Prodn. of carbonyl cpd. by oxidn. of alcohol with chloro-aromatic cpd.

Prodn. of carbonyl cpds. (I) comprises reacting the corresp. prim. or sec. alcohols (II) with a chlorinated aromatic cpd. (III) in presence of a complex transition metal catalyst (IV).

Glyoxyl-Cyclohexendione.

Verfahren zur Herstellung von Dicyclohexylaethanverbindungen

PROCESS FOR THE MANUFACTURE OF CYCLOHEXANE-1,3-DIONES AND 6 - ALKYL - 3,4 - DIHYDRO - 2 PYRANONES

GLYOXYL CYCLOHEXENDIONE ONE.

Procedure for the production of Adamantan-2-on

Carboxylic acid compound

Disclosed is a compound having a GPR40 agonistic activity and useful for use in a pharmaceutical composition or useful as an insulin secretion promoter or a prophylactic or therapeutic agent for diabetes. Extensive studies have been made on compounds having a GPR40 agonistic activity. As a result, it is found that a compound (I) having a carboxylic acid bound to the second or third ring moiety through a methylene group or having a benzene ring bound to the second or third ring moiety through a group –O-methylene -NH-methylene, wherein the benzene ring has been substituted by a 6-membered monocyclic aromatic ring, or a pharmaceutically acceptable salt of the compound (I) has an excellent GPR40 agonistic activity. It is also found that the compound has an excellent insulin secretion-promoting activity and can prevent the increase in a blood glucose level after glucose tolerance aggressively.

Apoptosis inhibitors

PROCESS FOR THE MANUFACTURE OF CYCLOHEXANE-1,3-DIONES AND 6-ALKYL-3,4-DIHYDRO-2-PYRANONES

Verfahren zur Herstellung von 3-(4'-Oxo-cyclohexen-2'-yl)-4-(3'-hydroxy-cyclopentyl)-hexan

Procédé de préparation du d-camphorate de 1-carnitinamide

2-1-methyl-4-oxo-cyclohexyl-3-1-methyl-3-oxo

Verfahren zur Herstellung von Adamantan-2-on und Abkömmlingen desselben

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[...][...][...] A [...][...] D' [...][...].

Substituted cyclohexanes

PROCESS FOR THE PREPARATION OF CYCLOHEXANE-DIONES -1,3-AND ALKYL 6-DIHYDRO -3,4-PYRANONES -2

DE-A-STEROIDS

NOUVEAUX COMPOSES LACTONIQUES ET LEUR APPLICATION EN PARFUMERIE

Nouveaux composés lactoniques et leur application en parfumerie. Les composés, le 3-cyclohexyl-pentanolide et le 4-cyclo-hexyl-pentanolide, répondent à la formule : ...

1,6-BIS(2-OXACYCLOHEXYL)-HEXANE-1,6-DIONES AND A PROCESS FOR PRODUCING THEM

Compounds and methods for altering lifespan of eukaryotic organisms

Provided are compounds which generally have a triketone structure. Examples of the compounds include derivatives of 1,3-cyclohexanedione, such as: 1,3-cyclohexanedione, 2-propanoyl-5-cyclohexyl-; 1,3-cyclohexanedione, 2-propanoyl-5-[4-fluorophenyl]-; 1,3-cyclohexanedione, 2-acetyl-5-[thien-2-yl]-; 1,3-cyclohexanedione, 2-acetyl-5-butyl-; and 1,3-cyclohexanedione, 2-propanoyl-5-[bicyclo[2.2.1]hept-2-en-5-yl]-. The compounds can be used to alter the lifespan of eukaryotic organisms and treat inflammation.

CYCLOPENTANONE DERIVATIVE

A novel cyclopentanone derivative having a cyclopentanone or cyclopentanol ring having substituents at the 2- and 5-positions is provided. The cyclopentanone derivative preferably has 13 to 17 carbon atoms. A perfume composition comprising the cyclopentanone derivative emits a flora fragrance emphasizing a natural and fresh feeling. It is useful for perfuming a variety of toiletries and households. A process for preparing the above-mentioned cyclopentanone derivative is also provided by which the cyclopentanone derivative can be obtained in a practically acceptable yield.

CYCLOHEXANE DERIVATIVES

MIXTURE OF MATRIX MATERIAL AND ORGANIC SEMICONDUCTOR CAPABLE OF EMISSION, USE THEREOF, AND ELECTRONIC COMPONENT CONTAINING THE MIXTURE

PROBLEM TO BE SOLVED: To provide a new material and a mixture of materials of an organic electronic component such as an electroluminescent element, and use thereof in a display based thereon. SOLUTION: The invention relates to a new mixture consisting of at least two materials, one material being used as a matrix material (for example, spirobifluorene represented by the figure) and the other as a material which is capable of emission and contains at least one element of an atomic number of 20 or larger. The mixture is used in the organic electronic component such as an electroluminescent element and a display. COPYRIGHT: (C)2012,JPO&INPIT ...

CYCLOHEXANE DERIVATIVES

Verfahren zur Herstellung von Ketonen

Verfahren zur Umlagerung von 8-Oxytricyclodecen-(4) in 8-Ketotricyclodekan

Preparation of diketodicarboxylic acids

... 1,062,351. Diketodicarboxylic acids. GEIGY (U.K.) Ltd. Feb. 14, 1966 [Feb. 17, 1965], No. 6745/65. Heading C2C. The invention comprises diketo-dicarboxylic acids of formula wherein the groups R are the same and each is hydrogen, or a methyl group; salts and esters thereof, in particular 7,12-dioxo-octadecane 1,18-dioic acid and 2,17-dimethyl-7,12-dioxooctadecane-1,18-dioic acid, and a process of preparation in which a tetraketone of formula is hydrolysed. The tetraketone may be heated with aqueous alkali, preferably an aqueou alkali metal hydroxide.

Organic compounds

Procedure for the production of the new 3 (4 ' - Oxocyclohexen-2' yl) - 4 (of 3 ' - hydroxycyclopentyl) - hexane

SPIROCYCLI KETOLE AND THEIR USE

CYCLIC AMINO ACIDS AND THEIR DERIVATIVES AS DRUGS

METHODS FOR MAKING RETINOIDS AND USES THEREOF

... ²²²Described herein are methods for making retinoids. Also described herein are ²retinoids and methods of use thereof.² ...

CARBOXYLIC ACID COMPOUND

[Problem] The present invention has an object to provide a compound having a GPR40 agonistic activity, which is useful as a pharmaceutical composition, an insulin secretion promoter, or an agent for preventing/treating diabetes. [Means for Solution] The present inventors have extensively studied a compound having a GPR40 agonistic activity, and as a result, they have found that the compound (I) of the present invention or a pharmaceutically acceptable salt thereof, in which a carboxylic acid is bonded to a bicyclic or tricyclic moiety through methylene, and further, a benzene ring substituted with a monocyclic 6-membered aromatic ring is bonded to a bicyclic or tricyclic moiety through -O-methylene or -NH-methylene, has an excellent GPR40 agonistic activity. They have also found that the compound has an excellent insulin secretion promoting action and strongly inhibits increase in the blood glucose after glucose loading, thereby completing the present invention.

