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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 23716. Отображено 100.
19-01-2012 дата публикации

Methods for exposing and using a swab

Номер: US20120012631A1
Принадлежит: INTRAvENA LLC

A method for remotely applying a force to a tether affixed to a sterilizing swab package to open the package for use of a swab disposed therein. The method may be applied to sterilizing a septum of a vial disposed within a bag.

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26-01-2012 дата публикации

Filter device and liquid injection apparatus having the same

Номер: US20120022449A1
Автор: Yong-Nyun Kim
Принадлежит: E Wha Fresenius Kabi Inc

A filter device of the present invention includes a hydrophilic filter located in a vertical space in a filter housing to filter off solid impurities in an introduced liquid, at least one hydrophobic filter located corresponding to at least one gas discharge hole provided in the filter housing, the hydrophobic filter allowing gas in the introduced liquid to be discharged to the outside before and/or after the liquid passes through the hydrophilic filter, and a blocking member for preventing gas in the liquid passing through the hydrophilic filter from flowing into the outlet tube, the blocking member being installed in the filter housing to block the outlet tube, the blocking member having a longitudinal passage formed in a center portion thereof so that the liquid is introduced into the outlet tube through the passage and discharged therefrom. According to the present invention, there are advantages in that the filter device can effectively remove air and impurities such as solid particles contained in a liquid such as a medicine, prevent the air in the medicine from flowing into an extension tube connected to the filter device, and ensure a maximum surface area of a hydrophilic filter for filtering off solid particles such as glass fragments so that a flow rate of a medicine passing through the filter device does not decrease.

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02-02-2012 дата публикации

Device for the administration of injectable products with a controlled flow rate

Номер: US20120024987A1
Принадлежит: INNOVA SALUD DESARROLLOS SANITARIOS SL

A device is for the administration of injectable products with controlled flow rate, with a container ( 23 ) in the form of both a syringe and an ampoule preloaded with the injectable product, an injection port ( 25 ) and a control valve ( 21 ) for controlling the outlet rate and pressure arranged between the injectable products and the injection port ( 25 ). A device for reducing the outlet flow rate depends on the pressure increase applied during the administration of the injectable product, the administration being moderated by closing the valve ( 21 ) when the pressure exceeds a predetermined limit. A device prevents the backflow of fluids during the administration of the injectable product. The valve ( 21 ) can be positioned both in the container ( 23 ) and at an injection end ( 27 ) including the injection port ( 25 ) which is coupled to the container ( 23 ).

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02-02-2012 дата публикации

Modular infusion set with an integrated electrically powered functional component

Номер: US20120029333A1
Принадлежит: ROCHE DIAGNOSTICS INTERNATIONAL AG

An infusion set for administering a medicament delivered by an infusion pump which can be carried separately from the infusion set as well as an infusion system including the infusion set are disclosed. The infusion set can comprise a disposable part, a reusable part, and an electrically powered functional component. The disposable part can comprise a single lumen infusion cannula that projects from the underside and is the only skin piercing or penetrating element of the infusion set. The reusable part when in the interconnected state is fluidically isolated from the disposable part. The disposable part can comprise a feeding line which fluidically connects an upstream end of the first connector with a downstream end of a cannula to feed and deliver the medicament via the disposable part and bypass the reusable part.

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16-02-2012 дата публикации

Devices and methods for respiratory variation monitoring by measurement of respiratory volumes, motion and variability

Номер: US20120041279A1
Принадлежит: Respiratory Motion Inc

This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.

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16-02-2012 дата публикации

Method and apparatus for detecting occlusions in an ambulatory infusion pump

Номер: US20120041370A1
Принадлежит: Medtronic Minimed Inc

An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. A method, system, and an article of manufacture for automatically detecting an occlusion in a medication infusion pump is provided. The electrical current to an infusion pump is measured. Based on a series of measurements of one or more variables, the infusion pump detects whether there is an occlusion in the system.

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08-03-2012 дата публикации

Implantable drug delivery devices

Номер: US20120059349A1
Принадлежит: Pharmanova Inc

The invention relates generally to implantable drug delivery devices. Devices having a single drug chamber configuration, a divided drug chamber configuration and a compact dual-drug configuration are described. The devices have features to prevent clogging of the dispensing catheter and the creation of a local vacuum caused by the dispensing of the drug fluid. Also provided are features of a failsafe refilling process, automatic refill notification, and performance verification process. The divided drug chamber configuration enables frequent or continuous minute doses. A dual-drug chamber configuration uses self-locking refill containers to prevent mismatching between refill containers and drug chambers.

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15-03-2012 дата публикации

Systems for isolation of a needle-based infusion set

Номер: US20120065587A1
Принадлежит: CR Bard Inc

A safety needle assembly of an infusion set for infusing fluids into a subcutaneously implanted access port is disclosed. The needle assembly is configured to prevent fluid/vapor escape therefrom so as to reduce or prevent fluid exposure to a clinician using the needle assembly. In one embodiment, the needle assembly comprises a handle portion including a needle extending therefrom, the needle defining a lumen for passage of a fluid therethrough. The needle assembly also includes a safety assembly defining a needle hole through which the needle initially extends. The safety assembly is selectively and axially slidable along the needle in order to shield a distal tip of the needle and prevent user contact therewith. A fluid isolation component is included in the safety assembly for isolating fluid escape from the needle to prevent exposure to a clinician.

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29-03-2012 дата публикации

Medical fluid injection system

Номер: US20120078091A1
Принадлежит: ACIST Medical Systems Inc

One implementation provides a method to provide injection procedure information in an injection system. In this implementation, the method includes displaying a plurality of different injection procedure options in a user interface of said system, wherein said plurality of different injection procedure options including a cardiac procedure option and a non-cardiac procedure option. The method further includes receiving a user selection of an injection procedure from said displayed plurality of difference injection procedure options, processing a default set of injection parameters based upon said selected injection procedure, and displaying said default set of injection parameters within the user interface of the system prior to an injection.

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12-04-2012 дата публикации

Methods for distributing agents to areas of brain

Номер: US20120087869A1
Принадлежит: MEDTRONIC INC

Broad cerebrospinal fluid (CSF) distribution of an agent is achievable by delivering the agent in a liquid formulation to the CSF at flow rates less than 500 microliters per hour, such as between about 2 microliters per hour and about 100 microliters per hour.

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19-04-2012 дата публикации

Methods and Apparatus for Translating a Continuous-Delivery Delivery Profile Into a Plurality of Periodic Bolus Deliveries

Номер: US20120095436A1
Принадлежит: Individual

Methods and apparatus for translating a continuous-delivery delivery profile into a plurality of periodic bolus deliveries.

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26-04-2012 дата публикации

Methods and systems for dosing a medicament

Номер: US20120101451A1
Принадлежит: Cequr SA

A manually actuated pump, such as a bolus delivery circuit of an insulin pump, combines a direct drive piston system with a lost motion valve system, to deliver reliably a full bolus dose, while precluding partial dosing or inadvertent overdosing conditions. The pump may also include a signaling device to indicate when a full bolus dose is delivered.

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03-05-2012 дата публикации

Thermal flow sensor integrated circuit with low response time and high sensitivity

Номер: US20120103085A1
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS NV

A thermal flow sensor integrated circuit for sensing flow in a channel based on temperature measurements, the integrated circuit having a temperature sensing element ( 30 ) on a front side of the integrated circuit arranged to face the channel, and a bond pad ( 60, 200 ) coupled electrically to the temperature sensing element, for making electrical contact off the integrated circuit, the bond pad being arranged to face away from the channel. By having the bond pad facing away from the channel, the space needed for the bond pad and any connections to it need not extend beyond the temperature sensing element and get in the way of the channel. Hence the temperature sensing element can be located closer to the channel or in the channel to enable measurements with better response time and sensitivity.

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03-05-2012 дата публикации

Operating A Portable Medical Device

Номер: US20120109100A1
Принадлежит: Asante Solutions Inc

Some embodiments of a portable medical device, such as an infusion pump, can receive an external reference signal (e.g., a radio, cellular and/or satellite signal) to provide an automatic time-setting and maintenance operation. In these circumstances, the medical device can maintain accurate time and date information even in the event of a power interruption, a time-zone change and/or an internal clock error, for example. In this manner, the portable medical device provides safe operation and added convenience to the user.

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10-05-2012 дата публикации

Methods and Apparatuses for Detecting Medical Device Acceleration, Temperature, and Humidity Conditions

Номер: US20120116197A1
Принадлежит: Medtronic Minimed Inc

An ambulatory medical device for detecting acceleration, temperature, and/or humidity conditions in or around the medical device is provided. The medical device includes one or more acceleration, thermal, and/or humidity sensors which detect acceleration, temperature, and/or humidity conditions in or around the medical device. In response to detected conditions, the medical device may, among other things, alter the operation of the device, provide an alarm or warning to the user, or transmit data about the detected conditions to another device.

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07-06-2012 дата публикации

Infusion pump flow balancing and synchronization system

Номер: US20120143116A1

A renal failure therapy system includes a blood pump, a dialysis fluid pump, a filtrate pump, at least one infusion pump, and a control unit configured to synchronize operation of the infusion pump to the blood pump or the filtrate pump.

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14-06-2012 дата публикации

Adhesive and peripheral systems and methods for medical devices

Номер: US20120150115A1
Принадлежит: Deka Products LP

Fill stations and base stations are provided for personal pump systems. The fill stations may be opened and closed to accept a reservoir and to allow fluid to be introduced into the reservoir for use with personal pump systems. The fill stations may hold the reservoir at a tilt relative to an underlying surface and may discourage overfilling of the reservoir. The filling stations may also include viewing windows having fluid lines marked thereon for indicating volume of fluid within the reservoir.

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28-06-2012 дата публикации

Monitoring the operating health of a force sensor in a fluid infusion device

Номер: US20120165780A1
Принадлежит: Medtronic Minimed Inc

A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, a force sensor, and an electronics module. The drive motor assembly regulates delivery of fluid by actuating a piston of a fluid reservoir, and the force sensor generates output levels in response to force imparted thereto during, for example, fluid delivery operations. The electronics module processes the output levels of the force sensor to assess the operating health of the force sensor, to check for occlusions in the fluid delivery path, and to monitor the seating status of the fluid reservoir.

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12-07-2012 дата публикации

Imaging-guided joint injection system

Номер: US20120179036A1
Принадлежит: Carticept Medical Inc

Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

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26-07-2012 дата публикации

Infusion Apparatuses and Methods of Use

Номер: US20120191071A1
Принадлежит: CR Bard Inc

An exemplary infusion system for accessing an implanted device is disclosed comprising an insertion assembly, a hub comprising a sealable path configured to receive at least a portion of the insertion assembly, a flexible catheter attached to the hub and configured to receive at least a portion of the insertion assembly, and an extension tube attached to the hub. The hub may comprise a manifold element configured to provide fluid communication between the flexible catheter and the extension tube. The hub may also comprise a septum configured to seal the sealable path upon removal of the insertion assembly from the flexible catheter. The extension tube may also be configured to receive at least a portion of the insertion assembly. Exemplary methods of providing a fluid communication path to an implanted device are also disclosed.

