Поиск патентов

Настройки

Глубина выборки

Укажите год

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Ключевые слова. Может быть несколько по одной на строку

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка

Автор

Ведите корректный номера.

Владелец

Ведите корректный номера.

Классы IPC

Ведите корректный номера.

Классы CPC

Ведите корректный номера.

Начиная с года

Укажите год

Заканчивая годом

Укажите год

Применить Всего найдено 17148. Отображено 100.

16-02-2012 дата публикации

Nozzle assembly for mounting in mechanical or electronic pipette

Номер: US20120039768A1

Автор: Tomasz Strzelczyk

Принадлежит: Pz Htl Sa

The invention relates to a nozzle assembly for mounting in a mechanical or an electronic pipette, which comprises a two-piece body consisting of a nozzle ( 3 ) and a holder ( 2 ), a plunger ( 1 ) cooperating by engaging means with a pipetting rod ( 18 ) of a pipette drawing up and discharging mechanism arranged in a pipette handle ( 16 ), and sealing means for sealing the plunger ( 1 ) in the nozzle assembly. The nozzle ( 3 ) is in its lower part formed respectively for receiving a pipette exchangeable tip ( 19 ) and is in its upper part releasably connected with the holder ( 2 ). In the holder ( 2 ) a pressure sleeve ( 6 ) is placed as being slidably borne in the holder ( 2 ). The pressure sleeve ( 6 ) is via a pressure sub-assembly seated in the holder ( 2 ) pressed to the sealing means placed between the pressure sleeve ( 6 ) and the nozzle ( 3 ). The plunger ( 1 ) is slidably borne in the pressure sleeve ( 6 ) and in the pressure sub-assembly. Due to this, leakproofness of the plunger ( 1 ) in the nozzle ( 3 ), which is indispensable for a correct and reliable pipette operation, is provided in PIPETTING, ADJUSTMENT or CALIBRATION MODES of the pipette. Simultaneously, in MAINTENANCE MODE of the pipette the sealing means automatically slide out from an abutting surface ( 2 c ) of the holder ( 2 ).

Подробнее

Номер записи: 1

16-02-2012 дата публикации

Microreactors With Connectors Sealed Thereon; Their Manufacturing

Номер: US20120040448A1

Автор: Jean-Marc Martin Gerard Jouanno, Olivier Lobet, Ronan Tanguy, Stéphane Poissy, Sylvain Maxime F. Gremetz

Принадлежит: Corning Inc

The present invention deals with microfluidic devices ( 200 ) including a microreactor ( 20 ) and at least one connector ( 101 ) sealed thereon. It also deals with a method for manufacturing such microfluidic devices and to blocks of material suitable as connector.

Подробнее

Номер записи: 2

22-03-2012 дата публикации

Single column immunological test elements

Номер: US20120071345A1

Автор: Mark Sawczuk, Raymond F. Jakubowicz

Принадлежит: Ortho Clinical Diagnostics Inc

A plurality of individual single column test elements are provided for use in a clinical testing apparatus. Each test element is defined by a single test column that includes a quantity of a test material, such as gel material or a bead matrix, including a cover strip used to access the contents of the test column. Individual test elements can be stored, retained and dispensed for testing patient samples.

Подробнее

Номер записи: 3

26-04-2012 дата публикации

Pipette differentiation

Номер: US20120096957A1

Автор: Eitan OCHMAN

Принадлежит: Miniplast Ein Sherner ACAL

A pipette for transferring a volume of liquid, a portion of the pipette formed from a material tinted with a color associated with the pipette volume, facilitating the differentiation of the pipette from other pipettes of different volumes. The portion of the pipette that is tinted may include at least a portion of the pipette top, the pipette body, or the pipette tip. The color tinting may correspond to a color coding standard. The pipette may include additional differentiation characteristics, such as the shape of the pipette, the presence of at least one colored band on the surface of the pipette, the presence of at least one colored material inserted into the pipette top of the pipette, or the presence of a solid colored pipette top.

Подробнее

Номер записи: 4

28-06-2012 дата публикации

Micro-fluidic test apparatus and method

Номер: US20120160019A1

Автор: Christopher F. Perrera, Emmanuel Delamarche, Eric A. Eckberg, Govindarajan Natarajan, James N. Humenik, Kathleen A. McGroddy-Goetz, Marco G. Trivella, Scott Partington, Timothy M. Wiwel

Принадлежит: International Business Machines Corp

An apparatus, system, and method for determining the osmolarity of a fluid. The apparatus includes at least one micro-fluidic circuit and at least one electrical circuit disposed in communication with the micro-fluidic circuit for determining a property of a fluid contained within the at least one micro-fluidic circuit.

Подробнее

Номер записи: 5

28-06-2012 дата публикации

Sample Distribution

Номер: US20120164735A1

Автор: Andreas Gisler, Heinz Trueeb, Paul Frank, Robert Huesler, Rolf Knobel, Siegfried Mueller, Urs Schnieper

Принадлежит: Roche Molecular Systems Inc

A method is described for distributing samples within an automated analyzer from a linear arrangement of sample vessels to a processing plate in a two-dimensional n×m arrangement wherein samples are sorted, followed by transfer with a pipetting device with a linear arrangement to a processing vessel in a two-dimensional n×m arrangement and subsequent processing of samples using a second pipetting device which has a two-dimensional n×m arrangement.

Подробнее

Номер записи: 6

19-07-2012 дата публикации

Laboratory syringe pumps

Номер: US20120183455A1

Автор: Andrew J. Mckenna, Bruce H. Edwards, Justin M. Piccirillo, Mark Davis, Richard K. Bennett, Ron Y. Soslek

Принадлежит: Individual

A syringe pump which includes a pusher block is slidably mounted on bearings on one or more guide rails. The pusher block is advanced or retracted by a lead screw having an axis which is offset from the axis of the one or more guide rails which are supported at their respective ends by support blocks, wherein forward and/or trailing sides of the pusher block bearings are extended, and wherein the guide rail support blocks include recesses for accommodating the extended ends of the pusher block slide bearings. In another embodiment, the syringe pump includes quick connect-disconnect fixtures for loading and unloading syringes. Other mechanical, and programmable improvements are described in the specification.

Подробнее

Номер записи: 7

02-08-2012 дата публикации

Sample liquid supply device, sample liquid supply device set, and microchip set

Номер: US20120195796A1

Автор: Hidetoshi Watanabe

Принадлежит: Sony Corp

A sample liquid supply device includes a container tip into which the sample liquid is introduced, a hollow needle provided at one end of the container tip such that a hollow part thereof communicates with inside of the container tip, and a sealing member that covers an opening from which the sample liquid is introduced, wherein the sealing member has a puncture-sealing property achieved by elastic deformation.

Подробнее

Номер записи: 8

02-08-2012 дата публикации

Apparatus and methods for microfluidic applications

Номер: US20120195809A1

Автор: Douglas Roy, Joel Fearnley, Peter Ghazal, Stuart Polwart

Принадлежит: AGILENT TECHNOLOGIES INC

Non-rigid tape apparatus and fabrication methods for microfluidic processing applications such as gel electrophoresis are provided, where microfluidic processing is performed on selected areas. Parts of the tape are formed by high pressure plastic film forming. Membranes and other structures are self sealing during and after penetration by pipettes and electrical probes. Rigid exoskeleton elements protect the non-rigid parts during processing and facilitate transport of the tape.

Подробнее

Номер записи: 9

09-08-2012 дата публикации

Handle pipette

Номер: US20120198947A1

Автор: Jouko Mikkonen, Juha Telimaa, Mauno Heinonen, Mikael Lind

Принадлежит: THERMO FISHER SCIENTIFIC OY

A handle pipette including at least one cylinder with an upper end and a lower end, said cylinder having a movable piston, an elongate handle ( 1 ), by which the pipette can be manually gripped, said handle having an upper part, and in the upper part of the handle, a sideways extending finger support ( 7 ), which finger support ( 7 ) is at least partly flexible and/or it can be shaped by the user.

Подробнее

Номер записи: 10

30-08-2012 дата публикации

Methods and Microfluidic Devices for the Manipulation of Droplets in High Fidelity Polynucleotide Assembly

Номер: US20120220497A1

Автор: Joseph Jacobson, Larry Li-Yang Chu, Senthil Ramu

Принадлежит: GEN 9 Inc

Methods and devices are provided for manipulating droplets on a support using surface tension properties, moving the droplets along a predetermined path and merging two droplets together enabling a number of chemical reactions. Disclosed are methods for controlling the droplets volumes. Disclosed are methods and devices for synthesizing at least one oligonucleotide having a predefined sequence. Disclosed are methods and devices for synthesizing and/or assembling at least one polynucleotide product having a predefined sequence from a plurality of different oligonucleotides having a predefined sequence. In exemplary embodiments, the methods involve synthesis and/or amplification of different oligonucleotides immobilized on a solid support, release of synthesized/amplified oligonucleotides in solution to form droplets, recognition and removal of error-containing oligonucleotides, moving or combining two droplets to allow hybridization and/or ligation between two different oligonucleotides, and further chain extension reaction following hybridization and/or ligation to hierarchically generate desired length of polynucleotide products.

Подробнее

Номер записи: 11

06-09-2012 дата публикации

Nanopore Device for Reversible Ion and Molecule Sensing or Migration

Номер: US20120222958A1

Автор: Bakthan Singaram, Boaz VILOZNY, Nader Pourmand, Paolo ACTIS, R. Adam Seger

Принадлежит: UNIVERSITY OF CALIFORNIA

Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore.

Подробнее

Номер записи: 12

27-09-2012 дата публикации

Method for leak-testing hand-held piston stroke pipettes and associated leak-testing apparatus

Номер: US20120240663A1

Автор: Rainer Feldmann, Wolfgang Ettig

Принадлежит: Brand GmbH and Co KG

A method for leak testing of hand-held piston stroke pipettes and a corresponding leak testing apparatus ( 1 ) for performing the method. Essential to the system is a holder ( 8 ) for the sealed connection of a pipette tip ( 3 ) to the leak-testing apparatus. A line system ( 9 ) with connecting sections of the leak-testing apparatus forms a specific connection volume. The pipette tip ( 3 ) is evacuated to a measuring pressure below atmospheric pressure. With the vacuum pump ( 5 ) disconnected and the connection volume sealed off, the pressure is measured after a specific time interval, and any possible rise in pressure is determined. An indication of the serviceability of the pipette ( 2 ) is generated from the pressure rise determined.

Подробнее

Номер записи: 13

04-10-2012 дата публикации

Methods and devices for nucleic acid purification

Номер: US20120252115A1

Автор: Chris Suh, Douglas T. Gjerde, Lee Hoang

Принадлежит: Individual

The invention provides pipette tip columns and automated methods for the purification of nucleic acids such as plasmids from unclarified cell lysates containing cell debris as well as methods for making and using such columns. The columns typically include a bed of medium positioned in the pipette tip column, above a bottom frit and with an optional top frit.

Подробнее

Номер записи: 14

11-10-2012 дата публикации

Pipetting device

Номер: US20120258026A1

Автор: Uwe Naumann

Принадлежит: CYBIO AG

The invention relates to a sealing assembly for a metering device, in particular a multi-channel metering device. The sealing assembly serves to seal pipette tips with respect to the metering device. A multi-channel metering device comprises a multiplicity of openings arranged in one plane. A sealing plate with holes in the grid of the openings abuts this plane. Each pipette tip is provided with an annular collar which has an abutting face and is pressed against the sealing plate by force closure so as to enclose one hole.

Подробнее

Номер записи: 15

18-10-2012 дата публикации

Flat Packaging of Petri Dishes for Prolonged Preservation and Method of Producing the Same

Номер: US20120261277A1

Автор: Bret T. Barnhizer

Принадлежит: NanoLogix Inc

The present invention provides an improved flat package of petri dishes and method of producing the same for prolonging shelf life and preservation of sterility of the petri dishes. The flat package is comprised of an optically clear, high-barrier, moisture-, gas- and microbial-resistant pouch. A plurality of petri dishes located adjacent one another are placed in an interior cavity of the pouch, after which the pouch is vacuum-packed, optionally flushed with an inert gas and then heat sealed. The placement and immobilization of the petri dishes in the pouch allow for prolonged shelf life and preservation of sterility, greatly reduced breakage rates, and enhanced visibility of the petri dishes by a user.

Подробнее

Номер записи: 16

01-11-2012 дата публикации

Unit and Device for the Preparation of Cells and/or Particles in a Liquid and Method for Microscopic Analysis

Номер: US20120276575A1

Автор: Christof Fattinger, Dieter Voegelin, René Rietmann

Принадлежит: F Hoffmann La Roche AG

A unit ( 10 ) for the preparation of cells contained in a liquid comprises a storage chamber ( 20 ) configured to store the liquid containing the cells and to release the stored liquid via an exit opening ( 22 ) upon the application of a predetermined external force, in particular a centrifugal force. A passage ( 30 ) adjacently arranged to the exit opening ( 22 ) has a cross-section larger than that of the exit opening ( 22 ). The wall at the transition from the exit opening ( 22 ) to the passage ( 30 ) forms an edge ( 32 ). The unit further comprises an observation member ( 50 ) for receiving the released liquid and an absorbing means ( 40 ) arranged adjacent to the observation member ( 50 ) between the passage ( 30 ) and the observation member ( 50 ). The absorbing means ( 40 ) has an aperture ( 42 ) allowing the released liquid to travel onto the observation member ( 50 ), and removes the liquid so as to leave the cells on the observation member ( 50 ) for observation.

Подробнее

Номер записи: 17

22-11-2012 дата публикации

Systems and methods for valving on a sample processing device

Номер: US20120291565A1

Автор: Jeffrey D. Smith, Peter D. Ludowise

Принадлежит: 3M Innovative Properties Co

A system and method for valving on a sample processing device. The system can include a valve chamber, a process chamber, and a valve septum located between the valve chamber and the process chamber. The system can further include a fluid pathway in fluid communication with an inlet of the valve chamber, wherein the fluid pathway is configured to inhibit a liquid from entering the valve chamber and collecting adjacent the valve septum when the valve septum is in a closed configuration. The method can include rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the valve chamber; forming an opening in the valve septum; and rotating the sample processing device to exert a second force on the liquid to move the liquid into the valve chamber.

Подробнее

Номер записи: 18

22-11-2012 дата публикации

Novel enhanced surface area conico-cylindrical flask (es-ccf) for biofilm cultivation

Номер: US20120295293A1

Автор: Debashis Roy, Joydeep Mukherjee, Sreyashi Sarkar

Принадлежит: Council of Scientific and Industrial Research CSIR

A novel enhanced surface area conico-cylindrical flask (ES-CCF) providing increased surface area by virtue of its' inner arrangement and useful in routine small-scale studies of bioactives production by any biofilm-forming marine as well as terrestrial microorganisms. Compared to corresponding Erlenmeyer flask of similar volume the ES-CCF provides more than 80% additional surface for biofilm attachment and growth. The ES-CCF does not require steam sterilization and is durable as the device is constructed of polymethyl methacrylate or any other such hydrophobic material and offers possibility of altering the nature of the growth surface (hydrophilic and hydrophobic). The ES-CCF also provides external aeration like a bioreactor, thus increasing the versatility of applications. Further, the device can be operated as a cylindrical flask, that is without the inner arrangement.

