A modular flow reactor

Welded microchannel processor

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

High throughput microfluidic device

A microfluidic element comprising at least one pair of plates, at least one of said plates having an open channel distributed on a surface that is adjacent the other plate in the pair. In use, said plates are releasably clamped together so as to form an enclosed, continuous microfluidic channel between the plates that is suitable for the passage of a fluid.

REACTOR SYSTEM FOR PRODUCING HYDROCARBONS FROM SYNTHETIC GAS

The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.

용접된 마이크로채널 프로세서

The present invention comprises a plurality of laminated plates forming at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, said peripheral edge of each plate having a peripheral seal The ratio of the average surface area of each adjacent plate to the average penetration of welds between adjacent plates is at least about 100 cm2 / mm. The stack can be used as a core assembly for a microchannel processor. The microchannel processor may be used to perform one or more unit operations involving chemical reactions such as SMR reactions.

HEAT EXCHANGE REACTOR AND METHOD FOR PRODUCING SAME

The present invention relates to a heat exchange reactor and a method for producing the same. The method comprises the steps of: preparing a side surface plate having a plurality of slits horizontally formed along a length direction; disposing two side surface plates to be spaced apart from each other and face each other in a vertical direction; producing a plurality of flow path channels by horizontally fitting a flow path diaphragm into at least one of the slits of the side surface plates in a horizontal direction; producing a plurality of flow path channels by horizontally fitting a printed circuit-type heat exchange plate autonomously including a least one heat exchange flow path therein into at least one of the slits of the side surfaces plates in a horizontal direction; and joining the side surface plates, the flow path diaphragm, and the printed circuit-type heat exchange plate with each other. A separate heat exchange flow path channel, a separate heat exchange structure, and a ...

sistemas para a produção de um produto químico

AUTOMATIC DEVICE FOR THE SYNTHESIS OF PEPTIDE-BASED RADIOACTIVE DRUGS FOR DIAGNOSTIC AND/OR THERAPEUTIC USE

The present invention concerns an automatic device for the synthesis of peptide-based radioactive drugs, for diagnostic and/or therapeutic use, comprising: - a structure frame (100); - a possible closing case (200) for said structure frame (100); - a first disposable main module (1 ); - a second disposable module (19), slidingly associated with said first main module (1); - a third disposable test-tube holder module (26), reversibly fixable to said structure frame (100) with fixing means that allow the translation thereof with respect to the same. Said first (1), second (19) and third (26) module are arranged for irreversibly coupling so as to form one single disposable collector (300) inside which the whole synthesis process of the concerned radioactive drug is performed, where at the end of the process, said collector (300) may be removed from the device as one single contaminated mono block. The device is controlled by a remote control and drive workstation (39) that comprises a personal computer (PC) through which the operator may interact with the whole synthesis process, as well as devices (PE) for storing and managing the data concerning the synthesis of the specific radioactive drug obtained for each single treated patient.

MICROSTRUCTURE COMPONENT AND METHOD FOR THE PRODUCTION THEREOF

The invention relates to a microstructure component for conducting a fluid and to a method for the production thereof, in which a metal sheet (110) is guided through a gap between a pair of profiled rollers (100) and is thereby microstructured, wherein a wave profile (221) is created in the direction of the width, a microstructured plate (212, 216) is cut to length from the metal sheet (110), a solder (220) is applied to an unstructured plate (210, 214, 218), the microstructured plate (212, 216) and the unstructured plate (210, 214, 218) are put together to form a stack (200) and the stack (200) is connected by means of vacuum soldering. The microstructure component has microstructured plates (212, 216) and unstructured plates (210, 214, 218) stacked alternately one on top of the other, wherein the microstructured plates (212, 216) have a wave profile (221) that respectively has channel-shaped depressions (226) in the region of the crests, wherein between the microstructured plates and ...

Processing Apparatus Fabrication

A processing apparatus that is formed from a plurality of metal layers that are stacked and aligned together and then connected together to form one or more portions of the processing apparatus.

МИКРОКАНАЛЬНОЕ ТЕХНОЛОГИЧЕСКОЕ УСТРОЙСТВО

1. Устройство, содержащее:пластины, собранные в пакет и определяющие по меньшей мере один процессный слой и по меньшей мере один теплообменный слой, причемкаждая пластина содержит активную область, граничную область, окружающую по меньшей мере часть активной области, и периферийный край, периферийный край и часть граничной области каждой пластины приварены к периферийному краю и части граничной области следующей соседней пластины для удержания пакета вместе и обеспечения периферийного уплотнения пакета, аотношение средней площади поверхности каждой из соседних пластин к средней глубине проникновения сварочного шва между соседними пластинами составляет по меньшей мере примерно 100 см/мм, или от примерно 100 см/мм до примерно 100000 см/мм, или от примерно 100 см/мм до примерно 2000 см/мм.2. Устройство по п.1, в котором:процессный слой содержит катализатор парового преобразования метана, а теплообменный слой содержит катализатор горения.3. Устройство по п.1 или 2, в которомпакет размещен в оболочке, причемпакет выполнен с возможностью работы при внутреннем давлении, превышающем атмосферное давление,оболочка выполнена с возможностью работы при внутреннем давлении, превышающем атмосферное давление, обеспечивает возможность приложения давления к внешней поверхности пакета исодержит управляющее устройство для поддержания внутри нее по меньше мере такого давления, как внутреннее давление внутри пакета,или в котором на внешней части пакета расположен жесткий внешний каркас с обеспечением конструктивной поддержки пакета,или в котором к каждой стороне пакета присоединены оконечные пластины с обеспечением конструктивн�

Mikrostrukturbauteil und Verfahren zu dessen Herstellung

Die Erfindung betrifft ein Mikrostrukturbauteil zum Leiten eines Fluids und ein Verfahren zu dessen Herstellung, bei dem ein Blech (110) durch einen Spalt eines Profil-Walzenpaares (100) geführt und dabei mikrostrukturiert wird, wobei ein Wellenprofil (221) in Breitenrichtung erzeugt wird, aus dem Blech (110) eine mikrostrukturierte Platte (212, 216) abgelängt wird, auf eine unstrukturierte Platte (210, 214, 218) ein Lot (220) aufgebracht wird, die mikrostrukturierte Platte (212, 216) und die unstrukturierte Platte (210, 214, 218) zu einem Stapel (200) zusammengesetzt werden und der Stapel (200) mittels Vakuumlöten verbunden wird. Das Mikrostrukturbauteil weist abwechselnd aufeinander gestapelte mikrostrukturierte Platten (212, 216) und unstrukturierte Platten (210, 214, 218) auf, wobei die mikrostrukturierten Platten (212, 216) ein Wellenprofil (221) aufweisen, das jeweils im Scheitelbereich rillenförmige Einbuchtungen (226) aufweist, wobei Lotverbindungen zwischen den mikrostrukturierten ...

Mikrokanalapparatur

Diese Erfindung bezieht sich auf eine Vorrichtung, die Folgendes umfasst: eine Vielzahl von Platten in einem Stapel, der wenigstens eine Prozessschicht und wenigstens eine Wärmeaustauschschicht definiert, wobei jede Platte einen umlaufenden Rand aufweist, wobei der umlaufende Rand jeder Platte an den umlaufenden Rand der nächstbenachbarten Platte geschweißt ist, so dass man eine Umfangsabdichtung des Stapels erhält, wobei das Verhältnis der mittleren Fläche jeder der benachbarten Platten zur mittleren Eindringtiefe des Schweißmaterials zwischen den benachbarten Platten wenigstens etwa 100 cm2/mm beträgt. Der Stapel kann als Kernbaugruppe für eine Mikrokanalapparatur verwendet werden. Die Mikrokanalapparatur kann verwendet werden, um einen oder mehrere Arbeitsschritte einschließlich chemischer Reaktionen, wie SMR-Reaktionen, durchzuführen.

Welded microchannel processor

Synthesis gas conversion process

A method is disclosed for restarting a synthesis gas conversion process which has stopped. The method involves flowing synthesis gas into a reactor in contact with a synthesis gas conversion catalyst at a desired reaction temperature and pressure to produce a synthesis gas product and flowing effluent comprising the synthesis conversion product out of the reactor, the method comprising: (A) stopping the flow of the synthesis gas into the reactor, (B) flowing hydrogen or natural gas into the reactor to purge the reactor; and (c) restarting the flow of synthesis gas into the reactor. The synthesis gas conversion process may be conducted in a conventional reactor or a microchannel reactor. The synthesis gas conversion process may comprise a process for converting synthesis gas to methane, methanol or dimethyl ether. The synthesis gas conversion process may be a Fischer-Tropsch process.

Surface functionalization

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

MICROCHANNEL PROCESSOR

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

FLUIDIC MODULE SUSPENSION SYSTEM AND RESULTING REACTOR

A modular reactor (10) includes a plurality of planar fluidic modules (12) arranged in a spaced-apart horizontally extending row extending in a direction D with the major surfaces (14, 16) of the modules (12) oriented generally parallel to each other. A plurality of rigid or semi-rigid fluid connectors (30) are each positioned between facing major surfaces (14, 16) of the modules, and the connectors (30) fluidically and mechanically join at least one fluid port (18a) on a first surface (24) of the facing surfaces to at least one other fluid port (18b) on a second surface (26) of the facing surfaces (14,16). The reactor (10) further comprises a horizontally extending support structure (60) extending above the row of modules (12) in the direction D, and one or more hangers (32) each supporting one of the plurality of fluidic modules (12) from the support structure (60). The hangers (32) comprise a first rotary joint (34) having a first axis (36) positioned above the respective module (12) ...