CERTAIN GLYOXYL-CYCLOHEXENDIONES

ABSTRACT CERTAIN GLYOXYL-CYCLOHEXENDIONES Compounds of formula I

Céto-carboxylic acids and their preparation

Manufactoring process of products of condensation

CETÓIS ESPIROCÍCLICOS E SEU USO

CYCLOHEXANE DERIVATIVES

Cyclohexane derivatives of formula R1-A1-Z1-A2-R2 in which R1 and R2 in each case are H, an alkyl group with 1-10 C atoms, in which also one or two non-neighboring CH2 groups can be replaced by O atoms and/or -CO groups and/or -CO-O groups and/or -CH=CH groups, F, Cl, Br, CN or R3-A3-Z2-, A1 is -A-, A4-Zo-A- or -A-Zo-A4-, A is an unsubstituted cyclohexylene group, or a trans-1,4-cyclohexylene or 1,4-cyclohexenylene group substituted in 2nd, 3rd, 5th and/or 6th position once, or more than once by F and/or Cl and/or Br and/or CN and/or an alkyl group or a fluoridated alkyl group, each having 1-10 C atoms, in which also one or two non-neighboring CH2 groups can be replaced by O atoms and/or -CO groups and/or -CO-O groups, which cyclohexylene or cyclohexenylene group, as the case may be, also can be substituted in the 1st or 4th position, in which one or two CH2 groups are replaced by -CO-, or R1-A1- is a cyclohexyl group substituted in 3rd position by an alkyl group with 1-10 C atoms, in which ...

Process for producing alicyclic diketone compounds

There is provided a process for producing an alicyclic diketone compound represented by the formula (1) wherein X is a single bond, -CH -, -C(CH ) -, -O- or -SO -, R and R² each represents an alkyl group having 1 to 6 carbon atoms, m and n are 0 to 2, comprising dehydrogenating an alicyclic diol compound represented by the formula (2) wherein X, R , R², m and n are as defined above in a liquid phase in the presence of at least one member selected from the group consisting of copper type catalysts and Raney type catalysts.

ПАРОКСЕТИН ХОЛАТ ИЛИ СОЛИ ПРОИЗВОДНЫХ ХОЛЕВОЙ КИСЛОТЫ И КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ПАРОКСЕТИН И ХОЛЕВУЮ КИСЛОТУ ИЛИ ПРОИЗВОДНЫЕ ХОЛЕВОЙ КИСЛОТЫ

FIELD: chemistry. SUBSTANCE: claimed invention describes paroxetine cholate or salt of cholic acid derivative and composition, which contains paroxetine and cholic acid or its derivative. Also described is pharmaceutical composition for treatment of depressive states, containing paroxetine salt or composition. Pharmaceutical composition can be part of peroral medication, swallowed without water, on form of disintegrating in mouth paroxetine tablet. EFFECT: obtaining paroxetine cholate or salt of cholic acid derivative, which can be used in pharmacology. 19 cl, 38 ex, 12 tbl

ПРОИЗВОДНОЕ КАРБОНОВОЙ КИСЛОТЫ

1. Соединение формулы (1) или его соль[Хим. 1](в которойL представляет собой О или NH,Rпредставляет собой Н или низший алкил,X представляет собой 1,2-фенилен или -Z-C(R)(R)-,Z представляет собой О или CH,Rи Rобъединены друг с другом с образованием Салкилена, который может быть замещен,R, R, R, R, Rи Rявляются одинаковыми или отличаются друг от друга и представляют собой Н, галоген, низший алкил, который может быть замещен, или -О-(низший алкил, который может быть замещен),Rпредставляет собой H, OH, -О-(гетероциклическую группу, которая может быть замещена) или -O-(CRR)-R,Rи Rявляются одинаковыми или отличаются друг от друга и представляют собой Н, ОН, галоген, или низший алкил, который может быть замещен илиRи Rобъединены друг с другом с образованием оксо (=О),n равно 1, 2, 3 или 4,Rпредставляет собой H, OH, галоген, NRR, -SO-(низший алкил, который может быть замещен), арил, который может быть замещен, -О-(низший алкил, который может быть замещен) или гетероциклическую группу, которая может быть замещена,Rи Rявляются одинаковыми или отличаются друг от друга и представляют собой H, -SO-(низший алкил, который может быть замещен) или низший алкил, который может быть замещен,R, Rи Rявляются одинаковыми или отличаются друг от друга и представляют собой H, галоген, низший алкил, который может быть замещен, или -О-(низший алкил, который может быть замещен),Yи Yявляются одинаковыми или отличаются друг от друга и представляют собой N или С-RиRпредставляет собой Н, галоген, низший алкил, который может быть замещен, или -О-(низший алкил, который может быть замещен)).2. Соединение формулы (I') или его соль[Хим. 2](в которойL представляет собой О или NH,Rпредставляет собой Н или низший алкил,X предста� РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК C07C 43/225 (13) 2011 147 232 A (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2011147232/04, 21.04.2010 (71) Заявитель(и): АСТЕЛЛАС ФАРМА ИНК. (JP) Приоритет(ы): (30) ...

ПРОИЗВОДНЫЕ ГЛИОКСИЛ-ЦИКЛОГЕКСЕНДИОНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ГЕРБИЦИДНАЯ КОМПОЗИЦИЯ, СПОСОБ ПОДАВЛЕНИЯ НЕЖЕЛАТЕЛЬНОГО РОСТА РАСТЕНИЙ

FIELD: organic chemistry. SUBSTANCE: invention proposes compounds of the formula (I): $$$ which were used as herbicides exhibiting effect with respect to dicotyledonous weed, methods of their synthesis and using. EFFECT: improved method of synthesis, enhanced effectiveness of herbicides. 6 cl, 4 tbl ЭУ5 ООС ПЫ Го (19) РИ (11) 2 100 346 (13) Сл ОМК © 07С 49/603, 49/172, 49/175, А 01 М 35/06 РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 4830743/04, 19.07.1990 (71) Заявитель: Шелл Интернэшнл Рисерч Маатсхаппий Б.В. (30) Приоритет: 21.07.1989 ОЕ Р 39242412 (МЫ) (46) Дата публикации: 27.12.1997 (72) Изобретатель: Ханс Иоахим Биссингер[ОЕ], | Людвиг Шредер[ОЕ], Хельмут 49/784, 1987. 2. ЗИ, патент, 1209016, кл. А Фрусторфер[ОЕ] Манфред Гарех ОЕ] 01 М 31/06, 1982. () (73) Патентообладатель: Шелл Интернэшнл Рисерч Маатсхаппий Б.В. (Ме) < (54) ПРОИЗВОДНЫЕ ГЛИОКСИЛ-ЦИКЛОГЕКСЕНДИОНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ГЕРБИЦИДНАЯ < КОМПОЗИЦИЯ, СПОСОБ ПОДАВЛЕНИЯ НЕЖЕЛАТЕЛЬНОГО РОСТА РАСТЕНИЙ < (57) Реферат: которые находят использование в © Предложены соединения формулы 1: качестве гербицидов, эффективных против двудольных сорняков, способы их получения © и использования. 5 з.п. ф-лы, 4 табл. == Сс' — О Эт 0О0б0гс ПЧ Го (19) КУЗЗАМ АСЕМСУ ГОК РАТЕМТ$ АМО ТКАОЕМАКК$ 12) АВЗТКАСТ ОЕ 1МУЕМТОМ ВИ “” 2400 346 ' (51) 1пЕ. С1.6 13) Сл С 07С 49/603, 49/172, 49/175, А 01 М 35/06 (21), (22) АррИсаНоп: 4830743/04, 19.07.1990 (30) Рпогйу: 21.07.1989 ОЕ Р 3924241.2 (46) Рае ог рибИсаНоп: 27.12.1997 (72) |пуетог: (71) АррИсапе: эре! |егпейзпп! Кизегсй МааКварри В.М. (МЕ) КПап$ 1оакКМт Вззтаег[ОЕ], Циама эпгедегоЕ], Кпе’тще ВаЧгизпа ОЕ], ЕПК Кадда [ОЕ], Мо Чдапа ЕгиЗогег[ОЕ], Маптеа Сагекп ОЕ] (73) Ргорпеюг: эпе! \егпейзйп! К зегсй МааКПарри В.М. (МЕ) (54) РДЕКМАТМЕЗ$З ОЕ СЕУОХУЕ-СУСЕОНЕХЕМЕОЮМЕ, МЕТНОО ОЕ ТНЕКВ ЗУМТНЕ$!$, НЕКВСТОЕ СОМРОЗГОМ, МЕТНОО ОЕ \МЕЕО 1МНВГОМ (57) АБЗгасЕ: НЕГО: огдапс спептгу. ЗОВЗТАМСЕ: пуепНоп ...