Подробнее

Номер записи: 19

06-12-2012 дата публикации

Piezoelectric dispenser with a longitudinal transducer and replaceable capillary tube

Номер: US20120304929A1

Автор: Yehuda Ivri

Принадлежит: Biodot Inc

Systems, devices and methods are provided, for acquiring and dispensing predetermined volumes of liquids and, in particular, to a unique piezoelectric dispenser for acquiring and dispensing of small volumes of fluid in an automatic or manual production of DNA arrays and assays, wherein droplets are dispensed in a single drop format with volumes that may range from about a few picoliters to several nanoliters. The dispenser can advantageously utilize a disposable capillary tube assembly while desirably retaining the piezoelectric actuator for subsequent further uses, thereby mitigating the possibility of cross contamination of fluids and providing an economical and cost effective approach with reuse of the piezoelectric actuator for further operation such as with a variety of liquids to be dispensed and transferred. A unique longitudinal transducer can transmit radial tube displacement into controlled axial motion of the tube.

Подробнее

Номер записи: 20

06-12-2012 дата публикации

Microprocessing for preparing a polycondensate

Номер: US20120309956A1

Автор: Bruno Frederic Stengel, Christof Franz Kuesters, J. Brandner, W. Benzinger

Принадлежит: Cargill Inc

The present invention relates to a process for preparing polydextrose by using a microdevice. It further relates to the use of a microdevice for the polycondesation reactions.

Подробнее

Номер записи: 21

13-12-2012 дата публикации

Assembly and method for the filtration of a liquid and use in microscopy

Номер: US20120315664A1

Автор: Karsten Hiltawsky, Katja Friedrich, Peter Paulicka, Walter Gumbrecht

Принадлежит: SIEMENS AG

An assembly and method are disclosed for the filtration of a liquid and the use thereof, wherein a supporting body is designed in a recess of a carrier and a filter membrane lies flat on the supporting body. The filter membrane and the supporting body are designed to be permeable to liquids and thus serve as filters, in particular for filtering tumor cells from blood. The carrier can having standard shapes of an object carrier for microscopy and the filtration residue on the filter membrane can be easily handled and examined in the microscope. As a result of the filter membrane lying level on the supporting body, the filtration residue can be particularly well examined microscopically.

Подробнее

Номер записи: 22

03-01-2013 дата публикации

Method and system for transferring and/or concentrating a sample

Номер: US20130000738A1

Автор: Jeffrey R. Krogmeier, Jonathan W. Larson, Robert H. Meltzer

Принадлежит: PathoGenetix Inc

A method of controlling the concentration of a sample flowing through a microchannel is provided. The method includes flowing a sample carrier fluid from a sample carrier channel and into an upstream portion of a microchannel such that the sample carrier fluid flows from the upstream portion and toward a downstream portion of the microchannel, and flowing a sheathing fluid from a sheathing fluid channel and into the upstream portion of the microchannel such that the sheathing fluid flows from the upstream portion and toward the downstream portion of the microchannel, and generally parallel to the sample carrier fluid. The method further includes detecting a concentration of a sample in the sample carrier fluid in the downstream portion of the microchannel, and adjusting a flow rate of at least one of the sample carrier fluid and the sheathing fluid based upon the detected concentration of the sample.

Подробнее

Номер записи: 23

17-01-2013 дата публикации

Bioprinting station, assembly comprising such bioprinting station and bioprinting method

Номер: US20130017564A1

Автор: Fabien Guillemot, Jean-Christophe Fricain, Sylvain Catros, Virginie Keriquel

Принадлежит: Institut National de la Sante et de la Recherche Medicale INSERM

Bioprinting station (1) comprising:—a Bioprinting device (4) adapted to deposit a pattern of biological material (2) onto an area of interest (3 a ) of a substrate (3),—an imaging system (15) adapted to acquire an image of the substrate (3) and to reveal on the acquired image the area of interest (3 a ) with respect to a remaining part (3 b ) of the substrate (3), the acquired image of the substrate (3) being processed so as to detect the revealed area of interest (3 a ) on the acquired image and to determine the pattern corresponding to the area of interest (3 a ) detected on the acquired image.

Подробнее

Номер записи: 24

17-01-2013 дата публикации

Fluid sample collecting and analyzing apparatus and method

Номер: US20130017623A1

Автор: John Wu, Waiping Ng

Принадлежит: Ameditech Inc

A spongy swab ( 16 ) is mounted against the distal face ( 15 ) of a piston ( 14 ) at the end of a push-rod ( 12 ). Once humected with a sample fluid, the swab and piston assembly is inserted into a tubular body ( 30 ) like the plunger of a syringe. As the swab is pushed and squeezed against the distal end ( 20 ) of the body up to a trippable stop, part of the fluid is excreted into a chromatographic immunoassay testing device ( 21 ) through a first aperture ( 19 ) in a distal section of the body. The remainder of the sample is kept in a sealed chamber ( 7 ) between the piston and the end wall of the tubular body until it is excreted through a second aperture ( 23 ) for a secondary test by pushing the piston beyond the trippable stop. That preserves the sample within the spongy swab that has been used to collect it; thus preventing the adsorption of the analytes on the surfaces of the sealed chamber, and to provide a convenient and rapid way to extract the remainder of the specimen in a syringe-like manner.

Подробнее

Номер записи: 25

31-01-2013 дата публикации

Mechanically Integrated and Closely Coupled Print Head and Mist Source

Номер: US20130029032A1

Автор: Bruce H. King, Gregory James Marquez, Michael J. Renn

Принадлежит: Optomec Inc

A deposition apparatus comprising one or more atomizers structurally integrated with a deposition head. The entire head may be replaceable, and prefilled with material. The deposition head may comprise multiple nozzles. Also an apparatus for three dimensional materials deposition comprising a tiltable deposition head attached to a non-tiltable atomizer. Also methods and apparatuses for depositing different materials either simultaneously or sequentially.

Подробнее

Номер записи: 26

28-02-2013 дата публикации

High throughput screening of ion channels

Номер: US20130048511A1

Автор: Edward D. Verdonk

Принадлежит: Molecular Devices LLC

Multi-well plates having contoured well designs allow multi-stage high throughput parallel assaying of ion channels or ion transporters. A well of a multi-well plate has a bottom region that is sized and shaped to simultaneously accommodate a sensing electrode and a pipette for delivering test compounds, wash fluid, and optionally ligands. The multi-well plates when coupled with an instrument having a pipette head and an electrode plate facilitates fluidic contact between cells and fluids delivered via a pipette for washing of wells with buffers or other wash solutions for serial exposure of test cells to various reagents or other stimuli. The control and test experiments are performed on the same cell (or cells) in a single well.

Подробнее

Номер записи: 27

14-03-2013 дата публикации

Method and device for the metered addition of fluids into reaction vessels

Номер: US20130064738A1

Автор: Andreas MÄCHLER, Christine Schnetz, Fritz Bircher, Manfred Schär, Philipp Haslebacher, Stefan Berger

Принадлежит: RESEACHEM GmbH

Proposed is a metering device ( 87, 54 ) for introducing a fluid ( 31 ) into a reaction vessel such as, for example, a bioreactor ( 2 ). The metering device according to the disclosure comprises a closure element ( 89 ) for closing the reaction vessel, at least one drop generator ( 33 ) arranged in the closure element, and a feed line ( 91 ) serving for feeding the fluid to the at least one drop generator. The drop generator comprises a nozzle ( 36 ) for dispensing the fluid into the reaction vessel, and a valve ( 35 ). In the closed state, the valve disconnects the nozzle from the feed line. The drop generator is suitable for generating individual drops of the fluid.

Подробнее

Номер записи: 28

21-03-2013 дата публикации

DEVICE AND METHOD FOR THE COMPLETE UPTAKE OF LIQUIDS FROM VESSELS

Номер: US20130068042A1

Автор: Á Brassard Lothar, Jäntges Uwe

Принадлежит: PERKINELMER CHEMAGEN TECHNOLOGIE GMBH

A device is provided for the complete uptake of liquids from vessels using removal units having removal tips. The removal tips or the vessel bottoms are configured or arranged relative to one another such that the area of the surface of a vessel bottom on which the respective removal tip would touch down, when that removal tip is inserted into the vessel, and the end surface of the removal tip are tilted relative to each another, at least on a portion of the two surfaces. That is to say, the surfaces are not parallel there. 110-. (canceled)11. A device for taking up liquid from a vessel having a bottom with a curved surface , the device comprising a removal unit having a removal tip formed as a channel surrounded by a wall , the removal tip having at its end an end surface defined by the surrounding wall , wherein the removal tip or the vessel bottom is configured or arranged relative to each other such that an area of the surface of the vessel bottom on which the removal tip would touch down , when the removal tip is inserted into the vessel , and an area of the end surface of the removal tip are tilted relative to each other at least in one portion of the two surface areas , such that the two surface areas are not parallel at the tilted portion , and wherein the removal tip is arranged eccentrically to an apex of curvature of the vessel bottom surface , such that when the removal tip touches down on the vessel bottom there will always result a gap between the at least one portion of the surface area of the vessel bottom and the end surface area of the removal tip , so that the removal tip is prevented from suctioning to the vessel bottom and the liquid flows through the gap into the removal unit.12. The device according to claim 11 , wherein the bottom surface of the vessel is positioned so as to be oblique relative to the end surface of the removal tip.13. The device according to claim 11 , wherein the end surface of the removal tip is beveled relative to a ...

Подробнее

Номер записи: 29

28-03-2013 дата публикации

Sampling device and method of use thereof

Номер: US20130074581A1

Автор: II Howard William Ward, Joel Michael Hawkins, Peter Alfred Blacklin, Wayne Fowler, JR.

Принадлежит: Mettler Toledo AG

An sampling device for capturing a material sample and a method of using said device to process said material sample in situ within the device. Embodiments of the invention may be disposed as elongate probes having extendable sample capture elements. A sample capture element of such a device may include a sample capture pocket located near a distal end thereof for capturing and trapping a sample of material. The sample capture pocket may be provided with a port for receiving material therein and a port for expelling material therefrom. These ports may be placed in communication with corresponding material transfer channels extending through the sample capture element to allow for the in situ processing of a material sample, and the subsequent discharge of the sample to an analyzer or another downstream location.

Подробнее

Номер записи: 30

28-03-2013 дата публикации

Device for Forming Drops in a Microfluidic Circuit

Номер: US20130078164A1

Автор: Charles Baroud, Remi Dangla

Принадлежит: ECOLE POLYTECHNIQUE

The invention relates to a device ( 1 ) for forming droplets in a microfluidic circuit, the device comprising a chamber ( 3 ) containing a first fluid and defined by two opposite walls ( 10, 11 ) that diverge relative to each other in at least one given direction, and a microchannel ( 8 ) containing a second fluid and leading into a zone of said chamber ( 3 ) that is upstream relative to the given direction, the outlet of the microchannel ( 8 ) into the chamber ( 3 ) constituting an enlargement in the flow section for the second fluid, and the enlargement giving rise to droplets ( 14 ) of the second fluid forming within the first fluid.

Подробнее

Номер записи: 31

18-04-2013 дата публикации

LABORATORY SYRINGE PUMPS

Номер: US20130092244A1

Автор: Bennett Richard K., Davis Mark, Edwards Bruce H., McKenna Andrew J., Piccirillo Justin M., Sostek Ron Y.

Принадлежит: HARVARD APPARATUS, INC.

A syringe pump which includes a pusher block is slidably mounted on bearings on one or more guide rails. The pusher block is advanced or retracted by a lead screw having an axis which is offset from the axis of the one or more guide rails which are supported at their respective ends by support blocks, wherein forward and/or trailing sides of the pusher block bearings are extended, and wherein the guide rail support blocks include recesses for accommodating the extended ends of the pusher block slide bearings. In another embodiment, the syringe pump includes quick connect-disconnect fixtures for loading and unloading syringes. Other mechanical, and programmable improvements are described in the specification. 110-. (canceled)11. The method of claim 24 , and including the steps of removing and replacing or refilling one of the syringes while the another syringe or syringes are dispensing or withdrawing fluid at the desired flow rate.12. The method of claim 24 , wherein the syringes are adjusted to dispense fluid at a constant volume flow rate claim 24 , or a constant pressure or a constant force.13. The method of claim 24 , wherein the syringes are adjusted to withdraw fluid at a constant volume flow rate claim 24 , or a constant pressure claim 24 , or a constant force.1423-. (canceled)24. A method for maintaining smooth and consistent flow rates to and from a syringe pump system having at least two syringes claim 24 , comprising the steps of:(a) adjusting one of the syringes to a desired flow rate;(b) at a predetermined time before the one syringe is depleted, reducing the flow rate from the one syringe, while simultaneously increasing a flow rate from another syringe to match the reduction in flow rate from the one syringe, and combining the flow volumes from the one and the another syringe into a single flow channel;(c) adjusting the flow rate from the one syringe to zero, while simultaneously adjusting the another syringe to the desired flow rate;(d) refilling or ...

Подробнее

Номер записи: 32

18-04-2013 дата публикации

CARTRIDGE

Номер: US20130095010A1

Автор: Koyama Takashi

Принадлежит:

A cartridge capable of storing a chemical solution includes a first container, a second container installed within the first container and configured to store the chemical solution, and an exhaust path configured to exhaust a gas generated by the chemical solution stored in the second container, wherein the exhaust path is disposed between the first container and the second container. 1. A cartridge capable of storing a chemical solution , comprising:a first container;a second container installed within the first container and configured to store the chemical solution; andan exhaust path configured to exhaust a gas generated by the chemical solution stored in the second container, wherein the exhaust path is disposed between the first container and the second container.2. The cartridge according to claim 1 , further comprising an adsorbent configured to adsorb the gas exhausted from the second container claim 1 , wherein the absorbent is disposed between the first container and the second container.3. The cartridge according to claim 1 , further comprising a decomposition agent configured to decompose the gas exhausted from the second container claim 1 , wherein the decomposition agent is disposed between the first container and the second container.4. The cartridge according to claim 1 , wherein at least a portion of the exhaust path is formed in a first packing having waterproof and moisture permeability properties disposed in an opening of the second container.5. The cartridge according to claim 1 , wherein at least a portion of the exhaust path is formed in a second packing including a first exhaust mechanism pressure bonded to the first container configured to exhaust the gas exhausted from the second container from the first container.6. The cartridge according to claim 1 , wherein at least a portion of the exhaust path is formed in a lid of the first container including a second exhaust mechanism configured to exhaust the gas exhausted from the second ...

Подробнее

Номер записи: 33

18-04-2013 дата публикации

INSTRUMENTED PIPETTE

Номер: US20130095508A1

Автор: Campitelli Andrew Paul, Harvey Erol Craig, McCormack John Edward, Schuenemann Matthias, Solomon Matthew Daniel, Wilkinson Edward Francis, Wilkinson Michael William

Принадлежит: MINIFAB (AUSTRALIA) PTY LTD

A pipette component for use in performing an experimental procedure with a fluid sample and a pipette, the pipette component including: a pipette interface configured to engage sealingly and separably with a body of the pipette; a tip interface configured to engage sealingly and separably with a replaceable tip; and an experiment region configured to receive at least part of the fluid sample by operation of the pipette, and configured to perform at least part of the experimental procedure in the experiment region using the at least part of the fluid sample. 130.-. (canceled)31. A pipette component for use in performing an experimental procedure with a fluid sample and a pipette , the pipette component including:a pipette interface configured to engage sealingly and separably with a body of the pipette;a tip interface configured to engage sealingly and separably with a replaceable tip; andan experiment region configured to receive at least part of the fluid sample by operation of the pipette, and configured to perform at least part of the experimental procedure in the experiment region using the at least part of the fluid sample.32. The pipette component of claim 31 , wherein the pipette interface includes a generally circular socket including elastic material configured to engage around a distal end of a shaft of the body of the pipette.33. The pipette component of claim 31 , including a bearing surface configured to receive an ejecting force applied by an ejector of the pipette to eject the pipette component from the pipette; optionally the pipette component including: a housing with the pipette interface and the tip interface; and a sliding member claim 31 , slidingly attached to the housing to slide relative to the housing claim 31 , and configured to receive an ejecting force applied by an ejector of the pipette to eject the replaceable tip from the pipette component.34. The pipette component of claim 31 , wherein the experiment region includes at least one ...

