the medical apparatus disposed within the interior space, the first component of the medical apparatus comprising a medicament delivery device ();'}{'b': 16', '12', '12', '11, 'at least one lid panel () which is connected to the base panel () and is foldable into a position in which it extends co-planar with the base panel () when the container () is manipulated into an open configuration; and'}{'b': 16', '11, 'wherein the at least one lid panel () includes a sterile surface forming a preparation surface upon which a user may place components of a medical apparatus when the container () is in the open configuration.'}21016. A package () according to wherein the sterile surface comprises a coating ...

PORTABLE UV-C SYRINGE SANITIZER

A portable syringe sanitizer kit has a longitudinal housing having a sanitization area, a compartment for retaining at least one source of electricity, and mechanisms for retaining a needle, barrel, and plunger of a syringe. A source of germicidal radiation, such as a UV-C light, is disposed in the housing, the source of germicidal radiation being electrically connected to a source of electricity, such as one or more batteries. A switch operatively connected to the source of electricity and to the source of germicidal radiation can initiate activation of the radiation. A syringe holder tube and a mechanism for retaining a syringe plunger are also provided. The source of germicidal radiation generates light having a wavelength of between approximately 200 nm and 280 nm. The housing is mounted in an eyeglass case. A timing device de-energizes the source of radiation after a predetermined interval of time. 1. A portable syringe sanitizer kit comprising:a) a longitudinal housing having a sanitization area, a compartment for retaining at least one source of electricity, and means for retaining a needle, barrel, and plunger of a syringe;b) a source of UV-C light disposed in said housing, said source of UV-C light being electrically connected to said at least one source of electricity; andc) a switch operatively connected to said at least one source of electricity and to said source of UV-C light for initiating activation thereof.2. The portable syringe sanitizer kit in accordance with claim 1 , further comprising:d) a syringe holder tube.3. The portable syringe sanitizer kit in accordance with claim 1 , further comprising:d) means for retaining a syringe plunger.4. The portable syringe sanitizer kit in accordance with claim 1 , wherein said source of UV-C light is one of the group: an LED device claim 1 , a laser claim 1 , an electric arc claim 1 , a xenon bulb claim 1 , a halogen bulb claim 1 , an excimer bulb claim 1 , and a mercury vapor lamp.5. The portable syringe ...

A MEDICAL INJECTION DEVICE HAVING A SEALABLE CLEANING RESERVOIR

The present invention concerns a medical injection device for apportioning set doses of a preservative containing liquid drug. The injection device comprises a housing supporting a cartridge containing the preservative containing liquid drug and a needle cannula for transferring the liquid drug from the cartridge and through the skin of a user. Further, a needle shield which is axially movable in relation to the housing is also present. The axially movable shield carries a cleaning reservoir for cleaning at least the tip of the needle cannula between subsequent injections and the cleaning reservoir is preferably filled with preservative containing liquid drug directly from the cartridge upon initiation of the injection device. In order to eliminate any overpressure being built up inside the cleaning reservoir during the filling process, the cleaning reservoir is provided with an outlet configured to be permanently sealed by a user activated operation. 1. A medical injection device for apportioning doses of a preservative containing liquid drug , comprising:a housing supporting a cartridge containing the preservative containing liquid drug,a needle cannula having a distal part with a distal tip and a proximal part and a longitudinal lumen there between, the needle cannula being mounted relatively to the housing such that the distal part extend in a distal direction and the proximal part extend in a proximal direction and into the cartridge at least during injection,an axial movable shield which is axial movable in relation to the housing from a first position to a second position and which axial movable shield carries a cleaning reservoir which distally is sealed by a distal pierceable seal and proximally by a proximal pierceable seal longitudinal spaced from each other and which cleaning reservoir is filled with an amount of the same preservative containing liquid drug as present in the cartridge, wherein the distal tip of the needle cannula in the first position is ...

COVERS FOR DRUG CONTAINER PISTON ARRAYS OR PISTON NESTS AND PACKAGES FOR COVER AND PISTON NEST ASSEMBLIES

A cover for a drug container piston array includes a plurality of cover sections configured for positioning over the drug container piston array. Each cover section includes an elongated cover section body having an open base end and a closed capped end, and a plurality of base sections or a web positioned between the plurality of cover sections and coupled to each base end. Packaging assemblies including a cover and a piston nest are also disclosed. 1. A cover for a drug container piston array or piston nest , comprising: an elongated cover section body, having an open base end and a closed capped end, and', 'a plurality of base sections positioned between the plurality of cover sections and coupled to each base end., 'a plurality of cover sections configured for positioning over the drug container piston array, each cover section comprising'}2. The cover of claim 1 , wherein at least two of the plurality of cover sections are laterally offset with respect to one another.3. The cover of claim 1 , further comprising a plurality of cover reinforcements positioned between at least two of the plurality of cover sections.4. The cover of claim 3 , wherein at least one of the plurality of cover reinforcements is coupled to an outer wall surface of each of the plurality of cover sections.5. The cover of claim 1 , further comprising at least one cover end reinforcement positioned between at least two of the plurality of cover sections and coupled to the base end of at least two cover sections.6. The cover of claim 5 , wherein the at least one cover end reinforcement is coupled to an outer wall surface of at least one cover section.7. The cover of claim 1 , further comprising a plurality of piston locators positioned in intervals along the elongated cover section body.8. The cover of claim 7 , wherein each of the piston locators of the plurality of piston locators is configured to engage and at least partially orient the drug container piston array.9. The cover of claim 1 , ...

