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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 2832. Отображено 100.
26-01-2012 дата публикации

High Powered Light Emitting Diode Photobiology Device

Номер: US20120022618A1
Автор: Frances A. Beckman, Myk Wayne Lum
Принадлежит: Individual

A high-powered light emitting diode (LED) photobiology (phototherapy) device is disclosed in the accompanying specification. The contemplated photobiology (phototherapy) device may be used in the treatment of various aesthetic and medical or other conditions. The phototherapy device may include a number of select LEDs for emitting a desired range or ranges of wavelengths of high intensity light for use in treatment. Additionally, the phototherapy treatment includes one or more methods for providing a treatment appropriate to the condition desired to be treated. The phototherapy device provides for a variety of high power light settings, intensity levels, and selectable time intervals for providing treatment.

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Номер записи: 1
06-09-2012 дата публикации

Ingestible capsule for treating gastric infections, in particular for treating h. pylori infections

Номер: US20120226335A1
Автор: Barbara Orsini, Calogero Surrenti, Elisabetta Surrenti, Franco Fusi, Giovanni Romano, Monica Monici
Принадлежит: UNIVERSITA DEGLI STUDI DI FIRENZE

The light capsule object of the present invention is an ingestible device designed to illuminate the gastric cavity of the stomach for therapeutic purposes directed against Helicobacter pylori (H. pylori) bacteria. It comprises: a casing transparent to visible light, in turn containing punctiform light sources, preferably constituted by LEDs, positioned immediately under said casing and capable of emitting light at appropriate wavelength bands (preferably 405 nm and 630 nm); a battery, adapted to power the LED sources for approximately 20-30 minutes (the average transit time in the stomach); a switch which allows a delayed power on and allows the tablet to be still “off” when it is swallowed. The light emitted by the capsule strikes the H. pylori bacteria anchored on the gastric wall. The light radiation is preferentially absorbed by molecules of porphyrin produced by the bacterium which works as photosensitizing agent by inducing the formation of cytotoxic molecular species.

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Номер записи: 2
11-10-2012 дата публикации

Oral care compositions for use with an oral light device

Номер: US20120258053A1
Автор: Madhusudan Patel, Mahmoud Hassan, Rosa Paredes, Thomas Boyd
Принадлежит: Colgate Palmolive Co

Generally regarded as safe (GRAS) dyes can be used as photosensitizing dyes in oral compositions to provide anti-bacterial and anti-inflammatory efficacy. Embodiments include oral care compositions including photosensitizing dyes, methods of making the compositions, methods of using the compositions, and kits containing the compositions and light emitting devices.

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Номер записи: 3
02-05-2013 дата публикации

METHOD FOR PRODUCING SEVERAL INJECTION-MOLDED PARTS

Номер: US20130110030A1
Автор: DANIEL Dorit, HIRSZOWICZ Eran, HOLZER Asher
Принадлежит: Theracoat Ltd.

Apparatus and methods for treatment of an internal cavity are provided. The internal cavity is coated with a treatment solution. The treatment solution can include a solidifiable matrix with or without a drug or combination of drugs incorporated therein, or a drug solution without a solidifiable matrix. The treatment solution is coated onto at least a portion of the internal cavity, and acts as a slow-release drug delivery system. 1100-. (canceled)101. A method for preventing cell migration and adherence within an internal cavity during tumor resection so as to substantially prevent new cancerous growth , comprising steps of: i. a hydrogel-based biocompatible elastic adhesion substance comprising an agent adapted to increase adherence of a treatment solution to an internal wall of said internal cavity, said hydrogel-based biocompatible elastic adhesion substance adapted to conform to anatomical morphology of said internal wall;', 'ii. at least one treatment solution comprising at least one drug carrier polymeric material selected from the group consisting of polvinylpyrrolidone (PVP) with water as a solvent, polyethylene glycol (PEG) with water as a solvent, and any combination thereof; and a cancer-fighting drug;', 'iii. a buffering polymer for controlling concentration of said cancer-fighting drug reaching said internal wall of said internal cavity, said buffering polymer selected from the group consisting of polyurethanes, polyethylene terephthalate, polyactones, polycaprolactone, polyacrylonitrile, polyethylene glycol and any combination thereof; and,', 'iv. a blocking polymer for controlling the concentration of said cancer-fighting drug reaching said inner volume of said internal cavity; said blocking polymer selected from the group consisting of polyvinylchloride, polyurethanes, polyanhydride, polyethylene glycol and any combination thereof;, 'a. forming a drug carrier by incorporating into a hydrogel based biocompatible matrix each of the following ...

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Номер записи: 4
16-05-2013 дата публикации

Electric toothbrush, toothbrush bristle assembly, and method for manufacturing the toothbrush bristle assembly

Номер: US20130117950A1
Автор: Young Ha Kim
Принадлежит: Individual

One aspect of the present invention relates to an electric toothbrush in which an LED unit is mounted to perform oral sterilization and tooth whitening treatment during the brushing of the teeth, and further relates to a toothbrush bristle assembly for the electric toothbrush. The electric toothbrush according to one embodiment of the present invention comprises: a toothbrush bristle assembly including a handle having a vibrator, and a coupling space into which the vibrator is coupled. The toothbrush bristle assembly comprises: a toothbrush bristle body having a brush; an LED unit mounted on the toothbrush bristle body to perform oral sterilization and tooth whitening treatment; and a connector module having a first connector arranged in the toothbrush bristle body to interconnect the LED unit and a driving power source, as well as a second connector arranged in the vibrator.

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Номер записи: 5
06-06-2013 дата публикации

Periodontal treatment system and method

Номер: US20130143180A1
Автор: Douglas L. Glover, Enrico E. DiVito, Kemmons A. Tubbs, Mark P. Colonna, Robert E. Barr
Принадлежит: Medical Dental Advanced Tech Group LLC

Methods and apparatuses for treating a root canal in a tooth or hard and/or soft tissue within a tooth and surrounding tissues by pulsing a laser light into a reservoir, preferably after introducing liquid fluid into the reservoir, so as to disintegrate, separate, or otherwise neutralize pulp, plaque, calculus, and/or bacteria within and adjacent the fluid reservoir without elevating the temperature of any of the dentin, tooth, bones, gums, other soft tissues, other hard tissues, and any other adjacent tissue more than about 5° C.

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Номер записи: 6
20-06-2013 дата публикации

Devices and Methods for the Treatment of Endometriosis

Номер: US20130158347A1
Автор: GRILLO Francis P., McIntyre Jon T., Ostrovsky Isaac
Принадлежит: BOSTON SCIENTIFIC SCIMED, INC.

A tissue treatment device comprises an insertion section sized and shaped for insertion into the body via a trocar and a diagnostic element coupled to the insertion section, the diagnostic element illuminating tissue with light of a wavelength selected to facilitate identification of target tissue in combination with an ultrasound element coupled to the insertion section for delivering to a portion of tissue illuminated by the diagnostic element ultrasound energy. 120.-. (canceled)21. A tissue treatment device , comprising:an insertion section sized and shaped for insertion into a body;a diagnostic element coupled to the insertion section, the diagnostic element configured to illuminate a target area with a first light of a first wavelength and a second light of a second wavelength selected to facilitate identification of a select portion of a target tissue; andan ultrasound element coupled to the insertion section, the ultrasound element including a generating component that generates ultrasound energy for delivery to the select portion of the target tissue,wherein the diagnostic element and the ultrasound element are positioned and oriented within the insertion section such that the second light from the diagnostic element and the ultrasound energy from the generating component converge on a target spot.22. The device according to claim 21 , further comprising a control unit coupled to the diagnostic element and the ultrasound element claim 21 , the control unit remaining outside the body while the insertion section is inserted into the body.23. The device according to claim 22 , wherein the ultrasound element is coupled to an ultrasound controller located in the control unit.24. The device according to claim 23 , wherein the diagnostic element comprises a first illuminating component configured to generate the first light and a second illuminating component configured to generate the second light.25. The device according to claim 24 , wherein the first and second ...

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Номер записи: 7
20-06-2013 дата публикации

METHODS FOR THERMALLY-INDUCED RENAL NEUROMODULATION

Номер: US20130158442A1
Автор: Clark Benjamin J., Demarais Denise, Gelfand Mark, Levin Howard R., Thai Erik, Zadno Nicolas
Принадлежит: Ardian, Inc.

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. 1. A method of treating a human patient diagnosed with a cardio-renal disease or disorder , the method comprising:intravascularly delivering a device to a vicinity of a neural fiber associated with renal function of the patient; andthermally inhibiting neural communication along the neural fiber with the device.2. The method of wherein thermally inhibiting neural communication along the neural fiber with the device comprises thermally inhibiting afferent neural communication along the neural fiber with the device.3. The method of wherein thermally inhibiting neural communication along the neural fiber with the device comprises thermally inhibiting efferent neural communication along the neural fiber with the device.4. The method of wherein intravascularly delivering a device to a vicinity of a neural fiber associated with renal function comprises intravascularly delivering the device via a renal blood vessel to a position proximate to the neural fiber.5. The method of wherein intravascularly delivering the device via a blood vessel to a position proximate to the neural fiber comprises intravascularly positioning the device in contact with a wall of the blood vessel proximate to the neural fiber.6. The method of wherein thermally inhibiting neural communication along the neural fiber with the device ...

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Номер записи: 8
01-08-2013 дата публикации

METHOD AND APPARATUS FOR TOOTH REGULATION WITH HEAVY FORCES

Номер: US20130196284A1
Автор: Brawn Peter Robert
Принадлежит:

Methods are provided for regulating tooth movement and for maintaining or improving tissue health using heavy forces. Such methods comprise allowing a heavy force to be exerted on one or more teeth of a patient in need thereof; and administering an effective amount of light to the maxillary or mandibular alveolar bone of the patient, wherein the light is administered before, during, or after the heavy force is exerted. The light can have a wavelength in the range of about 585 nm to about 665 nm, or about 815 nm to about 895 nm. An apparatus useful for providing light therapy is also provided. 1. A method for regulating tooth movement , comprising:(a) allowing a heavy force to be exerted on one or more teeth of a patient in need thereof; and(b) administering an effective amount of light to the maxillary or mandibular alveolar bone of the patient, wherein the light is administered before, during, or after the heavy force is exerted.2. The method of claim 1 , wherein the heavy force has a magnitude ranging from about 175 grams of force to about 500 grams of force.3. The method of claim 1 , wherein the patient has an orthodontic appliance on one or more of the patient's teeth.4. The method of claim 3 , wherein the orthodontic appliance exerts the heavy force to the one or more teeth.5. The method of claim 1 , wherein the light is extra-orally administered to the maxillary or mandibular alveolar bone.6. The method of claim 1 , wherein the light is intra-orally administered to the maxillary or mandibular bone.7. The method of claim 1 , wherein the light has a wavelength of from about 585 nm to about 665 nm or from about 815 nm to about 895 nm.8. The method of claim 1 , further comprising installing an orthodontic appliance on one or more of the patient's teeth.9. The method of claim 8 , wherein installing the orthodontic appliance occurs prior to administering the light.10. The method of claim 8 , wherein installing the orthodontic appliance occurs subsequent to ...

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Номер записи: 9
05-09-2013 дата публикации

Light-emitting oral care implement

Номер: US20130227803A1
Автор: Bruce M. Russell, James H. Kemp
Принадлежит: Colgate Palmolive Co

An oral care implement comprises a head with a plurality of cleaning elements, and a light source incorporated into or adjacent the head. The light source is incorporated prior to the attachment of the cleaning elements for ease of manufacturing and a cost-effective assembly. The cleaning elements are preferably pre-formed and attached to the head after the incorporation of the light source so that the provision of the light source does not require any post-processing that might impair the integrity of the head or cleaning elements.

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Номер записи: 10
26-09-2013 дата публикации

Fluid management catheter and methods of using same

Номер: US20130253266A1
Автор: Alan J. Dextradeur, Daniel McCusker
Принадлежит: Codman and Shurtleff Inc

A catheter and method for managing fluid in a patient, the catheter having an elongated shaft with a distal end and a proximal end. The shaft defines at least one lumen extending substantially therethrough, the shaft further defining a plurality of drainage holes along a distal portion of the shaft, with the drainage holes in fluid communication with the lumen. The catheter further has a substantially transparent tip portion attached to the distal end of the shaft with an outer distal leading surface that is substantially rounded to assist insertion through tissue.

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Номер записи: 11
17-10-2013 дата публикации

ENDOSCOPES ENHANCED WITH PATHOGENIC TREATMENT

Номер: US20130274549A1
Автор: Muller David, Natale Anthony
Принадлежит:

Various endoscopes are integrated with an applicator configured for delivering a therapeutic solution to an internal anatomic target that may be infected by pathogenic microorganisms and a UV light-emitting device transmitting UV light thereto. 1. A system for examining an internal anatomical target in a patient's body and treating pathogenic infections therein , the system comprising:an endoscope for examining the internal anatomical target;a device for delivering actinic radiation, the radiation-delivery device having an emission channel; andan applicator comprising a reservoir for a radiation-activatable biocidal fluid and a fluidic channel,wherein a light output of the emission channel and a fluidic outlet of the fluidic channel are configured for accessing the internal anatomical target and delivering actinic radiation and a radiation-activatable biocidal fluid, respectively, thereto without interfering with operation of the endoscope.2. The system of claim 1 , wherein the endoscope claim 1 , device and the applicator are integrated into a single assembly.3. The system of claim 1 , wherein the endoscope is configured to enter a first surgical port and the light output and the fluidic outlet are configured to enter a second surgical port spaced apart from the first surgical port.4. The system of claim 1 , wherein the endoscope is a gastrointestinal endoscope claim 1 , comprising at least one working channel and at least one optical channel for guiding light to the internal anatomical target.5. The system of claim 4 , wherein the working channel is the fluidic channel and the optical channel is the emission channel.6. The system of claim 4 , wherein the emission channel and the fluidic channel are disposed within the working channel of the gastrointestinal endoscope.7. The system of claim 1 , wherein the endoscope is a cystoscope claim 1 , comprising a first channel for providing images of the internal anatomical target and a second channel for allowing fluids to ...

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Номер записи: 12
24-10-2013 дата публикации

Intra-oral light therapy apparatuses and methods for their use

Номер: US20130280671A1
Автор: Kevin Strange, Paul Mathews, Peter Brawn, Ryan BREDIN, Timothy G. SHAUGHNESSY
Принадлежит: BIOLUX RESEARCH Ltd

In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

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Номер записи: 13
24-10-2013 дата публикации

LIGHT IRRADIATION DEVICE, AND LIGHT IRRADIATION TREATMENT AND PREVENTION DEVICE PROVIDED THEREWITH

Номер: US20130282082A1
Автор: Daijo Kazuhiro, Shigehara Kazuto, Tsujikawa Nobuto
Принадлежит: Panasonic Corporation

A light irradiation device of the present invention includes: a light source that emits radiant light to an irradiation object; a reflecting member that reflects the radiant light emitted from the light source toward the irradiation object; and an irradiation member that includes at least two irradiation surfaces for transmitting the radiant light reflected from the reflecting member and irradiating the irradiation object with the radiant light. The light source emits the radiant light from one end side of the irradiation surfaces of the irradiation member, and the reflecting member includes: a first reflecting area that reflects the radiant light emitted from the light source toward a first irradiation surface of the irradiation member; a second reflecting area that reflects the radiant light emitted from the light source and indirectly reaches the second reflecting area, toward a second irradiation surface of the irradiation member; and a third reflecting area that guides the radiant light to the second reflecting area. Therefore, the light irradiation device and a light irradiation treatment and prevention device, which can irradiate a plurality of irradiation surfaces with the radiant light using one light source, can be configured. 1. A light irradiation device comprising:a light source that emits radiant light to an irradiation object;a reflecting member that reflects the radiant light emitted from the light source toward the irradiation object; andan irradiation member that includes at least two irradiation surfaces for transmitting the radiant light reflected from the reflecting member and irradiating the irradiation object with the radiant light,wherein the light source emits the radiant light from one end side of the irradiation surfaces of the irradiation member, and a first reflecting area that reflects the radiant light emitted from the light source toward a first irradiation surface of the irradiation member;', 'a second reflecting area that reflects ...

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Номер записи: 14
30-01-2014 дата публикации

TWO-WAY PHOTODYNAMIC THERAPY STEREO COLPOSCOPE FOR DIAGNOSING AND TREATING DISEASES OF THE FEMALE GENITAL TRACT

Номер: US20140031702A1
Автор: Diaz Sanchez Joel Gerardo, Zertuche Zuani Jose Gerardo
Принадлежит:

A stereo colposcope having variable linearity filter systems for both the excitation step and the suppression step, and can be used universally with any fluorescent compound or drug, as is the case of photodynamic diagnosis (PDD). The colposcope is a two-way colposcope because the treatment can be administered by an optical system or by a light-producing radio-frequency electrical current with a diathermic effect which facilitates photodynamic treatment. The colposcope produces ozone, which has an antiseptic effect when applied to the genital tract. A monitor provides for three-dimensional viewing through the use of two video cameras with the DLP (Digital Light Processing) and HDTV (High Definition Television) systems with the use of active lenses. 1. A two way photodynamic therapy stereocolposcope for diagnosis and treatment of female genital tract diseases , comprising:a lighting system in the head having a variable linear type excitation filter system, two suppressors or barrier filters being placed on said head, one for each observation optical axis; two diaphragms have been placed on the head, one on each optical axis with a manual opening controller.2. The two way photodynamic therapy stereocolposcope for diagnosis and treatment of female genital tract diseases according to claim 1 , further comprising a lighting system in the head having a variable linear type excitation filter system capable of selecting any light frequency range to send a light beam to any fluorescent compound placed in the female genital tract claim 1 , the compounds including one of fluorophores claim 1 , fluorescent proteins of any color for in vivo use claim 1 , or chemical dyes for fluorescence.3. The two way photodynamic therapy stereocolposcope for diagnosis and treatment of female genital tract diseases according to claim 1 , further comprising two variable linearity barrier or suppressor filters in the head claim 1 , one for each observation optical axis to analyze the frequency ...