A MODULAR FLOW REACTOR

A modular flow reactor is formed of a plurality of modules, wherein each module comprises a body having at least one conduit passing therethrough, and wherein a plurality of said modules are aligned along a longitudinal axis such that said conduits of said modules are aligned to form a passage for fluid, wherein each module has a length along said longitudinal axis which is less than the length of the module perpendicular to the longitudinal axis. The modules are "slices" rather than "tubes" and a plurality of said modules can be aligned linearly so that the conduits form a tube.

LAMINATED, LEAK-RESISTANT CHEMICAL PROCESSORS, METHODS OF MAKING, AND METHODS OF OPERATING

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

Microchannel reactors and fabrication processes

A method of loading material within a microchannel device, the method comprising: (a) loading particulates into a plurality of microchannels; and, (b) ultrasonically packing the particulates into the plurality of microchannels using a portable, compact ultrasonic densification unit.

СЛОИСТЫЕ, УСТОЙЧИВЫЕ К УТЕЧКАМ ХИМИЧЕСКИЕ РЕАКТОРЫ, СПОСОБЫ ПРОИЗВОДСТВА И СПОСОБЫ ЭКСПЛУАТАЦИИ

... 1. Слоистый микроканальный узел, включающий первый лист и второй лист; отличающийся тем, что каждый лист имеет длину и ширину, причем площадь поперечного сечения, определяемая как произведение длины листа на ширину листа, превышает 100 см;отличающийся тем, что первый и второй листы являются по существу плоскими;первый лист содержит систему параллельных микроканалов, причем микроканалы отделены друг от друга перегородкой;первый лист и второй лист являются смежными;и включающий сварные швы, которые проходят по длине перегородок и соединяют первый лист со вторым листом.2. Узел по п.1, отличающийся тем, что площадь поперечного сечения, определяемая как произведение длины листа на ширину листа, превышает 500 см.3. Узел по п.1, отличающийся тем, что сварные швы являются непрерывными.4. Узел по п.1, отличающийся тем, что сварные швы на втором листе имеют линейную плотность, по крайней мере, 2,7 см/см.5. Узел по п.1, отличающийся тем, что сварные швы являются лазерными сварными швами, имеющими ...

Laminated, leak-resistant chemical processors, methods of making, and methods of operating

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

Laminated, Leak-Resistant Chemical Processors, Methods of Making, and Methods of Operating

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the 5 inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described. Fig. 6 Fig. 7 ...

LAMINATED, LEAK-RESISTANT CHEMICAL PROCESSORS, METHODS OF MAKING, AND METHODS OF OPERATING

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

Mikrokanalreaktoren und Herstellungsverfahren

Ein Mikrokanalreaktor, umfassend: (a) eine Mehrzahl von Prozessmikrokanälen mit Partikeln, die entlang der Länge der Mikrokanäle gepackt sind; (b) eine Mehrzahl von Wärmeübertragungsmikrokanälen in thermischer Verbindung mit der Mehrzahl von Prozessmikrokanälen; und, (c) einen ersten Halter, der an einem ersten Ende der Mehrzahl von Prozessmikrokanälen positioniert ist, um die Partikel an einem Austritt aus den Prozessmikrokanälen über das erste Ende zu hindern.

Mikroreaktor für photokatalytische Reaktionen

Die vorliegende Erfindung bezieht sich auf eine Vorrichtung zur photokatalytischen Reduktion einer Substanz mit einer strukturierten Reaktionsplatte und/oder einem strukturierten Gehäuse, wobei die Reaktionsplatte zumindest bereichsweise eine Oberfläche aufweist, die ein Material mit negativer Elektronenaffinität enthält und die mit Strahlung einer Wellenlänge von ≥ 180 nm elektronisch angeregt werden kann. The present invention relates to a device for the photocatalytic reduction of a substance with a structured reaction plate and / or a structured housing, wherein the reaction plate at least partially has a surface containing a material with negative electron affinity and with radiation having a wavelength of ≥ 180 nm can be excited electronically.

A method of loading material within a microchannel device

Laminated, leak-resistant chemical processors, methods of making, and methods o operating

WELDED MICROCHANNEL PROCERSSOR

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

SURFACE FUNCTIONALIZATION

CA 3069742 Abstract The invention pertains to methods of functionalizing the surface of an enclosed microfluidic channel. The methods comprise exposing a portion of an unmodified surface of the microfluidic channel to a bifunctional crosslinker, activating said crosslinker to create a crosslinked surface, and exposing the crosslinked surface of a surface hydrophobicity modifying molecule to create a functionalized surface. Date Recue/Date Received 2021-01-08 ...

MODULAR MICROPLASMA MICROCHANNEL REACTOR DEVICES, MINIATURE REACTOR MODULES AND OZONE GENERATION DEVICES

A preferred modular microplasma microchannel reactor device includes a microchannel array arranged with respect to electrodes for generation of plasma and isolated by dielectric from the electrodes. A cover covers a central portion of the microchannel array, while leaving end portions of the microchannel array exposed. A gas inlet and product outlet are arranged to permit flow into, through and out of the microchannel array. Reactor modules of the invention include pluralities of the modular reactor devices. The reactors devices can be arranged by a housing or a frame to be in fluid communication. A system of the invention arranges pluralities of modules. Preferred module housings, frames and reactors include structural features to create alignments and connections. Preferred modules include fans to circulate feedstock and reaction product. Other reactor devices provide plasma actuation for flow.

MICROCHANNEL PROCESSOR

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

REACTOR SYSTEM FOR PRODUCING HYDROCARBONS FROM SYNTHETIC GAS

The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.

METHOD AND DEVICE FOR MANUFACTURING OF RADIOPHARMACEUTICALS

The invention relates to a device for processing radioisotopes and production of radiopharmaceuticals, for example, 18F-2 Deoxy-2-Fluoro-D-Glucose (FDG), for Positron Emission Tomography (PET). Use of a tilting and rotating reactor with optimized geometry allows for decreased processing time and increased efficiency. Reagent vials are separated from the reactor module and placed in a separate enclosure allowing safe reloading of the system and production of multiple batches with minimal operator exposure to radiation. Reagent vials enclosure is protected from the environment and filled with purified air to reduce risk of contamination. Product and reagents pathways are sealed from the environment and are sterilized.

SURFACE FUNCTIONALIZATION

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

REACTOR SYSTEM AND PROCESS FOR FLOW-THROUGH REACTIONS

Laminated, leak-resistant chemical processors, methods of making, and methods of operating

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

High throughput microfluidic device

Reactor

LAMINATED, LEAK-RESISTANT CHEMICAL PROCESSORS, METHODS OF MAKING, AND METHODS OF OPERATING

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

MICROCHANNEL REACTORS AND FABRICATION PROCESSES

A method and apparatus for loading catalyst and optionally dislodging spent catalyst within a microchannel reactor, the method comprising: (a) loading active catalyst into a plurality of reactant inicrochannels; and, (b) ultrasonically packing the active catalyst into the pluralily of reactant microchannels using a portable, compact ultrasonic densification unit.

MICROCHANNEL REACTORS AND FABRICATION PROCESSES

A microchannel reactor comprising: (a) a plurality of process microchannels having particulates packed along the length of the microchannels; (b) a plurality of heat transfer microchannels in thermal communication with the plurality of process microchannels; and, (c) a first retainer positioned at a first end of the plurality of process microchannels to inhibit the particulates from exiting the process microchannels via the first end.

모듈식 마이크로플라즈마 마이크로채널 반응기 디바이스, 소형 반응기 모듈, 및 오존 발생 디바이스

... 바람직한 모듈식 마이크로플라즈마 마이크로채널 반응기 디바이스는 플라즈마 생성을 위한 전극들에 대하여 배치되며, 상기 전극들로부터 유전체에 의해 격리된 마이크로채널 어레이를 포함한다. 커버는 상기 마이크로채널 어레이의 중앙부를 덮으면서, 상기 마이크로채널 어레이의 단부들은 노출시킨다. 기체 유입구 및 생성물 배출구는 상기 마이크로채널 어레이 내로, 상기 마이크로채널 어레이를 통하여, 그리고 상기 마이크로채널 어레이의 밖으로 플로우(flow)를 허용하도록 배치된다. 본 발명의 반응기 모듈들은 복수의 모듈식 반응기 디바이스들을 포함한다. 상기 반응기 디바이스들은 하우징 또는 프레임에 의해 유체 상통되도록 배열될 수 있다. 본 발명의 시스템들은 복수의 모듈들을 배열한다. 바람직한 모듈 하우징들, 프레임들, 및 반응기들은 정렬들 및 연결들을 형성하기 위해 구조적인 요소들을 포함한다. 바람직한 모듈들은 공급물과 반응 생성물을 순환시키기 위해 팬들을 포함한다. 다른 반응기 디바이스들은 플로우를 위한 플라즈마 액추에이션을 제공한다.