Подробнее

Номер записи: 34

25-04-2013 дата публикации

Apparatus and method for filter cleaning by ultrasound backwashing and filter movement during the filtration of biological samples

Номер: US20130098827A1

Автор: Stephen Curran

Принадлежит: Smith and Nephew PLC

The present application is directed to the separation of a solid fraction from a fluid sample particularly a therapeutic cellular fraction from a biological sample such as a bone marrow sample by a porous filter which separates a filtration unit into an upper pre-filtration chamber into which a fluid sample requiring cell separation is introduced and a lower post-filtration chamber into which a fluid capable of transmitting an acoustic standing wave is introduced. An acoustic element is coupled to a substrate which is located within and at the bottom of the lower chamber and which resonates in response to the acoustic generating element and generates a standing wave through the two fluid phases and the filter to agitate the sample. Simultaneously, a cyclic process of vacuum draw, causes movement of the sample downwards through the filter. Vacuum pressure, fluid flow rate and frequency of vibration are controlled from a remote unit housing appropriate pumps and valves.

Подробнее

Номер записи: 35

25-04-2013 дата публикации

CARTRIDGE AND METERING DEVICE FOR FLUID-TESTING STRIPS

Номер: US20130098939A1

Автор: Fuhrmann Karl, Zeleny Johannes

Принадлежит: Jabil Circuit, Inc.

A cartridge for holding and ejecting fluid test strips and a test-strip metering device for use with such a cartridge. The cartridge holds the test strips in a sheet-like configuration. The metering device is able to extract test strips from the cartridge in response to an actuation of a single user-interface element. The metering device may test the fluids as each is extracted. 1. A cartridge comprising:a first support structure configured to hold a first array of flat test-strips for fluids, wherein the first support structure is configured to hold test-strips side-by-side such that the first array has a sheet-like configuration within the first support structure; anda thin-walled housing encompassing the first support structure.2. The cartridge of claim 1 , further comprising a second support structure configured to hold a second array of flat test-strips claim 1 , wherein the second support structure is configured to hold the second array of test-strips adjacent and parallel to the first array of flat test-strips.3. The cartridge of claim 2 , wherein the second support structure is equivalent to the first support structure claim 2 , and wherein claim 2 , with respect to the first support structure claim 2 , the second support structure is rotated in a flat plane by 180° around a geometric center of the cartridge.4. The cartridge of claim 1 , wherein the cartridge is sized and shaped to be roughly similar in size to a credit card.5. The cartridge of claim 1 , further comprising a mechanism configured to push a first test-strip at least partially through an opening in the housing claim 1 , whereby the first test-strip may be removed from the cartridge.6. The cartridge of claim 5 , further comprising a second mechanism operable to move the first array of test-strips in a direction toward the opening claim 5 , wherein the second mechanism is configured to move the first array of test-strips in response to the first test-strip being removed from the cartridge.7. The ...

Подробнее

Номер записи: 36

25-04-2013 дата публикации

Bio chip

Номер: US20130101480A1

Автор: Bo Sung Ku, Jeong Suong YANG

Принадлежит: Samsung Electro Mechanics Co Ltd

There is provided a bio-chip. The bio-chip includes: a first substrate including a plurality of micro-wells formed in one surface thereof to a predetermined depth, the bottom face of each micro-well being hydrophilic and a lateral side thereof being hydrophobic; and a second substrate combined with the first substrate and including amounts of biomaterials inserted into the micro-wells, the amounts of biomaterials being provided at predetermined intervals.

Подробнее

Номер записи: 37

02-05-2013 дата публикации

DISCHARGE DEVICE AND LIQUID DISPENSING DEVICE, AND METHOD FOR DISPENSING LIQUID

Номер: US20130108521A1

Автор: Ikushima Kazumasa

Принадлежит: MUSASHI ENGINEERING, INC.

The discharge device includes a nozzle unit, a storage unit for supplying a pressure transmission medium under regulated pressure to the nozzle unit side, a pressurization unit for supplying a pressurized gas under regulated pressure to the storage unit side, a pump mechanism, a branch unit for communicating the nozzle unit, the storage unit, and the pump mechanism with each other, a discharge valve for establishing or blocking communication between the branch unit and the nozzle unit, and a supply valve for establishing or blocking communication between the branch unit and the storage unit. In a state of the discharge valve being closed and the supply valve being opened, the pressurized gas under pressure regulated by the pressurization unit is supplied to the storage unit side and the pressure transmission medium in liquid phase under pressure regulated by the storage unit is supplied to the supply valve side. 1. A discharge device for sucking a discharge liquid in an amount corresponding to plural discharges through a discharge port of a nozzle unit having a flow passage , which is filled with a pressure transmission medium , with a gap interposed between the pressure transmission medium and the discharge liquid , and for continuously fly-discharging very small amounts of liquid droplets , the discharge device comprising:the nozzle unit having the flow passage that is communicated with the discharge port;a storage unit for supplying the pressure transmission medium in liquid phase under regulated pressure to the nozzle unit side;a pressurization unit for supplying a pressurized gas under regulated pressure to the storage unit side;a pump mechanism communicated with the storage unit and the nozzle unit in a fluid communicating way;a branch unit provided with a branched flow passage for communicating the nozzle unit, the storage unit, and the pump mechanism with each other;a discharge valve for establishing or blocking communication between the branch unit and the ...

Подробнее

Номер записи: 38

02-05-2013 дата публикации

TAPE CASSETTE AND METHOD FOR THE MANUFACTURE THEREOF

Номер: US20130108524A1

Автор: Freitag Christian, Jaeck Thomas, Porsch Ulrich, Schaefer Jens, Seelig Peter

Принадлежит: ROCHE DIAGNOSTICS OPERATIONS, INC.

There is disclosed a tape cassette having a reeled-up carrier tape that carries at least one type of functional elements, namely test elements and/or puncturing elements, that are arranged at a distance from each other in a tape direction. The distances in the tape direction from a functional element to the next functional element of the same type change periodically in space at a period P. Moreover, there is disclosed a method for manufacture of a tape cassette of this type. 1. A tape cassette comprising a reeled-up carrier tape that carries test elements with detection regions for analysis of a sample of a human or animal body fluid that are arranged at a distance from each other in a tape direction , wherein the distances in the tape direction from a test element to the next test element change periodically in space at a period P.2. A tape cassette according to claim 1 , wherein the distances within period P change by more than a length of one test element as measured in the tape direction.3. A tape cassette according to claim 1 , wherein the distances within period P vary at least 5%.4. A tape cassette according to claim 1 , wherein the distances within period P vary at least 10%.5. A tape cassette according to claim 1 , wherein within period P there is a difference between a largest distance and a smallest distance in the tape direction from a test element to the next test element of at least 5% of the smallest distance.6. A tape cassette according to claim 5 , wherein the difference is at least 10%.7. A tape cassette according to claim 1 , wherein within period P there is a difference between a largest distance and a smallest distance in the tape direction from a test element to the next test element of no more than 50% of the smallest distance.8. A tape cassette according to claim 7 , wherein the difference is no more than 40%.9. A tape cassette according to claim 7 , wherein the difference is no more than 35%.10. A tape cassette according to claim 7 , ...

Подробнее

Номер записи: 39

09-05-2013 дата публикации

Tip for pipetting device including a part capable of protecting said device

Номер: US20130112015A1

Автор: Frédéric FOUCAULT

Принадлежит: bioMerieux SA

A tip capable of being fitted onto the body of a device for pipetting a liquid including a distal part intended for receiving the liquid sampled by the pipetting device, said distal part having a free distal end via which the liquid is aspirated and discharged, a middle part, joined to the distal part, intended to come into contact, via its free proximal end, with the body of said pipetting device and make it possible for said tip to be fixed on said body, a proximal part joined to the middle part and passed through by the body of said pipetting device when said tip is fitted on said body, said proximal part being intended for protecting said body and preventing any contact between the pipetting device and the liquid, said tip being characterized in that the proximal part is not in contact with the body of the pipetting device.

Подробнее

Номер записи: 40

16-05-2013 дата публикации

Microfluidic device with deformable valve

Номер: US20130121893A1

Автор: Emmanuel Delamarche, Laetitia C. Avrain, Martina Hitzbleck, Pascal Y. Mertens, Thierry C. Laurent, Valérie SMEKENS

Принадлежит: Coris Bioconcept SPRL, International Business Machines Corp

A microfluidic device includes a first microchannel, a second microchannel, and a valve comprising at least an input port and an output port, the ports respectively connected to the first microchannel and the second microchannel, the valve designed to control a flow of a liquid along a flow direction (z) defined by the ports; wherein the valve further comprises one or more walls joining the ports and defining a hollow chamber that is wider than each of the microchannels in a direction perpendicular to the flow direction, the walls at least partly deformable along a deformation direction (−y) intersecting the flow direction, such that the walls can be given at least a first deformation state and a second deformation state, such that the liquid can be pulled along the flow direction substantially more in the second deformation state than in the first deformation state.

Подробнее

Номер записи: 41

30-05-2013 дата публикации

SYSTEM AND METHOD INCLUDING ANALYTICAL UNITS

Номер: US20130136670A1

Автор: WILTSIE Joshua D.

Принадлежит: Beckman Coulter, Inc.

Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples. 173.-. (canceled)74. A pipettor for transferring liquids on an automated instrument comprising:a linear actuator;a piston enclosed within a barrel, the piston comprising a fluid tight seal with the inner wall of the barrel, the piston and the barrel cooperatively configured to allow movement of the piston within the barrel; anda compliant coupling interposed between the linear actuator and the piston, the compliant coupling having a first connecting feature affixing the compliant coupling to the linear actuator, a second connecting feature affixing the compliant coupling to the piston, and a compressible member interposed between the first connecting feature and the second connecting feature, the compliant coupling providing an attachment between the piston and the linear actuator.75. The pipettor of claim 74 , wherein the compressible member comprises a spring.76. The pipettor of claim 74 , wherein the first connecting feature comprises an upper plate and the second connecting feature comprises a lower plate.77. The pipettor of claim 74 , further comprising a linear step motor coupled to the linear actuator.78. The pipettor of claim 74 , ...

Подробнее

Номер записи: 42

30-05-2013 дата публикации

Electrically Conductive Pipette Tip

Номер: US20130136672A1

Автор: Christian Ziegmann, Matthias Haak, Michael Blumentritt, Nico Gülzow, Thomas Reimann

Принадлежит: Eppendorf SE

An electrically conductive pipette tip having an elongated tubular body that has a bottom opening at the bottom end for the passage of liquid, and a top opening at the top end for the passage of air, and a passageway between the bottom opening and the top opening, wherein the body has at least one electrically-conductive region extending from the bottom opening to the top opening, and at least one transparent region consisting of plastic that extends from the passageway to the outside of the body.

Подробнее

Номер записи: 43

30-05-2013 дата публикации

System and method including analytical units

Номер: US20130137110A1

Автор: Charles S. Kraihanzel

Принадлежит: Beckman Coulter Inc

Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.

Подробнее

Номер записи: 44

13-06-2013 дата публикации

Systems and methods for high speed array printing and hybridization

Номер: US20130150266A1

Автор: Holger Eickhoff, Thomas C. Tisone

Принадлежит: Biodot Inc

Novel and improved systems and methods for high speed arraying, hybridization, quantitative development and/or assaying are provided. Some embodiments provide a web based arraying format. Some other embodiments provide a sheet based arraying format. Some embodiments use a drop on drop assaying or hybridization mode. In some embodiments, a substantially inert substrate is utilized. In some other embodiments, an interactive substrate is utilized.

Подробнее

Номер записи: 45

20-06-2013 дата публикации

ADHESION METHOD, AND BIOCHEMICAL CHIP AND OPTICAL COMPONENT MADE BY THE SAME

Номер: US20130157059A1

Автор: Ogawa Kazufumi

Принадлежит:

An adhesion method capable of strongly adhering two members without using an adhesive and without impairing a fine structure or optical properties of a joining surface, and a biochemical chip and optical component made by the same are provided. 18-. (canceled)9. An optical component comprising:a first member and a second member, on a first joining surface of the first member, a first coating film of a first film compound having a first functional group at an end of its molecule and covalently bonded to the first joining surface at another end thereof;', 'on a second joining surface of the second member, a second coating film of a second film compound having a second functional group at an end of its molecule and covalently bonded to the second joining surface at another end thereof;', 'the first functional group and the second functional group are covalently bonded to each other via bonds formed by coupling reactions: between the first functional group and a coupling agent having at least one first coupling reactive group configured to form a covalent bond by a coupling reaction with the first functional group and at least one second coupling reactive group that is configured to form a covalent bond by a coupling reaction with the second functional group; and between the second functional group and the coupling agent, the first joining surface is adhered to the second joining surface via the formed bonds;', 'the first functional group comprises an epoxy group;', 'the second functional group comprises an epoxy group; and', 'the coupling agent comprises an imidazole., 'wherein10. (canceled)11. The optical component of claim 9 , wherein each of the coating film of the first film compound and the coating film of the second film compound is a monomolecular film.12. The optical component of which is a light transmissive member.13. The optical component of which is a lens claim 9 , a prism claim 9 , an optical fiber claim 9 , or an optical recording medium.15. The optical ...

Подробнее

Номер записи: 46

27-06-2013 дата публикации

PIPETTE TIP HANDLING DEVICES AND METHODS

Номер: US20130161347A1

Автор: Motadel Arta

Принадлежит: BIOTIX, INC.

Discussed herein are methods and devices for storing, handling, loading or dispensing of pipette tips. Some embodiments allow repetitive loading of an array of multiple pipette tips that are stored in a nested configuration. 1. A pipette tip dispensing device , comprising:a housing configured to engage a pipette tip rack;a distal barrier plate in connection with the housing, which distal barrier plate comprises a substantially flat top surface, a substantially flat bottom surface and channels; the channels comprise a first subset of channels and a second subset of channels, and', 'the distal barrier plate is configured to eject pipette tips in the array through the first set of channels at a first time and eject pipette tips in the array through the second set of channels at a second time different than the first time., 'an array of nested pipette tip units, each of which nested pipette tip units is aligned with a channel in the distal barrier plate, whereby a one-layer pipette tip array is aligned with the channels; wherein2. The pipette tip dispensing device of claim 1 , wherein:the distal barrier plate comprises one or more structures in or around the channels in the first subset of channels and the channels in the second subset of channels,the one or more structures are configured to apply a first frictional force to pipette tips in the array ejected through the first subset of channels and a second frictional force to pipette tips in the array ejected through the second subset of channels, andthe second frictional force is different than the first frictional force.3. The pipette tip dispensing device of claim 2 , wherein the one or more structures are chosen from presence or absence of different channel diameter; different channel textures; and one of more projections around the channels and extending from the top surface claim 2 , the bottom surface claim 2 , or the top surface and the bottom surface of the plate claim 2 , or a combination thereof.4. The ...