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02-08-2012 дата публикации

Drug Delivery Device

Номер: US20120197195A1
Принадлежит: Sanofi Aventis Deutschland GmbH

A drug delivery device ( 1 ), comprising a flexible container ( 9 ) for holding a drug ( 18 ) and an electrically activatable deformable squeezing member ( 8 ). The flexible container ( 9 ) comprises a container outlet ( 17 ) for dispensing a dose of the drug ( 18 ) from the flexible container ( 9 ). The squeezing member ( 8 ) is activatable for dispensing the dose of the drug ( 18 ). When activated, the squeezing member ( 8 ) is arranged and configured to squeeze the flexible container ( 9 ), thereby expelling the dose of the drug ( 18 ) from the flexible container ( 9 ) through the container outlet ( 17 ).

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09-08-2012 дата публикации

Coupling Devices And Kits Thereof

Номер: US20120203194A1
Принадлежит: Carmel Pharma AB

A coupling device for transferring substances, in particular medical substances, is disclosed. The coupling device can be used for transferring medical substances between a patient and an infusion bag containing the medical substances. In one or more embodiments, the coupling device may include a piercing member for connection to a medical device such as the infusion bag. A piercing member for a coupling device is also disclosed.

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16-08-2012 дата публикации

Patch-sized fluid delivery systems and methods

Номер: US20120209179A1
Принадлежит: Deka Products LP

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

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16-08-2012 дата публикации

Adhesive and peripheral systems and methods for medical devices

Номер: US20120209207A1
Автор: Eric Yeaton, Larry B. Gray
Принадлежит: Deka Products LP

A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

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16-08-2012 дата публикации

Resetting mechanism for a drug delivery device

Номер: US20120209211A1
Принадлежит: Sanofi Aventis Deutschland GmbH

A resettable dose setting mechanism for a drug delivery device comprising a driver for driving a spindle of the drug delivery device is provided. Said driver comprises a first component and a second component rotationally coupled to said first component. During resetting of said drug delivery device, said first component is rotationally decoupled from said second component.

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23-08-2012 дата публикации

Methods and apparatuses for detecting occlusions in an ambulatory infusion pump

Номер: US20120215169A1
Принадлежит: Medtronic Minimed Inc

An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. Methods, systems, and articles of manufacture for automatically detecting an occlusion in a medication infusion pump are provided. The electrical current to an infusion pump may be measured. Based on measurements of one or more variables, such as force, the infusion pump detects whether there is an occlusion in the system. The methods of detecting occlusions may be dynamic.

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23-08-2012 дата публикации

Pressure vented fluid reservoir for a fluid infusion device

Номер: US20120215177A1
Принадлежит: Medtronic Minimed Inc

Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.

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06-09-2012 дата публикации

Systems and methods for monitoring the use of medications

Номер: US20120226446A1
Принадлежит: Becton Dickinson and Co

Systems and methods for monitoring the use of a fluid over the lifecycle of the fluid, said systems including a plurality of fluid identification stations, each station having one or more sensors to detect and identify a parameter of a fluid, wherein a each station is operably interconnected thereby permitting each station to access and verify the identity of a fluid as determined by each independent fluid identification station.

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06-09-2012 дата публикации

Smart medication waste disposal

Номер: US20120226447A1
Принадлежит: Becton Dickinson and Co

A system for recording the wasting of fluids includes a waste disposal unit and a sensor system, having a sensor. The sensor can have one or more sensor elements in fluid communication with a fluid as it is wasted from a container into the waste disposal unit. The sensor system is configured to identify one or more drugs within the fluid and record the identity of the one or more drugs in a computer-readable medium electrically coupled to the sensor system.

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13-09-2012 дата публикации

Non-invasive radio frequency liquid level and volume detection system using phase shift

Номер: US20120227484A1

A medical fluid system includes a medical fluid pump; a container holding a fluid to be pumped by the medical fluid pump, the fluid at a first time having a first conductivity, the fluid at a second time having a second conductivity; and a radio frequency level sensor positioned in operable relation with the container, the radio frequency operation of the level sensor configured so as to be (i) indicative of a level of the fluid in the container and (ii) at least substantially independent of whether the fluid has the first conductivity or the second conductivity. The medical fluid system can determine the level of medical fluid by measuring the resistance, impedance or phase shift seen by the sensor.

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13-09-2012 дата публикации

Bodily fluid composition analyzer with disposable cassette

Номер: US20120232362A1
Принадлежит: Optiscan Biomedical Corp

Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.

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20-09-2012 дата публикации

Automated catheter length determination for implantable fluid delivery device

Номер: US20120238949A1
Автор: Scott L. Kalpin
Принадлежит: MEDTRONIC INC

Disclosed are methods and systems for automatically estimating the length of an implantable catheter by measuring the pressure decay response to pumping fluid through the catheter. The decay time for a unit fluid pressure pulse generated within the catheter is proportional to the catheter length, i.e. as the catheter length increases so does the decay time. The catheter length can therefore be estimated based on, e.g., the decay time of the pressure pulse. The estimated catheter length can also be analyzed to determine if it is representative of the actual catheter length, or, e.g., is affected by one or more catheter malfunctions including cuts and occlusions. Systems for automatically estimating the catheter length include an implantable catheter, a pumping mechanism, a pressure sensor configured to measure pressure within the catheter, and a processor that calculates the catheter length from a pressure pulse measured while delivering fluid through the catheter.

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20-09-2012 дата публикации

Drug Delivery Method Via Brain Extracellular Space and a Device Thereof

Номер: US20120239000A1
Автор: Hongbin Han
Принадлежит: Individual

The present invention relates to a method for drug delivery via brain extracellular space (ECS). It includes putting head of patient in an imaging apparatus; generating dynamic images of the brain via the imaging apparatus; delivering drugs into brain ECS of the patient according to the dynamic images and the drugs get to the therapeutic target by simple diffusion along concentration gradient. The present invention also relates to a device for drug delivery via brain ECS. Basing on the self-diffusion delivery (SDD) of drugs in brain ECS, the present invention can deliver drug into the ECS of the brain's relatively safe area in low speed, with small amounts of doses and without extra stress. Therefore, the present invention can reduce delivery time and dose of drugs, relieve injection pressure, decrease damages on normal brain tissue, and reduce the cost of treatment observably.

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11-10-2012 дата публикации

Goal-directed fluid therapy

Номер: US20120259308A1
Автор: Howard Levin, Mark Gelfand
Принадлежит: Individual

A method includes setting a hydration goal and administering a diuretic to the patient to induce increased urine flow and collecting urine expelled by the patient. The amount of urine expelled by the patient is determined based on the collected urine. The patient is infused with fluid from a fluid source. The amount of fluid infused into the patient is determined. Diuresis is induced by automatically and continuously adjusting the amount of fluid infused into the patient from the fluid source to meet the hydration goal based on the set hydration goal, the determined amount of urine expelled by the patient and the fluid infused.

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18-10-2012 дата публикации

Microfluidic device and method of use

Номер: US20120260718A1
Принадлежит: Integrated Sensing Systems Inc

A microfluidic device and sensing method that utilize a resonating tube configured to have sufficient sensitivity to be capable of sensing the volume of a gas present as bubbles in a liquid or the flow rate and/or density of a gas or gas mixture flowing through the tube. The tube has a freestanding tube portion supported above a surface of a substrate so as to be capable of vibrating in a plane normal to the surface of the substrate. As a gas-containing fluid flows through an internal passage of the tube, a drive signal vibrates the freestanding tube portion at a resonant frequency thereof. Coriolis-induced deflections of the freestanding tube portion are sensed relative to the substrate to produce an output corresponding to the sensed deflections, and the drive signal and/or the output are assessed to determine the volume, density and/or flow rate of the gas of the gas-containing fluid.

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18-10-2012 дата публикации

Advanced analyte sensor calibration and error detection

Номер: US20120265037A1
Принадлежит: Dexcom Inc

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

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25-10-2012 дата публикации

Arrangement for determining a longitudinal position of a stopper

Номер: US20120268741A1
Принадлежит: Sanofi Aventis Deutschland GmbH

The invention refers to an arrangement and a method for determining a longitudinal position of a stopper for sealing a compartment of a translucent medicament container for a liquid medicament (M). The arrangement comprises a circular light source and a photo sensitive sensor, wherein either the light source or the sensor is laterally arrangeable next to the medicament container extending over at least part of the length of the medicament container, and wherein the respective other of the light source and the sensor is arrangeable in a circular manner around a head of the medicament container. The light source is arranged to emit light into the medicament container. The light is scattered by the medicament or medicament container and detected by the sensor. The sensor is connected to a processor unit for detecting the position of the stopper).

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25-10-2012 дата публикации

Medical fluid autoconnection and autoidentification method

Номер: US20120271273A1

A medical fluid autoconnection method includes: enabling acceptance a pierceable connector that is capable of fluidly communicating with a source of medical fluid into a moveable holder; temporarily fixing a spike to a medical fluid pumping machine; automatically detecting whether the pierceable connector has been placed into the moveable holder; if the pierceable connector is sensed as being placed in the moveable holder, moving the holder so that the spike pierces the pierceable connector; and enabling medical fluid to be pumped from the source through the connected spiked and connector.

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01-11-2012 дата публикации

Systems for intravenous drug monitoring

Номер: US20120277612A1
Автор: Bo Li
Принадлежит: General Electric Co

A system for monitoring a concentration of an anesthetic drug using a patient's breath is provided. The system comprises a sampling subsystem for processing the patient's breath to form a breath sample, one or more sensors to measure drug concentration in the breath sample, one or more sensors to measure a concentration of gases in the breath sample; and one or more microprocessors for determining a concentration of the drug in a plasma of the patient using a transfer function and the concentration of the drug in the breath sample. A system for monitoring propofol concentration in patient's breath sample is also provided.

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08-11-2012 дата публикации

Powerhead of a Power Injection System

Номер: US20120283561A1
Принадлежит: Individual

A contrast media injection system includes detects the absolute position of the syringe ram using a non-contact sensor. A series of magnets and Hall-Effect sensors may be used or an opto-reflective system. Illuminated knobs that are connected to the drive mechanism for the syringe ram rotate with the drive and provide visual feedback on operation through the illumination. Analog Hall-Effect sensors are used to determine the presence or absence of magnets that identify the type of faceplate being used. The faceplates include control electronics, connected to the powerhead through connectors, which may be interchangeably used by the two faceplates. The faceplate electronics include detectors for automatically detecting the capacity of pre-filled syringes. Additional features include using historical data to provide optimum pressure limit values during an injection protocol, a removable memory device for storing and transferring information such as injection protocols and injector statistics, and password protection of such protocols.

