ПОРШЕНЬ ДЛЯ ПЕРЕМЕЩЕНИЯ ЖИДКОСТИ В УСТРОЙСТВАХ ДЛЯ ИНЪЕКЦИЙ

FIELD: medicine. SUBSTANCE: piston 11 is designed for displacement of liquid inside cylindrical chamber, preferably in injection bottle of double-chamber type. Piston is made so that at least one of its end-face surfaces 12 is of convex form in released state of piston diameter. Degree of end-face surface convexity in released state provides for flat end-face surface 12 in compressed state at smaller diameter of piston. EFFECT: enhanced accuracy of measurement. 13 cl, 6 dwg ЗУСТУГС ПЫ Го (19) РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ ВИ "” 2 141 348. (51) МПК 13) Сл А 61 М 5/315 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 95121647/14, 14.02.1994 (24) Дата начала действия патента: 14.02.1994 (30) Приоритет: 17.02.1993 ЗЕ 9300525-4 (46) Дата публикации: 20.11.1999 (56) Ссылки: ЕР 0111724 А2, 27.09.84. 4$ 4629454 А, 16.12.86. ЕР 0440846 АЛ, 07.02.90. $4 459233, 03.04.75. $Ц 848034, 23.07.81. (85) Дата перевода заявки РСТ на национальную фазу: 17.09.95 (86) Заявка РСТ: ЗЕ 94100117 (14.02.94) (87) Публикация РСТ: М/О 94/19035 (01.09.94) (98) Адрес для переписки: 129010, Москва, ул.Б.Спасская, д.25, стр.3, Союзпатент (71) Заявитель: Фармациа энд Апджон АБ ($Е) (72) Изобретатель: Биргер Хьертман (3Е), Олле Льюнгквист ($5Е) (73) Патентообладатель: Фармациа энд Апджон АБ ($Е) (54) ПОРШЕНЬ ДЛЯ ПЕРЕМЕЩЕНИЯ ЖИДКОСТИ В УСТРОЙСТВАХ ДЛЯ ИНЪЕКЦИЙ (57) Реферат: Устройство предназначено для использования в медицине для инъекций. Поршень (11), предназначенный для использования при перемещении жидкости внутри цилиндрической камеры, предпочтительно в баллончике для инъекций двухкамерного типа, выполнен так, что по меньшей мере одна из его торцевых поверхностей (12) имеет выпуклую форму в несжатом состоянии диаметра поршня, а степень выпуклости торцевой поверхности в несжатом состоянии обеспечивает по существу плоскую торцевую поверхность (12) в сжатом состоянии при меньшем диаметре поршня. Технический результат - повышение точности процесса ...

УСТРОЙСТВО РАСПРЕДЕЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ, УСТРОЙСТВО ВПРЫСКИВАТЕЛЯ, СПОСОБ ДЛЯ УМЕНЬШЕНИЯ ИЗБЫТОЧНОЙ ДОЗЫ ИЗМЕРЯЕМОГО ПРОДУКТА

Устройство предназначено для распределения лекарственного средства. Устройство включает патрон, предназначенный для содержания в нем инъецируемого продукта, и впрыскиватель, прикрепленный к патрону. Впрыскиватель включает механизм привода, содержащий дозировочную втулку, имеющую дозировочную головку на ее ближайшем к месту прикрепления конце и шток с резьбой, подсоединенный к втулке и способный перемещаться в осевом направлении в патрон при вращении головки по часовой стрелке для установки лимба на требуемую дозировку, подлежащую инъецированию. Храповой механизм расположен в корпусе впрыскивателя и включает способную вращаться деталь, прикрепленную к дозировочной втулке для вращения с ней, и блокировочное гнездо в зацеплении со способной вращаться деталью. Храповой механизм позволяет осуществлять вращательное движение втулки только в направлении по часовой стрелке. Механизм расцепления прикреплен к корпусу узла жидкокристаллического дисплея и включает штифт, который проходит в способную ...

УСТРОЙСТВО РАСПРЕДЕЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ, УСТРОЙСТВО ВПРЫСКИВАТЕЛЯ, СПОСОБ ДЛЯ УМЕНЬШЕНИЯ ИЗБЫТОЧНОЙ ДОЗЫ ИЗМЕРЯЕМОГО ПРОДУКТА

Устройство распределения лекарственного средства, включающее патрон, предназначенный для содержания в нем инъецируемого продукта, и впрыскиватель, прикрепленный к патрону. Впрыскиватель включает механизм привода, содержащий дозировочную втулку, имеющую дозировочную головку на ее ближайшем к месту прикрепления конце и шток с резьбой, подсоединенный к втулке и способный перемещаться в осевом направлении в патрон при вращении головки по часовой стрелке для установки лимба на требуемую дозировку, подлежащую инъецированию. Храповой механизм расположен в корпусе впрыскивателя и включает способную вращаться деталь, прикрепленную к дозировочной втулке для вращения с ней, и блокировочное гнездо в зацеплении со способной вращаться деталью. Храповой механизм позволяет осуществлять вращательное движение втулки только в направлении по часовой стрелке. Механизм расцепления прикреплен к корпусу узла жидкокристаллического дисплея и включает штифт, который проходит в способную вращаться деталь храпового ...

МЕХАНИЗМ ИНДИКАЦИИ ДЛЯ АВТОМАТИЧЕСКОГО АППЛИКАТОРА, В ЧАСТНОСТИ, ДЛЯ ИНСУЛИНА

... 1. Механизм индикации для автоматического аппликатора, в частности, для инсулина или других жидких медикаментов, в частности, для многократного инъекционного введения установленных доз лекарственного препарата из сменного контейнера, содержащий корпус аппликатора, блок из по меньшей мере двух гильз, подвижно соединенных друг с другом, причем индикаторная гильза (2), установленная на приводной гильзе (1) непосредственно в корпусе (4) аппликатора содержит только индикаторную маркировку (2.1) на своей наружной поверхности, отличающийся тем, что индикаторная гильза (2), содержащая только индикаторную маркировку (2.1) на своей гладкой наружной поверхности, установлена только с возможностью скольжения, соосно и продольно посредством шпоночного соединения непосредственно на наружной поверхности отдельной приводной гильзы (1), без соприкосновения с внутренней поверхностью корпуса (4) аппликатора и соединена своим дистальным концом соосно и непосредственно с отдельной тянуще-толкающей контрольной ...

ПРИВОДНОЙ УЗЕЛ, ШТОК ПЛУНЖЕРА, УСТРОЙСТВО ДЛЯ ДОСТАВКИ ЛЕКАРСТВЕННОГО ПРЕПАРАТА И ПРИМЕНЕНИЕ ПРУЖИНЫ

... 1. Выполненный с возможностью возврата в исходное положение приводной узел для устройства для доставки лекарственного препарата, содержащий- корпус (10А, 10В, 10С), имеющий проксимальный конец (100Р) и дистальный конец (100D);- шток (20) плунжера, выполненный с возможностью поворота относительно корпуса (10А, 10В, 10С) и выполненный с возможностью смещения в аксиальном направлении относительно корпуса (10А, 10В, 10С) между проксимальным исходным положением и дистальным конечным положением;- приводной элемент (30), предназначенный для смещения штока (20) плунжера в дистальном направлении к конечному положению при выдаче дозы; и- стопор (50);при этом приводной узел выполнен с такой конфигурацией, что- приводной элемент (30) выполнен с возможностью приведения его в действие для ввода его во взаимодействие со штоком (20) плунжера для образования разблокируемого первого блокировочного средства, при этом первое блокировочное средство может быть приведено в действие для блокировки перемещения ...

ПРИВОДНОЙ УЗЕЛ, ШТОК ПЛУНЖЕРА, УСТРОЙСТВО ДЛЯ ДОСТАВКИ ЛЕКАРСТВЕННОГО ПРЕПАРАТА И ПРИМЕНЕНИЕ ПРУЖИНЫ

... 1. Приводной узел для устройства для доставки лекарственного препарата, содержащийкорпус (10А, 10В, 10С), имеющий проксимальный конец (100Р) и дистальный конец (100D);шток (20) плунжера, выполненный с возможностью смещения в аксиальном направлении и с возможностью поворота относительно корпуса (10А, 10В, 10С) между первым угловым положением и вторым угловым положением;приводной элемент (30), выполненный с возможностью смещения в аксиальном направлении; иповоротный смещающий элемент (50), выполненный с возможностью приведения в действие для передачи упругого смещающего усилия штоку (20) плунжера;при этом приводной узел выполнен с такой конфигурацией, что для задания дозы:приводной элемент (30) может быть смещен в проксимальном аксиальном направлении относительно корпуса (10А, 10В, 10С) и штока (20) плунжера из исходного положения в положение задания дозы;при задании дозы шток (20) плунжера поворачивается в первом направлении поворота и после поворота в первом направлении поворота поворачивается ...

KARTUSCHENLOSE MULTIDOSIS-INJEKTIONSVORRICHTUNG

Vorrichtung und Verfahren zum Dosieren einer Substanz

Die vorliegende Erfindung bezieht sich auf eine Vorrichtung zum Dosieren einer Substanz mit mindestens einem drehbaren Element (1) und mindestens einem dem Element (1) zugeordneten Kodierungselement (b, c, d), mit welchem die Drehposition des drehbaren Elements (1) erkannt werden kann, gekennzeichnet durch mindestens ein Referenzelement (6), welches ein Referenzsignal nur bei vorgegebenen Positionen oder Positionsänderungen erzeugt sowie auf ein Verfahren zum Bestimmen der Drehposition eines zum Einstellen einer Dosis dienenden drehbaren Elements (1), wobei die Drehposition durch eine Kodierung festgestellt wird, welche nur ausgelesen oder ausgewertet wird, wenn ein Referenzsignal bei vorgegebenen Drehpositionen oder Positionsübergängen erzeugt wird.

Dispensing mechanism for a medical device

Dispensing mechanism for a medical device

A dispensing mechanism 1, such as for administering a dosage of a medicament from a liquid injector or a powder inhaler, includes a push button or rotary dial dosage setter 7 for setting the dosage of a medicament to be administered and moveable in a first direction for setting the dose and in a second direction for administering the dose. An indicator 34 is arranged to be displaced by a predetermined movement of the dosage setter 7 and is configured to remain unmoved relative to said body of the mechanism during at least part of said movement of the dosage setting means. Two spaced indents 35a,35b on the indicator and a protrusion 36 on a window 31 combine with body protrusions 33a,33b the spacing of which provide lost motion between the push button 7 and indicator 34.

METERING UNIT FOR ADJUSTING FINE DOSAGES

LIQUID DELIVERY DEVICE AND PROCEDURE FOR DECREASING THE TRÖPFELNS

INJECTION DEVICE WITH TORSION BAR AND SWIVELLING ONE ANNOUNCEMENT

DRUG INJECTION DEVICE WITH RESETTING OF FACILITATING DRIVE ARRANGEMENT

DOSE RIGGING DEVICE

RE-USABLE DELIVERY DEVICE FOR MEDICINES

INJECTION DEVICE

AN EXHIBITING SYRINGE A TILTABLE MOTHER

Microdosing

A dosing system for transferring an aseptic fluid in dosages into a container, comprising a peristaltic pump configured such that the filling accuracy for fill volumes of the aseptic fluid < 100μL is ± 3μL.

Accurate metering system

Longitudinal compensation for an adjusting device of an injection device

An indication mechanism for an automatic applicator, particularly for insulin

The present invention concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, comprising an assembly of at least two barrels movably coupled to each other is characterised in that a dose indication barrel (2) is mounted on a driving barrel (1) ands contains only a dose scale (2.1) on its external surface and is further co-axially connected to a pull-push control nut (3).

Medication injector apparatus with drive assembly that facilitates reset

Recyclable medication dispensing device

ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE

An assembly for a drug delivery device (1) comprises a housing (5), a rotation member (15), a drive member (16) and at least one correction member (7). The rotation member (15) is adapted to be rotated with respect to the housing (5) in a first rotational direction for delivering a dose of a drug (11). The drive member (16) is coupleable to the rotation member (15) for delivering the dose. In a delivery mode, the drive member (16) and the rotation member (15) are coupled such that the drive member (16) follows rotational movement of the rotation member (15) in the first rotational direction due to mechanical interaction of the rotation member (15) and the drive member (16). In a correction mode, the rotation member (15) and the drive member (16) are decoupled such that the rotation member (15) is rotatable in the first rotational direction with respect to the drive member (16). For switching from the delivery mode into the correction mode, the correction member (7) is moveable with respect ...

DRUG DELIVERY DEVICE AND METHOD OF MANUFACTURING A DRUG DELIVERY DEVICE

The present application relates to drug delivery device (5) and a and method of manufacturing a drug delivery device with a housing (10) having a proximal end and a distal end, a cartridge (15) adapted to accommodate a drug, a cartridge retaining member (45) adapted to retain the cartridge, the cartridge retaining member being secured to the housing, and a spring washer (50) being arranged within the housing so as to exerting a force on the cartridge and securing the cartridge against movement with respect to the cartridge retaining member and against movement with respect to the housing.

DISPENSING MECHANISM FOR A MEDICAL DEVICE

A dispensing mechanism for administering a dosage of a medicament includes dosage setting means (7) for setting the dosage of a medicament to be administered; expelling means (15) for expelling a medicament from a medicament container; and coupling means (21) operatively coupled with the dosage setting means (7) and the expelling means (15), wherein the coupling means (21) is arranged to convert displacement of the dosage setting means (7) into a displacement of the expelling means (15) in a first direction, wherein the expelling means (15) includes a ratchet means (18a, 18b), and wherein the mechanism includes a first and a second independently moveable resisting pawl (14a, 14b) means facing a common side of the ratchet means (18), the first and the second resisting pawl means (14a, 14b) being configured to engage with the ratchet means (18a, 18b) and resist displacement of the expelling means (15) in a second direction opposite to said first direction.

DISPENSING MECHANISM FOR A MEDICAL DEVICE

A dispensing mechanism for administering a dosage of a medicament includes dosage setting means (7) for setting the dosage of a medicament to be administered; expelling means (15) for expelling a medicament from a medicament container; and coupling means (21) operatively coupled with the dosage setting means (7) and the expelling means (15), wherein the coupling means (21) is arranged to convert displacement of the dosage setting means (7) into a displacement of the expelling means (15) in a first direction, wherein the expelling means (15) includes a ratchet means (18a, 18b), and wherein the mechanism includes a first and a second independently moveable resisting pawl (14a, 14b) means facing a common side of the ratchet means (18), the first and the second resisting pawl means (14a, 14b) being configured to engage with the ratchet means (18a, 18b) and resist displacement of the expelling means (15) in a second direction opposite to said first direction.

SYRINGE WITH ELECTRONIC REPRESENTATION OF PARAMETERS

A syringe having a dose setting mechanism, a button which can be operated to inject a set dose, a switch operated at a time between the start and the completion of the injection and an electronic representation of parameters such as magnitudes of the set dose and the late st injected dose, which syringe further has a stop watch which is reset and started when the switch is operated. The status of the watch function is electronically represented and is together with the electronic represented parameters reproduced in a display showing the number of hours passed since the operation of the switch by switching on a corresponding number of 30.degree. segments of a circle. Dose sizes are show n by common Arabic numerals.

IMPROVED MEDICATION DELIVERY PEN

A medication delivery pen includes a housing having an actuator disposed in the proximal end of the housing for setting and administering a dosage of medication, a medication-containing cartridge assembly having a cartridge with a pierceabl y sealed distal end, an open proximal end removably attachable to the distal end of t he housing, and a piston in sliding, fluid tight engagement within the cartridge. A driv e mechanism is coupled between the actuator and the cartridge to exert an axial force on th e piston to inject the set dosage of medication. The actuator triggers the drive mechani sm to administer the injection of medication held in the cartridge and a processor is coupled to the actuator to determine a value equal to the dosage set by the actuator. T he drive mechanism includes a pair of half nuts in rotational engagement with the actuator, a non-rotatable lead screw having a distal end for exerting the axial force on the piston to inject the set dosage of medication, a proximal ...

An injection device having a dose setting member for triggering the actuator mounted distally of a product distribution.

Antriebs- und Dosiervorrichtung für eine Injektionsvorrichtung zur Ausschüttung eines flüssigen Produkts, die Antriebs- und Dosiervorrichtung umfassend: a) ein Gehäuse (1), b ein Dosiseinstellglied (2), welches für die Einstellung der auszuschüttenden Produktdosis relativ zu dem Gehäuse (1) drehbar ist. c) ein Betätigungsglied (8), welches aus einer unbetätigten Position, die es während der Einstellung der auszuschüttenden Produktdosis einnimmt, in eine betätigte Position, die es während der Produktausschüttung einnimmt, verschiebbar ist, wobei das Verschieben des Betätigungsglieds (8) in die betätigte Position eine Produktausschüttung auslöst und das Betätigungsglied (8) einen Betätigungsabschnitt (8a) aufweist, auf den ein Benutzer der Antriebs- und Dosiervorrichtung Zugriff hat und mittels dem der Benutzer das Betätigungsglied (8) aus der unbetätigten Position in die betätigte Position verschieben kann, d) wobei der Betätigungsabschnitt (8a) distal des Dosiseinstellglieds (2) angeordnet ...

Anzeigeeinrichtung für ein Injektionsgerät.

Described is a display for a medical injector (1) in which the injection dose can be pre-selected by turning a control knob (2) and subsenquently injected by moving the knob (2) longitudinally. Resting against the control knob (2) in the injector are switching means (7, 8) which actuate switches (10, 11, 12) whose positions are transmitted to a circuit board (13). By virtue of the organization of the circuit board (13), which conveniently includes a processor, values such as the injection dose selected, the total dose already injected, etc., plus operating-status signals are output to a display unit (15).

Medication dosage calculator

Medication dosage calculator has a dispenser for medication with a scale on the body, with at least two discrete numbered points in a row, structured according to the characteristics of the user's body such as weight, age, size and body surface area. This allows the user to see the dosage required according to the applications.