DEKALINCARBONITRILE

New derivative of 1,3,4-metheno-2h-cyclobuta (cd) pentalen-2-ol

The invention comprises decachlorooctahydro - 1,3,4 - methano - 2H - cyclobuta (cd) pentalen-2-ol of the formula also carbamates, inorganic ester or organic monocarboxylic esters thereof. The alcohol is prepared by refluxing the corresponding ketone with a metallic hydride in the presence of an inert solvent under substantially anhydrous conditions at a temperature of 50 DEG to 175 DEG C. Any metallic hydride may be used but NaBH4 and LiAlH4 are preferred. The solvent may be an aromatic hydrocarbon or a high boiling ether. The alcohol may be converted into its derivatives by conventional methods and numerous examples are given.ALSO:A pesticidal composition comprises decachlorooctahydro - 1,3,4 - methano - 2H - cyclobuta (cd) pentalen-2-ol of the formula or a carbamate, inorganic ester or organic monocarboxylic ester thereof together with a solid or liquid carrier or diluent. Liquid compositions may contain 10% to 25% of active ingredient with an ...

Cyclohexylcyclopentane derivatives

... 1,130,935. Cyclohexylcyclopentane derivatives. BEECHAM GROUP Ltd. 23 Oct., 1967 [28 Oct., 1966], No. 48425/66. Heading C2C. The invention comprises compounds of the formula where R 1 and R 2 are alkyl of 1-6 carbon atoms or complete a 5- or 6-membered carbooyclic ring, R 3 and R 4 are H or together complete an additional bond and X is (H, OH) an oxygen atom or the group -YCH 2 CH 2 Y- where Y is O or S. The compounds are prepared by reducing compounds of the formula where X1 is as defined for X and R 5 is H or alkyl of 1-6 carbon atoms by using metallic lithium in liquid ammonia and then treating with oxalic acid to give a product wherein R 3 and R 4 form a bond, and if desired, catalytically hydrogenating to give a product wherein R 3 and R 4 are H, and if desired, oxidizing a compound in which X is H, OH to the ketone, and if desired, when X is a ketal or thioketal group, removing this group by hydrolysis to give the ketone.

DE-A-STEROIDS

... 1374850 De-A-steroids, 4,5-secosteroids F HOFFMANN-LA ROCHE & CO AG 10 Nov 1972 [12 Nov 1971] 52027/72 Heading C2C The invention relates to compounds of formula wherein R1 is 3-oxobutyl, ketalized 3-oxobutyl, 3-chloro-2-butenyl, 3-methyl-2-butenyl, 3- (C 1 -C 6 alkoxy)-2-butenyl, 3-hydroxybutyl (or an ester or ether thereof), 2-carboxyethyl, 2-cyanoethyl, 2-(C 2 -C 6 alkoxycarbonyl)-ethyl or a 4-isoxazolylmethyl group bearing a C 1 -C 6 alkyl substituent in at least one of positions 3 and 5; and D is a group of formula wherein m is 1 or 2; R2 is free, esterified or etherified hydroxy; R3 is H, C 1 -C 6 alkyl or C 2 -C 6 alkynyl; or R2 and R3 together represent a ketal, ethylidene, 1-(C 1 -C 6 alkanoyloxy)- ethylidene or bis-(methylenedioxy)ethyl group; R4 is H or OH; R5 is oxo, ketal, (H, OH), (H, esterified OH) or (H, etherified OH); R6 is H or free, esterified or etherified OH; or R4 and R6 may together ...

PROCEDURE FOR THE PRODUCTION OF DEA STEROIDEN

Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures

The present invention discloses mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures. The invention relates to novel mixtures consisting of at least two substances, one substance being used as a matrix material and the other as a material which is capable of emission and contains at least one element having an atomic number larger than 20. The invention also relates to the use of said mixtures in organic electronic components such as electroluminescence elements and displays.

ANTIBACTERIAL COMPOUNDS

There is an ongoing need for new antibiotics which may be effective against bacteria that are otherwise difficult to control. The present invention therefore relates to new antibacterial triketone compounds of Formula (1), or salts, metal complexes or tautomeric forms of these compounds. The compounds have potential as novel antibiotics. Thus, the invention also relates to methods of treatment or prevention of bacterial infections using the compounds, and to compositions containing them.

Cyclic amino acids and derivatives thereof useful as pharmaceutical agents

The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

TRANS-DECALINCARBONITRILES

NEW ODORIFEROUS COMPOUNDS

SUBSTITUIERTE CYCLOHEXANE

Cyclohexyl-pentanolides their use and process for preparing same

New lactones having the formula (I) wherein the cyclohexyl radical is bound to the carbon atoms at position 3 or 4 as indicated by the dotted lines, their use as perfuming ingredients and process for their preparation.

CYCLOHEXANE DERIVATIVES AND THIS CONTAINING LIQUIDCRYSTALLINE COMPOSITION

NOUVEAUX CYCLOHEXANES SUBSTITUES UTILES COMME AGENTS OLFACTIFS

L'invention concerne des composés chimiques nouveaux. Il s'agit des composés de formule ...

MIXTURES OF MATRIX MATERIALS AND ORGANIC SEMICONDUCTORS CAPABLE OF EMISSION, USE OF THE SAME AND ELECTRONIC COMPONENTS CONTAINING SAID MIXTURES

The invention relates to novel mixtures consisting of at least two substances, one substance being used as a matrix material and the other as a material which is capable of emission and contains at least one element having an atomic number larger than 20. The invention also relates to the use of said mixtures in organic electronic components such as electroluminescence elements and displays.

Cyclic amino acids and derivatives thereof useful as pharmaceutical agents

The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

CYCLOHEXANE DERIVATIVES

Cyclohexane derivatives of formula R1-A1-Z1-A2-R2 in which R1 and R2 in each case are H, an alkyl group with 1-10 C atoms, in which also one or two non-neighboring CH2 groups can be replaced by O atoms and/or -CO groups and/or -CO-O groups and/or -CH=CH groups, F, Cl, Br, CN or R3-A3-Z2-, A1 is -A-, A4-Zo-A- or -A-Zo-A4-, A is an unsubstituted cyclohexylene group, or a trans-1,4-cyclohexylene or 1,4-cyclohexenylene group substituted in 2nd, 3rd, 5th and/or 6th position once, or more than once by F and/or Cl and/or Br and/or CN and/or an alkyl group or a fluoridated alkyl group, each having 1-10 C atoms, in which also one or two non-neighboring CH2 groups can be replaced by O atoms and/or -CO groups and/or -CO-O groups, which cyclohexylene or cyclohexenylene group, as the case may be, also can be substituted in the 1st or 4th position, in which one or two CH2 groups are replaced by -CO-, or R1-A1- is a cyclohexyl group substituted in 3rd position by an alkyl group with 1-10 C atoms, in which ...