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13-12-2012 дата публикации

Micromechanic passive flow regulator

Номер: US20120316492A1
Автор: Eric Chappel
Принадлежит: Debiotech SA

The invention concerns a flow regulator, made of a stack of 3 plates, respectively a top plate including a flexible membrane ( 1 ), a middle plate ( 2 ) with pillars and through holes and a bottom plate ( 3 ) with fluidic ports, micro channels and through holes ( 8,9,12 ). The principle is based on the deformation of the membrane due to the pressure of the liquid. The membrane goes in contact with the pillars of the middle plate, obstructing gradually the through holes of the pillars. The device is designed to keep the flow constant in a predefined range of pressure. The device is dedicated to ultra low flow rate up to 1 ml per day or below, typically for drug infusion. Plastic flow regulators comprise preferably several independent valves coupled in parallel. The membrane plate is therefore made of several flexible membranes obstructing gradually the flow by increasing the pressure. Stress limiters are used to avoid plastic deformation of the membrane. For implanted pump, the use of a flow regulator instead of a flow restrictor has several advantages, including the possibility to reduce significantly the reservoir pressure and to generate directly the pressure during the pump filling by using an elastic drug reservoir.

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13-12-2012 дата публикации

Intravenous fluid monitoring device

Номер: US20120316498A1
Принадлежит: US Department of Navy

A device for automatic monitoring intravenous fluid flow rate and temperature. The inventive device is capable of automatically adjusting the temperature of the fluid administered to a patient and recording the fluid flow rate and temperature. The device is also capable of transferring data to an electronic data storage repository via a wire connection or wirelessly.

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20-12-2012 дата публикации

Valves, Valved Fluid Transfer Devices and Ambulatory Infusion Devices Including the same

Номер: US20120323179A1
Принадлежит: Individual

Valves, valved fluid transfer devices and ambulatory infusion devices including the same.

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20-12-2012 дата публикации

Applying shear stress for disease treatment

Номер: US20120323223A1
Принадлежит: HRD Corp

A system for applying shear stress ex-situ to a fluid. A method of preparing a fluid for intravenous administration to a patient. In some embodiments, the system comprises a shear device; and at least one device configured for intravenous administration of the fluid to a patient, the devices defining a fluid passage configured to be sterilized and maintained sterile during use, the fluid comprising at least one therapeutic fluid, blood, or a combination thereof. The shear device of the system is in fluid communication with the at least one device configured for intravenous administration of the fluid to a patient.

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27-12-2012 дата публикации

Selectively Controlling Fluid Flow Through a Fluid Pathway

Номер: US20120325330A1
Принадлежит: Crisi Medical Systems Inc

Systems and methods for controlling fluid delivery via a manually administrable medication container to a patient through a fluid delivery pathway are provided. The systems and methods described herein incorporate rules-based clinical decision support logic to drive a flow control valve within a flow pathway to determine whether the IV fluid connected to the input port is consistent with medical orders, accepted delivery protocols, and/or specific patient and patient histories. Related apparatus, systems, methods and articles are also described.

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27-12-2012 дата публикации

Medicament infusion systems

Номер: US20120330238A1
Принадлежит: Smiths Medical ASD Inc

A drug delivery system has a fluid store that has a first tubing having an outlet fitted with a connector of a given configuration that prevents the connector from being coupled to a conventional counterpart connector. The system further has a tube retaining device that has a catheter extending out of one of its ends and an inlet connector at its other end that has a configuration complementary to the configuration of the outlet connector of the first tubing, so that the first tubing may be matingly connected to the tube retaining device to establish a through fluid path from the first tubing to the catheter. A one-way valve may be provided to the tubing to prevent fluid from flowing backwards into the tubing. The tubing can be selectively occluded and opened to regulate the flow of fluid from the tubing to the catheter.

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10-01-2013 дата публикации

Connector for a container including a medicinal active ingredient

Номер: US20130008561A1
Принадлежит: FRESENIUS KABI DEUTSCHLAND GmbH

The invention relates to a connector for containers containing medicinal active ingredient, which connector makes it possible to transfer active ingredient from one container into another container. The connector ( 1, 1 ′) according to the invention comprises a first connection region ( 3, 3 ′) for the connection of a first container ( 2, 2 ′), a guide element ( 4, 4 ′), a piercing element ( 5, 5 ′) and a partition wall ( 6 ), wherein the guide element ( 4, 4 ′) has a duct ( 7 ) designed for transferring a medicinal active ingredient, the piercing element ( 5, 5 ′) is arranged, at least in certain sections, in the duct ( 7 ) and is axially movably guided within the duct ( 7 ) by the guide element ( 4, 4 ′), and, by connecting a container ( 2, 2 ′) in the first connection region ( 3, 3 ′), the piercing element ( 5, 5 ′) can be moved from a starting position, in which the piercing element ( 5, 5 ′) does not open the partition wall ( 6 ), into an end position, in which the piercing element ( 5, 5 ′) opens the partition wall ( 6 ) in order to transfer a medicinal active ingredient.

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10-01-2013 дата публикации

Software features for medical infusion pump

Номер: US20130012879A1
Принадлежит: Individual

Various software features useable in a medical infusion pump are disclosed. In certain aspects, localized alarm and message handling systems are disclosed. In other aspects, variable intensity alarms are disclosed. In further aspects, cost tracking systems and methods for medical infusion pumps are disclosed. In still further aspects, methods and systems implementing a variable delay of pressure decay in a medical infusion pump are disclosed. In other aspects, methods and systems implementing a timed intermittent bolus by pressure are disclosed.

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17-01-2013 дата публикации

Micropump

Номер: US20130017099A1
Принадлежит: SENSILE PAT AG

A pump comprising a housing comprising a rotor chamber, inlet and outlet channels opening into the rotor chamber, and inlet and outlet seals mounted on a surface of the chamber, and a rotor rotatably and axially slidably received in the chamber and comprising a first axial extension comprising a liquid supply channel and a second axial extension comprising a liquid supply channel, the first and second axial extensions having different diameters. The inlet and outlet seals engage a surface of the rotor, whereby the liquid supply channel of each axial extension in conjunction with a corresponding seal forms a valve that opens and closes as a function of the angular and axial displacement of the rotor. At least one of the inlet and outlet channels opens transversely into the rotor chamber and at least one of the inlet and outlet seals forms a closed circuit circumscribing said at least one of the inlet and outlet channels.

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24-01-2013 дата публикации

Patient-controlled analgesia safety system

Номер: US20130023820A1
Принадлежит: Individual

The patient-controlled analgesia (PCA) safety system includes a housing with a hollow compartment. A display and keypad are disposed on one side of the for display of monitoring data and selective commands respectively. An analgesic module and an antidote module are detachably mounted inside the compartment. A control module is disposed inside the housing. A vital signs monitor is connected to the control module to monitor a patient. In the event of abnormal readings due to, e.g., overdose or drug-related complications, the control module can automatically administer an antidote to the analgesia. The control module can also alert a nurse monitor and/or other personnel wirelessly to insure someone is notified of the potential emergency. The PCA safety system can also be provided in a separate safety module having a detachably mounted antidote module.

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24-01-2013 дата публикации

Needle guard

Номер: US20130023835A1
Принадлежит: Injectimed Inc

A needle guard assembly having a resilient arm extending from a base situated to slide along the shaft of a needle. In one implementation the needle guard has an elongate containment member that rides with the resilient arm and is co-operable with the resilient arm to effectuate a covering of the entire distal tip of the needle upon the needle being retracted into the needle guard.

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31-01-2013 дата публикации

Medical fluid injector device

Номер: US20130030290A1
Автор: Shigeru Nemoto
Принадлежит: Nemoto Kyorindo Co Ltd

A medical fluid injector device injecting a patient with a mixed medical fluid provided by a plurality of medical fluids and capable of simply setting injection conditions for the mixed medical fluid. A medical fluid injector ( 100 ) includes an injector head ( 110 ) injecting a diluted contrast medium into a patient and a controller unit ( 50 ). The controller unit ( 50 ) performs a process of receiving an input relating to an injection rate of the diluted medical fluid, a process of receiving an input relating to a mixture ratio by an operator, a process of calculating an injection rate of a contrast medium based on the mixture ratio, and a process of calculating an injection rate of physiological saline based on the mixture ratio. The injector head ( 110 ) injects the contrast medium and the physiological saline at the calculated injection rate of the contrast medium and the calculated injection rate of the physiological saline, respectively.

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07-02-2013 дата публикации

Multidirectional microfluidic drug delivery devices with conformable balloons

Номер: US20130035660A1
Автор: Pj ANAND
Принадлежит: Alcyone Lifesciences Inc

The methods, systems, and devices disclosed herein generally involve convection-enhanced delivery of drugs to a target region within a patient. Microfluidic catheter devices are disclosed that are particularly suitable for targeted delivery of drugs via convection, including devices capable of multi-directional drug delivery, devices that control fluid pressure and velocity using the venturi effect, and devices that include conformable balloons. Methods of treating various diseases using such devices are also disclosed, including methods of treating cerebral and spinal cavernous malformations, cavernomas, and hemangiomas, methods of treating neurological diseases, methods of treatment using multiple microfluidic delivery devices, methods of treating hearing disorders, methods of spinal drug delivery using microfluidic devices, and methods of delivering stem cells and therapeutics during fetal surgery. Methods of manufacturing such devices are also disclosed.

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21-02-2013 дата публикации

Device and method for determining the fill level of a flexible medicine reservoir

Номер: US20130042678A1
Автор: Gérald Studer
Принадлежит: ROCHE DIAGNOSTICS INTERNATIONAL AG

Included are systems and methods for determining a fill level of an inflow-less flexible medicine reservoir as a source for medicine, where the inflow-less flexible medicine reservoir has a monotonically decreasing fill level. Some embodiments of a device include a stop surface designed and arranged such that the stop surface contacts the inflow-less flexible medicine reservoir while the inflow-less flexible medicine reservoir is filled above a predetermined level. Similarly, some embodiments of the device additionally include a release detector that generates an output signal indicative of contact between the stop surface and the inflow-less flexible medicine reservoir being released and a processing unit for determining the fill level of the inflow-less flexible medicine reservoir from an output signal of the release detector.

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21-02-2013 дата публикации

Intelligent alarms

Номер: US20130046158A1
Автор: Joe Bisera, Wanchun Tang

A patient in intensive care is monitored by connecting the outputs of a plurality of sensors to a computer, where the sensors all relate to one mode of functioning such as heart beating, respiration, infusion of a liquid into the patient, etc. The sensor outputs are delivered to a computer that sounds an alarm, only if all sensors that indicate one function (e.g. heart beating) indicate dangerously low operation of that function. This avoids many false alarms caused by one sensor having a low output such as due to accidental disconnection of a wire.

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07-03-2013 дата публикации

System and method for joint integrity detection

Номер: US20130056130A1
Принадлежит: CareFusion 303 Inc

An inspectable joint in a medical device is disclosed that includes at least one medical-grade tube having an end, a medical-grade fitting having at least one joining surface configured to accept the end of the tube, and a joining material disposed between the tube and the joining surface. The joining material includes a first component configured to couple the tube to the fitting and a second component configured to provide observable evidence of the presence of the joining material between the tube and the joining surface.