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Номер записи: 15
06-02-2014 дата публикации

SYSTEM AND METHOD FOR DIAGNOSING AND TREATING DISEASE

Номер: US20140039323A1
Автор: SPECTOR DONALD
Принадлежит:

A method and system for diagnosing and treating infection or disease, in which an individual takes a photograph of an infected or diseased area of a body using a camera connected to a microprocessor. The photograph is sent to a diagnosing center having a server with a second microprocessor and a database of photographs correlated with different diseases and infections. The second microprocessor scans the image received from the camera and compares it to the photographs in the database. If a match is found, the second microprocessor then notes the disease or bacteria corresponding to the matching photograph. The second microprocessor then searches an additional database correslated to the match, to further refine the diagnosis. The second microprocessor then searches the second database for a treatment corresponding to the identified disease or bacteria. Once a treatment is identified, information regarding this treatment is automatically sent to the individual's microprocessor. 1. A method for diagnosing and treating infection or disease , comprising:inserting an endoscope into a patient's body, the endoscope having a light source and an extension on a distal end thereof;placing the extension underneath a layer of tissue in the patient;taking a photograph of said layer of tissue using a camera connected to a first microprocessor, the camera being connected to an endoscope;sending the photograph via the first microprocessor to a a server with a second microprocessor and a first database of photographs correlated with different diseases and infections, the photographs showing individual diseased cells or bacteria;enlarging and enhancing the photograph sent to the server via software so that individual cells or bacteria can be seen in the enhanced photograph;comparing the enhanced photograph with the photographs in the first database to identify the disease or infection, the step of comparing being undertaken by the second microprocessor using visual comparison ...

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Номер записи: 16
06-03-2014 дата публикации

Light emitting device with ceramic conversion material

Номер: US20140062336A1
Автор: Bernd Hofmann, Hans-Helmut Bechtel
Принадлежит: Koninklijke Philips NV

The invention relates to a light delivery device comprising a conversion element and one or several LEDs, which emit light into the conversion element. The light is then converted and emitted with a high radiant flux.

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Номер записи: 17
06-03-2014 дата публикации

LIGHT GUIDE TYPE PAIN RELIEVER

Номер: US20140065570A1
Автор: Chen Roger, Tsai Ming-Chih
Принадлежит:

A light guide type pain reliever includes a handle including a barrel accommodating a battery, a rear end cap and a front end cap respectively capped on two opposite ends of the barrel, a pushbutton mounted in the rear end cap and a switching connector mounted in the rear end cap and electrically connected to the battery and drivable by the pushbutton to switching on/off the battery, a holder shell connected to the front end cap and electrically coupled to the battery and having electrically connected thereto a vibrator and a light-emitting device, an adapter connected to the holder shell, and a light guide plate connected to adapter guiding out light rays emitted by the light-emitting device. 1. A light guide type pain reliever , comprising:a hollow handle, said hollow handle comprising a barrel accommodating therein a battery, a rear end cap capped on one end of said barrel, a pushbutton mounted in said rear end cap, a front end cap thread-connected to an opposite end of said barrel, and a switching connector mounted in said rear end cap and electrically connected to said battery, said switching connector comprising a switching rod linked to said pushbutton and drivable by said pushbutton to switch on/off said battery;a holder shell being a hollow member connected to said front end cap and electrically coupled to said battery, said holder shell having electrically connected thereto a vibrator and a light-emitting device;an adapter connected to said holder shell and adapted to accommodate said vibrator and said light-emitting device, said adapter comprising a plug hole located in a front side thereof; anda light guide plate having one end thereof plugged into said plug hole of said adapter and kept in line with said light-emitting device for receiving light rays emitted by said light-emitting device and an opposite end thereof suspending outside said adapter and provided with an insertion slot.2. The light guide type pain reliever as claimed in claim 1 , wherein ...

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Номер записи: 18
13-03-2014 дата публикации

Intra-oral light therapy apparatuses and methods for their use

Номер: US20140072932A1
Автор: Kevin Strange, Paul Mathews, Peter Brawn, Ryan BREDIN, Timothy G. SHAUGHNESSY
Принадлежит: BIOLUX RESEARCH Ltd

In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

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Номер записи: 19
27-03-2014 дата публикации

PERIODONTAL TREATMENT SYSTEM AND METHOD

Номер: US20140087333A1
Автор: Barr Robert E., Colonna Mark P., DiVito Enrico E., Glover Douglas L., Tubbs Kemmons A.
Принадлежит: Medical Dental Advanced Technologies Group LLC

Methods and apparatuses for treating a root canal in a tooth or hard and/or soft tissue within a tooth and surrounding tissues by pulsing a laser light into a reservoir, preferably after introducing liquid fluid into the reservoir, so as to disintegrate, separate, or otherwise neutralize pulp, plaque, calculus, and/or bacteria within and adjacent the fluid reservoir without elevating the temperature of any of the dentin, tooth, bones, gums, other soft tissues, other hard tissues, and any other adjacent tissue more than about 5° C. 1. A method for treating a treatment zone including one or more teeth and tissue adjacent such tooth or teeth , the combination thereof defining a treatment pocket there between , the method comprising the steps of:A. providing a laser system containing a source of a laser light beam and an elongate optical fiber connected to said source and configured to transmit said laser light beam to a tip thereof,B. immersing at least a portion of the tip into a fluid reservoir located in the treatment pocket, the fluid reservoir holding a first fluid;C. pulsing the laser light source at a first setting such that at least a substantial portion of any contaminants located in or adjacent the treatment pocket are destroyed or otherwise disintegrated into fragmented material in admixture in and with the first fluid, thereby forming a first fluid mixture, wherein the destruction or disintegration of a substantial portion of any contaminants located in or adjacent the treatment pocket using the laser light source is accomplished without generation of significant heat in the first fluid or associated mixture so as to avoid elevating the temperature of any gum, tooth, or other adjacent tissue more than about 5° C.2. The method of wherein the first setting of step (C) comprises an energy level of from about 2.0 W to about 4.0 W claim 1 , a pulse width of from about 50)..to about 300).. claim 1 , and a pulse frequency of from about 2 Hz to about 50 Hz.3. The ...

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Номер записи: 20
27-03-2014 дата публикации

METHODS AND DEVICES TO TREAT NASAL AIRWAYS

Номер: US20140088463A1
Автор: Frazier Andrew, Wolf Scott J.
Принадлежит: AERIN MEDICAL, INC.

A method is described for modifying at least one property of a tissue of or near a nasal valve of a nose, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in a nasal airway. The method may involve contacting a treatment element of a treatment device with the at least one tissue inside the nasal airway, with sufficient force to at least temporarily deform the at least one tissue, applying energy to, or removing energy from, the at least one tissue, using the treatment element, and removing the treatment element from the nostril. 1. A method of modifying at least one property of at least one tissue of or near a nasal valve of a nose , without using a surgical incision or an implant , to decrease airflow resistance or perceived airflow resistance in a nasal airway , the method comprising:contacting a treatment element of a treatment device with the at least one tissue inside the nasal airway, with sufficient force to at least temporarily deform the at least one tissue;applying energy to, or removing energy from, the at least one tissue, using the treatment element; andremoving the treatment element from the nostril.2. A method as in claim 1 , wherein the treatment element has a convex shape claim 1 , such that contacting the treatment element against the at least one tissue at least temporarily deforms the tissue into a concave shape.3. A method as in claim 2 , wherein contacting the treatment element with the tissue causes at least one protrusion on the treatment element to deform the tissue.4. A method as in claim 1 , wherein applying energy comprises applying energy in a form selected from the group consisting of ultrasound claim 1 , microwave claim 1 , heat claim 1 , radiofrequency claim 1 , electrical claim 1 , light and laser.5. A method as in claim 4 , wherein applying energy comprises delivering radiofrequency energy to one or more electrodes of the treatment element to locally heat the at least one ...

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Номер записи: 21
03-04-2014 дата публикации

COCHLEAR IMPLANT HEARING INSTRUMENT

Номер: US20140094864A1
Автор: Ambett Ranjeeta, Yanisse Daniel
Принадлежит: ADVANCED BIONICS AG

A hearing instrument for direct stimulation of the cochlea of a patient, comprising an audio signal source for providing audio signals, a sound processor for generating auditory nerve stimulation signals from the audio signals, a stimulation assembly to be implanted into the cochlea and comprising an electrode array to be located in the basal part of the cochlea for electrical stimulation of the auditory nerve in the basal part of the cochlea and a plurality of optical fibers extending beyond the electrode array into the apical part of the cochlea for optical stimulation of the auditory nerve in the apical part of the cochlea, and a driver unit for providing the stimulation assembly, according to the auditory nerve stimulation signals from the sound processor, with electric stimulation signals for the electrode array and with stimulation light from at least one light source for the optical fibers. 120-. (canceled)22. The hearing instrument of claim 21 , wherein the optical fibers are designed in such a manner that light emission points from where the stimulation light is emitted into the cochlea are spaced apart from each other along the apical part of the cochlea.23. The hearing instrument of claim 21 , wherein each light emission point is associated to a separate one of the optical fibers.24. The hearing instrument of claim 23 , wherein each light emission point is formed by the tip of the respective fiber claim 23 , with the optical fibers having different lengths.25. The hearing instrument of claim 21 , wherein the stimulation assembly comprises at least three of the optical fibers.26. The hearing instrument of claim 21 , wherein each fiber comprises a cladding made of polyimide.27. The hearing instrument of claim 21 , wherein the light source is for providing stimulation light having a wavelength from 1 to 2 μm.28. The hearing instrument of claim 21 , wherein the light source is for providing stimulation light having a power from 0.01 to 1 J/cm.29. The hearing ...

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Номер записи: 22
10-04-2014 дата публикации

PROCESS OF TOOTH WHITENING AND APPARATUS THEREFOR

Номер: US20140099603A1
Автор: Wasylucha Bryan
Принадлежит:

A process of whitening a tooth provided by the invention includes the steps of providing a delivery device for mechanical dispensing of a predetermined amount of a whitening composition to an applicator tip; dispensing the amount of whitening composition to the applicator tip; applying the amount of whitening composition disposed on the applicator tip to the tooth to be whitened; and allowing the whitening composition to remain in contact with the tooth for a period of time sufficient to whiten the tooth. Optionally, the process further includes the step of exposing the whitening composition to light. A gum or candy for tooth bleaching is detailed along with methods of use. A device adapted to dispense an amount of a dental whitening composition optionally includes a light source for activating the whitener. 1. A process of whitening a tooth , comprising the steps of:providing a delivery device for mechanically dispensing a predetermined amount of a whitening composition to an applicator tip;dispensing the amount of whitening composition to the applicator tip;applying the amount of whitening composition disposed on the applicator tip to a tooth to be whitened; andallowing the whitening composition to remain in contact with the tooth for a period of time sufficient to whiten a tooth.2. The process of claim 1 , wherein the predetermined amount ranges between 1-500 microliters.3. The process of claim 1 , wherein the predetermined amount ranges between 10-100 microliters.4. The process of claim 1 , further comprising the step of exposing the whitening composition to light.5. The process of claim 5 , wherein the whitening composition is exposed to light prior to applying the amount of whitening composition disposed on the applicator tip to the tooth to be whitened.6. The process of claim 5 , wherein the whitening composition is exposed to light after applying the amount of whitening composition disposed on the applicator tip to the tooth to be whitened.7. The process of ...

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Номер записи: 23
07-01-2016 дата публикации

MONITORING DISPOSITION OF TETHERED CAPSULE ENDOSCOPE IN ESOPHAGUS

Номер: US20160000312A1
Автор: Johnston Richard S., Seibel Eric J.
Принадлежит:

A scanning flexible endoscope includes a tether attached to a capsule. The tether controls a disposition of the capsule within a body lumen such as the esophagus. A scanning device in the capsule optically scans the adjacent tissue on the inside surface of the body lumen as the capsule is moved axially through the body lumen. A non-contact sensor responds to indicia on the tether to measure a relative position of the tether and the capsule in the body lumen. The indicia can be analog or digital in form and the sensor can be either magnetic, or optical. A wiper is optionally provided to remove bodily fluids from the tether when pulled from the body lumen past the sensor. A pulse of fluid can be delivered to the distal end of the tether to cause the body lumen to distend, facilitating free movement of the capsule in the lumen. 1. A method for imaging a body lumen of a patient , the method comprising:providing an imaging apparatus comprising a scanning capsule coupled to a flexible tether, the scanning capsule comprising a scanning device disposed within a capsule housing;introducing the scanning capsule and at least a portion of the flexible tether into the body lumen of the patient by swallowing, wherein the scanning capsule advances along the body lumen with normal peristalsis;scanning light onto a portion of the body lumen using the scanning device;detecting light from the portion of the body lumen using a light sensor;generating one or more images of the portion of the body lumen in response to the detected light;determining a rate for withdrawing the scanning capsule from the body lumen based on the one or more images; andwithdrawing the scanning capsule from the body lumen according to the determined rate.2. The method of claim 1 , further comprising stitching the one or more images together so as to generate a panoramic image of the portion of the body lumen.3. The method of claim 2 , wherein the stitching is performed using automated image stitching software.4 ...

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Номер записи: 24
06-01-2022 дата публикации

METHODS AND SYSTEMS FOR PHOTODYNAMIC THERAPY CALCULATIONS

Номер: US20220001193A1
Автор: YODH Arjun G., ZHU Timothy C.
Принадлежит:

Methods and systems are described for implementing a photodynamic therapy. An example method may comprise determining, during photodynamic therapy and using a plurality of optical probes spatially distributed within a patient, data indicative of one or more of a photodynamic therapy dosage, a fluence rate of a photodynamic therapy treatment light, or a reactive oxygen species concentration associated with corresponding locations of the plurality of optical probes. The example method may comprise changing, based on the data, one or more treatment parameters associated with providing a photodynamic therapy. 1. A method , comprising:determining, during photodynamic therapy and using a plurality of optical probes spatially distributed within a patient, data indicative of a reactive oxygen species concentration associated with corresponding locations of the plurality of optical probes; andchanging, based on the data, one or more treatment parameters associated with providing a photodynamic therapy.2. The method of claim 1 , further comprises determining claim 1 , during the photodynamic therapy and using the plurality of optical probes spatially distributed within the patient claim 1 , one or more of data indicative of a photodynamic therapy dosage or data indicative of a fluence rate of a photodynamic therapy treatment light.3. The method of claim 2 , wherein one or more of the data indicative of the photodynamic therapy dosage claim 2 , the data indicative of the fluence rate of the photodynamic therapy treatment light claim 2 , or the data indicative of a reactive oxygen species concentration are determined in parallel.4. The method of claim 1 , wherein the one or more treatment parameters comprise one or more of an intensity of the photodynamic therapy treatment light claim 1 , a location of the photodynamic therapy treatment light claim 1 , or a duration of photodynamic therapy treatment light.5. The method of claim 1 , further comprising:causing, during the ...

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Номер записи: 25
06-01-2022 дата публикации

LIGHT THERAPY TREATMENT METHOD AND APPARATUS

Номер: US20220001197A1
Автор: Huettemann Maik, Recanati Mauri ce-Andre, Sanderson Thomas H.
Принадлежит:

A method and apparatus for minimizing tissue adhesion in a tissue of a subject includes applying light, to the tissue, that reduces at least one adhesion marker in the tissue, the light having wavelengths in at least one of a first wavelength range of 730-770 nm and a second wavelength range of 930-970 nm, wherein the at least one adhesion marker includes at least one of a transforming growth factor beta 1 (TGF-β1), a vascular endothelial growth factor, (VEGF), and a collagen alpha-1(I) chain (COL|α|), and wherein the light is free of wavelengths that increase the at least one adhesion marker. 167-. (canceled)68. A method of minimizing tissue adhesion in a tissue of a subject , the method comprising:applying light, to the tissue, that reduces at least one adhesion marker in the tissue, the light having wavelengths in at least one of a first wavelength range of 730-770 nm and a second wavelength range of 930-970 nm, wherein the at least one adhesion marker includes at least one of a transforming growth factor beta 1 (TGF-β1), a vascular endothelial growth factor, (VEGF), and a collagen alpha-1(I) chain (COL1α1), and wherein the light is free of wavelengths that increase the at least one adhesion marker.69. The method of further comprising applying glycerol to the subject prior to applying the light to increase transparency of a skin of the subject to infrared light.70. The method of claim 68 , wherein the light is substantially free of 808 nm and 810 nm light to avoid increasing at least one of the at least one adhesion marker.71. The method of claim 68 , wherein the applied light is in the first wavelength range and the second wavelength range and is substantially free of light outside the first and second wavelength ranges to avoid increasing at least one of the at least one adhesion marker.72. The method of claim 68 , wherein the light has a first peak at approximately 750 nm and a second peak at approximately 950 nm.73. The method of claim 68 , wherein the light ...

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Номер записи: 26
07-01-2021 дата публикации

Apparatus for tissue irradiation and methods and kits utlizing the same

Номер: US20210001142A1
Автор: Irene E. Kochevar, Michael C. McCormack, Robert Redmond, William G. Austen
Принадлежит: General Hospital Corp

One aspect of the invention provides an apparatus including: a fluid-impermeable membrane configured to contain a fluid and be placed in the cavity; a light emitter provided within the membrane; and a fluid provided within the membrane, wherein the fluid scatters light emitted by the light emitter such that the intensity of the light is substantially uniform over the inner surface of the cavity proximal to the membrane.

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Номер записи: 27
07-01-2021 дата публикации

FOCAL PHOTODYNAMIC THERAPY METHODS

Номер: US20210001143A1
Автор: Abenhaim Lucien, Charbit Suzy, Gaillac Bertrand
Принадлежит:

Improved methods of treating prostate cancer by vascular-targeted photodynamic therapy, and improved methods of planning treatment, are presented using a light density index to plan and guide effective treatment. 132-. (canceled)33. A computer program product comprising a computer usable medium having computer readable program code embodied therein , the computer readable program code adapted to be executed by a computer to implement a method for producing a patient-specific treatment plan for photodynamic therapy of prostate cancer , the method comprising:setting the total length of illuminating fibers needed for effective therapy based upon the planned treatment volume (PTV) and a prior-determined treatment-effective light density index, LDI, threshold, wherein the treatment-effective LDI threshold is prior-determined from historical data from use of the same photosensitizing agent, andwherein the total length of illuminating fibers is calculated as the product of PTV and said prior-determined treatment-effective light density index threshold, or scalar multiple thereof.3435-. (canceled)36. The computer program product of claim 33 , wherein the treatment-effective LDI threshold is prior-determined from historical data from use of the same photosensitizing agent claim 33 , administered at the same systemic dosage.37. The computer program product of claim 36 , wherein the treatment-effective LDI threshold is prior-determined from historical data from use of the same photosensitizing agent claim 36 , administered at the same systemic dosage claim 36 , and same wavelength of delivered light.38. The computer program product of claim 37 , wherein the treatment-effective LDI threshold is prior-determined from historical data from use of the same photosensitizing agent claim 37 , administered at the same systemic dosage claim 37 , same irradiating light wavelength claim 37 , and same light density.39. An assistance method claim 37 , implemented by computer claim 37 , for ...

