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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 570. Отображено 100.
06-06-2013 дата публикации

Threads of cross-linked hyaluronic acid and methods of use thereof

Номер: US20130142731A1
Автор: Geoffrey C. Gurtner, Hiram Chee, Jayakumar Rajadas, Kenneth N. Horne
Принадлежит: Tau Tona Group LP

This invention relates generally to threads of hyaluronic acid, methods of making such threads and uses thereof, for example, in aesthetic applications (e.g., facial contouring, dermal fillers), surgery (e.g., sutures), drug delivery, negative pressure wound therapy, moist wound dressing, and the like.

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Номер записи: 1
07-01-2021 дата публикации

Nozzle shut off for injection molding system

Номер: US20210001532A1
Автор: Richard Ernest Fitzpatrick
Принадлежит: Extrude To Fill Inc

An injection molding apparatus and method of fabricating a molded part are provided. The apparatus may include a barrel, a nozzle enclosing an end of the barrel and defining an opening in fluid communication with an inside of the barrel, and an extrusion screw positioned at least partially inside the barrel and rotatable relative to the barrel. The extrusion screw may include a screw tip. Relative axial movement between the barrel and the extrusion screw may open or close the opening of the nozzle to permit or prevent, respectively, material flow through the opening of the nozzle. The method may include clamping a mold, opening a nozzle, rotating the extrusion screw to pump a molten material into the mold until the mold is filled, closing the nozzle, and unclamping the mold to release a molded part.

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Номер записи: 2
14-01-2021 дата публикации

Solid hair cosmetic composition

Номер: US20210007961A1
Автор: Manuela Mette, Petra Westphal, Soeren Scheele, Thomas Schroeder
Принадлежит: Henkel AG and Co KGaA

The present disclosure relates to a solid hair cosmetic composition comprising—based on the total weight of the cosmetic composition—0.1 to 40.0% by weight of at least one polysaccharide, at least one polysaccharide being starch from corn, rice, potato or tapioca; modified starch; hydroxypropyl starch phosphate or a dextrin, and optionally: 10.0 to 60.0% by weight of at least one polyhydric alcohol, 0.1 to 15.0% by weight of at least one cationic surfactant, and 0.1 to 15.0% by weight of at least one saturated or unsaturated, branched or unbranched C8-C30 alcohol and/or a saturated or unsaturated, branched or unbranched C8-C30 carboxylic acid and/or a salt of a saturated or unsaturated, branched or unbranched C8-C30 carboxylic acid, as well as production and application methods and uses thereof.

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Номер записи: 3
18-01-2018 дата публикации

Method Of Manufacturing Embedded Water Soluble Film Carrier

Номер: US20180015643A1
Автор: Patel Shilpan Pravinchandra, Saiyad Atikullah Hussainmiya
Принадлежит:

A water-soluble film (WSF) system comprises at least one active material embedded/entrapped in the film so as to provide precise and desired release of the at least one active material therefrom. The at least one active material includes detergents, enzymes, softeners, perfumes, pesticides, fungicides, active ingredients, dyes, pigments, hazardous chemicals, active agents for cleaning laundry, dishes, floorings, walls, furniture, fluffs, pulp, and combinations thereof. Online and offline processes can be used for the manufacture of multi-layered WSFs with or without liners. The WSFs can be formed in desired shapes to selectively entrap interacting/non-interacting materials and combinations thereof. The process also provides options for the use of a wide range of raw materials, liners such as paper, film, foil, fabric, etc. 1. A water soluble film (WSF) system comprising a water soluble film having at least one active material embedded/entrapped in said film at a selective concentration and depths/dispositions in said film such that the said active material thus embedded/entrapped in said film is delivered at preselected desired quantities.2. The WSF system as claimed in wherein said embedded/entrapped materials are selected active materials.3. The WSF system as claimed in wherein said active materials are selected from detergents claim 2 , enzymes claim 2 , softeners claim 2 , perfumes claim 2 , pesticides claim 2 , fungicides claim 2 , active ingredients claim 2 , dyes claim 2 , pigments claim 2 , hazardous chemicals claim 2 , active agents for cleaning laundry claim 2 , dishes claim 2 , floorings claim 2 , walls claim 2 , furniture claim 2 , and combinations thereof embedded in the WSF for delivering in precise and desired quantities.4. The WSF system as claimed in wherein said water soluble film comprises multilayered film.5. The WSF system as claimed in wherein the water soluble film is made of a material that dissolves in the presence of water and wherein the ...

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Номер записи: 4
16-01-2020 дата публикации

METHOD FOR MANUFACTURING HYALURONATE FILM, AND HYALURONATE FILM MANUFACTURED THEREBY

Номер: US20200016795A1
Автор: BANG Ji Hyun, CHOI So Mang, HA Man, HONG Ju Yeon, Kim Seul Ki, KWEON Dong Keon, Lee Young Mo, LIM Seung Taik
Принадлежит:

The present invention relates to a method of manufacturing a hyaluronate film and a hyaluronate film manufactured thereby, and more particularly to a method of manufacturing a hyaluronate film through a solvent-casting process or using an automatic film applicator that facilitates mass production and to a hyaluronate film manufactured thereby, which is useful as a mask pack for cosmetics, a patch for medicaments and medical devices, a film-type adhesion inhibitor, etc. Unlike conventional liquid products, the hyaluronate film according to the present invention has a dry surface and thus entails no concern about microbial contamination, is easy to produce/manage/distribute/use, and has superior mechanical properties, whereby it can be utilized for various applications such as packs, patches, artificial skin and the like for cosmetics, medicaments, and medical devices. 1. A method of manufacturing a hyaluronate film , the method comprising:(a) preparing a hyaluronate solution by dissolving hyaluronate in a solvent; and(b) drying the hyaluronate solution through a solvent-casting process or a casting process using an automatic film applicator.2. The method of claim 1 , wherein the solvent-casting process includes:(a) preparing a 0.1 to 30 wt % hyaluronate solution by dissolving hyaluronate in a solvent; and(b) placing the hyaluronate solution in a mold and drying the hyaluronate solution under conditions of a relative humidity of 30 to 70% and a drying temperature of 30 to 50° C.3. The method of claim 2 , wherein the hyaluronate has a molecular weight of 0.1 to 2.5 MDa.4. The method of claim 2 , wherein the solvent is water or a 0.01 to 29 vol % ethanol aqueous solution.5. The method of claim 2 , wherein the drying the hyaluronate solution is performed using a constant-temperature and constant-humidity chamber.6. The method of claim 1 , wherein the casting process using the automatic film applicator includes:(a) preparing a 0.1 to 30 wt % hyaluronate solution by ...

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Номер записи: 5
22-01-2015 дата публикации

STRIP-FORM WC CLEANING PRODUCT

Номер: US20150020330A1
Автор: Cappleman Robert Stephen, Ebrahimzadeh Keiwan, Hochkugler Sabine, HORN Michael, Plantikow Petra, Reichert Christian, Schiedel Marc-Steffen
Принадлежит:

A strip-form toilet cleaning product comprising a width (B), a height (H) and a thickness (S), wherein the ratio between width (B), height (H) and thickness (S) is between 1:1:0.01 and 1:0.1:0.2, a first extruded phase and at least one second extruded phase, wherein at least the contour of a contact surface () along the center axis () takes the form of a sine wave which has an amplitude of A, wherein the ratio of amplitude to width (B) A:B amounts to between 1:10 and 1:25 and the periodic length of the sine wave corresponds to 0.1-1 times the width (B) of the toilet cleaning product. 1. A strip-form toilet cleaning product for application in the interior of a toilet bowl comprisinga width (B), a height (II) and a thickness (S), wherein the ratio between width (B), height (H) and thickness (S) is between 1:1:0.01 and 1:0.1:0.2,a first extruded phase andat least one second extruded phase, wherein the first phase differs from at least the second phase, wherein however all the phases comprise at least one adhesion promoter at least on the side of the toilet cleaning product to be applied onto the toilet bowl andthe first phase and at least the second phase have a contact surface with one another wherein{'sub': 1,O', '1,O, 'at least the contour of a contact surface along the center axis takes the form of a sine wave which has an amplitude of A, wherein the ratio of amplitude to width (B) A:B amounts to between 1:10 and 1:25 and the periodic length of the sine wave corresponds to 0.1-1 times the width (B) of the toilet cleaning product.'}2. The strip-form toilet cleaning product according to claim 1 , characterized in that the first phase and the at least second phase have the same width (B).3. The strip-fond toilet cleaning product according to claim 1 , characterized in that the first phase and at least the second phase have substantially the same height.4. The strip-form toilet cleaning product according to claim 1 , characterized in that the first phase and at least ...

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Номер записи: 6
10-02-2022 дата публикации

Polymer latex and layered product

Номер: US20220041844A1
Автор: Kentaro Hayasaka, Takashi Iga
Принадлежит: Zeon Corp

A polymer latex including a polymer and at least one polysaccharide selected from the group consisting of tamarind gum, xanthan gum, cationized xanthan gum, gellan gum, guar gum and cationized guar gum.

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Номер записи: 7
01-02-2018 дата публикации

NOZZLE SHUT OFF FOR INJECTION MOLDING SYSTEM

Номер: US20180029262A1
Автор: Fitzpatrick Richard Ernest
Принадлежит: EXTRUDE TO FILL, LLC

An injection molding apparatus and method of fabricating a molded part are provided. The apparatus may include a barrel, a nozzle enclosing an end of the barrel and defining an opening in fluid communication with an inside of the barrel, and an extrusion screw positioned at least partially inside the barrel and rotatable relative to the barrel. The extrusion screw may include a screw tip. Relative axial movement between the barrel and the extrusion screw may open or close the opening of the nozzle to permit or prevent, respectively, material flow through the opening of the nozzle. The method may include clamping a mold, opening a nozzle, rotating the extrusion screw to pump a molten material into the mold until the mold is filled, closing the nozzle, and unclamping the mold to release a molded part. 1. A method of molding a part , comprising:rotating a screw within a barrel to extrude a molten material through a nozzle opening of a nozzle into a mold cavity; andafter extruding the molten material through the nozzle opening, inserting a cylindrical tip portion of the screw corresponding in geometry to the nozzle opening into the nozzle opening along an entire axial length of the nozzle opening to displace all of the molten material from the nozzle opening.2. The method of claim 1 , wherein inserting the tip portion of the screw into the nozzle opening comprises inserting the tip portion of the screw into the nozzle opening until the tip portion of the screw is substantially flush with an exterior surface of the nozzle.3. The method of claim 1 , wherein inserting the tip portion of the screw into the nozzle opening comprises sealingly engaging the tip portion of the screw with the nozzle along the entire axial length of the nozzle opening.4. The method of claim 1 , further comprising sealingly engaging an interior surface of the nozzle with a transition portion of the screw.5. The method of claim 4 , wherein the transition portion of the screw extends outward from the ...

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Номер записи: 8
05-02-2015 дата публикации

SCAFFOLD AND METHOD OF FORMING SCAFFOLD BY ENTANGLING FIBRES

Номер: US20150034242A1
Автор: Wan Andrew C. A., Ying Jackie Y.
Принадлежит:

A porous scaffold is provided, which comprises tangled fibres. A porous scaffold can be formed by applying a fluid to fibres to entangle them. The fibres comprise a polyelectrolyte complex and a cross-linker. The cross-linker links polyelectrolytes within individual fibres and inhibits secondary polyelectrolyte complication between adjacent fibres. 1. A method of forming a porous scaffold , comprising the steps of:providing fibres comprising polyelectrolytes forming a polyelectrolyte complex, said fibres further comprising a cross-linker linking said polyelectrolytes within individual ones of said fibres for inhibiting secondary polyelectrolyte complexation between adjacent fibres; andapplying a fluid to said fibres to entangle said fibres to form a porous structure.2. The method of claim 1 , wherein said cross-linker comprises silicon.3. The method of claim 2 , wherein said cross-linker links said polyelectrolytes through Si—O bonds.4. The method of claim 2 , wherein said cross-linker comprises silica.5. The method of claim 1 , wherein said cross-linker is selected from acrylates claim 1 , succinimides claim 1 , carbodiimides claim 1 , and quinones.6. The method of claim 1 , wherein said polyelectrolytes are selected from alginate claim 1 , chitosan claim 1 , chitin claim 1 , heparin claim 1 , chondroitin sulfate claim 1 , hyaluronic acid claim 1 , DNA claim 1 , RNA claim 1 , poly(ornithic acid) claim 1 , polyacrylic acid claim 1 , poly(ethyleneimine) claim 1 , gellan claim 1 , carboxylated polymer claim 1 , aminated polymer claim 1 , chitosan derivative claim 1 , chitin derivative claim 1 , acrylate polymer claim 1 , nucleic acid claim 1 , histone protein claim 1 , acidic polysaccharide claim 1 , derivative of acidic polysaccharide claim 1 , poly(amino acid) claim 1 , poly(lysine) claim 1 , and poly(glutamic acid).7. The method of claim 6 , wherein said polyelectrolyte complex is selected from alginate-chitosan claim 6 , heparin-chitosan claim 6 , chondroitin ...

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Номер записи: 9
11-02-2016 дата публикации

METHOD AND APPARATUS FOR PELLETIZING BIOMATERIAL COMPOSITES

Номер: US20160039124A1
Автор: MANN ROBERT G., MARTIN J. WAYNE, WRIGHT ROGER B.
Принадлежит: GALA INDUSTRIES, INC.

A process for preparing low moisture content polymer biomaterial composites and expandable polymer biomaterial composites by extrusion through a die plate into a waterbox and pelletizing with cutter blades. Polyolefins or condensation polymers are melt blended with a solid or semi-solid biomaterial component, such as polysaccharides, including cellulosics and starches, or proteinaceious materials, including polypeptides, and are extruded, pelletized underwater, and processed with accelerated drying to achieve moisture levels as low as one percent or less. 1. A method for processing polymer biomaterial composites into pellets using a pelletizing apparatus including an underwater pelletizer , piping to introduce water into said pelletizer , a slurry line to transport a water and pellet slurry out of said pelletizer , and an injector for introducing a high velocity gas into said slurry line , said method including the steps of extruding strands of a polymer biomaterial composite through a die plate into said underwater pelletizer , cutting the composite strands into polymer biomaterial composite pellets in said pelletizer , transporting said polymer biomaterial composite pellets from said pelletizer as a water and pellet slurry in said slurry line , and injecting a high velocity inert gas into said water and pellet slurry through said injector to cause said water to aspirate from said polymer biomaterial composite pellets and said pellets to retain internal heat , to reduce moisture uptake by said polymer biomaterial composite pellets , and to expedite transport and drying of said pellets.2. The method as claimed in claim 1 , wherein the drying of said polymer biomaterial composite pellets achieves a moisture level approaching 1%.3. The method as claimed in claim 1 , further comprising transporting said pellets into a dryer after said high velocity inert gas is injected into said water and pellet slurry.4. The method claim 3 , as claimed in claim 3 , further comprising ...

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Номер записи: 10
19-02-2015 дата публикации

ACID RESISTANT CAPSULES

Номер: US20150050334A1
Автор: Cade Dominique Nicolas, He Xiongwei David
Принадлежит:

The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer. 115-. (canceled)16. An aqueous composition comprising an aqueous solvent , gellan gum , and at least one water-soluble , film forming polymer , wherein the weight ratio of gellan gum to said at least one water soluble , film forming polymer is ranges from about 4/100 to about 15/100 , and wherein the composition does not comprise additional gelling aids.17. The aqueous composition according to claim 16 , further comprising at least one additive selected from the group consisting of inert claim 16 , non-toxic pharmaceutical grade or food grade pigments claim 16 , plasticizers claim 16 , surfactants claim 16 , and flavouring agents.18. The aqueous composition according to claim 16 , wherein the at least one water soluble film forming polymer is selected from the group consisting of HPMC claim 16 , gelatine claim 16 , pullulan claim 16 , PVA hydroxypropyl starch claim 16 , and mixtures thereof.19. The aqueous composition according to claim 18 , wherein the at least one water-soluble film forming polymer is selected from the group consisting of HPMC claim 18 , gelatin and mixtures thereof.20. The aqueous composition according to claim 19 , wherein the at least one water-soluble film forming polymer is HPMC.21. The aqueous composition according to claim 16 , wherein the ratio of gellan gum ranges from about 4.5/100 to about 6/100 parts by weight of the at least one water soluble film forming polymer.22. The aqueous composition according to claim 16 , ...

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Номер записи: 11
25-02-2016 дата публикации

POLYSACCHARIDE FILM AND METHOD FOR THE PRODUCTION THEREOF

Номер: US20160053061A1
Автор: Beiter Elisabeth, Dürnberger Franz, Kroner Gert, Riedl Gerold, Schweigart Andreas
Принадлежит: Lenzing AG

The present invention relates to a method for the production of films made of polysaccharides which, as a fiber-forming substance, contain α(1→3)-glucan, as well as to the films made thereof and to their use. 1. A method for the production of a polysaccharide film , wherein the finished spinning solution for the extrusion comprises an amine oxide , at least 23% by weight of water , related to the total quantity of the spinning solution , and , as a polysaccharide , α(1→3)-glucan.2. The method according to claim 1 , wherein the amine oxide is N-methylmorpholine-N-oxide.3. The method according to claim 1 , wherein at least 90% of the α(1→3)-glucan consist of hexose units and at least 50% of the hexose units are linked via α(1→3)-glycosidic bonds.4. The method according to claim 1 , wherein the extrusion is carried out by means of a straight slot die or an annular slot die.5. The method according to in claim 1 , wherein the spinning solution is stretched following the extrusion.6. A polysaccharide film comprising a film-forming substance claim 1 , wherein the film-forming substance consists substantially of α(1→3)-glucan.7. The polysaccharide film according to claim 6 , wherein at least 90% of the α(1→3)-glucan consist of hexose units and at least 50% of the hexose units are linked via α(1→3)-glycosidic bonds.8. The polysaccharide film according to claim 6 , wherein the film is oriented at least in one dimension. The present invention relates to a method for the production of films made of polysaccharides which, as a fiber-forming substance, contain □(1□3)-glucan, as well as to the films made thereof and to their use. For the purposes of the present invention, the terms “film” and “sheet” shall be used as being synonymous.Polysaccharides are becoming increasingly important, as they are materials that can be obtained from renewable raw materials. One of the most frequently occurring polysaccharides is cellulose. Cotton fibers, which consist almost exclusively of ...