Injection device for dispensing a medicament

Injection device for dispensing a medicament, comprising: a cartridge module, a dispensing mechanism which is actuated to dispense the injectable preparation, a dose-setting mechanism for setting the dose at which the injectable preparation is dispensed when the dispensing mechanism is actuated, the dose-setting mechanism comprising: a housing part (11) in which at least part of the dispensing mechanism is received, a display sleeve (13) rotatable therein, and an insertion sleeve (15) that can be inserted into the housing part (11), wherein - the insertion sleeve (15) has, on its outer face, a raised surface section (20) that is transparent at least in some areas, and - the housing part (11) has a recess (25) which is open at its distal edge (24) and which receives the insertion sleeve (15) in a rotationally fixed manner from the direction of the open end of the recess (25), and insertion sleeve for an injection device, dose-setting mechanism for an injection device for dispensing a medicament ...

Drug Delivery Device

A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a track comprising a sequence of encoded images; and a sensor directed at the track of the cylindrical member and configured to detect features of the encoded images.

DOSE SETTING DEVICE FOR AN INJECTION DEVICE

A dosing device for an injection device, the dosing device including an actuating element for adjusting and/or dispensing a dose from the injection device, a thrust element for generating a forward movement for discharging a dose and a coupling to which the actuating element and the thrust element are coupled such that a rotational movement of the actuating element is transmitted directly to the thrust element and an axial movement of the actuating element is different than an axial movement of the thrust element. 1. An injection device with an ampoule containing a substance and a dose setting device , said dose setting device comprising:a restrictor element for restricting a maximum total dose of substance which can be set and dispensed from the ampoule; andan operating element for setting a dose which is operatively coupled with the restrictor element so that the restrictor element moves during a dose setting movement of the operating element from an initial position inside the dose setting device toward a stop in order to block the movement of the restrictor element, thereby blocking the movement of the operating element in a dose setting direction and restricting the maximum total dose set;wherein the restrictor element is coupled with the operating element so that the restrictor element moves relative to the dose setting device back to the initial position as the set dose is being dispensed.2. The injection device according to further comprising a drive element which is configured to push on a stopper of the ampoule for dispensing substance from the injection device.3. The injection device according to wherein the drive element is a threaded rod.4. The injection device according to wherein the restrictor element is guided in a thread of the threaded rod.5. The injection device according to wherein the stop is an end of a thread of the threaded rod claim 4 , and/or an axial stop and/or a radial stop on the threaded rod.6. The injection device according to ...

A dosage measuring and administration device based on two parameters

A dose measuring and/or administration device, which utilises a personal physiological biometric scale 2 e.g. age or weight, to measure and make available for administration, consumption or use a substance for the treatment, maintenance or prophylaxis of a person or animal, referenced to a datum point or mark which is varied by a secondary biometric scale 3 e.g. height, temperature, or use of the substance. The syringe type device has a first scale 2 on the plunger 1 and a second scale 3 on a rotating collar 4, which may be clear or have the second gradation provided on its edge. The dose measurement according to the first scale, for example based on the age of the patient, is modified by the second scale, for example based on the weight of the patient.

Leak prevention in injection device

OPTICAL DOSE MEASUREMENT IN SYRINGES

VORRICHTUNG FÜR DIE IN-DACH-VERBINDUNG VON WENIGSTENS ZWEI PLATTENFÖRMIGEN BAUTEILEN AUF EINEM SCHRÄGDACH

INJECTION DEVICE WITH OPTICAL SENSOR

VORRICHTUNG FÜR DIE IN-DACH-VERBINDUNG VON WENIGSTENS ZWEI PLATTENFÖRMIGEN BAUTEILEN AUF EINEM SCHRÄGDACH

INJEKTIONSGERÄT WITH A MAGNETORESISTIVEN SENSOR

DEVICE FOR IN-ROOF-CONNECTION OF AT LEAST TWO PLATTENFÖRMIGEN CONSTRUCTION UNITS ON A DIAGONAL ROOF

SYRINGE WITH ELECTRONIC PARAMETRIC REPRESENTATION

PIN-WELL-BEHAVED SYRINGE ALSO BY A CAP OF OPERATION DOSING CLUTCH

Syringe accuracy enhancing device

MEASURED DOSE SYRINGE

Networked system for interactive communication and remote monitoring of drug delivery

DETERMINATION OF A DOSE SET AND DELIVERED IN A MEDICATION DELIVERY DEVICE

Sensing systems are disclosed for determining the relative rotational movements of members of a medication delivery device which are proportional to the amount of a dose set and delivered by the medication delivery device. The sensing system comprises a first sensor component secured to a first member and a second sensor component secured to a second member. During dose setting, the second member is coupled to a third member which rotates relative to the first member in proportion to the dose set. During dose delivery, the second member is coupled to a fourth member which rotates relative to the first member in proportion to the dose delivered. The sensing system separately detects the relative rotational positions of the first and second sensor components during dose setting and dose delivery, and provides outputs used to determine the amounts of the set and delivered doses. The sensing system outputs this information to a controller which determines the amount of the dose set and delivered ...

MEDICATION INJECTOR APPARATUS WITH DRIVE ASSEMBLY THAT FACILITATES RESET

The invention relates to a medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. The injection pen also may include an injection clicker assembly. The injection pen also may include a doseable quantity identifier. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.

MEDICATION INJECTOR APPARATUS WITH DRIVE ASSEMBLY THAT FACILITATES RESET

The invention relates to a medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. The injection pen also may include an injection clicker assembly. The injection pen also may include a doseable quantity identifier. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.

ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE

An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device ...

ASSEMBLY FOR A DRUG DELIVERY DEVICE

An assembly for a drug delivery device (1), comprises a housing (2), a dose member (22), a guide track (42) and a spring member (26). The dose member (22) is adapted to be rotated in a dose setting direction with respect to the housing (2) for setting a dose of a drug (5) and to be rotated in a dose delivery direction with respect to the housing (2) for delivering the set dose. The dose member (22) comprises a guide feature (46). The guide track (42) is configured to mechanically cooperate with the guide feature (46). The guide track (42) comprises a first section (43A) and a second section (43B) which are connected to each other via a connection region (55). The first section (43A) defines an angular start position (54) for the guide feature (46) and the second section (43B) defines an axial stop position (56) for the guide feature (46). When the dose member (22) is rotated in the dose setting direction, the guide feature (46) is angularly displaced from the angular start position (54) ...

RECYCLABLE MEDICATION DISPENSING DEVICE

A multi-use pen-shaped medication dispensing device (20) made of a plastic material that is recyclable after the contents of the medication cartridge (40) have been exhausted. The device (20) is made of a minimal number of parts, which include a housing (22), a dial assembly (34), a generally cylindrical button assembly (32) located within t he proximal end (50) of the dial assembly (34), an internally threaded nut (36), and an externally threaded leadscrew (38). The device (20 ) is arranged so that the dial (34) must be rotated to the zero dose position prior to setting a dose. The device (20) includes a lockout mechanism (52) that prevents the dial (34) from being depressed during dosing. The device (20) further includes a mechanism (157) that limit s the maximum dosage that can be dialed up and a mechanism (230, 234) that prevents the user from dialing up a dosage greater than that remaining in the cartridge (40).

IMPROVED MEDICATION DELIVERY PEN

A medication delivery pen includes a housing having an actuator disposed in the proximal end of the housing for setting and administering a dosage of medication, a medication-containing cartridge assembly having a cartridge with a pierceabl y sealed distal end, an open proximal end removably attachable to the distal end of t he housing, and a piston in sliding, fluid tight engagement within the cartridge. A driv e mechanism is coupled between the actuator and the cartridge to exert an axial force on th e piston to inject the set dosage of medication. The actuator triggers the drive mechani sm to administer the injection of medication held in the cartridge and a processor is coupled to the actuator to determine a value equal to the dosage set by the actuator. ...

ACTUATION MECHANISM

An injection device with electronic detecting means

本发明涉及具有电子检测工具的注射装，特别是一种用来注射一定剂量药物如治疗糖尿病所用胰岛素的注射装置（1），在剂量配制阶段，能量被蓄积在注射装置（1）的一个弹簧构件（9，24）内。在对先前配制剂量进行注射时，蓄积的能量被释放出来并被用来驱动注射机构。注射装置（1）还包括有配制剂量数电子检测工具以及/或已注射剂量数电子检测工具。电子检测工具可储存并/或记录与注射装置（1）注射有关的数据。

Hypodermic syringe stérilisable and sterilized

ACCURATE METERING SYSTEM

The present invention is directed to metering devices, systems, and methods that mitigate differential thermal expansion/contraction for the efficient, accurate, and reproducible metered delivery of fluids. The present invention allows the net fluid volume and a plunger location within a fluid dispensing container to automatically adjust under the influence of differential thermal expansion/contraction between the fluid and the fluid dispensing container that the fluid is contained within. Further, the present invention allows the metering system drive to sense the adjusted plunger (11) location and allows the metering system drive to re-zero itself to produce an accurate volumetric delivery of fluid from the fluid dispensing container (5) . The metering system includes means for controlling the travel of the metering system drive (14) , and hence the travel of the plunger into the fluid dispensing container, for delivering accurate/precise amounts of the fluid from the fluid dispensing ...

ADMINISTRATION INSTRUMENT FOR MEDICAL USE

An administration instrument includes an injection button which can be pressed at an angle that is not parallel to the needle with respect to a direction in which the needle is inserted into the skin. As a result, it is possible to prevent the force of pressing the injection button from being transmitted in a direction of inserting the needle into the skin deeper than the initial insertion of the needle, thereby achieving an administration under a stable state.

Fluid Discharge Device, Method for Producing and Method for Operating a Fluid Discharge Device for Discharging a Fluid

A fluid discharge device for discharging a fluid has at least one release device for releasing the fluid from a fluid storage container. In addition, the fluid discharge device has a spring, which is tensioned between the release device and a force sensor, and which is designed to exert a restoring force on the force sensor with the releasing of the fluid. Finally, the fluid discharge device has the force sensor, which is designed to detect the restoring force acting on the force sensor with the releasing of the fluid.

Syringe with tiltable nut for quick piston disengagement

In a syringe dosing mechanism a threaded spindle (1) and a nut (3) cooperates so that relative rotation thereof moves the nut (3) along the spindle (1). The nut (3) has two intersecting bores (12, 15). The first bore (15) has an inner thread (7) matching the outer thread (2) of the spindle (1) and the second bore (12) is smooth and fits slidingly over the spindle (1). The nut (3) is tiltable between a first and a second position. In the first position the threaded bore (15) is coaxial with the spindle (1) and in the second position the smooth bore (12) is coaxial with the spindle (1). The nut (3) is at a first side hinged to a piston rod (6)so that exertion of a force by the nut (3) on the piston rod (6) in a direction (10) by which an injection is performed will tilt said nut (3) into its first position. A piston withdrawal member acts at a second side of said nut diametrically opposite said first side so that the nut (3) is tilted to its second position when the withdrawal member applies ...

УСТРОЙСТВО ДЛЯ ДОСТАВКИ ЛЕКАРСТВЕННОГО ПРЕПАРАТА И СПОСОБ ИЗГОТОВЛЕНИЯ УСТРОЙСТВА ДЛЯ ДОСТАВКИ ЛЕКАРСТВЕННОГО ПРЕПАРАТА

FIELD: medicine. SUBSTANCE: group of inventions relates to medical equipments, namely to device for medication delivery and to method of manufacturing device for medication delivery. Device for medication delivery contains case, which has proximal end and distal end, cartridge, adjusted for placement of medication, fixing element of cartridge, adjusted for holding cartridge and spring washer. Fixing element of cartridge is fixed to case. Spring washer is located inside case for application of effort to cartridge and cartridge fixation, preventing displacement of cartridge relative to cartridge fixing element. Spring washer is curved in axial and/or radial direction. Method of manufacturing abovementioned device of medication delivery contains providing case, providing cartridge, providing cartridge fixing element, adjusted for holding cartridge, placement of spring washer inside case, and attachment of cartridge fixing element to case, which results in loading spring washer in order to apply effort to cartridge and cartridge fixation, preventing its displacement relative to cartridge fixing element. EFFECT: invention makes it possible to increase workability with respect to control of dosage and/or increase repeatability of dosage in connection with application of different cartridges. 21 cl, 6 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 534 610 C2 (51) МПК A61M 5/315 (2006.01) A61M 5/24 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2011119019/14, 08.10.2009 (24) Дата начала отсчета срока действия патента: 08.10.2009 (72) Автор(ы): ХАРМС Михаэль (DE), РААБ Штеффен (DE) 13.10.2008 EP 08017889.0 (43) Дата публикации заявки: 20.11.2012 Бюл. № 32 R U (73) Патентообладатель(и): САНОФИ-АВЕНТИС ДОЙЧЛАНД ГМБХ (DE) Приоритет(ы): (30) Конвенционный приоритет: (45) Опубликовано: 27.11.2014 Бюл. № 33 2004256 C1, 15.12.1993. US 2007/0021718 A1, 25.01.2007. WO 96/17640 A1, 13.06.1996. US 2007/0142789 A1, 21.06 ...

Hypodermic syringe for injection of medication from the housing or an ampoule

The hypodermic syringe (1), for the administration of a medication (5) contained in the housing (2) or from an ampoule, has a measurement unit (17) coupled to the plunger (11) which registers the relative position of the plunger (11) in the syringe housing (2). The plunger position is proportional to the level of medication in the syringe. The measurement unit is coupled to a circuit which calculates the vol. of medication within the syringe or the ampoule, or the amount of medication injected, and triggers an acoustic indicator.

Vorrichtung zur Verabreichung eines fluiden Produkts mit optischer Abtastung

Eine Vorrichtung zur Verabreichung eines fluiden Produkts weist eine Messeinrichtung zur berührungslosen Messung einer Stellung zwischen wenigstens zwei relativ zueinander beweglichen Elementen (1; 3) auf. Die Messeinrichtung umfasst wenigstens zwei optische Sensoren (5, 6; 16, 17; 19, 20), die zueinander feststehend an wenigstens einem ersten Element (1) und einem zu dem wenigstens einen ersten Element beweglichen zweiten Element (3) gegenüber angeordnet sind. Ferner ist ein Oberflächenprofil (8) auf dem zweiten Element (3) vorgesehen, das bei der Bewegung des ersten Elements (1) und des zweiten Elements (3) relativ zueinander für jeden der optischen Sensoren einen unterschiedlichen vorbestimmten Profilverlauf vorsieht. Bei einem Verfahren zur berührungslosen Messung einer Stellung zwischen den zueinander beweglichen Elementen (1; 3) nimmt jeder der optischen Sensoren (5, 6; 16, 17; 19, 20) bei einer Bewegung des ersten Elements (1) gegenüber dem zweiten Element (3) entlang dem Oberflächenprofil ...

Injection unit which can be coupled to an ampoule, comprises an adjusting element for regulating the ampoule substance concentration

An injection arrangement (1) which can be coupled to an ampoule, comprises an adjusting element for regulating the concentration of a substance in the ampoule. The adjusting element (2,3) consists of a turn switch (3a,3c), a push switch (3b), a press switch (3d) and/or a dosing button.

Leak prevention in torsion-spring cartridge injector

An injection device has a plunger which retracts from a cartridge bung between doses in order not to promote leakage. The device is preferably a torsion spring injector having a main housing 504, a plunger 8, a drive gear 7 and a release trigger 506. The plunger comprises a leadscrew 9 with a cap 11 which engages the bung (12, figure 2). Rotation of the drive gear around the leadscrew drives the plunger axially towards the bung. The release trigger has a locking ring 520 with axially extending teeth 521 for engaging with corresponding teeth 519 on the drive gear. The teeth may be curved (figures 3B­-3D), or have beveled ends (figure 4A), or the trigger may slide in a doglegged slot 522, such that movement of the release trigger into its rest position causes counter-rotation of the drive gear so as to retract the plunger away from the bung.

Leak prevention injection device

CARTOUCHE LOTS MULTI-DOSE INJECTION DEVICE

DOSAGE SYRINGE

DOSAGE SYRINGE.

RANGE FOR A RIGGING DEVICE OF AN INJECTION DEVICE

SPRAYING DEVICE WITH DRIVING DEVICE, WHICH RESETTING SIMPLIFIES

Syringe comprising a tiltable nut

An indication mechanism for an automatic applicator, particularly for insulin

The present invention concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, comprising an assembly of at least two barrels movably coupled to each other is characterised in that a dose indication barrel (2) is mounted on a driving barrel (1) ands contains only a dose scale (2.1) on its external surface and is further co-axially connected to a pull-push control nut (3).

Assembly for a drug delivery device and drug delivery device

An assembly for a drug delivery device (1) comprises a housing (5), a rotation member (15), a drive member (16) and at least one correction member (7). The rotation member (15) is adapted to be rotated with respect to the housing (5) in a first rotational direction for delivering a dose of a drug (11). The drive member (16) is coupleable to the rotation member (15) for delivering the dose. In a delivery mode, the drive member (16) and the rotation member (15) are coupled such that the drive member (16) follows rotational movement of the rotation member (15) in the first rotational direction due to mechanical interaction of the rotation member (15) and the drive member (16). In a correction mode, the rotation member (15) and the drive member (16) are decoupled such that the rotation member (15) is rotatable in the first rotational direction with respect to the drive member (16). For switching from the delivery mode into the correction mode, the correction member (7) is moveable with respect ...

Smart wearable injection and/or infusion device

A delivery device for delivering a medical fluid to a patient has a housing configured for receiving a container at least partially filled with the medical fluid. The delivery device further has a drive mechanism associated with the housing configured for delivering the medical fluid from the container to the patient in a dosing procedure. The delivery device further has a module configured for detecting at least one of a property of the dosing procedure and a property of the medical fluid. The module has at least one dose detection sensor configured for detecting an initiation, progression, and completion of the dosing procedure based on a position of a stopper within the container. The module further has at least one temperature sensor configured for measuring a temperature of the medical fluid within the container based on a temperature of the container.

DETERMINATION OF A DOSE SET AND DELIVERED IN A MEDICATION DELIVERY DEVICE

Sensing systems are disclosed for determining the relative rotational movements of members of a medication delivery device which are proportional to the amount of a dose set and delivered by the medication delivery device. The sensing system comprises a first sensor component secured to a first member and a second sensor component secured to a second member. During dose setting, the second member is coupled to a third member which rotates relative to the first member in proportion to the dose set. During dose delivery, the second member is coupled to a fourth member which rotates relative to the first member in proportion to the dose delivered. The sensing system separately detects the relative rotational positions of the first and second sensor components during dose setting and dose delivery, and provides outputs used to determine the amounts of the set and delivered doses. The sensing system outputs this information to a controller which determines the amount of the dose set and delivered ...