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Номер записи: 28
02-01-2020 дата публикации

PORTABLE RECHARGEABLE LED RED LIGHT CAVITY HEALING DEVICES

Номер: US20200001106A1
Автор: Ribeiro Adolfo, Sentis Nicole Kerstin
Принадлежит:

A light-emitting diode (LED) therapy device and method of use is provided that increases healing of tissues by targeting damaged tissue at a predetermined wavelength and pulsed at a predetermined frequency. The device includes a housing and a light radiation module enclosed within the housing. The light radiation module includes an LED, a controller unit connected to the LED to control wavelength and pulsed frequency of the LED, and a rechargeable power source. The device also includes a light-diffusing member connected to the housing designed to diffuse light emitted from the LED to damaged tissue in a human cavity. Light in the red or near infrared range and pulsed at a Nogier frequency increases the effectiveness of the LED device to stimulate healing of damaged tissues. Particular devices include incorporation into a pacifier for healing an infant's gums, or nasal, auditory, vaginal, or anal cavities and adults or children. 1. A light-emitting diode (LED) therapy device to target surfaces within a cavity , the device comprising:(i) a housing; (a) an LED for emitting light having at least one predetermined wavelength,', '(b) a controller unit connected to the LED, the controller unit capable of controlling pulse frequency of the LED for at least one predetermined frequency;', '(c) a power source electrically connected to the controller unit;, '(ii) a light radiation module substantially enclosed within the housing, the light radiation module having,'}(iii) a light diffusing member connected to the housing, the light diffusing member designed to diffuse and project light emitted from the LED.2. The device of claim 1 , and wherein the predetermined wavelength is between 600 nm and 700 nm claim 1 , and wherein the at least one predetermined frequency is at least one of a Nogier frequency and a harmonic of the Nogier frequency claim 1 ,whereby light pulsed at the Nogier frequency or the harmonic of the Nogier frequency increases the rate of tissue repair compared to ...

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Номер записи: 29
01-01-2015 дата публикации

Methods for thermally-induced renal neuromodulation

Номер: US20150005676A1
Автор: Benjamin J. Clark, Denise Zarins, Erik Thai, Howard R. Levin, Mark Gelfand, Nicolas Zadno
Принадлежит: Medtronic Ardian Luxembourg SARL

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.

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Номер записи: 30
20-01-2022 дата публикации

SYSTEM AND METHOD FOR LOW COST LIGHT THERAPY

Номер: US20220016436A1
Автор: Celli Jonathan P., Cuckov Filip, Hasan Tayyaba, Liu Hui, Rizvi Imran
Принадлежит:

A low-cost light delivery system includes a light source device and a light delivery applicator. The light source device includes a light source (e.g., a light emitting diode, a laser, or the like) mounted on a passive heat sink and coupled to an optical fiber extending out of the light source device to carry a light signal. The light source device also includes a microcontroller configured to define a required irradiance to be delivered by the light signal based on a prescribed dosimetry parameter; and one or more power sources, each configured to provide power to at least one of the high powered light emitting diode and the microcontroller. The light delivery applicator can be removably connected to the optical fiber and configured to be placed proximal to an area of the patient to deliver the required irradiance of the light signal to the area of the patient. 1. A system comprising: a light source mounted on a passive heat sink and coupled to an optical fiber extending out of the light source device, wherein the optical fiber delivers a light signal with a predefined optical power out of the light source device;', 'a microcontroller configured to define a required irradiance to be delivered by the light signal based on a prescribed dosimetry parameter; and', 'one or more power sources, each configured to provide power to at least one of the light source and the microcontroller; and, 'a light source device comprisinga light delivery applicator removably connected to the optical fiber and configured to be placed proximal to an area of the patient to deliver the required irradiance of the light signal to the area of the patient.2. The system of claim 1 , further comprising a portable computing device configured to wirelessly communicate with the light source device claim 1 ,wherein the portable computing device is configured to define a size of the area of the patient and the prescribed dosimetry to be delivered by the light signal and sends the prescribed dosimetry ...

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Номер записи: 31
14-01-2016 дата публикации

DEVICES AND METHODS FOR TREATMENT INSIDE A BODY CAVITY

Номер: US20160008624A1
Автор: Grossman Jessica D
Принадлежит:

A treatment device and method for transmitting UVC light energy within a patient's body cavity, the device having a distal end having a generally cylindrical shaped housing configured for insertion into the body cavity, a UVC light coupled to the housing configured to shine light radially outward from the housing; and a power source couple to the UVC light. 1. A treatment device for transmitting UVC light energy within a patient's body cavity comprising:a probe having a proximal and distal end, the proximal end having a handle and the distal end having a generally cylindrical shaped housing coupled to the handle, the cylindrical shaped housing being configured for insertion into the body cavity;one or more UVC light sources radiating light between 200-280 nm, UVC light being coupled to the housing configured to radiate the UVC light radially outward from the housing; anda power source couple to the one or more UVC light sources.2. The treatment device of claim 1 , wherein the housing is a transparent housing made of a UVC transmissive material and the UVC light is positioned within the transparent housing3. The treatment device of claim 1 , wherein the UVC light is positioned on a surface of the housing.4. The treatment device of claim 1 , wherein an outer surface of the housing is part of the UVC light.5. The treatment device of claim 1 , wherein the UVC light is selected from the group consisting of: an excimer laser claim 1 , a laser diode claim 1 , dye laser claim 1 , metal halide lamp claim 1 , UV LED claim 1 , cold cathode fluorescent lamp (or other fluorescent light source) claim 1 , flashlamp claim 1 , microwave generated UV plasma claim 1 , and the like.6. The treatment device of claim 1 , wherein the housing is flexible.7. The treatment device of claim 1 , wherein the housing is rigid.8. The treatment device of claim 1 , further comprising a controller coupled to the one or more UVC light sources claim 1 , the controller being configured to control the ...

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Номер записи: 32
11-01-2018 дата публикации

Light therapy delivery devices and methods for the female genitalia and areas proximal thereto

Номер: US20180008837A1
Автор: Jack K. Zhang
Принадлежит: Z2020 LLC

The present invention relates to light therapy devices and related methods to treat the female genitalia and areas proximal thereto, including the vaginal cavity and vulvar regions in cisgender females or transgender females who have undergone sex reassignment, in particular for post-surgical indications, vaginal rejuvenation, or other medical conditions suitable for treatment with light therapy. The devices and methods are configured to provide a therapeutic amount of low level light therapy to a patient in need of treatment thereof.

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Номер записи: 33
14-01-2021 дата публикации

TOOTH WHITENING DEVICE

Номер: US20210008384A1
Автор: LEE Soon Ho
Принадлежит:

Provided is a tooth whitening device capable of performing tooth whitening treatment. The tooth whitening device can be disposable. The tooth whitening device comprises: a main frame provided in a horseshoe shape and having a whitening groove in which teeth can be fitted; a support member coupled to the main frame; a plurality of light-emitting members installed inside the main frame and configured to emit light during tooth whitening; a fluid storage member positioned to extend through the insides of the main frame and the support member, and configured to store a fluid such as saliva flowing out of the mouth during the tooth whitening; and a control member for controlling a light-emitting time or operation of the light-emitting member, wherein the whitening groove is coated with a gel-type whitener. 1. A disposable tooth whitening device comprising:a main frame provided in a horseshoe shape and comprising tooth whitening grooves capable of holding teeth;a support member coupled with the main frame;a plurality of light emitting members installed in the main frame and configured to emit light during tooth whitening;a fluid storage member located to pass through the main frame and an inside of the support member and configured to store saliva and the like flowing from an inside of a mouth during the tooth whitening; anda control member configured to control a light emission time of the light emitting members and whether the light emitting members operate,wherein a gel type tooth whitening agent is applied to the tooth whitening grooves.2. The tooth whitening device of claim 1 , wherein the main frame comprises:an inner frame provided in a horseshoe shape;an outer frame provided in a horseshoe shape and located to be spaced apart from the inner frame; anda bottom frame coupled with the inner frame and the outer frame and located between the inner frame and the outer frame.3. The tooth whitening device of claim 2 , wherein the tooth whitening grooves are provided to be ...

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Номер записи: 34
09-01-2020 дата публикации

METHODS OF TREATING SKIN CANCER BY ADMINISTERING A PD-1 INHIBITOR

Номер: US20200010538A1
Автор: Fury Matthew G., Lowy Israel
Принадлежит:

The present invention provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., skin cancer). The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a programmed death 1 (PD-1) antagonist (e.g., an anti-PD-1 antibody). In certain embodiments, the skin cancer is cutaneous squamous cell carcinoma or basal cell carcinoma. 1. A method of treating or inhibiting the growth of a tumor comprising:(a) selecting a patient with a skin cancer; and(b) administering to the subject in need thereof a therapeutically effective amount of an antibody or antigen-binding fragment thereof that specifically binds PD-1; wherein the anti-PD-1 antibody or antigen-binding fragment thereof comprises the heavy chain complementarity determining regions (HCDR1, HCDR2 and HCDR3) of a heavy chain variable region (HCVR) comprising the amino acid sequence of SEQ ID NO: 1 and three light chain complementarity determining regions (LCDR1, LCDR2 and LCDR3) of a light chain variable region (LCVR) comprising the amino acid sequence of SEQ ID NO: 2.2. The method of claim 1 , wherein the anti-PD-1 antibody is administered as a monotherapy.3. The method of claim 1 , wherein said skin cancer is an UV-associated skin cancer.4. The method of claim 1 , wherein said skin cancer is selected from the group consisting of cutaneous squamous cell carcinoma (CSCC) claim 1 , basal cell carcinoma (BCC) claim 1 , Merkel cell carcinoma and melanoma.5. The method of claim 1 , with the proviso that said skin cancer is not a squamous cell carcinoma of head and neck.6. The method of claim 1 , wherein said skin cancer is a metastatic claim 1 , unresectable and/or locally advanced cancer.7. The method of claim 6 , wherein said skin cancer is BCC claim 6 , and wherein said patient is intolerant to or progresses after treatment with a hedgehog pathway inhibitor.8. The method of claim 6 , wherein said skin cancer is CSCC ...

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Номер записи: 35
17-01-2019 дата публикации

Light Emitting Oral Care Implement

Номер: US20190014901A1
Автор: Guo Guang Sheng, Xi Wen Jin, XIE Fan Gang, ZHANG BO, Zhou Jian Rong
Принадлежит: Colgate-Palmolive Company

An oral care product array includes a handle component and multiple refill components therefor. The handle component includes a power source. A first refill component includes a first light generating module which emits light in a first spectrum from the first refill component. A second refill component includes a second light generating module which emits light in a second spectrum from the second refill component. Each refill component has a coupled state, when coupled to the handle component, and a decoupled state, when decoupled from the handle component. When the first refill component is in the coupled state, the first light generating module is powered by the power source to emit light in the first spectrum. When the second refill component is in the coupled state, the second light generating module is powered by the power source to emit light in the second spectrum. 1. An oral care product array comprising:a handle component comprising a power source;a first refill component comprising a first light generating module configured to emit light in a first spectrum from the first refill component; anda second refill component comprising a second light generating module configured to emit light in a second spectrum from the second refill component, the second spectrum being different than the first spectrum;the first refill component alterable between: (1) a decoupled state in which the first refill component is separated from the handle component; and (2) a coupled state in which the first refill component is mounted to the handle component and the first light generating module is powered by the power source to emit light in the first spectrum from the first refill component; andthe second refill component alterable between: (1) a decoupled state in which the second refill component is separated from the handle component; and (2) a coupled state in which the second refill component is mounted to the handle component and the second light generating module is ...

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Номер записи: 36
17-01-2019 дата публикации

PHOTOTHERAPY DEVICES AND METHODS

Номер: US20190015185A1
Автор: Hébert Lise, Loupis Nikolaos, Piergallini Remigio
Принадлежит:

The present disclosure relates to a phototherapy device that can deliver light to tissues to activate photoactive agents that have been applied to the tissues or that are included within a fiber optic tip member of the device which may be coupled to a light source using a sleeve. The present disclosure also relates to methods of phototherapy using the phototherapy device such as anti-bactericidal treatment, anti-fungal treatment, anti-parasitic treatment, anti-viral treatment. 151.-. (canceled)52. A method for phototherapeutic treatment of a treatment region , the method comprising:a) applying a composition comprising a photoactivating agent into the treatment region;b) introducing an optic member into the treatment region; andc) applying light through the optic member to activate the photoactivating agent in the treatment region.53. A method as defined in claim 52 , wherein the optic member has a length having a proximal end and a distal end.54. A method as defined in claim 53 , wherein the proximal end is configured to be operatively coupled to a light source.55. A method as defined in claim 53 , wherein the distal end is configured for introduction into the treatment region.56. A method as defined in claim 53 , wherein the optic member functions as a waveguide and transmits light along the length of the optic member.57. A method as defined in claim 55 , wherein the distal end comprises a plurality of bristles.58. A method as defined in claim 52 , wherein the optic member has a polymer core.59. A method as defined in claim 52 , wherein the optic member is flexible.60. A method as defined in claim 52 , wherein the treatment region is a wound.61. A method as defined in claim 52 , wherein the treatment region is an internal tissue.62. A method as defined in claim 52 , wherein the photoactivating agent is one or more of a xanthene derivative dye claim 52 , an azo dye claim 52 , a biological stain or a carotenoid.63. A method as defined in claim 61 , wherein the ...

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Номер записи: 37
18-01-2018 дата публикации

Method, System and Apparatus for Non-Invasive Neurostimulation Therapy of the Brain

Номер: US20180015301A1
Автор: LIM Lew
Принадлежит:

The present invention is a portable non-invasive system, apparatus and method for performing light therapy or photobiomodulation upon the brain tissues through the skull and/or nostrils of a living mammalian subject for the medical purpose of stimulating the brain in-vivo. The present invention utilizes the transcranial and/or intranasal pathways as points of anatomic access and follows established principles for the conceptual approach that irradiation of the brain tissue with low level light energy of certain fixed parameters would achieve major therapeutic effects in-vivo. 1. A self-administrable system for performing non-invasive neurostimulation therapy of the brain of a living mammal on-demand , said self-administrable non-invasive neurostimulation system comprising: (i) a light energy transmitting material which forms at least a portion of the configured external surface for said hollow casing of each configured irradiation unit; and', '(ii) at least one light generating unit housed and contained within said internal spatial volume of said hollow casing of each configured irradiation unit and which is capable of generating light energy of at least one preselected wavelength selected from the group consisting of near infrared red light wavelengths and visible red light wavelengths, at a predetermined energy intensity and for a preset time duration on-demand sufficient to penetrate through the skull and to pass into the brain,, 'first, second, third and fourth configured irradiation units, each of said first, second, third and fourth configured irradiation units comprising a portable hollow casing having fixed dimensions, a sized internal spatial volume and an external surface configuration suitable for application to the skull, said portable hollow casing of each configured irradiation unit being comprised ofwhereby said first, second, third and fourth configured irradiation units can emit light energy after application to the skull and achieve passage of said ...

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Номер записи: 38
15-01-2015 дата публикации

HANDHELD LASER DEVICE FOR MEDICAL PURPOSES

Номер: US20150017599A1
Автор: Leskovar Marko, Marincek Marko, Perhavec Tadej, Zabkar Janez
Принадлежит:

A handheld laser device for medical, in particular dental treatment purposes, comprising a handpiece having a handpiece body accommodating a laser and a removable handpiece attachment. The handpiece attachment is slidable over at least a major portion of the handpiece body and the device is adapted such that air and/or water can be supplied from the handpiece body to the handpiece attachment. 1. A handheld laser device for medical , in particular dental treatment purposes , comprising a handpiece having a handpiece body accommodating a laser and a removable handpiece attachment , wherein the handpiece attachment is slidable over at least a major portion of the handpiece body and wherein air and/or water is supplied from the handpiece body to the handpiece attachment.2. The handheld laser device according to claim 1 , wherein the handpiece attachment is adapted to be rotatable relative to the handpiece body claim 1 , to allow at least two different angular working orientations.3. The handheld laser device according to claim 1 , comprising a ring-shaped spring element assigned to the handpiece body offering a radial bias to provide a latch-type fixation for coupling the handpiece body and the handpiece attachment.4. The handheld laser device according to claim 3 , wherein the ring-shaped element is arranged on the handpiece body and comprises an annular locking ridge on its outer surface and the handpiece attachment is slidable over said annular locking ridge and comprises a corresponding annular locking recess to interact with said annular locking ridge claim 3 , and/or wherein the ring shaped element is arranged on the handpiece body and comprises an annular locking recess on its outer surface and the handpiece attachment comprises a corresponding annular locking projection to interact with said annular locking recess.5. The handheld laser device according to claim 1 , wherein the handpiece body comprises an annular groove and a supply conduit for air and/or water; ...

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Номер записи: 39
16-01-2020 дата публикации

ENDOSCOPES AND METHODS OF TREATMENT

Номер: US20200016425A1
Автор: DING WEIJIANG, LI YUANXUN, LU Yancong
Принадлежит:

An endoscope includes a handle, an elongated body extending distally from the handle and defining a longitudinal axis, a light source disposed within the distal portion of the elongated body and configured to illuminate tissue, and a therapeutic unit disposed within the distal portion of the elongated body and configured to treat tissue. 1. An endoscope comprising:a handle;an elongated body extending distally from the handle and defining a longitudinal axis, the elongated body including a distal portion;a light source disposed within the distal portion of the elongated body and configured to illuminate tissue; anda therapeutic unit disposed within the distal portion of the elongated body and configured to treat tissue.2. The endoscope according to claim 1 , wherein the therapeutic unit includes a plurality of LED elements.3. The endoscope according to claim 1 , further comprising a controller disposed in electrical communication with the light source and with the therapeutic unit.4. The endoscope according to claim 1 , further comprising an image sensor disposed within the distal portion of the elongated body and configured to capture a plurality of images.5. The endoscope according to claim 1 , wherein the therapeutic unit produces light energy.6. The endoscope according to claim 5 , wherein the therapeutic unit is configured to focus the light energy on an area of tissue that is smaller than an area of tissue illuminated by the light source.7. The endoscope according to claim 1 , wherein the therapeutic unit includes a light emitting element and a lens.8. The endoscope according to claim 7 , wherein the lens includes a proximal surface and a distal surface claim 7 , the proximal surface disposed at first angle with respect to a first axis claim 7 , the distal surface disposed at a second angle with respect to the second axis claim 7 , the first angle is between about 5° and about 15° claim 7 , the second angle is between about 5° and about 15° claim 7 , the first ...

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Номер записи: 40
16-01-2020 дата публикации

METHOD AND APPARATUS FOR TOOTH REGULATION WITH HEAVY FORCES

Номер: US20200016426A1
Автор: Brawn Peter Robert
Принадлежит: Biolux Research Holdings, Inc.