Methods for manufacturing non-glass prefilled syringes

A method of sterilizing a prefilled syringe comprises assembling a syringe assembly and performing at least one ethylene oxide (EtO) sterilization procedure cycle. The assembling step includes inserting a tip cap at a first end of a plunger, filling a non-glass barrel with sterilization sensitive material at a second end of the barrel, and inserting the plunger into the barrel at a second end to seal the sterilization sensitive material within the barrel. The EtO sterilization procedure cycle comprises undergoing a preprocessing stage, a wash and conditioning stage, an EtO sterilization stage and a wash and post exposure stage. Upon completing the EtO sterilization procedure cycle, a resultant pH of the sterilization-sensitive material does not exceed an acceptable pH range as defined by the United States Pharmacopeia. The disclosure also discusses inserting an assembled prefilled syringe into a procedure tray prior to performing the EtO sterilization procedure cycle.

ANTISEPTIC CAP EQUIPPED SYRINGE

A syringe assembly including: (1) a syringe barrel defining a chamber; (2) a plunger mounted in the chamber and moveable with respect to the barrel; and (3) a cap holder assembly containing a cap and an absorbent material removably attached to the syringe. 1contacting a cap holder of a cap holder assembly, at a bottom surface thereof, through an aperture in the chamber;urging, through the aperture, the cap holder assembly out of the chamber;removing the cap holder assembly from the syringe plunger; andstoring the cap holder assembly for use in the future.. A method of using an antiseptic cap disposed on a plunger of a syringe having a chamber at a proximal end, comprising: This application is a continuation application of U.S. patent application Ser. No. 13/547,650, filed on Jul. 12, 2012, which is a continuation-in-part of U.S. patent application Ser. No. 13/288,529, filed on Nov. 3, 2011, which is a continuation-in-part of U.S. application Ser. No. 12/214,526, filed on Jun. 19, 2008, which is a continuation-in-part of U.S. application Ser. No. 11/821,190 filed on Jun. 22, 2007, now U.S. Pat. No. 8,167,847, which claims the benefit of U.S. Provisional Application Ser. No. 60/815,806 filed on Jun. 22, 2006, and U.S. patent application Ser. No. 13/288,529 is a continuation-in-part of U.S. application Ser. No. 11/821,190 filed on Jun. 22, 2007, now U.S. Pat. No. 8,167,847, which claims the benefit of U.S. Provisional Application Ser. No. 60/815,806 filed on Jun. 22, 2006, the entire disclosures of which are all expressly incorporated herein by reference.The present invention relates to an antiseptic cap equipped syringe, and more specifically to antiseptic caps disposed on syringes.Catheters are widely used to treat patients requiring a variety of medical procedures. Catheters can either be acute, or temporary, for short-term use or chronic for long-term treatment. Catheters are commonly inserted into central veins (such as the vena cava) from peripheral vein sites to ...

Sanitizing Device

A sanitizing device used to sanitize a bulb syringe. The device preferably includes a base, a bulb receiver, and a sanitization system. The sanitization system produces a sanitizing gas that is propelled into and possibly around a bulb syringe in order to sanitize the surfaces of the syringe. The sanitization system preferably includes an ionization module, a fan, electrodes, and a power supply. Preferably, the sanitization system is housed in a conical housing which includes a central nozzle and an array of openings centered around the nozzle exit. The sanitization device preferably includes an automatic switch that is activated by the presence of a bulb syringe or upon placing a cover over the device.

An Injection Device With Needle Cleaning

The invention relates to a medical injection device having a needle cannula for multiple use and which needle cannula is cleaned between subsequent injections. The needle cannula is preferably cleaned at the distal tip in a cleaning assembly having a hollow cleaning chamber with a variable volume. The distal tip of the needle cannula is maintained inside the cleaning chamber between subsequent injections. The cleaning chamber is defined by an inner surface, a distal seal and a proximal seal. In order to increase the volume of the cleaning chamber during filling of the cleaning chamber one of the seals is formed as a movable plunger which is movable in one direction to expand the volume of the cleaning chamber. To release the movable plunger from the inner surface of the hollow cleaning chamber in order to commence the filling of the cleaning chamber, the movable plunger and the inner wall surface of the hollow cleaning chamber are rotatable in relation to each other during filling of the cleaning chamber. 1. A medical injection device for injection of a liquid drug , comprising:a housing structure supporting a cartridge containing the liquid drug,a needle cannula mounted relatively to the housing structure such that a distal tip extend in a distal direction and a proximal part extend in a proximal direction and connects with the cartridge at least during injection,a cleaning assembly comprising a chamber part with a hollow cleaning chamber having a variable volume and defined by an inner surface, a distal seal and a proximal seal, whereinone of the distal seal or proximal seal comprises a movable plunger which is movable in one direction to thereby expand the variable volume of the hollow cleaning chamber and wherein the movable plunger and the inner wall surface of the hollow cleaning chamber are rotatable in relation to other.2. A medical injection device for injection of a liquid drug according to claim 1 , wherein the cleaning assembly is secured to an ...