DISPENSING MECHANISM FOR A MEDICAL DEVICE

A dispensing mechanism for administering a dosage of a medicament includes dosage setting means (7) for setting the dosage of a medicament to be administered; expelling means (15) for expelling a medicament from a medicament container; and coupling means (21) operatively coupled with the dosage setting means (7) and the expelling means (15), wherein the coupling means (21) is arranged to convert displacement of the dosage setting means (7) into a displacement of the expelling means (15) in a first direction, wherein the expelling means (15) includes a ratchet means (18a, 18b), and wherein the mechanism includes a first and a second independently moveable resisting pawl (14a, 14b) means facing a common side of the ratchet means (18), the first and the second resisting pawl means (14a, 14b) being configured to engage with the ratchet means (18a, 18b) and resist displacement of the expelling means (15) in a second direction opposite to said first direction.

DISPENSING MECHANISM FOR A MEDICAL DEVICE

A dispensing mechanism for administering a dosage of a medicament includes dosage setting means (7) for setting the dosage of a medicament to be administered; expelling means (15) for expelling a medicament from a medicament container; and coupling means (21) operatively coupled with the dosage setting means (7) and the expelling means (15), wherein the coupling means (21) is arranged to convert displacement of the dosage setting means (7) into a displacement of the expelling means (15) in a first direction, wherein the expelling means (15) includes a ratchet means (18a, 18b), and wherein the mechanism includes a first and a second independently moveable resisting pawl (14a, 14b) means facing a common side of the ratchet means (18), the first and the second resisting pawl means (14a, 14b) being configured to engage with the ratchet means (18a, 18b) and resist displacement of the expelling means (15) in a second direction opposite to said first direction.

SYRINGE EXTRUSION ACCESSORY

Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.

AN INJECTION DEVICE WITH ELECTRONIC DETECTING MEANS

An injection device (1) for injecting a dose of drug, e.g. insulin for diabetes treatment, in which energy is stored in a spring member (9, 24) during dose setting. The stored energy is released and used for driving an injection mechanism during injection of a previously set dose. The injection device (1) further comprises means for electronically detecting the amount of a set dose and/or means for electronically detecting the amount of an injected dose. The electronic detecting means allows storage and/or logging of data relating to injections performed using the injection device (1).

ASSEMBLY FOR A DRUG DELIVERY DEVICE

A resettable drive mechanism for a drug delivery device (1) comprises a piston rod assembly (32) and an interaction member (23). The piston rod assembly (32) comprises a guide track (18) running along the piston rod assembly (32), the guide track (18) comprising at least one delivery section (18A) and at least one reset section (18B). The reset section (18B) is arranged to continue the delivery section (18A). The delivery section (18A) comprises at least one blocking means (19). The interaction member (23) is configured to cooperate with the guide track (18). For delivering a dose of a drug (24), the piston rod assembly (32) is axially displaceable in a dose delivery direction away from an axial starting position, the interaction member (23) cooperating with the delivery section (18A) and the blocking means (19) passing the interaction member (23) when the piston rod assembly (32) is displaced in the dose delivery direction. Axial displacement of the piston rod assembly (32) towards the ...

ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE

An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device ...

RESETTABLE DRIVE MECHANISM FOR A MEDICATION DELIVERY DEVICE AND MEDICATION DELIVERY DEVICE

A resettable drive mechanism for a medication delivery device is disclosed, said mechanism comprising a housing (13, 17, 40), a drive member (20) rotatable with respect to the housing in a second direction for delivering a dose of a medication, a piston rod (12) adapted to be driven in a distal direction with respect to the housing by the drive member, when the drive member rotates in the second direction, a stop member (26) adapted to prevent rotation of the drive member in a first direction opposite to the second direction with respect to the housing, when the stop member engages the drive member, and a clutch member (58) movable with respect to the housing between a delivery position (D) and a reset position (R), wherein, when the clutch member is in the delivery position, the stop member and the drive member are engaged and the drive member is prevented from rotating in the first direction with respect to the housing, and when the clutch member is in the reset position, the drive member ...

DRIVE MECHANISM FOR A MEDICATION DELIVERY DEVICE AND MEDICATION DELIVERY DEVICE

A drive mechanism for a medication delivery device (1) is proposed, the drive mechanism comprising a housing (13, 17, 40) having a proximal end and a distal end, a rotation member (21) which is adapted to be rotated in a first direction with respect to the housing during setting of a dose of a medication and to be rotated in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction, a piston rod (12) which is adapted to be displaced in a distal direction with respect to the housing for delivering the dose, a drive member (20) which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member (26) which prevents rotational movement of the drive member with respect to the housing in the first direction during setting of the dose, wherein the rotational movement of the drive member in the second direction is converted into movement of the piston rod in the ...

MEDICATION DISPENSING DEVICE

A medication dispensing device comprising a cartridge for containing an injectable product therein and an injector attached to the cartridge. The injector includes a drive mechanism comprising a dosage sleeve having a dosage knob at the proximal end thereof and a threaded rod coupled to the sleeve and axially advanceable into the cartridge upon clockwise rotation of the knob for dialing up a desired dosage to be injected. A ratchet mechanism is disposed in the injector housing and includes a rotatable piece secured to the dosage sleeve for rotation therewith and a locking seat in engagement with the rotatable piece. The ratchet mechanism permits rotational movement of the sleeve in the clockwise direction only. A disengaging mechanism is secured to the housing of the LCD assembly and includes a pin that extends into and engages the rotatable piece of the ratchet mechanism such that axial movement of the pin causes corresponding axial movement of the stationary piece. Upon depressing the ...

MEDICATION DELIVERY PEN WITH VARIABLE INCREMENT DOSE SCALE

A medication delivery pen is provided having a pen body assembly and a cartridge assembly that are threadedly engageable with one another. The pen bodyassembly includes a rotatable driver for driving a cartridge plunger preselecteddistances that are in accordance with a desired dose of medication to be delivered. The driver providing different preset rates of injection.

OPTICAL DOSE MEASUREMENTS IN SYRINGES

Measurements of insulin quantities in a syringe are performed optically in an integrated insulin dose recorder/blood glucose meter. The syringe (80) is placed in a holder (320) before and after the administration of the dose. Liquid quantities in the syringe are determined by comparing optical response patterns of the syringe with calibration data stored in the device. Dose histories are downloaded to a patient computer for transfer to a clinician's computer. Standard or customized syringes (e.g., with marked plungers) may be used. Other wave energy carriers such as sound waves may also be used.

Display and drug delivery device herewith

특히 인슐린용 자동 어플리케이터를 위한 표시 기구

... 본 발명은 특히 인슐린 또는 다른 액체 제제용, 특히 교체식 용기로부터의 약제의 설정된 투여량의 다중의 주입 투여용, 예를 들어, 당뇨병 환자에 의한 인슐린의 자가-적용을 위한 자동 어플리케이터를 위한 표시 기구에 관한 것이다. 서로 이동가능하게 커플링된 2개 이상의 배럴의 어셈블리를 포함하는 자동 어플리케이터를 위한 표시 기구는 구동 배럴(1) 상에 장착된 표시 배럴(2)이 그 외표면 상에 오직 마킹(2.1)만을 포함하며 풀-푸쉬 조절 너트(3)에 동축으로 연결됨을 특징으로 한다.

특히 인슐린용 자동 어플리케이터를 위한 표시 기구

... 본 발명은 특히 인슐린 또는 다른 액체 제제용, 특히 교체식 용기로부터의 약제의 설정된 투여량의 다중의 주입 투여용, 예를 들어, 당뇨병 환자에 의한 인슐린의 자가-적용을 위한 자동 어플리케이터를 위한 표시 기구에 관한 것이다. 서로 이동가능하게 커플링된 2개 이상의 배럴의 어셈블리를 포함하는 자동 어플리케이터를 위한 표시 기구는 구동 배럴(1) 상에 장착된 표시 배럴(2)이 그 외표면 상에 오직 마킹(2.1)만을 포함하며 풀-푸쉬 조절 너트(3)에 동축으로 연결됨을 특징으로 한다.

DRIVE ASSEMBLY AND USE OF A SPRING IN A DRUG DELIVERY DEVICE

Resettable drive assembly for a drug delivery device is provided for. The resettable drive assembly may comprise a housing (10A, 10B, 10C), a piston rod (20) being rotatable and axially displaceable with respect to the housing between a proximal start position and a distal end position, a drive member (30) for distally displacing the piston rod towards the end position when dispensing a dose, and a stop member (50). The drive member is operable to interact with the piston rod for forming an unlockable first interlock, the first interlock being operable to block proximal movement of the piston rod with respect to the drive member. The stop member is operable to interact with the piston rod for forming an unlockable second interlock, the second interlock being operable to block proximal movement of the piston rod with respect to the housing. When the drive assembly is in a drive mode, the interlocks are locked such that proximal movement of the piston rod from the end position to the start ...

VASCULAR RESISTANCE GAUGE

A system and a method for assessing the patency of a vessel or a graft during coronary artery bypass grafting surgery or PTCA, said system comprising a syringe capable of electronically measuring the pressure and flow of a fluid that is injected into the vessel or graft. The system also comprises a reading device connected to said syringe for displaying flow, pressure and flow resistance parameters.

Inductance-based dose measurement in syringes

Measurements of insulin quantities in a syringe are performed inductively in an integrated insulin dose recorder/blood glucose meter. The syringe is placed in a holder before the administration of the dose, and the liquid quantity in the syringe is recorded. Inductors may be situated within the syringe and/or outside the syringe in various geometries. Standard or customized syringes may be used. Liquid quantities in the syringe are determined by comparing inductive response patterns of the syringe with calibration data stored in the device. Insulin dose and blood glucose histories are downloaded to a patient computer for transfer to a clinician's computer.

DOSE SETTING MECHANISM AND METHOD

An injection device for a dosed administration of an injectable substance and a method of the preparation for the dosed administration, wherein the device includes a toothed rack with a longitudinal length, locking members associated with the rack and locking elements, wherein adjacent locking members have a first separation from each other and the locking elements have a second separation from each other, the first separation being different from the second separation, the method including making a priming movement and a dispensing movement.

A DRUG DELIVERY DEVICE

Stiftförmige Vorrichtung zur Verabreichung von Medikamenten mit unterschiedlich inkrementierter Dosierskala

Berührungslose Abtastung mit magnetoresistivem Sensor

Injektionsgerät zur Verabreichung eines fluiden Produkts mit einer Messeinrichtung zur berührungslosen Messung einer Stellung zwischen relativ zueinander beweglichen Elementen (1; 3) der Verabreichungsvorrichtung, mit welchen eine zu verabreichende Produktdosis eingestellt werden kann, wobei die Messeinrichtung aufweist: a) wenigstens einen magnetoresistiven Sensor (2; 6), der an einem ersten Element (1) befestigt und wenigstens einem relativ zum ersten Element (1) beweglichen zweiten Element (3) gegenüberliegend angeordnet ist, und b) eine magnetische Vorrichtung, die wahlweise oder gleichzeitig gebildet wird aus: – einem Permanentmagneten (11) am ersten Element (1) und wenigstens einem magnetisierbaren zweiten Element (3, 10) und/oder – zumindest einem Permanentmagneten (12) aus mehreren abwechselnd angeordneten unterschiedlichen Magnetpolbereichen (N, S) an wenigstens einem zweiten Element (3).

Injection device

An injection device for injection of set doses of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member. A rotational coupling mechanism includes an axially displaceable coupling member which is rotated as a function of axial displacement. During dose setting, the nut is allowed to rotate relative to the coupling member. During injection, the coupling member is rotationally locked to the nut. This provides a dose setting and injection mechanism wherein the nut member is both rotated during dose setting and during injection.

Injection Device Comprising An Optical Sensor

The present invention relates to an injection device comprising an optically-based sensor for determining the position or setting of a dose setting member arranged to set a dose to be injected from the injection device. In particular, the present invention relates to an injection device comprising a rotatably mounted member having a plurality of optically coded paths arranged on an outer surface thereof. The rotatably mounted member is operatively connected to the dose setting member and is adapted to rotate with the dose setting member.

Resettable Drive Mechanism for a Medication Delivery Device and Medication Delivery Device

A resettable drive mechanism for a medication delivery device is proposed, said mechanism comprising a housing ( 13, 17, 40 ) with a proximal end and a distal end, a drive member ( 20 ) rotatable with respect to the housing in a second direction for delivering a dose of a medication, a piston rod ( 12 ) adapted to be driven in a distal direction with respect to the housing by the drive member, when the drive member rotates in the second direction, a stop member ( 26 ) adapted to prevent rotation of the drive member in a first direction opposite to the second direction with respect to the housing, when the stop member engages the drive member, and a clutch member ( 58 ) movable with respect to the housing between a delivery position (D) and a reset position (R), wherein, when the clutch member is in the delivery position, the stop member and the drive member are engaged and the drive member is prevented from rotating in the first direction with respect to the housing, and when the clutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction with respect to the housing and the piston rod is movable in the proximal direction with respect to the housing. Furthermore, a medication delivery device is provided.

Arrangement for determining a longitudinal position of a stopper

The invention refers to an arrangement and a method for determining a longitudinal position of a stopper for sealing a compartment of a translucent medicament container for a liquid medicament (M). The arrangement comprises a circular light source and a photo sensitive sensor, wherein either the light source or the sensor is laterally arrangeable next to the medicament container extending over at least part of the length of the medicament container, and wherein the respective other of the light source and the sensor is arrangeable in a circular manner around a head of the medicament container. The light source is arranged to emit light into the medicament container. The light is scattered by the medicament or medicament container and detected by the sensor. The sensor is connected to a processor unit for detecting the position of the stopper).

Assembly and Piston Rod for a Drug Delivery Device

A drive mechanism for a drug delivery device ( 1 ) comprises a housing ( 2 ), a drive member ( 5 ) and a piston rod assembly ( 32 ). The drive member ( 5 ) is configured to be axially displaced in a dose setting direction with respect to the housing ( 2 ) for setting a dose of a drug ( 24 ) and to be axially displaced in a dose delivery direction with respect to the housing ( 2 ) for delivering the set dose of the drug ( 24 ). The drive member ( 5 ) comprises a drive feature ( 15 ). The piston rod assembly ( 32 ) comprises a set of interaction surfaces ( 17 ) for mechanical interaction with the drive feature ( 15 ), with at least two interaction surfaces ( 17 ) being axially and angularly offset with respect to each other. When the drive member ( 5 ) is displaced in the dose delivery direction for delivering the set dose, the drive feature ( 15 ) mechanically interacts with one of the interaction surfaces ( 17 ) and the piston rod assembly ( 32 ) rotates with respect to the housing ( 2 ), thereby rotating and axially displacing another one of the interaction surfaces ( 17 ) from a non-interaction position into an interaction position in which the drive feature ( 15 ) may interact with the other one of the interaction surfaces ( 17 ) when the drive mechanism is actuated once more for setting and delivering a further dose. Also, a piston rod ( 3 ) is proposed.

INDICATION MECHANISM FOR AN AUTOMATIC APPLICATOR, PARTICULARLY FOR INSULIN

The present disclosure concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, having an assembly of at least two barrels movably coupled to each other has an indication barrel mounted on the driving barrel contains only marking on its external surface and is co-axially connected to the pull-push control nut. 1. An applicator for administration of set doses of medicine comprising:a housing comprising a driving barrel connected to a mechanism for medicine dose setting,wherein the mechanism for medicine dose setting comprises a plunger,wherein at least a portion of the plunger is surrounded by a rotatable clutch comprising a longitudinal sleeve,wherein the rotatable clutch is coupled to a turning knob,wherein the turning knob is rotatable and substantially axially immovable,wherein at least a portion of the rotatable clutch is surrounded by the helical driving spring and the rotatable clutch extends above the helical driving spring,wherein the helical driving spring is connected to a driving barrel,wherein the driving barrel is rotatable and turned clockwise for increase setting,wherein the rotatable driving barrel surrounds at least a portion of the helical driving spring,wherein the mechanism for medicine dose setting comprises an actuating element used in conjunction with the helical spring,wherein the helical driving spring extends above the driving barrel and is connected to a spring-block member,wherein the spring-block member is connected to the housing and comprises a hollow, a partition and an aperture,wherein the aperture of the spring-block member is at least partially separated from the hollow of the spring-block member by the partition,wherein the hollow of the ...

DOSAGE MEASUREMENT SYSTEM IN A PEN BUTTON

An apparatus includes a pen body of a drug injection pen including a dosage injection mechanism that produces a rotational motion when the drug injection pen dispenses a fluid. The apparatus also includes a button housing with at least part of a dosage measurement system disposed within the button housing. At least part of the dosage measurement system is coupled to receive the rotational motion from the dosage injection mechanism. The dosage measurement system includes one or more sensors positioned to output a signal in response to the rotational motion when the drug injection pen dispenses a fluid, and a controller coupled to the one or more sensors to receive the signal. A drug delivery control wheel of the drug injection pen is disposed between the body of the drug injection pen and the at least part of the dosage measurement system disposed in the button housing. 1. An apparatus , comprising:a pen body of a drug injection pen including a dosage injection mechanism that produces a rotational motion when the drug injection pen dispenses a fluid; one or more sensors positioned to output a signal in response to the rotational motion when the drug injection pen dispenses a fluid; and', 'a controller coupled to the one or more sensors to receive the signal; and, 'a button housing with at least part of a dosage measurement system disposed within the button housing, wherein at least part of the dosage measurement system is coupled to receive the rotational motion from the dosage injection mechanism, the dosage measurement system includinga drug delivery control wheel of the drug injection pen disposed between the body of the drug injection pen and the at least part of the dosage measurement system disposed in the button housing.2. The apparatus of claim 1 , wherein the dosage measurement system irremovably clips into a proximal end claim 1 , opposite the dispensing end claim 1 , of the drug injection pen.3. The apparatus of claim 2 , wherein the button housing is ...