Methods are provided for regulating tooth movement and for maintaining or improving tissue health using heavy forces. Such methods comprise allowing a heavy force to be exerted on one or more teeth of a patient in need thereof; and administering an effective amount of light to the maxillary or mandibular alveolar bone of the patient, wherein the light is administered before, during, or after the heavy force is exerted. The light can have a wavelength in the range of about 585 nm to about 665 nm, or about 815 nm to about 895 nm. An apparatus useful for providing light therapy is also provided. 128.-: (canceled)29. An intra-oral light therapy system , comprising:an oral tray configured to fit within an oral cavity of a patient;a plurality of emitters embedded within the oral tray and configured to overlie and irradiate mucosal tissue overlying a root of a tooth of the patient when in use in the oral cavity; and{'sup': 2', '2, 'a controller comprising instructions to irradiate the root of the tooth of the patient at a wavelength ranging from 620 nm to 1,000 nm and an intensity ranging from about 1 mW/cmto about 100 mW/cm.'}30. An intra-oral light therapy system , comprising:an oral tray configured to fit within an oral cavity of a patient;{'sup': 2', '2, 'a plurality of emitters embedded within the oral tray and configured to overlie and irradiate mucosal tissue overlying one or more roots of a plurality of teeth of the patient when in use in the oral cavity wherein each of the plurality of emitters is configured to emit light having a wavelength ranging from 620 nm to 1,000 nm and an intensity ranging from about 50 mW/cmto about 200 mW/cm; and'}a controller comprising instructions to activate the plurality of emitters according to a treatment regimen in response to the patient initiating a treatment session.31. An intra-oral light therapy system , comprising:an oral tray configured to fit within an oral cavity of a patient;a plurality of emitters embedded within the ...

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Номер записи: 41
28-01-2016 дата публикации

Ultrasound apparatuses for thermally-induced renal neuromodulation and associated systems and methods

Номер: US20160023022A1
Автор: Benjamin J. Clark, Denise Zarins, Erik Thai, Howard R. Levin, Mark Gelfand, Nicolas Zadno
Принадлежит: Medtronic Ardian Luxembourg SARL

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.

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Номер записи: 42
25-01-2018 дата публикации

NASOLACRIMAL IMPLANTS AND RELATED METHODS FOR TEAR STIMULATION

Номер: US20180021171A1
Автор: Kahook Malik Y.
Принадлежит:

A device for inducing production of tears may include a body extending from a proximal end to a distal end. The body may be configured for insertion through a puncta of a subject. The device also may include a stimulus delivery mechanism positioned between the proximal end and the distal end and an induction coil operably coupled to the stimulus delivery mechanism. Further, the device may include an external controller wirelessly coupled to the induction coil for inductively transferring energy to the induction coil. 130-. (canceled)31: A device for inducing tears in a subject , comprising:a body extending from a proximal end to a distal end, the body further including an expandable component configured to expand into conformity with the anatomical features of a lacrimal sac of the subject when the device is inserted therein; anda stimulus delivery mechanism positioned between the proximal end and the distal end.32: The device of claim 31 , further comprising a power receptor disposed on or within the body.33: The device of claim 32 , wherein the power receptor is comprised of a photo-active material.34: The device of claim 31 , further including a sensor configured for sensing one or more of biochemical properties of tears claim 31 , placement of the body claim 31 , and operation of the stimulus delivery mechanism.35: The device of claim 34 , wherein the sensor is configured to detect a degree of conductivity in the lacrimal sac of the subject.36: A method for inducing tears in a subject claim 34 , comprising:positioning a portion of the stimulation delivery device in a nasolacrimal sac of the subject; andapplying a stimulation signal to the nasolacrimal sac via the stimulation delivery device, the stimulation signal being received via a power receptor associated with the stimulation delivery device to induce tearing in the subject.37: The method of claim 36 , wherein prior to the step of positioning a portion of the stimulation delivery device in a nasolacrimal ...

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Номер записи: 43
10-02-2022 дата публикации

MULTI-PHASE ORAL COMPOSITION FOR DELIVERING ORAL CARE ACTIVE AGENTS

Номер: US20220040061A1
Автор: RAJAIAH Jayanth, SAGEL Paul Albert
Принадлежит:

A multi-phase oral composition for delivering active agents. 1. A multi-phase oral composition for delivering one or more active agents comprising:a) from about 0.002% to about 50% by weight of the multi-phase oral composition of an aqueous phase having an active agent;b) a hydrophobic phase;wherein the ratio of the concentration in weight percent of active agent present in the aqueous phase to the concentration in weight percent of active agent present in the overall multi-phase oral composition is at least 5;wherein the concentration of the active agent is up to about 20% by weight of the multi-phase oral composition; andwherein the hydrophobic phase is a predominant portion of the multi-phase oral composition.2. The multi-phase oral composition according to claim 1 , wherein the ratio of the concentration in weight percent of active agent present in the aqueous phase to the concentration in weight percent of active agent present in the overall multi-phase oral composition is at least about 10.3. The multi-phase oral composition according to claim 2 , wherein the ratio of the concentration in weight percent of active agent present in the aqueous phase to the concentration in weight percent of active agent present in the overall multi-phase oral composition is at least about 15.4. The multi-phase oral composition according to claim 1 , wherein the amount of the active agent ranges from about 1% to about 10% by weight of the multi-phase oral composition.5. The multi-phase oral composition according to claim 1 , wherein the cone penetration consistency value of the hydrophobic phase or the multiphase oral composition is from about 100 to about 500 claim 1 , as measured by ASTM D937-07.6. The multi-phase oral composition according to claim 5 , wherein the cone penetration consistency value of the hydrophobic phase or the multiphase oral composition is from about 100 to about 300 claim 5 , as measured by ASTM D937-07.7. The multi-phase oral composition according to ...

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Номер записи: 44
10-02-2022 дата публикации

STOMATITIS TREATMENT DEVICE

Номер: US20220040495A1
Автор: HWANG Kyong Won, MOON Pyoung Su
Принадлежит:

A stomatitis treatment device which is equipped with a light emitting means inside a housing to enable inflammations on the roof of the mouth and the upper side of the tongue to be treated, and to which a coupling module is attached to allow inflammations occurring on the lower side of the bottom of the mouth, etc. to be treated, is proposed. The stomatitis treatment device allows the roof of the mouth, the tongue, and the bottom of the mouth to be simultaneously irradiated with light for treatment by attaching and detaching the coupling module to and from the housing having the cell regeneration lamp therein, and thus can be used by patients having severe stomatitis with multiple lesions. 1. A stomatitis treatment device comprising:a housing inserted into an oral cavity and mounted on a palate and a top side of a tongue;a body comprising the housing and a connection portion;a cell restoration lamp provided inside the housing and configured to output a near-infrared ray;an external device configured to supply power to the cell restoration lamp; anda coupling module coupled to the housing, mounted on a bottom side of the tongue and a floor of a mouth, and comprising a light transfer body,wherein it is possible to output near-infrared rays to the palate, the top side of the tongue, the bottom side of the tongue, and the floor of the mouth at the same time.2. The stomatitis treatment device of claim 1 , wherein the housing comprises a first upper portion formed to be convex to be mounted on the palate and a first lower portion formed to be concave to be mounted on the top side of the tongue claim 1 , andwherein the first lower portion comprises a plurality of coupling grooves formed at a distance of 5 mm to 10 mm from an apex of the tongue mounted thereon.3. The stomatitis treatment device of claim 2 , wherein the light transfer body is embedded in and protrudes from the coupling module claim 2 , andwherein the coupling module comprises a second upper portion formed to ...

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Номер записи: 45
10-02-2022 дата публикации

INTERNAL ULTRAVIOLET THERAPY

Номер: US20220040497A1
Автор: Leite Gabriela Guimaraes Sousa, MATHUR Ruchi, Melmed Gil Y., Pimentel Mark, REZAIE Ali
Принадлежит: CEDARS-SINAI MEDICAL CENTER

A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway. 1. A system for performing intra-corporeal ultraviolet therapy , the system comprising:a delivery tube adapted to be positioned inside of an endotracheal (ET) tube; andat least one ultraviolet (UV) light source inside the delivery tube positioned to deliver UV light outward from the delivery tube, wherein the at least one UV light source is configured to emit the UV light at wavelengths between 335 nm and 350 nm.2. The system of claim 1 , wherein the at least one UV light source is a narrowband UV light source configured to emit wavelengths between 335 nm and 350 nm.3. The system of claim 1 , wherein the delivery tube is at least partially transparent.4. The system of claim 1 , wherein the UV light source is a string of LED light sources.5. The system of claim 4 , wherein the string of LED light sources is configured to emit the UV light at a peak wavelength of between 335 nm and 350 nm.6. The system of claim 4 , wherein the string of LED light sources is configured to emit the UV light at a peak wavelength of between 338 nm and 342 nm.7. The system of claim 1 , wherein the UV light source is configured to deliver the UV light around the circumference of the delivery tube.8. The system of claim 1 , further comprising a power supply connected to the UV light source.9. The system of claim 1 , wherein the UV light source is configured to deliver the UV light along a substantial length of the delivery tube.10. The system of claim 1 , wherein the delivery tube is a catheter.11. The system of ...

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Номер записи: 46
17-04-2014 дата публикации

Systems, methods and devices for performing gynecological procedures

Номер: US20140107404A1
Автор: William Harwick Gruber
Принадлежит: Hologic Inc

Systems, methods, apparatus and devices for performing improved gynecologic and urologic procedures are disclosed. The system and devices provide simplified use and reduced risk of adverse events. Patient benefit is achieved through improved outcomes, reduced pain, especially peri-procedural pain, and reduced recovery times. The various embodiments enable procedures to be performed outside the hospital setting, such as in a doctor's office or clinic.

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Номер записи: 47
23-01-2020 дата публикации

METHOD AND APPARATUS FOR TOOTH REGULATION WITH HEAVY FORCES

Номер: US20200023191A1
Автор: Brawn Peter Robert
Принадлежит: Biolux Research Holdings, Inc.

Methods are provided for regulating tooth movement and for maintaining or improving tissue health using heavy forces. Such methods comprise allowing a heavy force to be exerted on one or more teeth of a patient in need thereof; and administering an effective amount of light to the maxillary or mandibular alveolar bone of the patient, wherein the light is administered before, during, or after the heavy force is exerted. The light can have a wavelength in the range of about 585 nm to about 665 nm, or about 815 nm to about 895 nm. An apparatus useful for providing light therapy is also provided. 1. A method for reducing or preventing tooth root resorption caused by orthodontic treatment with an orthodontic appliance , comprising:exerting, using an orthodontic appliance, a force on a tooth of a subject undergoing orthodontic treatment with the orthodontic appliance and in need of reduction or prevention of tooth root resorption; and{'sup': 2', '2, 'administering, via a light-therapy apparatus, light to soft tissue supporting the tooth, wherein the light has a wavelength ranging from about 620 nm to about 1000 nm and an intensity ranging from about 1 mW/cmto about 10 W/cm.'}2. The method of claim 1 , wherein the administering occurs for a duration of at least one minute and after the exerting.3. The method of claim 1 , wherein the administering occurs for a duration of at least one minute and prior to the exerting.4. The method of claim 1 , wherein the administering occurs during a first time period claim 1 , the first time period commencing prior to the exerting claim 1 , and during a second time period claim 1 , the second time period commencing at a time during the exerting or at a time after the exerting.5. The method of claim 1 , wherein the administering occurs for a duration of at least ten minutes and prior to the exerting.6. The method of claim 1 , wherein the administering occurs once per day for a predetermined finite minimum period of time.7. The method of ...

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Номер записи: 48
28-01-2021 дата публикации

Phototherapy method

Номер: US20210023386A1
Автор: Tomohiko MAMIYA
Принадлежит: Olympus Corp

A phototherapy method includes: introducing an ultrasound endoscope into a digestive tract; visualizing an irradiation target site in a body by means of the ultrasound endoscope introduced into the digestive tract; puncturing a vicinity of the irradiation target site with a distal-end section of a needle tube that is made to protrude from a distal-end section of the ultrasound endoscope introduced into the digestive tract; exposing an optical fiber from the distal-end section of the needle tube that has punctured the vicinity of the irradiation target site, by making the needle tube retreat with respect to the optical fiber accommodated inside the needle tube; and radiating light emitted from the exposed optical fiber onto the irradiation target site.

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Номер записи: 49
02-02-2017 дата публикации

At-Home Light-Emitting Diode and Massage Device for Vaginal Rejuvenation

Номер: US20170028213A1
Автор: Andersen Roger, Bailey Kevin, Bailey Matthew, Courtion Colette, Klimava Yana, Loebel Nicolas
Принадлежит:

A light emitting module and massage device provide vaginal rejuvenation. The device exposes collagen in the vaginal area or mucosa to temperatures elevated over normal body temperature to cause the collagen to reversibly or irreversibly denature while simultaneously applying vibration. Once thermally-induced collagen denaturation has occurred, both neoelastogenesis and neocollagenesis may occur and may be initiated with fibroblast proliferation, which may be promoted with vibration. Neofibrogenesis also occurs due to the fibroblastic activity, responsible for secretion of new collagen matrix to effect tissue repair. Thus, the device exploits thermally-induced collagen denaturation and repair along with simultaneous vibration to improve tissue tone, connective tissue tension and bulk tissue regeneration. 1. A rejuvenation and massage device comprising:an insertable device having at least one contact surface and being insertable into a vagina;a light emitting mechanism integrated within the insertable device, the light emitting mechanism comprising one or more light emitters arranged around a portion of the insertable device that is insertable into the vagina, the one or more light emitters configured to emit light onto tissue within the vagina;a safety temperature mechanism integrated within the insertable device;a vibration mechanism integrated within the insertable device configured to provide vibration to the tissue within the vagina to induce a pleasure response and tone muscle;a power source associated with the insertable device;a controller configured to communicate with the insertable device coupled to the light emitting mechanism, safety temperature mechanism, vibration mechanism, and power source; anda user interface coupled to the controller and accessible by a user, the controller configured to receive feedback from the user using the user interface.2. The device of claim 1 , further comprising a cooling mechanism claim 1 , the cooling mechanism integrated ...

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Номер записи: 50
02-02-2017 дата публикации

SYSTEMS AND METHODS FOR PHOTOTHERAPEUTIC MODULATION OF NITRIC OXIDE

Номер: US20170028214A1
Автор: JR. Nicholas William, Medendorp, Negley Gerald H., Reighard Katelyn P., Stasko Nathan
Принадлежит:

Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm. 1. A method of modulating nitric oxide in living mammalian tissue , the method comprising:impinging light having a first peak wavelength on the tissue at a first radiant flux, wherein the first peak wavelength and the first radiant flux are selected to release nitric oxide from endogenous stores of nitric oxide; andimpinging light having a second peak wavelength on the tissue at a second radiant flux, wherein the second peak wavelength and the second radiant flux are selected to stimulate enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, wherein the second peak wavelength is greater than the first peak wavelength by at least 25 nm.2. The method of claim 1 , wherein the second peak wavelength is greater than the first peak wavelength by at least 50 nm.3. The method of claim 1 , wherein each of the first radiant flux and the second radiant flux is in a range of at least 5 mW/cm.4. The method of claim 1 , wherein each of the first radiant flux and the second radiant flux is in a range of from 5 mW/cmto 60 mW/cm.5. The method of claim 1 , wherein the enzymatic generation of nitric oxide is mediated by iNOS claim 1 , nNOS claim 1 , and/or eNOS in or proximate to the tissue.6. The method of claim 1 , wherein the endogenous stores of nitric oxide comprise nitros oglutathione claim 1 , nitro so albumin claim 1 , nitros ohemoglobin ...

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Номер записи: 51
24-04-2014 дата публикации

Handpiece Assembly for Laser Treatment Device

Номер: US20140113243A1
Автор: Boutoussov Dmitri, Kojima Rolf G.
Принадлежит: BIOLASE, Inc.

A handpiece assembly for laser treating a target surface and a laser system are disclosed. A handpiece assembly for laser treating a target surface includes a cable connector that is detachably coupled to a power supply and control module. The cable connector is configured to receive power and control signals from the power supply and control module. The handpiece assembly includes a laser module configured to receive the power and control signals from the cable connector and to generate electromagnetic energy based on the received power and control signals. The laser module is a replaceable module that is detachably coupled to the cable connector and a handpiece. The replaceable module allows a particular laser module to be removed from the handpiece assembly and replaced with another laser module. The handpiece assembly further includes the handpiece configured to receive the electromagnetic energy from the laser module and to direct the electromagnetic energy to the target surface. 1. A handpiece assembly for laser treating a target surface , the handpiece assembly comprising:a cable connector that is detachably coupled to a power supply and control module, the cable connector being configured to receive power and control signals from the power supply and control module;a laser module configured to receive the power and control signals from the cable connector and to generate electromagnetic energy based on the received power and control signals, the laser module being a replaceable module that is detachably coupled to the cable connector and a handpiece to allow the laser module to be removed from the handpiece assembly, the replaceable module allowing a particular laser module to be removed from the handpiece assembly and replaced with another laser module; andthe handpiece configured to receive the electromagnetic energy from the laser module and to direct the electromagnetic energy to the target surface.2. The handpiece assembly of claim 1 , wherein the ...

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Номер записи: 52
24-04-2014 дата публикации

Tooth whitening composition containing colloidal platinum

Номер: US20140113244A1
Автор: Shinichi Katou, Toshikazu Shiba, Yumi Kawazoe
Принадлежит: RegeneTiss Inc

A tooth whitening composition with a high level of whitening effectiveness over the entire tooth whitening composition application includes colloidal platinum as a platinum catalyst in a peroxide-containing oral composition. Whitening effectiveness can be enhanced by application of a tooth whitening composition containing colloidal platinum to the teeth surface followed by photo-irradiation of the application site.

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Номер записи: 53
30-01-2020 дата публикации

Multi-Electrode Apposition Judgment Using Pressure Elements

Номер: US20200030028A1
Автор: Srivastava Nishant R.
Принадлежит:

Apparatus and methods for determining positioning of a energy delivery element include deploying a energy delivery element at a treatment site proximal to a vessel wall; using a multi-region pressure sensing apparatus to sense pressures applied in a plurality of directions about the energy delivery element; and determining an orientation of the energy delivery element based on the pressures measured in the plurality of directions about the energy delivery element. 1. An apparatus for measuring blood pressure of a patient during a neuromodulation treatment , comprising:a therapeutic assembly configured for intravascular delivery to a treatment site;an energy delivery element disposed on the therapeutic assembly and configured to be positioned against a vessel wall to deliver neuromodulation energy at the treatment site; anda pressure sensor having a plurality of pressure sensitive regions, the pressure sensor being configured to measure the blood pressure of the patient.2. The apparatus of claim 1 , wherein the pressure sensor includes a first conductive annular ring claim 1 , a second conductive annular ring and a plurality of non-conductive areas on the second conductive annular ring.3. The apparatus of claim 1 , wherein the plurality of pressure sensitive regions are configured to sense pressure in a plurality of directions about the energy delivery element.4. The apparatus according to claim 1 , wherein the energy delivery element includes a plurality of energy delivery elements.5. The apparatus according to claim 1 , wherein the pressure sensor includes a capacitive pressure sensor.6. The apparatus according to claim 1 , wherein the therapeutic assembly includes an elongated support structure configured to take a pre-determined shape upon deployment in a vessel claim 1 , wherein the energy delivery element is disposed in a predetermined orientation on the elongated support structure.7. The apparatus according to claim 6 , wherein the elongated support structure ...