PHOTOREACTION MICRO REACTOR

　光反応マイクロリアクタ（１０１）は、ハウジング上部（１０２）と、光を透過する材質からなるフタプレート（１０３）と、光の反射を抑制し、かつ熱伝導性の高い材質からなる流路プレート（１０４）と、ハウジング下部（１０５）とを備える。ハウジング上部（１０２）の窓部及びフタプレート（１０３）を介して光が流路プレート（１０４）の流路（１０９）に光が照射される。光を透過する材質からなるフタプレート（１０３）と、光の反射を抑制し、かつ熱伝導性の高い材質からなる流路プレート（１０４）とは、溶着され互いに一体となっている。

MICRO CHANNEL REACTOR WITH INTEGRAL HEATING ELEMENTS

In one example disclosed in the current application, by supplying just enough heat to the channel walls to replace the reaction heat removed during the reaction, a reactor exhibits tighter temperature tolerances with respect to the desired reaction temperature. In other words, the surface temperature can be more closely matched to the desired reaction temperature. Also, having a design where the channels can be scaled in both geometry and number allows control of the rate of mass transport through the channels to minimize unwanted side reactions.

MULTI-PHASE OSCILLATORY FLOW REACTOR

According to some aspects, described herein is an automated droplet-based reactor that utilizes oscillatory motion of a droplet in a tubular reactor under inert atmosphere. In some cases, such a reactor may address current shortcomings of continuous multi-phase flow platforms.

Microchannel reactors and fabrication processes

A cylindrical microchannel device

Surface functionalization

Laminated, leak-resistant chemical processors, methods of making, and methods of operating

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

HIGH THROUGHPUT MICROFLUIDIC DEVICE

A microfluidic element comprising at least one pair of plates, at least one of said plates having an open channel distributed on a surface that is adjacent the other plate in the pair. In use, said plates are releasably clamped together so as to form an enclosed, continuous microfluidic channel between the plates that is suitable for the passage of a fluid.

MICRO-REACTOR FOR CARRYING OUT CHEMICAL REACTIONS

The invention relates to a micro-reactor, comprising: n process plate units, with n ≥ 1, comprising each at least one reactive fluid passage which penetrates said process plate unit for accommodating and guiding a reactive fluid between at least one reactive fluid inlet port and at least one reactive fluid outlet port thereof; and m heat exchange plate units, with m ≥ 2, comprising each at least one heat exchange fluid passage which penetrates said heat exchange plate unit for accommodating and guiding a heat exchange fluid between at least one heat exchange fluid inlet port and at least one heat exchange fluid outlet port thereof; wherein k modules, with k ≥ 1, as smallest replaceable entity of said micro-reactor, are each formed of either a single one or a plurality of the sum of said n process plate units and m heat exchange plate units; wherein said k modules are arranged to form a stack, and wherein at least two of said m heat exchange plate units forming said stack are fluidically connected in parallel with each other by one or more heat exchange fluid connecting passages arranged within said stack; and wherein, within said stack, each of said n process plate units is in thermal contact with at least one of said m heat exchange plate units.

Microchannel processor

Microchannel reactors and fabrication processes

A method and apparatus for loading catalyst and optionally dislodging spent catalyst within a microchannel reactor, the method comprising: (a) loading active catalyst into a plurality of reactant inicrochannels; and, (b) ultrasonically packing the active catalyst into the pluralily of reactant microchannels using a portable, compact ultrasonic densification unit.

Microchannel reactors and fabrication processes

A microchannel reactor comprising: (a) a plurality of process microchannels having particulates packed along the length of the microchannels; (b) a plurality of heat transfer microchannels in thermal communication with the plurality of process microchannels; and, (c) a first retainer positioned at a first end of the plurality of process microchannels to inhibit the particulates from exiting the process microchannels via the first end.

Microchannel reactors and fabrication processes

SURFACE FUNCTIONALIZATION

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

MICROCHANNEL REACTORS AND FABRICATION PROCESSES

A method and apparatus for loading catalyst and optionally dislodging spent catalyst within a microchannel reactor, the method comprising: (a) loading active catalyst into a plurality of reactant inicrochannels; and, (b) ultrasonically packing the active catalyst into the pluralily of reactant microchannels using a portable, compact ultrasonic densification unit.

AUTOMATIC DEVICE FOR THE SYNTHESIS OF PEPTIDE-BASED RADIOACTIVE DRUGS FOR DIAGNOSTIC AND/OR THERAPEUTIC USE

The present invention concerns an automatic device for the synthesis of peptide-based radioactive drugs, for diagnostic and/or therapeutic use, comprising: - a structure frame (100); - a possible closing case (200) for said structure frame (100); - a first disposable main module (1 ); - a second disposable module (19), slidingly associated with said first main module (1); - a third disposable test-tube holder module (26), reversibly fixable to said structure frame (100) with fixing means that allow the translation thereof with respect to the same. Said first (1), second (19) and third (26) module are arranged for irreversibly coupling so as to form one single disposable collector (300) inside which the whole synthesis process of the concerned radioactive drug is performed, where at the end of the process, said collector (300) may be removed from the device as one single contaminated mono block. The device is controlled by a remote control and drive workstation (39) that comprises a personal ...

Fluid connector devices and methods of making and using the same

A fluid connector device (10) is provided. The fluid connector device includes a coupling substrate (12) having a conformal recess (20), a reconnectable fitting (18) disposed in the recess to provide a first passageway, and a force applying element (16) operatively coupled to the reconnectable fitting (18), or the coupling substrate (12), or both the reconnectable fitting (18) and the coupling substrate (12) to at least partially provide a sealing force between the reconnectable fitting (18) and the coupling substrate (12), wherein at least one of the force applying element (16), the reconnectable fitting (18), and the coupling substrate (12) comprises one or more degrees of freedom for self alignment of the reconnectable fitting (18) and the conformal recess (12).

MICROREACTOR FOR PHOTOCATALYTIC REACTIONS

The present invention relates to a device for the photocatalytic reduction of a substance with a structured reaction plate and/or a structured housing, wherein the reaction plate has, at least in some regions, a surface which contains a material with negative electron affinity and which can be electronically excited with radiation having a wavelength of ≥180 nm. 125-. (canceled)26. A device for photocatalytic reduction of a substance comprisingat least one reactor housing with a reaction plate disposed therein,the reaction plate and/or the reactor housing having a structuring and being insulated electrically from each other,the reactor housing consisting, at least in regions, of a material which is transparent for radiation of a wavelength of ≥180 nm,and the reaction plate having, at least in regions, a surface which comprises a material with negative electron affinity and which can be excited electronically with radiation of a wavelength of ≥180 nm.27. The device according to claim 26 , wherein the structuring of the reaction plate and/or of the reactor housing are/is suitable for the transport of a liquid thin film with a film thickness of max. 120 μm.28. The device according to claim 26 , wherein the structuring comprises at least one channel-like depression.29. The device according to claim 28 , wherein the at least one channel-like depression extends along a preferential flow direction of the liquid thin film.30. The device according to claim 26 , wherein the material with negative electron affinity is selected from the group consisting of doped or pure diamond claim 26 , boron nitride claim 26 , silicon carbide claim 26 , gallium nitride claim 26 , gallium arsenide claim 26 , and mixtures thereof.31. The device according to claim 26 , wherein the material with negative electron affinity is bonded covalently to at least one photosensitizer.32. The device according to claim 31 , wherein the at least one photosensitizer is a compound with an absorption wavelength ...

MICROCHANNEL PROCESSOR

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm 2 /mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

FLUIDIC MODULE SUSPENSION SYSTEM AND RESULTING REACTOR

FLUID CONNECTOR DEVICES AND METHODS OF MAKING AND USING THE SAME

WELDED MICROCHANNEL PROCERSSOR

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

Surface functionalization

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

Microchannel reactors and fabrication processes

A method and apparatus for loading catalyst and optionally dislodging spent catalyst within a microchannel reactor, the method comprising: (a) loading active catalyst into a plurality of reactant inicrochannels; and, (b) ultrasonically packing the active catalyst into the pluralily of reactant microchannels using a portable, compact ultrasonic densification unit.

Laminated, leak-resistant chemical processors, methods of making, and methods of operating

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

Fluid connector device and method for making and using same

MICROCHANNEL PROCESSOR

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

MICROCHANNEL REACTORS AND FABRICATION PROCESSES

A microchannel reactor comprising: (a) a plurality of process microchannels having particulates packed along the length of the microchannels; (b) a plurality of heat transfer microchannels in thermal communication with the plurality of process microchannels; and, (c) a first retainer positioned at a first end of the plurality of process microchannels to inhibit the particulates from exiting the process microchannels via the first end.

MICROREACTOR FOR PHOTOREACTIONS

A microreactor for photoreactions includes a housing upper part, a lid plate made of a material that allows transmission of light, a flow path plate made of a material that suppresses light reflection and has a high thermal conductivity, and a housing lower part. Light is applied through a window of the housing upper part and the lid plate to a flow path of the flow path plate. The lid plate made of the material that allows transmission of light and the flow path plate made of the material that suppresses light reflection and has a high thermal conductivity are welded each other to form an integrated body.