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Номер записи: 12
26-02-2015 дата публикации

METHOD TO MINIMIZE MOLECULAR WEIGHT DROP OF POLY(L-LACTIDE) STENT DURING PROCESSING

Номер: US20150054202A1
Автор: Lambert Byron, Oberhauser James, Wang Yunbing
Принадлежит:

A method to reduce or minimize the reduction in molecular weight of a stent during processing is disclosed. The stent has a scaffolding including a polymer formulation comprising PLLA and polymandelide. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing. 1. (canceled)2. A method of fabricating a bioabsorbable polymer stent comprising:fabricating a polymer tube with extrusion comprising a polymer formulation;forming a stent scaffolding from the polymer tube; andsterilizing the stent scaffolding by exposing the stent scaffolding to a dose of e-beam radiation between 25-50 kGy,wherein a drop in weight average molecular weight (Mw) of the polymer formulation from extrusion to sterilization is less than 50%.3. The method of claim 2 , wherein the drop in Mw of the polymer formulation from extrusion to sterilization is less than 30%.4. The method of claim 2 , wherein the drop in Mw of the polymer formulation from extrusion to sterilization is less than 20%.5. The method of claim 2 , wherein a Mw of the polymer formulation of the sterilized stent scaffolding is at least 120 kg/mol.6. The method of claim 2 , wherein the dose of e-beam radiation is greater than 30 kGy.7. The method of claim 2 , wherein the polymer formulation comprises poly(L-lactide) (PLLA) and polymandelide claim 2 , the polymandelide reducing the molecular weight reduction of the PLLA due to the exposure.8. The method of claim 7 , wherein the stent scaffolding comprises between 2-5 wt % the polymandelide.9. The method of claim 2 , wherein the polymer formulation comprises a blend of PLLA and polymandelide.10. The method of claim 2 , wherein the polymer formulation comprises a block copolymer of the PLLA and polymandelide.11. The method of claim 10 , wherein the polymandelide blocks are between 2-5 wt % ...

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Номер записи: 13
03-03-2016 дата публикации

MIMETIC TISSUE STRUCTURE CONTAINING EXTRACELLULAR MATRIX PROTEIN-BONE MINERAL COMPLEX AND METHOD FOR MANUFACTURING SAME

Номер: US20160058909A1
Автор: Chung Chong-Pyoung, Lee Jue-Yeon, Park Yoon Jeong
Принадлежит:

Provided are a tissue structure mimetic used for regenerating a tissue and a method for manufacturing the same, and more particularly, a 3-dimensional tissue structure mimetic which consists of a complex of extracellular matrix protein and bone mineral, wherein the complex is specifically bound to a regeneration-functional peptide to thereby be capable of implementing environment of a tissue requiring restoration, and a method for manufacturing the same. In the tissue structure mimetic according to the present invention, bone mineral components are finely dispersed in the extracellular matrix protein to have excellent mechanical strength of the tissue structure mimetic and conductivity which provides a migration path of cells involved in tissue regeneration. Further, environment of the tissue may be implemented by the peptide contained in the tissue structure mimetic to finally remarkably increase tissue regeneration capacity. 1. A method for manufacturing a tissue structure mimetic which consists of a complex of extracellular matrix protein and bone mineral , the method comprising the steps of:(a) injecting a mixture of extracellular matrix protein and micro-sized bone mineral particles into a predetermined size of a forming mold;(b) repeating rapid-freezing and thawing thereby aligning a structure of protein;(c) crosslinking by adding a monosaccharide solution; and(d) performing lyophilization.2. The method of claim 1 , wherein the extracellular matrix protein is at least one selected from the group consisting of collagen claim 1 , hyaluronic acid claim 1 , elastin claim 1 , chondroitin sulfate claim 1 , and fibroin.3. The method of claim 1 , wherein the bone mineral component is at least one selected from the group consisting of bio-derived bone mineral powders that are derived from allograft claim 1 , bovine bone claim 1 , equine bone claim 1 , swine bone claim 1 , synthetic hydroxide apatite claim 1 , and tricalcium phosphate micro powders.4. The method of ...

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Номер записи: 14
03-03-2016 дата публикации

COMPOSITION FOR THE PREPARATION OF A NANOSTRUCTURED BIODEGRADABLE POLYMERIC MATERIAL, THE MATERIAL OBTAINED AND ITS APPLICATIONS

Номер: US20160060453A1
Автор: Aucejo Romero Susana, GALET DOMINGO Ana, Gallur Blanca Miriam, Hortal Ramos Mercedes, Jordá Beneyto María, ORTUÑO MANSILLA Natalia
Принадлежит:

The composition comprises a mixture of: i) poly(L-, D-lactide) homopolymer and, optionally, poly(ε-caprolactone) homopolymer, and ii) poly(L-lactide) and poly(ε-caprolactone) diblock copolymer, where said copolymer has a molar mass of the L-lactide block of 20,000 g/mol to 200,000 g/mol and a molar mass of the ε-caprolactone block of 10,000 g/mol to 100,000 g/mol, with the molar ratio between the L-lactide block and the ε-caprolactone block of 2:1. The invention also refers to the nanostructured material obtained from this composition that is characterised by a nanostructure of two mutually self-assembled phases, one phase being formed by a polymeric matrix of poly(L-, D-lactide) units and the other phase by poly(ε-caprolactone) units self-assembled with the matrix and also its use for the manufacture of a plastic article in the form of a transparent film or thin sheet. 1. Biodegradable composition for the preparation of a nanostructured biodegradable polymeric material , characterised in that it comprises a mixture of:i) poly(L-, D-lactide) homopolymer (PLA) and, optionally, poly(ε-caprolactone) homopolymer (PCL), andii) poly(L-lactide) and poly(ε-caprolactone) diblock copolymer (CPB), wherein this copolymer has a molar mass of the L-lactide block of between 20,000 g/mol and 200,000 g/mol and a molar mass of the ε-caprolactone block of between 10,000 g/mol and 100,000 g/mol, with the molar ratio between the L-lactide block and the ε-caprolactone block being 2:1.2. Biodegradable composition of wherein the poly(ε-caprolactone) block of the copolymer is in a concentration of between 10% and 90% claim 1 , preferably between 20% and 80% claim 1 , and still more preferably between 20% and 40% of the weight of the poly(L- claim 1 , D-lactide) homopolymer (PLA).3. Biodegradable composition of comprising a mixture of:i) poly(L-, D-lactide) homopolymer (PLA) and poly(ε-caprolactone) homopolymer (PCL) andii) poly(L-lactide) and poly(ε-caprolactone) diblock copolymer (CPB), ...

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Номер записи: 15
17-03-2022 дата публикации

METHOD OF REINFORCEMENT FOR KERATIN MATERIALS

Номер: US20220080628A1
Автор: Mu Bingnan, Yang Yiqi
Принадлежит:

A method for preparing keratin-based composites includes mixing polysaccharide nanoparticles and a keratin solution to form a nanoparticle-keratin solution; and solvent casting the nanoparticle-keratin solution to form the keratin-based composites. 1. A method for preparing keratin-based composites , comprising:(i) mixing polysaccharide nanoparticles and a keratin solution to form a nanoparticle-keratin solution; and(ii) solvent casting the nanoparticle-keratin solution to form the keratin-based composites.2. The method of claim 1 , wherein the concentration of nanoparticles in the nanoparticle-keratin solution is from about 1% to about 5%.3. The method of claim 1 , wherein the polysaccharide nanoparticles have an average particle size of about 80 nm to about 500 nm.4. The method of claim 1 , wherein the polysaccharide nanoparticles comprise natural polysaccharides comprising one or more hydroxyl groups claim 1 , aldehyde groups claim 1 , amino groups claim 1 , carboxyl groups claim 1 , or derivatives thereof.5. The method of claim 1 , wherein the polysaccharide nanoparticles comprise chitin claim 1 , sodium alginate claim 1 , carboxymethyl cellulose claim 1 , or combinations thereof.6. The method of claim 1 , wherein the polysaccharide nanoparticles are chitin nanoparticles.7. The method of claim 6 , wherein the chitin nanoparticles have a degree of deacetylation about 5% to about 60%.8. The method of claim 6 , wherein the chitin nanoparticles are prepared by a process comprising:treating chitin with an acid to form an acid hydrolyzed chitin; andtreating the acid hydrolyzed chitin with an alkali solution.9. The method of claim 8 , wherein the acid comprises hydrochloric acid claim 8 , sulfuric acid claim 8 , or a combination thereof.10. The method of claim 8 , wherein the alkali solution comprises sodium hydroxide claim 8 , potassium hydroxide claim 8 , or a combination thereof.11. The method of claim 1 , wherein the keratin solution has a concentration of from ...

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Номер записи: 16
24-03-2016 дата публикации

TRANSPLANTATION DEVICE AND METHOD OF USE

Номер: US20160082236A1
Автор: Botvinick Elliot L., George Steven C., Lakey Jonathan R. T., Shergill Bhupinder S.
Принадлежит:

Embodiments of the present disclosure relates to an implantable structure and a two stage method for cell and/or tissue transplantation. The implantable structure is configured to promote vascularization prior to cell and/or tissue transplantation, thereby allowing for implanted cells and/or tissues to have increased viability. In some embodiments, oxygen sensitive dyes can be used to determine levels of vascularization of the device. 1. A device for cell transplantation comprising:a biocompatible frame configured to be inserted into tissue;at least one slit passing through the frame, wherein the at least one slit is sized and configured to allow vascular perfusion through the at least one slit; anda fluidic channel located within the frame and comprising a semipermeable surface region configured to retain cells while allowing certain dissolved molecules to diffuse between the fluidic channel and the at least one slit.2. The device of claim 1 , further comprising at least one inlet/outlet port in fluid communication with the fluidic channel.3. The device of claim 2 , wherein the at least one inlet/outlet port is configured to be sealed.4. The device of claim 1 , wherein the fluidic channel is configured to retain islet cells.5. The device of claim 1 , wherein the frame is formed from a plurality of layers bonded together.6. The device of claim 1 , wherein the frame is monolithic.7. The device of claim 1 , wherein the frame is a hydrogel.8. The device of claim 1 , wherein the frame is formed from a material selected from the group consisting of alginate claim 1 , polydimethylacrylamide (PDMA) claim 1 , polydimethylsiloxane (PDMS) claim 1 , polyacrylonitrile (PAN) or polymethylmethacrylate (PMMA).9. The device of claim 1 , further comprising a plurality of slits.10. The device of claim 1 , further comprising a plurality of fluidic channels.11. The device of claim 1 , wherein the semipermeable surface region of the fluidic channel comprises dialysis tubing.12. The ...

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Номер записи: 17
31-03-2022 дата публикации

Fibres, a process for producing such fibres and a wound dressing incorporating them

Номер: US20220096704A1
Автор: Alan Rogers, Lucy Louisa Ballamy, Marion Herbe, Sean Kelly, Sharon Lam Po Tang
Принадлежит: Convatec Technologies Inc

Multi component fibres for the reduction of the damaging activity of wound exudate components such as protein degrading enzymes and inflammatory mediators in wounds, the fibres comprising: from 10% to 100% by weight of the fibres of pectin and a sacrificial proteinaceous material in a weight ratio of 100:0 to 10:90 pectin to sacrificial proteinaceous material and from 0% to 90% by weight of the fibres of another polysaccharide or a water soluble polymer.

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Номер записи: 18
23-03-2017 дата публикации

Implantable biocompatible reactor

Номер: US20170081626A1
Автор: Abdelkader Zebda, Donald K. MARTIN, Philippe Cinquin, Sarra EL ICHI
Принадлежит: UNIVERSITE GRENOBLE ALPES

The invention concerns a bioreactor obtained by compressing a mixture of an enzyme, a conductor and chitosan. The conductor can consist of carbon nanotubes. This bioreactor can be produced according to the following steps: preparing a mixture of powders in which the proportion of enzyme powder relative to a carbon nanotube powder is of the order of 50/50 by weight; preparing a viscous solution of chitosan in a ratio of 5 to 15 (in mg) of chitosan to 0.75 to 1.25 (in ml) of acetic acid diluted to 0.4 to 0.6% by volume in water; adding the viscous chitosan to the mixture of powders in a proportion be weight of 3 to 5 of powder to 5 to 10 of chitosan; carrying out a first compression followed by light grinding; carrying out a second compression to produce a pellet; and drying at ambient temperature.

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Номер записи: 19
02-04-2015 дата публикации

Smooth 3D Printing Using Multi-Stage Filaments

Номер: US20150091200A1
Автор: Mech Radomir
Принадлежит: ADOBE SYSTEMS INCORPORATED

This document describes techniques and apparatuses for smooth 3D printing using multi-stage filaments. These techniques are capable of creating smoother surfaces than many current techniques. In some cases, the techniques determine a portion of a surface of a 3D object that includes, or will include, a printing artifact or is otherwise not smooth, and then applies multi-stage filaments to provide a smoothing surface over that portion. 1. A method comprising:determining that a portion of a surface of a three-dimensional (3D) object includes a multi-stage 3D production artifact; andproviding, over the portion of the surface, a smoothing surface having one or more filaments, at least one of the one or more filaments provided over two or more stages of the multi-stage 3D production artifact.2. The method of claim 1 , wherein the determining is performed prior to printing the 3D object claim 1 , the determining based on a model of the 3D object.3. The method of claim 1 , wherein the determining is based at least in part on a physical characteristic of a filament head intended to apply the one or more filaments of the smoothing surface.4. The method of claim 1 , wherein the determining determines that the multi-stage 3D production artifact includes support-to-support distances over which the one or more filaments are to be provided that are greater than a maximum droop distance of a planned application angle of the one or more filaments and further comprising:increasing the maximum droop distance of the one or more filaments by increasing a viscosity of a filament material;providing, prior to providing the smoothing surface, support structures between supports having the support-to-support distances that are greater than the maximum droop distance, the support structures effective to reduce the support-to-support distance to less than or equal to the maximum droop distance;altering a speed of application of the one or more filaments; oraltering the planned application ...

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Номер записи: 20
21-03-2019 дата публикации

Synthetic tissue structures for electrosurgical training and simulation

Номер: US20190085162A1
Автор: Eduardo Bolanos, Natasha FELSINGER, Sam Chehayeb
Принадлежит: Applied Medical Resources Corp

A surgical simulator for electrosurgical training and simulation is provided. The surgical simulator includes one or more simulated tissue structures made substantially of a hydrogel comprising a dual interpenetrating network of ionically cross-linked alginate and covalently cross-linked acrylamide. Combinations of different simulated tissue structures define procedural-based models for the practice of various electrosurgical procedures including laparoscopic total mesorectal excision, transanal total mesorectal excision, cholecystectomy and transanal minimally invasive surgery. Methods of making the simulated tissue structures are also provided.

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Номер записи: 21
12-05-2022 дата публикации

A FISHING BAIT, A MOULDABLE COMPOSITION FOR MANUFACTURING THE FISHING BAIT, A METHOD FOR MANUFACTURING THE FISHING BAIT AND A USE OF THE MOULDABLE COMPOSITION

Номер: US20220142131A1
Автор: DICK Eberhard, GÖTTLING Sonja, KOKKONEN Jari, SIIRTOLA Juha, WIRTH Sigrid
Принадлежит:

The present invention relates to a fishing bait, a mouldable composition for manufacturing the fishing bait, a method for manufacturing the fishing bait and a use of the mouldable composition. The mouldable composition comprises a basic solution comprising water, a gelling agent and a plasticizer. The mouldable composition further comprises at least one cross-linking agent in the volume of the basic solution. 1. A method for manufacturing a fishing bait comprisingforming a basic solution comprising water, gelatine and sugar alcohol at a temperature of at least 70° C., the basic solution having a volume,boiling the basic solution,evaporating water under negative pressure in order to adjust the dry matter content of the basic solution,forming a mouldable composition by adding a cross-linking agent to the volume of the basic solution after water has been evaporated from the basic solution, andpouring the mouldable composition into at least one mould to form the fishing bait.2. The method according to claim 1 , wherein the method comprises adding at least one additive for attracting fishes to the basic solution.3. The method according to claim 1 , wherein the method comprises adding fibers to the basic solution.4. The method according to claim 1 , wherein the method comprises cooling the fishing bait into ambient temperature.5. A fishing bait having the water content of 10 to 15 wt.-% claim 1 , the fishing bait comprising a basic solution comprising water claim 1 , gelatine and sugar alcohol claim 1 , the basic solution having a volume claim 1 , and at least one cross-linking agent in the volume of the basic solution.6. The fishing bait according to claim 5 , wherein the basic solution comprises glucose syrup.7. The fishing bait according to claim 5 , wherein gelatine has a mean molecular weight of at least 120 kDa claim 5 , preferably at least 130 kDa and more preferably 140 kDa.8. The fishing bait according to claim 5 , wherein the cross-linking agent comprises a ...

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Номер записи: 22
05-05-2016 дата публикации

FIBRES, A PROCESS FOR PRODUCING SUCH FIBRES AND A WOUND DRESSING INCORPORATING THEM

Номер: US20160121013A1
Автор: Ballamy Lucy Louisa, Herbe Marion, Kelly Sean, Lam Po Tang Sharon, Rogers Alan
Принадлежит: ConvaTec Technologies Inc.

Multi component fibres for the reduction of the damaging activity of wound exudate components such as protein degrading enzymes and inflammatory mediators in wounds, the fibres comprising: from 10% to 100% by weight of the fibres of pectin and a sacrificial proteinaceous material in a weight ratio of 100:0 to 10:90 pectin to sacrificial proteinaceous material and from 0% to 90% by weight of the fibres of another polysaccharide or a water soluble polymer. 1. Multi component fibres for the reduction of the damaging activity of wound exudate components such as protein degrading enzymes and inflammatory mediators in wounds , the fibres comprising:from 10% to 100% by weight of the fibres of pectin and a sacrificial proteinaceous material in a weight ratio of 80:20 to 60:40 pectin to sacrificial proteinaceous material andfrom 0% to 90% by weight of the fibres of another polysaccharide or a water soluble polymer.2. Multi component fibres as claimed in wherein the fibres comprise 75% to 100% by weight of the fibres of pectin and a sacrificial proteinaceous material in a weight ratio of 80:20 to 60:40 pectin to sacrificial proteinaceous material.3. Multi component fibres as claimed in wherein the fibres comprise 90% to 100% by weight of the fibres of pectin and a sacrificial proteinaceous material in a weight ratio of 80:20 to 60:40 pectin to sacrificial proteinaceous material4. Multi component fibre as claimed in wherein the weight ratio of pectin to sacrificial proteinaceous material in the fibres is 70:30.5. A wound dressing comprising multi component pectin fibres for use in the reduction of the damaging activity of wound exudate components such as protein degrading enzymes and inflammatory mediators in wounds.6. A wound dressing comprising multi component fibres for the reduction of the damaging activity of wound exudate components such as protein degrading enzymes and inflammatory mediators in wounds claim 1 , the fibres comprising:from 10% to 100% by weight of the ...

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Номер записи: 23
05-05-2016 дата публикации

Composition, preparation, and use of chitosan shards for biomedical applications

Номер: US20160121021A1
Автор: Andrew Crofton, Samuel M. Hudson, Wolff M. Kirsch
Принадлежит: LOMA LINDA UNIVERSITY, North Carolina State University

A thin chitosan-based material can be used for biomedical applications. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan material. A single or multiple such treatments may be employed. For example, the chitosan material may be irradiated under nitrogen using γ-irradiation, treated under a nitrogen plasma, or both. A thin chitosan material can be readily treated by surface modifying treatments such as irradiating under nitrogen using γ-irradiation, treating under a nitrogen plasma, or both.