STRAIN BASED DOSAGE MEASUREMENT

A drug injection pen includes a housing shaped to accept a cartridge containing a fluid, and a dosage injection mechanism positioned in the housing to produce a rotational motion and force the fluid out of the cartridge when the drug injection pen dispenses the fluid. A dosage measurement system is disposed in the drug injection pen and is coupled to measure a strain induced in a portion of the dosage measurement system. The dosage measurement system outputs a signal indicative of the strain, and the strain on the portion of the dosage measurement system changes when the dosage injection mechanism dispenses the fluid. The dosage measurement system outputs a signal indicative of the strain when the drug injection pen dispenses the fluid. A controller is coupled to the dosage measurement system, and the controller performs operations including recording the signal output from the dosage measurement system. 1. A drug injection pen , comprising:a housing shaped to accept a cartridge containing a fluid;a dosage injection mechanism positioned in the housing that produces a rotational motion when the drug injection pen dispenses the fluid out of the cartridge;a dosage measurement system disposed in the drug injection pen and coupled to measure a strain induced in a portion of the dosage measurement system, wherein the dosage measurement system outputs a signal indicative of the strain on the portion of the dosage measurement system, and wherein the strain on the portion of the dosage measurement system changes when the dosage injection mechanism dispenses the fluid; and 'recording the signal output from the dosage measurement system.', 'a controller coupled to the dosage measurement system and including logic that when executed by the controller causes the controller to perform operations including2. The drug injection pen of claim 1 , wherein the dosage measurement system includes one or more strain sensors disposed on a flexible component of the dosage measurement system ...

Injection device with torsion spring and rotatable display

The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

Medicine delivery device

Methods, systems, computer-readable media, and apparatuses for facilitating administering of medicine are disclosed.

Medication injector apparatus with drive assembly that facilitates reset

A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen. The injection pen also may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.

Drive mechanism for a medication delivery device and medication delivery device

A drive mechanism for a medication delivery device containing a resilient member and having a rotation member configured to be rotated in a first direction during setting of a dose of a medication and to be rotated in a second direction during delivery of the dose, where the rotation member is coupled to a drive member that is coupled to a piston rod such that on dose delivery the piston rod is displaced in a distal direction to dispense a medicament and where the resilient member prevents movement of the drive member and the piston rod during dose setting.

Assembly for a Drug Delivery Device and Drug Delivery Device

An assembly for a drug delivery device () comprises a housing (), a rotation member (), a drive member () and at least one correction member (). The rotation member () is adapted to be rotated with respect to the housing () in a first rotational direction for delivering a dose of a drug (). The drive member () is coupleable to the rotation member () for delivering the dose. In a delivery mode, the drive member () and the rotation member () are coupled such that the drive member () follows rotational movement of the rotation member () in the first rotational direction due to mechanical interaction of the rotation member () and the drive member (). In a correction mode, the rotation member () and the drive member () are decoupled such that the rotation member () is rotatable in the first rotational direction with respect to the drive member (). For switching from the delivery mode into the correction mode, the correction member () is moveable with respect to the housing (), wherein the assembly is configured such that movement of the correction member () with respect to the housing () is converted into a relative movement between the drive member () and the rotation member () for decoupling the drive member () and the rotation member (). 115-. (canceled)16. An assembly for a drug delivery device , comprising:a housing;a rotation member rotatable with respect to the housing;a drive member rotatable with respect to the housing and coupled to the rotation member by a first unidirectional clutch mechanism; anda first member movable with respect to the housing between a first position and a second position,wherein when the first member is in the first position, the rotation member and the drive member are rotationally coupled anda rotational movement of the rotation member in a first rotational direction causes a rotational movement of the drive member in the first rotational direction for delivering a dose of a drug, andwherein, when the first member is moved from the ...

DRUG DELIVERY SYSTEM AND METHOD

An insulin delivery system and method for dispensing a measured, user selected, amount of insulin, a derivate thereof, or another substance into an animal via a dosing module and a delivery module. The system includes a reusable dosing module. The reusable dosing module is adapted to extract a set volume of the insulin, a derivate thereof, or another substance and a set volume of the diluent from reservoir(s). The reservoir(s) optionally includes a vial, and transfers the set volume(s) to a single use, manually activated injector reservoir. The reusable injector carrier module is configured to house the single use manually activated injector reservoir and configured to provide a surface to stroke or calm the animal prior to injection. 1. A fluid delivery system for dispensing a measured , pre-selected amount of a drug to a target , comprising:(a) a reusable dosing module the reusable dosing module being adapted to extract a set amount of the drug from a first reservoir, the first reservoir optionally comprising a first vial, and being adapted to extract a set volume of diluent from a second reservoir, the second reservoir optionally comprising a second vial, and transfer the selected, set volume(s) to a single use, manually activated injector reservoir, the injector reservoir being removably housed in a cavity of a housing of the reusable dosing module, and 'whereby the system is adapted to provide for user selected therapeutic dosing of the measured amount of the fluid and user selected amount of diluent.', '(b) a reusable injector carrier assembly configured to house the single use manually activated injector reservoir and configured to provide a smooth surface to stroke or calm an animal target prior to fluid delivery, and a cavity adapted for removably housing the single use manually activated injector reservoir,'}2. The fluid delivery system of claim 1 , wherein the target is an animal claim 1 , and the dispensing of the fluid is intended to be performed ...

MINI SYRINGE

A mini syringe includes a tubular base member, a microneedle unit including a microneedle device and a compressible pharmacy housing device and mounted in the bottom side of the base member, a plunger mounted in the base member and pressable to compress the pharmacy housing device, and an adjustment cover threaded onto the base member for controlling the moving distance of the plunger in a micro-adjustable manner. 1. A mini syringe , comprising:a base member comprising a center hole, a flange extended around a bottom side thereof, and an outer thread spirally extended around the periphery thereof;a microneedle unit is mounted in a bottom end of said center hole of said base member and consisting of a microneedle device and a pharmacy housing device, said microneedle device comprises at least one microneedle, said pharmacy housing device comprising at least one drug chamber respectively disposed corresponding to said at least one microneedle;a plunger mounted in an opposite top end of said center hole of said base member, said plunger comprising a plunger body axially slidably inserted into said center hole of said base member, a reduced outer diameter portion upwardly extended from a top side of said plunger body and at least one plunger tip aimed at said at least one drug chamber;an adjustment cover comprising an inner thread threaded onto said outer thread of said base member and a through hole for the passing of said reduced outer diameter portion of said plunger; anda spacer ring mounted between a bottom side of said adjustment cover and said flange of said base member.2. The mini syringe as claimed in claim 1 , wherein said microneedle device comprises a base panel and at least one microneedle; said pharmacy housing device comprises at least one drug chamber corresponding to said at least one microneedle.3. The mini syringe as claimed in claim 1 , wherein said plunger body of said plunger body fits said center hole of said base member and is axially movable ...

Drug Delivery Device

A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a track comprising a sequence of encoded images; and a sensor directed at the track of the cylindrical member and configured to detect features of the encoded images.

ELECTRONIC INJECTOR FOR INJECTING A MEDICINAL PRODUCT

An example injector includes a rotary knob for selecting a function and setting a dosing quantity for an injection, a button located on an end of the rotary knob for initiating the injection, an electric motor, an encoder for evaluating output rotary motion of the motor, and a processor that converts the dosing quantity into a number of encoder pulses and controls operation of the motor based on the number of encoder pulses when dosage is triggered. The injector also includes a transmission coupled to the electric motor to convert a speed of the motor, a threaded spindle coupled to the transmission that moves linearly based on the output rotary motion of the motor at the speed as converted by the transmission, and a punch connected to an end of the threaded spindle. The linear movement of the spindle causes the punch to release medicament. 1. An injector comprising: a gear wheel;', 'an internal spindle coupled to the gear wheel, wherein the internal spindle is threaded along a length of the internal spindle;', 'an inner sleeve, wherein the inner sleeve includes internal threads for mating with threads of the internal spindle for positioning the internal spindle into the inner sleeve, and wherein the inner sleeve includes external threads;', 'a spindle nut, wherein the spindle nut includes internal threads for mating with the external threads of the inner sleeve for positioning the inner sleeve into the spindle nut; and', 'an outer sleeve into which the spindle nut, the inner sleeve, and the internal spindle are positioned in a retracted state, wherein the outer sleeve includes an anti-rotation component,', extending the spindle nut away from the outer sleeve until the spindle nut meets an end of the inner sleeve via rotation of the internal spindle and the inner sleeve; and', 'then extending the inner sleeve away from the internal spindle, thereby pushing the spindle nut and the outer sleeve forward., 'wherein rotation of the gear wheel in a first direction causes ...

DETERMINATION OF A DOSE SET AND DELIVERED IN A MEDICATION DELIVERY DEVICE

Sensing systems are disclosed for determining the relative rotational movements of members of a medication delivery device which are proportional to the amount of a dose set and delivered by the medication delivery device. The sensing system comprises a first sensor component secured to a first member and a second sensor component secured to a second member. During dose setting, the second member is coupled to a third member which rotates relative to the first member in proportion to the dose set. During dose delivery, the second member is coupled to a fourth member which rotates relative to the first member in proportion to the dose delivered. The sensing system separately detects the relative rotational positions of the first and second sensor components during dose setting and dose delivery, and provides outputs used to determine the amounts of the set and delivered doses. The sensing system outputs this information to a controller which determines the amount of the dose set and delivered. Related medication delivery devices and methods are also disclosed. 1. A sensing system for determining both the amount of a dose set and the amount of a dose delivered by operation of a medication delivery device , the sensing system comprising:a first member of the medication delivery device;a second member of the medication delivery device, the second member being rotatable relative to the first member;a third member of the medication delivery device rotatable relative to the first member during dose setting in proportion to the amount of a dose set by operation of the medication delivery device;a fourth member of the medication delivery device rotatable relative to the first member during dose delivery in proportion to the amount of a dose delivered by operation of the medication delivery device;the second member being rotationally coupled with the third member and not the fourth member during dose setting to rotate with the third member during dose setting, the second ...

WEIGHT-BASED DOSING SYRINGE

A system includes a syringe barrel, a syringe plunger, and an annular collar. The syringe barrel has a longitudinal axis aligned axially between a discharge end and a cylinder end. The syringe plunger has a cap disposed on a first end, a piston disposed on a second end and configured for disposition in a bore of the barrel, and has a body disposed between the first end and the second end. The body has an external thread on a first surface and the body has a visible calibration indication aligned axially. The annular collar has at least one interrupted internal thread segment on an interior surface. The collar has elasticity such that in a first state, the internal thread is configured to engage the external thread and in a second state, in which a compressive force is exerted on opposing sides of the collar, the internal thread is disengaged from the external thread. 1. A system comprising:a syringe barrel having a longitudinal axis aligned axially between a discharge end and a cylinder end;a syringe plunger having a cap disposed on a first end, a piston disposed on a second end and configured for disposition in a bore of the barrel, and having a body disposed between the first end and the second end, the body having an external thread on a first surface and the body having a visible calibration indication aligned axially; andan annular collar having at least one interrupted internal thread segment on an interior surface, the collar having elasticity such that in a first state, the internal thread is configured to engage the external thread and in a second state, in which a compressive force is exerted on opposing sides of the collar, the internal thread is disengaged from the external thread.2. The system of wherein the external thread is discontinuous and disposed on a face of the body.3. The system of wherein the calibration indication is disposed in a recess of the body.4. The system of wherein the calibration indication includes a color coding associated with ...

DOSE MEASURING DEVICE FOR DRUG DELIVERY DEVICE

A dose measuring device for a drug delivery device is provided. The dose measuring device includes a main body and a dial sleeve coupled to the main body to spirally move, the dose measuring device including a housing provided to be removable from the main body, a rotation ring received in the housing to rotate, an encoder installed in the housing to detect the amount of rotation of the rotation ring, and an auxiliary sleeve provided to be removable from the dial sleeve and to spirally move together with the dial sleeve in the housing, in which the rotation ring is bound to the auxiliary sleeve to rotate together with the auxiliary sleeve and is fixed in the housing in a longitudinal direction of the main body. 1. A dose measuring device for a drug delivery device that comprises a main body and a dial sleeve coupled to the main body to spirally move , the dose measuring device comprising:a housing arranged to receive the main body of the drug delivery device;a rotation ring arranged in the housing to rotate;an encoder installed in the housing to detect an amount of rotation of the rotation ring; andan auxiliary sleeve arranged to be removable from the dial sleeve of the drug delivery device and to spirally move together with the dial sleeve in the housing, wherein the rotation ring is bound to the auxiliary sleeve to rotate together with the auxiliary sleeve and is fixed in the housing in a longitudinal direction of the main body.2. The dose measuring device of claim 1 , wherein the drug delivery device is inserted into the housing from a side of the housing in the longitudinal direction of the main body claim 1 , such that an end portion of the dial sleeve is bound to an inner side of the auxiliary sleeve and the housing is bound onto the main body.3. The dose measuring device of claim 1 ,wherein the auxiliary sleeve spirally moves together with the dial sleeve while binding protrusions formed on an outer circumferential surface of the dial sleeve are engaged to an ...

DOSE SETTING DEVICE FOR AN INJECTION DEVICE

A dosing device for an injection device, the dosing device including an actuating element for adjusting and/or dispensing a dose from the injection device, a thrust element for generating a forward movement for discharging a dose and a coupling to which the actuating element and the thrust element are coupled such that a rotational movement of the actuating element is transmitted directly to the thrust element and an axial movement of the actuating element is different than an axial movement of the thrust element. 1. An injection device comprising a dose setting device and an ampoule containing a substance , said dose setting device comprising:a housing;an operating element in threaded engagement with the housing and rotatable to move in a proximal direction for setting a dose;a threaded rod which is threadedly engaged with an internal thread of the housing and which can be moved to dispense the substance from the injection device;a restrictor element for limiting the setting of a maximum total dose to be set and which is coupled to the operating element so that a setting movement for dose increase or correction is converted into a movement of the restrictor element in the proximal or distal direction of the injection device;a lock element which prevents rotation of the threaded rod in one rotation direction and enables rotation of the threaded rod such that it can be screwed in the distal direction only, whereby during dispensing the lock element rotates relative to the housing to produce dispensing clicking noises,said lock element being coupled to the restrictor element so that the lock element is prevented from moving axially relative to the restrictor element but the lock element and the restrictor element can be rotated freely relative to one another via a dose clicking mechanism, whereby during dose setting the relative rotation produces dose clicking noises and during dispensing the lock element and the restrictor element rotate in unison and produce no dose ...

Assembly For A Drug Delivery Device

An assembly for a drug delivery device ( 1 ), comprises a housing ( 2 ), a dose member ( 22 ), a guide track ( 42 ) and a spring member ( 26 ). The dose member ( 22 ) is adapted to be rotated in a dose setting direction with respect to the housing ( 2 ) for setting a dose of a drug ( 5 ) and to be rotated in a dose delivery direction with respect to the housing ( 2 ) for delivering the set dose. The dose member ( 22 ) comprises a guide feature ( 46 ). The guide track ( 42 ) is configured to mechanically cooperate with the guide feature ( 46 ). The guide track ( 42 ) comprises a first section ( 43 A) and a second section ( 43 B) which are connected to each other via a connection region ( 55 ). The first section ( 43 A) defines an angular start position ( 54 ) for the guide feature ( 46 ) and the second section ( 43 B) defines an axial stop position ( 56 ) for the guide feature ( 46 ). When the dose member ( 22 ) is rotated in the dose setting direction, the guide feature ( 46 ) is angularly displaced from the angular start position ( 54 ) towards the connection region ( 55 ), the spring member ( 26 ) is torsionally biased, the biased spring member ( 26 ) tending to angularly displace the guide feature ( 46 ) towards the angular start position ( 54 ). When the guide feature ( 46 ) has passed the connection region ( 55 ), the guide feature ( 46 ) enters the second section ( 43 B) and is axially displaced in a proximal direction with respect to the housing ( 2 ) towards the axial stop position ( 56 ). In the axial stop position, reduction of the torsional bias is prevented by mechanical cooperation of the guide feature ( 46 ) and the second section ( 43 B).

ACCESSORY DEVICE WITH ZERO POSITION ADJUSTMENT FEATURE

An add-on device configured to be releasably attached to a drug delivery device comprising a housing with a reference marker and a scale drum with a zero identifier and an initial marker. The add-on device comprises a memory and a camera adapted to capture an image of the housing reference marker and the initial marker when the scale drum is in a (near) initial position. The add-on device is adapted to perform a reference offset value determination, comprising: capture an image, perform an image analysis to determine if the captured image comprises the zero identifier, if so, determine a reference offset value based on the distance between the housing reference marker and the initial marker, the reference off-set value representing the initial rotational position, and if no reference offset value is stored in the memory or if the determined reference offset value corresponds to a smaller set dose amount than a currently stored value, store in the memory the determined reference offset value. 1. An add-on device configured to be releasably attached to a given drug delivery device , the drug delivery device comprising:a drug reservoir or a compartment for receiving a drug reservoir,drug expelling structure comprising a dose setting member allowing a user to set a dose amount of drug to be expelled,an indicator member adapted to rotate relative to the housing during dose setting and dose expelling corresponding to an axis of rotation, the amount of rotation corresponding to a set dose respectively the amount of drug remaining to be expelled from a reservoir by the expelling structure, the indicator member having an initial rotational position corresponding to no dose amount being set,a housing comprising an opening allowing a user to observe a portion of the indicator member, the opening being surrounded by an edge formed by the housing, the housing comprising a housing reference marker, a plurality of indicia, the currently observable indicia indicating to a user the ...