SYNTHESIS GAS CONVERSION PROCESS

The disclosed invention relates to a method for restarting a synthesis gas conversion process which has stopped. The synthesis gas conversion process may be conducted in a conventional reactor or a microchannel reactor. The synthesis gas conversion process may comprise a process for converting synthesis gas to methane, methanol or dimethyl ether. The synthesis gas conversion process may be a Fischer-Tropsch process.

Synthesis gas conversion process

Surface functionalization

LAMINATED, LEAK-RESISTANT CHEMICAL PROCESSORS, METHODS OF MAKING, AND METHODS OF OPERATING

MICROCHANNEL REACTORS AND FABRICATION PROCESSES

A method and apparatus for loading catalyst and optionally dislodging spent catalyst within a microchannel reactor, the method comprising: (a) loading active catalyst into a plurality of reactant inicrochannels; and, (b) ultrasonically packing the active catalyst into the pluralily of reactant microchannels using a portable, compact ultrasonic densification unit.

REACTOR INCORPORATING A HEAT EXCHANGER

A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath.

Mikrokanalreaktoren und Herstellungsverfahren

Ein Verfahren und ein Apparat zum Laden eines Katalysators und optional Lösen eines verbrauchten Katalysators in einem Mikrokanalreaktor, wobei das Verfahren umfasst: (a) Laden eines aktiven Katalysators in eine Mehrzahl von Reaktanten-Mikrokanäle; und, (b) Ultraschall-Packen des aktiven Katalysators in die Mehrzahl von Reaktanten-Mikrokanäle unter Verwendung einer tragbaren, kompakten Ultraschall-Verdichtungseinheit.

A laminated microchannel assembly, and a method of forming the laminated microchannel assembly by welding

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to 5 fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

Plate-type heat exchanger reactor and method for producing the same

... 본 발명은 평판형 열교환 반응기 및 이의 제조방법에 관한 것으로, 길이방향을 따라 평행하게 형성되는 복수의 슬릿을 구비하는 측면판을 준비하는 단계; 2개의 측면판을 수직방향으로 마주보도록 이격 배치하는 단계; 두 측면판의 각 슬릿에 복수의 유로 격판을 수평방향으로 평행하게 끼워 복수의 유로 채널을 형성하는 단계; 및 측면판과 유로 격판을 접합하는 단계를 포함하는 평판형 열교환 반응기의 제조방법 그리고 이 제조방법에 제조되는 평판형 열교환 반응기를 제공한다.

WELDED MICROCHANNEL PROCESSOR

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

Reactor incorporating a heat exchanger

A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath.

Surface functionalization

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

High throughput microfluidic device

A microfluidic element comprising at least one pair of plates, at least one of said plates having an open channel distributed on a surface that is adjacent the other plate in the pair. In use, said plates are releasably clamped together so as to form an enclosed, continuous microfluidic channel between the plates that is suitable for the passage of a fluid.

Microchannel reactors and fabrication processes

A method and apparatus for loading catalyst and optionally dislodging spent catalyst within a microchannel reactor, the method comprising: (a) loading active catalyst into a plurality of reactant inicrochannels; and, (b) ultrasonically packing the active catalyst into the pluralily of reactant microchannels using a portable, compact ultrasonic densification unit.

미소 유체 컴포넌트, 복수의 그러한 컴포넌트를 포함하는 반응기, 및 그들을 생산하는 방법

이 발명은 미소 유체 컴포넌트에 관한 것으로서, 폐쇄된 유체 라인을 포함하고, 금속 시트의 제1 섹션의 구조화 표면 및 금속 시트의 제2 섹션의 인접한 구조화 표면 또는 비구조화 표면으로 형성되는, 구조물을 갖는 금속 시트로 만들어지고, 금속 시트는 접어져서, 서로 일체로 연결된 섹션들이 서로의 상부에 표면 평행 방식으로 배치되게 한다. 금속 시트는 윤곽 엣지를 갖는 적어도 하나의 제3 섹션을 더 포함하고, 또한, 접어져서, 제3 섹션이 표면 평행 방식으로 지지되기도 하고, 윤곽 엣지가 제1 벽 섹션을 형성하며, 제1 섹션 또는 제2 섹션의 인접한 구조화 표면 또는 비구조화 표면은 개방된 유체 라인의 제2 벽 섹션을 형성하게 한다. 이 발명은 또한, 복수의 그러한 미소 유체 컴포넌트를 포함하는 미소 유체 반응기, 및 그러한 컴포넌트들을 생산하는 방법에 관한 것이기도 하다. The present invention relates to a microfluidic component comprising a closed fluid line and comprising a structured surface of a first section of a metal sheet and an adjacent structured or unstructured surface of a second section of the metal sheet, And the metal sheet is folded so that the sections integrally connected to each other are arranged in a surface parallel manner on top of each other. The metal sheet further comprises at least one third section having a contoured edge and is also folded such that the third section is supported in a surface parallel manner and the contour edge forms a first wall section, The adjacent structured or unstructured surface of the second section forms a second wall section of the open fluid line. The invention also relates to a microfluidic reactor comprising a plurality of such microfluidic components, and to a method of producing such components.

REACTOR SYSTEM FOR PRODUCING HYDROCARBONS FROM SYNTHETIC GAS

The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.

MICROCHANNEL REACTORS AND FABRICATION PROCESSES

Welded microchannel processor

This invention relates to an apparatus, comprising: a plurality of plates in a stack defining at least one process layer and at least one heat exchange layer, each plate having a peripheral edge, the peripheral edge of each plate being welded to the peripheral edge of the next adjacent plate to provide a perimeter seal for the stack, the ratio of the average surface area of each of the adjacent plates to the average penetration of the weld between the adjacent plates being at least about 100 cm2/mm. The stack may be used as the core assembly for a microchannel processor. The microchannel processor may be used for conducting one or more unit operations, including chemical reactions such as SMR reactions.

A laminated microchannel assembly, and a method of forming the laminated microchannel assembly by welding

Reactor system for producing hydrocarbons from synthetic gas

The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.

HEAT EXCHANGER

A heat exchanger (800), comprising:a first channel (810) having a flowpath, a first wall (805), a second wall (832) opposite the first wall, an inlet manifold (812) at a first end, and an outlet manifold (814) at a second opposite end, the inlet manifold and the outlet manifold running orthogonal to the flowpath; a second channel (820) having a flowpath parallel to the flowpath of the first channel, the first channel and the second channel being separated by the first wall; and a fin extending from the second channel into the first channel, the fin passing through the first wall and extending to the second wall..

REACTOR SYSTEM FOR PRODUCING HYDROCARBONS FROM SYNTHETIC GAS

The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.

Microfluidic component, reactor comprising a plurality of such components, and method for producing same

A microfluidic component made of a metal sheet having a structure which includes a closed fluid line and which is formed of a structured surface of a first section of the metal sheet and an adjoining structured or unstructured surface of a second section of the metal sheet, wherein the metal sheet is folded such that the sections integrally connected to each other are located on top of each other in a surface-parallel manner. The metal sheet further includes at least one third section having a contoured edge and is moreover folded such that the third section is also supported in a surface-parallel manner and the contoured edge forms a first wall section and the adjoining structured or unstructured surface of the first or second section forms a second wall section of an open fluid line. A microfluidic reactor comprising a plurality of such microfluidic components and a method for producing such components.

Modular flow reactor

A modular flow reactor is formed of a plurality of modules, wherein each module comprises a body having at least one conduit passing therethrough, and wherein a plurality of said modules are aligned along a longitudinal axis such that said conduits of said modules are aligned to form a passage for fluid, wherein each module has a length along said longitudinal axis which is less than the length of the module perpendicular to the longitudinal axis. The modules are “slices” rather than “tubes” and a plurality of said modules can be aligned linearly so that the conduits form a tube.

MICROCHANNEL REACTORS AND FABRICATION PROCESSES

A method of loading material within a microchannel device, the method comprising: (a) loading particulates into a plurality of microchannels; and, (b) ultrasonically packing the particulates into the plurality of microchannels using a portable, compact ultrasonic densification unit. 135-. (canceled)36. A method of increasing packing density of particulates loaded into a plurality of microchannels in microchannel apparatus , comprising: providing a microchannel apparatus comprising a plurality of microchannels having particulates contained therein; mounting a portable , compact ultrasonic device to a microchannel apparatus , the portable , compact ultrasonic device configured to be repositionable between a first position where the portable , compact ultrasonic device is in acoustic communication with the plurality of microchannels and a second position where the portable , compact ultrasonic device is not in acoustic communication with the plurality of microchannels; and , applying ultrasonic sound to the plurality of microchannels from the portable , compact ultrasonic device to densify the particulates to form a packed bed of particulates within the plurality of microchannels.37. The method of claim 36 , wherein a sonically conductive material is disposed between the portable claim 36 , compact ultrasonic device and the plurality of microchannels.3841-. (canceled)42. The method of claim 36 , wherein the ultrasonic sound is applied in bursts of one to ten seconds.43. The method of claim 36 , wherein each microchannel in the plurality of microchannels has a length of at least 10 cm and at least one dimension of 10 mm or less.44. The method of claim 36 , wherein the microchannel apparatus comprises at least 1000 microchannels and wherein the portable claim 36 , compact ultrasonic device extends over no more than 500 of the at least 1000 microchannels at one time.45. The method of claim 36 , wherein: the microchannel apparatus comprises an insert that extends down the ...