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Номер записи: 24
12-05-2016 дата публикации

POLYSTYRENE AND POLYLACTIC ACID BLENDS

Номер: US20160130430A1
Автор: DA COSTA Joao Manoel, DAL PIZZOL Marcus Fernando, DE CARVALHO PERES Augusto Cesar, GALHARD GRASSI Vinicius, LIBERATO PETZHOLD Cesar, OSSIG Andreia
Принадлежит:

Polymeric blends of polystyrene (PS) and polylactic acid (PLA) are described, in the preparation of which a compatibilizing agent was added, preferably a PS-PLA block copolymer. Such compatibilizing agents act controlling phase separation of the blending compounds, and preventing excessive growth of polystyrene domains scattered in the PLA matrix; and this results in blends with good mechanical and thermal resistance. 1. A polystyrene and polylactic acid blend , characterized by having:a) a mixture of polystyrene (PS)/polylactic acid (PLA), where the polystyrene has a concentration from 70% m/m to 30% m/m, and the PLA has a concentration from 30% m/m to 70% m/m; andb) PS-PLA block copolymer in concentrations of 0.1% to 15% in relation to the mixture of polystyrene/PLA.2. The polystyrene and polylactic acid blend according to claim 1 , wherein the polystyrene is in concentrations from 60% m/m to 40% m/m in the mixture of polystyrene/polylactic acid.3. The polystyrene and polylactic acid blend according to claim 1 , wherein the polylactic acid concentrations are in the range from 40% m/m to 60% m/m in the mixture of polystyrene/poly-lactic acid.4. The polystyrene and polylactic acid blend according to claim 1 , wherein the PS-PLA copolymer is in concentrations from 3% m/m to 12% m/m in relation to the mixture of polystyrene/polylactic acid.5. The polystyrene and polylactic acid blend according to claim 1 , wherein the PS-PLA copolymer concentrations are from 5% m/m to 10% m/m in relation to the mixture of polystyrene/polylactic acid.6. The polystyrene and polylactic acid blend according to claim 1 , wherein the polystyrene in the polystyrene/polylactic acid mixture is a high-impact polystyrene (HIPS) based on a styrene-based polymeric matrix and claim 1 , scattered in this matrix claim 1 , there is a rubber phase compound of discrete particles of butadiene and/or styrene butadiene copolymer-based rubber with different microstructures (cis claim 1 , trans and vinyl.)7. ...

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Номер записи: 25
19-05-2016 дата публикации

SYSTEM TO PREVENT STENT DAMAGE CAUSED BY LASER CUTTING

Номер: US20160136875A1
Автор: Atladottir Svava Maria, Gale David C., Kleine Klaus, Wang Yunbing
Принадлежит:

Apparatus, method and system for cutting a polymeric stent including the use of a polymeric mandrel as a laser shielding device. The polymeric mandrel is allowed to roll freely within a polymeric tube that is cut into a polymeric stent.

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Номер записи: 26
30-04-2020 дата публикации

METHOD OF MANUFACTURING CELL SPHEROID USING THREE-DIMENSIONAL PRINTING METHOD

Номер: US20200131471A1
Автор: DAS Sanskrita, HWANG Dong Gyu, Jang Jinah, PARK Yejin, YONG UiJung
Принадлежит:

The present invention relates to a method of manufacturing a cell spheroid using three-dimensional bio-printing technology, and the cell spheroid may be used for preventing or treating vascular and endocrine diseases by including mesenchymal stem cells, induced pluripotent stem cells-derived cells, or the like as an active ingredient, or may be used as an in vitro drug testing model. 1. A method of manufacturing a cell spheroid using a three-dimensional printing method , comprisingpreparing a bioink comprising cells, decellularized extracellular matrix and alginate; andmanufacturing a cell spheroid by printing the bioink using the three-dimensional printing in a micro-extrusion manner.2. The method of manufacturing according to claim 1 , wherein manufacturing the spheroid comprisesinserting an nozzle to a mixed solution comprising a gelling agent of the alginate and hydrogel;extruding the bioink by applying a pneumatic pressure; andpulling out the injection nozzle from the mixed solution.3. The method of manufacturing according to claim 2 , further comprising applying high viscosity to the hydrogel by heating the mixed solution.4. The method of manufacturing according to claim 2 , wherein the mixed solution has enough high viscosity to form the cell spheroid by separating the extruded bioink from the injection nozzle with pulling out the injection nozzle.5. The method of manufacturing according to claim 1 , wherein the bioink is printed by being extruded at a pneumatic pressure of 30 kPa to 40 kPa.6. The method of manufacturing according to claim 1 , wherein the bioink comprises a decellularized extracellular matrix solution at a concentration of 0.5 to 5% by weight claim 1 , and an alginate solution at a concentration of 0.5 to 5% by weight.7. The method of manufacturing according to claim 1 , wherein the alginate concentration of the bioink is equal to or more than the concentration of the decellularized extracellular matrix of the bioink.8. The method of ...

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Номер записи: 27
15-09-2022 дата публикации

SMOKING DEVICE COMPRISING AT LEAST ONE BREAKABLE FLAVOURING CAPSULE

Номер: US20220287359A1
Автор: COMES FRANCHINI Mauro, MONACO Ilaria, SAETTONE Paolo
Принадлежит:

A smoking device including a tubular element containing tobacco and a filtering element connected to an end of the tubular element. The filtering element includes at least one breakable flavouring capsule which includes at least one core having at least one lipophilic substance and at least one flavouring agent dispersed or dissolved in the lipophilic substance; at least one breakable coating which coats the core and which has at least one chitosan having a weight average molecular weight (Mw) between 25 kDa and 400 kDa. Preferably, the breakable coating further includes at least one polyhydroxyalkanoate (PHA). The frangible coating that coats the core is able to preserve its hardness, and therefore its breakability, during use by the smoker, i.e. in the presence of humidity and heat that develop from the combustion of tobacco. 1. A smoking device comprising a tubular element containing tobacco and a filtering element connected to an end of said tubular element , wherein said filtering element includes at least one breakable flavouring capsule which comprises:at least one core comprising at least one lipophilic substance and at least one flavouring agent dispersed or dissolved in said lipophilic substance; andat least one breakable coating which coats said core and which comprises at least one chitosan having a weight average molecular weight (Mw) comprised between 25 kDa and 400 kDa.2. The device according to claim 1 , wherein said at least one chitosan has a weight average molecular weight (Mw) comprised between 50 kDa and 350 kDa.3. The device according to claim 1 , wherein said at least one chitosan has a Brookfield viscosity claim 1 , measured at 25° C. on an aqueous solution at 1% by weight of acetic acid containing 1% by weight of chitosan claim 1 , from 20 to 300 cP.4. The device according to claim 1 , wherein said at least one lipophilic substance is selected from the group consisting of: triglycerides claim 1 , in particular medium-chain C-Cfatty acid ...

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Номер записи: 28
15-09-2022 дата публикации

METHOD OF MANUFACTURING A TOY USING A MODEL FRAME IN LIQUID AND AN APPARATUS FOR PERFORMING A METHOD

Номер: US20220288818A1
Автор: SUNWOO Yoon
Принадлежит:

A method of manufacturing a toy using a model frame in liquid includes: filling a water tank; dissolving calcium chloride, a powder component, into the water filled in the water tank; wherein the amount of calcium chloride is determined in anticipation of the degree of gelation by chemical action with sodium alginate, filling a liquid paint to the model frame; wherein the liquid paint is comprised water 96 wt. %, CNC 0.99 wt. %, sodium alginate 3 wt. %, luminous material 0.01 wt. % or water 91 wt. %, CNC 1 wt. %, sodium alginate 3 wt. %, shiny material 5 wt. % or water 96 wt. %, CNC 0.99 wt. %, sodium alginate 3 wt. %, color conversion material 0.01 wt. %; immersing the model frame filled with the liquid paint in the water tank; solidifying and shrinking the liquid paint filled in the model frame immersed in the water tank; and shaking the model frame. 1. A method of manufacturing a toy using a model frame in liquid comprising the steps of:filling a water tank with a certain amount of water so that a model frame can be completely immersed;dissolving calcium chloride, a powder component, into the water filled in the water tank;wherein the amount of calcium chloride is determined in anticipation of the degree of gelation by chemical action with sodium alginate,filling a liquid paint to the model frame;wherein the liquid paint is comprised water 96 wt. %, CNC 0.99 wt. %, sodium alginate 3 wt. %, luminous material 0.01 wt. % or water 91 wt. %, CNC 1 wt. %, sodium alginate 3 wt. %, shiny material 5 wt. % or water 96 wt. %, CNC 0.99 wt. %, sodium alginate 3 wt. %, color conversion material 0.01 wt. %,wherein the liquid paint is added with a predetermined dye and has a predetermined viscosity;immersing the model frame filled with the liquid paint in the water tank;solidifying and shrinking the liquid paint filled in the model frame immersed in the water tank; andshaking the model frame so that the solidified and contracted toy is separated from the model frame;wherein the ...

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Номер записи: 29
25-05-2017 дата публикации

METHOD FOR PRODUCING SIMULATED ANIMAL ORGAN AND SIMULATED ANIMAL ORGAN

Номер: US20170148355A1
Автор: TAKAYAMA Seiichiro
Принадлежит:

A method for producing a simulated animal organ includes: a shaping step of mixing a raw material containing mannan as a main component and water for gelatinization and shaping a gelatinized substance into a shape of an animal organ to obtain a shaped body; and a low temperature step of keeping the shaped body in a low temperature environment lower than normal temperature. As a result, a simulated animal organ in a state extremely close to an actual animal organ is provided. 1. A method for producing a simulated animal organ comprising:a shaping step of mixing a raw material containing mannan as a main component and water for gelatinization and shaping a gelatinized substance to obtain a shaped body; anda low temperature step of keeping the shaped body in a low temperature environment lower than normal temperature.2. The method for producing a simulated animal organ according to claim 1 ,wherein the shaped body is kept at 0° C. or lower in the low temperature step.3. The method for producing a simulated animal organ according to claim 1 ,wherein the shaped body is frozen in the low temperature step.4. The method for producing a simulated animal organ according to claim 1 ,wherein an electrolyte is mixed with the water in the shaping step.5. The method for producing a simulated animal organ according to claim 4 ,wherein the electrolyte is mixed at 1.0% by weight or less.6. The method for producing a simulated animal organ according to claim 4 ,wherein the electrolyte is sodium chloride.7. The method for producing a simulated animal organ according to claim 1 ,wherein a thickener is mixed in the shaping step.8. The method for producing a simulated animal organ according to claim 1 , further comprising:a drying step of drying the shaped body.9. The method for producing a simulated animal organ according to claim 8 ,wherein the drying step is performed after the low temperature step.10. The method for producing a simulated animal organ according to claim 8 ,wherein the ...

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Номер записи: 30
31-05-2018 дата публикации

METHODS OF EXTRUDING MULTILAYER FIBERS

Номер: US20180147767A1
Автор: Grolman Joshua M.
Принадлежит:

The present disclosure is directed to tubular fibers and methods of making thereof. In some cases, the fibers may be made of a hydrogel, in some cases an alginate hydrogel. The tube may have a nonsolid inner layer and an outer layer surrounding the inner layer. At least one of the inner layer and the outer layer may contain cells. In some cases, the tubular fiber may be used to study intercellular interactions. 1. A method of making a multilayer fiber for use as a biological tissue model , the method comprising:injecting a first fluid into a first flow channel at a first flow rate;injecting a second fluid into a second flow channel at a second flow rate, the second flow channel radially surrounding the first flow channel; andinjecting a third fluid into a third flow channel at a third flow rate, the third flow channel radially surrounding the second flow channel and having an outlet downstream of the first and second flow channels; andextruding a multilayer fiber from the outlet, the multilayer fiber having an outer layer comprising a hydrogel formed by gelation of the second fluid and an inner layer comprising the first fluid.2. The method of claim 1 , wherein the first flow channel is positioned substantially concentrically within the second flow channel.3. The method of any of claim 1 , wherein the second flow channel is positioned substantially concentrically within the third flow channel.4. The method of claim 1 , wherein the second fluid is a viscoelastic material.5. The method of claim 1 , wherein the second fluid comprises alginate.6. The method of claim 1 , wherein the first fluid comprises a tissue culture medium.7. The method of claim 1 , wherein at least one of the first fluid and the third fluid comprises a first gelating agent.8. (canceled)9. (canceled)10. (canceled)11. The method of claim 1 , wherein the multilayer fiber has a folded structure claim 1 , a first portion of the outer layer of the tubular fiber being in contact with and overlying a ...

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Номер записи: 31
11-06-2015 дата публикации

METHOD FOR PREPARING A CHITOSAN-BASED POROUS LAYER

Номер: US20150158209A1
Автор: Buffin Maud, Claret Julien, François Sébastien, Ladet Sébastien
Принадлежит:

Method for preparing a chitosan-based porous layer The present invention relates to a method or preparing a chitosan-based, neutralized compressed porous layer, comprising the following steps: —a) a chitosan solution is prepared, —b) said solution is poured into a mould in order to form a layer, —c) the layer obtained in b) is lyophilized so as to obtain a porous layer, —d) said porous layer obtained in c) is compressed, —e) the compressed porous layer obtained in d) is neutralized by means of an NHOH solution. It also relates to an implant comprising a layer obtained according to such a method. 114-. (canceled)15. A method for preparing a chitosan-based porous layer which has been compressed , neutralized and washed , comprising the following steps:a) preparing a chitosan solutionb) pouring the solution into a mold in order to form a layer,c) lyophilizing the layer obtained in b) to obtain a porous layer,d) compressing the porous layer obtained in c) to obtain a compressed porous layer,{'sub': '4', 'e) neutralizing the compressed porous layer obtained in d) by using a NHOH solution to obtain a neutralized compressed porous layer, and,'}f) subjecting the neutralized compressed porous layer obtained in e) to one or more washing steps.16. The method according to claim 15 , wherein the chitosan solution prepared in step a) is a solution of chitosan in water having a chitosan concentration ranging from 0.6% to 5% by weight claim 15 , relative to a total weight of the solution.17. The method according to claim 15 , wherein the chitosan solution prepared in step a) is a solution of chitosan in water having a chitosan concentration ranging from 2% to 3% by weight claim 15 , relative to a total weight of the solution.18. The method according to claim 15 , wherein the chitosan includes a degree of acetylation ranging from 0 to 70%.19. The method according to claim 15 , wherein the chitosan includes a degree of acetylation ranging from 1% to 10%.20. The method according to ...

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Номер записи: 32
07-06-2018 дата публикации

A MEMBRANE-FORMING COMPOSITION, SOFT AND HARD CAPSULES PREPARED BASED ON THIS COMPOSITION AND THE PREPARATION METHODS

Номер: US20180154327A1
Автор: DOU Xiao, LEI Peng, LIU Peiyong, WANG LI, ZHANG Yichi, Zhu Xudong
Принадлежит: JIANGSU LEFAN CAPSULE CO., LTD.

A membrane-forming composition, soft and hard capsules prepared based on the composition and the preparation methods are described. The membrane-forming composition includes pullulan polysaccharide, gellan gum, amino acid moisturizing agent, anti-hygroscopic agent and so on. It is suitable for the fabrication of hard or soft capsules. The membrane-forming composition can gelate without alkali metal ions. It has a high moisture retention rate which makes it not easy to take up moisture and turn soft in high humid environment, and it will not turn yellow during long time storage. Furthermore, the membrane-forming composition is made up of pure natural materials. 1. A membrane-forming composition comprising pullulan polysaccharide , gellan gum and a methylglycine-proline moisturizing agent.2. The membrane-forming composition according to claim 1 , further comprising an anti-hygroscopic agent.3. The membrane-forming composition according to claim 1 , wherein the gellan gum is a high acyl gellan gum.4. The membrane-forming composition according to claim 2 , wherein the anti-hygroscopic agent has one or a combination of stearic acid and lauric acid in any proportion.5. The membrane-forming composition according to claim 1 , further comprising a plasticizer.6. The membrane-forming composition according to claim 5 , wherein the plasticizer is glycerin.7. A hard capsule containing pullulan polysaccharide claim 1 , wherein the hard capsule is prepared by the membrane-forming composition according to .8. A soft capsule containing pullulan polysaccharide claim 5 , wherein the soft capsule is prepared by the membrane-forming composition according to .9. The hard capsule containing pullulan polysaccharide according to claim 7 , wherein the membrane-forming composition consists of following components:pullulan polysaccharide 76-90 weight percent, gellan gum 0.5-4 weight percent, methylglycine-proline moisturizing agent 0.05-2 weight percent, anti-hygroscopic agent 0-1 weight ...

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Номер записи: 33
16-06-2016 дата публикации

ADDITIVE MANUFACTURING OF EMBEDDED MATERIALS

Номер: US20160167312A1
Автор: Feinberg Adam, Hinton Thomas
Принадлежит:

In one aspect, a method includes providing support material within which the structure is fabricated, depositing, into the support material, structure material to form the fabricated structure, and removing the support material to release the fabricated structure from the support material. The provided support material is stationary at an applied stress level below a threshold stress level and flows at an applied stress level at or above the threshold stress level during fabrication of the structure. The provided support material is configured to mechanically support at least a portion of the structure and to prevent deformation of the structure during the fabrication of the structure. The deposited structure material is suspended in the support material at a location where the structure material is deposited. The structure material comprises a fluid that transitions to a solid or semi-solid state after deposition of the structure material. 1. A method for fabricating a structure having at least two dimensions , the method comprising:providing support material within which the structure is fabricated;wherein the provided support material is stationary at an applied stress level below a threshold stress level and flows at an applied stress level at or above the threshold stress level during fabrication of the structure; andwherein the provided support material is configured to mechanically support at least a portion of the structure and to prevent deformation of the structure during the fabrication of the structure;depositing, into the support material, structure material to form the fabricated structure;wherein the deposited structure material is suspended in the support material at a location where the structure material is deposited; andwherein the structure material comprises a fluid that transitions to a solid or semi-solid state after deposition of the structure material; andremoving the support material to release the fabricated structure from the support ...

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Номер записи: 34
16-06-2016 дата публикации

PROCESS FOR PRODUCING PURIFIED POLYSACCHARIDE FIBERS, PURIFIED POLYSACCHARIDE FIBERS AND TIRES

Номер: US20160168757A1
Автор: KOIDE Mitsuharu, SUGIMOTO Kenichi
Принадлежит: BRIDGESTONE CORPORATION

A process for producing purified polysaccharide fiber of the present invention includes bringing a polysaccharide solution, which is obtained by dissolving a polysaccharide raw material in a liquid containing an ionic liquid, into contact with a solidification liquid containing an ionic liquid, and performing dry-wet spinning on polysaccharide, in which the concentration of the ionic liquid in the solidification liquid is 0.4% by weight to 70% by weight, and a distance D from a site where the polysaccharide solution is extruded in the form of fiber to a site where the extruded polysaccharide solution comes into contact with the solidification liquid is 50 mm to 120 mm. 1. A process for producing purified polysaccharide fiber , comprising:bringing a polysaccharide solution, which is obtained by dissolving a polysaccharide raw material in a liquid containing an ionic liquid, into contact with a solidification liquid containing an ionic liquid; andperforming dry-wet spinning on polysaccharide,wherein the concentration of the ionic liquid in the solidification liquid is 0.4% by weight to 70% by weight, anda distance D from a site where the polysaccharide solution is extruded in the form of fiber to a site where the extruded polysaccharide solution comes into contact with the solidification liquid is 50 mm to 120 mm.2. The process for producing purified polysaccharide fiber according to claim 1 ,wherein the concentration of the ionic liquid in the solidification liquid is 20% by weight to 40% by weight.5. The process for producing purified polysaccharide fiber according to claim 1 ,wherein and/or of the ionic liquid in the polysaccharide solution and the ionic liquid in the solidification liquid are 1-ethyl-3-methylimidazolium diethylphosphate.6. Purified polysaccharide fiber produced by the process for producing purified polysaccharide fiber according to .7. A tire using a fiber-rubber complex obtained by combining the purified polysaccharide fiber according to with a ...