SYRINGE EXTRUSION ACCESSORY

Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one pawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe. 1. A syringe extrusion accessory comprising:a handle operatively coupled to an attachment portion configured to attach to a syringe; andat least one pawl operatively coupled to the handle and configured to engage with a plunger of the syringe,wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.2. The syringe extrusion accessory of claim 1 , wherein the at least one pawl includes at least one claw.3. The syringe extrusion accessory of claim 1 , wherein the pawl has a sinusoidal shape.4. The syringe extrusion accessory of claim 1 , wherein the handle is coupled to the attachment portion through a hinge.5. The syringe extrusion accessory of claim 1 , wherein the pawl is coupled to the handle through a hinge.6. The syringe extrusion accessory of claim 5 , wherein the pawl is further attached to the handle with a spring.7. The syringe extrusion accessory of claim 6 , wherein the spring is a compression spring.8. The syringe extrusion accessory of claim 1 , wherein the substantially perpendicular force is between about 1 degree and about 20 degrees perpendicular to the syringe.9. The syringe extrusion accessory of claim 1 , wherein the attachment portion is configured to attach to a flange portion of the syringe.10. The syringe extrusion accessory of claim 1 , wherein the handle includes a depression configured to apply force from at least one finger.11. A method of ...

DRUG DELIVERY SYSTEM WITH MULTIPOLAR MAGNET AND SENSOR SYSTEM

A drug delivery system comprises an indicator element and a sensor system. The indicator element is arranged to rotate relative to a reference component and corresponding to a reference axis and comprises a plurality of dipole magnets. The sensor system comprises a plurality of magnetometers arranged non-rotational relative to the reference component and adapted to determine continuous magnetic field values from the plurality of dipole magnets, as well as processor means configured to determine on the basis of measured values from the plurality of magnetometers a rotational position and/or a rotational movement of the indicator element. 2. The dose detection system as in claim 1 , wherein the medication delivery device further comprises:drug expelling structure comprising a rotatable dose setting member allowing a user to set a dose amount of drug to be expelled,the electronics assembly being adapted to engage the dose setting member allowing a user to set a dose amount of drug to be expelled via the electronics assembly.3. The dose detection system as in claim 1 , wherein the magnetic sensors are arranged in a plane perpendicular to the rotational axis of the magnetic ring.4. The dose detection system as in claim 1 , wherein the magnetic sensors are arranged with circularly equal spacing.5. The dose detection system as in claim 1 , comprising 4 claim 1 , 5 claim 1 , 6 claim 1 , 7 or 8 magnetic sensors arranged in a circular pattern.6. The dose detection system as in claim 1 , wherein the magnetic sensors are arranged distally in the electronics assembly facing the magnetic ring in a mounted position.7. The dose detection system as in claim 1 , wherein the rotational position and/or a rotational movement of the magnetic ring is determined using a DFT algorithm.9. The add-on device as in claim 8 , wherein the drug delivery device further comprises:drug expelling structure comprising a rotatable dose setting member allowing a user to set a dose amount of drug to be ...

DRUG DELIVERY DEVICE

Drug delivery device comprising a housing retaining a primary drug delivery assembly for the delivery of a primary medicament with a primary dose setting member configured to rotate in a helical movement to set a dose of the primary medicament and a secondary drug delivery assembly for the delivery of a secondary medicament. A dose dial is movable between a first position and a second position in axial direction and is rotationally constrained with respect to the housing when moved from the first position into the second position and is rotationally constrained to the primary dose setting member in the second position. A dispense actuator moves in distal direction to initiate dispense of the secondary medicament. The dose dial and the dispense actuator can be coupled via a clutch component for dispense of the secondary medicament.

Housing for a drug delivery device and drug delivery device

The invention is directed to a housing () for a drug delivery device comprising a first receiving section () for retaining a primary drug delivery assembly () and a second receiving section () for retaining a secondary drug delivery assembly (). A movable actuator () comprises a first engagement section () and an actuation collar () comprises a second engagement section (). A setting element () is movable around a second longitudinal axis () from a first position into a second position during a setting movement () and drives the actuation collar () into engagement with the actuator (), wherein in the first position of the setting element () the actuator () is free to move relative to the actuation collar () and in the second position of the setting element () the actuation collar () engages the actuator () such that an actuation movement () of the actuator () is transferred to the actuation collar (). The invention is also directed to a respective drug delivery device. 17. A housing () for a drug delivery device comprising:{'b': 14', '16', '15', '17, 'a first receiving section () for retaining a primary drug delivery assembly () and a second receiving section () for retaining a secondary drug delivery assembly ();'}{'b': 34', '4', '55, 'an actuator () arranged such that it is movable along a first longitudinal axis () and comprising a first engagement section ();'}{'b': 35', '15', '37', '53, 'a preferably lever actuatable setting element () located in the second receiving section () and an actuation collar () comprising a second engagement section (),'}{'b': 35', '5', '56', '35', '37', '34', '56', '35', '34', '37', '35', '37', '34', '63', '34', '37, 'wherein the setting element () is movable around a second longitudinal axis () from a first position into a second position during a setting movement (), wherein the setting element () drives the actuation collar () into engagement with the actuator () during the setting movement (), wherein in the first position of the ...

Assembly for a Drug Delivery Device and Drug Delivery Device

An assembly for a drug delivery device () is proposed, comprising a housing () having a proximal end and a distal end, a dose member () which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member () which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member () configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, 115-. (canceled)16. An assembly for a drug delivery device , comprising:a housing having a proximal end and a distal end;a dose member which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug;a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose; anda stop member configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing,wherein the dose member is threadedly connected to the housing or a housing insert and wherein the dose member is rotated in a first direction with respect to the housing and displaced in the proximal direction with respect to the housing for setting of the dose;wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose, andwherein during mechanical cooperation of the dose member and the clutch member when the clutch member is in the clutch stop ...

Injection Device Comprising an Optical Sensor

The present invention relates to an injection device comprising an optically-based sensor for determining the position or setting of a dose setting member arranged to set a dose to be injected from the injection device. In particular, the present invention relates to an injection device comprising a rotatably mounted member having a plurality of optically coded paths arranged on an outer surface thereof. The rotatably mounted member is operatively connected to the dose setting member and is adapted to rotate with the dose setting member. 1. A method for determining the position or setting of a dose setting member adapted to set a dose of a medicament to be injected from an injection device comprising a dose setting member , the dose setting member being operatively connected to a rotatably mounted member , the method comprising:projecting a plurality of light beams onto a plurality of optically coded tracks provided on an outer surface of a rotatably mounted member adapted to set a dose of medicament to be injected from an injection device, the optically coded tracks being arranged as parallel helically extending tracks on the rotatably mounted member, anddetecting light intensities of a plurality of light beams reflected from the optically coded tracks, anddetermining the position or setting of the dose setting member from the detected intensities.2. The method according to claim 1 , wherein the number of light beams equals the number of optically coded tracks provided on the rotatably mounted member.3. The method according to claim 1 , wherein the intensity of the plurality of optical light beams varies in accordance with the position of the dose setting member in that the reflectivity or transparency of the outer surface of the rotatably mounted member varies along the optically coded tracks.4. The method according to claim 1 , wherein the number of light beams projected onto the outer surface of the rotatably mounted member and the number of light beams ...

INJECTOR APPARATUS HAVING A CLUTCH TO INHIBIT FORWARD MOVEMENT OF THE PLUNGER

An injector apparatus includes a housing () for a cartridge or syringe, a plunger () for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement () to select a dose volume, and a drive mechanism () releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring () for imparting movement directly or indirectly to the plunger (), and the dose setting arrangement includes a dose setting element () moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement () operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring. 1. An injector apparatus for use with a cartridge or syringe to deliver a plurality of doses therefrom , the injector apparatus comprising:{'b': 10', '10, 'sup': 1', '2, 'a housing (, ) for the cartridge or syringe;'}{'b': '40', 'a plunger () for cooperating with the cartridge or syringe to express successive doses;'}{'b': 22', '24', '22', '16, 'a drive mechanism (, ) energised by a drive spring (), and releasable to advance said plunger in predetermined increments as determined by adjustment of a dose setting element (); and'}{'b': 70', '24', '16, 'a re-energising element () for re-energising said spring () independently of movement of said dose setting element ().'}2. The injection apparatus according to claim 1 , wherein said drive spring is a torsion spring and said re-energising element is a rotary element.3. The injection apparatus according to claim 2 , wherein said rotary re-energising element is mounted for rotary movement in one direction on said housing by a ratchet arrangement. This invention relates to injector apparatus and in particular, but not exclusively, to such apparatus used ...

ACTUATION MECHANISM

An actuation mechanism is presented for a medicament delivery device having a plunger rod arranged to act on a stopper of a medicament container, an actuator arranged slidable and connected to the plunger rod for acting on the stopper when said actuator is operated by displacing it in a longitudinal direction of the actuation mechanism, and an activator for activating the actuation mechanism and for setting a dose. The activator having a generally tubular activator sleeve provided with a spirally extending groove on an outer surface, the groove arranged with a length corresponding to the total amount of medicament to be delivered in a number of doses contained in said medicament container, where the groove is provided with an end wall, a stop ring arranged coaxial with said activator sleeve. The activator sleeve arranged with a follower positioned in the groove and the follower arranged to abut the end wall when the total amount has been delivered. 112-. (canceled)13: An actuation mechanism to be used with a medicament delivery device , the actuation mechanism comprising:a plunger rod arranged to act on a stopper of a medicament container;an actuator arranged slidable and connected to the plunger rod for acting on the stopper when said actuator is operated by displacing it in a longitudinal direction of the actuation mechanism;an activator rotatably arranged for activating said actuation mechanism and for setting a medicament dose;said activator comprising a generally tubular activator sleeve provided with a spirally extending groove on its outer surface,said groove arranged with a length corresponding to a total amount of medicament to be delivered in a number of doses contained in said medicament container,said groove provided with an end wall,a stop ring arranged coaxial with said activator sleeve;said activator sleeve arranged with a follower positioned in said groove, wherein said follower is arranged to abut said end wall of said groove when said total amount ...

Assembly for a Drug Delivery Device and Drug Delivery Device

An assembly for a drug delivery device () comprises a housing (), a rotation member (), a drive member () and at least one correction member (). The rotation member () is adapted to be rotated with respect to the housing () in a first rotational direction for delivering a dose of a drug (). The drive member () is coupleable to the rotation member () for delivering the dose. In a delivery mode, the drive member () and the rotation member () are coupled such that the drive member () follows rotational movement of the rotation member () in the first rotational direction due to mechanical interaction of the rotation member () and the drive member (). In a correction mode, the rotation member () and the drive member () are decoupled such that the rotation member () is rotatable in the first rotational direction with respect to the drive member (). For switching from the delivery mode into the correction mode, the correction member () is moveable with respect to the housing (), wherein the assembly is configured such that movement of the correction member () with respect to the housing () is converted into a relative movement between the drive member () and the rotation member () for decoupling the drive member () and the rotation member (). 115-. (canceled)16. An assembly for a drug delivery device , the assembly comprising:a housing;a rotation member rotatable with respect to the housing;a drive member rotatable with respect to the housing; anda unidirectional clutch mechanism coupling the drive member and the rotation member, wherein:in a first position, the unidirectional clutch mechanism rotationally couples the rotation member and the drive member such that a rotational movement of the rotation member in a first rotational direction causes a rotational movement of the drive member in the first rotational direction,in a second position different from the first position, the unidirectional clutch mechanism uncouples the rotation member and the drive member such that ...

Colored Seal System, Method, and Apparatus

A colored seal system, method, and apparatus. The colored seal system includes a barrel having a delivery end and an open end. The barrel includes multiple markings. The barrel markings include at least measurements and multiple fill indicators. The colored seal system includes a colored seal slidably positioned within the barrel for moving a delivery agent. The colored seal is visible within at least one of the fill indicators. 1. A colored seal system , comprising:a barrel including a delivery end and an open end, the barrel including a plurality of barrel markings, wherein the barrel markings include at least measurements and a plurality of fill indicators; anda colored seal slidably positioned within the barrel for moving a delivery agent, wherein the colored seal is visible within at least one of the fill indicators.2. The colored seal system of claim 1 , wherein the colored seal is connected to a plunger for moving the colored seal within the barrel to insert and remove the delivery agent.3. The colored seal system of claim 1 , wherein the barrel is transparent or semi-transparent claim 1 , and wherein the colored seal is fluorescent.4. The colored seal system of claim 1 , wherein the measurements include line markings and numeric markings.5. The colored seal system of claim 1 , wherein the fill indicators correspond to fill levels for the numeric markings.6. The colored seal system of claim 1 , wherein the plurality of fill indicators are hollow shapes.7. The colored seal system of claim 6 , wherein the plurality of fill indicators are circles.8. The colored seal system of claim 1 , wherein the plurality of fill indicators are one or more of a square claim 1 , triangle claim 1 , oval claim 1 , star claim 1 , octagon claim 1 , hexagon claim 1 , and rectangle.9. The colored seal system of claim 1 , wherein a size of a front bevel of the colored seal within the barrel corresponds to a size of the plurality of fill indicators.10. The colored seal system of claim ...

Injection Device

The present disclosure relates to an injection device for delivery of a liquid medicament including a housing, a cartridge having a tubular shaped barrel filled with a liquid medicament and sealed in a proximal direction by a piston displaceably arranged in the barrel, and a drive mechanism having a piston rod to advance in a distal direction against a proximally facing surface of the piston of the cartridge. The drive mechanism is configured to advance the piston rod in the distal direction by a distance z1 to dispense a reference volume V1 of the medicament when operably engaged with a reference cartridge having a reference diameter D1, and, the cartridge has a diameter D2 smaller than the reference diameter D1 to dispense a volume V2 of the medicament smaller than the reference volume V1 when the piston rod advances in distal direction by the distance z1.

High Precision Syringe with Removable Pump Unit

A digital syringe is used with conventional polymer disposable syringe construction to be practical in the medical environment. Errors associated with the larger volumes of the syringes (which exacerbate minor errors in plunger position) and the flexibility and dimensional variations of the polymer plungers are accommodated by direct measurement of the syringe plunger position rather than indirect measurement of motor position and inference of syringe plunger position. This direct measurement eliminates mechanical tolerances (“stack up”) in the motor, gear train, and lead screw on plunger movement, an effect exacerbated by flexibility of the plunger and changes in syringe resistance and medicament viscosity, for example, with different medicaments or when the syringe is refrigerated. The digital syringe may be combined with the motor unit to provide additional versatility.

Syringe extrusion accessory

Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.

ADMINISTRATION INSTRUMENT FOR MEDICAL USE

An administration instrument includes an injection button which can be pressed at an angle that is not parallel to a needle with respect to a direction in which the needle is inserted into skin. As a result, it is possible to prevent a force of pressing the injection button from being transmitted in the direction in which the needle is inserted into the skin deeper than initial insertion of the needle, thereby achieving an administration under a stable state.

Assembly for a Drug Delivery Device and Drug Delivery Device

An assembly for a drug delivery device comprises a housing, a dose member which is displaceable in a proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position. The clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. 115-. (canceled)16. An assembly for a drug delivery device , the assembly comprising:a housing having a proximal end and a distal end;a dose member configured to be displaced in a proximal direction with respect to the housing during setting of a dose of a drug;a clutch member configured to be displaced in a proximal direction with respect to the housing during setting of the dose; anda stop member configured to stop a proximal displacement of the clutch member with respect to the housing, wherein the clutch member, when in a clutch stop position, abuts the stop member and is prevented from being further displaced in the proximal direction with respect to the housing,wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position to prevent further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose, andwherein a clutch spring member is configured to prevent the dose member from cooperating mechanically with the clutch member when the clutch member is out of the clutch stop position.17. The assembly according to claim 16 , wherein the clutch spring member is configured to bias the dose member and the clutch member away from one another.18. The assembly according to claim 16 , ...

Colored Seal System

A colored seal system, method, and apparatus. A barrel includes barrel markings including at least numeric measurements and fill indicators. The fill indicators define open space enclosed by the fill indicators. The colored seal system includes a colored seal slidably positioned within the barrel for moving a delivery agent. The colored seal is visible within at least one of the fill indicators.

Assembly for a Drug Delivery Device and Drug Delivery Device

An assembly for a drug delivery device comprises a housing, a dose member which is displaceable in a proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position. The clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. 1. (canceled)2. A drug delivery device comprising:a housing;an insert member axially and rotationally fixed relative to the housing;a dose member threadedly connected to the insert, the dose member configured to rotate in a first direction and translate proximally relative to the housing and the insert member while a dose is being dialed up and to rotate in a second direction and translate distally relative to the housing and the insert member while the dose is being delivered;a clutch member connected to the dose member such that the clutch member moves proximally with the dose member and does not rotate relative to the housing and the insert member while the dose is being dialed up and moves distally with the dose member while the dose is being delivered;a stop member; anda spring member disposed in a notch of the clutch member, the spring member being in a deformed state when the clutch member is in a clutch stop position,wherein the dose member cannot rotate relative to the clutch member in the first direction and can rotate relative to the clutch member in a second direction opposite the first direction when the clutch member is in the clutch stop position, and the dose member can rotate relative to the clutch member in the first direction and in the second direction when the clutch member is out of the clutch stop position.3 ...

Piston washer assembly, method of assembly and drug delivery device incorporating such piston washer assembly

The present invention relates to a piston washer assembly (100, 100′) for use in a drug delivery device for transferring a distally directed axial force from a piston rod (220) towards a piston (214) of a held cartridge (213). The piston washer assembly (100, 100′) comprises a) a proximal part (110, 110′) adapted for engagement with the distal portion of a piston rod (220), the proximal part (110, 110′) defining a first set of cooperating geometries (115, 115′), and b) a distal part (120, 120′) configured to engage and abut a piston (214) of a held cartridge (213) and to engage the proximal part (110, 110′), wherein the distal part (120, 120′) defines a second set of cooperating geometries (125, 125′) engaging the first set of cooperating geometries (115, 115′). In an initial state of the assembly, the proximal part (110, 110′) and the distal part (120, 120′) are positioned relatively to each other to define an initial axial dimension (H1) for the assembly. The first set of cooperating geometries (115, 115′) and the second set of cooperating geometries (125, 125′) are configured to enable relative movement for increasing the axial dimension for obtaining a target axial dimension (H2) but preventing a decrease in axial dimension. The invention further relates to a drug delivery device, a method of assembling a drug delivery device incorporating such piston washer assembly and a method of preparing a piston washer assembly.