Подробнее

Номер записи: 47

27-06-2013 дата публикации

PIPETTE TIPS

Номер: US20130164194A1

Автор: BLASZCAK Peter Paul, Callahan Sean Michael, Hairfield Phillip Chad, Motadel Arta

Принадлежит: BIOTIX, INC.

Disclosed here are pipette tips useful for acquiring or dispelling liquids, and include one or more design that may increase fluid delivery precision and/or accuracy, and may reduce certain repetitive motions. 1. A pipette tip comprising a proximal region and a distal region , wherein:the proximal region comprises an exterior surface and an annular flange at the proximal terminus of the proximal region;the proximal region comprises a first set of axially oriented ribs and a second set of axially oriented ribs;the ribs of the first set and the second set are circumferentially spaced and alternately spaced around the exterior surface of the proximal region; andribs of the first set have a maximum thickness greater than the maximum thickness of ribs of the second set.2. The pipette tip of claim 1 , wherein:the distal region wall thickness tapers from (a) a point at or between (i) about the junction of the proximal region and distal region to (ii) about one-quarter of the axial distance from the terminus of the distal region to the junction, to (b) the distal region terminus, andthe wall thickness at the distal region terminus is about 0.0040 inches to about 0.0055 inches.3. The pipette tip of embodiment 2 claim 1 , wherein the wall thickness at the distal region terminus is about 0.0043 inches to about 0.0050 inches.4. The pipette tip of claim 3 , wherein the wall thickness at the distal region terminus is about 0.0044 inches to about 0.0049 inches.5. The pipette tip of claim 4 , wherein the pipette tip retains less than 0.065% of a fluid drawn into the pipette tip after the liquid is dispensed.6. The pipette tip of claim 5 , wherein the pipette tip retains no more than 0.00012% of a fluid drawn into the pipette tip after the liquid is dispensed.7. The pipette tip of claim 4 , wherein less than 3.72% of the pipette tips retain a portion of the fluid drawn into the pipette tips after the liquid is dispensed.8. The pipette tip of claim 7 , wherein between 0.2% to 0.26% ...

Подробнее

Номер записи: 48

04-07-2013 дата публикации

PIPETTE TIP, PIPETTE SYSTEM AND METHOD FOR PERFORMING ANALYSIS WITH THE PIPETTE TIP AND SYSTEM

Номер: US20130171673A1

Автор: Fan Linsey, Follonier Stéphane, Indermuhle Pierre

Принадлежит: CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICRO- TECHNIQUE SA RECHERCHE ET DEVELO

The present invention relates to a pipette tip () comprising a tip body () having an inner surface and an outer surface (). The inner surface () defines an inner cavity (), which has an upper end and a lower end. The upper end has an upper opening (); and the lower end has a lower opening (). At least a part of the inner surface () is provided with capturing agents () of at least one type forming at least one capturing-agent region () on the at least one inner surface. The at least one capturing agent region () is capable of selectively binding target substances () of at least one type comprised in a sample to form at least agent-target conjugates (), the arrangement of which define at least one agent-target region (). 2. The pipette tip according to comprising at least one EM waveguiding medium operative and configured to guide at least some of the light emanating from said at least one agent-target region.3. The pipette tip according to claim 2 , wherein said at least one EM waveguiding medium is selected from one or more members a group consisting of: a side wall claim 2 , and a cavity of said pipette tip.4. The pipette tip according to claim 2 , wherein said at least one EM waveguiding medium comprises a medium selected from a group consisting of:a medium having a refractive index that is different from the index of refraction of its surrounding medium;a medium surrounded by an inner light-reflecting surface;a medium surrounded by an outer light-reflecting surface;at least one refracting layer having varying indexes of refraction such to render said at least one dielectric layer EM waveguiding; andphotonic-crystal fibers.5. The pipette tip according to comprising a light-shield covering at least some portion of said tip body to shield said at least one EM waveguiding medium from external light.6. The pipette tip according to wherein at least some part of the pipette tip is retractable into said portion of said tip body that is covered by said light-shield.7500. ...

Подробнее

Номер записи: 49

01-08-2013 дата публикации

Packaging and applicator device using a pipette

Номер: US20130192713A1

Автор: Jean-Francois Delage, Jean-Marc Lebrand, Lionel Drugeon, Thierry Ramboz

Принадлежит: LOreal SA

Packaging and dispensing device comprising a receptacle ( 2 ) and a pipette ( 31 ) designed to be inserted into the receptacle in order to permit the collection of a dose of product, the pipette being connected to a closure member ( 3 ) for closing the receptacle, characterized in that the closure member is provided with a piston pump ( 28 ) designed to aspirate the liquid into the pipette during the passage of this closure member from a closed position to an opened position of the receptacle, the pump being equipped with a push button ( 5 ) in order to permit the aspiration of product when the closure member is not in the closed position.

Подробнее

Номер записи: 50

01-08-2013 дата публикации

Method for Heating a Volume of Liquid in a Heated Pipetting Needle

Номер: US20130195718A1

Автор: Michels Thorsten, Selvi Ayhan, Wiedekind-Klein Alexander

Принадлежит: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH

The invention relates to a pipetting device for automatic analysis instruments and a method for heating a volume of liquid in a heated pipetting needle. 1. A method for heating a volume of liquid in a heated pipetting needle with a closed-loop controllable heating device and a region in which a temperature sensor is mounted , wherein the method comprises the following steps:a) drawing in the desired volume of liquid and thenb) drawing in a volume of air,and whereinthe volume of air is selected such that the volume of liquid reaches the region of the heated pipetting needle in which the temperature sensor is mounted and completely passes through this region.2. The method as claimed in claim 1 , wherein the pipetting needle has a constant intended temperature.3. The method as claimed in claim 2 , wherein the temperature sensor only activates the heating device if the intended temperature is undershot.4. The method as claimed in claim 1 , wherein the method furthermore comprises the following step:c) dispensing the drawn-in volume of air and liquid,wherein no additional incubation of the volume of air and liquid in the pipetting needle is undertaken between drawing in and dispensing.5. A device for pipetting a volume of liquid claim 1 , wherein the device comprises the following components:a) a heatable pipetting needle with a closed-loop controllable heating device and a region in which a temperature sensor is mounted;b) means for setting a constant intended temperature of the pipetting needle;c) means for setting a desired volume of liquid to be drawn in;d) means for setting a volume of air to be drawn in, wherein the volume of air to be drawn in is selected dependent on the volume of liquid to be drawn in such that the previously drawn-in volume of liquid reaches the region of the pipetting needle in which the temperature sensor is mounted and completely passes through this region.6. An analysis instrument for automatically analyzing samples claim 5 , comprising a ...

Подробнее

Номер записи: 51

01-08-2013 дата публикации

Capillary dispenser

Номер: US20130195733A1

Автор: Adrian Siemers

Принадлежит: CYBIO AG

A capillary dispenser includes at least one plunger-cylinder unit having a cylinder module and a plunger module disposed together on an axis. The cylinder module has an inner cylinder that is pneumatically connected to at least one capillary. The plunger module includes a hollow plunger that is closable on one side and is movable in the inner cylinder along the axis between an upper end position and a lower end position of the plunger module.

Подробнее

Номер записи: 52

08-08-2013 дата публикации

Filtered Adapter for Pipettors

Номер: US20130203089A1

Автор: Kaucic Edward M., Mao Guoqiang, Martin Timothy, Meredith Tim, Wingo James P.

Принадлежит: Porex Corporation

The present invention relates to an adapter containing a filter that can be used with pipetting devices, particularly robotic pipetting devices, to efficiently connect the pipetting device to pipette tips with minimal distortion of the pipette tip. The present invention also relates to a process and a system of using an adapter containing a filter that can be used with pipetting devices, particularly robotic pipetting devices, to assemble the adapter together with an unfiltered pipette tip on the site of application. The adapter and pipette tip are each stackable for saving space at the work station. 114.-. (canceled)15. An adapter for use with a pipetting device and a pipette tip comprising:a deformable housing containing non-porous plastic or rubber walls surrounding a lumen;a filter comprising a sintered porous plastic filter or a fiber filter, wherein the filter is located in the lumen in a manner to provide a barrier to fluid and aerosol.16. The adapter of claim 15 , wherein an inner wall of the adapter claim 15 , an outer wall of the adapter claim 15 , or both the inner wall and outer wall of the adapter contain a sealing means or a circumferential ridge.17. The pipette tip of claim 16 , wherein an inner wall of the pipette tip claim 16 , an outer wall of the pipette tip claim 16 , or both the inner wall and outer wall of the pipette tip contains a circumferential indentation or groove.18. The adapter of claim 15 , wherein the filter comprises a color change indicator.19. The adapter of claim 15 , wherein the filter comprises a self sealing additive.20. The adapter of claim 15 , wherein the sintered porous plastic in the filter is sintered porous polyethylene claim 15 , polypropylene claim 15 , PVDF or PTFE claim 15 , or a combination thereof.21. The adapter of claim 15 , wherein the adapter is stackable.22. A rack containing the adapter of .23. The rack of claim 22 , wherein the rack is stackable.24. A method for performing automated pipetting comprising the ...

Подробнее

Номер записи: 53

15-08-2013 дата публикации

AUTOMATED VISUAL PIPETTING

Номер: US20130205920A1

Автор: Tow Adam Perry

Принадлежит:

A system and method is described for Automated Visual Pipetting on a machine such as a three dimensional fabrication device like a 3D Printer or other computer numerical control (CNC) machine tools, for improved speed, accuracy and reliability in pipetting procedures. A camera is mounted on a pipette or another type of tool that may be a deposition or non-deposition tool (e.g., milling). A camera feed and recognition software can enable users to replace existing micro-pipetting techniques with a computerized process that may be controlled with a few simple mouse clicks, while the user can directly visualize a live experimental setup. The embodiment also allows for integration with common molecular biology procedure “kits,” and enables the process to be automated and visualized without requiring constant interaction by the user. 1. A three dimensional pipetting device , comprising:a control unit for receiving instructions from a pipetting command unit and operating a pipetting tool head; anda plurality of interchangeable pipetting tips that can be affixed to the pipetting tool head;wherein the control unit can operate the pipetting tool head to selectively use one of the plurality of interchangeable pipetting tips; andwherein the control unit can operate the pipetting tool head to selectively draw up liquid from one or more containers on a work surface;wherein the control unit can operate the pipetting tool head to selectively dispense liquid into the one or more containers on the work surface.2. A three dimensional pipetting device , comprising:a control unit for receiving instructions from a pipetting command unit and operating a pipetting tool head; anda camera for recording data including the position of one or more containers on a work surface;wherein the control unit can operate the pipetting tool head to selectively draw up liquid from the one or more containers on the work surface; andwherein the control unit can operate the pipetting tool head to selectively ...

Подробнее

Номер записи: 54

15-08-2013 дата публикации

MICROFLUIDIC DEVICE AND METHOD FOR PRODUCING SAME

Номер: US20130206253A1

Автор: Blankenstein Gert, Kurowski Dirk, Osterloh Dirk, Prenger Marc, Yu Ying

Принадлежит:

A microfluidic device and a method of producing it are proposed, in which a film covers a chamber in a carrier. The film is locally re-tightened in the region of the chamber after the film has been secured to the carrier. In this way it is possible to prevent undesirable bulging of the film into the chamber. 1134353464. Device () , having a carrier () , a film () attached to the carrier () and a chamber () formed in the carrier () and open towards the film () , which is covered by a film portion () of the film () ,characterised in that{'b': 1', '6, 'the device () comprises a tightening means for tightening the film portion ().'}2114. Device according to claim 1 , characterised in that the tightening means has a deformation region () for the film ().311334. Device according to claim 2 , characterised in that the deformation region () is formed or arranged in or on the carrier () on a flat side of the carrier () facing the film ().411123411. Device according to claim 2 , characterised in that the deformation region () comprises or is formed by a groove-like depression () in the carrier () and/or the film () is deformed into the deformation region () at least substantially abuts thereon or is connected thereto.511213155. Device according to claim 2 , characterised in that the deformation region () comprises or is formed by a bead-like elevation () of the carrier () claim 2 , that forms an edge () of the chamber ().6111555. Device according to claim 2 , characterised in that the deformation region () extends along an edge () of the chamber () and/or at least substantially completely surrounds the chamber ().7115. Device according to claim 2 , characterised in that in each case a deformation region () is arranged or formed on opposite sides of the chamber ().843101616105. Device according to claim 1 , characterised in that the film () is connected to the carrier () in a first attachment region () and in a second attachment region () claim 1 , while the second attachment ...

Подробнее

Номер записи: 55

15-08-2013 дата публикации

Droplet Actuator Assemblies and Methods of Making Same

Номер: US20130206597A1

Автор: Bort Donovan E., Brackett George, Clevenger David, Wang Tih-Hong

Принадлежит: ADVANCED LIQUID LOGIC, INC.

The invention provides droplet actuator assemblies and systems and methods of manufacturing the droplet actuator assemblies. In certain embodiments, two-piece enclosures are used to form a droplet actuator assembly that houses a droplet operations substrate. In certain other embodiments, one-piece enclosures are used to form a droplet actuator assembly that houses a droplet operations substrate. In the plastic injection molding process for forming substrates of the droplet actuator assemblies of the present invention may utilize insert molding (or overmolding) processes for forming a gasket in at least one substrate, thereby avoiding the need for providing and installing a separate gasket component. Further, the droplet actuator assemblies may include features that allow ultrasonic welding processes to be used for bonding substrates together. The manufacturing systems of the present invention for fabricating the droplet actuator assemblies may utilize continuous flow reel-to-reel manufacturing processes. 174-. (canceled)75. A droplet actuator , comprising:(a) a droplet operations substrate having droplet operations electrodes arranged on a side thereof and a top substrate separated by a gap when assembled;(b) one or more gap setting features provided between the droplet operations substrate and the top substrate; and(c) one or more bonding features formed on the gap facing side of the top substrate.76. The droplet actuator of wherein the one or more bonding features comprise block-shaped features having energy director features formed thereon77. The droplet actuator of wherein the droplet operations substrate comprises a PCB.78. The droplet actuator of wherein the top substrate comprises one of PC claim 75 , MDH12 claim 75 , COP claim 75 , COC claim 75 , and/or thermoplastic.79. The droplet actuator of wherein the droplet operations electrodes comprise electrowetting electrodes.80. The droplet actuator of further comprising a dielectric layer formed on the droplet ...

Подробнее

Номер записи: 56

15-08-2013 дата публикации

Microfluidic chips and assay systems

Номер: US20130209327A1

Автор: Lincoln C. Young, Peng Zhou

Принадлежит: Rheonix Inc

The systems and methods described herein include a microfluidic chip having a plurality of microfeatures interconnected to provide a configurable fluid transport system for processing at least one reagent. Inserts are provided to removably interfit into one or more of the microfeatures of the chip, wherein the inserts include sites for interactions with the reagent. As will be seen from the following description, the microfluidic chip and the inserts provide an efficient and accurate approach for conducting parallel assays.

Подробнее

Номер записи: 57

15-08-2013 дата публикации

Microfluidic chip comprising several cylinder-piston arrangements

Номер: US20130209328A1

Автор: Daniel Latta, Klaus-Stefan Dresse, Marion Ritzi-Lehnert, Tina Roeser

Принадлежит: INSTITUT FUER MIKROTECHNIK MAINZ GMBH

A microfluidic arrangement including a substrate in which a mircofluidic structure having several adjacent channels and at least one common supply line, into which the adjacent channels merge, is formed. Each of the adjacent channels form the cylinder of a cylinder-piston arrangement for receiving an associated piston. A method for producing the type of microfluidic-arrangement is also disclosed.