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Номер записи: 54
11-02-2016 дата публикации

Light Emitting Toothbrush

Номер: US20160038762A1
Автор: Lin Hungwei
Принадлежит:

The present invention provides an improved light emitting toothbrush having an angular head removably secured to a base, wherein said base includes an operator for operating the light emitting toothbrush and an electronic power supply for powering said light emitting toothbrush, said angular head adapted for use with a radiation responsive paste applied to a tooth surface for simultaneous removal of bacteria and whitening of the tooth surface a plurality of fiber optic bristles extending from a front brush face of the angular head and in optical communication with a light emitter, said plurality of fiber optic bristles being generally adapted for conducting the emitted radiation from said light emitter towards the tooth surface. 1. An improved light emitting toothbrush having an angular head removably secured to a base , wherein said base includes an operator for operating the light emitting toothbrush and an electronic power supply for powering said light emitting toothbrush , said angular head adapted for use with a radiation responsive paste applied to a tooth surface for simultaneous removal of bacteria and whitening of the tooth surface , said improvement comprising:a plurality of fiber optic bristles extending from a front brush face of the angular head and in optical communication with a light emitter, said plurality of fiber optic bristles being generally adapted for conducting the emitted radiation from said light emitter towards the tooth surface;said plurality of fiber optic bristles grouped into a fiber optic bundle which extends along a central shaft of the angular head with the plurality of fiber optic bristles spacing outwardly through a manifold;an optical socket in optical communication with said fiber optic bundle and said light emitter,an optical channel extending from said light emitter for connection to said optical socket for transmitting the emitted radiation from said light emitter housed by said base to said angled head; andsaid manifold ...

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Номер записи: 55
08-02-2018 дата публикации

NASOLACRIMAL IMPLANTS AND RELATED METHODS FOR TEAR STIMULATION

Номер: US20180036169A1
Автор: Kahook Malik Y.
Принадлежит:

A device for inducing production of tears may include a body extending from a proximal end to a distal end. The body may be configured for insertion through a puncta of a subject. The device also may include a stimulus delivery mechanism positioned between the proximal end and the distal end and an induction coil operably coupled to the stimulus delivery mechanism. Further, the device may include an external controller wirelessly coupled to the induction coil for inductively transferring energy to the induction coil. 130- (canceled)31. A device for inducing production of tears , comprising:a body extending from a proximal end to a distal end, wherein the body is comprised of a braid or mesh and is configured for insertion through a punctum of a subject;a stimulus delivery mechanism positioned between the proximal end and the distal end; anda faceplate adjacent the proximal end of the body;wherein the faceplate abuts, and is located external to, the punctum when the body is inserted through the punctum.32. The device of claim 31 , wherein the braid or mesh is comprised of one or more biocompatible materials.33. The device of claim 32 , wherein the one or more biocompatible materials is Nitinol or a polymer.34. The device of claim 31 , wherein the faceplate includes a power receptor at least partially disposed therein or thereon.35. The device of claim 31 , wherein the mesh is self-expanding.36. The device of claim 35 , wherein the mesh self-expands into conformity with a portion of a nasolacrimal drainage system of the subject after insertion of the body through the punctum.37. The device of claim 31 , wherein the mesh is not self-expanding.38. The device of claim 31 , wherein separate portions of the mesh are conductive so that delivery of a stimulation signal to the stimulus delivery device causes stimulation to be delivered through the separate portions of the mesh to a tissue of a nasolacrimal drainage system of the subject.39. The device of claim 38 , wherein ...

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Номер записи: 56
08-02-2018 дата публикации

Device and Methods For Use In Removal Of Bio-Film And Treatment Of Halitosis

Номер: US20180036554A1
Автор: Krespi Yosef
Принадлежит:

A device for removal of bio-film without cutting or injury to tissue is provided which is an elongated, thin and flexible member which encases a fiber optic piece and having a downward curved section at or near one end. The fiber optic protrudes from the end of the member and is covered by a diffuser to create a light emitting head, which can be used to direct light energy to a selected treatment site. Disclosed are safe, simple and effective broad-spectrum treatments for bio-film removal, such as halitosis and other microbial infections of the non-dental upper respiratory tract useful to treat bacterial and other microorganism species, including anaerobic bacteria. Electromagnetic radiative energy including visible, and optionally, thermal, RF and/or microwave wavelengths, is topically applied to internal surfaces of the upper respiratory tract to destroy or incapacitate superficial microorganisms without the use of antibiotics. 1. A device for removal of bio-film without cutting or injury to tissue comprising:an elongated and flexible member having a first end and a second end with a downward curved section approaching the second end;the first end of said elongated piece connected and inserted into to a fastener attachment at a first end of the fastener attachment;said fastener attachment having a second end for connection to a handle grip and receiving an energy supply;said elongated flexible member is a hollow sheath encasing a fiber optic piece for the length of the elongated flexible member;a fiber optic tip of said fiber optic piece protruding from the second end of the elongated member from which the treatment light energy emits;said fiber optic tip enclosed in a hollow diffuser piece fastened onto the second end of the elongated flexible member to form a light output head of the device;said diffuser piece allows light energy to emit from an open bottom of the diffuser piece and delivers visible light energy to non-dental target tissue site;said non-dental ...

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Номер записи: 57
24-02-2022 дата публикации

DENTAL LASING DEVICE SYSTEM AND METHOD

Номер: US20220054226A1
Автор: Gregg, Gregg Austen R.H., Gregg Dawn M., II Robert H.
Принадлежит:

A diode laser system having high-power diode(s) said high-power diode(s) producing laser outputs in a range of 0.1 to 25 Watts of power using optimum wavelengths via a single optical delivery fiber. 1. A diode lasing method for dental oral surgery comprising the steps of:providing only three laser diodes, a first of the three laser diodes is a blue laser with a wavelength 400 to 510 nanometers, a second of the three laser diodes is an infrared laser with a wavelength of 800-1200 nanometers, and a third of the three laser diodes is a red laser with a wavelength of 600-750 nanometers;installing the laser diodes in a laser diode module;installing the laser diode module, a power meter, an internal reference, and a digital controller in a laser console having a display and user input interface;controlling the laser diodes via the digital controller, the first laser diode for operation at 10-20 Hz with a pulse width of 20-100 ms and a power of up to 5 watts, the second laser diode for operation 10-50 Hz with a pulse width of 20-100 ms and a power of up to 25 Watts, the third laser diode for operation continuously with a power of up to 1000 mW;cooling the laser diode module with a Peltier cell thermoelectric cooler controlled by a temperature sensor, the Peltier cell between the laser diode module and a heat sink for dissipating the heat lost from the laser module;combining up to three light beams from the three laser diodes in an optical stage including a transformation lens, a dispersion element, and an external cavity mirror wherein the three light beams impinge on the transformation lens where the light beams are focused to a single point on the dispersion element such that a single beam leaves the dispersion element, impinges on the external cavity mirror;transporting a reflection of the single beam in a single optical fiber with a core diameter of about 360 μm and a numerical aperture of 0.22 to 0.34, proper optical interface(s) being checked with one or more SMA ...

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Номер записи: 58
07-02-2019 дата публикации

At-Home Light-Emitting Diode and Massage Device for Vaginal Rejuvenation

Номер: US20190038501A1
Автор: Andersen Roger, Bailey Kevin, Bailey Matthew, Courtion Colette, Klimava Yana, Loebel Nicolas
Принадлежит:

A light emitting module and massage device provide vaginal rejuvenation. The device exposes collagen in the vaginal area or mucosa to temperatures elevated over normal body temperature to cause the collagen to reversibly or irreversibly denature while simultaneously applying vibration. Once thermally-induced collagen denaturation has occurred, both neoelastogenesis and neocollagenesis may occur and may be initiated with fibroblast proliferation, which may be promoted with vibration. Neofibrogenesis also occurs due to the fibroblastic activity, responsible for secretion of new collagen matrix to effect tissue repair. Thus, the device exploits thermally-induced collagen denaturation and repair along with simultaneous vibration to improve tissue tone, connective tissue tension and bulk tissue regeneration. 1. A rejuvenation device comprising: a shell forming an external surface of the insertable section that is adapted to contact vaginal tissue, the shell comprising a treatment band formed around a circumference of the shell and designed to allow passage of light through the treatment band,', 'a component enclosed within the treatment band, the component extending length-wise along the treatment band, and', 'one or more light emitters arranged around the component;, 'an insertable section that is insertable into a vagina, the insertable section comprisinga vibration mechanism configured to provide vibration to the vaginal tissue; anda controller configured to communicate with the one or more light emitters and the vibration mechanism to control delivery of light and vibration to the vaginal tissue.2. The rejuvenation device of claim 1 , wherein the shell of the insertable section further comprises at least one of the following: a first portion forming a rounded end of the insertable section that is distal to the treatment band and a second portion formed around the circumference of the shell and located proximal to the treatment band.3. The rejuvenation device of claim ...

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Номер записи: 59
18-02-2016 дата публикации

Irradiation device

Номер: US20160045757A1
Автор: Morten Groseth
Принадлежит: PHOTOCURE ASA

An irradiation device for insertion into an orifice of the body to provide photodynamic therapy comprises: a housing moulded from a resilient material and adapted to be fully inserted and secured in the orifice, the housing enclosing an LED lamp system 22 and a power source 41 for powering the LED lamp system 22 ; wherein the device is independently operational while located in the orifice; characterised in that: the housing comprises a first housing part 2 for holding the power source 41 and a second housing part 4 for holding the LED lamp system 22 , the first and second housing parts 2, 4 being separable and being preferably formed separately from the LED lamp system 22 ; and in that the first housing part 2 consists of a chamber 6 for holding the power source 41 and an opening 26 into the chamber 6 is provided through a resilient opening part 8 , wherein the chamber 6 is closed when the first housing part 2 is joined to the second housing part 4.

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Номер записи: 60
15-02-2018 дата публикации

Sexual stimulation device using light therapy, vibration and physiological feedback

Номер: US20180042809A1
Автор: Ralph Zipper
Принадлежит: Individual

A sexual stimulation apparatus and method which may comprise a plurality of light sources for photostimulation of the vagina, clitoris, or both; one or more vibrators for mechanical stimulation of an area of the vagina; a handle; a controller and programmable memory for containing non-transitory instructions for modes of operation and driving the light sources and vibrators of the invention; a vaginal finger; a handle for ease of use; a keypad for user entry of commands; and a charging or programming port. The invention may also comprise sensors that sense physiologic parameters of a user and adjust sexual stimulation parameters to achieve a desired sexual stimulation effect. Blood oxygen level, temperature, pulse rate and muscle electrical activity may be sensed. The invention also may comprise a flexible covering that provides smooth sliding engagement with an area of the vagina of a user.

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Номер записи: 61
03-03-2022 дата публикации

Apparatus and method for irradiating inside an object

Номер: US20220062654A1
Автор: Leonid VESSELOV, Roger J. Dumoulin-White
Принадлежит: Theralase Technologies Inc

An apparatus for irradiating inside an object is disclosed, including a lumen having a longitudinal axis; optical fibers within the lumen and aligned with the longitudinal axis; and an illumination member moveable or fixed within the lumen along the longitudinal axis. The apparatus can be used in a method for irradiating inside an object, including the steps of: providing an object having a cavity defined by an internal surface; inserting the lumen into the cavity; activating the illumination member to irradiate the internal surface with emitted light; receiving in each of the optical fibers light redirected from the internal surface; conveying the redirected light in a proximal direction through the plurality of optical fibers; and analyzing the redirected light conveyed through the plurality of optical fibers.

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Номер записи: 62
13-02-2020 дата публикации

Ultrasonic Phototherapeutic Dental Braces And Use Method

Номер: US20200046476A1
Автор: Dong Xiaoxi, Li Yingxin, Zou Zhaohui
Принадлежит: Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Biomedical Engineer

The present invention discloses ultrasonic phototherapeutic dental braces and a use method. The dental braces include: a transparent substrate, a phototherapeutic optical fiber, an ultrasonic transducer, an incoming line slot, a wire, and a plastic keel, where the phototherapeutic optical fiber, the ultrasonic transducer, the wire, and the plastic keel are all disposed inside the transparent substrate; the transparent substrate includes an arched end and a performed slot; the performed slot is used for fastening the transparent substrate on teeth of a person; the incoming line slot is disposed at the arched end of the transparent substrate; the incoming line slot is used for leading the wire and the phototherapeutic optical fiber into the transparent substrate; the phototherapeutic optical fiber is used for emitting therapy light to irradiate the therapy light into the oral cavity; the wire is connected to the ultrasonic transducer, the wire is externally connected to a power supply, and is used for supplying power for the ultrasonic transducer; the ultrasonic transducer is used for emitting ultrasonic waves; and the plastic keel is used for adjusting a shape of the transparent substrate. The present invention harmonically combines mechanically cleaning the oral cavity with ultrasonic waves with a photobiomodulation on the oral cavity, and can better protect the oral cavity environment of a user. 1. Ultrasonic phototherapeutic dental braces , comprising: a transparent substrate , a phototherapeutic optical fiber , an ultrasonic transducer , an incoming line slot , a wire , and a plastic keel , wherein the phototherapeutic optical fiber , the ultrasonic transducer , the wire , and the plastic keel are all disposed inside the transparent substrate; the transparent substrate comprises an arched end and a performed slot; the performed slot is used for fastening the transparent substrate on teeth of a person; the incoming line slot is disposed at the arched end of the ...

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Номер записи: 63
25-02-2021 дата публикации

OPTICAL THERAPEUTIC APPARATUS AND OPTICAL THERAPEUTIC METHOD

Номер: US20210052914A1
Автор: YOSHINO MASAHIRO
Принадлежит: OLYMPUS CORPORATION

An optical therapeutic apparatus includes: a liquid discharge catheter including a first tubular member; a balloon catheter including a shaft, a balloon and a second tubular member; and a light irradiation body. The balloon is positioned such that the balloon is exposed from a distal end of the liquid discharge catheter by bringing the second tubular member into contact with the first tubular member. 1. An optical therapeutic apparatus comprising:a liquid discharge catheter including a lumen for liquid discharge, and a first tubular member with which a proximal end of the lumen for liquid discharge communicates;a balloon catheter including a second tubular member provided with a shaft which includes one end and another end and is insertable into and removable from the lumen for liquid discharge of the liquid discharge catheter, a balloon mounted on the one end of the shaft, and a port disposed on the other end of the shaft and through which a liquid for inflating the balloon can be injected, the balloon catheter including a lumen for injection which makes the port and the balloon communicate with the shaft; anda light irradiation body configured to emit light having a preliminarily set wavelength from a diffuse functional unit of a probe distal end in a state where the light irradiation body is inserted into the lumen for injection mounted on the shaft of the balloon catheter, the probe distal end is positioned in the balloon, and the liquid is injected into the balloon, whereinthe balloon is positioned to be exposed from a distal end of the liquid discharge catheter by bringing the second tubular member into contact with the first tubular member.2. The optical therapeutic apparatus according to claim 1 , wherein an effective length of the balloon catheter is greater than an effective length of the liquid discharge catheter.3. The optical therapeutic apparatus according to claim 2 , wherein the liquid discharge catheter includes a through hole through which the ...

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Номер записи: 64
23-02-2017 дата публикации

NASOLACRIMAL IMPLANTS AND RELATED METHODS FOR TEAR STIMULATION

Номер: US20170049619A1
Автор: Kahook Malik Y.
Принадлежит: The Regents of the University of Colorado, a body corporate

A device for inducing production of tears may include a body extending from a proximal end to a distal end. The body may be configured for insertion through a puncta of a subject. The device also may include a stimulus delivery mechanism positioned between the proximal end and the distal end and an induction coil operably coupled to the stimulus delivery mechanism. Further, the device may include an external controller wirelessly coupled to the induction coil for inductively transferring energy to the induction coil. 1. A device for inducing production of tears , comprising:a body extending from a proximal end to a distal end, wherein the body is configured for insertion through a puncta of a subject; anda stimulus delivery mechanism positioned between the proximal end and the distal end.2. The device of claim 1 , wherein the stimulus delivery mechanism includes a conductor.3. The device of claim 2 , further including a plurality of conductors positioned between the proximal end and the distal end of the body.4. The device of claim 1 , wherein an induction coil is operably coupled to the stimulus delivery mechanism.5. The device of claim 1 , wherein the body is configured for direct contact with a portion of a nasolacrimal drainage system of a subject.6. The device of claim 1 , further including a faceplate adjacent the proximal end of the body.7. The device of claim 1 , further including a sensor configured for sensing one or more of biochemical properties of tears claim 1 , placement of the body claim 1 , and operation of the stimulus delivery mechanism.8. A device for inducing production of tears claim 1 , comprising:a body extending from a proximal end to a distal end, wherein the body is configured for insertion within a portion of a nasolacrimal drainage system of a subject;a stimulus delivery mechanism positioned between the proximal end and the distal end;a power receptor operably coupled to the stimulus delivery mechanism; andan external controller coupled ...

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Номер записи: 65
08-05-2014 дата публикации

IMPLANTABLE CLIPT ILLUMINATION SYSTEM

Номер: US20140128943A1
Автор: Hill Samuel L., Rogers Gary S.
Принадлежит: Rogers Sciences, Inc.

A light-based therapy device is provided that includes a controller mechanism that produces power and control signals to enable operation of one or more medical devices. An implantable light delivery device (IM-LDD) is coupled to the controller mechanism that receives the power and the control signals to enable a light source to emit sufficient illumination. The light source is implanted within body cavities enabling energy at one or more wavelengths to reach and provide therapy treatment to a selected region. 1. An implantable light delivery device (IM-LDD) comprising a light source that can emit sufficient illumination and be implanted within body cavities or luminal surfaces enabling energy at one or more wavelengths to reach and provide therapy treatment at selected region.2. The IM-LDD of claim 1 , wherein the body cavities or luminal surfaces comprise esophagus claim 1 , upper and lower GI tract claim 1 , genito-urinary tract claim 1 , bladder claim 1 , pelvis claim 1 , peritoneum claim 1 , pulmonary cavity claim 1 , hepatobilliary tree claim 1 , bronchial tree claim 1 , blood vessels or calvarium/CNS.3. The IM-LDD of claim 1 , wherein the light source provides repeated claim 1 , continuous or recurrent light delivery.4. The IM-LDD of claim 1 , wherein the light source comprises etched fibers.5. The IM-LDD of claim 4 , wherein the light source comprises an optical element array delivering the required therapeutic doses.6. The IM-LDD of claim 5 , wherein the therapeutic doses comprise NIR energy for PEG-NR activation.7. The IM-LDD of claim 1 , wherein light source comprises fibers rolled into a circular stent.8. The IM-LDD of claim 1 , wherein the light source comprises a pad structure coupled to optical fibers to be implanted.9. The IM-LDD of claim 1 , wherein the light source comprises an internal RF-coil and an internal control mechanism being powered via an external system.10. The IM-LDD of claim 9 , wherein the external system comprises a wearable ...