DRUG DELIVERY DEVICE WITH ZERO POSITION ADJUSTMENT FEATURE

A method of manufacturing a pen drug delivery device comprising the steps of (i) providing a drug delivery device comprising a dose indicator member adapted to move relative to a housing during dose setting and dose expelling corresponding to an axis of rotation, the indicator member having an initial position corresponding to no dose amount being set, (ii) arranging the indicator member in the initial rotational position, and (iii) providing on the housing and on the indicator member respectively a pair of zero markers having a predetermined rotational offset. By this arrangement the issue of finding the correct initial (zero) rotational position of the indicator member is addressed by providing corresponding and rotationally paired zero markings on the pen housing and the indicator member after the pen device has been assembled, this allowing the “true” initial position to be detected by image capture and subsequent image analysis. 1. A method of manufacturing a drug delivery device , comprising the steps of: a drug reservoir or a compartment for receiving a drug reservoir,', 'drug expelling structure comprising a dose setting member allowing a user to set a dose amount of drug to be expelled,', 'an indicator member adapted to rotate relative to the housing during dose setting and dose expelling corresponding to an axis of rotation, the amount of rotation corresponding to a set dose respectively the amount of drug remaining to be expelled from a reservoir by the expelling structure, the indicator member having an initial rotational position corresponding to no dose amount being set,', 'a housing comprising a window allowing a user to observe a portion of the indicator member, the window being surrounded by an edge portion formed by the housing,', 'a pattern arranged circumferentially or helically on the indicator member and comprising a plurality of indicia, the currently observable indicia indicating to a user the size of a currently set dose amount of drug to be ...

Pen Type Drug Injection Device with Absolute Angular Dose Encoder Mechanism

A drug delivery device comprising: a housing; a cylindrical member rotatably supported within the housing; and a plurality of sensors; wherein: the outer surface of the cylindrical member is provided with a single track, the track forming an encoder and having a plurality of first track segments and a plurality of second track segments arranged along the length of the track which are respectively capable of inducing first and second responses in the sensors; and in each rotational position of the cylindrical member relative to the housing at least one different first track segment is capable of inducing a first response in at least one said sensor, thereby enabling the rotational position of the cylindrical member relative to the housing to be determined. 114.-. (canceled)15. A drug delivery device comprising:a housing;a cylindrical member rotatably supported within the housing;a plurality of optical sensors;a sleeve which surrounds at least part of said cylindrical member and which rotates relative to the optical sensors in one operational mode of the device but not in another operational mode of the device; andan additional optical sensor for monitoring the rotational position of opaque markings provided on the sleeve in order to determine the mode of operation of the device;wherein the outer surface of the cylindrical member is provided with a single track, the track forming an encoder and having a plurality of first track segments and a plurality of second track segments arranged along the length of the track, the first and second track segments respectively comprising differently marked parts of the track; andwherein in each rotational position of the cylindrical member relative to the housing at least one different first track segment is capable of inducing a first response in at least one of the optical sensors, thereby enabling the rotational position of the cylindrical member relative to the housing to be determined.16. The device of claim 15 , further ...

DRUG DELIVERY SYSTEM WITH MULTIPOLAR MAGNET AND SENSOR SYSTEM

A drug delivery system comprises an indicator element and a sensor system. The indicator element is arranged to rotate relative to a reference component and corresponding to a reference axis and comprises a plurality of dipole magnets. The sensor system comprises a plurality of magnetometers arranged non-rotational relative to the reference component and adapted to determine continuous magnetic field values from the plurality of dipole magnets, as well as processor means configured to determine on the basis of measured values from the plurality of magnetometers a rotational position and/or a rotational movement of the indicator element. 2. The dose detection system as in claim 1 , wherein the medication delivery device further comprises:drug expelling structure comprising a rotatable dose setting member allowing a user to seta dose amount of drug to be expelled,the electronics assembly being adapted to engage the dose setting member allowing a user to set a dose amount of drug to be expelled via the electronics assembly.3. The dose detection system as in claim 1 , wherein the magnet ring comprises 2 claim 1 , 3 claim 1 , 4 claim 1 , 5 claim 1 , 6 claim 1 , 7 or 8 magnets arranged in a circular pattern where the magnets are arranged with circularly equal spacing.4. The dose detection system as in claim 1 , wherein the rotational position and/or a rotational movement of the magnet ring is determined using a DFT algorithm.6. The add-on device as in claim 5 , wherein the drug delivery device further comprises:drug expelling structure comprising a rotatable dose setting member allowing a user to set a dose amount of drug to be expelled,the add-on device being adapted to engage the dose setting member allowing a user to set a dose amount of drug to be expelled via the add-on device.7. The add-on device as in claim 5 , wherein the magnet ring comprises 2 claim 5 , 3 claim 5 , 4 claim 5 , 5 claim 5 , 6 claim 5 , 7 or 8 magnets arranged in a circular pattern where the ...

DOSE SETTING DEVICE FOR AN INJECTION DEVICE

A dosing device for an injection device, the dosing device including an actuating element for adjusting and/or dispensing a dose from the injection device, a thrust element for generating a forward movement for discharging a dose and a coupling to which the actuating element and the thrust element are coupled such that a rotational movement of the actuating element is transmitted directly to the thrust element and an axial movement of the actuating element is different than an axial movement of the thrust element. 1. An injection device comprising a dose setting device and an ampoule containing a substance , said dose setting device comprising:a housing;an operating element in threaded engagement with the housing and rotatable to move in a proximal direction for setting a dose;a driving element for generating a driving movement to dispense the dose, the driving element being in threaded engagement with the housing;wherein the threaded engagement of the operating element with the housing comprises a thread pitch different from a thread pitch of the threaded engagement of the driving element with the housing;a coupling by which the operating element and driving element can be coupled to dispense the dose set by the operating element so that a rotating dispensing movement of the operating element is transmitted directly to the driving element;a counter-rotation locking element coupled with the driving element, the locking element adapted to permit a rotation of the driving element in one direction and prevent a rotation of the driving element in the opposite direction;whereby during dispensing the dose the locking element rotates relative to the housing to produce dispensing clicking noises, wherein when the dose is being set or the dose is being corrected, the locking element generates no clicking noises.2. The injection device of claim 1 , wherein the locking element comprises a ratchet part having one or more elements or arms biased radially outwardly claim 1 , ...

Drug delivery system with multipolar magnet and sensor system

A drug delivery system comprises an indicator element and a sensor system. The indicator element is arranged to rotate relative to a reference component and corresponding to a reference axis and comprises a plurality of dipole magnets. The sensor system comprises a plurality of magnetometers arranged non-rotational relative to the reference component and adapted to determine continuous magnetic field values from the plurality of dipole magnets, as well as processor means configured to determine on the basis of measured values from the plurality of magnetometers a rotational position and/or a rotational movement of the indicator element.

PLUNGER SUB-ASSEMBLY FOR A PREFILLED MEDICAMENT INJECTOR, A PREFILLED MEDICAMENT INJECTOR AND METHOD FOR ASSEMBLING A PREFILLED MEDICAL INJECTOR

A plunger sub-assembly () for a pre-filled medicament injector for expelling a dose of a medicament, comprising: a) a container () holding a medicament, the container () comprising a body () with a proximally facing rim surface (), and a distally slideable piston (); b) a plunger (); and c) a tolerance compensating element () configured to cooperate with the plunger () and to cooperate with either the proximally facing rim surface () or the piston (), the tolerance compensating element () being rotatable relative to the plunger () to adjust the piston () end of dose position. The plunger sub-assembly () is formed so that end of dose state occurs by the plunger () cooperating with the proximally facing rim surface (). Pre-filled medicament injectors and methods of assembling a pre-filled medicament injector are further described. 2. A plunger sub-assembly as defined in claim 1 , wherein claim 1 , when the plunger assumes the end position claim 1 , a distally facing geometry of the plunger engages directly with the piston claim 1 , whereas the tolerance compensating element directly engages both the plunger and the proximally facing rim surface claim 1 , and wherein the tolerance compensating element is formed as a collar arranged circumferentially relative to the plunger and having a distal annular surface claim 1 , the distal annular surface configured for engaging the proximally facing rim surface.3. A plunger sub-assembly as defined in claim 1 , wherein one of the plunger and the tolerance compensating element comprises a contour system comprising a plurality of circumferentially disposed stop surfaces that are arranged axially offset relative to each other claim 1 , and wherein the other of the plunger and the tolerance compensating element comprises a counter stop surface arranged to axially engage a selective one of the plurality of circumferentially stop surfaces claim 1 , and wherein claim 1 , when in an initial assembly configuration claim 1 , the tolerance ...

Methods of treatment using a syringe extrusion accessory

A method of treatment may include providing a syringe having medicinal fluid therein for administering to a patient and coupling an attachment portion of an extrusion accessory having a handle and a pawl to a flange portion of the syringe. The pawl may have first and second ends, and be hingedly and rotatably coupled relative to the handle at a first position at the first end and at a second position between the first and second ends. The method may further include applying a force to translate the handle in a direction substantially perpendicular relative to a longitudinal axis of the syringe to cause axial movement of the second end of the pawl. The second end of the pawl may be engaged with a plunger of the syringe and axial movement of the second end of the pawl may drive the plunger forward to extrude the medicinal fluid from the syringe.

INJECTION APPARATUS COMPRISING A LATERALLY ATTACHED ACTUATION MEMBER FOR TRIGGERING THE PRODUCT RELEASE

A drive and metering apparatus for an injection apparatus for releasing a liquid product, the drive and metering apparatus comprising: a) a housing, b) a dose adjustment member, which is rotatable relative to the housing for adjusting the product dose to be released, c) an actuation member which is displaceable from a non-actuated position, which it assumes while adjusting the product dose to be released, into an actuated position, which it assumes while it releases the product, wherein the displacement of the actuation member into the actuated position triggers a product release and the actuation member comprises an actuation section, which is accessible to a user of the drive and metering apparatus and by means of which the user can displace the actuation member from the non-actuated position into the actuated position, d) wherein the actuation section is arranged distally in relation to the dose adjustment member. 1. A drive and metering apparatus for an injection apparatus for release of a liquid product , the drive and metering apparatus comprising:a) a housing;b) a dose setting member configured to rotate relative to the housing for setting the product dose to be released; andc) an actuation member configured to shift from an unactuated position, which it takes during the setting of the product dose to be released, to an actuated position, which it takes during product release, wherein shifting of the actuation member into the actuated position triggers the product release, and the actuation member comprises an actuation section to which a user of the drive and metering apparatus has access and by which the user can shift the actuation member from the unactuated position to the actuated position,characterized in that,d) the actuation section is disposed distal to the dose setting member.2. The drive and metering apparatus of claim 1 , wherein the drive and metering apparatus comprises a distal end and a proximal end claim 1 , and the actuation section is ...

DRUG INJECTION DEVICE WITH DEFLECTABLE TRANSDUCER

The present invention provides a drug injection device (″) comprising a first element () and a second element (″) configured to undergo movement relative to each other corresponding to an action performed on or by the drug injection device (″), wherein the first element () comprises serially disposed protrusions (), and wherein the second element (″) comprises a second element base and a deflectable transducer (″). The deflectable transducer (″) defines a base portion attached to the second element base, and a deflectable portion () configured for sequentially cooperating with the plurality of protrusions (), wherein a processor () is electrically connected with the deflectable transducer (″) to register activation signals. The deflectable transducer (″) comprises a carrier foil () that extends from the base portion to the tip end of the deflectable portion (), and a sensor element comprising a strain sensitive material () disposed on the carrier foil () and extending from the base portion towards the tip end of the deflectable portion (), wherein the carrier foil (), between the base portion and tip end of the deflectable portion (), comprises a non-supported portion having said strain sensitive material () disposed at least partly along the non-supported portion. 1. A drug injection device comprising:a first element and a second element configured to undergo relative movement in respect of each other, said movement corresponding to an action performed on or by the drug injection device and representing an amount of drug delivered or to be delivered from the drug injection device,wherein the first element comprises a plurality of protrusions serially disposed along a trajectory of said relative movement, the protrusions protruding in a protruding direction,wherein the second element comprises a second element base, and at least one deflectable transducer configured for sequentially cooperating with the plurality of protrusions of the first element to generate an ...

Optical dose measurements in syringes

Measurements of insulin quantities in a syringe are performed optically in an integrated insulin dose recorder/blood glucose meter. The syringe (80) is placed in a holder (320) before and after the administration of the dose. Liquid quantities in the syringe are determined by comparing optical response patterns of the syringe with calibration data stored in the device. Dose histories are downloaded to a patient computer for transfer to a clinician's computer. Standard or customized syringes (e.g., with marked plungers) may be used. Other wave energy carriers such as sound waves may also be used.

Medication injector apparatus with drive assembly that facilitates reset

A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen. The injection pen also may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.

Injection device with torsion spring and rotatable display

The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

Measured dose syringe

Administration instrument for medical use

An administration instrument for medical use performs injection of a drug solution with stability and with great reliability. The administration instrument includes a needle that does not wobble, thereby alleviating physical and mental pain of the administration patient. The structure includes an injection button that is pressed at an angle that is not parallel to the needle with respect to a direction in which the needle is inserted into the skin. Thus, it is possible to prevent the force of pressing the injection button from being transmitted in a direction of insertion of the needle so that the needle is inserted deeper into the skin than the initial insertion of the needle, thereby achieving administration under a stable state.

Accurate metering system

The present invention is directed to metering devices, systems, and methods that mitigate differential thermal expansion/contraction for the efficient, accurate, and reproducible metered delivery of fluids. The present invention allows the net fluid volume and a plunger location within a fluid dispensing container to automatically adjust under the influence of differential thermal expansion/contraction between the fluid and the fluid dispensing container that the fluid is contained within. Further, the present invention allows the metering system drive to sense the adjusted plunger location and allows the metering system drive to re-zero itself to produce an accurate volumetric delivery of fluid from the fluid dispensing container. The metering system includes means for controlling the travel of the metering system drive, and hence the travel of the plunger into the fluid dispensing container, for delivering accurate/precise amounts of the fluid from the fluid dispensing container. The metering system may also mitigate dead volume in the metering system.

Drive mechanism for a medication delivery device and medication delivery device

A drive mechanism for a medication delivery device containing a resilient member and having a rotation member configured to be rotated in a first direction during setting of a dose of a medication and to be rotated in a second direction during delivery of the dose, where rotation member is coupled to a drive member that is coupled to a piston rod such that on dose delivery the piston rod is displaced in a distal direction to dispense a medicament and where the resilient member prevents movement of the drive member and the piston rod during dose setting.

Resettable drive mechanism for a medication delivery device and medication delivery device

A resettable drive mechanism comprising a housing, a drive member rotatable in a second direction for delivering a dose of a medication, a piston rod driven by the drive member when it rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite to the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery position and a reset position. When the clutch member is in the delivery position, the stop member and the drive member are engaged and the drive member is prevented from rotating in the first direction, and when the clutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction and the piston rod is movable in the proximal direction.

Injektionspen

Pen-type injector with a microprocessor and blood characteristic monitor

A medical injection device, such as a pen-type injector has a microprocessor coupled to the injector that records the date, the time, and the amount of each injection. The microprocessor may also be coupled to a display to indicate the amount of medication to be injected. The medical injection device can also be coupled with a blood characteristic monitor to analyze characteristics of the blood. This provides a single, all-in-one device that performs a variety of functions, and requires only a minimum of space. The medical injection device may also use a disposable needle that substantially eliminates or reduces bleeding from an opening in the skin at the injection site.

SYRINGE WITH AN ELECTRONIC REPRESENTATION OF THE PARAMETERS.

SE PRESENTA UNA JERINGA QUE TIENE UN MECANISMO DE AJUSTE DE LA DOSIS, UN BOTON QUE PUEDE SER ACCIONADO PARA INYECTAR UNA DOSIS AJUSTADA, UN CONMUTADOR ACCIONADO EN UN MOMENTO DADO ENTRE EL INICIO Y LA FINALIZACION DE LA INYECCION Y UNA REPRESENTACION ELECTRONICA DE PARAMETROS TALES COMO LA MAGNITUD DE LA DOSIS AJUSTADA Y LA ULTIMA DOSIS INYECTADA, LA JERINGA TIENE ADEMAS UN RELOJ DE DETENCION QUE SE REINICIALIZA Y SE PONE EN MARCHA CUANDO SE ACCIONA EL CONMUTADOR. EL ESTADO DE LA FUNCION DEL RELOJ SE REPRESENTA ELECTRONICAMENTE Y JUNTO CON LOS PARAMETROS ELECTRONICOS REPRESENTADOS REPRODUCIDOS SOBRE UNA PANTALLA MUESTRA EL NUMERO DE HORAS QUE HAN PASADO DESDE EL ACCIONAMIENTO DEL CONMUTADOR CONMUTANDO SOBRE UN NUMERO CORRESPONDIENTE DE SEGMENTOS DE 30 DE UN CIRCULO. EL TAMAÑO DE LAS DOSIS SE REPRESENTA MEDIANTE NUMEROS ARABIGOS COMUNES. A SYRINGE IS PRESENTED THAT HAS A DOSE ADJUSTMENT MECHANISM, A BUTTON THAT CAN BE DRIVEN TO INJECT AN ADJUSTED DOSE, A SWITCH OPERATED AT A TIME GIVEN BETWEEN THE START AND END OF THE INJECTION AND AN ELECTRONIC REPRESENTATION AS A TOTAL PARAMETER THE MAGNITUDE OF THE ADJUSTED DOSE AND THE LAST INJECTED DOSE, THE SYRINGE ALSO HAS A DETENTION CLOCK THAT IS RESTARTED AND STARTED WHEN THE SWITCH IS OPERATED. THE STATUS OF THE CLOCK FUNCTION IS REPRESENTED ELECTRONICALLY AND TOGETHER WITH THE REPRESENTED ELECTRONIC PARAMETERS REPLACED ON A DISPLAY SHOWS THE NUMBER OF HOURS THAT HAVE PASSED SINCE THE SWITCH OPERATION SWITCHING ON A CORRESPONDING NUMBER OF A SEGMENT CIRCUIT. THE DOSE SIZE IS REPRESENTED BY COMMON ARABIGUM NUMBERS.