Подробнее

Номер записи: 58

15-08-2013 дата публикации

System and method including analytical units

Номер: US20130209334A1

Автор: Alan N. Johnson, Brian D. Wilson, Daniel R. Schmidt, David L. Anderson, Joshua D. Wiltsie, Matthew D. Erickson, Michael J. Rosen

Принадлежит: Beckman Coulter Inc

Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.

Подробнее

Номер записи: 59

22-08-2013 дата публикации

Pipette Tip

Номер: US20130213151A1

Автор: Beese Jochen

Принадлежит: Eppendorf AG

A pipette tip having the shape of an elongate small tube with a lower opening at the lower end for the passage of liquid, and an upper opening at the upper end, wherein a seat area exists on the inner circumference contiguous to the upper opening, which serves for plugging it onto a standardized conical attachment piece of a pipetting device, wherein the seat area has a retaining area with axially extending ribs projecting radially towards the inside, and below the retaining area a sealing area and is configured such that when the pipette tip is plugged onto the attachment piece with its seat area by a plugging force which ensures retaining and sealing of the pipette tip on the attachment piece, the ribs are partly plastically deformed, and elastic deformation occurs in the seat area outside of the ribs. 14363063730301112111913730137123012. A pipette tip having the shape of an elongate small tube with a lower opening () at a lower end () for the passage of liquid , and an upper opening () at the upper end , wherein a seat area () exists on an inner circumference contiguous to the upper opening () , which serves for plugging it onto a standardized conical attachment piece () of a pipetting device () , wherein the seat area () has a retaining area () with axially extending ribs () projecting radially towards the inside , and below the retaining area () a sealing area () and is configured such that when the pipette tip () is plugged onto the attachment piece () with its seat area () by a plugging force which ensures retaining and sealing of the pipette tip () on the attachment piece () , the ribs () are partly plastically deformed , and elastic deformation occurs in the seat area () outside of the ribs ().212. The pipette tip according to claim 1 , wherein the ribs () are uniformly distributed over the circumference.312. A pipette tip according to claim 1 , which has 3 to 12 ribs () claim 1 , preferably 5 to 7 ribs claim 1 , and further preferably 6 ribs.4123737137137. ...

Подробнее

Номер записи: 60

22-08-2013 дата публикации

System and method for liquid delivery evaluation using solutions with multiple light absorbance spectral features

Номер: US20130214217A1

Автор: Ceara McNally, Charles A. Ewing, John Thomas Bradshaw, Richard H. Curtis

Принадлежит: Artel Inc

A system and related method for improved liquid delivery evaluation using a solution containing one or more dyes such that the solution exhibits multiple distinct detectable light absorbance spectral features for calibrating or testing over extended volume or dilution ranges are described. The system includes: a photometric instrument capable of measuring optical absorbance at multiple wavelengths; one or more sample solutions to be dispensed using the liquid delivery system whose performance is being tested or calibrated; and vessels optionally pre-filled, or filled by the user, with diluent solution. The sample solutions contain one or more dyes, chosen so that multiple distinct detectable light absorbance spectral features, such as peaks and/or valleys and/or plateaus of the solution can be distinguished for volume or dilution ranges of interest. The concentrations of the dyes may be chosen so that a large volume delivery device is calibrated using a spectral feature in the solution with a low absorbance per unit pathlength, while a small volume delivery device is calibrated with the same sample solution but using a different spectral feature with a high absorbance per unit pathlength.

Подробнее

Номер записи: 61

29-08-2013 дата публикации

Manual Dosing Device

Номер: US20130224087A1

Автор: REICHMUTH Burkhardt

Принадлежит: Eppendorf AG

A manual dosing device comprising 1. A manual dosing device comprising{'b': '1', 'an elongated frame () as a support structure,'}{'b': 8', '30', '1', '30', '2', '35', '1, 'means for releasably holding (, ., ., ) a syringe or a pipette tip that are arranged at the bottom end of the frame (),'}{'b': 36', '41', '8', '30', '1', '30', '2', '1, 'drive means (, ), that are fastened above the means for releasably holding (, ., .) to the frame (),'}{'b': 34', '36', '41', '8', '30', '1', '30', '2', '31', '1', '31', '4', '35, 'at least one displacement means () for displacing a fluid in the syringe or pipette tip that can be driven by the drive means (, ) and is connected to the means for releasably holding (, ., ., .-., ), and'}{'b': 24', '1, 'a housing () encasing the frame ().'}2123. The manual dosing device according to claim 1 , wherein the frame () comprises a plurality of frame parts ( claim 1 , ) that are joined and firmly connected with each other.323. The manual dosing device according to claim 2 , wherein the frame comprises a bottom part () and a top part ().4231011021210110212221222. The manual dosing device according to claim 2 , wherein the different frame parts ( claim 2 , ) comprise interlocking connecting structures (. claim 2 , . claim 2 , ) claim 2 , and these connecting structures (. claim 2 , . claim 2 , ) have fastening means (. claim 2 , .) that are connected with each other.5151526162. The manual dosing device according to claim 1 , wherein the frame () comprises spaced claim 1 , parallel longitudinal members (. claim 1 , . claim 1 , . claim 1 , .).62351615262. The manual dosing device according to claim 2 , wherein the plurality of frame parts ( claim 2 ,) comprise parallel longitudinal members (. claim 2 , .; . claim 2 , .).7151526162. The manual dosing device according to claim 6 , wherein the frame () comprises two parallel longitudinal members (. claim 6 , . claim 6 , . claim 6 , .).8515261628301302311314. The manual dosing device according to ...

Подробнее

Номер записи: 62

29-08-2013 дата публикации

Method and apparatus for control of fluid temperature and flow

Номер: US20130225059A1

Автор: Scott Davis

Принадлежит: Forced Physics LLC

Materials, components, and methods consistent with the present invention are directed to the fabrication and use of micro-scale channels with a fluid, where the temperature and flow of the fluid is controlled through the geometry of the micro-scale channel and the configuration of at least a portion of the wall of the micro-scale channel and the constituent particles that make up the fluid. Moreover, the wall of the micro-scale channel and the constituent particles are configured such that collisions between the constituent particles and the wall are substantially specular.

Подробнее

Номер записи: 63

05-09-2013 дата публикации

Method for collecting droplet attached on external surface of needle into capillary tube

Номер: US20130228224A1

Автор: Akio Hirata, Yoshitsugu URIU

Принадлежит: Panasonic Corp

In order to provide a method for collecting a droplet attached on an external surface of a needle into a capillary tube, the present invention is a method for collecting a droplet attached on an external surface of a needle into a capillary tube, the method comprising steps of (a) preparing a substrate comprising a capillary tube; a flexible thin film; a liquid-repellent film; and a hole; (b) moving the needle in the Z-direction to move the droplet from the external surface of the needle to the surface of the liquid-repellent film; (c) allowing the droplet to arrive at an inlet of the capillary tube by moving the needle more in the Z-direction, so as to suck the droplet into the capillary tube by a capillary phenomenon.

Подробнее

Номер записи: 64

12-09-2013 дата публикации

Pipette

Номер: US20130233095A1

Автор: Wilmer Jens

Принадлежит: Eppendorf AG

A pipette with a rod-shaped casing, a seat, a displacement equipment, comprising a displacement chamber with a relocatable limit, a connection channel, a drive equipment for relocating the relocatable limit of the displacement chamber, coupled to the relocatable limit and having an axially relocatable lifting rod, an upper stop body, a lower stop body and a stop element on the circumference of the lifting rod for limiting the stroke of the lifting rod, an overstroke spring, a stationary screw element, and with a screw element that is relocatable in the casing, a toothing, running along a helical line with the same pitch as that of the thread of the relocatable screw element and having teeth on the upper edge of the relocatable screw element that are directed in the direction of the instantaneous axis of the relocatable screw element, a toothed driving wheel, and means for rotating the toothed driving wheel. 1. A pipette with{'b': 2', '3, 'a rod-shaped casing (, ),'}{'b': 50', '51', '2', '3, 'a seat () for detachably holding a pipette tip () on the lower end of the casing (, ),'}{'b': 57', '58, 'a displacement equipment, comprising a displacement chamber () with a relocatable limit (),'}{'b': 56', '57, 'a connection channel (), connecting the displacement chamber () with an opening in the seat,'}{'b': 58', '57', '58', '6, 'a drive equipment for relocating the relocatable limit () of the displacement chamber (), coupled to the relocatable limit () and having an axially relocatable lifting rod (),'}{'b': 8', '27', '25', '6', '6, 'an upper stop body (), a lower stop body () and a stop element () on the circumference of the lifting rod () for limiting the stroke of the lifting rod (),'}{'b': 31', '8', '32, 'an overstroke spring (), via which the lower stop body () is supported against relocation towards the downside on an overstroke spring support (),'}{'b': 10', '2', '3', '92', '10', '27', '6', '92, 'a stationary screw element (), fixedly connected to the casing (, ), ...

Подробнее

Номер записи: 65

12-09-2013 дата публикации

PIPETTING DEVICE HAVING A LINEAR MOTOR

Номер: US20130233096A1

Автор: Romer Hanspeter, Schlegel Andreas

Принадлежит: HAMILTON BONADUZ AG

The invention relates to a pipetting device, comprising at least two pipetting channels (), which extend along a channel axis (K) and which each can be adjusted along the channel axis (K), wherein the pipetting device () has a displacement drive, by means of which each pipetting channel () can be displaced independently of the other pipetting channel () along a displacement axis (V) orthogonal to the channel axis (K) regardless of an adjustment along the channel axis (K), wherein the displacement drive comprises a linear motor, the stator of which has at least two magnet arrangements (), which comprise a row of magnets () on a magnet carrier (), said magnets being consecutive along the displacement axis (V) and being arranged differently with regard to the polarity (P P) thereof, and the armature of which (at at ); has at least one conductor loop arrangement (), which comprises at least one set of three conductor loops () that are consecutive along the displacement axis (V), each of which conductor loops is or can be associated with a different phase of a three-phase supply, wherein each pipetting channel () has at least one conductor loop arrangement (), wherein the armatures (at at ) of two pipetting channels () directly adjacent along the displacement axis (V) are associated with different magnet arrangements () and interact therewith. 1. A pipetting device having at least two pipette channels which extend along a channel axis and whereof each may be adjusted along the channel axis , wherein the pipetting device has a displacement drive by means of which each pipette channel may be displaced along a displacement axis which is at a right angle to the channel axis , independently of adjustment along the channel axis and independently of the respectively other pipette channel , wherein the displacement drive includes a linear motor whereof the stator has at least two magnet arrangements which include on a magnet support a row of magnets which succeed one another ...

Подробнее

Номер записи: 66

12-09-2013 дата публикации

Method of Manipulating a Droplet

Номер: US20130233712A1

Автор: Paik Philip, Pamula Vamsee K., Pollack Michael G., Srinivasan Vijay

Принадлежит: Advanced Liquid Logic Inc.

A method of manipulating a droplet comprising providing a substrate comprising a surface; an elongated transport electrode disposed on the substrate surface, the elongated transport electrode having a first and a second end and configured to impart a gradient force to the droplet; and one or more wires for providing power to the transport electrode; and providing power to the one or more wires to effect the gradient force and thereby transport the droplet along the length of the elongated transport electrode from the first end to the second end. 1. A method of manipulating a droplet comprising: (i) a surface;', '(ii) an elongated transport electrode disposed on the substrate surface and configured to impart a gradient force to the droplet; and', '(iii) one or more wires for providing power to the transport electrode; and, '(a) providing a substrate comprising(b) providing power to the one or more wires to effect the gradient force and thereby transport the droplet along the length of the elongated transport electrode.2. A method of manipulating a droplet comprising: (i) a surface;', '(ii) an elongated transport electrode disposed on the substrate surface, the elongated transport electrode having a first and a second end and configured to impart a gradient force to the droplet; and', '(iii) one or more wires for providing power to the transport electrode; and, '(a) providing a substrate comprising(b) providing power to the one or more wires to effect the gradient force and thereby transport the droplet along the length of the elongated transport electrode from the first end to the second end.3. The method according to wherein the elongated transport electrode includes a tapered portion between the first end and the second end claim 2 , wherein the first end comprises a narrow end and the second end comprises a wide end.4. The method according to wherein the one or more wires consist of two wires.5. The method according to further comprising another transport ...

Подробнее

Номер записи: 67

12-09-2013 дата публикации

Delivery system for analytical samples

Номер: US20130236276A1

Автор: Daniel T. Richter

Принадлежит: Individual

A system for handling sample vials includes a vault for receiving a series of storage cartridges. Inside the cartridges are one or more discs providing vial recesses. In multidisc cartridges, through passages are provided to place and retrieve vials into and from the subjacent discs. A pick up device is moved until it aligns with a selected vial and the vial is pneumatically removed. A device is provided to reverse orientation of a vial moving through the system. A venturi operated system is provided including symmetrical bleed off ports to propel vials through the system without inducing excessive spinning of the vials. A piping system from a central bank to a multiplicity of analytical instruments includes a minimum number of through conduits and a diverter at each instrument location for sending the vial either to the instrument or downstream toward another diverter and instrument.

Подробнее

Номер записи: 68

19-09-2013 дата публикации

Pipetting Device and Multi-Channel Pipetting Device

Номер: US20130239706A1

Автор: Link Holger

Принадлежит: Eppendorf AG

The invention relates to a pipetting device for pipetting at least one fluid laboratory sample into at least one pipetting vessel, said device having a main body extending along an axis direction, at least one connecting section, to which at least one pipetting vessel can be connected by an at least partially axial connecting movement along the positive axis direction, wherein the at least one connecting section is connected to the main body so as to be movable at least in the axis direction, a spring mechanism, by which the at least one connecting section is supported with spring loading on the main body at least in a first operating state of the pipetting device, such that the at least one connecting section, during the connecting movement, can perform a spring-assisted deflection movement along the positive axis direction, wherein an auxiliary mechanism is provided on the pipetting device and is designed to act on the deflection movement of the at least one connecting section in at least a second operating state of the pipetting device, wherein the pipetting device is designed such that the user can alternately put it into the first operating state or the second operating state. The invention further relates to a multi-channel pipetting device. 231131. Pipetting device according to claim 1 , wherein the auxiliary mechanism has at least one auxiliary element (; ) which is arranged movably on the pipetting device such that it can be moved by the user at least between a first position and a second position on the pipetting device by an auxiliary movement claim 1 , wherein the pipetting device is located in the first operating state in the first position claim 1 , and wherein the pipetting device is located in the second operating state in the second position.3. Pipetting device according to claim 2 , wherein the auxiliary movement is directed at least partially perpendicularly with respect to the axis direction.4. Pipetting device according to or claim 2 , wherein ...