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07-03-2013 дата публикации

Liquid medicine administering device for endoscopic surgery, medical controller for liquid medicine, and liquid medicine administering device for endoscopic surgery comprising same

Номер: US20130060193A1
Автор: Sang Yub Lee
Принадлежит: Individual

Disclosed are a medical controller for liquid medicine, and a liquid medicine administering device for endoscopic surgery comprising same. The liquid medicine administering device for endoscopic surgery comprises: a head member including at least one liquid medicine entrance port through which liquid medicine from a syringe is admitted, and a first gas entrance port into which gas enters from a gas supply line and which is connected to the liquid medicine entrance port; a strong member connected to the head member, and including a liquid medicine passage inserted into a human body for discharging the liquid medicine to a surgical site; and a valve unit installed on the head member to selectively communicate the liquid medicine passage with the liquid medicine entrance port or the first gas entrance port. The liquid medicine that enters through the liquid medicine entrance port is through the liquid medicine passage by means of air provided from the first as entrance port and is discharged to the surgical site.

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14-03-2013 дата публикации

Medical fluid injection system

Номер: US20130066202A1
Принадлежит: ACIST Medical Systems Inc

One embodiment provides a method of using contextual lighting to assist a user of a medical fluid injection system. In this embodiment, the method includes providing a lighted display in proximity to a component of the injection system during setup of the medical fluid injection system. If the user has properly performed a setup function that is associated with the component of the injection system, the method further comprises providing a first visual indication on the lighted display. If the user has not properly performed the setup function that is associated with the component of the injection system, the method further comprises providing a second visual indication on the lighted display.

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14-03-2013 дата публикации

Sterile fluid pathway connection to drug containers for drug delivery pumps

Номер: US20130066274A1
Принадлежит: UNITRACT SYRINGE PTY LTD

A user-initiated fluid pathway connection includes: a connection hub, a piercing member, a sterile sleeve, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the piercing member is initially retained within the sterile sleeve between the connection hub and the pierceable seal of the drug container. The connection hub may include an internal aperture within the connection hub which functions as a flow restrictor and wherein a piercing member is connected to one end of the internal aperture and a fluid conduit is connected to another end of the internal aperture. A drug delivery pump with integrated sterility maintenance features includes a housing, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection as described above, a power and control system, and a drive mechanism connected to a drug container are mounted. Methods of assembly and operation are also provided.

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14-03-2013 дата публикации

SEALING ASSEMBLY WITH PINCH VALVE STRUCTURE FOR A FLUID INFUSION DEVICE HAVING A NEEDLED FLUID RESERVOIR

Номер: US20130066281A1
Принадлежит: Medtronic Minimed, Inc.

A fluid infusion device that delivers medication fluid to a user includes a removable fluid reservoir having a reservoir port and a hollow fluid reservoir needle, a base plate having a reservoir port receptacle for the reservoir port and the reservoir needle, and an inlet structure in the reservoir port receptacle to define at least a portion of a fluid chamber. The fluid infusion device also includes a needle sealing element having a base section, an end section opposite the base section, a neck section between the base section and the end section, and a needle opening extending through the base section, the neck section, and the end section. A compression element is coupled around the neck section to impart an inward biasing force near the needle opening. 1. A sealing assembly for a fluid infusion device that cooperates with a fluid reservoir having a reservoir port and a hollow fluid reservoir needle at least partially located within the reservoir port , the sealing assembly comprising:a reservoir port receptacle to receive the reservoir port, and comprising a proximal end, a distal end extending from the proximal end, and a needle entry formed in the distal end to receive the hollow fluid reservoir needle;a fluid chamber located at least partially in the reservoir port receptacle; and a needle sealing element comprising a base section adjacent to the fluid chamber, an end section opposite the base section, a neck section between the base section and the end section, and a needle opening extending through the base section, the neck section, and the end section, wherein the needle opening accommodates the hollow fluid reservoir needle when the reservoir port engages the reservoir port receptacle; and', 'a compression element coupled around the neck section to impart an inward biasing force near the needle opening., 'a sealing component positioned in the reservoir port receptacle to cooperate with the fluid chamber, the sealing component comprising2. The sealing ...

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21-03-2013 дата публикации

Device having array provided with fine protrusions

Номер: US20130072874A1
Принадлежит: Hisamitsu Pharmaceutical Co Inc

An array 1 provided with microprotrusions comprises a base 2 and tapered microprotrusions 3 each disposed on the base 2 and tapering down toward the tip from the bottom. Letting a distance from the tip to the bottom on an arbitrary side of each microprotrusion 3 as a and letting the length of a second line segment prepared by projecting a first line segment representing the distance a onto the base 2 as b, a relationship of 1.0<(a/b)≦7.5 holds.

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04-04-2013 дата публикации

Flow regulator for infusion pump and method of manufacturing the same

Номер: US20130081726A1
Автор: Seik Oh
Принадлежит: Seik Oh

An ambulatory drug infusion system includes a disposable ambulatory infusion pump and a flow regulator for regulating flow of the drug supplied from the disposable ambulatory infusion pump. The flow regulator includes a cylinder assembly of first, second and third cylinders arranged coaxially. The flow regulator includes a continuous spiral liquid-flow channel formed between the first cylinder and the second cylinder fitted into the first cylinder. The regulator includes bypass through-holes in communication with the spiral channel and formed in the second cylinder. The regulator further includes liquid-flow passages formed between the second cylinder and the third cylinder fitted into the second cylinder. The through-holes are in communication with the passages, respectively. One of the passages can be selected to choose a predetermined flow rate. The regulator further includes a diaphragm valve which can regulate fluid communication between the spiral liquid-flow channel and an outlet.

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18-04-2013 дата публикации

IMPLANTABLE PUMP WITH RESERVOIR LEVEL DETECTOR

Номер: US20130096538A1
Принадлежит: Codman Neuro Sciences Sárl

An implantable pump includes a base plate and a can that are parts of the pump housing. The base plate bottom divides the housing into a first electronics chamber and a second chamber. A bellows mechanism is connected to the base plate and is disposed within the second chamber. The bellow mechanism has an expandable sidewall and a bottom plate. The bellow mechanism divides the second chamber into a medicament receiving portion and a non-medicament-receiving portion. The bellow mechanism has an intermediate plate disposed within the medicament-receiving portion. A coil is disposed in a recess on the lower surface of the base plate, and the coil is spaced from an internal wall of the recess. The amount of fluid remaining in the implantable pump can be monitored by energizing the coil. A primary magnetic field is generated by the energized coil. A secondary magnetic field, which is dependant on the position of the bottom and intermediate plate of the bellow mechanism, couples back to the primary field affecting the electrical characteristics of the coil. The amount of fluid remaining in the reservoir is determined based on the resulting changes in the electrical characteristics of the coil. 117-. (canceled)18. A method of monitoring the amount of fluid remaining in an implantable pump , the pump having a housing; a base plate connected to said housing , said base plate dividing said housing into an electronics chamber and a second chamber; a bellow mechanism connected to said base plate and disposed within said second chamber , said bellow mechanism having an expandable side wall and a bottom plate , said bellow mechanism dividing said second chamber into a medicament receiving portion and a non-medicament receiving portion , said bellow mechanism having a intermediate plate disposed within said medicament receiving portion; and a coil disposed on the lower surface of the base plate; the method comprising the steps of:energizing the coil such that a magnetic field is ...

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25-04-2013 дата публикации

SYSTEMS AND METHODS FOR PROVIDING A CLOSED VENTING HAZARDOUS DRUG IV SET

Номер: US20130102974A1
Принадлежит: BECTON, DICKINSON AND COMPANY

A device for priming and venting a hazardous drug within an intravenous administration set. The device includes various access ports and fluid channels to permit direct injection of a hazardous drug into the fluid reservoir, while eliminating the possibility of undesirable exposure to the hazardous drug. The device further includes priming and flushing ports to enable flushing of a hazardous drug from the system following an infusion procedure. 116.-. (canceled)17. A device for storing and administering a hazardous solution to a patient via an intravenous needle , the device comprising:a spike comprising a fluid pathway having an input and an output, the spike being configured to insert within a primary fluid reservoir such that the input of the first fluid pathway is in fluid communication with a fluid within the primary fluid reservoir; anda drip chamber fluidly coupled to the spike and comprising an input, an output, and a priming valve, the drip chamber input being fluidly coupled to the output of the fluid pathway, the priming valve being positioned on a portion of the drip chamber, and the output of the drip chamber being configured to receive a patient conduit.18. The device of claim 17 , further comprising a membrane interposedly disposed within the drip chamber between the priming valve and the output of the drip chamber claim 17 , wherein the membrane prevents passage of air from the drip chamber to the output of the drip chamber.19. The device of claim 17 , further comprising a priming solution inserted into the drip chamber via the priming valve.20. The device of claim 18 , wherein the membrane comprises at least one of polytetrafluoroethylene claim 18 , hydrophilic nylon claim 18 , hydrophilic polypropylene claim 18 , hydrophilic polyethersulfone claim 18 , and a nonwoven material having a hydrophilic coating. The present invention relates to systems and methods for priming an intravenous (IV) administration set with a hazardous drug or chemical, as ...

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09-05-2013 дата публикации

PERISTALTIC INFUSION PUMP WITH LOCKING MECHANISM

Номер: US20130116623A1
Автор: Goldor Ori, Rotem Shachar
Принадлежит: Q-CORE MEDICAL LTD.

A medical device includes an interface unit body, which is configured to hold a portion of a flexible infusion tube. A hinge insert is fixed to the interface unit body and is configured to engage a hinge receptacle, which defines a hinge axis, on an infusion pump. A catch insert is fixed to the interface unit body and is configured to lock onto a catch receptacle on the infusion pump upon rotation of the mechanical interface unit about the hinge axis while the hinge insert engages the hinge receptacle, so as to bring the tube into engagement with a peristaltic mechanism of the infusion pump in order to enable the peristaltic mechanism to propel a fluid through the tube. 121.-. (canceled)22. A interface unit body configured to be engaged to an infusion pump wherein the infusion pump includes a key , the interface unit body comprising:a housing to receive a tube; and (1) a safety default closed state to prevent flow of fluid through the tube when disengaged from the infusion pump,', '(2) a manually open state when disengaged from the infusion pump and', '(3) a default open state to allow controlled flow of fluid through the tube when engaged to the infusion pump,, 'an anti-free flow mechanism including at least three mechanical stateswherein said anti free flow mechanism is caused to transition to said safety default closed state upon disengagement of the interface unit body from the infusion pump by the key.23. The interface unit body of claim 22 , wherein said manually open state and said default open state are further configured to enable insertion of a flexible infusion tube.24. The interface unit body of claim 22 , further comprising a flexible infusion tube.25. The interface unit body of claim 22 , wherein said manually open state is further configured to enable free flow of fluid through the tube.26. The interface unit body of claim 22 , wherein said interface unit body is configured to allow fluid to propel through the tube by a peristaltic mechanism ...

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09-05-2013 дата публикации

LARGE-VOLUME BOLUS PATIENT CONTROLLED DRUG ADMINISTRATION DEVICE

Номер: US20130116630A1
Принадлежит: KIMBERLY-CLARK WORLDWIDE, INC.