Medication delivery pen

A medication delivery pen includes a housing having an actuator disposed in the proximal end of the housing for setting and administering a dosage of medication, a medication-containing cartridge assembly having a cartridge with a pierceably sealed distal end, an open proximal end removably attachable to the distal end of the housing, and a piston in sliding, fluid tight engagement within the cartridge. A drive mechanism is coupled between the actuator and the cartridge to exert an axial force on the piston to inject the set dosage of medication. The actuator triggers the drive mechanism to administer the injection of medication held in the cartridge and a processor is coupled to the actuator to determine a value equal to the dosage set by the actuator. The drive mechanism includes a pair of half nuts in rotational engagement with the actuator, a non-rotatable lead screw having a distal end for exerting the axial force on the piston to inject the set dosage of medication, a proximal end, and threads extending between the proximal and distal ends. The nuts open and close radially to selectively engage with the threads of the lead screw for axially advancing along the lead screw upon rotation of the actuator.

Reusable medication delivery device

Electronic medical delivery pen having a multifunction actuator

A medication delivery pen includes a housing having opposing proximal and distal ends. An actuator is disposed in the proximal end of the housing for setting and administering a dosage of medication. The pen also includes a medication-containing cartridge assembly having a cartridge with a pierceably sealed distal end, an open proximal end removably attachable to the distal end of the housing, and a piston in sliding fluid tight engagement within the cartridge. A drive mechanism is coupled between the actuator and the cartridge to exert an axial force on the piston to inject the set dosage of medication. The actuator triggers the drive mechanism to administer the injection of medication held in the cartridge. A processor is coupled to the actuator to determine a value equal to the dosage set by the actuator. A memory device is coupled to the processor to store at least the dosage value determined by the processor. A display is located on the housing and coupled to the processor for displaying information provided by the processor. In a first state the actuator engages with the drive mechanism to deliver the medication and in a second state is disengaged from the drive mechanism. In its second state, the actuator serves as a user adjustable input for changing and setting mode parameters of at least one preselected mode of the pen.

Injector apparatus having a re-energising element

An injector apparatus comprises a housing (10 1 , 10 2 ) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance said plunger in respective predetermined increments of magnitude to express said successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to said plunger (40), and said dose setting arrangement comprises a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of said plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during said dose setting routine to inhibit forward movement of the plunger and/or to isolate said dose setting element from the force of said drive spring.

Dose setting device

A dose setting device for a delivery system has a piston rod ( 6, 9 ) which successively presses a piston ( 2 ) into a cylinder ampoule ( 1 ). Doses are set by rotating a second part ( 9 ) of the piston rod ( 6, 9 ) in relation to a first part ( 6 ). The two parts are connected by mating threads so that the total length of the piston rod ( 6, 9 ) is increased proportional to the angle of rotation, and a point ( 18 ) on the second part is moved away from a stop position fixed in relation to a housing ( 5 ) The set dose is delivered when the point ( 18 ) is moved back to the stop position. The first part ( 6 ) can be axially displaced but not rotated in the housing ( 5 ), and the second part ( 9 ) can both rotate and be axially displaced. The first part ( 6 ) is maintained in abutment with the piston ( 2 ) and the second part ( 9 ) is coupled to be rotated by a dose setting wheel ( 20 ). An injection push button ( 10 ) is movable between a projecting position and a pressed home position and has elements ( 13 ) acting on the second part ( 9 ) to press this part to its stop position.

A liquid medication delivery device and a method of reducing dripping

The invention relates to : A liquid medication delivery device (1) for delivering an intended dose, said delivery device including means (11) for holding a cartridge (12), a cartridge (12) for holding a liquid (16) to be fully or partially injected into a body, said cartridge (12) having an outlet (121) connected to a needle at one end (123) and a moveable wall (122) at another end (124), said movable wall (122) having an inner (1221) face and an outer (1222) face, and a piston rod (18) being operable to engage and displace said movable wall (122). The object of the present invention is to reduce the overall injection time, while improving the dose accuracy for a liquid medication delivery system. The problem is solved in that the piston rod is adapted to sequentially advance the outer face of said movable wall to return to a position corresponding to the intended dose. This has the advantage of improving the performance of the delivery device. The invention may e.g. be used in pen type or doser type injection devices or in pump type infusion devices for continuous delivery of medicaton in connection with the treatment of a disease such as diabetes.

Insulinpen

Die vorliegende Erfindung betrifft eine Insulinpen mit einer im vorderen Bereich angeordneten auswechselbaren Einspritznadel, einer dahinter angeordneten auswechselbaren Insulinpatrone sowie einer Pumpeinheit, deren verschiebbare Gewindestange auf einen im rückwärtigen Bereich der Insulinpatrone angeordneten Kolben einwirkt, ferner einem am rückwärtigen Ende dr Pumpeinheit angeordneten Drehknopf mit sowohl mechanisch als auch akustisch wahrnehmbaren Raststellungen, ferne einer digitalen LED-Anzeige mit visueller Darstellung der durch den Drehkopf eingestellten Insulinmenge sowie einem Startknopf, mit welchem der Einspritzvorgang unter die Haut des jeweiligen Patienten zur Auslösung gelangt. Um bei Diabetikern mit eingeschränkter bzw. nicht vorhandener Sehfähigkeit die Benutzung einer derartigen Insulinpen zu erleichtern, ist im Rahmen der vorliegenden Erfindung vorgesehen, daß innerhalb der Pumpeinheit (1) zusätzlich ein Sprachchip sowie ein Miniaturlautsprecher (14) vorgesehen sind, welche die durch den Drehknopf (10) eingestellte Menge von Insulineinheiten akustisch zur Wiedergabe bringen.

Drive mechanism for drug delivery device, and drug delivery device

FIELD: medicine. SUBSTANCE: invention refers to medical equipment, namely to drug delivery devices. The device comprises a drive mechanism and a cartridge with a number of drug doses. The drive mechanism comprises a body, a rotation element, a piston rod, a drive element and a shut-off element. The rotation element rotates in the first direction about the body when setting a dose, and in the second direction when delivering a dose. The piston rod moves in the distal direction in relation to the body for dose delivery. The drive element follows the rotation of the rotation element in the second direction when delivering a dose. The shut-off element prevents the rotation of the drive element about the body in the first direction when setting a dose. The rotation of the drive element converts into the rotation of the piston rod about the body. The rotation of the drive element in the second direction converts into the motion of the piston rod in the distal direction in relation to the body by a mechanical interaction of the drive element and the rotation element. EFFECT: invention provides the improved dosage accuracy and higher reliability. 16 cl, 18 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 515 867 C2 (51) МПК A61M 5/315 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2011128680/14, 09.12.2009 (24) Дата начала отсчета срока действия патента: 09.12.2009 Приоритет(ы): (30) Конвенционный приоритет: (43) Дата публикации заявки: 20.01.2013 Бюл. № 2 (73) Патентообладатель(и): САНОФИ-АВЕНТИС ДОЙЧЛАНД ГМБХ (DE) (56) Список документов, цитированных в отчете о поиске: US 5827232 A, 27.10.1998. WO 03080160 A1, 02.10.2003. RU 2214286 C2, 20.10.2003 . US 1718596 A, 25.06.1929. US 2653604 A, 29.03.1953. . . (86) Заявка PCT: EP 2009/066742 (09.12.2009) C 2 C 2 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 12.07.2011 (87) Публикация заявки PCT: 2 5 1 5 8 6 7 WO 2010/006796 (17.06.2010) R U 2 5 1 ...

Инъекционное устройство, снабженное электронными средствами определения дозы

Изобретение относится к медицинской технике, а именно к инъекционному устройству, имеющему механизм для установки дозы, использование которого обеспечивает запасание энергии в пружинном компоненте, т.е. к так называемому "устройству для автоинъекции". Инъекционное устройство для осуществления инъекции дозы медикамента содержит механизм для установки дозы, приводимый в действие для установки желательной дозы, механизм для осуществления инъекции, средство электронного детектирования объема установленной дозы и/или средство электронного детектирования объема инъецированной дозы, и электронное табло. Функционирование механизма для установки дозы обеспечивает запасание энергии в пружинном компоненте. Механизм для осуществления инъекции содержит шток поршня, выполненный с возможностью взаимодействия с поршнем, расположенным внутри картриджа, который содержит подлежащий инъецированию медикамент, и обеспечивающим выведение установленной дозы из картриджа через инъекционное устройство. Механизм для осуществления инъекции приводится в действие высвобождением энергии, запасенной в пружинном компоненте во время установки дозы. Электронное табло отображает для пользователя установленную дозу и/или инъецированную дозу. Средство электронного детектирования объема установленной дозы и/или средство электронного детектирования объема инъецированной дозы выполнены с возможностью детектирования перемещений подвижного компонента, который способен вращаться в двух противоположных направлениях и на который в одном из указанных направлений воздействует упругое усилие. Изобретение повышает точность до РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 453 343 (13) C2 (51) МПК A61M 5/20 (2006.01) A61M 5/315 (2006.01) G01D 5/24 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2009114321/14, 28.09.2007 (24) Дата начала отсчета срока действия патента: 28.09.2007 (72) Автор(ы): МЁЛЛЕР Клаус Шмидт (DK), КВОЛСБЬЕРГ Бо (DK) (73) ...

Device for injections furnished with torsional spring and rotary indicator

FIELD: medicine. SUBSTANCE: invention refers to medical equipment, in particular to device for injections, such as handle-injector with mechanism of windup where digital symbols displaying value of inserted from the device dose are shown within rotational angle, exceeding one complete turn. Device for injections contains unit setting dose liable for insertion from device for injections, torsional spring functionally connected with unit setting dose and detecting element. Detecting element is manufactured with capacity of rotational movement and adapted for displaying inserted from the device dose for injections in accordance with position of unit setting dose. Detecting element is set with capacity of rotational movement within rotational angle according to at least one complete turn. EFFECT: invention provides improved and more favorable for customer procedure of setting the dose by means of expanded scale of doses with high resolution. 13 cl, 5 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 388 498 (13) C2 (51) МПК A61M 5/315 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ, ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (30) Конвенционный приоритет: 21.10.2004 EP 04077899.5 (73) Патентообладатель(и): НОВО НОРДИСК А/С (DK) (43) Дата публикации заявки: 27.11.2008 2 3 8 8 4 9 8 (45) Опубликовано: 10.05.2010 Бюл. № 13 (56) Список документов, цитированных в отчете о поиске: ЕР 0338806 А2, 25.10.1989. US 6004297 А, 21.12.2001. RU 2212254 С2, 20.09.2003. RU 2091087 С1, 27.09.1997. US 2002/165500 A1, 07.11.2002. 2 3 8 8 4 9 8 R U (86) Заявка PCT: EP 2005/011287 (20.10.2005) C 2 C 2 (85) Дата перевода заявки PCT на национальную фазу: 21.05.2007 (87) Публикация PCT: WO 2006/045528 (04.05.2006) Адрес для переписки: 191186, Санкт-Петербург, а/я 230, "АРСПАТЕНТ", пат.пов. М.В.Хмаре, рег.№ 771 (54) УСТРОЙСТВО ДЛЯ ИНЪЕКЦИЙ, СНАБЖЕННОЕ ТОРСИОННОЙ ПРУЖИНОЙ И ПОВОРОТНЫМ ИНДИКАТОРОМ (57) Реферат: Изобретение относится к медицинской технике, а именно к ...

用于药物输送设备的驱动机构和药物输送设备

提出了一种用于药物输送设备(1)的驱动机构，所述驱动机构包括：具有近端和远端的壳体(13、17、40)；旋转构件(21)，所述旋转构件适配成在设定药物剂量(5)的过程中相对于所述壳体向第一方向转动而在输送剂量的过程中相对于所述壳体向第二方向转动，所述第二方向与所述第一方向相反；活塞杆(12)，所述活塞杆适配成相对于所述壳体向远端方向位移，用来输送剂量；驱动构件(20)，在所述剂量输送过程中，所述驱动构件适配成跟随所述旋转构件向所述第二方向的旋转运动；和止挡构件(26)，所述止挡构件适配成在设定剂量的过程中阻止所述驱动构件相对于所述壳体向所述第一方向旋转运动，其中所述驱动构件向第二方向的旋转运动转化成所述活塞杆相对于所述壳体向远端方向的运动。此外，还提供了一种药物输送设备。

An indication mechanism for an automatic applicator, particularly for insulin

본 발명은 특히 인슐린 또는 다른 액체 제제용, 특히 교체식 용기로부터의 약제의 설정된 투여량의 다중의 주입 투여용, 예를 들어, 당뇨병 환자에 의한 인슐린의 자가-적용을 위한 자동 어플리케이터를 위한 표시 기구에 관한 것이다. 서로 이동가능하게 커플링된 2개 이상의 배럴의 어셈블리를 포함하는 자동 어플리케이터를 위한 표시 기구는 구동 배럴(1) 상에 장착된 표시 배럴(2)이 그 외표면 상에 오직 마킹(2.1)만을 포함하며 풀-푸쉬 조절 너트(3)에 동축으로 연결됨을 특징으로 한다. The present invention relates to an indication device for automatic application of multiple doses of a defined dose of a medicament, in particular for insulin or other liquid preparations, in particular from a replaceable container, for example for the self-application of insulin by a diabetic patient . An indicator for an automatic applicator comprising an assembly of two or more barrels movably coupled to one another is characterized in that the indicator barrel (2) mounted on the drive barrel (1) comprises only markings And is coaxially connected to the full-push adjusting nut (3).

マイクロプロセッサおよび特性モニタを備える薬物投与装置

(57)【要約】 薬物投与装置、たとえば、ペン型注射器（１０）、ジェット注射器、薬物ポンプ、吸入器、噴霧器などは、各薬物投与の日付、時刻、および量を記録する前記装置に結合するマイクロプロセッサ（３２）を備える。また、マイクロプロセッサ（３２）は、表示器（３４）に結合され、投与される必要がある薬物の量を示す。薬物投与装置は、血液の特性を分析する血液特性モニタ（２０２）にも結合される。これによって、すべてを一体化した単一の装置が提供され、この装置は多様な機能を実行するが、最小の空間しか必要としない。薬物投与装置は、使い捨て注射針を使用することができるので、注射箇所の皮膚の開口からの出血が事実上削除または低減される。

剂量重置机构

本发明涉及一种用在药物递送装置中的剂量重置机构，其中剂量重置机构包括布置在壳体中的剂量设置构件(10)，其旋转时用于设置剂量，并且沿相反的方向旋转时用于重置剂量。驱动构件(38)连接至活塞杆(41)使得当所述驱动构件旋转时，所述活塞杆轴向地移动作用在容器上以排出药物。连接构件(26)布置在剂量设置构件和驱动构件之间。连接构件和驱动构件通过棘齿装置(34，44)互连，使得当剂量设置构件旋转时所述连接构件也能旋转，但是被棘齿装置锁定为不能沿相反的方向移动。剂量设置构件还包括相互作用地连接至所述棘齿装置的至少一个剂量重置构件(18)和至少一个支撑元件(17)，使得当剂量设置构件沿相反的方向转动时，连接构件和驱动构件之间的互连被释放。

Start-up drive mechanism for drug delivery device, and drug delivery device

FIELD: medicine. SUBSTANCE: invention refers to medical equipment, namely to drug delivery devices. The device comprises a start-up drive mechanism and a drug cartridge, with the cartridge detachably attached to a body. The drive mechanism comprises a body, a drive element, a piston rod, a shut-off element and a clamping element. The drive element rotates in a second direction about the body for drug dose delivery and is splined to the piston rod. The piston rod is driven in a distal direction about the body with the drive element while it rotates in the second direction. The shut-off element prevents a rotation movement of the drive element in a first direction opposite to the second direction as it is geared with the shut-off element. The clamping element moves with respect to the body between a delivery position and a start-up position; when the clamping element is in the delivery position, the shut-off element and the drive element are geared to prevent the rotation of the drive element in the first direction with respect to the body, and when the clamping element is in the start-up position, the drive element and the shut-off element are out-of-gear, the drive element can rotate in the first direction with respect to the body, and the piston rod can move in a proximal direction with respect to the body. EFFECT: invention provides higher reliability of the drive mechanism and more accurate dose delivery. 16 cl, 18 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 515 486 C2 (51) МПК A61M 5/315 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2011128683/14, 09.12.2009 (24) Дата начала отсчета срока действия патента: 09.12.2009 Приоритет(ы): (30) Конвенционный приоритет: (43) Дата публикации заявки: 20.01.2013 Бюл. № 2 (73) Патентообладатель(и): САНОФИ-АВЕНТИС ДОЙЧЛАНД ГМБХ (DE) (56) Список документов, цитированных в отчете о поиске: US 1718596 A, 25.06.1929. US 7195616 B2, 27.03.2007 . US 2653604 A, 29 ...

Indication mechanism for automatic applicator, particularly for insulin

FIELD: medicine.SUBSTANCE: invention refers to medical equipment, namely an indication mechanism for an automatic applicator, particularly for insulin or other liquid drugs, particularly for multiple injections of established doses of a drug from an interchangeable container, e.g. for an unassisted administration of insulin in diabetic patients. The indication mechanism comprises an applicator body and a unit of at least two sleeves movably connected to each other. An indicator sleeve is mounted on a drive sleeve directly in the applicator body. The indicator sleeve contains an indicator marking only on its outer surface. The indicator sleeve is only mounted to slide, axially and lengthwise by a key connection directly on the outer surface of the single drive sleeve without touching the inner surface of the applicator body. The indicator sleeve with its distal end is coaxially and directly connected to a separate pull-and-push control nut adjoining the above and rotatable by a threaded connection on the drive sleeve which is coaxially and lengthwise pulled or pushed by the pull-and-push control nut along the drive sleeve. The indicator sleeve only serves to indicate the established dose and is functionally separated from a dose establishing mechanism.EFFECT: invention enables accurate controlled establishing and indicating of the established dose of the drug preparation, maintaining the automatic injection of the drug preparation with no effort and drug loss, eg caused by a backflow generated by the dose establishing, particularly by minimising an internal friction force in the device; making the scale with relatively large symbols in any numbers and combinations and characters and indication figures, by removing any elements consuming the space on the indicator sleeve.11 cl, 5 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 520 159 C2 (51) МПК A61M 5/20 (2006.01) A61M 5/315 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ...