Подробнее

Номер записи: 69

19-09-2013 дата публикации

THERMOFORMED PLASTIC LABORATORY BEAKER CONFIGURED TO STABILIZE TEMPERATURE AND RESIST TIPPING

Номер: US20130241110A1

Автор: Perlman Daniel

Принадлежит:

A thermoplastic laboratory beaker that holds liquid in a reservoir portion of the beaker, in which the beaker includes a first upright, generally circular, outer sidewall and a second inner sidewall which are united at their upper limit height to form a lip edge or lip surface. The two sidewalls typically diverge from each other below the lip surface to create an air space between them. The outer sidewall extends downward a first distance D below the lip surface, and then usually bends outward to form a substantially planar supporting flange that at least partially supports the weight of said beaker on a laboratory surface. The inner sidewall extends downward a second distance D from the lip surface, and then bends inward to form a bottom wall for the reservoir portion that intersects the central vertical axis of said beaker, in which the inner sidewall and the bottom wall form the reservoir portion for holding a liquid. 124-. (canceled)25. A method for making a double-walled beaker , comprisingthermoforming a heated thermoplastic sheet on a thermoform mold configured such that said sheet is formed into an open-topped beaker which comprisesan outer upright sidewall, an inner sidewall, and a bottom wall which together form an open-topped container,{'b': 1', '2', '2', '1, 'wherein said outer sidewall and inner sidewall are united at their upper limit forming a lip surface and diverge from each other below said lip surface creating an air space between said sidewalls, said outer sidewall extending downward a first distance D below said lip surface to a support contact area formed at the lower limit of said outer sidewall and said inner sidewall extends downward a second distance D from said lip surface and then bends inward joining with a bottom wall together forming said reservoir portion, D being equal to or less than D.'} NOT APPLICABLE.The present invention relates to the structure and fabrication of thermoplastic laboratory beakers.The following discussion is ...

Подробнее

Номер записи: 70

19-09-2013 дата публикации

Pipetting Apparatus and Method for Production Thereof

Номер: US20130243666A1

Автор: DAVID Tobias, Link Holger

Принадлежит: Eppendorf AG

The invention relates to a pipetting apparatus, in particular for pipetting a fluid sample by aspiration into a pipetting container by means of air under a pipetting pressure, said pipetting apparatus comprising: a valve arrangement having at least one valve device for setting a pipetting pressure, wherein the valve device comprises a valve chamber; at least one pump device, which is connected to the valve chamber to generate a chamber pressure in the valve chamber; a pipetting channel, to which the pipetting container can be connected, and; a bypass channel, which is open to the surrounding environment; wherein the pipetting channel and the bypass channel are each connected to the valve chamber; and wherein the at least one valve device is designed such that, to generate the desired pipetting pressure in the pipetting channel, the chamber pressure is distributed in a metered manner by the valve device between the pipetting channel and the bypass channel. The invention further relates to a method for producing this pipetting apparatus. 11999ab. Pipetting apparatus () , in particular for pipetting a fluid sample () by aspiration into a pipetting container () by means of air () under a pipetting pressure , said pipetting apparatus comprising the following{'b': 10', '100', '200', '101', '102', '101', '106', '106', '106, 'a valve arrangement (; ; ) having at least one valve device (; ; ″) for setting a pipetting pressure, wherein the valve device comprises a valve chamber (; ′; ″);'}{'b': '7', 'at least one pump device (), which is connected to the valve chamber to generate a chamber pressure in the valve chamber;'}{'b': 103', '103, 'a pipetting channel (; ″), to which the pipetting container can be connected, and'}{'b': 104', '104, 'a bypass channel (; ″), which is open to the surrounding environment;'}wherein the pipetting channel and the bypass channel are each connected to the valve chamber;and wherein the at least one valve device is designed such that, to generate ...

Подробнее

Номер записи: 71

03-10-2013 дата публикации

ELECTRONIC PIPETTE

Номер: US20130255404A1

Автор: Lurz Werner, Mohr Günther A., Von Beichmann Boris

Принадлежит: Eppendorf AG

The invention relates to an electronic pipette comprising an electrically driven unit for pipetting and an operating and/or display unit, wherein a device module comprises a unit for pipetting, an operating and/or display module physically separate from the device module completely or partially comprises the operating and/or display unit, and means are provided for wirelessly communicating between the device module and the operating and/or display module. 1. An electronic pipette comprising:{'b': '2', 'a. an electrically driven unit for pipetting (), and'}{'b': '3', 'b. an operating and/or display unit (),'}{'b': 7', '2, 'c. wherein a device module () comprises the unit for pipetting (),'}{'b': 8', '7', '3, 'd. an operating and/or display module () physically separate from the device module () completely or partially comprises the operating and/or display unit (), and'}{'b': 9', '7', '8, 'e. means are provided for wireless communication () between the device module () and the operating and/or display module ().'}27. The pipette device according to claim 1 , wherein the device module () comprises an electronic control unit for detecting operating data and/or controlling the unit for handling liquids.38. The pipette according to claim 1 , wherein the operating and/or display module () is designed such that operating parameters and/or modes of operation from the device module and/or programs can be entered by means of its operating unit to control the device module and/or routines for performing operating procedures of the device module.487. The pipette according to claim 1 , wherein the operating and/or display module () is designed such that it can be used to remotely control device modules ().58778. The pipette according to claim 1 , wherein the operating and/or display module () is designed such that it recognizes the respective device module () when communicating with one of a plurality of device modules () claim 1 , and automatically sets a device-specific user ...

Подробнее

Номер записи: 72

03-10-2013 дата публикации

Lab Members and Liquid Handling Systems and Methods Including Same

Номер: US20130259635A1

Автор: Malkowski Dennis F., Maslana Eugene S., McElroy Karen A., Sim James W.

Принадлежит: PerkinElmer Health Sciences, Inc.

A laboratory liquid handling system includes a pipetting module, a lab member, and a drive system. The pipetting module includes a pipettor including a pipettor shaft and a pipetting tip extending from an end of the pipettor shaft. The lab member includes a body and at least one adapter structure including an interlock feature configured to laterally receive and interlock with the pipettor shaft to releasably secure the lab member to the pipettor shaft. The drive system is operable to: selectively move the pipettor shaft laterally relative to the interlock structure to engage the pipettor shaft with the interlock structure to secure the lab member to the pipetting module; move the pipetting module to transport the lab member secured thereto; and selectively move the pipettor shaft laterally relative to the interlock structure to disengage the pipettor shaft from the interlock structure to thereby release the lab member. 1. A laboratory liquid handling system comprising:a pipetting module including a pipettor, the pipettor including a pipettor shaft and a pipetting tip extending from an end of the pipettor shaft;a lab member including a body and at least one adapter structure including an interlock feature configured to laterally receive and interlock with the pipettor shaft to releasably secure the lab member to the pipettor shaft; and selectively move the pipettor shaft laterally relative to the interlock structure to engage the pipettor shaft with the interlock structure to secure the lab member to the pipetting module;', 'move the pipetting module to transport the lab member secured thereto; and', 'selectively move the pipettor shaft laterally relative to the interlock structure to disengage the pipettor shaft from the interlock structure to thereby release the lab member from the pipetting module., 'a drive system operable to2. The laboratory liquid handling system of further including a cradle adapted to be engaged and transported by the lab member claim 1 , ...

Подробнее

Номер записи: 73

10-10-2013 дата публикации

LABORATORY DEVICE FOR HANDLING LIQUIDS

Номер: US20130266952A1

Автор: Behling Carsten, GOEMANN-THOSS Wolfgang, Lurz Werner, Manuello Sophie, Mohr Günther A., Von Beichmann Boris

Принадлежит: Eppendorf AG

The invention relates to a laboratory device for handling liquids comprising a unit for handling liquids and an operating and/or display unit, wherein a device module comprises the unit for handling liquids, an operating and/or display module physically separate from the device module completely or partially comprises the operating and/or display unit, and means are provided for wirelessly communicating between the device module and the operating and/or display module. 1. A laboratory device for handling liquids , comprising:{'b': '2', 'a. a unit for handling liquids (), and'}{'b': '3', 'b. an operating and/or display unit (),'}{'b': 7', '2, 'c. wherein a device module () comprises the unit for handling liquids (),'}{'b': 8', '7', '3, 'd. an operating and/or display module () physically separate from the device module () completely or partially comprises the operating and/or display unit (), and'}{'b': 9', '7', '8, 'e. means for wireless communication () between the device module () and the operating and/or display module ().'}27. The laboratory device according to claim 1 , wherein the device module () comprises an electronic control unit for detecting operating data and/or controlling the unit for handling liquids.38. The laboratory device according to claim 1 , wherein the operating and/or display module () is designed such that operating parameters and/or modes from the device module and/or programs can be entered by means of its operating unit to control the device module and/or routines for performing operating procedures of the device module.487. The laboratory device according to claim 1 , wherein the operating and/or display module () is designed so that it can be used to remotely control device modules ().58778. The laboratory device according to claim 1 , wherein the operating and/or display module () is designed such that it recognizes the respective device module () when communicating with one device module of a plurality of device modules () claim 1 , ...

Подробнее

Номер записи: 74

10-10-2013 дата публикации

MICROPLATE GUIDE FOR A PIPETTE

Номер: US20130267038A1

Автор: ANDERSIN Kati

Принадлежит: SARTORIUS BIOHIT LIQUID HANDLING OY

Microplate guide for a pipette, said guide comprising means for selecting the type of the microplate, the mode of dispensing and the dispensing direction, as well as means for indicating the next target for dispensing on the display of the pipette prior to each pipetting operation, and a method for guiding a pipetting operation, said method comprising the steps of selecting the type of microplate, selecting the mode of dispensing, and selecting the dispensing direction, followed by displaying on the display of the pipette the next target for dispensing prior to each pipetting operation. 1. A microplate guide for a pipette , characterized in that said guide comprises: means for selecting the type of microplate , the mode of dispensing and the dispensing direction , as well as means for indicating the next target for dispensing on the display of the pipette prior to each pipetting operation.2. The microplate guide according to claim 1 , further providing the option of selecting the initial target for dispensing on the microplate.3. The microplate guide according to or claim 1 , further providing the option of defining which of the wells are desired targets for dispensing claim 1 , and which of the wells are excluded from dispensing.4. The microplate guide according to claim 1 , wherein the mode of dispensing is dispensing into individual wells on a microplate.5. The microplate guide according to claim 1 , wherein the mode of dispensing is dispensing into all wells of a row of wells on a microplate.6. The microplate guide according to claim 4 , wherein dispensing into a row of wells is carried out in vertical order.7. The microplate guide according to claim 4 , wherein dispensing into a row of wells is carried out in horizontal order.8. The microplate guide according to claim 5 , wherein dispensing into all wells of a row is carried out in vertical order.9. The microplate guide according to claim 5 , wherein dispensing into all wells of a row is carried out in ...

Подробнее

Номер записи: 75

17-10-2013 дата публикации

FILTRATION DEVICE AND METHOD

Номер: US20130270173A1

Автор: Seymour Geraint, Tortorella Stevan Paul

Принадлежит: GE Healthcare UK Limited

Embodiments of the present invention relate to a filtration device for use in filtration of a liquid, and disclose: a liquid receptacle having an open end and a closed end; a plunger body moveable at least partially within the liquid receptacle along an axis said axis extending between the open and closed ends, said plunger including a filtrate chamber in fluid communication with the liquid receptacle via a fluid filtering path and a filter disposed in the filtering path, and the device further including a slidable seal for inhibiting or preventing fluid flow across the seal during said plunger movement; wherein said seal includes a first skirt depending from the plunger at one end of the first skirt, said first skirt having an outer surface which in use slidably and sealingly abuts the vial, and having, at least in an uncompressed state, a generally annular separation between the skirt and the plunger body, which separation extends generally parallel to the axis. A second skirt, overlapping the first skirt, is disclosed also. 1. A filtration device for use in filtration of a liquid , comprising:a liquid receptacle including an open end and a closed end;a plunger body moveable at least partially within the liquid receptacle along an axis said axis extending between said open and closed ends, said plunger including a filtrate chamber in fluid communication with the liquid receptacle via a fluid filtering path and a filter disposed in the filtering path, and the device further including a slidable seal for inhibiting or preventing fluid flow across the seal during said plunger movement; whereinsaid seal includes a first skirt depending from the plunger at one end of the first skirt, said first skirt including an outer surface which in use slidably and sealingly abuts the vial, and including, at least in an uncompressed state, a generally annular separation between the skirt and the plunger body, which separation extends generally parallel to the axis.2. The filtration ...

Подробнее

Номер записи: 76

24-10-2013 дата публикации

DEVICES AND METHODS FOR PROGRAMMABLE MANIPULATION OF PIPETTES

Номер: US20130280143A1

Автор: Horak Giorgio, Jordan Antoine, Zucchelli Piero

Принадлежит: Andrew Alliance S.A.

The present invention is directed generally to devices and methods for manipulating laboratory pipettes in a programmable manner. The present invention is directed to an apparatus and methods for allowing a user to instruct the device to perform a specific process; identifying the type, location and identity of the consumables to be used; manipulating a plurality of pipettes for performing the liquid handling; monitoring the process during and after its execution; generating a detailed report for the plurality of actions. Other aspects of this invention include optimization of the liquid dispensing performances of a pipette; monitoring and controlling individual actions by means of vision; virtualization of the protocol definition by means of a reality augmented software interface; integration of the system in a conventional laboratory environment workflow. 1. An apparatus for processing biological or chemical fluids , comprisingat least one pipette wherein said at least one pipette is configured to allow for a pipette volume to be determined by vision feedback;at least one mechanical arm to manipulate at least one pipette said manipulation is assisted by computer vision feedback; anda software interface governing the manipulation of the pipettes.25-. (canceled)6. The apparatus according to claim 1 , wherein the software interface allows for programming of a liquid handling protocol.7. (canceled)8. The apparatus according to claim 1 , wherein the arm manipulation includes movement of the at least one pipette claim 1 , tip insertion and ejection claim 1 , setting of the desired volumes claim 1 , aspiration and dispensing of liquids.9. The apparatus according to claim 8 , wherein the manipulation of the at least one pipette by sequences of aspiration and dispenses allows for liquid mixing.10. An apparatus for processing biological or chemical fluids claim 8 , comprisinga camera mounted on a moving arm and capable of imaging; anda deck area comprising a plurality of ...

Подробнее

Номер записи: 77

24-10-2013 дата публикации

PIPETTE TIP HAVING A HYDROPHOBIC SURFACE TEXTURE

Номер: US20130280423A1

Автор: Beckbissinger Rainer, Kirste Vinzenz, Nay Renato

Принадлежит:

The present invention relates to a pipette tip (), for aspirating and dispensing pipetting fluid, which extends along a pipette tip longitudinal axis (L), a first axial longitudinal end region () of the pipette tip (), as a pipetting longitudinal end region (), comprising a pipette opening (), through which pipetting fluid can flow in the course of operation, and a second axial longitudinal end region () of the pipette tip (), as a coupling longitudinal end region (), which opposes the pipetting longitudinal end region () in the axial direction, comprising a coupling shape, for coupling, preferably releasable coupling, to a coupling counter-shape of a pipette device, the pipette tip () comprising an outer hydrophobic region () on the outside () thereof and an inner hydrophobic region () on the inside () thereof, each having a quadratic roughness in a range of 100 nm to 1000 nm, preferably of 150 nm to 750 nm and particularly preferably of 200 nm to 500 nm, and having a peak-to-peak roughness in a range of 800 nm to 5500 nm, preferably of 1750 nm to 4500 nm and particularly preferably of 2500 nm to 3700 nm, the axial extension range of the outer hydrophobic region () and the axial extension range of the inner hydrophobic region () differing from one another. 1. Process for hydrophobically coating pipette tips , which comprises wetting at least regions of the inside of the pipette tip with a wetting solution , characterised in that it more precisely comprises the steps of:providing a holding cavity other than the pipette tip, preferably a tube member, particularly preferably a glass tube member, on a pipette device,immersing the holding cavity in the wetting solution,aspirating wetting solution into the holding cavity,connecting the pipette tip to the holding cavity,dispensing the aspirated wetting solution from the holding cavity through the pipette tip and thus rinsing a pipetting fluid holding chamber portion inside the pipette tip,evaporating solvent contained in ...