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Номер записи: 35
23-06-2016 дата публикации

PROSTHETIC APPLIANCE KIT

Номер: US20160175621A1
Автор: Bettles Stephen
Принадлежит:

Prosthetics created in layers, and methods of making them, comprising one or more materials. The methods utilize a clay sculpture from which is made a negative impression cast in silicone, which is used to cast a durable positive prosthetic, which is used to create either durable or temporary negative production impressions into which the layers can be built to form the finished prosthetic. 1. A prosthetic appliance comprising layers of a skin safe plastic encapsulation cover , an adhesive layer , a platinum silicone layer , an adhesive layer , a skin safe plastic encapsulation cover layer , a pressure adhesive layer and a release film layer.2. The prosthetic appliance of in which the layers are as follows: the first layer is a skin safe plastic encapsulation cover claim 1 , the second layer is an adhesive claim 1 , the third layer is platinum silicone claim 1 , the fourth layer is an adhesive claim 1 , the fifth layer is a skin safe plastic encapsulation cover claim 1 , the sixth layer is a pressure adhesive and the seventh layer is release film.3. The prosthetic appliance of in which the release film is comprised of two pieces of release film claim 1 , of paper claim 1 , plastic or metallic foil claim 1 , in which one piece overlaps the other.4. The prosthetic appliance of in which the release film is coated with cross linkable silicone or a low surface energy material.5. The prosthetic appliance of in which the platinum silicone comprises a softener and a pigment to tint.6. The prosthetic appliance of in which the platinum silicone is softened using a deadener.7. A prosthetic appliance comprising six layers skin safe plastic encapsulation cover layer claim 5 , a platinum silicone layer claim 5 , an adhesive layer claim 5 , a skin safe plastic encapsulation cover layer claim 5 , a pressure adhesive layer and a release film layer.8. A prosthetic appliance comprising five layers: skin safe plastic encapsulation cover layer claim 5 , a platinum silicone layer claim 5 ...

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Номер записи: 36
23-06-2016 дата публикации

POLYSACCHARIDE FIBERS AND METHOD FOR PRODUCING SAME

Номер: US20160177471A1
Автор: Firgo Heinrich, Kraft Gregor, Kroner Gert, Röder Thomas
Принадлежит: Lenzing AG

The present invention relates to a direct dissolving process for the production of polysaccharide fibers which contain α(1→3)-glucan as a fiber-forming substance, with aqueous sodium hydroxide solution as a solvent, as well as to the fibers made thereby, and to their use. 1. A method for the production of a polysaccharide fiber whose fiber-forming substance is α(1→3)-glucan , wherein the method is a direct dissolving process which comprises the step of spinning the fiber by extruding a spinning solution comprising an aqueous sodium hydroxide solution , wherein the spinning occurs in a spin bath , and wherein a spun fiber is formed.2. The method according to claim 1 , wherein the aqueous sodium hydroxide solution concentration in the spinning solution is between 4.0 and 5.5% by weight related to the total quantity of the spinning solution.3. The method according to claim 1 , wherein the spin bath comprises HSOin a concentration between 200 and 500 g/l.4. The method according to claim 1 , wherein the HSOconcentration in the spin bath is between 20 and 60 g/l.5. The method according to claim 1 , wherein the spun fiber is subsequently stretched in an acid regeneration bath.6. The method according to claim 1 , wherein at least 90% of the α(1→3)-glucan are hexose units and at least 50% of the hexose units are linked via α(1→3)-glycosidic bonds.7. The method according to claim 1 , claim 1 , claim 1 , claim 1 , claim 1 , or claim 1 , wherein the fiber is selected from the group consisting of a staple fiber and a continuous filament.8. A polysaccharide fiber whose fiber-forming substance is α(1→3)-glucan claim 1 , wherein the fiber is produced using a direct dissolving process in aqueous sodium hydroxide solution.9. The fiber according to claim 8 , wherein at least 90% of the α(1→3)-glucan are hexose units and at least 50% of the hexose units are linked via α(1→3)-glycosidic bonds.10. The fiber according to or claim 8 , wherein the fiber is selected from the group consisting ...

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Номер записи: 37
09-07-2015 дата публикации

PRODUCTION OF POLY ALPHA-1,3-GLUCAN FILMS

Номер: US20150191550A1
Автор: Dennes T Joseph, Mishra Vindhya
Принадлежит:

The present invention is directed toward a process for making a poly alpha-1,3-glucan film. These films can be transparent or translucent and used in packaging applications. 1. A process for making a poly alpha-1 ,3-glucan film comprising:(a) dissolving poly alpha-1,3-glucan in a solvent composition to provide a solution of poly alpha-1,3-glucan;(b) contacting the solution of poly alpha-1,3-glucan with a surface; and(c) removing the solvent composition to form a poly alpha-1,3-glucan film.2. The process according to claim 1 , wherein the solvent composition is selected from the group consisting of aqueous sodium hydroxide claim 1 , aqueous potassium hydroxide claim 1 , aqueous tetraethyl ammonium hydroxide claim 1 , and a mixture of lithium chloride and dimethyl sulfoxide.3. The process according to claim 2 , wherein the solvent composition further comprises at least one of a solubility additive or a plasticizer additive.4. The process according to claim 3 , wherein the solubility additive is urea.5. The process according to claim 3 , wherein the plasticizer additive is glycerol.6. The process according to claim 1 , wherein removing the solvent composition comprises evaporation and coagulation in water claim 1 , acid or alcohol.7. A poly alpha-1 claim 1 ,3-glucan film made according to .8. A film comprising poly alpha-1 claim 1 ,3-glucan.9. The film according to claim 8 , wherein the film has at least one of:(a) haze less than about 10%;(b) breaking stress from about 10 to about 80 MPa;(c) tear strength from about 250 to about 3000 gf/mm;(d) Gurley air permeability less than about 10 s; and{'sup': '2', '(e) oxygen permeation rate less than about 0.3 cc-mm/mday at 23° C., 0% RH.'} This invention claims the benefit of priority of U.S. Provisional Application Nos. 61/923,900, filed on Jan. 6, 2014, and 61/928,571, filed on Jan. 17, 2014, the entirety of which are herein incorporated by reference.This invention relates to poly alpha-1,3-glucan films and methods of their ...

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Номер записи: 38
18-09-2014 дата публикации

Sucrose Treated Carbon Nontube and Graphene Yarns and Sheets

Номер: US20140273695A1
Автор: Emilie J. Siochi, Godfrey Sauti, Jae-Woo Kim, Kristopher E. WISE
Принадлежит: National Aeronautics and Space Administration NASA

Consolidated carbon nanotube or graphene yarns and woven sheets are consolidated through the formation of a carbon binder formed from the dehydration of sucrose. The resulting materials on a macro-scale are lightweight and of a high specific modulus and/or strength. Sucrose is relatively inexpensive and readily available, and the process is therefore cost-effective.

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Номер записи: 39
13-07-2017 дата публикации

PRODUCTION OF POLY ALPHA-1,3-GLUCAN FORMATE FOOD CASINGS

Номер: US20170196231A1
Автор: Geogre Matthew W., MASSOUDA DEBORA FLANAGAN, Mishra Vindhya
Принадлежит:

An extrusion process for making a poly alpha-1,3-glucan formate food casing is disclosed. 1. A process for making a poly alpha-1 ,3-glucan formate food casing comprising:(a) dissolving poly alpha-1,3-glucan in a solvent composition comprising formic acid to provide a solution of poly alpha-1,3-glucan formate;(b) extruding the solution of poly alpha-1,3-glucan formate into a coagulation bath to make a tube-shaped wet gel;(c) optionally, washing the tube-shaped wet gel with water; and(d) removing the water from the tube-shaped wet gel to form a poly alpha-1,3-glucan formate food casing.2. The process according to claim 1 , wherein the coagulation bath comprises water.3. The process according to claim 2 , wherein the water contains a dilute aqueous base.4. The process according to claim 1 , further comprising the solution of poly alpha-1 claim 1 ,3-glucan formate in (b) is coextruded over an extruded food product into a coagulation bath to make a tube-shaped wet gel covering an extruded food product.5. A poly alpha-1 claim 1 ,3-glucan formate food casing made according to or .6. A food casing comprising poly alpha-1 claim 1 ,3-glucan formate.7. The food casing according to claim 6 , wherein the food casing has a breaking stress from about 10 to about 100 MPa.8. A food casing comprising poly alpha-1 claim 6 ,3-glucan formate covering a food product. This disclosure claims the benefit of priority of U.S. Provisional Application No. 62/017507, filed on Jun. 26, 2014, the entirety of which is herein incorporated by reference.This invention relates to poly alpha-1,3-glucan formate food casings, methods of their preparation and poly alpha-1,3-glucan formate coated food products.Glucose-based polysaccharides and their derivatives can be of potential industrial application.Cellulose is a typical example of such a polysaccharide and is comprised of beta-1,4-D-glycosidic linkages of hexopyranose units. Cellulose is used for several commercial applications such as in manufacture ...

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Номер записи: 40
27-07-2017 дата публикации

PRODUCTION OF POLY ALPHA-1,3-GLUCAN FOOD CASINGS

Номер: US20170208823A1
Автор: George Matthew W., MASSOUDA DEBORA FLANAGAN, Mishra Vindhya
Принадлежит:

An extrusion process for making a poly alpha-1,3-glucan food casing is disclosed. 1. A process for making a poly alpha-1 ,3-glucan food casing comprising:(a) dissolving poly alpha-1,3-glucan in a solvent composition to provide a solution of poly alpha-1,3-glucan;(b) extruding the solution of poly alpha-1,3-glucan into a coagulation bath to make a tube-shaped wet gel;(c) washing the tube-shaped wet gel with water;(d) optionally, plasticizing the tube-shaped wet gel with a plasticizer additive; and(e) removing the water from the tube-shaped wet gel to form a poly alpha-1,3-glucan food casing.2. The process according to claim 1 , wherein the solvent composition is an aqueous base.3. The process according to claim 2 , wherein the aqueous base is selected from the group consisting of aqueous potassium hydroxide claim 2 , aqueous sodium hydroxide and aqueous tetraethyl ammonium hydroxide.4. The process according to claim 1 , wherein the solvent composition further comprises a solubility additive claim 1 , a plasticizer additive or a mixture thereof.5. The process according to claim 1 , wherein the coagulation bath comprises an aqueous acid or methanol.6. The process according to claim 5 , wherein the aqueous acid comprises aqueous sulfuric acid.7. The process according to claim 5 , wherein the coagulation bath further comprises sodium sulfate claim 5 , boric acid or a mixture thereof.8. The process according to claim 1 , further comprising the solution of poly alpha-1 claim 1 ,3-glucan in (b) is coextruded over an extruded food product into a coagulation bath to make a tube-shaped wet gel covering an extruded food product.9. A poly alpha-1 claim 1 ,3-glucan food casing made according to or .10. A food casing comprising poly alpha-1 claim 1 ,3-glucan.11. The food casing according to claim 10 , wherein the food casing has a breaking stress from about 10 to about 100 MPa.12. A food casing comprising poly alpha-1 claim 10 ,3-glucan covering a food product. This disclosure ...

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Номер записи: 41
04-08-2016 дата публикации

METHOD OF PRODUCING A SWELLABLE POLYMER FIBRE

Номер: US20160222548A1
Автор: AGBOH Christopher Ochayi
Принадлежит: XIROS LIMITED

A swellable polymer based fibre and a method of preparing the same optionally comprising glycol, lecithin and optionally an antimicrobial metal species suitable, for example, for medical applications including wound dressings. A method of manufacture may comprise fibre extrusion or spinning involving one or a plurality of in-series coagulation baths to add single or multiple antimicrobial metal species to the as-formed fibre. 1. A method of forming a swellable polymer based fibre comprising:creating an aqueous dope solution containing a water soluble polymer;spinning or extruding the dope solution into a coagulation bath to form an extruded fibre;drawing the fibre from the coagulation bath;characterised by:adding a glycol to the dope solution, the glycol having between two to fifteen carbon atoms.2. The method as claimed in further comprising adding a metal based antimicrobial agent to the dope solution.3. The method as claimed in wherein the antimicrobial agent comprises silver claim 2 , a silver ion or a silver substrate.4. The method as claimed in further comprising adding a metal based antimicrobial agent to the coagulation bath.5. The method as claimed in wherein the antimicrobial agent is a metal ion selected from any one or a combination of the following set of:Zn, Cu, Ti, Pt, Pd, Bi, Sn, Sb.6. (canceled)7. The method as claimed in wherein the polymer comprises any one or a combination of a polysaccharide or a hydrocolloid forming polymer and optionally pectin claim 1 , alginate claim 1 , psyllium claim 1 , carboxymethylcellulose claim 1 , konjae claim 1 , aloe vera and/or chitosan.8. (canceled)9. The method as claimed in wherein the glycol comprises between two to fifteen carbon atoms.10. (canceled)11. (canceled)12. (canceled)13. The method as claimed in wherein the glycol is added at a concentration of 0.05 to 10% by weight of the dope solution.14. The method as claimed in further comprising adding any one or a combination of the following to the dope ...

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Номер записи: 42
03-08-2017 дата публикации

Molding machine and method of molding a part

Номер: US20170217073A1
Автор: Richard Ernest Fitzpatrick
Принадлежит: Extrude To Fill Inc

The present disclosure provides a molding machine and a method of molding a part. The molding machine may include multiple molding systems (e.g., extruders) for pumping molten material into one or more mold cavities. The multiple molding systems may pump the same material or different materials into the one or more mold cavities. The multiple molding systems may be individually and/or collectively controlled. A method of molding a part may include pumping material into one or more mold cavities via multiple molding systems, ceasing pumping material into the one or more mold cavities when one or more pressures associated with the multiple molding systems are achieved, and releasing a molded part from the one or more mold cavities after the one or more pressures are achieved.

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Номер записи: 43
19-08-2021 дата публикации

Latex dipped article with a modified polyvinyl alcohol layer which resist to water, solvents and diluted solvents

Номер: US20210251319A1
Автор: Hasini Dinushika DANGALLE, Pathirannehelage Dhammika Sameera KULATHILAKA, Rendage Sachini Sandeepa CHANDRASIRI, Upul Nishantha Ratnayake
Принадлежит: DIPPED PRODUCTS PLC

A glove is provided that includes an outer layer and an inner layer. The outer layer includes a polyvinyl alcohol (PVA) composite including PVA chemically modified with nano cellulose and pre cross linked nitrile latex. The inner layer includes nitrile latex.

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Номер записи: 44
16-08-2018 дата публикации

Process for printing 3D tissue culture models

Номер: US20180230423A1
Автор: "OMAHONY Aidan Patrick", ATAPATTU Lakmali, FIFE Christopher Michael, Gooding John Justin, KAVALLARIS Maria, RIBEIRO Julio Cesar Caldeira, Utama Robert Hadinoto
Принадлежит: Inventia Life Science Pty Ltd

A process for producing a 3D tissue culture model by (a) printing a drop of bio-ink to a substrate; (b) printing a drop en.) of activator to the drop of bio-ink to form a hydrogel droplet; (c) repeating steps (a) and (b) in any order to form a hydrogel mold adapted to receive a drop containing cells; (d) printing a drop containing cells to the hydrogel mold; and (e) repeating steps (a) and (b) in any order to form a 3D tissue culture model comprising the cells encapsulated in the hydrogel mold. 1. A process for producing a 3D tissue culture model , the process comprising:(a) printing a drop of bio-ink to a substrate;(b) printing a drop of activator to the drop of bio-ink to form a hydrogel droplet;(c) repeating steps (a) and (b) in any order to form a hydrogel mold adapted to receive a drop containing cells;{'sup': '7', '(d) printing a drop containing cells having a cell concentration of 10cells/ml or greater to the hydrogel mold; and'}(e) repeating steps (a) and (b) in any order to form a 3D tissue culture model comprising the cells encapsulated in the hydrogel mold;wherein the printing is carried out using a printer having a drop-on-demand droplet dispensing system; and wherein the 3D tissue culture model has high cell viability.2. The process according to wherein step (d) comprises printing a drop of cell-ink containing cells to the hydrogel mold.3. The process according to wherein step (d) comprises printing a drop of bio-ink containing cells and printing a drop of activator to the drop of bio-ink containing cells before step (e).4. The process according to wherein the substrate is suitable for containing claim 1 , holding or growing cells.5. The process according to wherein the substrate is selected from microtitre plate of different well configurations (6 claim 4 , 24 claim 4 , 48 and 96-well) claim 4 , microtitre plate with coverslip bottom of different well configuration (6 claim 4 , 24 claim 4 , 48 and 96-well) claim 4 , fluorodish claim 4 , chamber slides ...

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Номер записи: 45
07-09-2017 дата публикации

IMPLANTS FOR CREATING CONNECTIONS TO TISSUE PARTS, IN PARTICULAR TO SKELETAL PARTS, AS WELL AS DEVICE AND METHOD FOR IMPLANTATION THEREOF

Номер: US20170252082A1
Автор: Aeschlimann Marcel, Lanci Antonino, Mayer Jorg, Torriani Laurent
Принадлежит:

A method for locating a material having thermoplastic properties in pores of bone tissue includes providing a pin having the material having thermoplastic properties and a core, wherein the material having thermoplastic properties is arranged on the circumferential surface of the core constituting an outer region of the pin. An opening is provided in the bone tissue, and the pin is positioned at least partly in the opening. The outer region of the pin is then impinged with mechanical vibration energy for a time sufficient for liquefying at least part of the material having thermoplastic properties, and, in a liquefied state, pressing it into the pores of the bone tissue surrounding the opening. The vibration energy is stopped for a time sufficient for re-solidification of the liquefied material, and then the core is removed. 1. A method for creating a positive-fit connection capable of load-bearing to a tissue part in a human or animal body , the tissue part comprising first and second surfaces , the method comprising the steps of:providing an implant comprising a support with a proximal end and a distal base plate, the support and the base plate not being liquefiable under implantation conditions, and the implant further comprising a second material, which is biocompatible, has thermoplastic properties, and is liquefiable by mechanical oscillation,providing a tissue opening reaching from the first surface to the second surface of the tissue part, the opening having a form which is adapted to a cross section of the implant,positioning the implant with the base plate facing forward from the first surface through the opening so that the base plate is positioned beyond the second surface of the tissue part and at least portions of the second material are positioned proximally of the base plate,impinging a proximal face of the second material with mechanical oscillation and simultaneously pressing it against the base plate for a time sufficient for liquefying at least a ...