REACTOR INCORPORATING A HEAT EXCHANGER

A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath. 1. A heat exchanger , comprising:a first channel having a flowpath, a first wall, a second wall opposite the first wall, an inlet manifold at a first end, and an outlet manifold at a second opposite end, the inlet manifold and the outlet manifold running orthogonal to the flowpath;a second channel having a flowpath parallel to the flowpath of the first channel, the first channel and the second channel being separated by the first wall; anda fin extending from the second channel into the first channel, the fin passing through the first wall and extending to the second wall;wherein the heat exchanger is formed from a channel shim and a separator shim, wherein the channel shim defines the first channel, and wherein the separator shim includes the fin; andwherein the channel shim and the separator shim cooperate to form the first wall.2. The heat exchanger of claim 1 , wherein the first channel has a plurality of micro-channels and the second channel has a plurality of micro-channels 0.3. The heat exchanger of claim 2 , wherein the ratio of a first micro-channel width to a first micro-channel height is from 2:1 to 20:1.4. The heat exchanger of claim 1 , wherein the ratio of a channel shim height to ...

Reactor incorporating a heat exchanger

A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath.

REACTOR INCORPORATING A HEAT EXCHANGER

A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath. 1. A heat exchanger , comprising:a first channel having a flowpath, a first wall, a second wall opposite the first wall, an inlet manifold at a first end, and an outlet manifold at a second opposite end, the inlet manifold and the outlet manifold running orthogonal to the flowpath, and a mixing manifold within the first channel running orthogonal to the flowpath, wherein the first channel comprises a plurality of first micro-channels and the mixing manifold permits vertical mixing between first micro-channels; anda second channel having a flowpath parallel to the flowpath of the first channel, the first channel and the second channel being separated by the first wall.2. The heat exchanger of claim 1 , further comprising a fin extending from the second channel into the first channel claim 1 , the fin passing through the first wall and extending to the second wall;3. The heat exchanger of claim 1 , wherein the ratio of a first micro-channel width to a first micro-channel height is from 2:1 to 20:1.4. The heat exchanger of claim 1 , wherein the second channel comprises a plurality of second micro-channels.5. The heat exchanger of claim 1 , wherein the heat exchanger is formed from a channel shim ...

LAMINATED, LEAK-RESISTANT CHEMICAL PROCESSORS, METHODS OF MAKING, AND METHODS OF OPERATING

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described. 121-. (canceled)22. A pressure-resistant substrate assembly , comprising:a welded laminate configured such that, during operation, flow of fluids through the laminate is primarily perpendicular to sheet thickness;wherein the laminate comprises a first layer adjacent to a second layer and a periphery around the first and second layers;wherein the periphery is perpendicular to sheet thickness;wherein the first layer comprises microchannels and wherein the second layer comprises channels and seals along the periphery, wherein the seals hold a differential pressure of more than 100 psig between the first layer and the second layer; andwherein the seals are not diffusion bonded or brazed.23. The pressure-resistant substrate assembly of wherein the seals hold a differential pressure of more than 500 psig between the first layer and the second layer.24. A welded pressure-resistant substrate assembly claim 22 , comprising:a plurality of channels that are sealed welding;wherein the sealing is not the result of polymeric gaskets, brazing, or diffusion bonding;and having a leak rate of less than 10 sccm nitrogen when pressurized with nitrogen gas at 100 psig and room temperature.25. The welded pressure-resistant substrate assembly of having a leak rate of less than 11 sccm nitrogen when pressurized with nitrogen gas at 100 psig and room temperature.25. The welded pressure-resistant substrate assembly of wherein the assembly comprises a plurality of sheets in a stack claim 24 , ...

A glass lined metal micro-reactor

The invention discloses a glass lined metal micro-reactor with enhanced heat transfer efficiency in continuous flow operation. More particularly, the invention discloses a glass lined micro-reactor that can be reassembled. The invention provides a novel glass lined metal micro-reactor with micro fluidic channels that provide a better mixing, better heat exchange, and better temperature control. The micro fluidic channels machined in the glass lined metal reactor/mixer may be straight, curved, lamellar, flower shaped, or spiral such that the cross sectional area of the micro fluidic channel is configured to suit the cross sectional area of the micro-reactor.

SYNTHESIS GAS CONVERSION PROCESS

The disclosed invention relates to a method for restarting a synthesis gas conversion process which has stopped. The synthesis gas conversion process may be conducted in a conventional reactor or a microchannel reactor. The synthesis gas conversion process may comprise a process for converting synthesis gas to methane, methanol or dimethyl ether. The synthesis gas conversion process may be a Fischer-Tropsch process. 123-. (canceled)24. A method for restarting a synthesis gas conversion process , wherein the synthesis gas conversion process comprises flowing synthesis gas into a reactor in contact with a synthesis gas conversion catalyst at a desired reaction temperature and pressure to produce a synthesis gas conversion product and flowing effluent comprising the synthesis gas conversion product out of the reactor , the method comprising:(A) stopping the flow of synthesis gas into the reactor;(B) flowing natural gas into the reactor to purge the reactor; and(C) restarting the flow of synthesis gas into the reactor.25. The method of wherein the synthesis gas comprises CO and prior to stopping the flow of synthesis gas into the reactor the conversion of CO is at a desired conversion value claim 24 , and after restarting the flow of synthesis gas into the reactor the conversion of CO at the desired conversion value is achieved within a time period of up to about 3 hours.2629-. (canceled)30. The method of wherein the reactor comprises a fixed bed reactor claim 24 , a fluidized bed reactor or a slurry phase reactor.31. The method of wherein the reactor comprises a conventional reactor.32. The method of wherein the reactor comprises a microchannel reactor.33. The method of wherein the synthesis gas conversion process comprises a process for converting synthesis gas to methane.34. The method of wherein the synthesis gas conversion process comprises a process for converting synthesis gas to methanol or dimethyl ether.35. The method of wherein the synthesis gas conversion ...

Synthesis gas conversion process

The disclosed invention relates to a method for restarting a synthesis gas conversion process which has stopped. The synthesis gas conversion process may be conducted in a conventional reactor or a microchannel reactor. The synthesis gas conversion process may comprise a process for converting synthesis gas to methane, methanol or dimethyl ether. The synthesis gas conversion process may be a Fischer-Tropsch process.

SYNTHESIS GAS CONVERSION PROCESS

The disclosed invention relates to a method for restarting a synthesis gas conversion process which has stopped. The synthesis gas conversion process may be conducted in a conventional reactor or a microchannel reactor. The synthesis gas conversion process may comprise a process for converting synthesis gas to methane, methanol or dimethyl ether. The synthesis gas conversion process may be a Fischer-Tropsch process. 1102-. (canceled)103. A method for restarting a synthesis gas conversion process , wherein the synthesis gas conversion process comprises flowing synthesis gas into a reactor in contact with a synthesis gas conversion catalyst at a desired reaction temperature and pressure to produce a synthesis gas product and flowing effluent comprising the synthesis gas conversion product out of the reactor , the method comprising:(A) stopping the flow of the synthesis gas into the reactor;(B) flowing hydrogen or natural gas into the reactor to purge the reactor; and(C) restarting the flow of synthesis gas into the reactor.104. The method of wherein the reactor is a conventional reactor.105. The method of wherein the reactor is a microchannel reactor.106. The method of wherein prior to step (A) the pressure within the reactor is at a pre-stoppage pressure claim 103 , and during step (A) the pressure within the reactor is reduced to a level lower than the pre-stoppage pressure claim 103 , and prior to step (B) the pressure within the reactor is increased to the pre-stoppage pressure.107. The method of wherein the catalyst is rejuvenated using hydrogen during step (B).108. The method of wherein during step (B) hydrogen flows into the reactor in contact with the catalyst at a temperature of up to 400° C. claim 103 , then air flows into the reactor in contact with the catalyst at a temperature in the range from 70° C. to 350° C. for a period of time in the range from 1 to 24 hours claim 103 , then hydrogen flows into the reactor in contact with the catalyst at a ...

SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product. 129-. (canceled)30. A method for producing chemical products , comprising:transporting a first fluid comprising a first chemical reactant through a first module comprising a chemical reactor and at least a second unit operation fluidically connected in parallel, and through a second module connected to the first module in series, the second module comprising at least one separator and at least a fourth unit operation fluidically connected in parallel, such that the first chemical reactant within the first fluid is reacted to form a first chemical product that is transported out of the second module; andsubsequently, transporting a second fluid comprising a second chemical reactant through the first module and the second module such that the second chemical reactant within the second fluid is reacted to form a second chemical product, without forming the first chemical product, such that the second chemical product is transported out of the second module; no additional unit operations are newly fluidically connected to the first and second modules between the steps of transporting the first fluid and transporting the second fluid, and', 'no unit operations are fluidically disconnected from the first and second modules between the steps of transporting the first fluid and transporting the second fluid., 'wherein31. The method of claim 30 , wherein transporting the first fluid through the separator comprises separating the first fluid into a first stream containing the first chemical product and a second stream containing a first chemical byproduct.32. The method of claim 30 , wherein the first and/ ...