Подробнее

Номер записи: 78

31-10-2013 дата публикации

HIGH RESOLUTION PIPETTE

Номер: US20130283884A1

Автор: BEROZ Justin Douglas, Hart Anastasios John

Принадлежит: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

A pipette includes a movable piston and a diaphragm that at least partly defines a fluid chamber enclosing a volume of working fluid. The piston displaces a volumetric amount of the working fluid in the chamber when moved. In response, the diaphragm displaces a smaller volumetric amount of fluid outside the chamber. A deamplification ratio is defined by the ratio of the volume displaced by the diaphragm to the volume displaced by the piston. The deamplification ratio is adjustable by adjusting or changing the diaphragm and/or by adjusting the size of the fluid chamber. The deamplifying pipette enables measuring and dispensing of very small volumes of liquid and is easily adapted to commercially available pipette components. Pipette components such as a pipette tip or adaptor may include a diaphragm to enable deamplification of the nominal volume capacity of a given pipette device. 1. A pipette device , comprising:a fluid chamber having an enclosed volume of working fluid;a piston that partially defines the fluid chamber, the piston being movable to displace the working fluid within the fluid chamber; anda diaphragm that partially defines the fluid chamber, the diaphragm having a chamber side in contact with the working fluid and an opposite side that displaces a measurement volume of fluid outside the fluid chamber when the piston moves to displace a volumetric amount of working fluid, wherein the measurement volume is less than the volumetric amount of working fluid displaced by the piston.2. A pipette device as defined in claim 1 , wherein the working fluid is a compressible fluid.3. A pipette device as defined in claim 1 , wherein the working fluid is an incompressible fluid.4. A pipette device as defined in claim 1 , wherein the diaphragm undergoes elastic deformation when the piston moves against the enclosed volume of working fluid.5. A pipette device as defined in claim 1 , further comprising a secondary diaphragm that defines a portion of the fluid chamber ...

Подробнее

Номер записи: 79

31-10-2013 дата публикации

FILTRATION DEVICE AND METHOD

Номер: US20130284680A1

Автор: Pathirana Navin Deepal, Seymour Geraint, Tortorella Stevan Paul

Принадлежит: GE Healthcare UK Limited

Embodiments of the present invention relate to a filtration device and method for filtering liquids. In conventional devices, a liquid is placed in a vial, and a plunger, having a filter membrane located at one end, is depressed into the vial, causing the liquid to pass through the filter membrane into the interior of the plunger, where it is stored until required for further processing. However, such plungers are typically made of a plastics material. It is undesirable to store the filtered liquid in contact with plastics for extended periods of time, as contaminants may leach from the plastics material into the sample. In embodiments of the present invention, a filtrate receptacle made from a different material to the plunger, such as a glass material, is located in the interior of the plunger and the filtered liquid collected in the filtrate receptacle after passing through the filter membrane. This allows the filtered liquid to be held isolated from the plastics material, thereby protecting it from contamination. 1. A filtration device for use with a liquid receptacle for holding a liquid sample , the liquid receptacle having a closed end for holding said liquid sample , the filtration device comprising:a plunger body made of a first material, the plunger body comprising an internal chamber;a filter material; anda filtrate receptacle within the internal chamber of the plunger body, the filtrate receptacle being made of a second material, the second material being different from the first material,wherein the filtration device is arranged to be slidably movable in the liquid receptacle so that the filter material moves towards said closed end of the liquid receptacle,wherein said movement causes liquid held in said liquid receptacle to pass through said filter material to the internal chamber of the plunger body, thereby filtering the liquid, the filtered liquid passing into said filtrate receptacle.2. The filtration device of claim 1 , wherein said second ...

Подробнее

Номер записи: 80

31-10-2013 дата публикации

Electric Pipetting Apparatus, and Method for Operating an Electric Pipetting Apparatus

Номер: US20130288382A1

Автор: ANDRES Karl-Friedrich, JACOBI Janine, MOLITOR Peter, Schmidt Peter

Принадлежит:

The invention relates to a pipetting apparatus, for pipetting a fluid sample in accordance with at least one mode of operation of the pipetting apparatus, which is controlled by an operating parameter set, which is associated with a corresponding mode of operation, wherein the electric control device of the pipetting apparatus is designed to automatically store the at least one parameter value set determined by the user to be the at least one historic parameter value set for this mode of operation in the memory device, and is designed to provide, after the operating parameter set for this mode of operation has changed, the at least one automatically stored historic parameter value set for this mode of operation again for the subsequent control of the at least one, same, pipetting process. The invention also relates to a method for operating the pipetting apparatus. 2. Pipetting apparatus according to claim 1 , wherein the electric control device is designed to perform the automatic storage of the parameter value set after the user has selected this parameter value set.3. Pipetting apparatus according to or claim 1 , wherein the electric control device is designed to perform the automatic storage of the parameter value set after the pipetting process has been performed completely at least once.4. Pipetting apparatus according to at least one of the preceding claims claim 1 , wherein the memory device is used to store at least one collection (operating parameter selection history) of a number N1 of historic parameter value sets with which the user is respectively provided and which the user can respectively select.5. Pipetting apparatus according to claim 4 , wherein the pipetting apparatus is designed to prompt a number N2 of collections of a number N1 of historic parameter value sets to be stored claim 4 , wherein each collection of parameter value sets is associated with a particular mode of operation and wherein the user is respectively provided with a collection ...

Подробнее

Номер записи: 81

07-11-2013 дата публикации

Pipette

Номер: US20130291660A1

Автор: Wilmer Jens, WINTER Ingo

Принадлежит: Eppendorf AG

A pipette for use with pipette tips in which a set metering volume is secured in that the locking body is arranged on the circumference of the annular cylindrical locking element when it is in the locking position. Through this, the transmission part which the locking element comprises on the outer circumference is held fast. The annular cylindrical locking element can be formed separately from a toothed ring for driving a counter mechanism. Thus, it is possible to perform the locking in arbitrary positions or in more selectable rotational positions than in the conventional locking equipment, where a locking element engages into the toothed ring for driving the counter mechanism. 1. A pipette comprising:{'b': 1', '1, 'a rod-shaped casing (.),'}{'b': 50', '51', '1', '1, 'a seat () for detachably holding a pipette tip () on the lower end of the casing (.),'}{'b': 57', '58, 'a displacement equipment, comprising a displacement chamber () with a limit () that is relocatable therein,'}{'b': 56', '57', '50, 'a connection channel (), connecting the displacement chamber () with an opening in the seat (),'}{'b': 6', '58', '58, 'a drive equipment (), coupled to the relocatable limit (), for relocating the relocatable limit () of the displacement chamber,'}{'b': 8', '25', '27', '58', '6, 'adjustable means (, , ) for limiting the relocation of the relocatable limit () by the drive equipment (),'}{'b': 4', '6', '1', '1', '58', '8', '25', '27', '4, 'an actuating element (), connected to the drive equipment () and projecting out from the upper end of the casing (.), for controlling a relocation of the relocatable limit () by relocation along an axis, and for adjusting the adjustable means (, , ) for limiting by rotating the actuating element (),'}{'b': 19', '1', '1', '4', '19', '19', '15', '16', '17', '18, 'a cylindrical transmission part (), which is rotatable in the casing (.) and bearing mounted at a certain position in the axial direction, wherein the actuating element () is ...

Подробнее

Номер записи: 82

14-11-2013 дата публикации

CONTROLLED PRESSURE RELEASE VESSEL FOR MICROWAVE ASSISTED CHEMISTRY

Номер: US20130302220A1

Автор: Hargett, Jr. Wyatt Price

Принадлежит:

A controlled release and self-resealing vessel assembly for high pressure microwave assisted chemistry is disclosed. The vessel assembly includes a microwave-transparent, heat expandable reaction vessel having at least two cylindrical portions axially adjacent one another, with one of the portions having a diameter larger than the diameter of the other portion. A transition portion is between the two cylindrical portions, the vessel mouth is in the larger-diameter portion, and a cylindrical retaining sleeve surrounds the vessel. 1. A controlled release and self-resealing vessel assembly for high pressure microwave assisted chemistry , said vessel assembly comprising:a microwave-transparent, heat expandable reaction vessel having at least two cylindrical portions axially adjacent one another with one of said portions having a diameter larger than the diameter of the other portion;a transition portion between said two cylindrical portions;a vessel mouth in said larger-diameter portion; anda cylindrical retaining sleeve around said vessel.2. A vessel assembly according to wherein said larger-diameter portion is defined by an outer diameter approximately equal to the inner diameter of said sleeve and said smaller-diameter portion is defined by an outer diameter smaller than said inner diameter of said sleeve.3. A vessel assembly according to wherein said transition portion is stepped.4. A vessel assembly according to wherein said transition portion is beveled.5. A vessel assembly according to further comprising:a plug for closing said mouth; a threaded lid; and a threaded outer wall of said reaction vessel for engaging said lid to urge said plug into said mouth.6. A vessel assembly according to wherein said vessel claim 5 , said plug and said lid are all formed of a fluoropolymer.7. A vessel assembly according to wherein said retaining sleeve is formed of a material selected from the group consisting of polymers; reinforced polymers claim 1 , and composite materials. ...

Подробнее

Номер записи: 83

14-11-2013 дата публикации

Encoded microcarriers, assay system using them and method for performing an assay

Номер: US20130302910A1

Автор: Nicolas Demierre

Принадлежит: BIOCARTIS SA

The present invention relates to an encoded microcarrier comprising a readable code attached to it for identification, said encoded microcarrier comprising a body having at least a detection surface to detect a chemical and/or biological reaction, the microcarrier further comprising at least a spacing element projecting from the body and shaped to ensure that, when the encoded microcarrier is laid on a flat plane with the detection surface facing said flat plane, a gap exists between said flat plane and the detection surface. The invention also relates to an assay device designed to use a plurality of said encoded microcarriers to perform assays. The invention relates finally to a method for monitoring a chemical or biological reaction.

Подробнее

Номер записи: 84

21-11-2013 дата публикации

Mechanical Pipette

Номер: US20130305844A1

Автор: Lurz Werner, Mohr Günther A., Von Beichmann Boris

Принадлежит: Eppendorf AG

A mechanical pipette comprising: 1. A mechanical pipette comprising:{'b': '2', 'a manually drivable mechanical unit for pipetting liquids (),'}at least one sensor for detecting operating and/or performance data,an operating unit, and{'b': '3', 'a display unit (),'}{'b': '7', 'wherein a device module () comprises the mechanical unit for pipetting, the sensor and operating unit,'}{'b': 7', '8', '3, 'a display module () physically separate from the device module () that completely or partially comprises the display unit (), and'}{'b': 9', '7', '8, 'means for wireless communication () between the device module () and the display module ().'}27. The pipette according to claim 1 , wherein the device module () comprises an electronic control unit for detecting operating data and/or performance data.38778. The pipette according to claim 1 , wherein the display module () is designed such that it recognizes the respective device module () when communicating with one of a plurality of device modules () claim 1 , and automatically sets a device-specific user interface on the display unit ().48. The pipette according to claim 1 , wherein the display module () is designed so that it can only be used when a proof of authorization is entered.58. The pipette according to claim 1 , wherein the display module () is designed such that certain measuring results and other data can only be processed when proof of authorization is entered.68. The pipette according to claim 1 , wherein the display module () is designed to have a reservation function by means of which the pipette can be blocked for certain intervals for certain users.78. The pipette according to claim 1 , wherein the display module () has switches and/or keys and/or a keyboard and/or a microphone and/or a screen and/or a touch-sensitive screen and/or a loudspeaker and/or an acoustic signal generator.878. The pipette according to claim 1 , wherein the device module () is handheld claim 1 , and/or the operating display module ...

Подробнее

Номер записи: 85

21-11-2013 дата публикации

Method of using a disposable pipette tip

Номер: US20130306155A1

Автор: COTE Richard, Kelly Terrance, Mathus Gregory

Принадлежит: INTEGRA BIOSCIENCES CORP.

The pipetting method is directed to mounting and ejecting a disposable pipette tip. The pipetting system has one or more tip mounting shafts with an upper locking section and a lower sealing section. The upper locking section has outwardly extending lobes spaced around the mounting shaft and located above a stop member. The lower sealing section on the tip mounting shaft is located below the stop. As the mounting shaft is inserted into the collar of the disposable pipette, the collar distorts out of round and engages the lobes on the upper locking section of the tip mounting shaft. Contemporaneously, the lower sealing section of the mounting shaft seals against the barrel of the disposable pipette tip. 120-. (canceled)21. A method of using a disposable pipette tip with a pipetting system , the method comprising the steps of:providing a disposable pipette tip comprising a barrel having a lower opening through which liquid is aspirated into the barrel and dispensed from the barrel, an upper portion having an inside surface with a circular circumference and an upper end having a circular circumference and an inside diameter, the disposable pipette tip also comprising a collar having a continuous inner surface with a circular circumference in its relaxed state, an upper opening of the collar for receiving a tip mounting shaft on the pipetting system, and a lower end of the collar with a circular circumference in its relaxed state and an inside diameter that is larger than the inside diameter of the upper end of the barrel, and a circumferential shelf connecting the lower end of the collar to the upper end of the barrel;providing at least one tip mounting shaft on the pipetting system, the tip mounting shaft including an internal bore through which air is displaced in order to aspirate liquid sample into and dispense liquid sample from the pipette tip, said tip mounting shaft having a lower sealing section, an upper locking section, a stop located between the upper ...

Подробнее

Номер записи: 86

21-11-2013 дата публикации

Pipette tip with improved seal

Номер: US20130309144A1

Автор: Weiming Yu

Принадлежит: GENE ERA BIOTECH CO Ltd

The present invention provides a pipette tip member with improved seal.

Подробнее

Номер записи: 87

28-11-2013 дата публикации

PIPETTE AND SEALING TIP

Номер: US20130312545A1

Автор: Petrek James S.

Принадлежит: Rainin Instrument, LLC

A sealing pipette tip includes features to seal the tip directly against the piston in an air displacement pipette, avoiding the need for a piston seal within the pipette. This configuration reduces potential points of failure, allows the pipette-tip interface to be optimized, and improves liquid handling characteristics of the pipette. 1. A pipette tip for use with an air displacement pipette that includes a tip mounting shaft and a piston mounted for axial movement within the shaft , the shaft having a distal end and an interior surface , and the interior surface defining an interior space around the piston , the tip having a generally elongated tubular configuration and comprising:a mount portion including an open proximal end and an inward-facing sealing region; anda liquid handling portion including a tapered open distal end;wherein the mount portion is adapted for sliding insertion into the distal end of the shaft; andwherein, when the pipette tip is mounted on the shaft, the mount portion of the pipette tip extends into the interior space between the piston and the interior surface of the shaft, the piston penetrates the open proximal end of the pipette tip and is axially movable within the mount portion of the tip, the sealing region of the pipette tip forms an air tight seal against the piston, and an air volume is maintained between a distal face of the piston and any liquid in the pipette tip, the axial movement of the piston causing the liquid to be displaced.2. The pipette tip of claim 1 , wherein the inward-facing sealing region comprises a projecting sealing ring.3. The pipette tip of claim 5 , wherein the sealing ring is adapted to be compressed against the piston by the tip mounting shaft when the tip is mounted on the shaft.4. The pipette tip of claim 2 , wherein the sealing ring has a diameter smaller than the diameter of the piston when the tip is not mounted on the shaft.5. The pipette tip of claim 2 , wherein the sealing ring has an ...