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Номер записи: 46
14-09-2017 дата публикации

Highly mineral-filled adhesive bandage or patch

Номер: US20170258698A1
Автор: Camille BENETOLLO, Cyrille CABARET, Elodie Georges
Принадлежит: Silab Sa, Societe Industrielle Limousine dApplication Biologique SA SILAB

The present invention relates to an adhesive and soluble adhesive bandage or patch comprising a soluble film of natural origin with high mineral content. The soluble film comprises from 20 to 90 wt % of mineral filler and wherein the mineral filler content level is higher than the polysaccharide content level. It also relates to these bandages or patches for use in cosmetics or therapy. Also, a method of making a soluble film

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Номер записи: 47
06-08-2020 дата публикации

COSMETICS CONTAINER AND MANUFACTURING METHOD THEREOF

Номер: US20200247020A1
Автор: KUO CHEN-CHANG
Принадлежит: TOO CHARMING ENT. CO., LTD.

A cosmetic container and manufacturing method thereof may include steps of obtaining raw material, mixing granulation, and molding by injection to manufacture a cosmetic container. In the step of obtaining raw material, a plurality of fibers as main raw material of the cosmetic container are extracted from natural plants. In the step of mixing granulation, the extracted fibers are configured to mix with a plentiful vegetable gum and starch, and the mixed compound is adapted to be granulated through a granulating machine to form into a plurality of granules. Thereafter, in the step of molding by injection, the granules is sent into a processor, and the processor is configured to heat and melt the granules and to inject and fill the melted compound in a plurality of mold cavities of a forming mold. 1. A cosmetic container and manufacturing method thereof comprising steps of obtaining raw material , mixing granulation , and molding by injection to manufacture a cosmetic container;wherein in the step of obtaining raw material, a plurality of fibers as main raw material of the cosmetic container are extracted from natural plants such that the toxic gas and smoke are not generated when the cosmetic container is burned, and residues of the burned cosmetic container are adapted to be naturally discomposed when buried, thereby achieving environmental effect;wherein the step of mixing granulation is processed after the step of obtaining raw material; the extracted fibers are configured to be mixed with a designated amount of vegetable gum and starch, and the mixed compound is adapted to be granulated through a granulating machine to form into a plurality of granules; andwherein the step of molding by injection is processed after the step of mixing granulation; the granules are sent into a processor, and the processor is configured to heat and melt the granules and to inject and fill the melted compound into a plurality of mold cavities of a forming mold; after proper cooling, ...

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Номер записи: 48
01-10-2015 дата публикации

BIODEGRADABLE HYDROPHOBIC COMPOSITE MATERIALS AND PROCESS FOR THE PREPARATION THEREOF

Номер: US20150274942A1
Автор: Chaudhary Jai Prakash, Chejara Dharmesh, Eswaran Karuppanan, Ghosh Pushpito Kumar, Meena Ramavatar, Prasad Kamalesh, Siddhanta Arup Kumar
Принадлежит: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

The present invention relates to biodegradable hydrophobic composite materials and a process for the preparation of said hydrophobic biodegradable materials from the seaweed polysaccharides through grafting reaction with vinylated monomers e.g. vinyl acetate. The said composites can be used as a substitute for synthetic ropes for varied applications including seaweed cultivation in the open sea. The results of cultivation experiments showed that ropes are suitable for cultivation of seaweeds in the sea environment, and exhibit higher biomass yield as compared to synthetic ropes. The prepared composites are very flexible and can be used for making handles for carry bags and for the preparation of biodegradable designs, bowls, pots, jars, gift items, stud caps and bracelets. 1. Hydrophobic biodegradable composites comprising:[a] seaweed derived polysaccharides in the range of 30 to 80 wt %;[b] vinylated monomer in the range of 8 to 60 wt %; and[c] plasticizer in the range of 2 to 15 wt %;wherein, the moisture content of said composites is in the range of 5 to 15 wt %.2. The composites as claimed in claim 1 , wherein the seaweed derived polysaccharides are selected from the group consisting of agar claim 1 , agarose claim 1 , alginate claim 1 , and carrageenan.3. The composites as claimed in claim 1 , wherein the seaweed derived polysaccharides are either used alone or in combination.4. The composites as claimed in claim 1 , wherein the seaweed derived polysaccharide is agar and/or agarose.5. The composites as claimed in claim 1 , wherein the vinylated monomer is vinyl acetate.6. The composites as claimed in claim 1 , wherein the plasticizer is selected from the group consisting of glycerol claim 1 , ethylene glycol claim 1 , and sorbitol.7. The composites as claimed in claim 1 , wherein the plasticizer is glycerol.8. A process for the preparation of the composites as claimed in claim 1 , the process comprising:[a] dissolving 1 to 8 wt % of seaweed polysaccharides or ...

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Номер записи: 49
11-12-2014 дата публикации

NEEDLE-LIKE MATERIAL AND METHOD FOR MANUFACTURING NEEDLE-LIKE MATERIAL

Номер: US20140361459A1
Автор: KATO Hiroyuki, Taroura Yoshikazu, YAMAMOTO Takako
Принадлежит: TOPPAN PRINTING CO., LTD.

A needle-shaped structure includes a needle-shaped projection and a support substrate supporting the projection wherein the projection contains at least a chitosan and an organic acid, places a low burden on a living body and is able to keep the microscopic form after puncture into the skin. 1. A method of producing a needle-shaped structure having a support substrate and a needle-shaped projection projected from the support substrate , the method comprising:preparing a liquid material comprising a chitosan component and an acid;applying the liquid material onto an intaglio plate having a needle-shaped recess;solidifying the liquid material applied onto the intaglio plate such that a solidified article made from the liquid material is obtained;separating the solidified article from the intaglio plate; andimmersing separated solidified article in an aqueous alcohol solution.2. The method of producing a needle-shaped structure as defined in claim 1 , wherein the aqueous alcohol solution comprises at least one alcohol selected from the group consisting of ethanol claim 1 , methanol and propanol.3. The method of producing a needle-shaped structure as defined in claim 2 , wherein the aqueous alcohol solution has a concentration of 50-90 wt %.4. The method of producing a needle-shaped structure as defined in claim 1 , wherein the immersing comprises immersing the separated solidified article in a first aqueous alcohol solution of a higher concentration and then in a second aqueous alcohol solution of a lower concentration.5. The method of producing a needle-shaped structure as defined in claim 1 , wherein the chitosan component comprises at least one material selected from the group consisting of chitosan claim 1 , chitin-chitosan claim 1 , a chitin-chitosan derivative claim 1 , glucosamine and a glucosamine derivative.6. The method of producing a needle-shaped structure as defined in claim 1 , wherein the acid comprises at least one selected from the group consisting of ...

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Номер записи: 50
29-08-2019 дата публикации

TOPICAL DRESSING COMPOSITION FOR THE TREATMENT OF DAMAGED SKIN TISSUE

Номер: US20190262494A1
Автор: KHORAKIWALA Habil F, KHORAKIWALA Zahabiya, Sharma Vijay
Принадлежит:

The present invention relates to a topical dressing composition for the treatment of damaged skin tissue in a subject, wherein said topical dressing comprises mesenchymal stem cells embedded in a topical matrix. Particularly the invention relates to a storage-stable topical dressing composition for the treatment of damaged skin tissue in a subject, wherein said topical dressing comprises up to about 40,000 mesenchymal stem cells per square centimetre embedded in a topical matrix and, optionally a pharmaceutically acceptable excipient. 1. A storage-stable topical dressing composition in the form of a bandage or patch for the treatment of damaged skin tissue in a subject , wherein said bandage or patch has thickness in the range of about 0.5 mm to about 10 mm , and comprises about 10 ,000 to about 40 ,000 mesenchymal stem cells per square centimetre embedded in a topical alginate matrix and optionally , a pharmaceutically acceptable excipient , wherein at least about 80% of the contained mesenchymal stem cells remain viable when the composition is stored at about 25° C. for a period of at least 6 months.2. The composition of claim 1 , wherein the damaged skin tissue includes traumatic wound claim 1 , surgical wound claim 1 , diabetic ulcer claim 1 , pressure ulcer claim 1 , venous ulcer claim 1 , a scar claim 1 , burn claim 1 , a skin lesion claim 1 , eczema claim 1 , and a skin ulcer.3. The composition of claim 1 , wherein at least about 85% of the contained mesenchymal stem cells remain viable when the composition is stored at about 25° C. for a period of at least about 12 months.4. The composition of claim 1 , wherein the topical dressing comprises about 10 claim 1 ,000 to about 35 claim 1 ,000 mesenchymal stem cells per square centimetre.5. The composition of claim 1 , wherein the topical dressing comprises about 10 claim 1 ,000 to about 30 claim 1 ,000 mesenchymal stem cells per square centimetre.6. The composition of claim 1 , wherein the topical alginate matrix ...

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Номер записи: 51
06-10-2016 дата публикации

METHOD OF MANUFACTURING CLEANING IMPLEMENT

Номер: US20160287029A1
Автор: KIM Jung Hoa
Принадлежит:

This invention relates to a method of manufacturing a cleaning implement, including placing a natural loofah in a portion of a mold having an inner space, producing a mixed solution, which is then added with a konjac powder and stirred, thus preparing a feed mixture, placing the feed mixture in a portion of the mold other than the portion containing the natural loofah so as to be shaped such that the natural loofah and the feed mixture adhere to each other, and performing aging, steam heating and cooling. 1. A method of manufacturing a cleaning implement , comprising:placing a natural loofah in a portion of a mold having an inner space;mixing water, a neutralizing agent, a mordanting agent, a foaming agent, an emulsifier and glycerin to obtain a mixed solution, which is then added with a konjac powder and stirred, thus preparing a feed mixture;placing the feed mixture in a portion of the mold other than the portion containing the natural loofah so as to be shaped such that the natural loofah and the feed mixture adhere to each other;aging the feed mixture in the mold at 20˜30° C. for 5-20 hr;steam heating the feed mixture at 90˜110° C. for 1˜5 hr using a steam heater, thus forming a natural loofah-adhered sponge;cooling the natural loofah-adhered sponge to 20˜25° C. for 1˜2 hr;quenching the natural loofah-adhered sponge to −35˜−25° C. for 2˜4 hr in a freezer;primarily freezing the natural loofah-adhered sponge to −15˜−10° C. for 3˜4 days in a freezer;primarily thawing the natural loofah-adhered sponge at 20˜30° C., thus removing the water, the neutralizing agent, the mordanting agent, the foaming agent, the emulsifier and the glycerin from the sponge by leakage;secondarily freezing the natural loofah-adhered sponge to −15˜−10° C. for 3˜4 days;secondarily thawing the natural loofah-adhered sponge at 20˜30° C., thus removing the water, the neutralizing agent, the mordanting agent, the foaming agent, the emulsifier and the glycerin remaining in the sponge by leakage; ...

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Номер записи: 52
05-10-2017 дата публикации

Polysaccharide film and method for the production thereof

Номер: US20170283568A1
Автор: Andreas Schweigart, Elisabeth REITER, Franz DÜRNBERGER, Gerold Riedl, Gert Kroner
Принадлежит: Lenzing AG

The present invention relates to a method for the production of films made of polysaccharides which, as a fiber-forming substance, contain α(1→3)-glucan, as well as to the films made thereof and to their use.

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Номер записи: 53
27-08-2020 дата публикации

Resin Composition and Molding Method Thereof

Номер: US20200270430A1
Автор: Kusumawardhani Laksmi, Morita Seiji, Nasukawa Jin, Sato Kenichi
Принадлежит:

A resin composition for molding having excellent heat resistance, hardness, cost-effectiveness and biodegradability is provided by using amorphous resin material components extracted from plant-derived wood. The resin composition includes a first resin including a hemicellulose or a hemicellulose derivative and a second resin including polymethylmethacrylate (PMMA, acrylic), polycarbonate (PC), cyclo olefin polymer (COP), cyclo olefin copolymer (COC), polypropylene (PP), polyethylene (PE), polyethylene terephthalate (PET), or polystyrene (PS) and has excellent injection moldability. 3. The resin composition for molding of claim 1 , further comprising a second resin including one of polycarbonate (PC) claim 1 , cyclo olefin polymer (COP) claim 1 , cyclo olefin copolymer (COC) claim 1 , polypropylene (PP) claim 1 , polyethylene (PE) claim 1 , polyethylene terephthalate (PET) claim 1 , polystyrene (PS) claim 1 , polylactic acid (PLA) claim 1 , ABS resin (ABS) claim 1 , vinyl chloride (PVC) claim 1 , vinylidene chloride (PVDC) claim 1 , vinyl acetate (PVAC) claim 1 , polymethylpentene (PMP) claim 1 , polybutene (PB) claim 1 , hydroxybenzoic acid (HBP) claim 1 , polyetherimide (PEI) claim 1 , polyacetal (POM) claim 1 , polyphenylene ether (PPE) claim 1 , polyphenylene oxide (PPO) claim 1 , polyphenylene sulfide (PPS) claim 1 , polyurethane (PUR) claim 1 , ionomer resin (10) claim 1 , fluorocarbon resin (FR) claim 1 , tetrafluoroethylene (PTFE) claim 1 , polycyclohexylenedimethylene terephthalate (PCT) claim 1 , polyethylene naphthalate (PEN) claim 1 , polyarylate (PAR) claim 1 , polyacrylonitrile (PAN) claim 1 , polyallylsulfone (PASF) claim 1 , polyamide (PA) claim 1 , polyvinyl alcohol (PVA) claim 1 , polymethacrylstyrene (MS) claim 1 , butadiene resin (BDR) claim 1 , polybutylene terephthalate (PBT) claim 1 , polyester carbonate (PPC) claim 1 , polybutylene succinate (PBS) claim 1 , norbornene resin (NB) claim 1 , polyamide (nylon) (PA) claim 1 , Teflon® claim 1 , FRP ...

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Номер записи: 54
10-09-2020 дата публикации

Method of manufacturing cell spheroid using bioink

Номер: US20200283736A1
Автор: Hyun Wook Kang, Jun Ho HEO, Seug Gyu JEON
Принадлежит: UNIST Academy Industry Research Corp

Disclosed is a process of manufacturing cell spheroids using a bioink. More particularly, provided is a method of manufacturing a cell spheroid, the method including extruding a first bioink including an alginate; extruding a second bioink including cells into the extruded first bioink; adding a calcium chloride (CaCl2) solution to the alginate included in the first bioink; and dissolving the second bioink, present in the first bioink, in a cell culture medium to form a cell spheroid from the cells.

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Номер записи: 55
26-09-2019 дата публикации

ADDITIVE MANUFACTURING OF EMBEDDED MATERIALS

Номер: US20190291350A1
Автор: Feinberg Adam, Hinton Thomas
Принадлежит:

In one aspect, a method includes providing support material within which the structure is fabricated, depositing, into the support material, structure material to form the fabricated structure, and removing the support material to release the fabricated structure from the support material. The provided support material is stationary at an applied stress level below a threshold stress level and flows at an applied stress level at or above the threshold stress level during fabrication of the structure. The provided support material is configured to mechanically support at least a portion of the structure and to prevent deformation of the structure during the fabrication of the structure. The deposited structure material is suspended in the support material at a location where the structure material is deposited. The structure material comprises a fluid that transitions to a solid or semi-solid state after deposition of the structure material. 127-. (canceled)28. A method for fabricating a structure , the method comprising:providing a support material within which the structure is fabricated;depositing, into the support material, a structure material, the depositing comprising:mechanically supporting at least a portion of the structure material by the support material during the depositing to prevent deformation of the structure material during deposition; andsuspending structure material in the support material at a location where the structure material is deposited;transitioning the structure material from a fluid to a solid or semi-solid state at the location wherein the structure material is deposited to form the structure; andremoving the support material to release the structure from the support material.29. The method of claim 28 , wherein the structure material comprises a tissue scaffold for supporting a plurality of cells claim 28 , the method further comprising incubating the structure material to form a tissue from the plurality of cells supported by the ...

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Номер записи: 56
26-10-2017 дата публикации

Natural Polymer-Based Porous Orthopedic Fixation Screw for Bone Repair and Regeneration

Номер: US20170303980A1
Автор: KUMBAR Sangamesh G., Laurencin Cato T.
Принадлежит:

A bone fixation device made of polysaccharide particles or microspheres fused into a solid structure is provided herein. The bone fixation device may be in the form of an orthopedic screw, orthopedic pin, or orthopedic plate. Methods of making the bone fixation devices described herein are provided as are methods of treating patients in need of bone repair or replacement by implanting a bone fixation device described herein in the patient at a site of bone damage, ligament damage, or bone deformity. 1. A bone fixation device comprising: a cellulose acetate-hydroxyl apatite composite , wherein the composite comprises 15% hydroxyl apatite and wherein the cellulose acetate has a molecular weight of 30 ,000 Da or 50 ,000 Da , wherein the composite is comprised of fused microspheres having a diameter of between 50 um and 400 um.2. The bone fixation device of claim 1 , wherein the composite comprises a porosity of between 33% and 37%.3. The bone fixation device of claim 1 , wherein the composite comprises pore diameters of between 120 urn and 150 um.4. The bone fixation device of claim 1 , wherein the bone fixation device is a cylindrical screw or an interference screw.5. The bone fixation device of claim 1 , wherein the cellulose acetate has a molecular weight of 50 claim 1 ,000 Da.6. A method of making a bone fixation device comprising providing a plurality of polysaccharide microspheres or polysaccharide particles in a mold claim 1 , wherein the mold is in the form of the bone fixation device; providing a solvent system having an organic solvent fraction and an aqueous fraction dropwise in the mold; removing excess solvent from the mold; and drying the microspheres or particles in the mold.7. A method of treating a patient in need of bone repair claim 1 , comprising implanting a bone fixation device in the patient at a site of bone damage claim 1 , ligament damage claim 1 , or bone deformity claim 1 , wherein the device consists of a cellulose acetate-hydroxyl apatite ...

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Номер записи: 57
26-10-2017 дата публикации

OSTEOIMPLANT COMPRISING AN INSOLUBLE FIBROUS POLYMER

Номер: US20170304502A1
Автор: Billy Didier, Gillissen Mirian, Scifert Jeffrey L., Vickers Scott M.
Принадлежит:

Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided. 1. A method for making an osteoimplant , the method comprising: applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant.2. A method of claim 1 , wherein the mechanical force is provided by a grinder or blender.3. A method of claim 1 , further comprising crosslinking the insoluble collagen fibers of the semi-solid mass prior to lyophilization.4. A method of claim 1 , wherein the slurry further comprises ceramic granules having biphasic calcium phosphate comprising tricalcium phosphate and hydroxyapatite in a ratio from about 40:60 to about 95:5.5. A method of claim 4 , wherein the ceramic granules have an average particle diameter in the range from about 0.5 to about 1.6 mm.6. A method of claim 5 , wherein the amount of biphasic calcium phosphate is in a range from about 1% to about 85% by weight based on the total weight of the osteoimplant.7. A method of claim 1 , wherein the slurry further comprises a polysaccharide claim 1 , the polysaccharide comprising starch or alginate in an amount from about 0.1% to about 12.5% by weight based on the total weight of the osteoimplant.8. A method of claim 1 , wherein the slurry further comprises a hydration agent claim 1 , the hydration agent comprising polyethyleneglycol in an amount from about 0.01% to about 1.5% by weight based on the total weight of the ...