Heat exchange reactor and method for producing the same

본 발명은 열교환 반응기 및 이의 제조방법에 관한 것으로, 길이방향을 따라 평행하게 형성되는 복수의 슬릿을 구비하는 측면판을 준비하는 단계; 2개의 측면판을 수직방향으로 마주보도록 이격 배치하는 단계; 두 측면판의 적어도 하나 이상의 슬릿에 유로 격판을 수평방향으로 평행하게 끼워 복수의 유로 채널을 형성하는 단계; 자체적으로 내부에 적어도 하나 이상의 열교환 유로를 포함하는 인쇄회로형 열교환판을, 두 측면판의 적어도 하나 이상의 슬릿에 수평방향으로 평행하게 끼워 복수의 유로 채널을 형성하는 단계; 및 측면판, 유로 격판 및 인쇄회로형 열교환판을 각각 접합하는 단계를 포함하는 열교환 반응기의 제조방법을 제공한다. The present invention relates to a heat exchange reactor and a method of manufacturing the same, comprising the steps of: preparing a side plate having a plurality of slits formed in parallel along a longitudinal direction; Disposing the two side plates so as to face each other in the vertical direction; Forming a plurality of flow channel channels by horizontally inserting the flow channel plates in at least one slit of the two side plates in parallel; Forming a plurality of flow channel channels by horizontally inserting a printed circuit type heat exchange plate including at least one heat exchange channel therein in parallel in at least one slit of the two side plates; And a step of bonding the side plates, the flow path plates and the printed circuit type heat exchange plates, respectively.

Reactor system for producing hydrocarbons from synthetic gas

본 발명은 반응기 벽에 워시 코트한(wash-coated) 다중 채널 반응기의 단점인 촉매 교체의 문제를 해결하고자 열교환부와 반응부가 조립식으로 구조화된 반응장치를 제공하고자, 판상형 혹은 주름(corrugated) 판상형 열교환기가 복수개로 구성된 열교환부를 탈부착이 가능한 형태로 만들어 반응부 내에 삽입할 수 있는 장치를 제공한다. 본 발명에 의하면, 열교환판의 열전달 면에 촉매를 워시 코트(wash coat) 등의 방법으로 부착하여 사용하면, 열전달 효율이 극대화될 뿐만 아니라, 촉매 수명 종료 시 열교환부를 탈착하여, 촉매를 용이하게 제거하거나 다시 부착시킬 수 있는 효과를 가진다. The present invention seeks to provide a reaction apparatus in which the heat exchanger and the reaction unit are prefabricated in order to solve the problem of catalyst replacement, which is a disadvantage of the wash-coated multi-channel reactor on the wall of the reactor, a plate or corrugated plate heat exchanger The present invention provides an apparatus capable of inserting a heat exchanger having a plurality of groups into a detachable form and inserting the same into the reaction unit. According to the present invention, when the catalyst is attached to the heat transfer surface of the heat exchange plate by a wash coat or the like, the heat transfer efficiency is maximized, and the heat exchange part is desorbed at the end of the catalyst life, thereby easily removing the catalyst. It has the effect of attaching or reattaching.

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

활성 제약 성분을 포함한 화학적 생성물의 합성을 위한 시스템 및 방법이 제공된다. 본원에 기재된 특정 시스템 및 방법은, 어느 한 화학적 생성물의 제조로부터 또 다른 화학적 생성물의 제조로 스위칭할 때 유닛 작동들을 유체 연결 또는 차단할 필요 없이 여러 화학적 생성물을 제조할 수 있다.

Reactor system for producing hydrocarbons from synthetic gas

本发明涉及一种反应器系统,包括装配在一起并在一个结构内的热交换单元和反应单元。所述热交换单元具有多个平板或波形板热交换器，并且设置为可附着于所述反应单元/可从所述反应单元上拆卸，以及可插入到所述反应单元中。相应地，催化剂可通过洗涂法等附着在所述热交换器的热传递表面，从而最大化热传递效率并且使得在催化剂使用寿命终结时能容易地去除或重新附着该催化剂。

Method for stopping and restarting a Fischer-Tropsch process

The disclosed invention relates to a method for restarting a synthesis gas conversion process which has stopped. The synthesis gas conversion process may be conducted in a conventional reactor or a microchannel reactor. The synthesis gas conversion process may comprise a process for converting synthesis gas to methane, methanol or dimethyl ether. The synthesis gas conversion process may be a Fischer-Tropsch process.

Synthesis gas conversion process

The disclosed invention relates to a method for restarting a synthesis gas conversion process which has stopped. The synthesis gas conversion process may be conducted in a conventional reactor or a microchannel reactor. The synthesis gas conversion process may comprise a process for converting synthesis gas to methane, methanol or dimethyl ether. The synthesis gas conversion process may be a Fischer-Tropsch process.

Microfluidic double-water-phase cocurrent laminar flow enzymatic reaction technique

本发明公开了一种微流控双水相平行层流酶促反应技术。本发明以双水相两相溶液为载体，在双Y形微流控装置中进行酶促反应分离，用注射泵为流体提供流动动力，用注射器针头和玻璃片制作微型装置，构建双水相平行层流传质界面，使酶催化反应能够快速连续的进行并使产物分离纯化。且装置具有结构简单，制作方便等优点。该技术分离效果优于传统的分批次双水相生物反应，且操作过程连续、能耗低，层流界面操控灵活、可连续循环使用酶液以节约成本。本发明利用微尺度双水相层流界面强化了相间传质、酶促反应和分离，在原材料昂贵、产品附加值高的生物反应分离领域具有广阔的应用前景。

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

활성 제약 성분을 포함한 화학적 생성물의 합성을 위한 시스템 및 방법이 제공된다. 본원에 기재된 특정 시스템 및 방법은, 어느 한 화학적 생성물의 제조로부터 또 다른 화학적 생성물의 제조로 스위칭할 때 유닛 작동들을 유체 연결 또는 차단할 필요 없이 여러 화학적 생성물을 제조할 수 있다.

Laminated, leak-resistant chemical processors, methods of making, and methods of operating

본 발명은 판들을 함께 조립되어 용접된 라미네이트형 장치(특히, 마이크로채널 장치)의 제조 방법을 제공한다. 종래의 마이크로채널 장치와 달리, 본 발명의 라미네이트형 장치는 브레이징 또는 확산 접합없이 수행될 수 있어 제조 시 현저한 이점을 제공할 수 있다. 또한, 팽창 접합 및 외부 용접 지지부와 같은 특징도 설명한다. 또한, 라미네이트형 장치와 라미네이트형 장치에서의 유닛 조작 수행 방법도 설명한다. The present invention provides a method of manufacturing a laminated device (particularly a microchannel device) welded together by plates. Unlike a conventional microchannel device, the laminated device of the present invention can be performed without brazing or diffusion bonding, which can provide significant advantages in manufacturing. Features such as expansion joints and external weld supports are also described. A method of carrying out a unit operation in a laminated type apparatus and a laminated type apparatus is also described.

It is laminated leakproof chemical processor, production method and operating method

本发明提供制作层压装置(特别是微通道装置)的方法，其中板被组装并焊接在一起。与常规微通道装置不同，本发明的层压装置可在无钎焊或扩散结合的情况下制作；从而为制造提供明显的优势。还描述了如膨胀接头和外部焊接支撑件等特征。还描述了层压装置以及在层压装置中进行单元操作的方法。

Microchannel processor

本发明涉及一种装置，其包括：多个位于堆中的平板，所述平板限定出至少一个工艺层和至少一个热交换层，每个平板均具有外周边缘，每个平板的外周边缘被焊接至下一个相邻平板的外周边缘，以为所述堆提供外周密封，所述相邻平板中的每个平板的平均表面积与所述相邻平板之间的焊接的平均熔深的比值至少为大约100cm 2 /mm。所述堆可以被用作微通道处理器的核心组件。所述微通道处理器可以被用于实施一个或多个单元操作，所述单元操作包括化学反应，例如SMR反应。

Fluid modules suspension and the reactor obtained

一种模块化反应器（10）包括被设置在方向D上延伸的间隔的水平延伸行中的多个平面流体模块（12），模块（12）的主要表面（14、16）大体平行于彼此定向。多个刚性或半刚性的流体连接器（30）各自被放置在模块的面向的主表面（14、16）之间，并且该流体连接器（30）将面向的表面的第一表面（24）上的至少一个流体端口（18a）流体且机械地接合到面向的表面（14、16）的第二表面（26）上的至少一个其他流体端口（18b）。该反应器（10）进一步包括水平延伸的支撑结构（60）和一个或多个悬杆（32），该支撑结构（60）在方向D上、在模块（12）的行的上方延伸，并且悬杆（32）各自从支撑结构（60）支撑多个流体模块（12）中的一个。该悬杆（32）包括具有第一轴线（36）的第一旋转接头（34），该第一轴线（36）被放置在各自模块（12）上方和支撑结构（60）的下方，并且选择性并期望地包括具有第二轴线（40）的第二旋转接头（38），这一个或两个轴线（36、40）与方向D垂直。

Reactor assemblies and methods of performing reactions

Reactors are provided that can include a first set of fluid channels and a second set of fluid channels oriented in thermal contact with the first set of fluid channels, either one or both of the first of the set of fluid channels are non-linear. Reactor assemblies can include a first set of fluid channels defining at least one non-linear channel having a positive function, and a second set of fluid channels defining at least another non-linear channel having a negative function in relation to the positive function of the one non-linear channel of the first set of fluid channels. Processes for distributing energy across a reactor are provided. Transporting reactants via a first set of fluid channels to a second set of fluid channels, and thermally engaging at least one of the first set of fluid channels with at least two of the second set of fluid channels.