VERFAHREN ZUR HERSTELLUNG EINER BRASSYLSAEUREDIESTER-VORSTUFE UND VON BRASSYLSAEUREDIESTER

Improvements in and relating to pesticides

As active components of pesticides, particularly of insecticides, use is made of addition products of dialkyl or diaryl malonates with decachloro-octahydro - 1,3,4 - metheno - 2H - cyclobuta(cd)pentalen - 2 - one, to which is assigned the cage formula (see Division C2). The addition products are said to have the formula The products may be formulated as liquid compositions or wettable powders with the aid of liquid or solid diluents, a number of which are specified. Examples and experimental results are given.

DIHYDROXY PEROXY BICYCLOALKANES

... 1427363 Dihydroxy peroxy bicycloalkanes BP CHEMICALS INTERNATIONAL Ltd 10 Dec 1973 [12 Jan 1973] 1740/73 Heading C2C The invention comprises compounds of the formula where X is an alkylene radical containing between 3 and 5 carbon atoms in the chain forming a ring with the adjacent carbon atoms C1 or C1' and C2' and a process for the preparation thereof comprising reacting in the liquid phase a bi(cycloalkane-2-one) with hydrogen peroxide. The bi(cycloalkane-2-one) starting material is prepared by reacting the corresponding monoketone with nickel peroxide optionally in the presence of a suitable solvent. Examples are furnished.

Derivative of carnitinamide and process for preparing the same

The novel d-camphorate salt of l-carnitinamide is prepared by fractional crystallization of an alcoholic solution of the d-camphorate of dl-carnitinamide, the desired compound being obtained as the first fraction to crystallize. The d-camphorate of dl-carnitinamide may be prepared by treating a dl-carnitinamide halide in an aqueous or alcoholic medium with silver d-camphorate, or by treating a dl-carnitinamide halide in an aqueous or alcoholic medium with silver hydroxide, and reacting the product with d-camphoric acid. Silver d-camphorate may be prepared by treating ammonium d-camphorate, obtained by reacting d-camphoric acid with ammonium hydroxide, with a water-soluble silver salt. l-Carnitinamide chloride is obtained by treating an ethanolic solution of the d-camphorate of l-carnitinamide with ether saturated with hydrogen chloride.

Methods for making retinoids and uses thereof

APOPTOSIS INHIBITORS

Apoptosis inhibitors containing as the active ingredient compounds represented by general formula (I) or salts thereof, wherein W1 represents -O-, -CH2-, etc.; W2 represents -CH2-, etc.; W3 represents -O-, -CH2-, etc.; X represents CH, C-, etc.; and A represents formula (.alpha.) wherein W4 represents -O-, -CH2-, etc.; W5 represents -CH2-, etc.; and W6 represents -O-, -CH2-, etc. These apoptosis inhibitors inhibit apoptosis of WC8 cells induced by Fas ligand. In animal models, they potently inhibit the progress of fulminant hepatitis and relieve alopecia caused by anticancer agents. Because of being highly safe, these apoptosis inhibitors are usable as beneficial drugs.

PROCESS FOR THE PREPARATION OF CYCLOHEXANE-DIONES -1,3-AND ALKYL 6-DIHYDRO -3,4-PYRANONES -2

D-camphorate of 1-carnitinamide and its method of preparation

CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME

A liquid crystalline compound which has a low viscosity and is electrically and chemically stable and compatible with other known liquid crystalline compounds at low temperatures, and a liquid crystal composition containing the same, which compound is a phenyl-4-cyclohexylbutylcyclohexane derivative expressed by the formula: <CHEM> wherein R represents a hydrogen atom a linear or branched alkyl group of 1 to 15 carbon atoms, and X1, X2 and X3 are each independent and X1 and X3 each represent a hydrogen atom or a halogen atom and X2 represents a hydrogen atom or a linear or branched alkyl group of 1 to 15 carbon atoms (wherein one -CH2CH2- bond may be replaced by a -CH=CH-bond and one non-adjacent -CH2- bond may be replaced by an oxygen atom), a halogen atom, a cyano group, a trifluoromethyl group or a trifluoromethoxy group.

CYCLIC AMINO ACIDS AND DERIVATIVES THEREOF USEFUL AS PHARMACEUTICAL AGENTS

The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

Disubstituted cycloalkanones as fragrance materials

Disubstituted cycloalkanones are prepared from one of 2-cyclopentylidenecyclopentan-1-one, 2-cyclohexylidenecyclohexan-1-one, 2-cyclopentylidenecyclohexan-1-one, or 2-cyclohexylidenecyclopentan-1-one. The resulting compounds were analyzed for their odor characteristics. The different compounds exhibited varied odor characteristics, which were not predictable from the structures of the compounds. The compounds are useful in the preparation of fragrance compositions and products formed from same.

High-purity cyclopentanone derivatives, process for preparing same, and perfume composition

A composition comprising at least 60% by weight, based on the weight of the composition, of a cyclopentanone or cyclopentanol compound having 2,5-dicyclopentylidene substituents, 2,5-dicyclopentyl substituents or 2-cyclopentylidene-5-cyclopentyl substituents. This composition is useful as perfume emitting floral fragance. 2,5-Dicyclopentylidenecyclopentanone (compound 4) is prepared by reaction of 2-cyclopentylidenecyclopentanone with cyclopentanone. 2,5-Dicyclopentylcyclopentanone (compound 5) and 2,5-dicyclopentylidenecyclopentanol (compound 6) are prepared by reduction of compound 4. 2,5-Dicyclopentylcyclopentanol (compound 7) is prepared by reduction of compound 5 or compound 6.

ПАРОКСЕТИН ХОЛАТ ИЛИ СОЛИ ПРОИЗВОДНЫХ ХОЛЕВОЙ КИСЛОТЫ И КОМПОЗИЦИЯ СОДЕРЖАЩАЯ ПАРОКСЕТИН И ХОЛЕВУЮ КИСЛОТУ ИЛИ ПРОИЗВОДНЫЕ ХОЛЕВОЙ КИСЛОТЫ

ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß (19) RU (11) 2006 104 241 (13) A (51) ÌÏÊ C07D 405/12 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÇÀßÂÊÀ ÍÀ ÈÇÎÁÐÅÒÅÍÈÅ (21), (22) Çà âêà: 2006104241/04, 28.12.2004 (71) Çà âèòåëü(è): ×îíã Êóí Äàíã Ôàðìàñüþòèêë Êîðï. (KR) (30) Êîíâåíöèîííûé ïðèîðèòåò: 21.09.2004 KR 10-2004-0075458 (43) Äàòà ïóáëèêàöèè çà âêè: 20.12.2007 Áþë. ¹ 35 (87) Ïóáëèêàöè PCT: WO 2006/033250 (30.03.2006) Àäðåñ äë ïåðåïèñêè: 101000, Ìîñêâà, Öåíòð, à/ 732, Àãåíòñòâî ÒÐÈÀ ÐÎÁÈÒ, ïàò.ïîâ. Ã.Ì.Âàøèíîé R U ÑÎÄÅÐÆÀÙÀß ÏÀÐÎÊÑÅÒÈÍ È ÕÎËÅÂÓÞ ÊÈÑËÎÒÓ ÈËÈ ÏÐÎÈÇÂÎÄÍÛÅ ÕÎËÅÂÎÉ ÊÈÑËÎÒÛ (57) Ôîðìóëà èçîáðåòåíè 1. Ïàðîêñåòèí õîëàò èëè ñîëü ïðîèçâîäíîãî õîëåâîé êèñëîòû, â êîòîðîé õîëåâà êèñëîòà è åå ïðîèçâîäíîå îòâå÷àþò ôîðìóëå 1 A 2 0 0 6 1 0 4 2 4 1 A (54) ÏÀÐÎÊÑÅÒÈÍ ÕÎËÀÒ ÈËÈ ÑÎËÈ ÏÐÎÈÇÂÎÄÍÛÕ ÕÎËÅÂÎÉ ÊÈÑËÎÒÛ È ÊÎÌÏÎÇÈÖÈß ãäå R1, R2 è R3 íåçàâèñèìî âë þòñ àòîìàìè âîäîðîäà èëè ãèäðîêñèëüíûìè ãðóïïàìè, à Õ îáîçíà÷àåò -ÎÍ, -ONa, -NH-(CH2)n-SO3H, -NH-(CH2)n-SO3Na, -NH-(ÑÍ2)n-SO3Ê, -NH(CH2)n-CO2H, -NH-(CH2)n-CO2Na èëè -NH-(CH2)n-CO2K (ãäå n öåëîå ÷èñëî îò 1 äî 3), èëè ôîðìóëå 2 Ñòðàíèöà: 1 RU 2 0 0 6 1 0 4 2 4 1 (86) Çà âêà PCT: KR 2004/003477 (28.12.2004) R U (85) Äàòà ïåðåâîäà çà âêè PCT íà íàöèîíàëüíóþ ôàçó: 06.06.2006 (72) Àâòîð(û): ËÈ Ñàíã Äæîîí (KR), ×ÈÍ Õåå Äæîíã (KR), ÊÈ Ìèí Õèî (KR), ËÈ Ñó Êèîíã (KR), ÊÈÌ Áîê ßíã (KR), ËÈ Õîíã Âîî (KR) A 2 0 0 6 1 0 4 2 4 1 A R U 2 0 0 6 1 0 4 2 4 1 ãäå R1, R2 è R3 íåçàâèñèìî âë þòñ àòîìàìè âîäîðîäà èëè ãèäðîêñèëüíûìè ãðóïïàìè, è Õ îáîçíà÷àåò -ÎÍ. -ONa. -NH-(CH2)n-SO3H, -NH-(CH2)n-SO3Na, -NH-(ÑÍ2)n-SO3Ê, -NH(CH2)n-CO2H, -NH-(CH2)n-CO2Na èëè -NH-(CH2)n-CO2K (ãäå n öåëîå ÷èñëî îò 1 äî 3), èëè ôîðìóëå 2 R U ãäå Õ èìååò çíà÷åíè , ïðèâåäåííûå â ôîðìóëå 1. 2. Ñîëü ïî ï.1, â êîòîðîé ñîëü âë åòñ ñîëüþ ïàðîêñåòèí õîëàòà. 3. Ñîëü ïî ï.1 èëè 2, â êîòîðîé ñîëü ïàðîêñåòèíà íàõîäèòñ â êðèñòàëëè÷åñêîé ôîðìå. 4. Ñîëü ïî ï.1 èëè 2, â êîòîðîé ñîëü ïàðîêñåòèíà íàõîäèòñ â íåêðèñòàëëè÷åñêîé ôîðìå. 5. Ôàðìàöåâòè÷åñêà ...

Cyclohexanderivate und diese enthaltende flüssigkristalline Zusammensetzung

Tetraketones

The invention comprises tetraketones of formula wherein the groups R are the same and each is a hydrogen or a methyl group, specifically, 1,6-bis(2-oxocyclohexyl)hexane-1,6-dione, and 1,6-bis(2- oxo - 5 - methyl cyclohexyl)hexane -1,6dione, 1,6-bis(2 - oxo - 5 - methyl cyclohexyl)hexane -1,6-dione, and a process for the preparation thereof by reacting adipoyl dichloride with an excess over the stoichiometric preparation of an enamine of a cyclohexanome of formula The enamine may be derived from a secondary cyclic amine such as morpholine.

PROCESSES FOR PREPARING A BRASSYLIC DIESTER

ANTIBACTERIAL COMPOUNDS

Cyclic amino acids and derivatives thereof useful as pharmaceutical agents

CERTAIN GLYOXYL-CYCLOHEXENDIONES

Cyclohexane compound and liquid crystal composition containing said compound

Process for the preparation of 3 - (4 'Oxo-cyclohexen -2' -yl) - 4 - (3' hydroxycyclopentyl)-hexane

A method for fighting parasites using a new additive and a method for preparing this additive

Method of preparation of derived from adamantane

Cyclohexane derivative and liquid crystal composition containing the same

A liquid crystalline compound which has a low viscosity and is electrically and chemically stable and compatible with other known liquid crystalline compounds at low temperatures, and a liquid crystal composition containing the same, which compound is a phenyl-4-cyclohexylbutylcyclohexane derivative expressed by the formula: ##STR1## wherein R represents a hydrogen atom or a linear or branched alkyl group of 1 to 15 carbon atoms, and X 1 , X 2 and X 3 are each independent and X 1 and X 3 each represent a hydrogen atom or a halogen atom and X 2 represents a hydrogen atom or a linear or branched alkyl group of 1 to 15 carbon atoms (wherein one --CH 2 CH 2 -- bond may be replaced by a --CH═CH-- bond and one non-adjacent --CH 2 -- bond may be replaced by an oxygen atom), a halogen atom, a cyano group, a trifluoromethyl group or a trifluoromethoxy group.

Alpha-hydroxyalkyl-4-tertiary-alkylcyclohexane perfume compositions

Novel α-hydroxyalkyl-4-t-alkylcyclohexanes possessing a sandalwood note, their utility as olfactory agents, and perfume compositions containing them.

Verfahren zur Herstellung von 3-(4'-Oxo-cyclohexyl)-4-(3'-oxo-cyclohexyl)-hexan

SUBSTITUTED CYCLOHEXANES

Novel alpha -hydroxyethyl-4-t-alkylcyclohexanes of the general formula in which R1 represents a tert-C6- or C7-alkyl radical, where the tert- C atom is bonded to the cyclohexane ring, and a process for the preparation of these novel compounds I are described. The novel compounds I have sandalwood notes and can therefore be used as perfumes, e.g. in the preparation of perfume compositions.

CYCLIC AMINO ACIDS AND DERIVATIVES THEREOF USEFUL AS PHARMACEUTICAL AGENTS

The invention is a novel series of cyclic amino acids which are useful in th e treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

4-Oxocyclohexyl-3-Oxocyclopentyl-Alkanes and a process for preparing them

PROCESS FOR THE PREPARATION OF UN DESA-STEROIDS

Mixture of organic emission-enabled semiconductors and matrix materials, use of same and electronic components containing same

A mixture contains a matrix material containing specified units; and a material which is capable of emission and which contains an element of atomic number above 20. A mixture contains (a) a matrix material containing units of formula C:Q where Q = a non-bonding electron pair comprising O, S, Se or N; and (b) a material which is capable of emission and which contains an element of atomic number above 20. An independent claim is also included for novel aromatic or heteroaromatic compounds of formulae (10a)-(15). [Image] Z : CR 1> or N; Y : N; R 1> - R 3> which must be different from each other : (a) H, CN, optionally cyclic 1-40C alkyl, alkoxy or alkylamino optionally with one or more non-adjacent -CH 2- groups replaced by -R 4>C=CR 4>-, -Ctriple boundC-, C=O, C=S, C=Se, C=NR 4>, -O-, -S-, -NR 5>- or -CONR 6>- and optionally with one or more H replaced by F, Cl, Br or I or (b) a 1-40C (hetero)aromatic system optionally with one or more H replaced by F, Cl, Br or I and optionally substituted by one or more non- aromatic residue R 1> where one or more R 1> and/or R 1>, R 2> are on the same or different rings or stretch between a mono and poly-cyclic aliphatic or aromatic ring system; and R 4> - R 6>H or 1-20C aliphatic or aromatic hydrocarbon; Ar : a 2- 40C (hetero)aromatic system optionally with one or more H replaced by F, Cl, Br or I and optionally substituted with one or more non-aromatic residue R 1> as per (b) above; n : 0 or 1; E : C or N; R 7>(a) 1-40C alkyl, alkoxy or alkylamino optionally with one or more non-adjacent -CH 2- groups replaced by -R 4>C=CR 4>-, -C=C-, C=O, C=S, C=Se, C=NR 4>, -O-, -S-, -NR 4>- or -CONR 4>-; (b) an aromatic group optionally substituted by halogen, alkyl, -CF 3, -OH, -SH, -S-alkyl, alkoxy, - NO 2, -CN, -COOH, -COOAlkyl, -NH 2, -Nalkyl, benzyl or benzoyl; or (c) a 2-40C large aromatic system optionally with one or more H replaced by F, Cl, Br or I and optionally ...