A device for dispensing fluid to a patient enabling either or both of a continuous flow, as well as successive, large-volume boluses. A first reservoir provides a source of fluid under pressure. A bolus flow path provides for the delivery of a bolus dose of fluid and an optional continuous flow path provides a continuous flow rate of fluid. Both flow paths are in fluid communication with the source of fluid. A bolus delivery system in fluid communication with the bolus flow path receives fluid from the first reservoir, expands to pressurize fluid, stores the pressurized fluid, and dispenses the pressurized fluid while avoiding bolus refill until enabled to expand in a subsequent delivery cycle. An actuator releases fluid from the bolus delivery system such that when actuated by the patient, fluid is permitted to flow out of the bolus reservoir to the patient without further action by the patient. 1. A device for dispensing fluid to a patient comprising:a first reservoir configured to provide a source of fluid under pressure;a bolus flow path for the delivery of a bolus dose of fluid;a large volume bolus delivery system in fluid communication with the bolus flow path and configured to receive fluid from the first reservoir, the bolus delivery system being configured to elastically expand to pressurize fluid, store the pressurized fluid and dispense the pressurized fluid while avoiding bolus refill during bolus delivery or after bolus delivery but before it is enabled to elastically expand in a subsequent delivery cycle; anda patient operable actuator to release fluid from the bolus delivery system, the actuator being configured such that it does not require effort to force the fluid out of the bolus reservoir and that when actuated by the patient, fluid is permitted to flow out of the bolus reservoir to the patient without further action by the patient.2. The device of claim 1 , including a continuous flow path from the source providing a continuous and substantially ...

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09-05-2013 дата публикации

Method and System For The Safety, Analysis and Supervision of Insulin Pump Action and Other Modes of Insulin Delivery in Diabetes

Номер: US20130116649A1

An insulin delivery supervisor (IDS) with a safety analysis and supervision function that can reside between the insulin request and the insulin delivery and can intercept any excessive insulin requests before the insulin was delivered. The IDS can be implemented in any system based on insulin pump or pen and will work with either SMBG or CGM modes of blood glucose monitoring. 1. A method comprising judging the safety of insulin delivery in response to an insulin request , wherein the insulin request comprises a request for an amount of insulin.2. The method of further comprising delivering insulin when the insulin request is not excessive in view of a computation of either a blood glucose lowering effect or computing a relative insulin level claim 1 , wherein the insulin request is excessive claim 1 , if the requested amount of insulin will result in hypoglycemia unless additional action is taken at the time the insulin amount is delivered.3. The method of claim 2 , wherein the blood glucose lowering effect is calculated when recent blood glucose information is available.4. The method according to further comprising recommending gCHO when the insulin request is deemed excessive in view of the calculation.5. The method of claim 2 , wherein the relative insulin level is calculated when recent blood glucose information is not available.6. The method according to further comprising recommending a blood glucose measurement when the insulin request is deemed excessive in view of the calculation.7. The method according to further comprising seeking user confirmation when the insulin request is deemed excessive in view of the computation.8. A safety supervision module programmed to judge the safety of insulin delivery in response to an insulin request claim 2 , wherein the insulin request comprises a request for an amount of insulin.9. The safety supervision module of further programmed to control delivery of insulin in response to an insulin request when the insulin ...

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09-05-2013 дата публикации

Implantable drug pumps and refill devices therefor

Номер: US20130116664A1
Принадлежит: MiniPumps LLC

Implanted drug pump devices can be refilled via a fill port in the drug reservoir that includes a self-resealable septum.

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09-05-2013 дата публикации

IMPLANTABLE DRUG PUMPS AND REFILL DEVICES THEREFOR

Номер: US20130116665A1
Принадлежит: MINIPUMPS, LLC

Implanted drug pump devices can be refilled with a refill needle inserted through a fill port in the drug reservoir of the drug pump device. Proper needle insertion may be verified visually or using electrical, magnetic, optical, acoustic, or other suitable sensing mechanisms. 1. An implantable , refillable drug pump device comprising:a drug reservoir having a fill port for insertion of a needle through an aperture thereof; anda sensor for sensing needle insertion through the aperture, the sensor comprising an emitter and a detector establishing a signal path therebetween through the fill port, the emitter and detector being located such that, when the needle has been inserted, the signal path is detectably interrupted.2. The drug pump device of claim 1 , wherein the emitter and the detector are disposed in opposed relation about a side portion of the fill port claim 1 , the aperture being through a top of the fill port.3. The drug pump device of claim 1 , wherein the emitter is an optical emitter and the detector is an optical detector.4. The drug pump device of claim 3 , wherein the optical emitter emits visible light into the fill port.5. The drug pump device of claim 3 , wherein the emitter and the detector are disposed outside opposed optical windows through a wall of the fill port.6. The drug pump device of claim 3 , wherein the emitter and the detector are disposed outside and aimed through an optical window through a wall of the fill port claim 3 , the device further comprising an optical reflector disposed opposite the optical window so as to reflect claim 3 , to the detector claim 3 , light from the emitter passing through the fill port whereby claim 3 , when the needle has been inserted claim 3 , the signal path is detectably interrupted between the emitter and the reflector.7. The drug pump device of claim 1 , wherein the emitter is an acoustic emitter and the detector is an acoustic detector.8. An implantable claim 1 , refillable drug pump device ...

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09-05-2013 дата публикации

IMPLANTABLE DRUG PUMPS AND REFILL DEVICES THEREFOR

Номер: US20130116666A1
Автор: Caffey Sean, Shih Jason
Принадлежит: MINIPUMPS, LLC

A system for refilling the drug reservoir of an implanted drug pump device may facilitate wireless data exchange between the refill system and the implanted device, e.g., to verify proper drug selection prior to commencement of the refill process. 1. A system for filling an implanted , refillable drug pump device comprising a drug reservoir with a fill port , the system comprising:a needle for insertion into the fill port of the drug pump device, the needle being fluidically connectable to at least one fluid container;at least one pump for causing fluid flow through the needle between the at least one fluid container and the drug reservoir;electronic circuitry including a processor for controlling operation of the at least one pump; anda wireless communication module facilitating wireless data exchange between the electronic circuitry and the implanted drug pump device.2. The system of claim 1 , further comprising:tubing for fluidically connecting the at least one fluid container to the needle.3. The system of claim 1 , wherein the wireless communication module is integrated in the electronic circuitry.4. The system of claim 1 , wherein the wireless communication module is integrated in a handheld telemetry wand in communication with the electronic circuitry.5. The system of claim 1 , wherein the wireless communication module is integrated in patient-worn eyeglasses in communication with the electronic circuitry.6. The system of claim 1 , wherein the electronic circuitry is configured to control pump operation based claim 1 , at least in part claim 1 , on data received from the implanted drug pump device via the wireless communication module.7. The system of claim 6 , wherein the data comprises sensor readings of sensors disposed in the drug reservoir.8. The system of claim 6 , wherein the data comprises information indicative of a type of drug to be administered.9. The system of claim 6 , wherein the data comprises information indicative of an error condition that ...

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16-05-2013 дата публикации

Hemodynamic pressure sensor test system and method

Номер: US20130123619A1
Автор: Leon T. Griggs
Принадлежит: ACIST Medical Systems Inc

A pressure sensor suitable for use in a powered contrast injector system may be tested to help validate the operability and/or integrity of the sensor. In some examples, the pressure sensor may be tested by generating a pressure pulse in a fluid line fluidly connected to the pressure sensor so as to generate a first pressure reading. A high pressure fluid at a pressure above a maximum operating pressure of the pressure sensor may be conveyed through a valve fluidly connected to the pressure sensor. Subsequent to conveying the high pressure fluid through the valve, the pressure sensor may again be tested by generating a pressure pulse in the fluid line fluidly connected to the pressure sensor so as to generate a second pressure reading. In some examples, the first pressure reading is compared to the second pressure reading to determine whether the pressure sensor has passed or failed.

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16-05-2013 дата публикации

Device for sampling and reinjecting a fluid, and related injector and sampling kit

Номер: US20130123683A1
Автор: Eric Perouse
Принадлежит: SYMATESE

A device includes a hollow body delimiting a cavity for receiving the fluid, which cavity opens in a proximal opening and at least one distal opening for sampling and/or reinjection and a piston movably mounted in the receiving cavity to obturate the proximal opening. The device includes an assembly for selective distribution of a proximal part of the fluid located in the receiving cavity, including a fluid circulation channel that passes through the piston, which channel opens into the receiving cavity. The circulation channel and/or a distribution channel is able to cooperate or to communicate with an additional flow regulation device which can be manually actionable.

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16-05-2013 дата публикации

WEARABLE INFUSION DEVICE AND SYSTEM

Номер: US20130123709A1
Принадлежит: CALIBRA MEDICAL, INC.

Disclosed is a drug infusion system comprising a drug infusion device having a reservoir, a window for viewing the contents of the reservoir, a cannula arranged to be deployed beneath the skin of a patient, and an actuator configured to be manually actuated to drive a medicament from the reservoir to the cannula. The system also has a cannula cover and a needle handle that holds a needle for insertion into the patient. The cannula cover and needle handle are detachably attached to the drug infusion device, and each is attachable to the other. The device further comprises a septum and a septum pincher to seal the device. The device also comprises a pumping mechanism, part of which are a last-dose lock-out mechanism and an occlusion detection mechanism, both of which operate on the same actuator. 1. A drug infusion system comprising:a skin-adherable drug infusion device comprising a reservoir within the device, a cannula having an end portion to be deployed beneath the skin of a patient, and an actuator configured to be manually actuated to drive a medicament from the reservoir to the cannula;a cannula cover that covers the end portion of the cannula arranged to be deployed beneath the skin of the patient; anda needle handle, wherein the needle handle holds a needle for insertion into the patient.2. The system of claim 1 , wherein the cannula cover is configured to be detachably attached to the drug infusion device.3. The system of claim 1 , wherein the needle handle is configured to be detachably attached to the drug infusion device.4. The system of claim 1 , wherein the needle handle is configured to be coupled to the cannula cover.5. The system of claim 1 , wherein the cannula cover includes a cavity for receiving the needle when the needle handle is coupled to the cannula cover.6. The system of claim 1 , wherein the device includes an adhesive layer for adhering to the skin of a user and a removable cover overlying the adhesive layer and wherein the cannula cover ...

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16-05-2013 дата публикации

INJECTION SITE FOR MALE LUER OR OTHER TUBULAR CONNECTOR

Номер: US20130123713A1
Принадлежит: NXSTAGE MEDICAL, INC.

A medical device has an interior for containment of fluids; an opening into the interior, an elastomeric wall comprising a fixedly placed, flexible barrier across the opening; and a retention wall positioned adjacent to a peripheral portion of the elastomeric wall. The retention wall defines a central opening and has a generally rigid retention zone surrounding the central opening, to engage and retain a connector tube which is advanced into the central opening to open a flow aperture through the elastomeric wall, for flow through the wall and connector tube. One of the retention zone and connector tube may be made of a material of sufficient hardness that material of the other engaging member is deformed by engagement therewith, which increases the strength of retention between the retention wall and the connector tube. 1. A medical device comprising:an interior for containment of fluids;an opening into the interior;an elastomeric wall having a fixedly placed, flexible barrier across said opening; anda retention wall positioned adjacent to a peripheral portion of said elastomeric wall,wherein said retention wall defines a central opening,said retention wall has a generally rigid retention zone surrounding said central opening and is configured to engage and to retain a connector tube, which has a leading end that is advanced into said central opening to displace said elastomeric wall so as to weaken the resistance to flow of a closed perforation extending substantially through said elastomeric wall,said retention zone is sized to engage and to hold said connector tube before said leading end has completely penetrated said elastomeric wall, whereby the perforation of said elastomeric wall remains sealed but can be opened for fluid flow by application of a low pressure differential in one direction to cause fluid flow through the perforation of said elastomeric wall, andsaid elastomeric wall exhibits a substantially higher resistance to said fluid flow under pressure ...