Microreactor for photocatalytic reactions

本发明涉及一种用于物质的光催化还原的装置，该装置具有结构化反应板和/或结构化壳体，其中，反应板至少在某些区域具有包括负电子亲和势的材料的表面，并且该表面能够用波长≥180nm的辐射进行电子激发。

Reactor system for producing hydrocarbons from synthetic gas

The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.

Reactor incorporating a heat exchanger

A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath.

Laminate Leak Resistant Chemical Processors, Manufacturing Methods and Operating Methods

procesadores químicos resistentes ao vazamento laminados, métodos de fabricação e métodos de operação. a invenção fornece os métodos de fabricar dispositivos laminados (especialmente dispositivos de microcanal) em que as placas são montadas e soldadas juntas. diferente dos dispositivos convencionais de micro-canal, os dispositivos inventivos laminados podem ser feitos sem brasagem ou aglutinação por difusão; dessa forma, fornecendo vantagens significativas para fabricação. os recursos, tais como, articulações de expansão e suportes soldados externos, também são descritos. os dispositivos laminados e métodos de conduzir operações de unidade nos dispositivos laminados também são descritos. Laminate-resistant chemical processors, manufacturing methods and operating methods. The invention provides methods of manufacturing laminated devices (especially microchannel devices) wherein the plates are assembled and welded together. unlike conventional micro-channel devices, inventive laminated devices may be made without brazing or diffusion bonding; thereby providing significant advantages for manufacturing. features such as expansion joints and external welded brackets are also described. laminate devices and methods of conducting unit operations on laminate devices are also described.

Modular microplasma microchannel reactor devices, miniature reactor modules and ozone generation devices

A preferred modular microplasma microchannel reactor device includes a microchannel array arranged with respect to electrodes for generation of plasma and isolated by dielectric from the electrodes. A cover covers a central portion of the microchannel array, while leaving end portions of the microchannel array exposed. A gas inlet and product outlet are arranged to permit flow into, through and out of the microchannel array. Reactor modules of the invention include pluralities of the modular reactor devices. The reactors devices can be arranged by a housing or a frame to be in fluid communication. A system of the invention arranges pluralities of modules. Preferred module housings, frames and reactors include structural features to create alignments and connections. Preferred modules include fans to circulate feedstock and reaction product. Other reactor devices provide plasma actuation for flow.

Micro-fluidic device

The present invention relates to a micro-fluidic device comprising a process channel having a top wall, a bottom wall and side walls, the process channel having a height between 0.2 mm and 3 mm, a width between 1.0 and 50 mm and support means within said process channel. The support means extends between the bottom wall and the top wall of the process channel in a direction substantially perpendicularly to the top wall. The micro-fluidic device comprises at least one heat exchange means parallel to the process channel and optionally comprises a static mixing element. The present invention further relates to a kit of parts and a micro-fluidic system comprising such micro-fluidic devices.

Microstructure and method of producing the same

Fluid connector devices and methods of making and using the same

A fluid connector device (10) is provided. The fluid connector device includes a coupling substrate (12) having a conformal recess (20), a reconnectable fitting (18) disposed in the recess to provide a first passageway, and a force applying element (16) operatively coupled to the reconnectable fitting (18), or the coupling substrate (12), or both the reconnectable fitting (18) and the coupling substrate (12) to at least partially provide a sealing force between the reconnectable fitting (18) and the coupling substrate (12), wherein at least one of the force applying element (16), the reconnectable fitting (18), and the coupling substrate (12) comprises one or more degrees of freedom for self alignment of the reconnectable fitting (18) and the conformal recess (12).

Catalytic reactor and a method for producing the same

Ein katalytischer Reaktor umfasst mehrere röhrenförmigen Elemente 110, die jeweils einen ersten Reaktionskanal K1 in ihrem Innenraum bereitstellen, und zumindest einen Abstandshalter 120. Der Abstandshalter 120 ist ausgebildet, um die mehreren röhrenförmigen Elemente 110 in einem Mindestabstand voneinander zu halten. Die mehreren röhrenförmigen Elemente 110 weisen eine katalytische Beschichtung 130 auf, um eine chemische Reaktion in den ersten Reaktionskanälen K1 und/oder in dem zweiten Reaktionskanal K2 zu fördern. A catalytic reactor includes a plurality of tubular members 110, each providing a first reaction channel K1 in its interior, and at least one spacer 120. The spacer 120 is configured to keep the plurality of tubular members 110 a minimum distance apart. The plurality of tubular elements 110 have a catalytic coating 130 to promote a chemical reaction in the first reaction channels K1 and / or in the second reaction channel K2.

A glass lined metal micro-reactor

The invention discloses a glass lined metal micro-reactor with enhanced heat transfer efficiency in continuous flow operation. More particularly, the invention discloses a glass lined micro-reactor that can be reassembled. The invention provides a novel glass lined metal micro-reactor with micro fluidic channels that provide a better mixing, better heat exchange, and better temperature control. The micro fluidic channels machined in the glass lined metal reactor/mixer may be straight, curved, lamellar, flower shaped, or spiral such that the cross sectional area of the micro fluidic channel is configured to suit the cross sectional area of the micro-reactor.

Photoreaction micro reactor

有効医薬品原料を含む化学生成物を合成するためのシステムおよび方法

【課題】有効医薬品原料を含む、化学生成物を合成するためのシステムおよび方法を提供すること【解決手段】有効医薬品原料を含む、化学生成物を合成するためのシステムおよび方法が、提供される。本明細書に説明されるシステムおよび方法のあるものは、ある化学生成物の作製から別の化学生成物の作製に切り替えるとき、ユニット動作を流体的に接続または切断する必要なく、複数の化学生成物を製造可能である。本発明の主題は、ある場合には、相互関連生成物、特定の問題の代替解決策、および／または１つまたはそれを上回るシステムおよび／または物品の複数の異なる使用を伴う。【選択図】なし

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to 5 fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

A modular flow reactor

A modular flow reactor is formed of a plurality of modules, wherein each module comprises a body having at least one conduit passing therethrough, and wherein a plurality of said modules are aligned along a longitudinal axis such that said conduits of said modules are aligned to form a passage for fluid, wherein each module has a length along said longitudinal axis which is less than the length of the module perpendicular to the longitudinal axis. The modules are "slices" rather than "tubes" and a plurality of said modules can be aligned linearly so that the conduits form a tube.

Plate-type heat exchanger reactor and method for producing the same

The present invention relates to a plate-type heat exchange reactor and a method of manufacturing thereof, and there is provided a method of manufacturing a plate-type heat exchange reactor and a plate-type heat exchange reactor manufactured in the manufacturing method, the method including the steps of preparing side surface plates respectively provided with a plurality of slits formed in parallel along a longitudinal direction; arranging two side surface plates in a vertical direction to face each other with a space therebetween; forming a plurality of fluid passage channels by inserting a plurality of fluid passage partition walls into the slits provided on the two side surface plates in parallel in a horizontal direction; and bonding the side surface plates and the fluid passage partition walls.

使用微通道加热器的烃重整装置

本发明涉及一种使用微通道加热器的烃重整装置，其中，利用燃料的燃烧热作为烃重整反应所需的能量来源。所述烃重整装置通过层压具有微通道的薄金属板形成多层结构，因此，所述烃重整装置适合用于小型和中型的紧凑型氢气生产装置。特别地，由于在使用分离膜的氢气再生方法中，不被分离膜过滤的含氢气的气体可以作为燃料使用，因此，所述烃重整装置可以被用作高效的氢气生产系统。

Microreactor for photoreactions

A microreactor for photoreactions includes a housing upper part, a lid plate made of a material that allows transmission of light, a flow path plate made of a material that suppresses light reflection and has a high thermal conductivity, and a housing lower part. Light is applied through a window of the housing upper part and the lid plate to a flow path of the flow path plate. The lid plate made of the material that allows transmission of light and the flow path plate made of the material that suppresses light reflection and has a high thermal conductivity are welded each other to form an integrated body.