Disubstituierte Cycloalkanone als Riechstoffe

CYCLOHEXANE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME

The present invention intends to provide a novel cyclohexane compound that can form a liquid crystal composition of which response speed is improved when mixed with a nematic liquid crystal and the like and to provide a specified liquid crystal composition in which a novel cyclohexane compound is mixed. The novel cyclohexane compound is represented by the following formula (1). 5. A liquid crystal composition comprising:{'claim-ref': [{'@idref': 'CLM-00003', 'claim 3'}, {'@idref': 'CLM-00004', 'claim 4'}], 'the liquid crystal composition of mixed with at least one kind of a compound of a compound group of the formula (7) of .'}6. A liquid crystal composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'one or two or more kinds of the cyclohexane compound groups of .'}7. Use of the liquid crystal composition described in in an electrooptical application.8. An electrooptical display device comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'the liquid crystal composition of encapsulated in a liquid crystal cell.'} The present invention relates to a novel cyclohexane compound and a liquid crystal composition containing the new cyclohexane, and intends to improve the response speed of a liquid crystal display.Many liquid crystal display devices that make use of the optical anisotropy (Δn) (hereinafter, referred to as “Δn” in some cases) or the dielectric constant anisotropy (Δε) (hereinafter, referred to as “Δε” in some cases), which are features of a liquid crystal compound, have been manufactured and have been used in watches, calculators, measurement instruments, instrument panels for vehicles, word processors, electronic diaries, portable telephones, printers, computers, TVs and so on. A liquid crystal compound used in liquid crystal display devices has a specific liquid crystal phase, and the phase mode thereof can be roughly divided into a nematic phase, a smectic phase and a cholesteric phase. Among these, a nematic phase is most widely ...

Compounds and Methods for Altering Lifespan of Eukaryotic Organisms

Provided are compounds which generally have a triketone structure. Examples of the compounds include derivatives of 1,3-cyclohexanedione, such as: 1,3-cyclohexanedione, 2-propanoyl-5-cyclohexyl-; 1,3-cyclohexanedione, 2-propanoyl-5-[4-fluorophenyl]-; 1,3-cyclohexanedione, 2-acetyl-5-[thien-2-yl]-; 1,3-cyclohexanedione, 2-acetyl-5-butyl-; and 1,3-cyclohexanedione, 2-propanoyl-5-[bicyclo[2.2.1]hept-2-en-5-yl]-. The compounds can be used to alter the lifespan of eukaryotic organisms and treat inflammation. 11.) The compound of claim 1 , wherein the compound is selected from the following: 1 claim 1 ,3-cyclohexanedione claim 1 , 2-acetyl-5-[4-(N claim 1 ,N-dimethylamino)phenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-cyclopentanecarbonyl-5-[4-methylphenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-cyclopentanecarbonyl-5-[4-(1-methylethyl)phenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-cyclopentanecarbonyl-5-[4-chlorophenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-cyclopentanecarbonyl-5-[fur-2-yl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-isobutyryl-5-[fur-2-yl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-benzoyl-5-[2-chloro-6-fluorophenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-propanoyl-5-[4-methoxyphenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-acetyl-5-[3 claim 1 ,4-dimethoxyphenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-benzoyl-5-[3 claim 1 ,4-dimethoxyphenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-acetyl-5-[naphth-2-yl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-benzoyl-5-[2 claim 1 ,4-dichlorophenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-propanoyl-5-[2 claim 1 ,4 claim 1 ,5-trimethoxyphenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-benzoyl-5-[4-fluorophenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-benzoyl-5-[4-methoxyphenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-benzoyl-5-[fur-2-yl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2-cyclopropanecarbonyl-5-[4-methoxyphenyl]-; 1 claim 1 ,3-cyclohexanedione claim 1 , 2- ...

CYCLIC AMINO ACIDS AND DERIVATIVES OF THE SAME, USEFUL AS PHARMACEUTICAL AGENTS

Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures

본 발명은 하나의 물질이 매트릭스 재료로서 이용되고, 다른 하나는 방출가 가능하고 원자 번호 20 초과인 하나 이상의 원소를 함유하는 물질로서 이용되는, 2 개 이상의 물질로 이루어진 신규 혼합물에 관한 것이다. 본 발명은 또한 전계발광 요소 및 디스플레이와 같은 유기 전자 부품에서의 상기 혼합물의 용도에 관한 것이다. The present invention relates to a novel mixture of two or more materials in which one material is used as the matrix material and the other is capable of being released and containing one or more elements having an atomic number greater than 20. The invention also relates to the use of said mixture in organic electronic components such as electroluminescent elements and displays.

Polycyclic phenols, alcohols and ketones from phenols, cyclic alcohols and cyclic ketones using a nickel oxide/manganese oxide/magnesium oxide catalyst in presence of at least one of hydrogen and nitrogen

At least one of a polycyclic phenol, a polycyclic alcohol and a polycyclic ketone is produced under hydrogenation conditions using a nickel oxide/manganese oxide/magnesium oxide catalyst by subjecting at least one of a monocyclic ketone, a monocyclic alcohol and a monocyclic phenol to said conditions and said catalyst.

Mixture of matrix material and organic semiconductor capable of emitting light, use thereof, and electronic component comprising said mixture

A mixture contains a matrix material containing specified units; and a material which is capable of emission and which contains an element of atomic number above 20. A mixture contains (a) a matrix material containing units of formula C:Q where Q = a non-bonding electron pair comprising O, S, Se or N; and (b) a material which is capable of emission and which contains an element of atomic number above 20. An independent claim is also included for novel aromatic or heteroaromatic compounds of formulae (10a)-(15). [Image] Z : CR1> or N; Y : N; R1> - R3> which must be different from each other : (a) H, CN, optionally cyclic 1-40C alkyl, alkoxy or alkylamino optionally with one or more non-adjacent -CH2- groups replaced by -R4>C=CR4>-, -Ctriple boundC-, C=O, C=S, C=Se, C=NR4>, -O-, -S-, -NR5>- or -CONR6>- and optionally with one or more H replaced by F, Cl, Br or I or (b) a 1-40C (hetero)aromatic system optionally with one or more H replaced by F, Cl, Br or I and optionally substituted by one or more non- aromatic residue R1> where one or more R1> and/or R1>, R2> are on the same or different rings or stretch between a mono and poly-cyclic aliphatic or aromatic ring system; and R4> - R6>H or 1-20C aliphatic or aromatic hydrocarbon; Ar : a 2- 40C (hetero)aromatic system optionally with one or more H replaced by F, Cl, Br or I and optionally substituted with one or more non-aromatic residue R1> as per (b) above; n : 0 or 1; E : C or N; R7>(a) 1-40C alkyl, alkoxy or alkylamino optionally with one or more non-adjacent -CH2- groups replaced by -R4>C=CR4>-, -C=C-, C=O, C=S, C=Se, C=NR4>, -O-, -S-, -NR4>- or -CONR4>-; (b) an aromatic group optionally substituted by halogen, alkyl, -CF3, -OH, -SH, -S-alkyl, alkoxy, - NO2, -CN, -COOH, -COOAlkyl, -NH2, -Nalkyl, benzyl or benzoyl; or (c) a 2-40C large aromatic system optionally with one or more H replaced by F, Cl, Br or I and optionally substituted by one or more non- ...

Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures

The present invention describes new types of material mixtures composed of at least two substances, one serving as a matrix material and the other being an emission material capable of emission, the latter comprising at least one element of atomic number greater than 20, and the use thereof in organic electronic components such as electroluminescent elements and displays.

Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures

Mischungen von organischen zur Emission befähigten Halbleitern und Matrixmaterialien, deren Verwendung und Elektronikbauteile enthaltend diese Mixtures of organic emission-capable semiconductors and matrix materials, their use and electronic components containing them Die vorliegende Erfindung beschreibt neuartige Materialmischungen aus mindestens zwei Substanzen, wobei die eine als Matrixmaterial dient und die andere ein zur Emission befähigtes Emissionsmaterial ist, welches mindestens ein Element der Ordungszahl größer 20 enthält, und deren Verwendung in organischen elektronischen Bauteilen wie Elektrolumineszenzelementen und Displays. The present invention describes novel mixtures of materials comprising at least two substances, one serving as a matrix material and the other being an emission material capable of emitting at least one element of the order number greater than 20, and their use in organic electronic components such as electroluminescent elements and displays.

Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures

Die vorliegende Erfindung beschreibt neuartige Materialmischungen aus mindestens zwei Substanzen, wobei die eine als Matrixmaterial dient und die andere ein zur Emission befähigtes Emissionsmaterial ist, welches mindestens ein Element der Ordungszahl grösser 20 enthält, und deren Verwendung in organischen elektronischen Bauteilen wie Elektrolumineszenzelementen und Displays.

Mixture of organic emission-enabled semiconductors and matrix materials, use of same and electronic components containing same

Die vorliegende Erfindung beschreibt neuartige Materialmischungen aus mindestens zwei Substanzen, wobei die eine als Matrixmaterial dient und die andere ein zur Emission befähigtes Emissionsmaterial ist, welches mindestens ein Element der Ordungszahl größer 20 enthält, und deren Verwendung in organischen elektronischen Bauteilen wie Elektrolumineszenzelementen und Displays. The present invention describes novel material mixtures of at least two substances, one serving as a matrix material and the other being an emission material capable of emitting which contains at least one element of order number greater than 20 and their use in organic electronic components such as electroluminescent elements and displays.

Mixtures of organic semiconductors capable of emission and matrix materials, their use and electronic components containing them

Mischungen enthaltend- mindestens ein Matrixmaterial A gemäß Formel (1), Formel (2), Formel (3), Formel (10) oder Formel (11), welches A eine Glastemperatur Tg(gemessen als Reinsubstanz) größer 70 °C aufweist,wobei die Symbole und Indizes folgende Bedeutung haben:X ist O;Y ist N;Z ist gleich oder verschieden bei jedem Auftreten CR1oder N,R1, R2, R3ist gleich oder verschieden bei jedem Auftreten eine geradkettige oder verzweigte oder cyclische Alkyl- oder Alkoxygruppe mit 1 bis 40 C-Atomen, wobei ein oder mehrere nicht benachbarte CH2-Gruppen durch -O-, -S-, -NR5- oder -CONR6- ersetzt sein können und wobei ein oder mehrere H-Atome durch F ersetzt sein können, oder eine Aryl- oder Heteroarylgruppe mit 1 bis 40 C-Atomen, wobei ein oder mehrere H-Atome durch F, Cl, Br, I ersetzt sein können und die durch einen oder mehrere, nicht aromatische Reste R1substituiert sein kann;R5, R6sind gleich oder verschieden bei jedem Auftreten, H oder ein aliphatischer oder aromatischer Kohlenwasserstoffrest mit 1 bis 20 C-Atomen; und- mindestens ein zur Emission befähigtes Emissionsmaterial B, welches eine Verbindung ist, die bei geeigneter Anregung Licht emittiert und mindestens ein Atom aus der Gruppe Iridium oder Platin enthält. Mixtures containing at least one matrix material A according to formula (1), formula (2), formula (3), formula (10) or formula (11), which A has a glass transition temperature Tg (measured as pure substance) greater than 70 ° C, wherein the symbols and indices have the following meanings: X is O; Y is N; Z is identically or differently on each occurrence CR1 or N, R1, R2, R3 is identically or differently on each occurrence a straight-chain or branched or cyclic alkyl or alkoxy group with 1 up to 40 carbon atoms, where one or more non-adjacent CH2 groups can be replaced by -O-, -S-, -NR5- or -CONR6- and where one or more H atoms can be replaced by F, or one Aryl or heteroaryl group with 1 to 40 carbon atoms, where one or more H atoms can be replaced by F, Cl, ...

Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures

本发明公开了基质材料和能够发光的有机半导体的混合物、其用途和含有所述混合物的电子元件。具体地，本发明公开由至少两种物质组成的新型材料混合物，一种物质用作基质材料，另一种物质是能够发光的发光材料，发光材料包括至少一种原子数大于20的元素，也公开了该混合物在有机电子元件如电致发光元件和显示器中的用途。

NEW SUBSTITUTE CYCLOHEXANES USEFUL AS OLFACTORY AGENTS

L'invention concerne des composés chimiques nouveaux. Il s'agit des composés de formule : The invention relates to novel chemical compounds. These are compounds of formula:

Patent FR2415108B1

PROCESS FOR THE PREPARATION OF A LOWER ALKYL DIESTER OF BRASSYLIC ACID

L'INVENTION CONCERNE UN NOUVEAU PROCEDE DE PREPARATION D'UN DIESTER D'ALKYLE INFERIEUR DE L'ACIDE BRASSYLIQUE DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST UN GROUPE ALKYLE INFERIEUR. SELON L'INVENTION, ON FAIT REAGIR UN PERACIDE AVEC LA 2,2-METHYLENEBISCYCLOHEXANONE DANS UN SOLVANT ORGANIQUE HALOGENE EN PRESENCE D'UN CARBONATE ALCALIN POUR FORMER LE 6,6-METHYLENEBIS-(6-HEXANOLIDE) ET ON EFFECTUE L'HYDROCRAQUAGE DUDIT HEXANOLIDE DANS UN ALCOOL DE FORMULE:ROHDANS LAQUELLE R EST TEL QUE DEFINI CI-DESSUS, EN PRESENCE D'UN CATALYSEUR METALLIQUE ET D'UN CATALYSEUR ACIDE. THE INVENTION CONCERNS A NEW PROCESS FOR PREPARING A LOWER ALKYL DIESTER OF BRASSYLIC ACID OF GENERAL FORMULA: (CF DRAWING IN BOPI) IN WHICH R IS A LOWER ALKYL GROUP. ACCORDING TO THE INVENTION, A PERACID IS REACTED WITH 2,2-METHYLENEBISCYCLOHEXANONE IN A HALOGENIC ORGANIC SOLVENT IN THE PRESENCE OF AN ALKALINE CARBONATE TO FORM 6,6-METHYLENEBIS- (6-HEXANOLIDE) AND THE HYDROCRACKING PERFORMED. HEXANOLIDE IN AN ALCOHOL OF FORMULA: ROHD IN WHICH R IS AS DEFINED ABOVE, IN THE PRESENCE OF A METAL CATALYST AND AN ACID CATALYST.