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Номер записи: 58
17-09-2020 дата публикации

Osteoimplant comprising an insoluble fibrous polymer

Номер: US20200289711A1
Автор: Didier Billy, Jeffrey L. Scifert, Mirian Gillissen, Scott M. Vickers
Принадлежит: WARSAW ORTHOPEDIC INC

Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.

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Номер записи: 59
26-10-2017 дата публикации

TISSUE-MIMICKING HYDROGEL COMPOSITIONS FOR BIOFABRICATION

Номер: US20170307598A1
Автор: Skardal Aleksander, Soker Shay
Принадлежит:

An extrudable hydrogel composition useful for making a three-dimensional organ construct includes a cross-linkable prepolymer, a post-deposition crosslinking group, optionally, an initiator that catalyzes the reaction between the prepolymer and said the crosslinking group; live cells (e.g., plant, animal, or microbial cells), optionally at least one one growth factor, and optionally water to balance. Methods of using the same and products so made are also described. 1. An extrudable hydrogel composition useful for making a three-dimensional organ construct , comprising:(a) a cross-linkable prepolymer;(b) a post-deposition crosslinking group;(c) optionally, but in some embodiments preferably, an initiator that catalyzes the reaction between said prepolymer and said post-deposition crosslinking group;(d) live cells (e.g., plant, animal, or microbial cells); and(e) optionally, but in some embodiments preferably, at least one growth factor; and(f) optionally, water to balance.2. The composition of claim 1 , wherein said at least one growth factor comprises a decellularized extracellular matrix composition.3. The composition of claim 1 , wherein said initiator is present and comprises a thermal initiator or photoinitiator.4. The composition of claims 1 , wherein said post-deposition crosslinking group comprises a multi-arm thiol-reactive crosslinking agent.5. The composition of claims 1 , wherein said prepolymer is formed from the at least partial crosslinking reaction of: (i) an oligosaccharide and (ii) a first crosslinking agent.6. The composition of claims 1 , wherein said composition is viscous.7. The composition of claims 1 , wherein said cells are animal tissue cells.8. The composition of claims 1 , wherein said cells are encapsulated in spheroids.9. A method of making a three-dimensional organ construct claims 1 , comprising the steps of: (i) a cross-linkable prepolymer', '(ii) a post-deposition crosslinking group;', '(iii) optionally, an initiator that catalyzes ...

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Номер записи: 60
25-10-2018 дата публикации

SYSTEMS, APPARATUS AND METHODS FOR CRYOGENIC 3D PRINTING

Номер: US20180304537A1
Автор: "Shaked Zeev", Adamkievicz Michal, Rubinsky Boris
Принадлежит: The Regents of the University of California

Systems, apparatus and methods for producing objects with cryogenic 3D printing with controllable micro and macrostructure with potential applications in tissue engineering, drug delivery, and the food industry. The technology can produce complex structures with controlled morphology when the printed 3D object is immersed in a liquid coolant, whose upper surface is maintained at the same level as the highest deposited layer of the object. This ensures that the computer-controlled process of freezing is controlled precisely and already printed frozen layers remain at a constant temperature. The technology controls the temperature, flow rate and volume of the printed fluid emitted by the dispenser that has X-Y positional translation and conditions at the interface between the dispenser and coolant surface. The technology can also control the temperature of the pool of liquid coolant and the vertical position of the printing surface and pool of coolant liquid.

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Номер записи: 61
01-11-2018 дата публикации

COMPOSITION FOR THE PREPARATION OF A NANOSTRUCTURED BIODEGRADABLE POLYMERIC MATERIAL, THE MATERIAL OBTAINED AND ITS APPLICATIONS

Номер: US20180312687A1
Автор: Aucejo Romero Susana, GALET DOMINGO Ana, Gallur Blanca Miriam, Hortal Ramos Mercedes, Jordá Beneyto María, ORTUÑO MANSILLA Natalia
Принадлежит:

The composition comprises a mixture of: i) poly(L-, D-lactide) homopolymer and, optionally, poly(ε-caprolactone) homopolymer, and ii) poly(L-lactide) and poly(ε-caprolactone) diblock copolymer, where said copolymer has a molar mass of the L-lactide block of 20,000 g/mol to 200,000 g/mol and a molar mass of the ε-caprolactone block of 10,000 g/mol to 100,000 g/mol, with the molar ratio between the L-lactide block and the ε-caprolactone block of 2:1. The invention also refers to the nanostructured material obtained from this composition that is characterised by a nanostructure of two mutually self-assembled phases, one phase being formed by a polymeric matrix of poly(L-, D-lactide) units and the other phase by poly(ε-caprolactone) units self-assembled with the matrix and also its use for the manufacture of a plastic article in the form of a transparent film or thin sheet. 115.-. (canceled)16. Biodegradable composition for the preparation of a nanostructured biodegradable polymeric material , characterized in that the composition comprises a binary mixture of:i) poly(L-, D-lactide) homopolymer (PLA), andii) poly(L-lactide -b-ε-caprolactone) diblock copolymer (CPB), it has a molar mass of the L-lactide block of between 20,000 g/mol and 200,000 g/mol and a molar mass of the ε-caprolactone block of between 10,000 g/mol and 100,000 g/mol,', 'it has a molar ratio between the L-lactide block and the ε-caprolactone block of 2:1,, 'wherein the diblock copolymer (CPB) satisfies all the following conditionswherein the biodegradable composition is made to reduce oxygen and water vapor permeability.17. Biodegradable composition of claim 16 , wherein the ε-caprolactone block of the diblock copolymer (CPB) is in a concentration of between 10% and 90% claim 16 , preferably between 20% and 80% claim 16 , and still more preferably between 20% and 40% of the weight of the poly(L- claim 16 , D-lactide) homopolymer (PLA).18. Biodegradable composition of claim 17 , wherein the ε- ...

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Номер записи: 62
01-10-2020 дата публикации

METHODS AND APPARATUS FOR PREPARATION OF A VULVA REPLICA

Номер: US20200307033A1
Автор: Claus David Walter
Принадлежит: Empire Laboratories, Inc.

Embodiments of the disclosed technology generally include systems and methods for the replication of a vulva. This disclosed method and system provides an option for the creation of an adult pleasure device by replication of the consumer's vulva for use by his, her, or their partner for sexual pleasure in the absence of his, her, or their partner. However, the potential applications of this invention are not limited to such use, and have many uses, such as for a keepsake, an intimate gift, or a fun experience. 1. A method for forming a replica of a vulva comprising:preparing a body-safe molding composition comprising a solvent and a body-safe molding formula;holding the body-safe molding composition against a vulva for a period of time;removing a mold formed from the body-safe molding composition from the vulva;placing the mold into a base container;connecting the base container to a hollow container with a ridge;placing a casting formula into the hollow container, filling the base container and partially filling the hollow container at least the ridge of the hollow container;allowing the casting formula to cure, forming a cast of the vulva; andremoving the cast.2. The method of claim 1 , wherein the body-safe molding composition comprises a powder.3. The method of claim 2 , wherein the powder comprises alginate.4. The method of claim 1 , wherein preparation of the body-safe molding composition comprises thoroughly mixing the solvent and the body-safe molding formula.5. The method of claim 1 , further comprising placing an insert into the center of the mold.6. The method of claim 5 , wherein the insert comprises at least a circular shaped object.7. The method of claim 1 , wherein the casting formula has a weight of approximately 5 ounces.8. The method of claim 1 , further comprising placing the cast on a masturbation container.9. The method of claim 8 , further comprising placing a stabilizing cuff on the cast and the masturbation container.10. The method of claim 8 ...

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Номер записи: 63
01-10-2020 дата публикации

New use of isosorbide

Номер: US20200307109A1
Автор: Daniela Menozzi, Ettore Fazio, Fabio Campanini, Paola Gherardi
Принадлежит: Elantas Europe SRL

The present invention relates to the use of a composition comprising isosorbide diglycidyl ether and a curing agent as a sacrificial support, to a sacrificial support comprising isosorbide repeating units, to methods for producing the sacrificial support of the invention and to uses of the sacrificial support of the invention for producing three-dimensional objects.

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Номер записи: 64
08-11-2018 дата публикации

POLYSACCHARIDE FIBERS AND METHOD FOR PRODUCING SAME

Номер: US20180320291A1
Автор: Firgo Heinrich, Kraft Gregor, Kroner Gert, Röder Thomas
Принадлежит:

The present invention relates to a direct dissolving process for the production of polysaccharide fibers which contain α(1→3)-glucan as a fiber-forming substance, with aqueous sodium hydroxide solution as a solvent, as well as to the fibers made thereby, and to their use. 17.-. (canceled)8. A polysaccharide fiber whose fiber-forming substance is α(1→3)-glucan , wherein said fiber is produced using a direct dissolving process in aqueous sodium hydroxide solution.9. The fiber according to claim 8 , wherein at least 90% of the α(1→3)-glucan are hexose units and at least 50% of the hexose units are linked via all->3)-glycosidic bonds.10. The fiber according to or claim 8 , wherein the fiber is a staple fiber or a continuous filament.11. A textile product comprising the fiber according to .12. A non-woven product comprising the fiber according to .13. The product according to claim 8 , or claim 8 , wherein the fiber comprises a staple fiber or a continuous filament.14. The textile product according to claim 8 , wherein said product is selected from the group consisting of yarns claim 8 , woven fabrics and knitted fabrics. The present invention relates to a direct dissolving process for the production of polysaccharide fibers which contain α(1→3)-glucan as a fiber-forming substance, with aqueous sodium hydroxide solution as a solvent, as well as to the fibers made thereby, and to their use.Polysaccharides are becoming increasingly important, as they are materials that can be obtained from renewable raw materials. One of the most frequently occurring polysaccharides is cellulose. Cotton fibers, which consist almost exclusively of cellulose, are an example of the significance of polysaccharides. However, also materials obtained from other cellulosic raw materials, e.g., cellulosic synthetic fibers, are continuing to gain in importance.The generic names “viscose fibers” and “modal fibers” were assigned by BISFA (the International Bureau for the Standardization of Man-made ...

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Номер записи: 65
23-11-2017 дата публикации

ULTRASOUND PHANTOM FOR FOCUSED ULTRASOUND, METHOD FOR MANUFACTURING THE SAME, BIOMIMETIC HYDROGEL PHANTOM, METHOD FOR MANUFACTURING THE SAME, DISCOLORING METHOD AND DRUG DELIVERING METHOD USING THE SAME

Номер: US20170333007A1
Автор: Kim Se Hwa, KIM Yong Tae, Ma Dong Hee
Принадлежит: Korea Research Institute of Standards and Science

The present disclosure relates to an ultrasound phantom for a focused ultrasound wave. More specifically, the present invention provides an ultrasound phantom which mimics a body so as to correspond to a speed of sound in the body, in which agarose, sucrose, polydiacetylene vesicle, and distilled water are mixed, and a specific part onto which an ultrasound wave is irradiated by a focused ultrasound transducer is gradually discolored in accordance with a temperature. 1. An ultrasound phantom for a focused ultrasound wave , which mimics a body so as to correspond to a speed of sound in the body ,wherein agarose, sucrose, a temperature sensitive material, and distilled water are mixed, a heated specific part onto which an ultrasound wave is irradiated by a focused ultrasound transducer is gradually discolored in accordance with a temperature.2. The ultrasound phantom according to claim 1 , wherein 3 to 12 wt % of the agarose and 10 to 50 wt % of the sucrose are included.3. The ultrasound phantom according to claim 1 , wherein the temperature sensitive material is polydiacetylene vesicle.4. The ultrasound phantom according to claim 3 , wherein the polydiacetylene vesicle is mixed at a concentration of more than 0 and 100 μM or less.6. A method for manufacturing an ultrasound phantom for a focused ultrasound wave claim 3 , which mimics a body so as to correspond to a speed of sound in the body claim 3 , the method comprising:a first step of melting agarose and sucrose in distilled water;a second step of putting and mixing a mixture in a heated mixing tank;a third step of mixing polydiacetylene vesicle;a fourth step of putting the mixture manufactured in the third step in a heated mold to be cooled and solidified; anda fifth step of removing the mold to separate an ultrasound phantom.8. The method according to claim 5 , wherein in the first step claim 5 , 3 to 12 wt % of the agarose and 10 to 50 wt % of the sucrose are mixed and in the third step claim 5 , the ...

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Номер записи: 66
10-12-2015 дата публикации

MICRONEEDLE, MOULD FOR PRODUCING SAME, AND PRODUCTION METHOD FOR SAME

Номер: US20150352345A1
Автор: Han Manhee, Sul Boojoon
Принадлежит:

The present invention relates to a microneedle, to a mould for producing same, and to a production method for same. More specifically, the present invention concerns a microneedle for causing a skin-beautifying substance or drug to be absorbed via the skin, to a plastic mould for producing same, and to a production method for same. 1. A micro-needle for percutaneous delivery of a dermal cosmetic material or a drug.2. The micro-needle of claim 1 , wherein the micro-needle is made of a biocompatible material selected from the group consisting of a polysaccharide claim 1 , a polyvinyl alcohol claim 1 , a carboxyvinyl polymer claim 1 , chitosan claim 1 , hyaluronic acid claim 1 , a cellulose polymer claim 1 , and NaCl salt.3. The micro-needle of claim 1 , wherein the micro-needle has a depressed portion on at least one face thereof claim 1 , the depressed portion being as long as or longer than half of the height of the micro-needle.4. The micro-needle of claim 1 , wherein the micro-needle is of tetrahedral or pyramidal shape.5. The micro-needle of claim 4 , wherein the micro-needle has a side length or height of 50 μm to 500 μm.6. The micro-needle of claim 1 , wherein the micro-needle is dissolved in body fluid or water.7. The micro-needle of claim 1 , containing a dermal cosmetic material or a drug therein.8. The micro-needle of claim 7 , wherein the dermal cosmetic material is selected from the group consisting of an antioxidant claim 7 , a growth factor claim 7 , an anti-wrinkle agent claim 7 , and a cell culture claim 7 , or culture medium.9. The micro-needle of claim 8 , wherein the antioxidant is vitamin C or vitamin E.10. The micro-needle of claim 8 , wherein the growth factor is epithelial cell growth factor (EGF) or fibroblast growth factor (FGF).11. The micro-needle of claim 8 , wherein the cell culture or culture medium is a stem cell culture or culture medium.12. The micro-needle of claim 7 , wherein the drug is selected from the group consisting of a ...

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Номер записи: 67
07-11-2019 дата публикации

Method for manufacturing molded slime compounds

Номер: US20190337241A1
Автор: Alexie ARENA, Allison CARGILL, Emmanuel R. VALDEZ, JR., Wendy Mastal
Принадлежит: Horizon Group USA Inc

Embodiments disclosed herein provide for an improved method of manufacturing molded slime compounds. Embodiments provide for a mold device including a mold bottom and a handle, wherein the mold bottom forms a shape of the molded slime compound. Embodiments further provide for forming the molded slime compound based on an interaction between a base solution including an algin-based compound and an activator solution including a calcium-based compound.

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Номер записи: 68
31-12-2015 дата публикации

Chitosan Foam Medical Devices and Methods

Номер: US20150374877A1
Автор: Gregory Kenton W., Guo Jian Xin
Принадлежит:

The invention provides a solid foam wound dressing useful for hemorrhage control and wound repair, as well as methods for making such a wound dressing. 1. A method of making a solid foam wound dressing , comprising:I. introducing gas bubbles into the aqueous solution to form an aqueous foam, wherein the aqueous solution comprises chitosan, at least one protic acid and at least one surface active agent;II. freezing the aqueous foam; andIII. dehydrating the aqueous foam to form a solid foam.2. The method of claim 1 , wherein said dehydrating the aqueous foam comprises freeze drying the aqueous foam.3. The method of claim 1 , further comprising freezing the foam in a reduced pressure environment to expand the gas bubbles in the aqueous foam.4. The method of claim 3 , wherein the reduced pressure environment is in the range of 100 mTorr to 750 mTorr.5. The method of claim 1 , further comprising compressing the solid foam.6. The method of claim 5 , wherein the compressed solid foam is imprinted with pattern or texture to provide a microporous surface.7. The method of claim 6 , wherein soft substrates having a pattern or texture are used to imprint the solid foam.8. The method of claim 1 , wherein the protic acid is a hydrogen donator acid.9. The method of claim 8 , wherein the hydrogen donator acid is selected from the group consisting of formic acid claim 8 , acetic acid claim 8 , propionic acid claim 8 , lactic acid claim 8 , succinic acid claim 8 , glutamic acid claim 8 , tartaric acid claim 8 , citric acid claim 8 , hydrochloric acid claim 8 , nitric acid claim 8 , phosphoric acid.10. The method of claim 1 , wherein the surface-active agent is anionic claim 1 , cationic claim 1 , non-ionic claim 1 , or amphoteric.11. The method of claim 10 , wherein the cationic surface-active agent is selected from the group consisting of fatty amine halides claim 10 , cetyl trimethylammonium halides claim 10 , cetylpyrindium halides claim 10 , benzalkonium halides claim 10 , ...

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Номер записи: 69
27-12-2018 дата публикации

POLYSACCHARIDE FILM AND METHOD FOR THE PRODUCTION THEREOF

Номер: US20180371193A1
Автор: Dürnberger Franz, Kroner Gert, Reiter Elisabeth, Riedl Gerold, Schweigart Andreas
Принадлежит:

The present invention relates to a method for the production of films made of polysaccharides which, as a fiber-forming substance, contain α(1→3)-glucan, as well as to the films made thereof and to their use. 1. A method for the production of a polysaccharide film , wherein the finished spinning solution for the extrusion comprises an amine oxide , at least 23% by weight of water , related to the total quantity of the spinning solution , and , as a polysaccharide , α(1→3)-glucan.2. The method according to claim 1 , wherein the amine oxide is N-methylmorpholine-N-oxide.3. The method according to claim 1 , wherein at least 90% of the α(1→3)-glucan consist of hexose units and at least 50% of the hexose units are linked via α(1→3)-glycosidic bonds.4. The method according to claim 1 , wherein the extrusion is carried out by means of a straight slot die or an annular slot die.5. The method according to in claim 1 , wherein the spinning solution is stretched following the extrusion.6. A polysaccharide film comprising a film-forming substance claim 1 , wherein the film-forming substance consists substantially of α(1→3)-glucan.7. (canceled)8. (canceled) The present invention relates to a method for the production of films made of polysaccharides which, as a fiber-forming substance, contain □(1□3)-glucan, as well as to the films made thereof and to their use. For the purposes of the present invention, the terms “film” and “sheet” shall be used as being synonymous.Polysaccharides are becoming increasingly important, as they are materials that can be obtained from renewable raw materials. One of the most frequently occurring polysaccharides is cellulose. Cotton fibers, which consist almost exclusively of cellulose, are an example of the significance of polysaccharides. However, also materials obtained from other cellulosic raw materials, e.g., cellulosic synthetic fibers, are continuing to gain in importance. In addition to the fibers, there also exist other cellulosic shaped ...