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Номер записи: 66
10-03-2022 дата публикации

Light-Emitting Diode and Massage Device for Delivering Focused Light for Vaginal Rejuvenation

Номер: US20220071838A1
Автор: Andersen Roger, Bailey Kevin, Bailey Matthew, Courtion Colette, Klimava Yana, Loebel Nicolas
Принадлежит:

A rejuvenation and massage device is provided for treating mucosa tissue, such as vaginal tissue, affected by Vaginal Relaxation Syndrome (VRS) or other conditions, through vibration, thermal loading, and light emittance for a duration of time. In one embodiment, the device is an insertable device that includes Low-Level Laser Light (LLLT) therapy to treat the vaginal tissue. The light emittance by one or more light emitters is in a range sufficient to provide therapeutic effects through light radiation. To enhance the therapeutic effects of light radiation provided by the device, the device is configured to provide increased energy density into target tissue of vaginal muscles though a light configuration component (e.g., a focusing component, such as a concave lens assembly, a convex assembly, a pre-lensed light emitter or other focusing optical mechanism) associated with the light emitter that concentrates the light emitted from the light emitter. 1. A device for tissue rejuvenation therapy , the device comprising:{'claim-text': ['a first shell portion forming an external surface of the insertable body and composed of a silicone material, and', 'a second shell portion within the first shell portion; and'], '#text': 'an insertable body that is insertable into a cavity, the insertable body comprising:'}{'claim-text': ['a set of light emitters radially distributed about a longitudinal axis within the within the insertable body, and', 'a set of focusing components that focus light emitted from the set of light emitters onto a mucosa tissue within the cavity, during operation, to provide adjustment of light transmission to the mucosa tissue within the cavity.'], '#text': 'a light emitting subsystem within the insertable body, the light emitting subsystem comprising:'}2. The device of claim 1 , further comprising a safety temperature component comprising a thermocouple assembly in thermal communication with the mucosa tissue claim 1 , through at least one of the first ...

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Номер записи: 67
03-03-2016 дата публикации

LED BASED VAGINAL LIGHT THERAPY DEVICE

Номер: US20160059034A1
Автор: Klang Gregg Alan
Принадлежит:

The embodiments herein provide an LED based vaginal light therapy device for a plurality of bacterial and fungal infections. The device comprises an LED body, a cervix support, a single or a plurality of LEDs, a switch, a tether, microchip and a battery. One end of the device comprises a cervix support to place the device smoothly against the cervix. A plurality of LEDs is provided over the LED body. The LED body comprises one or more LEDs and each LED emits a light having a wavelength in a therapeutic zone of light. The light emitted are in a range of blue light and/or red light. The microchip is housed within the LED body. The microchip connects a battery to the single or plurality of LED's and is further connected to the switch. 1. An LED based vaginal light therapy device for a plurality of bacterial and fungal infections comprises:an LED body, wherein the LED body is made up of a hardened material;a cervix support, wherein the cervix support is provided at an end of the LED body to place the device smoothly against a vaginal cervix;one or more LEDs, wherein the one or more LEDs is present on the LED body, wherein each LED emits a light having a wavelength in a range of non-UV germicidal light;a switch, wherein the switch is a pressure activated switch present on the LED body;a microchip, wherein the microchip is housed within the LED body, wherein the microchip connects a battery to the one or more LEDs, wherein the microchip is further connected to the switch;a tether, wherein the tether is connected with the LED body and is used for retreating and/or progressing the device through a vagina of a patient;wherein, the switch and the one or more LEDs draw a power from the battery through the microchip, wherein the switch controls an activation as well as deactivation of the one or more LEDs on the basis of a pressure sensing by the intravaginal walls.2. The device according to claim 1 , wherein the non-UV germicidal light comprises a range of blue light with 405 ...

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Номер записи: 68
03-03-2016 дата публикации

Method of Reducing the Occurrence of Arrhythmias Via Photobiomodulation and Apparatus for Same

Номер: US20160059035A1
Автор: Bjorling Anders, Emmanuelsson Cecilia, Jarverud Karin, Noren Kjell
Принадлежит:

In response to local or systemic inflammation in a patient, photobiomodulation therapy is applied to a cardiac location to reduce the risk and/or occurrence of cardiac arrhythmia. Once inflammation is identified, photobiomodulation therapy can be applied in any suitable fashion (e.g., via a catheter- or transesophageal probe-mounted photoemitter, via an externally-applied photoemitter, or via photoemitter incorporated into an implantable medical device). Photobiomodulation therapy can also be employed to good advantage in conjunction with non-photobiomodulation therapy (e.g., traditional cardiac rhythm management therapies). 115-. (canceled)16. A medical device for implantation into a cardiac tissue in order to reduce occurrence of cardiac arrhythmias comprising:a photoemitter configured to deliver photobiomodulation therapy to the cardiac tissue; andat least one of a sensor to monitor a physiologic characteristic and a therapy delivery element to deliver a non-photobiomodulation therapy to the cardiac tissue.17. The medical device according to claim 16 , wherein the sensor to monitor a physiologic characteristic comprises a pressure sensor.18. The medical device according to claim 16 , wherein the sensor to monitor a physiologic characteristic comprises an accelerometer.19. The medical device according to claim 16 , wherein the photoemitter comprises an optical fiber coupled to a light source.20. The implant according to claim 16 , wherein the photoemitter comprises a litroenergic material.21. The implant according to claim 16 , wherein the sensor to monitor a physiologic characteristic comprises a motion sensor.22. The implant according to claim 16 , wherein the sensor to monitor a physiologic characteristic comprises a sensor for measuring cardiac electrograms.23. The implant according to claim 16 , further comprising a control system claim 16 , and wherein the control system is configured:to receive an input from the sensor;to detect, from the input, a ...

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Номер записи: 69
20-02-2020 дата публикации

A METHOD FOR STIMULATING RETINAL CELLS AND TREATING VISION LOSS

Номер: US20200054441A1
Автор: Birge Robert R, Greco Jordan A, Wagner Nicole
Принадлежит:

Protein-based subretinal implants offer a new approach to restoring vision for patients blinded by conditions such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP). The present invention relates to bacteriorhodopsin-based (BR-based) retinal implants that can be implanted in a subretinal position to replace degenerated photoreceptor cells. 1. A method for treating a patient having loss of vision caused by loss of retinal cells , comprising ,(a) implanting into an eye of the patient a bacteriorhodopsin-based retinal implant, and(b) activating the implant with a light source,wherein the implant stimulates retinal cells such that the stimulation is provided at a resolution with pixel dimensions less than about 500 μm, or less than about 350 μm, or less than about 250 μm, or less than about 200 μm, or less than about 150 μm, or less than about 100 μm, or less than about 75 μm, or less than about 50 μm, or less than about 40 μm, or less than about 30 μm, or less than about 25 μm.2. A method for treating a patient having loss of vision caused by loss of retinal cells , comprising ,(a) implanting into an eye of the patient a bacteriorhodopsin-based retinal implant, and(b) activating the implant with a light source,wherein the implant stimulates retinal cells such that the stimulation is provided at a resolution limited by (i) the diffraction limit of the light source or (ii) when the retinal implant further comprises an ion-permeable substrate, the aperture diameter and density of the ion-permeable substrate.3. A method for treating a patient having loss of vision caused by loss of retinal cells , comprising ,(a) implanting into an eye of the patient a bacteriorhodopsin-based retinal implant, and(b) activating the implant with a light source,{'sup': 2', '2', '2', '2', '2', '2', '2', '2', '2', '2', '2, 'wherein the implant stimulates retinal cells such that the stimulation is provided at a resolution with a pixel density of about 4 pixels/mmand pixel ...

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Номер записи: 70
20-02-2020 дата публикации

RHINITIS PHOTO THERAPEUTIC DEVICE WITH A NASAL PROBE USING LOW-LEVEL LASER BASED ON DIFFUSING LIGHT TECHNOLOGY

Номер: US20200054891A1
Автор: PARK Bae Keun
Принадлежит:

There is disclosed a rhinitis photo therapeutic device with a nasal probe using a low-level laser based on diffusing light technology. In the rhinitis photo therapeutic device with a nasal probe using a low-level laser based on diffusing light technology of the invention, the probe has a configuration in which a light source using a low-level laser is installed, and laser light emitted from the light source is diffused through a lens, and the light is guided through a total reflection prism. In this manner, the rhinitis photo therapeutic device has an effect of relieving inflammation and pain in a nasal cavity by using low-level laser therapy (LLLT). 1. A rhinitis photo therapeutic device with a nasal probe using a low-level laser based on diffusing light technology ,wherein the probe has a configuration in which a light source using a low-level laser is installed, and laser light emitted from the light source is diffused through a lens, and the light is guided through a total reflection prism.2. The rhinitis photo therapeutic device with a nasal probe using a low-level laser based on diffusing light technology according to claim 1 ,wherein the probe includesa pair of laser diode covers that each has a inner surface provided with multiple semicircular recesses for inducing light diffusion with a transparent structure,a lens that is inserted in each of the laser diode covers and diffuses light emitted from a laser diode,a pair of nose clamps that presses a columella nasi,a probe cover in which the pair of laser diode covers is inserted, and the pair of nose clamps is inserted between the laser diode covers,an inner cover which is joined to a lower portion of the probe cover so as to support the nose clamps and in which the laser diode is inserted, anda lower cover that is joined to the probe cover.3. The rhinitis photo therapeutic device with a nasal probe using a low-level laser based on diffusing light technology according to claim 2 ,wherein each of the nose ...

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Номер записи: 71
17-03-2022 дата публикации

ELECTRICAL DISCHARGE IRRIGATOR APPARATUS AND METHOD

Номер: US20220079732A1
Автор: Avniel Yuval Charles, Fregoso Gilbert, Heckerman Brad, Meuchel Dennis
Принадлежит:

An electrical discharge irrigation device and method is described. An electrical discharge irrigation device includes a power source, a circuit coupled to the power source, and an output tip coupled to the circuit. The output tip includes a first end and a second end and a longitudinal axis extending between them, an electrode located in an interior space of the output tip configured to receive an electrical charge from the circuit and to release an electric discharge, and a ground return including an inner surface of the output tip, wherein a space between the electrode and the ground return comprises a conductive medium, the conductive medium being in contact with the electrode and the ground return to produce the electric discharge. 1. An electrical discharge irrigation device , comprising:a power source;a circuit coupled to the power source; and a first end and a second end and a longitudinal axis extending between them;', 'an electrode located in an interior space of the output tip configured to receive an electrical charge from the circuit and to release an electric discharge; and', 'a ground return comprising an inside surface of the output tip, wherein a space between the electrode and the ground return comprises a conductive medium, the conductive medium being in contact with the electrode and the ground return to produce the electric discharge., 'an output tip coupled to the circuit, the output tip comprising2. The device of claim 1 , further comprising at least one opening on an outside surface of the output tip claim 1 , wherein the electrical discharge creates cavitation within the conductive medium.3. The device of claim 2 , wherein sonoluminescence occurs responsive to the cavitation and wherein light is visible to an operator of the device during operation of the device.4. The device of claims 1 , wherein the conductive medium exits the output tip through the at least one opening in the tip.5. The device of claim 2 , wherein the output tip can be ...

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Номер записи: 72
22-05-2014 дата публикации

LASER ASSISTED PERIODONTIUM AND OSSEUS REGENERATION PROTOCOL

Номер: US20140141389A1
Автор: Kalmeta Margaret V.
Принадлежит:

A method of treating gum disease using a soft tissue diode laser which generates a beam of light having a wavelength in the visible portion of the electromagnetic spectrum (400 nm-700 nm) at a laser power of 0.5 to 1.2 watts, used with intermittent stops to control tissue temperature, to decontaminate the gum tissue and biostimulate the periodontium nonsurgically when used with a substrate, thus preventing the long junctional epithelium from migrating into the sulcus, preserving tissue height, and regenerating periodontium, the method comprising: placing the tip of the laser inside the sulcus; penetrating the entire sulcus by moving the laser light with intermittent stops to control tissue temperature vertically and horizontally throughout the sulcus; and placing a substrate in the sulcus prior to a blood clot forming, thus regenerating periodontium in the sulcus. 1. A substrate mixture for the treatment of gum disease , wherein the substrate mixtures is comprised of:a) a first substrate; andb) a second substrate.2. The substrate mixture of claim 1 , wherein the first substrate is comprised of:a) 60% sterile waterb) 1.1% sodium chloride;c) 1% benzoic acid;d) 9% Lysine;e) 9% Proline;f) 9% essential amino acids, wherein the essential amino acids include equal parts Isoleucine, Leucine, Methionine, Phenylalanine, Threonine, Tryptophan, Valine and Histadine;g) 2% non-essential amino acids, wherein the non-essential amino acids include equal parts Alanine, Arginine, Aspartate, Glutamate, Glycine and Serine;h) 2% phosphates, wherein the phosphates include equal parts adenosine diphospate (ADP), adenosine triphosphate (ATP), and Acetylcholine; andi) 6.9% free bases, wherein the free bases include equal parts adenosine, uridine, guanosine, and cytidine.3. The substrate mixture of claim 1 , wherein the second substrate is comprised of:a) tricalcium phosphate, wherein the tricalcium phosphate is precipitated in calcium hydroxide and Claw oil; andb) hydroxyapatite crystals.5. ...

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Номер записи: 73
10-03-2016 дата публикации

PHOTO-CHEMICALLY ACTIVATED MICRO-BUBBLE BASED ROOT CANAL DISINFECTION

Номер: US20160067149A1
Автор: KISHEN Anil
Принадлежит:

A photo-chemically activated micro-bubble based root canal disinfection method for disinfecting a shaped root canal comprises (a) introducing a photoactive solution into the root canal, the photoactive solution containing a photoactive compound (such as methylene blue) dissolved in an alcohol carrier solution (such as polyethylene glycol and/or ethanol); (b) removing excess photoactive solution from the root canal; (c) introducing a micro-bubble solution comprised of an oxygen carrier (such as perfluorocarbon), an oxidizing agent (such as hydrogen peroxide) and a surfactant (such as a nonionic polyoxyethylene surfactant); (d) sonically or ultrasonically activating the micro-bubble solution in the canal; and (e) introducing light into the canal. 1. A method of disinfecting a shaped root canal comprising:a) introducing a photoactive solution into the root canal, the photoactive solution containing a photoactive compound dissolved in an alcohol carrier solution;b) removing excess photoactive solution from the root canal;c) introducing a micro-bubble solution comprised of an oxygen carrier, an oxidizing agent and a surfactant;d) sonically or ultrasonically activating the micro-bubble solution in the canal; ande) introducing light into the canal.2. The method according to wherein step (d) and (e) are performed simultaneously.3. The method according to wherein the step of introducing the photoactive solution into the root canal comprises flushing the root canal with the photoactive solution.4. The method according to wherein the step of removing excess photoactive solution is performed after the root canal has been exposed to the photoactive solution for at least about 60 seconds.5. The method according to wherein the step of removing excess photoactive solution is performed after the root canal has been exposed to the photosensitive solution for about 60 seconds to about 180 seconds.6. The method according to wherein the micro-bubble solution is mechanically activated in ...

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Номер записи: 74
29-05-2014 дата публикации

Device for Dentistry Treatments

Номер: US20140147802A1
Автор: Naldoni Moreno
Принадлежит: GP INVESTIMENTI S.r.l.

Device for dentistry treatments having a photodiagnosis unit for performing photodiagnosis of a portion of gingival tissue, a temperature measurement unit for measuring the temperature of the portion of gingival tissue, a photoablation unit for performing photoablation of part of the portion of gingival tissue, a phototherapy unit for performing photodynamic and/or photoinductive therapy of the portion of gingival tissue, a control unit configured to acquire, by means of the photodiagnosis unit and the temperature measurement unit, information relative to the state of the portion of gingival tissue, and to control operation of the photoablation and phototherapy units according to the information acquired. 1253462534. A device for dentistry treatments , comprising at least one photodiagnosis unit () for performing a photodiagnosis of at least one portion of gum tissue , at least one temperature measurement unit () for measuring the temperature of said portion of gum tissue , at least one photoablation unit () for performing a photoablation of at least part of said portion of the gum tissue , at least one phototherapy unit () for performing a photodynamic therapy and/or a photoinductive therapy of said portion of the gum tissue , processing and control means () configured to acquire , by means of said photodiagnosis unit () and said temperature measurement unit () , information concerning the state of the portion of gum tissue and to control the operation of the photoablation and phototherapy units ( , ) as a function of said information.22273027. A device according to claim 1 , wherein said photodiagnosis unit () comprises a first optical source () for emitting optical radiations having a first wave length (L2) selected within the interval ranging from 350 to 450 nm and optical receiver means () for detecting optical radiations which claim 1 , in use claim 1 , are reflected claim 1 , or emitted by fluorescence claim 1 , by said portion of gum tissue claim 1 , when ...

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Номер записи: 75
29-05-2014 дата публикации

NON-SURGICAL METHOD FOR TIGHTENING BOTH EXTERNAL PUBIC AND INTERNAL VAGINAL TISSUES IN A SINGLE PROCEDURE

Номер: US20140148878A1
Автор: Khatri Khalilullah A.
Принадлежит:

A non-surgical method for improving both the external pubic appearance and the internal vaginal tightness of a female patient in a single procedure includes providing a cosmetic skin-tightening device having a wand having a tip that applies heating energy to skin collagen, where the wand is shaped such that the tip can be inserted into the patient's vagina. During the procedure, the wand is alternately passed over the external pubic skin and inserted into the patient's vagina, thereby tightening both the pubic and vaginal regions during a single procedure while preventing overheating of any one area. The heat energy can be conductively transmitted heat or a radiated energy such as infra-red, laser, or radio frequency energy. A disposable sleeve can be applied over the wand to facilitate cleaning and sterilization after use. A vaginal lubricant and/or ultrasound gel can be applied. 1. A method applicable to a female patient for tightening tissue in both the external pubic area and the internal vaginal area during a single treatment session using a single device , the method comprising:providing a cosmetic device that is able to emit energy from a wand that heats collagen in skin, the wand having an energy-emitting tip proximal to a distal end of an elongated extension, the elongated extension and the energy-emitting tip having sizes and shapes that enable the energy-emitting tip to be inserted within the patient's vagina and to be located at substantially any depth within the vagina;locating the energy-emitting tip adjacent to external skin in the patient's pubic area, thereby heating and tightening the external skin; andinserting the energy-emitting tip into the patient's vagina, thereby heating and shrinking tissue within the vagina.2. The method of claim 1 , wherein the wand is connected to the cosmetic device by an umbilical cable.3. The method of claim 1 , wherein the skin-heating energy is laser energy.4. The method of claim 1 , wherein the skin-heating energy ...