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16-05-2013 дата публикации

INFUSION PUMP INCLUDING PAIN CONTROLLED ANALGESIC ("PCA") APPARATUS

Номер: US20130123745A1
Автор: Simmons Mark Randal
Принадлежит:

An infusion pump includes: a housing, a pump actuator supported by the housing, electronics configured to control the pump actuator, a pain controlled analgesic (“PCA”) input device, a cord having a remote end connected to the PCA input device and a local end connected to the housing, a remote integrated circuit; and a local integrated circuit in communication with the electronics and the remote integrated circuit so as to provide operational information concerning the PCA input device to the electronics. 1. An infusion pump method comprising:providing a pain controlled analgesic device having a remote controller;operably coupling an infusion pump actuator to a local controller;attempting to send an electrical signal from one of the local controller and the remote controller to the other of the local controller and the remote controller;attempting to receive the sent electrical signal at the other of the local controller and the remote controller; andif the other of the local controller and remote controller does not receive the sent electrical signal, sending an output that is indicative of a frayed cord or an open circuit condition between the remote controller and the local controller.2. The infusion pump method of claim 1 , which includes attempting to send the electrical signal from the local controller to the remote controller.3. The infusion pump method of claim 1 , which includes periodically attempting to send the electrical signal from the local controller or the remote controller.4. The infusion pump method of claim 1 , which includes if the other of the local and the remote controller receives the sent electrical signal claim 1 , waiting a predetermined amount of time and repeating the attempting and output sending steps.5. The infusion pump method of claim 1 , which includes issuing an alert in response to the output indicative of the frayed cord or the open circuit condition.6. The infusion pump method of claim 1 , which includes indicating (i) audibly ...

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23-05-2013 дата публикации

Medical device receptacle filling method and apparatus

Номер: US20130131611A1
Принадлежит: Abbott Medical Optics Inc

An apparatus and method for dispersing fluid from a fluid dispersal line is provided. The method comprises initiating operation of the medical apparatus, determining whether fluid has been dispersed from the medical apparatus via the fluid dispersal line since said initiating occurred, and assessing whether fluid is available in the fluid dispersal line. If fluid has not been dispersed from the medical apparatus since said initiating occurred and fluid is not available in the fluid dispersal line, the method includes distributing a commanded quantity of fluid plus an amount of fluid determined to fill the fluid dispersal line. Otherwise the method disperses only the commanded quantity of fluid.

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30-05-2013 дата публикации

Occlusion detection for a fluid infusion device

Номер: US20130133438A1
Принадлежит: Medtronic Minimed Inc

A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, a force sensor, and an electronics module. The drive motor assembly regulates delivery of fluid by actuating a piston of a fluid reservoir, and the force sensor generates output levels in response to force imparted thereto during, for example, fluid delivery operations. The electronics module processes the output levels of the force sensor to assess the operating health of the force sensor, to check for occlusions in the fluid delivery path, and to monitor the seating status of the fluid reservoir.

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30-05-2013 дата публикации

MEDICAL FLUID MACHINE WITH SUPPLY AUTOCONNECTION

Номер: US20130138037A1
Принадлежит:

A medical fluid system including: fluid containers and a tube extending from same, each tube including a cap; a pumping cassette including port spikes; a medical fluid machine including: occluders; a shuttle configured to receive the tubes, wherein each tube is associated with one of the occluders; a driving mechanism translating the shuttle; a cap removal device between the cassette and the shuttle; and a control unit programmed to cause: (i) the occluders to pinch their tubes, (ii) cause the driving mechanism to translate the shuttle towards the fluid pumping cassette, the cap removal device engaging the tube caps, (iii) the driving mechanism to translate the shuttle away from the fluid pumping cassette and cap removal device, pulling the tube caps off of the tubes, and (iv) the driving mechanism to translate the shuttle back towards the fluid pumping cassette for the port spikes to spike the occluded tubes. 1. A medical fluid system with supply autoconnection , the system comprising:at least two fluid containers and a tube extending from each of the two containers, wherein each of the tubes includes a cap;a fluid pumping cassette including at least two port spikes; at least two occluders,', 'a shuttle configured to receive the tubes, wherein each of the tubes is operably associated with one of the at least two occluders,', 'a driving mechanism for translating the shuttle, and', 'a cap removal device positionable between the cassette and the translating shuttle; and, 'a medical fluid machine including'}a control unit programmed to cause (i) the occluders to pinch their associated tubes to prevent fluid flow, (ii) the driving mechanism to translate the shuttle holding the occluded tubes towards the fluid pumping cassette, the cap removal device in turn engaging the tube caps, (iii) the driving mechanism to translate the shuttle holding the occluded tubes away from the fluid pumping cassette and the cap removal device, so that the cap removal device pulls the tube ...

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30-05-2013 дата публикации

Dose Setting Mechanism

Номер: US20130138051A1
Принадлежит: SANOFI-AVENTIS DEUTSCHLAND GMBH

A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features () on a first component part () of the drug delivery device and corresponding second maximum dose stop features () on a second component part () of the drug delivery device, with the first and second maximum dose stop features () being designed to limit a relative movement between the first and second component parts (). To limit the maximum dose which can be chosen, a maximum dose limiting device () is provided interposed on the first component part () between the first and second maximum dose stop features (). 17-. (canceled)8. Drug delivery device comprising a dose setting mechanism , the dose setting mechanism comprisingfirst maximum dose stop features on a first component part of said drug delivery device,corresponding second maximum dose stop features on a second component part of said drug delivery device, with the first and second maximum dose stop features being designed to limit a relative rotational movement between said first and second component parts,a maximum dose limiting device interposed on said first component part between said first and second maximum dose stop features and having mating features on a first end fitting to said first maximum dose stop features and replica stop features on a second end replicating said first maximum dose stop features.9. Drug delivery device of claim 8 , wherein said maximum dose limiting device is a maximum dose limiting sleeve claim 8 , comprisinga tubular body with an essentially cylindrical cross-section having open ends on opposite sides in the tubular axis,with said mating features being provided on the one open end of said body fitting to said first maximum dose stop features of said drug delivery device, andwith said replica stop features being provided on the other open end of said body replicating said first maximum dose stop features of said drug delivery device,said mating features defining a ...

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30-05-2013 дата публикации

Infusion Pump and Method Which Inhibits Unintended Tubing Withdrawal

Номер: US20130138074A1
Принадлежит: WalkMed Infusion LLC

A delivery tube is inhibited from unintended withdrawal from an infusion pump which has an internal occlusion clamp that clamps the delivery tube to prevent the free flow of fluid through the tube, by overlapping a blocking lip from a compression edge of the occlusion clamp with a restraint surface of an anvil against which the tubing is compressed and by overlapping a blocking projection from the restraint surface with the compression edge. Inhibition is also achieved by positioning an obstruction protrusion adjacent to the compression edge and the blocking lip to resist the application of exterior physical force to force the occlusion clamp from an occluding position to a non-occluding position. 1. An infusion pump for regulating the flow of medicinal fluid delivered through a delivery tube to a patient , the infusion pump having an internal occlusion clamp which occludes the delivery tube and prevents free flow of the fluid through the delivery tube when in an occluding position and which opens the delivery tube to allow the flow of fluid through the delivery tube when in a non-occluding position;the infusion pump further comprising:a tubing channel in which a first portion of the delivery tube is located within the infusion pump;an anvil located on one side of the tubing channel, the anvil having a restraint surface facing the tubing channel and against which the delivery tube is compressed and occluded when the occlusion clamp is in the occluding position;a compression edge of the occlusion clamp which faces the tubing channel on the opposite side of the tubing channel from the restraint surface, the compression edge moving into adjacency with the restraint surface to compress and occlude the delivery tube between the compression edge and the restraint surface when the occlusion clamp is in the occluding position, the compression edge moving away from the restraint surface to open the delivery tube when the occlusion clamp is in the non-occluding position;a ...

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30-05-2013 дата публикации

VARIABLE FLOW CONTROL DEVICE, SYSTEM AND METHOD

Номер: US20130138075A1
Автор: LAMBERT PAUL
Принадлежит: EMED TECHNOLOGIES CORP. (NV)

A device, system and method are provided for controlling the rate of infusion of fluids during infusion therapy using non-electric infusion devices. Rotation of a flow regulator dial causes an orifice connected to the inlet to modify its position relative to a particular one or more orifices or groove portions, the characteristics of which provide a certain flow rate characteristic. The regulator allows for the infusion pump to infuse at a rate that may be varied during use by the user. 1. A flow rate control device , comprising:an inlet handle including an inlet port;an outlet handle including an outlet port;a seal sealingly engaged between said inlet handle and said outlet handle;at least one of said inlet handle, outlet handle or seal including a plurality of differently sized orifices; andat least a portion of said inlet handle being rotatable relative to said outlet handle to a selectively align one or more of said plurality of differently sized orifices between said inlet port and said outlet port.2. The flow rate control device of claim 1 , wherein said seal includes said plurality of differently sized orifices and rotation of a dial on the inlet handle rotates the seal to change the alignment of said plurality of differently sized orifices relative to the inlet port and outlet port;3. The flow rate control device of claim 1 , wherein said outlet handle includes said plurality of differently sized orifices in fluid communication with said outlet port claim 1 , and rotation of said inlet handle changes the alignment of said inlet port and an orifice through the seal with said plurality of differently sized orifices.4. The flow rate control device of claim 1 , wherein each one of said plurality of differently sized orifices is differently sized from every other one of said plurality of differently sized orifices.5. The flow rate control device of claim 1 , wherein said plurality of differently sized orifices are arranged in groups representing different ...

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20-06-2013 дата публикации

Fluid Exchange Catheter System

Номер: US20130158470A1
Автор: Christos Panotopoulos
Принадлежит: IRRAS AB

A method of infusing and aspirating fluid from the body is provided. The method includes providing a catheter system which includes an inner lumen, the proximal end of which is connected to an infusion mechanism configured to control infusion of a fluid, and an outer lumen, the proximal end of which is connected to an aspiration mechanism configured to control aspiration of fluid from the body. The method also includes activating the infusion mechanism to infuse fluid into the body for a first infusion time period and at a first infusion pressure, disabling the infusion mechanism to stop infusion, and activating the aspiration mechanism to aspirate fluid for a first aspiration time period and at a first aspiration pressure.

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27-06-2013 дата публикации

Coupling an Ultrasound Probe to the Skin

Номер: US20130165005A1
Принадлежит: NEORAD AS

A tape for securing an ultrasound probe to the skin may include a sonolucent silicone gel for transmitting ultrasound from an ultrasound transducer to the body. A method of manufacturing an adhesive silicone product may include a step of treating the adhesive composition or components of the composition to remove air or prevent the formation of air bubbles, in order to provide a sonolucent adhesive product.