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Номер записи: 70
24-06-1997 дата публикации

Highly insulative cementitious matrices and methods for their manufacture

Номер: US5641584A
Автор: Per Just Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Insulation barriers incorporating a cementitious structural matrix formed from a cementitious mixture including a hydraulic cement and water. The insulation barriers are manufactured from cementitious materials in order to be lightweight, insulative, less expensive, and more environmentally compatible than those currently used; they may augment, and even take the place of, traditional insulation materials including insulations made of glass fibers, polyurethane foam, urea-formaldehyde foam, polystyrene, wood fiber, cellulose fiber, rock-wool, etc. The cementitious structural matrix of the insulation barriers usually includes a hydraulic cement paste (formed from the reaction of water with, e.g., a portland-type cement) in combination with a rheology-modifying agent, such as methylhydroxyethylcellulose, and a lightweight aggregate material, which lowers the density of the insulation barrier and increases its insulation ability. Fibrous materials may be incorporated into the cementitious mixture to increase the strength of the final product, while a discontinuous phase of nonagglomerated voids may be incorporated into the cementitious structural matrix to decrease the density and increase the insulation ability of the final product.

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Номер записи: 71
27-08-1996 дата публикации

Methods for the extrusion of novel, highly plastic and moldable hydraulically settable compositions

Номер: US5549859A
Автор: Per J. Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Hydraulically settable mixtures and methods for extruding such mixtures into a variety of objects which are form-stable in the green state. High green strength is achieved by increasing the yield stress of the mixture while maintaining adequate extrudability. Optimizing the particle packing density while including a deficiency of water yields a hydraulically settable mixture which will flow under pressures typically associated with the extrusion of clay or plastic. In addition, a rheology-modifying agent can be added to increase the yield stress of the mixture while not significantly increasing the viscosity. The desired strength properties and other performance criteria of the final hardened extruded product are controlled by adding aggregates, fibers, a hydraulically settable binder, water, and other admixtures.

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Номер записи: 72
03-12-1996 дата публикации

Methods for manufacturing articles of manufacture from hydraulically settable sheets

Номер: US5580409A
Автор: Per J. Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions and methods for manufacturing containers from sheets having a hydraulically settable matrix. Suitable compositions are prepared by mixing together a hydraulic binder, water, and appropriate additives (such as aggregates, fibers, and rheology-modifying agents) which impart predetermined properties so that a sheet formed therefrom has the desired performance criteria. Hydraulically settable sheets are formed from the mixture by extrusion, then calendering the sheets using a set of rollers and then drying the sheets in an accelerated manner to substantially harden the sheets. The resulting hydraulically settable sheets may have properties substantially similar to sheets made from presently used materials like paper, cardboard, polystyrene, or plastic. The sheets can be laminated, corrugated, coated, printed on, scored, perforated, cut, folded, rolled, spiral wound, molded, assembled and seamed to mass produce articles of manufacture from the sheets such as food and beverage containers.

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Номер записи: 73
15-12-2020 дата публикации

blends of polystyrene and poly lactic acid

Номер: BR102013013965B1
Автор: Andréia Ossig, Augusto Cesar De Carvalho Peres, Cesar LIBERATO PETZHOLD, João Manoel Da Costa, Marcus Fernando Dal Pizzol, Vinícius Galhard Grassi
Принадлежит: Petróleo Brasileiro S/A - Petrobras, Universidade Federal Do Rio Grande Do Sul - UFRGS

BLENDAS DE POLIESTIRENO E POLI ÁCIDO LÁTICO São descritas blendas poliméricas de poliestireno (PS) e poli ácido lático (PLA) tendo adicionado um agente compatibilizante, preferencialmente um copolímero em bloco PS-PLA. Tais agentes compatibilizantes atuam controlando a separação de fases entre os componentes da blenda, não permitindo crescimento excessivo dos domínios de poliestireno dispersos na matriz de PLA, levando a obtenção de blendas com boa resistência térmica e mecânica. BLENDS OF POLYSTYRENE AND POLY LACTIC ACID Polymer blends of polystyrene (PS) and poly lactic acid (PLA) have been described having added a compatibilizing agent, preferably a PS-PLA block copolymer. Such compatibilizing agents act by controlling the phase separation between the components of the blend, preventing excessive growth of the polystyrene domains dispersed in the PLA matrix, leading to obtaining blends with good thermal and mechanical resistance.

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Номер записи: 74
27-07-1999 дата публикации

Laminated articles of manufacture fashioned from sheets having a highly inorganically filled organic polymer matrix

Номер: US5928741A
Автор: Per Just Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions, methods, and apparatus for manufacturing sheets having a highly inorganically filled matrix. Suitable inorganically filled mixtures are prepared by mixing together an organic polymer binder, water, one or more aggregate materials, fibers, and optional admixtures in the correct proportions in order to form a sheet which has the desired performance criteria. The inorganically filled mixtures are formed into sheets by first extruding the mixtures and the passing the extruded materials between a set of rollers. The rolled sheets are dried in an accelerated manner to form a substantially hardened sheet, such as by heated rollers and/or a drying chamber. The inorganically filled sheets may have properties substantially similar to sheets presently made from traditional materials like paper, paperboard, polystyrene, plastic, or metal. Such sheets can be rolled, pressed, scored, perforated, folded, and glued. They have especial utility in the mass production of containers, particularly food and beverage containers.

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Номер записи: 75
19-05-2016 дата публикации

Composition for preparing a nanostructured biodegradable polymeric material, the material obtained and its uses

Номер: ES2570655T3
Автор: Beneyto María Jordá, Blanca Miriam Gallur, Domingo Ana Galet, Mansilla Natalia Ortuño, Ramos Mercedes Hortal, Romero Susana Aucejo
Принадлежит: Inst Tecnologico Del Embalaje Transp Y Logistica Itene

Composición biodegradable para la preparación de un material polimérico biodegradable nanoestructurado, caracterizado por que comprende una mezcla de: i) homopolímero de poli(L-, D-lactida) (PLA) y, opcionalmente, homopolímero de poli(ε-caprolactona) (PCL), y ii) copolímero de dos bloques de poli(L-lactida) y poli(ε-caprolactona) (CPB), en la que este copolímero tiene una masa molar del bloque de L-lactida de entre 20.000 g/mol y 200.000 g/mol, y una masa molar del bloque de ε- caprolactona de entre 10.000 g/mol y 100.000 g/mol, siendo la proporción molar entre el bloque de L-lactida y el bloque de ε-caprolactona de 2:1. Biodegradable composition for the preparation of a nanostructured biodegradable polymeric material, characterized in that it comprises a mixture of: i) poly (L-, D-lactide) homopolymer (PLA) and, optionally, poly (ε-caprolactone) homopolymer (PCL ), and ii) two-block copolymer of poly (L-lactide) and poly (ε-caprolactone) (CPB), in which this copolymer has a molar mass of the L-lactide block of between 20,000 g / mol and 200,000 g / mol, and a molar mass of the ε-caprolactone block between 10,000 g / mol and 100,000 g / mol, the molar ratio between the L-lactide block and the ε-caprolactone block being 2: 1.

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Номер записи: 76
21-05-2003 дата публикации

Highly inorganically filled compositions

Номер: EP1308263A3
Автор: Per Just Andersen, Simon K Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions, methods, and apparatus for manufacturing sheets having a highly inorganically filled matrix prepared by mixing together an organic polymer binder, water, one or more inorganic aggregate materials, fibers, and optional admixtures in the correct proportions in order to form a sheet which has the desired performance criteria. The inorganically filled mixtures are formed into sheets by first extruding the mixtures and then passing the extruded materials between a set of rollers. The rolled sheets are dried in an accelerated manner to form a substantially hardened sheet, such as by heated rollers and/or a drying chamber. The inorganically filled sheets may have properties substantially similar to sheets presently made from traditional materials like paper, paperboard, polystyrene, plastic, or metal. Such sheets can be rolled, pressed, scored, perforated, folded, and glued. They have particular utility in the mass production of articles, such as food and beverage containers, and packaging materials.

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Номер записи: 77
11-10-2001 дата публикации

Compostable, degradable plastic compositions and articles thereof

Номер: WO2001074555A1
Автор: Norman L. Holy
Принадлежит: Holy Norman L

The present invention relates to thermoplastic compositions which are degradable and/or compostable, the method of preparation of the degradable and/or compostable compositions and use of the degradable and/or compostable compositions in a monofilament, shaped article or film, or may be used as a coating, e.g., of paper, to achieve a stronger article. These compositions have the advantage over existing biodegradable and compostable compositions by exhibiting a higher dimensional stability and comparatively low cost.

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Номер записи: 78
09-04-1996 дата публикации

Articles of manufacture fashioned from sheets having a highly inorganically filled organic polymer matrix

Номер: US5506046A
Автор: Per J. Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions, methods, and apparatus for manufacturing sheets having a highly inorganically filled matrix. Suitable inorganically filled mixtures are prepared by mixing together an organic polymer binder, water, one or more aggregate materials, fibers, and optional admixtures in the correct proportions in order to form a sheet which has the desired performance criteria. The inorganically filled mixtures are formed into sheets by first extruding the mixtures and then passing the extruded materials between a set of rollers. The rolled sheets are dried in an accelerated manner to form a substantially hardened sheet, such as by heated rollers and/or a drying chamber. The inorganically filled sheets may have properties substantially similar to sheets presently made from traditional materials like paper, paperboard, polystyrene, plastic, or metal. Such sheets can be cut, rolled, pressed, scored, perforated, folded, and glued to fashion articles from the sheets. They have especial utility in the mass production of containers, particularly food and beverage containers.

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Номер записи: 79
16-04-1996 дата публикации

Sheets having a highly inorganically filled organic polymer matrix

Номер: US5508072A
Автор: Per J. Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions and methods for manufacturing sheets having a highly inorganically filled matrix. Suitable inorganically filled mixtures are prepared by mixing together an organic polymer binder, water, one or more inorganic aggregate materials, fibers, and optional admixtures in the correct proportions in order to form a sheet which has the desired performance criteria. The inorganically filled mixtures are formed into sheets by first extruding the mixtures and the passing the extruded materials between a set of rollers. The rolled sheets are dried in an accelerated manner to form a substantially hardened sheet, such as by heated rollers and/or a drying chamber. The inorganically filled sheets may have properties substantially similar to sheets presently made from traditional materials like paper, paperboard, polystyrene, plastic, or metal. Such sheets can be rolled, pressed, scored, perforated, folded, and glued. They have especial utility in the mass production of containers, particularly food and beverage containers.

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Номер записи: 80
24-07-2018 дата публикации

Polystyrene and polylactic acid blends

Номер: US10030130B2
Автор: Andréia Ossig, Augusto Cesar De Carvalho Peres, Cesar LIBERATO PETZHOLD, João Manoel Da Costa, Marcus Fernando Dal Pizzol, Vinícius Galhard Grassi
Принадлежит: Petroleo Brasileiro SA Petrobras, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL UFRGS

Polymeric blends of polystyrene (PS) and polylactic acid (PLA) are described, in the preparation of which a compatibilizing agent was added, preferably a PS-PLA block copolymer. Such compatibilizing agents act controlling phase separation of the blending compounds, and preventing excessive growth of polystyrene domains scattered in the PLA matrix; and this results in blends with good mechanical and thermal resistance.

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Номер записи: 81
16-12-2004 дата публикации

Method of manufacturing embedded water soluble film carrier

Номер: US20040253434A1
Автор: Atikullah Saiyad, Shilpan Patel
Принадлежит: Patel Shilpan Pravinchandra, Saiyad Atikullah Hussainmiya

This invention relates to a water-soluble film (WSF) system with embedded/entrapped water-soluble films (WSF). More particularly, the invention relates to a WSF system with actives embedded/entrapped therein such as to provide precise and desired release of actives there from and its method of manufacturing for diverse applications, in which a variety of substances such as detergents, enzymes, softeners, perfumes, pesticides, fungicides, active ingredients, dyes, pigments, hazardous chemicals, active agents for cleaning laundry, dishes, floorings, walls, furniture, fluffs, pulp, etc., and the like can be so embedded/entrapped for such purpose. The invention further discloses novel online and offline process for the manufacture of such multi-layered WSF with or without liners and of desired shapes to selectively entrap interacting/non-interacting materials and their combinations. The process also provides options for the use of a wide range of raw materials, liners such as paper, film, foil, fabric, etc.

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Номер записи: 82
04-11-2009 дата публикации

Implants, device and method for joining tissue parts

Номер: KR100925073B1
Автор: 라우렌트 토리아니, 마르셀 애쉴리만, 안토니노 란치, 외르크 마이어
Принадлежит: 부트벨딩 아게

인간 또는 동물의 조직부, 특히 뼈로 양각 끼워맞춤 접속을 형성하기 위하여, 적어도 부분적으로 기계적 에너지에 의해 액화될 수 있는 재료로 구성되는 이식물(7)이 사용된다. 이러한 유형의 특히 적합한 재료는 열가소성수지(예를 들면, 재흡수가능한 열가소성수지) 또는 요변성 재료이다. 상기 이식물(7)은 상기 조직부와 접촉하도록 보내지고, 초음파 에너지의 작용을 받으며 동시에 상기 조직부에 대하여 압축된다. 그 다음 상기 액화가능 재료는 액화되고 상기 조직부의 구멍 또는 표면 굴곡부 속으로 압축되어 들어가고, 이에 따라, 일단 응결되면, 거기에 양각적으로 접합된다. 상기 이식은 제너레이터(2), 조화진동요소 및 공명기(6)을 포함하는 이식장치의 이용이 개입되고, 이것에 의해 상기 제너레이터(2)는 상기 조화진동요소를 기계적으로 조화진동하게 하며, 그리고 상기 요소는 상기 조화진동을 상기 공명기(6)으로 전달시킨다. 상기 공명기(6)는 상기 이식물(7)을 상기 조직부에 대해 압축하는데 사용되며 이것에 의해 조화진동이 상기 이식물(7)에 전달되게 한다. 상기 이식물(7)은 예를 들면, 핀형 또는 맞춤못 형상이고 뼈 조직과의 접속을 형성하기 위해 나사 대신에 사용되며, 이에 의해 상기 뼈 조직은 상기 이식물(7)을 위치시키기 위해 선택적으로 미리 구멍이 형성된다. 어떠한 토션 힘을 상기 이식물(7)에 전달할 필요가 없다는 사실에 의해, 이러한 이식물에는 더 약한 , 즉, 동일한 재료로 제작되는 공지된 나사로된 것보다 더 가는 구성이 제공될 수 있고, 그리고 이것은 더욱 신속하게 이식될 수 있다. In order to form an embossed fit connection into the tissue part of a human or animal, in particular bone, an implant 7 is used which consists of a material that can be liquefied at least in part by mechanical energy. Particularly suitable materials of this type are thermoplastics (eg, resorbable thermoplastics) or thixotropic materials. The implant 7 is sent to be in contact with the tissue portion, subjected to the action of ultrasonic energy and simultaneously compressed against the tissue portion. The liquefiable material is then liquefied and compressed into the holes or surface bends of the tissue, whereby once condensed, it is embossed to it. The implantation involves the use of an implantation device comprising a generator 2, a harmonic vibration element and a resonator 6, whereby the generator 2 mechanically oscillates the harmonic vibration element, and The element transmits the harmonic vibration to the resonator 6. The resonator 6 is used to compress the implant 7 against the tissue part whereby the harmonic vibrations are transmitted to the implant 7. The implant 7 is, for example, pin-shaped or dowel shaped and used in place of a screw to form a connection with bone tissue, ...

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Номер записи: 83
20-12-2014 дата публикации

Foil-free packaging laminate, method of production of packaging laminate and packaging containers produced from it

Номер: RU2535701C2
Автор: Магнус ВИЙК, Магнус РОБЕ, Нильс ТОФТ, Эва ЭРЕНБЕРГ
Принадлежит: ТЕТРА ЛАВАЛЬ ХОЛДИНГЗ ЭНД ФАЙНЭНС С.А.

FIELD: packaging industry. SUBSTANCE: material for induction heat sealing for packaging liquid products comprises a layer of paper or cardboard, outer liquid-impermeable heat sealable polymer layers based on polyolefins, and a vapour-deposited metal coating covering the inner side of the layer of paper or cardboard, sensitive to induction heating. EFFECT: invention enables creating the packaging material not containing aluminium foil for aseptic packaging of liquid products, which provides sufficient barrier properties of packaging containers for long-term aseptic storage under ambient conditions, which can be sealed using induction welding based on the mounted equipment for filling and sealing the packages. 18 cl, 12 dwg, 1 tbl РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 535 701 C2 (51) МПК B32B 27/10 (2006.01) B29C 65/00 (2006.01) B65D 85/72 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2012104241/05, 06.07.2010 (24) Дата начала отсчета срока действия патента: 06.07.2010 Приоритет(ы): (30) Конвенционный приоритет: (43) Дата публикации заявки: 20.08.2013 Бюл. № 23 (73) Патентообладатель(и): ТЕТРА ЛАВАЛЬ ХОЛДИНГЗ ЭНД ФАЙНЭНС С.А. (CH) R U 08.07.2009 SE 0900950-7 (72) Автор(ы): ТОФТ Нильс (SE), ВИЙК Магнус (SE), РОБЕ Магнус (SE), ЭРЕНБЕРГ Эва (SE) (45) Опубликовано: 20.12.2014 Бюл. № 35 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 08.02.2012 (86) Заявка PCT: EP 2010/004066 (06.07.2010) (87) Публикация заявки PCT: 2 5 3 5 7 0 1 (56) Список документов, цитированных в отчете о поиске: (см. прод.) 2 5 3 5 7 0 1 R U Адрес для переписки: 129090, Москва, ул. Б. Спасская, 25, строение 3, ООО "Юридическая фирма Городисский и Партнеры" (54) НЕ СОДЕРЖАЩИЙ ФОЛЬГИ УПАКОВОЧНЫЙ ЛАМИНИРОВАННЫЙ МАТЕРИАЛ, СПОСОБ ПРОИЗВОДСТВА УПАКОВОЧНОГО ЛАМИНИРОВАННОГО МАТЕРИАЛА И ИЗГОТОВЛЕННЫЙ ИЗ НЕГО УПАКОВОЧНЫЙ КОНТЕЙНЕР (57) Реферат: Изобретение относится к упаковочным бумаги или картона, чувствительное к ...

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Номер записи: 84
14-02-2012 дата публикации

Endoprostheses

Номер: US8114153B2
Автор: Afsar Ali, Jan Weber, Tom Holman
Принадлежит: Boston Scientific Scimed Inc

Endoprosthesis assemblies and methods of making endoprosthesis assemblies are disclosed. For example, endoprosthesis assemblies are described that include an endoprosthesis body and a polymeric coating about the endoprosthesis body. The polymeric coatings are engaged tightly to the endoprosthesis wall through engageable features created on the surface of the polymeric coatings and the surface of the endoprosthesis wall prior to engaging the surfaces.