Подробнее

Номер записи: 88

28-11-2013 дата публикации

Test chip and test chip unit incorporated with test chip

Номер: US20130312546A1

Автор: Shigeru Wada

Принадлежит: KONICA MINOLTA INC

The present invention is characterized in being provided with a chip main body, which is provided with a flow channel having the end portion thereof opened in the surface, and a sheet-like sealing member, which brings the inside of the flow channel into a hermetically closed state by covering at least the opening in the surface of the chip main body. The present invention is also characterized in that in the sealing member, a plurality of sheets are laminated, said sheets including a first sheet, which has ductility and elasticity such that the first sheet can be penetrated by means of a nozzle member, and a second sheet having ductility lower than that of the first sheet, the sheets adjacent to each other are bonded with an adhesive agent or a cohesive agent, and that the second sheet is positioned further toward the chip main body side than the first sheet.

Подробнее

Номер записи: 89

28-11-2013 дата публикации

Method of dispensing analytic reference material

Номер: US20130313281A1

Автор: Brian A. Jones, Thomas E. Kane

Принадлежит: Restek Corp

A method of dispensing an analytic reference material includes providing a dispensing device including an ampoule having at least two storage lumens extending axially along the length of an ampoule body, an analytic reference material subunit in each of the storage lumens, distal gaskets sealing the analytic reference material subunits from a distal end of the ampoule, and an outlet lumen. The method also includes providing a plunger assembly coupled to a proximal end of the ampoule, the plunger assembly in communication with the storage lumens and depressing the plunger assembly to force the distal gaskets into gasket seats in the dispensing device and expelling the analytic reference material subunits from the storage lumens via the outlet lumen to form the analytic reference material.

Подробнее

Номер записи: 90

28-11-2013 дата публикации

LIGHT BEAM GUIDED LIQUID DELIVERY DEVICE

Номер: US20130315797A1

Автор: CARR David A., Weller Jennifer W.

Принадлежит: THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE

A light beam guided liquid delivery device, including: a liquid delivery device; a light beam generator; and a bracket coupling the light beam generator to the liquid delivery device such that a beam of light is selectively delivered approximate to a tip of the liquid delivery device. The bracket couples the light beam generator to the liquid delivery device at a first attachment point. The bracket includes one or more hinges at the first attachment point for varying the orientation of the light beam generator. Optionally, the bracket also couples the light beam generator to the liquid delivery device at a second contact point. The bracket includes a support member at the second contact point for varying the orientation of the light beam generator. Optionally, the support member is translatable with respect to the one or more hinges along a length of the bracket. 1. A light beam guided liquid delivery device , comprising:a liquid delivery device for selectively drawing in and expelling a liquid;a light beam generator for selectively delivering a beam of light; anda bracket coupling the light beam generator to the liquid delivery device such that the beam of light is selectively delivered approximate to a tip of the liquid delivery device.2. The light beam guided liquid delivery device of claim 1 , wherein the bracket couples the light beam generator to the liquid delivery device at a first attachment point.3. The light beam guided liquid delivery device of claim 2 , wherein the bracket comprises one or more hinges at the first attachment point for varying the orientation of the light beam generator with respect to the liquid delivery device.4. The light beam guided liquid delivery device of claim 2 , wherein the bracket also couples the light beam generator to the liquid delivery device at a second contact point.5. The light beam guided liquid delivery device of claim 4 , wherein the bracket comprises a support member at the second contact point for varying the ...

Подробнее

Номер записи: 91

05-12-2013 дата публикации

Pipette for operating a syringe

Номер: US20130319139A1

Автор: Belgardt Herbert, REICHMUTH Burkhardt, Sattler Jörg, Schmidt Winfried

Принадлежит: Eppendorf AG

Pipette for operating a syringe with a bar-shaped housing, a fixture with an opening at the lower end of the housing for putting in a syringe with a fastening portion on the upper edge of a cylinder, a fixture body with a further fixture and a further opening on the lower end of the housing, for putting in a further fastening portion of a piston of the syringe, means for detachably holding the fastening portion in the fixture and the further fastening portion in the further fixture, means for displacing the fixture body within the housing in the longitudinal direction of the housing, which have a draw-up lever activated from the outside of the housing, which is connected to the fixture body via a connection element which grips through a straight slit extending in the longitudinal direction of the housing, wherein below the slit in the housing, a cover stripe covering the slit is held in the housing at two positions spaced apart from each other in the longitudinal direction of the slit, and wherein the connection element has a channel through which the cover stripe extends. 1. Pipette for actuating a syringe , comprising:{'b': '2', 'a bar-shaped housing (),'}{'b': 20', '21', '1', '2', '3', '16', '11, 'a fixture () with an opening (.) at the lower end of the housing () for putting in a syringe () with a fastening portion () on the upper edge of a cylinder (),'}{'b': 25', '24', '21', '2', '2', '19', '12', '3, 'a fixture body () with a further fixture () and a further opening (.) on the lower end of the housing (), for putting in a further fastening portion () of a piston () of the syringe (),'}{'b': 23', '26', '16', '20', '19', '24, 'means for detachably holding (, ) the fastening portion () in the fixture () and the further fastening portion () in the further fixture (),'}{'b': 5', '8', '34', '37', '27', '25', '2', '2, 'means for displacing (, , , , ) the fixture body () within the housing () in the longitudinal direction of the housing (),'}{'b': 5', '2', '25', '62', ...

Подробнее

Номер записи: 92

05-12-2013 дата публикации

System for performing automated solid phase extractions

Номер: US20130323138A1

Автор: Thomas J. Demmitt

Принадлежит: Biolytic Lab Performance Inc

The invention provides an improved instrument for automation of solid phase extraction chemistries typically used in biotechnology labs. The instrument includes a mechanism for transferring samples dissolved in a liquid from initial containers to reaction columns that are used to perform solid phase extractions. Samples, reaction columns and collection containers are in microtiter plate format or tubes that are on 18 millimeter centers. The transfer system is automatically cleaned after use in preparation for the next use. A dispense manifold is used to dispense various reagents into the reaction columns. Pressure differential is used to move reagents through reaction columns. A sliding cover is used to divert the reagent exiting reaction columns to waste or allowing collection of sample as it exits outlets of reaction columns. Samples are automatically collected in microtiter plates or in individual tubes or vials.

Подробнее

Номер записи: 93

12-12-2013 дата публикации

MOUNTING SYSTEMS FOR A SURFACE FORCES APPARATUS

Номер: US20130327161A1

Автор: Israelachvili Jacob

Принадлежит:

A mounting system for samples and instruments for use with a measuring device such as a surface forces apparatus has a housing and a sample mount assembly positioned within the housing. The sample mount assembly has a pivot arm having a first edge and a flexing section. A spring has a first end coupled to the pivot arm. A first sample holder is coupled to the second end of the spring. A second sample holder is positioned in proximity to the first sample holder. 1. A sample mount assembly for a surface forces apparatus , the sample mount assembly comprising:a pivot arm;the pivot arm comprising a flange along one edge for being received in a mounting slot of the surface forces apparatus;the pivot arm further comprising a body portion and a flexible section extending between the flange and the body portion such that the body portion can flex relative to the flange;the body portion having a mounting arrangement whereby a sample holder of the surface forces apparatus can be mounted to the body portion.2. A sample mount assembly according to claim 1 , wherein the mounting arrangement comprises at least one slot through the body portion for receiving a fastener to fasten a coupling block of the sample holder to the body portion.3. A sample mount assembly according to claim 1 , comprising a coupling block mounted to the body portion claim 1 , a spring having a first end mounted to the coupling block and a second end to which is mounted a sample holder.4. The sample mount assembly of claim 3 , wherein the sample holder enables the testing of biological samples.58-. (canceled)9. The sample mount assembly of claim 3 , wherein the sample holder comprises a prefabricated surface.10. The sample mount assembly of claim 9 , wherein the prefabricated surface is removable.11. The sample mount assembly of claim 1 , wherein the sample holder comprises a sealed chamber for preventing exposure of electronic devices in the chamber to corrosive substances.12. The sample mount assembly of ...

Подробнее

Номер записи: 94

12-12-2013 дата публикации

CELL ISOLATION APPARATUS

Номер: US20130330248A1

Автор: KUBO Hirotsugu, SHIOYAMA Takahiro, SUZUKI Akane

Принадлежит: Nihon Kohden Corporation

A cell isolation apparatus in which tissue and fluid that are accommodated in a container are pipetted by a pipette, and cells are isolated from the tissue, the cell isolation apparatus includes: a nozzle to which the pipette is attached; a pump which is connected to the nozzle; a controller which is configured to control an operation of the pump to cause air to be ejected from the nozzle or to be sucked into the nozzle, thereby causing the pipette to perform pipetting; and a condition inputting unit in which a user inputs a condition of control of the controller. 1. A cell isolation apparatus in which tissue and fluid that are accommodated in a container are pipetted by a pipette , and cells are isolated from the tissue , the cell isolation apparatus comprising:a nozzle to which the pipette is attached;a pump which is connected to the nozzle;a controller which is configured to control an operation of the pump to cause air to be ejected from the nozzle or to be sucked into the nozzle, thereby causing the pipette to perform pipetting; anda condition inputting unit in which a user inputs a condition of control of the controller,as the condition of the control, at least one of a rate of ejection of air from the nozzle, a rate of suction of air into the nozzle, an amount of suction of air, an amount of ejection of air, a duration time of ejection of air, a duration time of suction of air, an interval between election and suction, and ejection and suction numbers being variable.2. The cell isolation apparatus according to claim 1 , further comprising a pressure sensor which is configured to sense an internal pressure of the pipette through the nozzle.3. The cell isolation apparatus according to claim 2 , wherein the controller changes the condition of the control based on the internal pressure which is sensed by the pressure sensor.4. The cell isolation apparatus according to claim 1 , further comprising a treatment solution accommodator which is configured to ...

Подробнее

Номер записи: 95

12-12-2013 дата публикации

CARRIER ENCLOSING TIP, CARRIER TREATING APPARATUS AND METHOD OF CARRIER TREATMENT

Номер: US20130330251A1

Автор: Tajima Hideji

Принадлежит: Universal Bio Research Co., Ltd.

The invention relates to a carrier enclosing tip, a carrier treating apparatus, and a method of carrier treatment. An object is to perform separation/purification more efficiently and rapidly as compared with treatments using conventional liquid chromatography or filters. There is provided a carrier enclosing tip comprising: a tip-like container having a fitting opening which is fittable to a nozzle for use in gas suction and discharge, or a member to be fitted to a nozzle, and a port through which fluid inflow and outflow can be effected by the gas suction and discharge; and a carrier which is enclosed in the tip-like container, and is capable of adsorbing a biosubstance in the fluid or is capable of reacting with or binding to the biosubstance. 1. A carrier enclosing tip comprising:a tip-like container having a fitting opening which is fittable to a nozzle for use in gas suction and discharge, or a member to be fitted to a nozzle, and a port through which fluid inflow and outflow can be effected by said gas suction and discharge; and a carrier which is enclosed in said tip-like container, and is capable of adsorbing or capturing a biosubstance in said fluid or is capable of reacting with or binding to the biosubstance,and said tip-like container is provided with an enclosing section which encloses said carrier in said tip-like container so that said carrier can be in contact with a fluid that has flown into said tip-like container,and as said enclosing section, there is provided a step which is provided projecting inward, and facing away from the port so as to partition an inner wall surface of said tip-like container between said fitting opening and said port, on the inner wall surface, at least in two points while being separated from each other, along a direction linking said fitting opening and said port,and further comprising two or more carrier passage prevention members provided separately from the tip-like container so as to partition between said port and ...

Подробнее

Номер записи: 96

19-12-2013 дата публикации

Resistance analytical furnace

Номер: US20130334198A1

Автор: Gordon C. Ford, Joshua N. Wetzel

Принадлежит: Leco Corp

A resistance furnace provides an improved upper and lower electrode construction with significantly increased coolant flow. The lower electrode has a tip design that significantly lowers the electrode tip temperature during an analysis. The upper and lower electrodes also cooperate with an improved crucible design to significantly reduce the power required to fuse a specimen contained in the crucible. The furnace uniformly heats the floor and lower side walls of a crucible, which lowers the power requirement for specimen fusion and provides higher structural benefits to provide consistent analysis and manufacturing yields. The crucible has a cylindrical body and pedestal base with an annular smoothly curved concave indentation therebetween.

Подробнее

Номер записи: 97

19-12-2013 дата публикации

CRUCIBLE

Номер: US20130337396A1

Автор: Ford Gordon C., Wetzel Joshua N.

Принадлежит:

A graphite crucible has a cylindrical body with an upper opening for receiving a sample for analysis and a disk-shaped pedestal base. The pedestal base includes a bottom surface with a centrally formed circular indentation. An inwardly projecting concave arcuate annular indentation extends between the body and pedestal base with a smoothly curved radius of curvature. The upper and lower walls of the arcuate indentation diverge outwardly at an angle of from about 56 to about 60°. The pedestal base includes a bottom surface with a centrally formed circular indentation. 1. A graphite crucible for use in a resistance analytical furnace comprising:a generally cylindrical body having a pedestal base and an inwardly concave arcuate annular indentation extending between said body and said base having a smoothly curved radius of curvature with upper and lower walls diverging at an angle of from 56° to 60°; andwherein said pedestal base is generally disk-shaped.2. The crucible as defined in wherein said annular indentation has a radius of curvature of about 0.05 inches.3. The crucible as defined in wherein said base has a bottom surface and said lower wall of said base forms an angle from said bottom surface of from 22°-24°.4. The crucible as defined in wherein said disk-shaped base has a bottom surface which includes a centrally formed circular indentation.5. The crucible as defined in wherein said circular indentation in said bottom surface of said pedestal base has a diameter of about 0.19 inches and a depth of about 0.056 inches.6. The crucible as defined in wherein said cylindrical body has a concave floor having a radius of curvature of about 0.35 inches.7. The crucible as defined in wherein said cylindrical body has a cylindrical inner wall and floor of said crucible has corners between said inner side wall and said concave floor having a radius of curvature of about 0.06 inches.8. The crucible as defined in wherein the outer diameter of said crucible body is about 0.5 ...

Подробнее

Номер записи: 98

19-12-2013 дата публикации

Extraction Pipette

Номер: US20130337577A1

Автор: David R. Pawlowski

Принадлежит: CUBRC Inc

A solid-phase extraction pipette ( 20 ) is provided for extracting substances comprising: a generally hollow body ( 29 ) having an inlet ( 21 ), a stem ( 22 ), and an elastic chamber ( 28 ); a first extraction media ( 27 ) arranged within the hollow body; and a first fit ( 24 ) contained within the hollow body and configured to prevent the first extraction media from exiting the body. The body may be made of a transparent material such as low density polyethylene. The chamber may be configured for movement from a first expanded form having a first volume to a second contracted form having a second volume less than the first volume.

Подробнее

Номер записи: 99

26-12-2013 дата публикации

Packaging structure

Номер: US20130343968A1

Автор: Yuzuru Ootsuka

Принадлежит: Fujifilm Corp

The present invention provides a packaging structure, which includes a plurality of dry analytical elements that are stacked on top of one another in a thickness direction; a packaging bag into which the dry analytical elements are placed and that is separable in two along a planar direction of the dry analytical elements; and protective sheets that are placed in between the dry analytical elements and that are each fixed, at one end, to one side of the packaging bag that is separable in two.

Подробнее

Номер записи: 100