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27-06-2013 дата публикации

Self-injection device having needle cover with activation preventer

Номер: US20130165866A1
Автор: Corey Christensen
Принадлежит: Becton Dickinson and Co

A drug delivery device, including a body ( 104, 116 ) having a reservoir ( 160 ) disposed therein for containing a medicament and an injection needle ( 152 ) for penetrating the skin of a patient, the needle ( 152 ) providing a path for the medicament between the reservoir ( 160 ) and the patient. The device also includes a rotor ( 580 ) rotatably disposed in the body ( 104, 116 ) for activating the device upon rotation of the rotor ( 580 ), a needle cover ( 112 ) for covering the injection needle, and a needle cover clip ( 560 ) disposed on the needle cover ( 112 ) to rotate from a first position preventing rotor rotation to a second position permitting rotor rotation.

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27-06-2013 дата публикации

DOSING UNIT, AMBULATORY INFUSION DEVICE COMPRISING DOSING UNIT AND METHOD FOR OPERATING A DOSING UNIT

Номер: US20130165899A1
Принадлежит: ROCHE DIAGNOSTICS INTERNATIONAL AG

A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained. 1. A method for operating a metering unit for an ambulatory infusion device , comprising:a) providing a dosing unit and a driving unit;b) coupling a plunger of the dosing unit, the plunger being located, at least in part, in a metering cavity of a movable member of the metering unit and being adapted for displacement in the metering cavity along a displacement axis;c) coupling the movable member of the dosing unit to the driving unit with the plunger being further coupled to the driving unit;d) moving the movable member into a charging valve position with a position of the plunger relative to the movable member along the displacement axis being maintained;e) decoupling the movable member from the driving unit with the plunger being further coupled to the driving unit;f) displacing the plunger along the displacement axis in a distal direction with a position of the movable member being maintained, thus charging the metering cavity;g) coupling the movable member of the dosing unit with the driving unit, with the plunger being further coupled to the driving unit;h) moving the movable member into a discharging valve position, ...

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04-07-2013 дата публикации

Systems And Methods For Using Photoplethysmography In The Administration Of Narcotic Reversal Agents

Номер: US20130172759A1
Принадлежит:

Provided according to embodiments of the present invention are methods of monitoring and treating respiratory depression that include securing a photoplethysmography (PPG) sensor to a central source site of an individual; administering a central nervous system (CNS) depressant to the individual; processing PPG signals front the PPG sensor with a computer in communication with the PPG sensor; and administering a narcotic reversal agent to the individual if the PPG signals or a physiological parameter derived therefrom are outside a preset value range. Related systems are also described. 1. A method of monitoring and treating respiratory depression comprising:securing a photoplethysmography (PPG) sensor to a central source site of an individual;administering a central nervous system (CNS) depressant to the individual;processing PPG signals from the PPG sensor with a controller in communication with the PPG sensor; andadministering a narcotic reversal agent to the individual if the PPG signals or a physiological parameter derived therefrom are outside a preset value range.2. The method of claim 1 , wherein the narcotic reversal agent is administered to the individual if a respiration rate of the individual is outside the preset value range.3. The method of claim 1 , wherein the narcotic reversal agent is administered to the individual if a respiratory effort of the individual is outside the preset value range.4. The method of claim 1 , wherein the narcotic reversal agent is naloxone.5. The method of claim 1 , further comprising securing to the individual an additional sensor configured to determine at least one parameter selected from respiration rate claim 1 , end-tidal carbon dioxide content claim 1 , blood pressure claim 1 , heart rate and heart rate variability.6. The method of claim 5 , wherein the narcotic reversal agent is administered if (a) the PPG signals or a physiological parameter derived therefrom are outside a first preset value range; and (b) a ...

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11-07-2013 дата публикации

ACCURATE FLOW CONTROL IN DRUG PUMP DEVICES

Номер: US20130178792A1
Автор: Li Po-Ying
Принадлежит: MINIPUMPS, LLC.

The accuracy of drug delivery with drug pump devices may be improved by a combination of pump operation at high flow resistances and pump pressures, pressure-relief mechanisms, and sensor-based feedback for pump control. 1. A high-pressure drug pump device comprising:a drug reservoir;an exit member for fluidically connecting the reservoir with a drug injection site;{'sup': 6', '−1, 'a flow restrictor for restricting fluid flow through the exit member, the flow restrictor having a flow resistance factor of at least 10μl;'}an electrolysis pump comprising a pump chamber in mechanical communication with the drug reservoir via an intervening displacement member, the electrolysis pump being operable to exert a pressure of at least 5 psi to drive the displacement member toward the exit member and thereby force therethrough fluid in the drug reservoir; andcircuitry for operating the pump to generate a pressure of at least 5 psi, the circuitry and the flow restrictor cooperating to cause continuous fluid flow through the exit member at a constant flow rate in the range from about 400 nl/min to about 5 μl/min.2. The device of claim 1 , wherein the pump is operable to exert a pressure of at least 10 psi.3. The device of claim 1 , wherein the pump is operable to exert a pressure of at least 50 psi.4. The device of claim 1 , wherein the pump is operable to exert a pressure of at least 100 psi.5. The device of claim 1 , wherein the pump is operable to exert a pressure of at least 200 psi.6. The device of claim 1 , wherein the smallest inner diameter of the flow restrictor does not exceed 100 μm.7. The device of claim 1 , wherein the smallest inner diameter of the flow restrictor does not exceed 50 μm.8. The device of claim 1 , wherein the flow restrictor has a length in the range from about 1 cm to about 15 cm.9. The device of claim 1 , wherein the exit member comprises the flow restrictor.10. The device of claim 1 , wherein the exit member comprises a cannula connected to the ...

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11-07-2013 дата публикации

IV FLOW RATE REGULATOR AND METHOD OF ITS FABRICATION

Номер: US20130178805A1
Автор: Baid Rishi
Принадлежит: Poly Medicure Limited

An IV flow rate regulator for precision dosage of medical liquids including a first part, a second part with an integrated outlet tubular connector and a mating attachment part with an integrated inlet tubular connector, coupled to one another in a rotatable manner with a first elastic gasket in a depression in the base wall of the second part, a second elastic gasket in a depression in the base wall of the mating attachment part, a dosing passage groove provided between the first and second gaskets, the dosing groove opening progressively the communication between the inlet tubular connector and the outlet tubular connector by rotation of the first and second parts. Also provided is a method for the fabrication of the said IV flow regulator. 1. An IV flow rate regulator for precision dosage of medical liquids comprising:a first part, a second part with at least one integrated outlet tubular connector and a mating attachment part with at least one integrated inlet tubular connector, said first, second and mating attachment parts made of moulded plastic material and being coupled to one another in a rotatable manner about an axis of rotation with a first gasket made of elastomeric material being inter-positioned in a depression integrally made in the base wall of said second part, a second gasket made of elastomeric material being inter-positioned in a depression integrally made in the base wall of said mating attachment part, at least one dosing passage groove being provided between said first and second gaskets, said dosing groove opening progressively the communication between said inlet tubular connector and said outlet tubular connector by means of the relative rotation of said first and second parts.2. The IV flow rate regulator according to claim 1 , wherein said first part comprises a substantially circular wall formed integrally with a side skirt extending upwardly from said circular wall and a side wall extending downwardly from said circular wall in an ...

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18-07-2013 дата публикации

Microfluidic device, microfluidic dosing system and method for microfluidic flow measurement and dosing

Номер: US20130183209A1

A microfluidic device for detecting a flow parameter, includes a channel configured within a base body, the channel including a first inlet for feeding a first fluid and a second inlet for feeding a second fluid so as to form a fluid stream having the first and second fluids within the channel, and further including an output for providing the fluid stream on the output side, a first feeder including a micropump associated with the first inlet for selectively feeding the first fluid to the channel, a second feeder associated with the second inlet for feeding the second fluid to the channel; and a detector for detecting, on the basis of a different physical property of the first fluid and the second fluid within the channel, a measurement value dependent on a current flow parameter of the first or second fluid.

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18-07-2013 дата публикации

Infusion Monitoring Device and Method for Monitoring the Infusion Dripping Rate and Alarming for the Irregularities of the Infusion

Номер: US20130184675A1
Автор: Li Yimin
Принадлежит:

The present invention discloses an intravenous infusion monitoring device for monitoring the infusion dripping rate. This device is attached to an infusion tube above the dripping chamber, including two polar plates forming a capacitor, a capacitance measurement unit electrically connected to the capacitor, a micro control unit (MCU) configured to collect data from the capacitance measure unit and analysis and display the infusion dripping rate. A method for monitoring infusion rate includes setting the infusion solution surface to a specific height in the dripping chamber so that the infusion solution in the tube is conducted and have a pulse change of the capacitance at the moment when a droplet drips down, determining the cycle of the pulse corresponding to the infusion rate and displaying the dripping rate by LCD screen, and alarming when the infusion irregularities occurs such as too fast, too slow or fully stop. 1. An infusion rate monitoring circuit. The said monitoring circuit comprising:a capacitor, the two polar plates of which are placed on both sides of the infusion tube above the dripping chamber;a capacitance measurement unit electrically connected to the said capacitor and is configured to measure the capacitance value of the capacitor;a micro control unit (MCU) electrically connected to the capacitance measurement unit;a LCD; anda LED/buzzer electrically connected to the MCU.2. The infusion monitoring circuit described in claim 1 , wherein the said capacitor of the monitoring circuit is a metal polar plate capacitor made by two metal plates which are placed on the both side of the infusion tube above the dripping chamber claim 1 , or two metal plates are set as one plate placed around the infusion tube above the dripping chamber and another one placed around the infusion dripping chamber. The described capacitor and the monitoring device are clamped outside of the infusion tube above the dripping chamber as a single piece.3. The monitoring circuit ...

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18-07-2013 дата публикации

System, Method, and Apparatus for Estimating Liquid Delivery

Номер: US20130184676A1
Принадлежит: DEKA Products Limited Partnership

A pump for administering an agent to a patient includes a housing, a motor, a gearbox, a sensor, and a controller. The motor may be coupled to housing. The gearbox is operatively connected to said motor. The sensor senses a rotation of said motor. The controller acts to control operation of said motor and monitor the quantity of said agent delivered to said patient. The pump also includes a pump assembly such that the pump is configured such that the pump assembly may be interchangeable from a syringe pump assembly and a peristaltic pump assembly. 12-. (canceled)3. A syringe pump for administering an agent to a patient , the syringe pump comprising:a housing;a lead screw; anda sliding block assembly, said sliding block assembly comprising a cam, a cam projection fixedly coupled to the cam, and a threaded portion capable of engaging and disengaging from said lead screw, said threaded portion configured to be actuated between engagement and disengagement on the lead screw via rotation of the cam and cam projection, wherein said sliding block assembly is positioned within said housing.4. The syringe pump of claim 3 , wherein the sliding block assembly comprises a slot with a straight expanse and an arcuate expanse.5. The syringe pump of claim 4 , wherein the cam is configured such that rotation of the cam causes the cam projection to move within the slot and wherein as the cam projection moves within the straight expanse of the slot claim 4 , the threaded portion is configured to be actuated between engagement and disengagement with the lead screw.6. The syringe pump of claim 5 , wherein the syringe pump further comprises a clamping means configured for clamping any of a range of plunger flange sizes.7. The syringe pump of claim 6 , wherein the cam projection is configured such that it does not enter the straight expanse of the slot until the largest of the range of plunger flange sizes has been released by the means configured for clamping any of a range of plunger ...