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Номер записи: 76
15-03-2018 дата публикации

PHOTOTHERAPY DEVICES AND METHODS

Номер: US20180071066A1
Автор: Hébert Lise, Loupis Nikolaos, Piergallini Remigio
Принадлежит:

The present disclosure relates to a phototherapy device that can deliver light to tissues to activate photoactive agents that have been applied to the tissues or that are included within a fiber optic tip member of the device which may be coupled to a light source using a sleeve. The present disclosure also relates to methods of phototherapy using the phototherapy device such as anti-bactericidal treatment, anti-fungal treatment, anti-parasitic treatment, anti-viral treatment. 139-. (canceled)40. A method for treating periodontal disease , comprising:attaching to a light source having one or more light emitting diodes a periodontal probe member, the probe member having a flexible fiber optic tip member with a polymer or glass core for transmitting light, and an elastic tubular connector sleeve, for mechanically coupling the flexible tip member to a light source;introducing a composition comprising a photoactivating agent and oxygen-releasing agent into a periodontal treatment region;introducing the flexible tip member in the periodontal treatment region; andactivating the photoactivating agent by applying light through the flexible fiber optic tip member to the periodontal treatment region.4146-. (canceled)47. A method for treating wounds , comprising:attaching to a light source having one or more light emitting diodes a wound probe member, the wound probe member having a flexible fiber optic tip member with a polymer or glass core for transmitting light, and an elastic tubular connector sleeve, for mechanically coupling the flexible tip member to a light source; 'introducing the flexible tip member in the treatment region; and', 'introducing a composition comprising a photoactivating agent and oxygen-releasing agent into a treatment region;'}activating the photoactivating agent by applying light through the flexible fiber optic tip member to the treatment region.48. A method for phototherapy , comprising:attaching to a light source a probe member, the probe member ...

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Номер записи: 77
24-03-2022 дата публикации

SURGICAL SITE DISINFECTION DEVICES

Номер: US20220088409A1
Автор: Dombrowski Joseph, GRESZLER Alan, Kerns Michael, Thotagamuwa Dinusha
Принадлежит:

A surgical site disinfection device is provided for disinfecting a surgical site. The surgical site disinfection device directs electromagnetic radiation having germicidal properties into the surgical site using a light guide. 1. A surgical site disinfection device for disinfecting a surgical site using electromagnetic radiation from a light source having germicidal properties , the surgical site disinfection device comprising:{'claim-text': ['receive the electromagnetic radiation emitted by the light source at a distal end of the light guide;', 'transmit the received electromagnetic radiation from the distal end to a light emitting end of the light guide; and', 'emit the transmitted electromagnetic radiation from the light emitting end of the light guide;'], '#text': 'a light guide configured to:'}a housing configured to mechanically support a supported portion of the light guide, such that the electromagnetic radiation emitted from the light emitting end is directed towards the surgical site.2. The surgical site disinfection device of claim 1 , wherein the housing includes a surgical retractor.3. The surgical site disinfection device of claim 1 , wherein the light guide comprises a tube having a lumen bound by an inner surface that is reflective to the electromagnetic radiation claim 1 , such that the electromagnetic radiation received at the distal end of the light guide is directed towards the light emitting end via reflection by the inner surface.4. The surgical site disinfection device of claim 3 , wherein the inner surface is reflective to the electromagnetic radiation due to the inner surface being coated with a reflective material.5. The surgical site disinfection device of claim 4 , wherein the reflective material includes aluminum.6. The surgical site disinfection device of claim 3 , wherein the tube is hollow.7. The surgical site disinfection device of claim 3 , wherein the tube of the light guide is made from plastic.8. The surgical site disinfection ...

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Номер записи: 78
16-03-2017 дата публикации

IRRADIATION DEVICE

Номер: US20170072217A1
Автор: Groseth Morten, Klem Bjorn
Принадлежит:

An irradiation device for insertion into an orifice of the body for providing photodynamic therapy or diagnosis comprises: a housing adapted to be fully inserted and secured in the orifice, the housing enclosing an LED lamp system and a power source , for powering the LED lamp system , wherein the device is independently operational while located within the orifice. 1. An irradiation device for insertion into a vagina of a human for providing photodynamic therapy to a cervix of a human , the device having a front end and a rear end , the rear end being the part of the device which , in use , is closest to the entrance of the vagina , wherein the device is adapted to be fully inserted and secured in the vagina , the device comprising a flexible housing comprising:(a) a treatment surface which is, in use, placed against the cervix, said treatment surface being adapted for complementary fit with the portio of the cervix and comprising a contact surface and a concave portion;(b) a resilient outer portion which is frustoconical in shape, forming a continuous surface that can, in use, adjust its shape to form a secure fit within the walls of the vagina, the outer portion extending away from the treatment surface towards the rear end of the device and tapering outwards such that the widest section of the outer portion is located rearwards of the treatment surface;{'sup': '2', '(c) an array of LEDs sealed within the flexible housing portion, said LEDs being arranged to emit, in use, light with a light intensity of 1-50 mW/cmonto the cervix, wherein the array of LEDs is located beneath the concave portion of the treatment surface; and'}(d) a power supply enclosed in the housing, wherein the device is independently operational while located in the vagina.2. The device according to claim 1 , wherein the flexible housing consists of a first and a second housing portion claim 1 , the first housing portion comprising the treatment surface claim 1 , the resilient outer portion and ...

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Номер записи: 79
23-03-2017 дата публикации

INTRA-ORAL LIGHT-THERAPY APPARATUSES AND METHODS FOR THEIR USE

Номер: US20170080249A1
Автор: Brawn Peter, Bredin Ryan, MARSANYI Robert, Mathews Paul, Shaughnessy Timothy G., Strange Kevin
Принадлежит:

In one or more embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein. 132-. (canceled)33. An apparatus , comprising:a mouthpiece configured to fit within a patient's mouth, the mouthpiece including a bite tray and a flange, the flange coupled to the bite tray, the flange including a top edge continuously spanning from a first end of the bite tray to a second end of the bite tray, the flange not having a notch present therein, the flange having an anterior portion and two posterior portions, the mouthpiece further including one or more grooves in each posterior portion of the flange, the one or more grooves configured to render the flange deflectable toward the bite tray, wherein the one or more grooves are not present in the anterior portion; anda light emitter disposed within the flange, the light emitter configured to emit light to the patient's oral tissue when the mouthpiece is disposed within the mouth.34. (canceled)35. An apparatus , comprising:a mouthpiece configured to fit within a patient's mouth, the mouthpiece including a bite tray and a flange, the flange coupled to the bite tray, the flange spanning from a first end of the bite tray to a second end of the bite tray, the flange having an anterior portion and two posterior portions, the mouthpiece further including one or more grooves in each posterior portion of the flange, ...

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Номер записи: 80
12-03-2020 дата публикации

METHODS FOR TISSUE PASSIVATION

Номер: US20200078159A1
Автор: Austen, JR. William G., Kochevar Irene E., McCormack Michael, Redmond Robert W.
Принадлежит: The General Hospital Corporation

One aspect of the invention provides a method of preventing or reducing stenosis in a subject. The method includes implanting a passivated graft comprising vein into an artery. The implanting of the graft replaces and/or bypasses a diseased segment of the artery. The passivated graft including vein is prepared by exposing the exterior surface of the passivated graft comprising vein to a tissue structure stabilizing agent (“TSSA”) under conditions sufficient to promote cross-linking of proteins within the vein. 1. A method of preventing or reducing stenosis in a subject , the method comprising implanting a passivated graft comprising vein into an artery , wherein the implanting of the graft replaces and/or bypasses a diseased segment of the artery and wherein the passivated graft comprising vein is prepared by exposing the exterior surface of the passivated graft comprising vein to a tissue structure stabilizing agent (“TSSA”) under conditions sufficient to promote cross-linking of proteins within the vein , thereby preventing or reducing stenosis in a subject.2. The method of claim 1 , further comprising exposing the exterior surface of the implanted passivated graft comprising vein and/or the exterior surface of the artery to a tissue structure stabilizing agent (“TSSA”) under conditions sufficient to promote cross-linking of proteins within the exterior surface.3. The method of claim 2 , wherein the diseased segment of the artery contains a plaque.4. The method of claim 1 , wherein the TSSA is a photoactive agent or a chemical cross-linking compound.5. The method of claim 1 , wherein the TSSA is a photoactive agent.6. The method of claim 5 , wherein the photoactive agent is Rose Bengal (“RB”).7. The method of claim 6 , wherein the TSSA does not penetrate more than about 100 μm into connective tissue.8. The method of claim 5 , wherein the photoactive agent is selected from the group consisting of xanthenes claim 5 , flavins claim 5 , thiazines claim 5 , porphyrins ...

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Номер записи: 81
12-03-2020 дата публикации

LASER THERAPEUTIC APPARATUS AND SPINAL CORD REPAIRING METHOD

Номер: US20200078601A1
Автор: DING TAN, WANG Yi
Принадлежит:

A laser therapeutic apparatus includes a laser and a therapeutic optical fiber. The therapeutic optical fiber is configured for being implanted into a body of a patient during surgery to perform a repair treatment on a spinal cord site to-be-treated by irradiation and then being removed from the body of the patient after the surgery. The therapeutic optical fiber includes N number of laser fibers, N−1 number of optical fiber connection components, an optical fiber guiding structure, and an optical fiber controller; the N number of laser fibers are coupled with one another by the N−1 number of optical fiber connection components to form a cascaded optical fiber structure, an end of the cascaded optical fiber structure is coupled to the optical fiber guiding structure, and another end of the cascaded optical fiber structure is coupled to the optical fiber controller. 1. A laser therapeutic apparatus , comprising:a laser; anda therapeutic optical fiber, coupled to the laser and driven by the laser to emit light;wherein the therapeutic optical fiber is configured for being implanted into a body of a patient during surgery to perform a repair treatment on a spinal cord site to-be-treated by light irradiation in a manner of first continuous irradiation and then pulsed irradiation or in a manner of first pulsed irradiation and then continuous irradiation, and then configured for being removed from the body of the patient after the surgery;wherein the therapeutic optical fiber comprises N number of laser fibers each with a predetermined length, N−1 number of optical fiber connection components, an optical fiber guiding structure, and an optical fiber controller; the N number of laser fibers are coupled with one another by the N−1 number of optical fiber connection components to form a cascaded optical fiber structure, an end of the cascaded optical fiber structure is coupled to the optical fiber guiding structure, and another end of the cascaded optical fiber structure is ...

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Номер записи: 82
25-03-2021 дата публикации

ORAL HYGIENE SYSTEM AND METHOD OF USE

Номер: US20210085993A1
Автор: Cameron Colin G., Gillespie Christopher David, Greenwood Martin, Labrecque Martin, McFarland Sherri, McLellan S. Alexander, MORREALE Mark Tullio
Принадлежит:

An oral hygiene device comprises a housing having an outside mouth portion and an inside mouth portion, at least one energy delivery element disposed in or on the inside mouth portion, configured to deliver energy to one or more teeth of a subject, a controller disposed in the outside mouth portion electrically connected to the at least one energy delivery element, an energy storage unit disposed in the outside mouth portion, and a sleeve removably connected to the inside mouth portion of the housing, the sleeve having upper and lower channels configured to accept the upper and lower teeth of the subject. A method of using an oral hygiene device and a method of administering an oral hygiene treatment are also described. 1. An oral hygiene device , comprising:a housing having an outside mouth portion and an inside mouth portion;at least one energy delivery element disposed in or on the inside mouth portion, configured to deliver energy to one or more teeth of a subject;a controller disposed in the outside mouth portion electrically connected to the at least one energy delivery element;an energy storage unit disposed in the outside mouth portion; anda sleeve removably connected to the inside mouth portion of the housing, the sleeve having upper and lower channels configured to accept the upper and lower teeth of the subject.2. The oral hygiene device of claim 1 , further comprising at least one control element disposed on the outside mouth portion.3. The oral hygiene device of claim 1 , further comprising a wireless communication interface electrically connected to the controller and configured to facilitate communication between the controller and computing device external to the oral hygiene device.4. The oral hygiene device of claim 1 , further comprising at least one indicator element disposed in the outside mouth portion.5. The oral hygiene device of claim 4 , wherein the indicator element is an LED.6. The oral hygiene device of claim 1 , wherein the at least one ...

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Номер записи: 83
14-03-2019 дата публикации

Earpiece and method for forming an earpiece

Номер: US20190082272A9
Автор: John Patrick Keady, Paul Calvert, Steven Goldstein
Принадлежит: Staton Techiya LLC

A device includes an electromagnetic radiation delivery system such as a laser of light emitting diode infrared emitter configured for delivery of electromagnetic radiation within a sealed canal such as an ear canal, a fiber optic cable configured for delivering or capturing the electromagnetic radiation within the sealed canal, and a photo detector coupled to the fiber optic cable forming a portion of a voice communication system. Other embodiments are disclosed.

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Номер записи: 84
21-03-2019 дата публикации

APPARATUS AND METHODS USEFUL FOR REMODELING MAXILLOFACIAL BONE USING LIGHT THERAPY, AN ORTHODONTIC APPLIANCE, AND OPTIONALLY, VITAMIN D ADMINISTRATION

Номер: US20190083202A1
Автор: Brawn Peter Robert, CHRISTENSEN Paul, DEMYKIN Alexey, MARSANYI Robert, Mathews Paul, Strange Kevin
Принадлежит: Biolux Research Ltd.

An apparatus includes a mouthpiece sized and shaped to be disposed within a patient's mouth. The mouthpiece includes a bite tray and a flange coupled to the bite tray, the flange being deflectable with respect to the bite tray. A posterior portion of the flange extends beyond a posterior end of the bite tray. The apparatus also includes a light emitter at least partially disposed within the flange. The light emitter is configured to emit light to oral tissue, such as alveolar mucosa, of the patient when the mouthpiece is disposed within the mouth. 1. An apparatus , comprising:a mouthpiece sized or shaped to be disposed within a patient's mouth, the mouthpiece comprising a bite tray and a flange coupled to the bite tray, the flange being deflectable with respect to the bite tray, a posterior portion of the flange posteriorly extending beyond a posterior end of the bite tray; anda light emitter at least partially disposed within the flange, the light emitter configured to emit light to alveolar mucosa of the patient when the mouthpiece is disposed within the mouth.2. The apparatus of claim 1 , the posterior portion of the flange being twistable with respect to an anterior portion of the flange.3. The apparatus of claim 1 , the posterior portion of the flange being flappable with respect to an anterior portion of the flange.4. The apparatus of claim 1 , wherein the light emitter is a first light emitter of a plurality of light emitters claim 1 , the plurality of light emitters being at least partially disposed within the flange and arranged in one or more rows.5. The apparatus of claim 1 , wherein the light emitter is at least partially disposed in the posterior portion of the flange.6. The apparatus of claim 1 , wherein the posterior portion of the flange has a height that is less than a maximum height of an anterior portion of the flange.7. The apparatus of claim 1 , wherein the flange has a height that gradually reduces along a direction extending from an anterior ...

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Номер записи: 85
21-03-2019 дата публикации

Method for sexual stimulation

Номер: US20190083355A1
Автор: Ralph Zipper
Принадлежит: Individual

A sexual stimulation method which may comprise a plurality of light sources for photostimulation of the vagina; one or more vibrators for mechanical stimulation of an area of the vagina; a handle; a controller and programmable memory for containing non-transitory instructions for modes of operation and driving the light sources and vibrators of the invention; a vaginal finger; a handle for ease of use; a keypad for user entry of commands; and a charging or programming port. The invention may also comprise sensors that sense physiologic parameters of a user and adjust sexual stimulation parameters to achieve a desired sexual stimulation effect. Blood oxygen level, temperature, pulse rate and muscle electrical activity may be sensed. The invention also may comprise a flexible covering that provides smooth sliding engagement with an area of the vagina of a user.

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Номер записи: 86
21-03-2019 дата публикации

ELECTRICAL DISCHARGE IRRIGATOR APPARATUS AND METHOD

Номер: US20190083773A1
Автор: Avniel Yuval Charles, Fregoso Gilbert, Heckerman Brad
Принадлежит:

An electrical discharge irrigation includes a power source to produce a first voltage, a circuit coupled to the power source to convert the first voltage to a second voltage, a discharge capacitor to receive the second voltage from the circuit, a transistor and/or a controlled rectifier coupled to the discharge capacitor to receive the second voltage, and an output tip. This tip is coupled to a transistor and/or a controlled rectifier and includes a first end, a second end, a longitudinal axis extending between them, an electrode located in an interior space of the tip to receive an electrical charge from the a transistor and/or a controlled rectifier and to release an electric discharge, and a ground return. The ground return is an outside surface of the tip. A space between the electrode and the ground return holds a conductive medium in contact with the electrode and the ground return. 1. An output tip for an electrical discharge irrigation device , comprising:a first end and a second end and a longitudinal axis extending between them;an electrode located in an interior space of the output tip to receive an electrical charge from a power source;a ground return comprising located on an outside surface of the output tip, wherein disposed between the electrode and the ground return is a conductive medium and wherein the electrode and the ground return are in contact with the conductive medium;an insulating layer comprising at least one perforation, the insulating layer is coupled to one of the electrode and the ground return, wherein the electrode and the ground return are electrically coupled through the at least one perforation to produce an electric discharge; andat least one vent extending through the outside surface of the output tip.2. The output tip of claim 1 , wherein the electrical discharge creates waves within the conductive medium causing the conductive medium to exit the output tip through the at least one vent claim 1 , and wherein the conductive ...