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Номер записи: 85
06-11-2020 дата публикации

Preparation method of hyaluronic acid or salt particles thereof and obtained product

Номер: CN109531857B
Автор: 冯宁, 宗文斌, 石艳丽, 郭学平
Принадлежит: Bloomage Biotech Co Ltd, Shandong Huaxi Haiyu Biological Medicine Co Ltd

本发明公开了一种透明质酸或其盐颗粒的制备方法及所得产品，本发明所述的透明质酸颗粒制备方法为干法制粒法，将透明质酸或其盐粉末在不使用粘合剂的情况下经干法辊压造粒法辊压、粉碎、精细制粒、筛分、出料即得透明质酸或其盐颗粒。本发明产品具有堆积密度大、吸湿性弱、流动性好、稳定性好等特点，在使用过程中具有易于溶解、添加方便、减少了粉尘浪费和污染、长期储存和运输粉化率低等优点。本发明制备方法操作简单、需要的设备少、不需加粘合剂和辅料，对透明质酸或其盐的结构、性质无影响，可工业化生产。

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Номер записи: 86
27-09-2019 дата публикации

Microstructure for transdermal administration and a method for production thereof

Номер: RU2701361C1
Автор: Джэ Соо КИМ, Сан Джин ПАРК, Соон Чан КВОН
Принадлежит: Эндодерма Ко., Лтд.

FIELD: technological processes. SUBSTANCE: invention relates to a microstructure comprising a biocompatible polymer or adhesive and a method for production thereof. Microstructure contains a biocompatible polymer or adhesive, where the aspect ratio (w:h) including the diameter (w) of the lower surface of the microstructure and the height (h) of the microstructure ranges from 1:5 to 1:1.5, and the value of the angle of the distal tip is from 10° up to 40° and where multiple microstructures are arranged in the form of hexagon. In particular, microstructures from B-type to D-type according to the invention minimize resistance to penetration caused by skin elasticity, when combined with skin, thus increasing the penetration rate of structures (60 % or higher) and rate of absorption of useful ingredients into skin. Besides, microstructure of D-type according to invention maximally increases mechanical strength of structure due to use of triple structure and due to it can easily penetrate into skin. In case multiple microstructures have hexagonal arrangement, uniformly distributed pressure can be transferred to all microstructures on skin. EFFECT: invention optimizes the aspect ratio in accordance with the type of each of the microstructures, thereby providing the tip angle and the diameter range optimal for penetration through the skin. 18 cl, 27 dwg, 4 tbl РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 701 361 C1 (51) МПК A61M 37/00 (2006.01) B29C 39/02 (2006.01) B81C 1/00 (2006.01) C08L 101/16 (2006.01) C09J 201/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК A61K 47/36 (2019.02); A61K 47/38 (2019.02); A61K 9/0021 (2019.02); A61M 37/0015 (2019.02); B29C 39/02 (2019.02); B81B 1/008 (2019.02); B81C 1/00 (2019.02); B81C 1/00111 (2019.02); B81C 99/0085 (2019.02); C08B 15/04 (2019.02); C08B 37/0072 (2019.02); C08L 101/16 (2019.02); C09J 101/28 (2019.02); C09J 105/00 (2019.02); C09J 201/00 (2019.02) (24) Дата начала ...

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Номер записи: 87
21-07-1998 дата публикации

Method for manufacturing articles having inorganically filled, starch-bound cellular matrix

Номер: US5783126A
Автор: Per Just Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions, methods, and systems for manufacturing articles, particularly containers and packaging materials, having a particle packed, highly inorganically filled, cellular matrix are disclosed. Suitable inorganically filled mixtures are prepared by mixing together a starch-based binder, a solvent, inorganic aggregates, and optimal admixtures, e.g., fibers, mold-releasing agents, rheology-modifying agents, plasticizers, coating materials, and dispersants, in the correct proportions to form an article which has the desired performance criteria. The inorganically filled mixtures have a predetermined viscosity and are heated between molds at an elevated temperature and pressure to produce form-stable articles having a desired shape and a selectively controlled cellular, structure matrix. The molded articles may be placed in a high humidity chamber to obtain the necessary flexibility for their intended use. The articles may be manufactured to have properties substantially similar to articles presently made from conventional materials like paper, paperboard, polystyrene, plastic, or other organic materials. They have especial utility in the mass-production of containers, particularly food and beverage containers.

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Номер записи: 88
01-09-1998 дата публикации

Methods for manufacturing articles from sheets having a highly inorganically filled organic polymer matrix

Номер: US5800647A
Автор: Per Just Andersen, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions, methods, and apparatus for manufacturing sheets having a highly inorganically filled matrix. Suitable inorganically filled mixtures are prepared by mixing together an organic polymer binder, water, one or more aggregate materials, fibers, and optional admixtures in the correct proportions in order to form a sheet which has the desired performance criteria. The inorganically filled mixtures are formed into sheets by first extruding the mixtures and the passing the extruded materials between a set of rollers. The rolled sheets are dried in an accelerated manner to form a substantially hardened sheet, such as by heated rollers and/or a drying chamber. The inorganically filled sheets may have properties substantially similar to sheets presently made from traditional materials like paper, paperboard, polystyrene, plastic, or metal. Such sheets can be rolled, pressed, scored, perforated, folded, and glued. They have especial utility in the mass production of containers, particularly food and beverage containers.

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Номер записи: 89
22-09-1998 дата публикации

Methods for manufacturing molded sheets having a high starch content

Номер: US5810961A
Автор: Bruce J. Christiansen, Per Just Andersen, Shaode Ong, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions and methods for manufacturing sheets having a starch-bound matrix reinforced with fibers and optionally including an inorganic mineral filler. Suitable mixtures for forming the sheets are prepared by mixing together water, unmodified and ungelatinized starch granules, a cellulosic ether, fibers, and optionally an inorganic mineral filler in the correct proportions to form a sheet having desired properties. The mixtures are formed into sheets by passing them between one or more sets of heated rollers to form green sheets. The heated rollers cause the cellulosic ether to form a skin on the outer surfaces of the sheet that prevents the starch granules from causing the sheet to adhere to the rollers upon gelation of the starch. The green sheets are passed between heated rollers to gelatinize the starch granules, and then to dry the sheet by removing a substantial portion of the water by evaporation. The starch and cellulosic ether form the binding matrix of the sheets with the fibers and optional inorganic filler dispersed throughout the binding matrix. The starch-bound sheets can be cut, rolled, pressed, scored, perforated, folded, and glued to fashion articles from the sheets much like paper or paperboard. The sheets are particularly useful in the mass production of containers, such as food and beverage containers.

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Номер записи: 90
04-07-2000 дата публикации

Sheets having a starch-based binding matrix

Номер: US6083586A
Автор: Bruce J. Christensen, Per Just Andersen, Shaode Ong, Simon K. Hodson
Принадлежит: E Khashoggi Industries LLC

Compositions and methods for manufacturing sheets having a starch-bound matrix, optionally reinforced with fibers and optionally including an inorganic mineral filler. Suitable mixtures for forming the sheets are prepared by mixing together water, unmodified and ungelatinized starch granules, a cellulosic ether, optionally fibers, and optionally an inorganic mineral filler in the correct proportions to form a sheet having desired properties. The mixtures are formed into sheets by passing them between one or more sets of heated rollers to form green sheets. The heated rollers cause the cellulosic ether to form a skin on the outer surfaces of the sheet that prevents the starch granules from causing the sheet to adhere to the rollers upon gelation of the starch. The green sheets are passed between heated rollers to gelatinize the starch granules, and then to dry the sheet by removing a substantial portion of the water by evaporation. The starch and cellulosic ether form the binding matrix of the sheets with the fibers and optional inorganic filler dispersed throughout the binding matrix. The starch-bound sheets can be cut, rolled, pressed, scored, perforated, folded, and glued to fashion articles from the sheets much like paper or paperboard. The sheets are particularly useful in the mass production of containers, such as food and beverage containers.

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Номер записи: 91
28-02-2002 дата публикации

Highly inorganically filled compositions

Номер: KR100316469B1
Автор: 시몬케이.호드슨, 퍼저스트앤더슨
Принадлежит: 에쌈 카소기, 이. 카소기 인더스트리스,엘엘씨

유기 중합체 결합재, 물, 1종 이상의 무기 혼합재, 섬유재 및 임의의 혼합물제를 원하는 성능기준에 적합한 시이트를 형성하기에 적절한 양으로 함께 혼합함으로써 제조되는 고도로 무기물 충전된 매트릭스를 갖는 시이트를 제조하기 위한 조성물, 방법 및 장치가 제공된다. 무기물 충전된 혼합물은 먼저 혼합물(40)을 압출하고, 압출된 물질을 한 세트의 롤러(50) 사이로 통과시킴으로써 시이트로 형성된다. 압연된 시이트를 가열된 롤러 및/또는 건조실을 이용하여 가속적으로 건조시켜 실질적으로 경화된 시이트로 만든다. 무기물 충전된 시이트는 종이, 판지, 폴리스티렌, 플라스틱 또는 금속 같은 종래의 재료로 지금까지 만들어졌던 시이트와 실질적으로 유사한 성질을 가질 수 있다. 이러한 시이트는 감거나, 압축하거나, 새김선을 긋거나, 천공하거나, 접거나, 접착될 수 있다. 이들은 음식이나 음료 용기 및 포장재와 같은 물품의 대량생산에 특히 유용하다.

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Номер записи: 92
10-04-2015 дата публикации

Production of capsules of "core/envelope" type of various geometrical shapes and further processing

Номер: RU2547646C2
Автор: Георгиос Д. Карлес, Хосе Непомусено, Хунвэй ЛЮ, Шучжун Чжуан
Принадлежит: ФИЛИП МОРРИС ПРОДАКТС С.А.

FIELD: chemistry. SUBSTANCE: invention relates to multi-layered capsule, containing internal core, which includes first liquid composition of fragrance, internal envelope from first polymer material, at least, partially covering internal core; external envelope from second polymer material, at least partially covering internal envelope; and second liquid composition of fragrance, distributed in space between internal envelope and external envelope. EFFECT: reduction of travel and loss of fragrances. 15 cl, 6 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 547 646 C2 (51) МПК A24B 13/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2012145452/12, 28.03.2011 (24) Дата начала отсчета срока действия патента: 28.03.2011 Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): ЛЮ Хунвэй (US), КАРЛЕС Георгиос Д. (US), ЧЖУАН Шучжун (US), НЕПОМУСЕНО Хосе (US) (43) Дата публикации заявки: 10.05.2014 Бюл. № 13 R U (73) Патентообладатель(и): ФИЛИП МОРРИС ПРОДАКТС С.А. (CH) 26.03.2010 US 61/318,216 (45) Опубликовано: 10.04.2015 Бюл. № 10 B1, 28.04.2009. WO 2009094859 A1, 06.08.2009 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 26.10.2012 (86) Заявка PCT: IB 2011/000824 (28.03.2011) 2 5 4 7 6 4 6 (56) Список документов, цитированных в отчете о поиске: RU 2008102112 A, 27.07.2009. EA 11475 2 5 4 7 6 4 6 R U WO 2011/117727 (29.09.2011) Адрес для переписки: 129090, Москва, ул. Б. Спасская, 25, строение 3, ООО "Юридическая фирма Городисский и Партнеры" (54) ПРОИЗВОДСТВО КАПСУЛ ТИПА "ЯДРО/ОБОЛОЧКА" РАЗЛИЧНЫХ ГЕОМЕТРИЧЕСКИХ ФОРМ И ДАЛЬНЕЙШАЯ ОБРАБОТКА (57) Реферат: Изобретение относится к многослойной покрывающую внутреннюю оболочку; и вторую капсуле, содержащей внутреннее ядро, жидкую композицию ароматизатора, включающее первую жидкую композицию распределенную в пространстве между ароматизатора; внутреннюю оболочку из первого внутренней оболочкой и внешней оболочкой. полимерного материала, по меньшей ...

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Номер записи: 93
11-12-2014 дата публикации

Transplantation device and method of use

Номер: WO2014197798A2
Автор: Bhupinder S. SHERGILL, Elliot L. BOTVINICK, Jonathan R.T. LAKEY, Steven C. George
Принадлежит: The Regents of the University of California

Embodiments of the present disclosure relates to an implantable structure and a two stage method for cell and/or tissue transplantation. The implantable structure is configured to promote vascularization prior to cell and/or tissue transplantation, thereby allowing for implanted cells and/or tissues to have increased viability. In some embodiments, oxygen sensitive dyes can be used to determine levels of vascularization of the device.

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Номер записи: 94
01-09-2011 дата публикации

Natural polymer-based orthopedic fixation screw for bone repair and regeneration

Номер: CA2789784A1
Автор: Cato T. Laurencin, Sangamesh G. Kumbar
Принадлежит: University of Connecticut

A bone fixation device made of polysaccharide particles or microspheres fused into a solid structure is provided herein. The bone fixation device may be in the form of an orthopedic screw, orthopedic pin, or orthopedic plate. Methods of making the bone fixation devices described herein are provided as are methods of treating patients in need of bone repair or replacement by implanting a bone fixation device described herein in the patient at a site of bone damage, ligament damage, or bone deformity.

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Номер записи: 95
20-01-2008 дата публикации

Implants for making connections with tissues, namely, with skeleton, and device and method of implantation

Номер: RU2314768C2
Автор: Антонио Ланчи, Йорг МАЙЕР, Лоран ТОРРИАНИ, Марсель АЭСШЛИМАНН
Принадлежит: Вудвелдинг Аг

FIELD: medicine. SUBSTANCE: tissues are connected together by means of implants, or tissue connects with aids supporting or replacing tissue either with other auxiliary therapeutic devices. Implant is characterized by the fact that at least part of it is made of material turning to liquid state under effect of mechanical energy. Material, turning to liquid state, is placed onto implant in such a way that it can make contact with tissue and is capable of turning to excited state under effect of mechanical oscillations and be simultaneously pressed into tissue to liquefy at least part of material, which turns into liquid state, and is pressed into openings of tissue. Device for implanting implants 7 has oscillator 2, oscillation member and resonator 6. Oscillator 2 intends for excitation of mechanical oscillations in oscillation member. Resonator 6 and oscillation member form oscillation module 3. Resonator 6 actively connects with implant 7 to transmit mechanical oscillations and it intends for pressing implant 7 into tissue. Device also has guide of implant; casing or transmitting member has to be support for guide. Set is composed of oscillator 2, oscillation member and resonator 6. Oscillator 2 intends for exciting mechanical oscillations in oscillation member. Additional set with single implant or with more number of implants 7 has structures for implanting implants by means of energy of mechanical oscillations. Method of implantation of implants 7 by means of implantation device consists of following steps: positioning of implant onto tissue in such a way that areas of implants, made of material being capable of turning into liquid state, make contact or can make contact with tissue n point where there roughness or openings onto surface of tissue, which openings provide motionless connection, or in point where those roughness or openings can be formed by hydrostatic pressure; implant is subject to influence of mechanical oscillations followed by simultaneous ...

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Номер записи: 96
11-03-2010 дата публикации

Endoprostheses

Номер: US20100063584A1
Автор: Afsar Ali, Jan Weber, Tom Holman
Принадлежит: Boston Scientific Scimed Inc

Endoprosthesis assemblies and methods of making endoprosthesis assemblies are disclosed. For example, endoprosthesis assemblies are described that include an endoprosthesis body and a polymeric coating about the endoprosthesis body. The polymeric coatings are engaged tightly to the endoprosthesis wall through engageable features created on the surface of the polymeric coatings and the surface of the endoprosthesis wall prior to engaging the surfaces.

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Номер записи: 97
16-04-2007 дата публикации

IMPANTS AND DEVICE TO JOIN TISSUE PARTS.

Номер: ES2271212T3
Автор: Antonino Lanci, Jorg Mayer, Laurent Torriani, Marcel Aeschlimann
Принадлежит: WOODWELDING AG

Implante (7) para establecer una unión de ajuste positivo con una pieza de tejido, para unir ésta con otra pieza de tejido o con un elemento artificial que sustituya a otra pieza de tejido o la apoye, o que sea un dispositivo terapéutico auxiliar, consistiendo el implante (7) por lo menos parcialmente de un material licuable mediante energía mecánica, estando situado el material licuable en el implante (7) de tal manera que se pueda poner en contacto con la parte del tejido, se pueda excitar mediante vibraciones mecánicas y al mismo tiempo apretar contra la parte del tejido, con el fin de licuar por lo menos una parte del material licuable e inyectarlo en orificios de la parte del tejido. Implant (7) to establish a positive adjustment joint with a piece of tissue, to join it with another piece of tissue or with an artificial element that replaces another piece of tissue or supports it, or is an auxiliary therapeutic device, consisting the implant (7) at least partially of a liquefiable material by mechanical energy, the liquefiable material being located in the implant (7) so that it can be brought into contact with the tissue part, can be excited by mechanical vibrations and at the same time press against the part of the fabric, in order to liquefy at least a part of the liquefiable material and inject it into holes in the part of the fabric.

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Номер записи: 98
20-12-1999 дата публикации

Manufactured article, method of this article manufacture, system for this article manufacture

Номер: RU2142878C1
Автор: Пер Джаст АНДЕРСЕН, Симон Ходсон
Принадлежит: И. Хашиоджи Индастриес

FIELD: articles, methods and equipment for their manufacture. SUBSTANCE: invention includes manufacture of sheets having matrix filled with numerous inorganic substances produced by mixing of organic polymer binder, water, one or more inorganic aggregate materials, fibers and selected additional mixtures in preset proportions to obtain sheet with preset properties. Mixtures with inorganic substances are formed into sheets by the first extrusion of mixture and subsequent passing of extruded material through rolls. Sheets rolled by rolls are dried by accelerated method to obtain hardened sheet by rolling with hot rollers and/or in drying chamber. Sheets containing inorganic substances may have properties essentially similar to sheets manufactured from traditional such as paper, cardboard, polystyrene, plastic and metal. Such sheets may be rolled, pressed, marked, perforated, bent or cemented. Particularly, these sheets are applicable in mass manufacture of such articles as food containers and containers for beverages, and as packing materials. EFFECT: manufactured ecologically safe high-quality material and articles. 191 cl, 26 dwg ЗА СУСС ПЧ Го (19) РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ ВИ "” 2 142 878. (51) МПК 13) Сл В 28 В 21/00, 21/72, 0 21 Е 11/00, В 32 В 1/08 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 95114456/03, 24.11.1993 (24) Дата начала действия патента: 24.11.1993 (30) Приоритет: 25.11.1992 Ш$ 07/982 ,383 19.11.1993 1$ 08/152,354 19.11.1993 4$ 08/154,436 (46) Дата публикации: 20.12.1999 (56) Ссылки: Ц$ 4445970 А, 28.04.92. КУ 2062241 СЛ, 20.06.96. 54 1386026 АЗ, 30.03.88. КЦ 94043609 А\Л, 30.11.96. Ц$ 5108679 А, 28.04.92. 4$ 4895598 А, 23.01.90. 4$ 4093690 А, 06.06.78. ЕР 02004171 А, 05.11.86. УР 55-45511, 18.11.80. ЕК 2121551, 29.09.12. ЕК 2345912, 02.12.11. СВ 2099688, 15.12.82. (86) Заявка РСТ: 1$ 93/11490 (24.11.93) (87) Публикация РСТ: М/О 94/12328 (09.06.94) (98) Адрес для переписки: 113834, Москва, ...

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Номер записи: 99
15-04-2010 дата публикации

Foam medical devices and methods

Номер: WO2010042540A1
Автор: Jian Xin Guo, Kenton W. Gregory
Принадлежит: Providence And Biomedical Research Services, Inc., Providence Health System - Oregon

The invention provides a solid foam wound dressing useful for hemorrhage control and wound repair, as well as methods for making such a wound dressing.

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Номер записи: 100