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01-08-2013 дата публикации

Devices and methods for selectively lysing cells

Номер: US20130197427A1
Принадлежит: Cabochon Aesthetics Inc

A device for generating microbubbles in a gas and liquid mixture and injection device, the device comprising: a housing defining a mixing chamber; means for mixing solution contained in the mixing chamber to generate microbubbles in the solution; a needle array removably attached to the housing and in fluid connection with the mixing chamber, the needle array including at least one needle; and at least one pressure sensor for measuring tissue apposition pressure, the pressure sensor being mounted on one of the housing and the needle array.

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01-08-2013 дата публикации

Implantable Infusion Devices Including Apparatus For Confirming Fluid Flow And Systems, Apparatus And Methods Associated With Same

Номер: US20130197487A1

Implantable infusion apparatus, systems and methods that involve the use of a sensor that is associated with the catheter outlet. 121-. (canceled)22. A method of monitoring an infusion device that is implanted within a body and includes a reservoir for an infusible substance , a fluid transfer device , a catheter , and a plurality of spaced sensor devices associated with the catheter that sense a characteristic that is representative of fluid flow , the method comprising the step of:wirelessly querying at least two of the spaced sensor devices associated with the catheter.23. A method as claimed in claim 22 , wherein the step of wirelessly querying the sensor devices comprises wirelessly querying the sensor devices associated with the catheter with a device that is external to the body.24. A method as claimed in claim 22 , further comprising the step of:powering the sensor devices with the wireless query.25. A method as claimed in claim 22 , further comprising the step of:determining whether fluid is flowing though the catheter based on the result of the wireless query.26. A method as claimed in claim 22 , further comprising the step of:identifying the location of a blockage or leak based on the result of the wireless query.27. An implantable infusion device claim 22 , comprising:a housing;a fluid transfer device carried within the housing;a power supply carried within the housing and operably connected to the fluid transfer device;a catheter, including a outlet, operably connected to the fluid transfer device; anda plurality of spaced sensor devices, which are not powered by the power supply within the housing, associated with the catheter and configured to measure a characteristic that is indicative of fluid flow through the catheter.28. An implantable infusion device as claimed in claim 27 , wherein the fluid transfer device comprises an electromagnet pump.29. An implantable infusion device as claimed in claim 27 , wherein at least one of the sensor devices ...

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08-08-2013 дата публикации

System, Method, and Apparatus for Estimating Liquid Delivery

Номер: US20130204188A1
Принадлежит: DEKA Products Limited Partnership

A pump, related system, and related method are provided. The pump includes a reservoir, a port, and a plunger. The reservoir delivers a liquid by discharging the liquid through the port coupled to the reservoir. The plunger has a piston coupled to a shaft and is disposed within the reservoir in sliding engagement with an inner surface of the reservoir. The piston defines a liquid side of the reservoir and a non-liquid side of the reservoir whereby movement of the plunger towards the liquid side of the reservoir discharges liquid through the port. The pump also includes a reference-volume assembly and/or a linear position sensor. The reference-volume assembly is coupled to the reservoir at an opposite end of the reservoir relative to the port and includes a reference-volume chamber in acoustic communication with the non-liquid side of the reservoir, a speaker disposed within the reference-volume chamber, and a reference microphone disposed within the reference-volume chamber. The reference-volume assembly and/or linear position sensor may be used to estimate the amount of liquid discharged from the reservoir. 1. A pump , comprising:a reservoir configured to deliver a liquid;a port coupled to the reservoir and configured to discharge the liquid;a plunger having a piston coupled to a shaft, wherein the piston is disposed within the reservoir in sliding engagement with an inner surface of the reservoir, wherein the piston defines a liquid side of the reservoir and a non-liquid side of the reservoir whereby movement of the plunger towards the liquid side of the reservoir discharges liquid through the port; and a reference-volume chamber in acoustic communication with the non-liquid side of the reservoir;', 'a speaker disposed within the reference-volume chamber; and', 'a reference microphone disposed within the reference-volume chamber., 'a reference-volume assembly coupled to the reservoir, wherein the reference-volume assembly comprises2. The pump according to claim 1 ...

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08-08-2013 дата публикации

Wireless strain gauge/flow sensor

Номер: US20130204202A1
Принадлежит: STMicroelectronics lnc USA

A flow rate sensor is provided in a wireless, leadless package. The flow rate sensor includes a MEMs sensor coupled to an ASIC and an antenna. The flow rate sensor is powered by radiation received from a control module adjacent the flow rate sensor. The flow rate sensor is placed within a fluid and monitors the flow rate of the fluid. The control module is not in the fluid and receives flow rate data from the flow rate sensor.

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15-08-2013 дата публикации

Liquid Infusion Apparatus

Номер: US20130211323A1
Автор: LEE Young Gyu
Принадлежит: Woo Young Medical Co., Ltd.

The present invention relates to a liquid infusion apparatus, including: a finger module provided in a main body such that the finger module can elastically move backward from a liquid delivery tube; a tube clamp, in which two clamp bodies spaced apart from each other approach each other by means of restoring force of an elastic member upon the opening of a door during infusion, so as to compress and block the liquid delivery tube; and a tube blockage detection device which detects whether the liquid delivery tube is blocked by a cause, for example, when the outlet-side portion of the liquid delivery tube, which delivers medicinal liquid pumped by a liquid pump during infusion, is bent. 1. A liquid infusion apparatus , comprising:a main body having an opening;a door installed on the main body so as to be openable, wherein when the door is closed, the door faces the opening with a liquid infusion tube interposed between the door and the opening and supports the liquid infusion tube;a finger module comprising a plurality of fingers installed in the main body so as to be movable forward and backward relative to the opening, the fingers moving in conjunction with a cam shaft in a wiggling manner in which the fingers successively move forward to the opening and compress a portion of the liquid infusion tube through the opening;an elastic member applying elastic force to the finger module and biasing the finger module forward so that the liquid infusion tube is elastically compressed by the fingers; andcam shaft drive means rotating the cam shaft so that the fingers move in conjunction with the cam shaft in the wiggling manner.2. The liquid infusion apparatus according to claim 1 , wherein the finger module comprises a mounting block provided such that the fingers are able to move in conjunction with the cam shaft in the wiggling manner and compress the liquid infusion tube claim 1 ,wherein the mounting block is mounted to the main body in such a way that the mounting ...

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15-08-2013 дата публикации

Microfabricated nanopore device for sustained release of therapeutic agent

Номер: US20130211368A1
Принадлежит: Delpor Inc

A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.

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15-08-2013 дата публикации

PUMP AND MONITOR FOR IV PRESSURE INFUSERS

Номер: US20130211378A1
Автор: Miller Paul Joseph
Принадлежит:

A pumping device that can be used with currently-available pressure bag infusers is disclosed. The pumping device is hand-held and lightweight. The device is controlled by a microprocessor. Thus constant pressure to the bag is maintained through automatic adjustment of pumping and venting functions. In addition, a novel, new pressure bag infuser and a modified Luer Lock fitting for use with the pumping device are described. 1. A pumping device , comprising:a housing;a coupler attached to the housing, the coupler configured to attach with an airtight connection to a pressure vessel;an electric air pump in the housing, the pump in pneumatic communication with the pressure vessel;a first pressure sensor in pneumatic communication with the pressure vessel;an electronic valve in pneumatic communication with the pressure vessel;a signaling element;a microprocessor in electronic communication with the pump, the first pressure sensor, the valve, and the signaling element;a power source supplying power to the device; anda switch in communication with the power source and optionally, with the microprocessor.2. The pumping device of further comprising a second pressure sensor in pneumatic communication with the outside environment claim 1 , the second pressure sensor in electronic communication with the microprocessor.3. The pumping device of wherein the housing has a size that is no more than about 20 cm in length and no more than about 6 cm in width.4. The pumping device of wherein the housing comprises metal or plastic.5. The pumping device of wherein the housing is sealed except at the coupler and at intake or exhaust ports.6. The pumping device of wherein the pressure vessel is an airtight bag.7. The pumping device of wherein the airtight bag is configured to be positioned around an IV bag.8. The pumping device of wherein the airtight bag is an integral part of an IV bag.9. The pumping device of wherein the coupler comprises a modified male Luer Lock fitting that is ...

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22-08-2013 дата публикации

BLOOD ACCESS DEVICE

Номер: US20130218073A1
Принадлежит:

A blood access device including a fluid conduit configured to convey a flow of fluid to a target vessel, a second lever element pivotally and resiliently connected to a first lever element such that it may move from a first position to a second position. A biasing force is exerted on the second lever element for moving it from the first position to the second position, and a blocking member may be activated by the second lever element, such that a flow of fluid is decreased when the second lever element is moved from the first position to the second position. The lever elements are configured to be fixed to the target vessel when the second lever element is in the first position, and the second lever element moves to the second position and activates the blocking member if the fixation is at least partially lost. 1. A blood access device comprising:a fluid conduit configured to convey a flow of fluid to a target vessel,a first lever element,a second lever element pivotally and resiliently connected to the first lever element such that the second lever element is movable in a direction from a first position to a second position in relation to the first lever element, and a biasing force is exerted on the second lever element for moving the lever element from the first position to the second position,a blocking member configured to be activated by the second lever element, such that a flow of fluid conveyed by the fluid conduit is decreased when the second lever element is moved from the first position to the second position, whereinthe first and second lever elements are configured to be fixed at a surface of the target vessel when the second lever element is in the first position, such that the fixation to the surface counteracts the biasing force exerted on the second lever element, thereby allowing the second lever element to move to the second position and activate the blocking member if the fixation is at least partially lost.2. A blood access device according ...

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22-08-2013 дата публикации

PREDICTION, VISUALIZATION, AND CONTROL OF DRUG DELIVERY BY INFUSION PUMPS

Номер: US20130218080A1
Принадлежит:

Systems for predicting a drug delivery profile as described herein include at least one drug pump that produces a drug flow. The drug pump dispenses at least a first drug. The system also includes at least one carrier fluid pump that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system further includes a processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow. The model includes a plurality of parameters related to propagation of the mixed flow through the fluid path. 1. A system for predicting a drug delivery profile , the system comprising:at least one drug pump that produces a drug flow, the at least one drug pump dispensing at least a first drug;at least one carrier fluid pump that produces a carrier fluid flow;a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow;a fluid path for carrying the mixed flow between the flow junction structure and a delivery point; anda processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow, wherein the model includes a plurality of parameters related to propagation of the mixed flow through the fluid path.2. The system of claim 1 , further comprising a control module configured to control the drug flow and the carrier fluid flow such that a particular drug delivery profile is achieved at a future time point.3. The system of claim 2 , wherein the control module is further configured to compute a rate of the drug flow and a rate of the carrier fluid ...

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