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Номер записи: 87
30-03-2017 дата публикации

FOCAL PHOTODYNAMIC THERAPY METHODS

Номер: US20170087375A1
Автор: Abenhaim Lucien, Charbit Suzy, Gaillac Bertrand
Принадлежит:

Improved methods of treating prostate cancer by vascular-targeted photodynamic therapy, and improved methods of planning treatment, are presented using a light density index to plan and guide effective treatment. 1. A method of treating prostate cancer , comprising:systemically administering a photosensitizing agent to a patient having a prostate tumor;activating the photosensitizing agent by delivering light of appropriate wavelength through at least one optical fiber positioned proximal to the tumor,wherein the dose of light delivered is at or above a prior-determined treatment-effective light density index (LDI) threshold.2. The method of claim 1 , wherein the treatment-effective LDI threshold is prior-determined from historical data from use of the same photosensitizing agent.3. The method of claim 2 , wherein the treatment-effective LDI threshold is prior-determined from historical data from use of the same photosensitizing agent claim 2 , administered at the same systemic dosage.4. The method of claim 3 , wherein the treatment-effective LDI threshold is prior-determined from historical data from use of the same photosensitizing agent claim 3 , administered at the same systemic dosage claim 3 , and same wavelength of delivered light.5. The method of claim 1 , wherein the photosensitizing agent is Palladium 3-oxo-15-methoxycarbonylmethyl-rhodobacteriochlorin 13-(2-sulfoethyl) amide claim 1 , or pharmaceutically acceptable salts thereof.6. The method of claim 5 , wherein the photosensitizing agent is Palladium 3-oxo-15-methoxycarbonylmethyl-rhodobacteriochlorin 13-(2-sulfoethyl) amide dipotassium salt.7. The method of claim 1 , wherein the photosensitizing agent is administered intravenously.8. The method of claim 7 , wherein the photosensitizing agent is Palladium 3-oxo-15-methoxycarbonylmethyl-rhodobacteriochlorin 13-(2-sulfoethyl) amide claim 7 , or pharmaceutically acceptable salts thereof claim 7 , administered intravenously at 3-6 mg/kg.9. The method of ...

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Номер записи: 88
30-03-2017 дата публикации

Transnasal Delivery of Low Level Light Via the Sphenoidal Sinus to Irradiate the Substantia Nigra

Номер: US20170087377A1
Автор: Lovisa Blaise, Pfleiderer Martin, Tardy Yanik S.
Принадлежит:

A transnasal delivery method for treating or preventing Parkinson's disease using photobiomodulation. An optical system is provided including a light source and an optical fiber. The optical system is advanced through the nasal cavity until a distal end of the optical fiber is positioned inside the sphenoidal sinus. Then the light source is activated to irradiate substantia nigra brain tissue with an effective amount of light in the treatment or prevention of Parkinson's disease. 1. A transnasal delivery method for treating or preventing Parkinson's disease using photobiomodulation , comprising the steps of: 'positioning within a nasal cavity a distal end of the optical fiber; and', 'providing an optical system including a light source and an optical fiber;'}activating the light source to irradiate substantia nigra brain tissue with an effective amount of light in the treatment or prevention of Parkinson's disease.2. The method in accordance with claim 1 , wherein the light source has a wavelength in a range of approximately 650 nm-approximately 1000 nm.3. The method in accordance with claim 2 , wherein the light source has a wavelength in a range of approximately 670 nm-approximately 810 nm.4. The method in accordance with claim 1 , wherein the positioning step comprises advancing the distal end of the optical fiber so as to be disposed only within a sphenoidal sinus.5. The method in accordance with claim 1 , wherein the positioning step comprises the steps of:enlarging the sinus; andtransnasal delivery of the optical system to a position in which the distal end of the optical fiber is disposed entirely within the sphenoidal sinus.6. The method in accordance with claim 1 , wherein the substantia nigra is irradiated with a fluence rate between approximately 0.1 mW/cmand approximately 10 mW/cmat different locations inside the substantia nigra.7. The method in accordance with claim 1 , wherein a range of approximately 0.1% to approximately 1.0% of irradiated light ...

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Номер записи: 89
19-06-2014 дата публикации

Dental laser-emitting device and methods

Номер: US20140170588A1
Автор: Alan Miller, Bart Waclawik, William S. Parker
Принадлежит: DENTSPLY INTERNATIONAL INC

Disclosed herein is a dental laser-emitting device capable of treating both soft tissue applications and hard tissue applications.

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Номер записи: 90
19-03-2020 дата публикации

TEETH ILLUMINATION DEVICE WITH A LIGHT MIXING CHAMBER

Номер: US20200085554A1
Автор: BLOEMEN Pascal Jean Henri, VERMEULEN Olaf Thomas Johan Antonie, Young Nigel David
Принадлежит:

The invention relates to an oral care device for teeth whitening or other purpose. The device is designed to provide a uniform light intensity distribution at the teeth by use of a light mixing chamber of a mouthpiece comprised by the oral care device. The mouthpiece comprises a sealing structure with rims designed to connect to the gums of a user. At least apart of the rim and a closure of the mouthpiece surrounded by the rim are reflective. When light is emitted into the mouthpiece, the light will be reflected by the reflective rim, the reflective closure and the buccal side of the teeth. Accordingly, the light will be reflected multiple times, which makes the intensity distribution more uniform. Additionally, the mouthpiece may comprise light redirection structures arranged to redirect light rays from light injected into the mouthpiece. 1. A mouthpiece for teeth illumination , the mouthpiece comprisingan optically transparent body part, wherein the body part has a front side arranged to face a buccal side of the teeth of a user when the mouthpiece is placed in the mouth, and an opposite back side,a sealing structure comprising a rim circumscribing the body part, wherein the rim is shaped to contact gums of a user along upper and lower dental arches, and wherein the rim has a reflective surface arranged to reflect at least a portion of the reflected light from the buccal side of the teeth,one or more light sources arranged to transmit light into at least a portion of the body part,a transmission window located at the front side of the body part and arranged to transmit light from the body part towards the buccal side of the teeth and to transmit reflected light from the buccal side of the teeth into the body part, anda back reflector arranged to reflect incident light from the body part, wherein the reflector extends over at least a portion of the back side of the body part, and wherein the buccal side of the teeth of the user together with the back reflector and ...

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Номер записи: 91
05-05-2022 дата публикации

Photodynamic therapy apparatus for local targeting in cancer treatment and control method therefor

Номер: US20220134125A1
Автор: Brian Wilson, Jae Hyuk Kim, Seung Hee Han, Sung Ho Lee
Принадлежит: Amos Pharm Co Ltd

The present invention relates to a photodynamic therapy apparatus for local targeting in cancer treatment. More specifically, an endoscope is placed in the center of an end portion of a probe used in photodynamic therapy and a plurality of optical fibers are arranged along the edge thereof, so that a lesion site is irradiated with a plurality of lights while the plurality of optical fibers of the probe receive lights from individual light sources, respectively, to perform light irradiation individually. Furthermore, the present invention relates to an apparatus, wherein unnecessary damage to normal tissues is minimized by controlling light irradiation regions, for instance, by defining light irradiation regions encompassing a lesion site from an image provided in real time through an endoscope disposed at an end portion of a probe and allowing only individual light sources irradiating the defined light irradiation regions to emit lights to achieve local light irradiation. Therefore, the photodynamic therapy apparatus for local targeting of the present invention is capable of treating various types of cancers or tumors to which local treatment is applicable due to small-sized lesion sites, including cervical cancer, female cancers (endometrial cancer, ovarian cancer, and breast cancer), skin cancer, brain cancer, and the like.

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Номер записи: 92
05-05-2022 дата публикации

LIGHT IRRADIATING TOOTHBRUSH HAVING MULTIPLE LIGHT SOURCES ARRANGED IN ALTERNATION

Номер: US20220134130A1
Автор: Cha Hee Chan
Принадлежит:

Provided is a light irradiated toothbrush, in which light sources, irradiating light having mutually different wavelengths, are arranged in alternation at the bottom of waveguide bristles so that light of different wavelengths give rise to constructive interference which strengthens the intensity of the irradiated light, and the height of the light sources are varied on the basis of the wavelength of the light irradiated therefrom so as to effectively transmit light of short wavelengths to the waveguide bristles, and light having mutually different wavelengths are transmitted by means of the waveguide bristles, thereby effectively transmitting the light to the mouth of a user.

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Номер записи: 93
12-05-2022 дата публикации

ORAL CARE APPLIANCE WITH LIGHT ILLUMINATION FOR TEETH WHITENING AND GUM HEALTH

Номер: US20220142760A1
Автор: Wang Tianyi
Принадлежит:

An oral appliance having a body, the body including a plate member and a lighting system. The plate member having a first surface, the first surface including a top portion, a center portion, and a bottom portion. The lighting system includes a first lighting sub-system having at least one first light source, where the at least one first light source arranged in the center portion of the plate member, and a second lighting sub-system having at least one second light source, where the at least one second light source arranged in the top portion of the plate member and/or the bottom portion of the plate member. The at least one first light source is arranged to produce a first light at a first wavelength and the at least one second light source is arranged to produce a second light at a second wavelength. 1. An oral care appliance comprising: [ a top portion;', 'a center portion; and', 'a bottom portion; and, 'a plate member having a first surface, the first surface comprising, a first lighting sub-system having at least one first light source, the at least one first light source arranged in the center portion of the plate member;', 'a second lighting sub-system having at least one second light source, the at least one second light source arranged in the top portion of the plate member or the bottom portion of the plate member;, 'a lighting system comprising], 'a body, the body comprisingwherein the at least one first light source is arranged to produce a first light at a first wavelength in the range of 400-495 nm and the at least one second light source is arranged to produce a second light at a second wavelength in the range of 650-1400 nm.2. The oral care appliance of claim 1 , wherein the body further comprises a bite member having a bite surface arranged to contact a user's teeth.3. The oral care appliance of claim 1 , wherein the first surface of the plate member is a curved surface.4. (canceled)5. (canceled)6. The oral care appliance of claim 1 , wherein the ...

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Номер записи: 94
01-04-2021 дата публикации

METHODS AND APPARATUS TO DELIVER THERAPEUTIC NON-ULTRAVIOLET ELECTROMAGNETIC RADIATION FOR AN ENDOTRACHEAL TUBE

Номер: US20210093885A1
Автор: Barneck Mitchell D., de la Presa Martin, Poursaid Arash E., Rhodes Nathaniel L.
Принадлежит:

A therapeutic endotracheal tube assembly is provided for insertion into a patient's trachea to ventilate, to maintain patency of the patient's airway, and to deliver therapeutic electromagnetic radiation (EMR) to the patient. The therapeutic endotracheal tube assembly has an endotracheal tube and an EMR delivery system. The EMR delivery system has an EMR source for emitting non-ultraviolet, therapeutic EMR having intensity sufficient to activate desired therapeutic properties within the patient and an EMR conduction line conducive to the propagation of EMR from the EMR source along the endotracheal tube. The EMR conduction line is removably insertable into the endotracheal tube. The therapeutic endotracheal tube assembly may be custom made or may be constructed by retrofitting a removably insertable EMR delivery system to an existing endotracheal tube. 1. A therapeutic endotracheal tube assembly for insertion into a patient's trachea to ventilate , to maintain patency of the patient's airway , and to deliver therapeutic electromagnetic radiation (EMR) to the patient , the therapeutic endotracheal tube assembly comprising:an endotracheal tube having a lumen defined by a tube wall, a ventilator collar, an upper tube portion having a proximate end coupled to a ventilator collar, and a lower tube portion having a forward end for insertion into the patient's trachea, the endotracheal tube further comprises an inflatable cuff surrounding the tube wall proximate the forward end; and an EMR source for emitting non-ultraviolet, therapeutic EMR having intensity sufficient to activate desired therapeutic properties within the patient;', 'an EMR conduction line conducive to the propagation of EMR from the EMR source along the endotracheal tube, the EMR conduction line having a coupling end and a distal end and being insertable into the endotracheal tube to deliver non-ultraviolet, therapeutic EMR within the patient at sufficient intensity to activate desired therapeutic ...

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Номер записи: 95
28-03-2019 дата публикации

METHOD AND ARRANGEMENT FOR CLEANING OF A CANAL

Номер: US20190090998A1
Автор: DIEBOLDER Rolf, Ertl Thomas
Принадлежит: DENTSPLY SIRONA Inc.

The invention relates to a method and an arrangement for the cleaning of a circumferentially closed canal by means of a light guide conducting a laser beam, wherein the entry of the laser beam into the light guide is interrupted when the free end of the light guide is outside of the canal and/or the movement of the light guide within the canal is monitored and if there is no movement or the movement is below a first threshold value then a signal is triggered and/or the laser radiation is turned off or its output is reduced, and wherein the turning off of the laser radiation or its reducing is controlled in dependency of at least one signal change and/or a second threshold and/or a signal change relative to the second threshold determined during at least one course of time starting before and including the entry of the light guide into the canal. 1. A method for the cleaning of a circumferentially closed canal by means of a light guide conducting a laser beam ,wherein the entry of the laser beam into the light guide is interrupted when the free end of the light guide is outside of the canal and/or the movement of the light guide within the canal is monitored and if there is no movement or the movement is below a first threshold value then a signal is triggered and/or the laser radiation is turned off or its output is reduced, and wherein the turning off of the laser radiation or its reducing is controlled in dependency of at least one signal change and/or a second threshold and/or a signal change relative to the second threshold determined during at least one course of time starting before and including the entry of the light guide into the canal.2. A method according to claim 1 , wherein the turning off of the laser radiation or its reducing is controlled in dependency of at least two signal changes and/or two second thresholds different from each other and/or signal changes relative to the two second thresholds determined during at least two courses of time ...

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Номер записи: 96
28-03-2019 дата публикации

LIGHT-EMITTING DIODE AND MASSAGE DEVICE FOR DELIVERING FOCUSED LIGHT FOR VAGINAL REJUVENATION

Номер: US20190091097A1
Автор: Andersen Roger, Bailey Kevin, Bailey Matthew, Courtion Colette, Klimava Yana, Loebel Nicolas
Принадлежит:

A rejuvenation and massage device is provided for treating mucosa tissue, such as vaginal tissue, affected by Vaginal Relaxation Syndrome (VRS) or other conditions, through vibration, thermal loading, and light emittance for a duration of time. In one embodiment, the device is an insertable device that includes Low-Level Laser Light (LLLT) therapy to treat the vaginal tissue. The light emittance by one or more light emitters is in a range sufficient to provide therapeutic effects through light radiation. To enhance the therapeutic effects of light radiation provided by the device, the device is configured to provide increased energy density into target tissue of vaginal muscles though a light configuration component (e.g., a focusing component, such as a concave lens assembly, a convex assembly, a pre-lensed light emitter or other focusing optical mechanism) associated with the light emitter that concentrates the light emitted from the light emitter. 1. A device for tissue rejuvenation therapy , the device comprising: a first shell portion forming an external surface of the insertable body and composed of a silicone material,', 'a second shell portion within the first shell portion and composed at least partially of an opaque material, the first and the second shell portions also defining a treatment window forming a band about a portion of the insertable body;, 'an insertable body that is insertable into a cavity, the insertable body comprising a set of light emitters radially distributed about a longitudinal axis within the within the insertable body and positioned at the treatment window, and', 'a set of focusing components, positioned at the treatment window, that focus light emitted from the set of light emitters onto a mucosa tissue within the cavity, during operation, to provide adjustment of light transmission to the mucosa tissue within the cavity; and, 'a light emitting subsystem within the insertable body, the light emitting subsystem comprisinga ...

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Номер записи: 97
06-04-2017 дата публикации

Methods and devices to treat nasal airways

Номер: US20170095288A1
Автор: Andrew Frazier, Scott J. Wolf
Принадлежит: Aerin Medical Inc

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

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Номер записи: 98
06-04-2017 дата публикации

Light-Emitting Diode and Massage Device for Delivering Focused Light for Vaginal Rejuvenation

Номер: US20170095398A1
Автор: Andersen Roger, Bailey Kevin, Bailey Matthew, Courtion Colette, Klimava Yana, Loebel Nicolas
Принадлежит:

A rejuvenation and massage device is provided for treating mucosa tissue, such as vaginal tissue, affected by Vaginal Relaxation Syndrome (VRS) or other conditions, through vibration, thermal loading, and light emittance for a duration of time. In one embodiment, the device is an insertable device that includes Low-Level Laser Light (LLLT) therapy to treat the vaginal tissue. The light emittance by one or more light emitters is in a range sufficient to provide therapeutic effects through light radiation. To enhance the therapeutic effects of light radiation provided by the device, the device is configured to provide increased energy density into target tissue of vaginal muscles though a light configuration component (e.g., a focusing component, such as a concave lens assembly, a convex assembly, a pre-lensed light emitter or other focusing optical mechanism) associated with the light emitter that concentrates the light emitted from the light emitter. 1. A rejuvenation and massage device comprising:an insertable device having at least one contact surface and being insertable into a vagina; one or more light emitters arranged around a portion of the insertable device that is insertable into the vagina, the one or more light emitters configured to emit light onto tissue within the vagina, and', 'a light configuration component configured to focus the light emitted from the one or more light emitters onto the tissue; and, 'a light emitting mechanism integrated within the insertable device, the light emitting mechanism comprisinga vibration mechanism integrated within the insertable device configured to provide vibration to the tissue within the vagina to induce a pleasure response and tone muscle.2. The device of claim 1 , further comprising:a safety temperature mechanism integrated within the insertable device, the safety temperature mechanism including a thermocouple assembly for thermal overload detection;a cooling mechanism integrated within the insertable device;a ...

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Номер записи: 99
16-04-2015 дата публикации

Method for endoscopic treatment

Номер: US20150105614A1
Автор: IGARASHI Makoto, TAKEKOSHI Satoshi
Принадлежит: OLYMPUS MEDICAL SYSTEMS CORP.

A method for endoscopic treatment that performs treatment on a subject under an endoscope includes irradiating the subject with white light, switching, after irradiation with the white light, to irradiation of a living tissue of the subject with band-limited light having a predetermined peak wavelength, and administering medicine to the subject after irradiation with the band-limited light. 1. A method for endoscopic treatment that performs treatment on a subject under an endoscope , the method comprising:irradiating the subject with white light;switching, after irradiation with the white light, to irradiation of a living tissue of the subject with band-limited light having a predetermined peak wavelength; andadministering medicine to the subject after irradiation with the band-limited light.2. The method for endoscopic treatment according to claim 1 , wherein the medicine is administered by locally injecting a sclerosing agent into varices of the subject via a local injection needle.3. The method for endoscopic treatment according to claim 1 , wherein the medicine is administered by locally injecting inflammation treatment medicine into an inflamed mucous membrane of the object via a local injection needle or spraying inflammation treatment medicine over an inflamed mucous membrane of the subject using a spray probe.4. The method for endoscopic treatment according to claim 1 , wherein the medicine is administered by locally injecting inflammation treatment medicine into an inflamed mucous membrane of the object via a local injection needle or spraying inflammation treatment medicine over a region of interstitial cystitis of the subject using a spray probe.5. The method for endoscopic treatment according to claim 1 , further comprising performing claim 1 , after irradiation with the band-limited light claim 1 , hemostasis treatment on a bleeding blood vessel of the living tissue using an electric scalpel or hemostasis forceps.6. The method for endoscopic treatment ...

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Номер записи: 100