驱动组件、和弹簧在药物递送装置中的使用

提供了用于药物递送装置的可复位驱动组件。该组件可包括壳体(10A、10B、10C)、相对壳体可旋转且相对壳体可在近端起始位置和远端末端位置间移位的活塞杆(20)、在分配剂量时使活塞杆朝末端位置向远端移位的驱动构件(30)、及止挡构件(50)。驱动构件可操作以与活塞杆相互作用以形成可解锁的第一互锁部，第一互锁部可操作以阻挡活塞杆相对驱动构件的近端方向运动。止挡构件可操作以与活塞杆相互作用以形成可解锁的第二互锁部，第二互锁部可操作以阻挡活塞杆相对壳体沿近端方向的运动。当驱动组件处于驱动模式时，第一和第二互锁部被锁定使得第一互锁部和所述第二互锁部阻止活塞杆从末端位置向起始位置沿近端方向运动。为将驱动组件从驱动模式切换为复位方式，活塞杆可相对于驱动构件旋转以解锁第一互锁部，且止挡构件和活塞杆可相对彼此旋转以解锁第二互锁部。当驱动组件处于驱动模式时，第一和第二互锁部被解锁从而允许活塞杆向起始位置沿近端方向运动。此外，提供了药物递送装置和弹簧的使用。

监测装置

本发明涉及一种布置为可操作地连接至药剂输送装置(12)的监测装置(10)，所述药剂输送装置(12)包括手动操作的可移动剂量激活元件(20)，所述监测装置(10)包括电子电路(42)，所述电子电路(42)包括光学传感器(68)，其中所述光学传感器(68)相对于所述剂量激活元件(20)定位，从而从初始位置检测所述剂量激活元件(68)的手动操作；所述电子电路还包括振动传感器(70)，其中所述振动传感器(70)相对于所述药剂输送装置定位，从而在所述剂量激活元件(20)被操作时检测由药剂输送装置产生的特定振动谱，其中所述电子电路(42)包括计算元件，在所述剂量激活元件(20)被操作时，该计算元件能够将来自光学传感器(68)的信息与来自振动传感器(70)的信息相关联，以便在设定了正确的剂量时进行记录。

具有零位置调节特征的药物输送装置

制造笔药物输送装置的方法包括以下步骤：（i）提供药物输送装置，所述药物输送装置包括剂量指示器构件，所述剂量指示器构件适于在剂量设定和剂量驱出期间对应于旋转轴线相对于壳体移动，所述指示器构件具有与未设定剂量用量相对应的初始位置，（ii）将指示器构件布置在初始旋转位置中，以及（iii）将具有预定旋转偏移的成对的零标记分别提供在壳体上和指示器构件上。通过这种布置，通过在笔装置已经被组装之后将对应的且旋转配对的零标记提供在笔壳体和指示器构件上来解决找到指示器构件的正确的初始（零）旋转位置的问题，这允许通过图像捕获和后续图像分析来检测“真实”的初始位置。

An injection device with electronic detecting means

本发明涉及具有电子检测工具的注射装，特别是一种用来注射一定剂量药物如治疗糖尿病所用胰岛素的注射装置（1），在剂量配制阶段，能量被蓄积在注射装置（1）的一个弹簧构件（9，24）内。在对先前配制剂量进行注射时，蓄积的能量被释放出来并被用来驱动注射机构。注射装置（1）还包括有配制剂量数电子检测工具以及/或已注射剂量数电子检测工具。电子检测工具可储存并/或记录与注射装置（1）注射有关的数据。

Drive unit, plunger rod, device for medication delivery and spring application

FIELD: medicine.SUBSTANCE: invention relates to medical equipment, namely to a drive unit for a device for medication delivery, the device for medication delivery and to the application of a spring in the device for medication delivery. The drive unit for medication delivery, made with a possibility of returning into an initial position, contains a case, a plunger rod, a drive element, intended for the displacement of the plunger rod in the distal direction to the terminal position when a dose is supplied, and a stopper. The case has the proximal end and the distal end. The plunger rod is made with a possibility of rotation relative to the case and with a possibility of displacement in the axial direction relative to the case between the proximal initial position and the distal terminal position. The drive element is made with a possibility of being brought into action for being brought into interaction with the plunger rod in order to form the first blocking means, made with a possibility of unblocking. The first blocking means can be brought into action to block the movement of the plunger rod in the proximal direction relative to the drive element. The stopper is made with a possibility of being brought into action for its bringing into interaction with the plunger rod in order to form the second blocking means, made with a possibility of unblocking. The second blocking means can be brought into action to block the movement of the plunger rod in the proximal direction relative to the case. When the drive unit is in the drive mode, the first and the second blocking means are blocked in such a way that the first blocking means and the second blocking means prevent the movement of the plunger rod in the proximal direction from the terminal position into the initial position. To transfer the drive unit from the drive mode into the mode of return into the initial position the plunger rod can be turned relative to the drive element to unblock the first blocking means. ...

Dose setting device

피스톤로드(6, 9)가 피스톤(2)을 실린더앰풀(1) 속으로 계속하여 누르는 투약시스템용 1회 투여량세팅장치에 의해서, 1회 투여량이 피스톤로드의 제 1 부분(6)에 관하여 피스톤로드(6, 9)의 제 2 부분(9)을 회전함에 의해서 세팅되고, 각 부분이 나사가공부를 맞물림에 의해 연결되어서 피스톤로드(6, 9)의 전체 길이가 회전에 비례하여 증가되고, 피스톤로드의 제 2 부분 상의 한 포인트(18)가 하우징(5)에 관하여 고정된 정지위치로부터 이격되어 이동된다. 상기 포인트(18)가 정지위치로 되돌아올 때 세팅된 1회 투여량이 투약된다. 피스톤로드의 제 1 부분(6)은 하우징 속에서 회전되지는 않으나 축방향으로 변위되며, 그리고 피스톤로드의 제 2 부분(9)은 축방향으로 변위될 수 있을 뿐만 아니라 회전될 수도 있다. 피스톤로드의 제 1부분(6)은 피스톤과의 접합부에서 유지되고 피스톤로드의 제 2부분(9)은 1회 투여량세팅휠(20)에 의해서 회전되도록 커플링된다. 주사누름버튼은 돌출위치와 눌려진 홈위치 사이에서 움직일 수 있고 피스톤로드의 제 2부분(9)을 그것의 정지위치로 누르도록 피스톤로드의 제 2부분 상에 작용하는 구성요소(13)를 갖추고 있다. With a single dose setting device for a dosage system in which the piston rods 6, 9 continue to press the piston 2 into the cylinder ampoule 1, the single dose is in relation to the first part 6 of the piston rod. It is set by rotating the second part 9 of the piston rods 6, 9, and each part is connected by engaging the threaded part so that the overall length of the piston rods 6, 9 is increased in proportion to the rotation. One point 18 on the second part of the piston rod is moved away from the fixed stop position with respect to the housing 5. The single dose set when the point 18 returns to the stop position is administered. The first part 6 of the piston rod is not rotated in the housing but is axially displaced, and the second part 9 of the piston rod can be rotated as well as axially displaced. The first part 6 of the piston rod is held at the junction with the piston and the second part 9 of the piston rod is coupled to rotate by a single dose setting wheel 20. The scan pushbutton is provided with a component 13 which is movable between the protruding position and the pressed home position and acts on the second part of the piston rod to press the second part 9 of the piston rod to its stop position. .

Drive unit, plunger rod, device for medication delivery and spring application

FIELD: medicine. SUBSTANCE: group of inventions relates to medical equipment, namely to drive unit for device for medication delivery and to device for medication delivery. Drive unit for medication delivery contains case, plunger rod, drive element and rotary displacing element. Case has proximal end and distal end. rod is made with possibility of displacement in axial direction and with possibility of rotation with respect to case between first angular position and second angular position. Drive element is made with possibility of displacement relative to case between first angular position and second angular position. Drive element is made with possibility of displacement in axial direction. Rotary displacing element is made with possibility of bringing into action for transmission of elastic displacing effort to plunger rod. Drive unit is made with such configuration that in order to set a dose drive element can be displaced in proximal axial direction relative to case and plunger rod from initial position into position of dose setting; in the process of dose setting plunger rod rotates in first rotation direction and after rotation is first rotation direction it turns in second rotation direction relative to case and drive element; drive element interacts with plunger rod to convert travel of drive element in proximal axial direction relative to case into rotary motion/rotation of plunger rod in first rotation direction towards second angular position against elastic displacing effort; and rotary displacing element interacts with plunger rod in such a way that plunger rod rotates in second rotation direction towards first angular position relative to drive element and case under impact of elastic displacing effort. Device for medication delivery contains case, cartridge, with plunger being held inside cartridge, plunger rod, drive element and spring. Case has proximal end and distal end. Plunger Rod is intended for displacement of plunger in distal direction ...

Injection device with the clutch to travel forward for limiting plunger

本发明公开了一种注射设备，包括：用于药筒或注射管的壳体(10 1 ，10 2 )；用于在使用中与药筒或注射管协作以压出连续剂量的柱塞(40)；用于选择剂量体积的剂量设定装置(16，20)；和驱动机构(22，24)，该驱动机构能够被释放以使所述柱塞以相应预定量值的增量前进，从而压出所述连续剂量。驱动机构包括用以直接或间接使所述柱塞(40)运动的驱动弹簧(22)，而所述剂量设定装置包括剂量设定元件(16)，该剂量设定元件在剂量设定过程中可移动以对于给定剂量限定所述柱塞的运动增量的量值。驱动机构还包括离合器装置(56)，所述离合器装置能够在所述剂量设定过程中操作以限制柱塞的向前运动和/或将所述剂量设定元件与所述驱动弹簧的作用力隔离。

Administration instrument for medical use

【課題】 安全かつ高い信頼性でもって薬液の注射を行うことが可能な医療用投与器具を提供することを目的としている。即ち、投与者が投与時に行うエアー抜き操作時の投与液量、日付、時刻については、メモリに記録できないようにし、信頼性のある投与履歴が残せる医療用投与器具を提供することを目的とする。 【解決手段】 エアー抜き時はスイッチ１０９ａ，１０９ｂがオフのため、注射ボタン１０６が押され、スイッチ１１３が一度オンし再びオフしても、マイクロプロセッサ１２５はエアー抜きの際の空打ちと判断し、注射液量、日付、時刻の履歴をメモリ１２２に記録しない。 【選択図】 図１９

DEVICE FOR INJECTION

1. Устройство для инъекций, используемое совместно с картриджем или шприцем для выдачи множества доз содержимого картриджа или шприца, содержащее:корпус (10, 10) для картриджа или шприца;плунжер (40), при использовании устройства взаимодействующий с картриджем или шприцем для последовательного выведения доз;узел (16, 20) установки дозы, обеспечивающий выбор объема дозы;приводной механизм (22, 24), освобождаемый для последовательного выведения указанных доз путем осуществления дискретной подачи плунжера с предварительным заданием размера шагов указанной подачи,отличающееся тем, что приводной механизм содержит приводную пружину (22) для придания движения плунжеру (40) непосредственно или через другие детали, а узел установки дозы содержит компонент (16) для установки дозы, перемещаемый в процессе установки дозы для задания величины дискретной подачи плунжера, соответствующей задаваемой дозе, при этом приводной механизм дополнительно содержит муфту, выполненную с возможностью блокировать на стадии установки дозы перемещение плунжера вперед и/или изолировать компонент для установки дозы от усилия, создаваемого приводной пружиной.2. Устройство по п.1, отличающееся тем, что компонент (16) для установки дозы выполнен с возможностью поворота в процессе задания величины дискретной подачи плунжера.3. Устройство по п.2, отличающееся тем, что муфта (56) содержит элемент, выполненный с возможностью перемещения между не блокирующим и блокирующим положениями.4. Устройство по п.3, отличающееся тем, что элемент муфты (56) выполнен с возможностью осевого перемещения совместно с элементом для установки дозы, при этом осевое перемещение ком РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2012 117 980 (13) A (51) МПК A61M 5/20 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2012117980/14, 15.10.2010 (71) Заявитель(и): ОУЭН МАМФОРД ЛИМИТЕД (GB) Приоритет(ы): (30) Конвенционный приоритет: 16.10.2009 GB 0918145.4 23.10.2009 US 12/604,782 17.03. ...

Assembly for a drug delivery device and drug delivery device

一种用于输药装置（1）的组件，包括：外壳（5）、旋转构件（15）、驱动构件（16）和至少一个纠正构件（7）。旋转构件（15）适合于相对于外壳（5）在第一旋转方向上旋转以输送一个剂量的药物（11）。驱动构件（16）可耦合到旋转构件（15）以输送该剂量。在输送模式中，驱动构件（16）和旋转构件（15）耦合为使驱动构件（16）因旋转构件（15）和驱动构件（16）的机械交互作用而允许旋转构件（15）在第一旋转方向上的旋转运动。在纠正模式中，旋转构件（15）和驱动构件（16）退耦以使旋转构件（15）在第一旋转方向上相对于驱动构件（16）可旋转。为了从输送模式切换成纠正模式，纠正构件（7）相对于外壳（5）可运动，其中该组件构造为使纠正构件（7）相对于外壳（5）的运动转换成驱动构件（16）和旋转构件（15）之间的相对运动，以使驱动构件（16）和旋转构件（15）退耦。

Medication delivery pen with variable increment dose scale

A medication delivery pen is provided having a pen body assembly and a cartridge assembly that are threadedly engageable with one another. The pen body assembly includes a rotatable driver for driving a cartridge plunger preselected distances that are in accordance with a desired dose of medication to be delivered. The driver providing different preset rates of injection.

Recyclable medication dispensing device

A multi-use pen-shaped medication dispensing device (20) made of a plastic material that is recyclable after the contents of the medication cartridge (40) have been exhausted. The device (20) is made of a minimal number of parts, which include a housing (22), a dial assembly (34), a generally cylindrical button assembly (32) located within the proximal end (50) of the dial assembly (34), an internally threaded nut (36), and an externally threaded leadscrew (38). The device (20) is arranged so that the dial (34) must be rotated to the zero dose position prior to setting a dose. The device (20) includes a lockout mechanism (52) that prevents the dial (34) from being depressed during dosing. The device (20) further includes a mechanism (157) that limits the maximum dosage that can be dialed up and a mechanism (230, 234) that prevents the user from dialing up a dosage greater than that remaining in the cartridge (40).

Syringe with electronic display of parameters

투약량 설정 메카니즘, 설정된 투약량을 주입하기 위한 주사 행위를 수행하기 위한 작동 버튼, 주사의 시작시 또는 완료시, 또는 주사의 시작과 완료사이의 한 시점에서 주사가 이루어질 때 작동되는 스위치 및 설정 투약량과 최종의 주사 투약량과 같은 관련 파라미터의 전자 표시 기능을 가진 유형의 주사기에 있어서, 스위치가 작동할 때, 리셋되어 시작되는 스톱워치를 더 포함하고 있으며, 스톱워치 기능 상태는 전자적으로 표시된다. 시계 기능의 상태는 전자적으로 표시되며 스위치의 작동이후에 경과하는 시간 수치를 원의 상응하는 수의 30도 세그먼트를 켬으로써 나타내는 디스플레이에서 재현되는 파라미터들과 함께 전자표시된다. 투약량 크기는 보통의 아라비아 숫자로 나타난다. An actuation button for performing a scanning act to inject a defined dose, a switch and a set dose to be actuated when the scan is performed at the beginning or completion of the scan, or at a point between the start and completion of the scan, A syringe of the type having an electronic display function of an associated parameter, such as an injection dose of the stopwatch function, wherein the stopwatch function status is displayed electronically when the switch is activated. The status of the clock function is displayed electronically and is displayed electronically with the parameters being reproduced in the display, which indicate the elapsed time value after the operation of the switch by turning on the corresponding number of the 30 degree segments of the circle. Dosage size is indicated by a normal Arabic number.

Measured dose dispensing device

Medication delivery pen cap actuated dose delivery clutch

A medication delivery pen is provided having a medication cartridge assembly, a pen body assembly and a cap. The pen body assembly includes a dose setting mechanism and a dose delivery mechanism that are selectively disconnected and connected by attaching and removing, respectively, the cap of the medication delivery pen. When the cap is attached to the medication delivery pen the user can easily dial in and correct the dialed in dosage and when the cap is removed the medication delivery pen is ready to dispense the dialed in dosage.

Vial injector device

An automatic medicament delivery device and corresponding method for use with a standard needle assembly and a standard vial container that contains a medicament is disclosed. A user attaches the needle assembly and the vial container to the device. The user can transfer and measure a dose from the vial container into the device. When the user presses the tip of the device against the injection site, a needle of the needle assembly is automatically injected into the user and the measured dose is delivered into the user through the needle. When the user removes the device from the injection site, the device is re-cocked for the next injection.

Durable needle-less jet injector apparatus and method

A gas-powered, durable, needle-less hypodermic jet injection device ( 10, 110 ) includes a hand-held injector ( 12, 112 ) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge ( 28 ) which is opened in preparation to effecting a jet injection, and which powers the jet injection, but from which pressurized gas is not allowed to flow in volume until a user of the device shifts a valving spool ( 24 ).

Method and device to inject medicine

일 실시예에 따른 약물 주입 장치는, 약물을 저장하는 약물 저장부; 상기 약물 저장부의 일측에 대해 외력(external force)을 가하도록 구성되는 가압부(press portion); 니들부 및 상기 약물 주입 장치가 결합될 시 상기 니들부와 연결되고, 상기 외력에 기초하여 상기 약물 저장부의 다른 일측으로부터 약물을 흡입하여 상기 니들부로 상기 약물을 토출하는 토출부(discharge portion); 및 주입량을 결정하고, 상기 결정된 주입량을 주입하도록 상기 토출부를 제어하는 제어부(control portion)를 포함할 수 있다. A drug injection device according to an embodiment includes: a drug storage unit for storing a drug; A press portion configured to apply an external force to one side of the drug storage unit; A discharge portion connected to the needle portion when the needle portion and the drug injection device are coupled, and discharges the drug to the needle portion by inhaling a drug from the other side of the drug storage portion based on the external force; And a control portion that determines an injection amount and controls the discharge unit to inject the determined injection amount.