光反応マイクロリアクタ

光反応マイクロリアクタ（１０１）は、ハウジング上部（１０２）と、光を透過する材質からなるフタプレート（１０３）と、光の反射を抑制し、かつ熱伝導性の高い材質からなる流路プレート（１０４）と、ハウジング下部（１０５）とを備える。ハウジング上部（１０２）の窓部及びフタプレート（１０３）を介して光が流路プレート（１０４）の流路（１０９）に光が照射される。光を透過する材質からなるフタプレート（１０３）と、光の反射を抑制し、かつ熱伝導性の高い材質からなる流路プレート（１０４）とは、溶着され互いに一体となっている。

Reactor assemblies and methods of performing reactions

Reactors are provided that can include a first set of fluid channels and a second set of fluid channels oriented in thermal contact with the first set of fluid channels. The reactor assemblies can also provide where the channels of either one or both of the first of the set of fluid channels are non-linear. Other implementations provide for at least one of the first set of fluid channels being in thermal contact with a plurality of other channels of the second set of fluid channels. Reactor assemblies are also provided that can include a first set of fluid channels defining at least one non-linear channel having a positive function, and a second set of fluid channels defining at least another non-linear channel having a negative function in relation to the positive function of the one non-linear channel of the first set of fluid channels. Processes for distributing energy across a reactor are provided. The processes can include transporting reactants via a first set of fluid channels to a second set of fluid channels, and thermally engaging at least one of the first set of fluid channels with at least two of the second set of fluid channels.

평판형 열교환 반응기 및 이의 제조방법

본 발명은 평판형 열교환 반응기 및 이의 제조방법에 관한 것으로, 길이방향을 따라 평행하게 형성되는 복수의 슬릿을 구비하는 측면판을 준비하는 단계; 2개의 측면판을 수직방향으로 마주보도록 이격 배치하는 단계; 두 측면판의 각 슬릿에 복수의 유로 격판을 수평방향으로 평행하게 끼워 복수의 유로 채널을 형성하는 단계; 및 측면판과 유로 격판을 접합하는 단계를 포함하는 평판형 열교환 반응기의 제조방법 그리고 이 제조방법에 제조되는 평판형 열교환 반응기를 제공한다.

Synthesis gas conversion process

A method for restarting a synthesis gas conversion process is provided. The process comprises flowing synthesis gas into a microchannel reactor in contact with a synthesis gas conversion catalyst at a desired reaction temperature and pressure to produce a synthesis gas conversion product and flowing effluent comprising the gas conversion product out of the reactor. The method comprises stopping the flow of synthesis gas into the reactor and the flow of effluent out of the reactor for a period of time of up to 48 hours or from 0.1 hours to 48 hours; flowing nitrogen gas into the reactor to purge the reactor and restarting the flow of effluent out of the reactor; and restarting the flow of the synthesis gas into the reactor.

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

微结构件及其制造方法

本发明涉及引导流体的微结构件及其制造方法，引导金属板经过型材轧辊对的之间的辊缝并借此使其微结构化，在宽度方向形成波纹形轮廓；从微结构化的金属板以一定长度切割出微结构化的板；在未结构化的板上施加焊剂；微结构化的板和未结构化的板被组装成一个堆叠件，该堆叠件借助真空焊连接。微结构件具有交替堆叠的微结构化的板和未结构化的板，其中该微结构化的板在宽度方向具有波纹形轮廓，该波纹形轮廓总是在顶点区域具有槽形凹处，其中在该顶点区域存在微结构化的板和未结构化的板之间的钎焊连接，并且焊剂填充所述槽形凹处，在板之间形成多个流体通道，每个流体通道在周向上由微结构化的板的第一表面和未结构化的板的第二表面界定。

활성 제약 성분을 포함한 화학적 생성물의 합성을 위한 시스템 및 방법

활성 제약 성분을 포함한 화학적 생성물의 합성을 위한 시스템 및 방법이 제공된다. 본원에 기재된 특정 시스템 및 방법은, 어느 한 화학적 생성물의 제조로부터 또 다른 화학적 생성물의 제조로 스위칭할 때 유닛 작동들을 유체 연결 또는 차단할 필요 없이 여러 화학적 생성물을 제조할 수 있다.

反应器组件和执行反应的方法

本发明提供了反应器，其可以包括第一组流体通道和被定向成与第一组流体通道热接触的第二组流体通道。还可以提供反应器组件，其中第一组流体通道或第二组流体通道中的任一组或两组的通道都是非线性的。其他实施方式提供了第一组流体通道中的至少一个流体通道与第二组流体通道中的多个其他通道热接触。还提供了反应器组件，其可包括：限定至少一个非线性通道的第一组流体通道，所述至少一个非线性通道具有正函数；以及限定至少另一个非线性通道的第二组流体通道，所述至少另一个非线性通道具有相对于第一组流体通道的一个非线性通道的正函数的负函数。提供了用于在反应器上分配能量的方法。所述方法可包括经由第一组流体通道将反应物输送到第二组流体通道，并且使第一组流体通道中的至少一个流体通道与第二组流体通道中的至少两个流体通道热接合。

用于微通道反应器的分布板及具有其的微通道反应器

本发明涉及一种用于微通道反应器的分布板，包括多个拼接板体、密封条以及压紧板条，相邻的两个拼接板体之间留有安置槽，密封条设于上述安置槽中，压紧板条的横截面大致呈T型，并具有作为两侧水平部位的横向压紧部以及作为中央竖向部位的竖向压紧部，压紧板条的竖向压紧部能嵌入安置槽中，将密封条压紧在所述的反应板组件上，并由可拆卸紧固件与对应的反应板组件锁紧在一起，压紧板条的横向压紧部对应压紧在位于安置槽的两侧的两个拼接板体上。该分布板不受反应器大小以及反应器壳体的进出口端口大小的限制，拆装简单方便，可操作性强，且能重复利用。本发明还涉及一种具有上述分布板的微通道反应器。

用于光催化反应的微反应器

本发明涉及一种用于物质的光催化还原的装置，该装置具有结构化反应板和/或结构化壳体，其中，反应板至少在某些区域具有包括负电子亲和势的材料的表面，并且该表面能够用波长≥180nm的辐射进行电子激发。

Glass lined metal micro-reactor

The invention discloses a glass lined metal micro-reactor with enhanced heat transfer efficiency in continuous flow operation. More particularly, the invention discloses a glass lined micro-reactor that can be reassembled. The invention provides a novel glass lined metal micro-reactor with micro fluidic channels that provide a better mixing, better heat exchange, and better temperature control. The micro fluidic channels machined in the glass lined metal reactor/mixer may be straight, curved, lamellar, flower shaped, or spiral such that the cross sectional area of the micro fluidic channel is configured to suit the cross sectional area of the micro-reactor.

Reactor incorporating a heat exchanger

A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath.

Microreactor for photoreactions

A microreactor for photoreactions includes a housing upper part, a lid plate made of a material that allows transmission of light, a flow path plate made of a material that suppresses light reflection and has a high thermal conductivity, and a housing lower part. Light is applied through a window of the housing upper part and the lid plate to a flow path of the flow path plate. The lid plate made of the material that allows transmission of light and the flow path plate made of the material that suppresses light reflection and has a high thermal conductivity are welded each other to form an integrated body.

Heat exchange reactor using thin plate provided with flow path therein and method of manufacturing the same

Disclosed are a heat exchange reactor and a method of manufacturing the same, and a method of manufacturing a heat exchange reactor includes: preparing lateral plates provided with a plurality of slits formed in parallel in a longitudinal direction; disposing two lateral plates to be spaced apart from each other while facing each other in a vertical direction; forming a plurality of flow path channels by inserting flow path partition plates into one or more slits of the two lateral plates in a horizontal direction; forming a plurality of flow path channels by inserting printed circuit heat exchange plates, which autonomously include one or more heat exchange flow paths therein, into one or more slits of the two lateral plates in a horizontal direction; and bonding the lateral plates, the flow path partition plates, and the printed circuit heat exchange plates.

Laminated, leak-resistant chemical processors; methods of making, and methods of operating

The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described.

Fluidic module permanent stack assemblies and methods

The present disclosure provides an assembled stack of fluidic modules comprising at least first and second fluidic modules assembled in a stacked configuration. The first fluidic module has first and second major planar surfaces and encloses a first fluidic passage extending therethrough from a first passage entrance to a first passage exit with the first passage exit located on the second major planar surface of the first fluidic module. The second fluidic module also has first and second major planar surfaces and encloses a second fluidic passage extending therethrough from a second passage entrance to a second passage exit, with the second passage entrance located on the first major planar surface of the second fluidic module. The second major planar surface of the first fluidic module and the first major planar surface of the second fluidic module are spaced apart and physically joined together by at least three separate glass or glass-ceramic pads fused therebetween, and the at least three pads include at least one pad having no through-hole and at least one pad having a through-hole, with the through-hole forming a sealed fluidic interconnection between the first fluidic passage and the second fluidic passage. A method of forming the assembled stack is also disclosed.

Reactor system for producing hydrocarbons from synthetic gas

The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.

Modular flow reactor

A modular flow reactor is formed of a plurality of modules, wherein each module comprises a body having at least one conduit passing therethrough, and wherein a plurality of said modules are aligned along a longitudinal axis such that said conduits of said modules are aligned to form a passage for fluid, wherein each module has a length along said longitudinal axis which is less than the length of the module perpendicular to the longitudinal axis. The modules are “slices” rather than “tubes” and a plurality of said modules can be aligned linearly so that the conduits form a tube.