CYCLIC AMINO ACIDS AND DERIVATIVES AS MEDICAMENTS

Cyclic amino acids and derivatives thereof which are useful as pharmaceutical agents

Patent JPS6126766B2

Highly reactive forms of zinc and reagents thereof

A novel zerovalent zinc species and an organozinc reagent are disclosed. The zerovalent zinc species is directly produced by reaction of a reducing agent on a zinc salt, preferably Zn(CN)2. The organozinc reagent results from the reaction of the zerovalent zinc species and an organic compound having one or more stable anionic leaving groups. These organozinc reagents include a wide spectrum of functional groups in the organic radical, and are useful in a variety of reaction schemes.

Cyclohexane compound and liquid crystal composition containing said compound

Cyclohexane compound and liquid crystal composition containing the same

The present invention intends to provide a novel cyclohexane compound that can form a liquid crystal composition of which response speed is improved when mixed with a nematic liquid crystal and the like and to provide a specified liquid crystal composition in which a novel cyclohexane compound is mixed. The novel cyclohexane compound is represented by the following formula (1). (In the formula (1), R 1 and R 2 represent the same or different R, ROCO or RCOO, and the R represents an alkyl group. The alkyl group may have an unsaturated bond, and, in the group, —CH 2 — may be substituted with —O—, —CO— or —COO—, and a part of or an entirety of hydrogen atoms may be substituted with a halogen atom or a cyano group. X and Y each independently represents a halogen atom or a hydrogen atom and does not simultaneously represent a hydrogen atom. Further, alternatively, X represents an oxygen atom and Y represents a direct bond to the oxygen atom.)

Methods for making retinoids and uses thereof.

Se describen metodos para formar retinoides. Tambien se describen retinoides y metodos de uso de los mismos.

Cyclohexanone oxime derivatives, process for their preparation and further processing to cyclohexanone derivatives

CYCLIC AMINO ACIDS AND DERIVATIVES AS MEDICAMENTS

Carbon monoxide prodrugs for the treatment of medical disorders

The present invention provides new compounds and compositions thereof that release carbon monoxide for the treatment of medical disorders that are responsive to carbon monoxide, for example, inflammatory, pain, and dermatological disorders.

CYCLINE AMINOACIDS AND ITS DERIVATIVES USED AS PHARMACEUTICAL AGENTS.

Un compuesto de fórmula (Ver fórmula) o una sal farmacéuticamente aceptable del mismo en la que: R es hidrógeno o un grupo lineal o ramificado de 1 a 4 átomos de carbono, R9 a R14 son seleccionados independientemente cada uno de hidrógeno, alquilo lineal o ramificado de 1 a 6 carbonos, fenilo, bencilo, flúor, cloro, bromo, hidroxi, hidroximetil, amino, aminometil, trifluorometil, -CO2H, -CO2R15, -CH2CO2H, -CH2CO2R15, -OR15 en el que R15 es un alquilo lineal o ramificado de 1 a 6 carbonos, fenilo, o bencilo, y R1 a R8 no son hidrógeno simultáneamente. A compound of formula (See formula) or a pharmaceutically acceptable salt thereof in which: R is hydrogen or a linear or branched group of 1 to 4 carbon atoms, R9 to R14 are each independently selected from hydrogen, linear alkyl or branched from 1 to 6 carbons, phenyl, benzyl, fluorine, chlorine, bromine, hydroxy, hydroxymethyl, amino, aminomethyl, trifluoromethyl, -CO2H, -CO2R15, -CH2CO2H, -CH2CO2R15, -OR15 in which R15 is a linear alkyl or branched from 1 to 6 carbons, phenyl, or benzyl, and R1 to R8 are not hydrogen simultaneously.

GLIOXYL-SYCLOHEXENE-DIONS OF DIKOTILEDONE TO BE USED AS HERBICIDE, EFFECTIVE TO HERBS.

Process for prolonging the smell of perfumed substances

Antibacterial compounds

There is an ongoing need for new antibiotics which may be effective against bacteria that are otherwise difficult to control. The present invention therefore relates to new antibacterial triketone compounds of Formula (1), or salts, metal complexes or tautomeric forms of these compounds. The compounds have potential as novel antibiotics. Thus, the invention also relates to methods of treatment or prevention of bacterial infections using the compounds, and to compositions containing them.

New cyclobutane derivatives, useful as components of liquid crystal media for liquid crystal displays, reflective or trans-reflective displays and electro-optical displays

New cyclobutane derivatives with mesogenic groups attached to a cyclobutane ring with a carbonyl or optionally halogenated methylene group or two chlorine or fluorine atoms at position 2 and optionally an alkyl or methylene group at position 3. Cyclobutane derivatives of formula (I) are new. R<1> = H, CN, F, OCHF2, OCF3, OCHFCF3, OCH2CF3, OCF2CF3 or 1-12C alkyl (optionally substituted with halogen or CN and optionally with one or more non-adjacent CH2 groups replaced by O, S, CO, cyclobutane-1,3-diyl, COO, OCO, OCOO or CH=CH groups); Q = C=O, CCl2, CF2 or C=CX<1>X<2>; X<1>, X<2> = H, Cl or F; Y = CHR<2> or (if Q = CCl2 or CF2) also C=CHR<2>; R<2> = H or 1-12C alkyl (optionally with CH2 group(s) replaced as above); A, A<1> = (a) trans-1,4-cyclohexylene, optionally with one or more non-adjacent CH2 groups replaced by O and/or S, (b) 1,4-phenylene, optionally with one or two CH groups replaced by N; (c) 1,4-bicyclo(2.2.2)octylene, piperidine-1,4-diyl, naphthalene-2,6-diyl or its decahydro- or 1,2,3,4-tetrahydro derivatives, or (d) 1,4-cyclohexenylene, where groups (a), (b) and (d) may also be substituted with CN, Cl or F; Z<1> = COO, OCO, CH2O, O, OCH2, CH2CH2, CH=CH, C equivalent to C or a single bond; and m = 1, 2 or 3. Independent claims are also included for: (a) liquid crystal (LC) media with at least two LC components, containing at least one compound (I); (b) LC display elements containing such media; and (c) reflective or trans-reflective LC display elements

Herbicide

2-acetyl-7-methoxy -1,2,3,4,9,10-hexahydro-phenanthrene- - produced by dehydration process

1-Vinyl-1-hydroxy-6-methoxy-1,2,3,4-tetraydrophthalene is dehydrated using halogen and 1-vinyl-6-methoxy-3,4-dihydronaphthalene produced is reacted with methyl vinyl ketone and title cpd. is then produced by isomerisation of the intermediate i.e. 2-acetyl-7-methoxy-1,2,3,9,10,10a hexahydrophenanthrene using halogen, pref. iodine.

Cyclic amino acids and derivatives thereof useful as pharmaceutical agents.

SPIROCYCLIC KETOLE AND ITS USE

Cyclic amino acids and their derivatives useful as pharmaceuticals

Cyclic amino acids and their derivatives useful as pharmaceuticals

Cyclohexane compound and liquid crystal composition containing said compound

네마틱 액정 등에 혼합하여, 응답 속도를 개량한 액정 조성물을 형성할 수 있는 신규 시클로헥산 화합물을 제공함과 함께, 신규 시클로헥산 화합물이 혼합된 특정 액정 조성물을 제공하는 것이다. 이 신규 시클로헥산 화합물을 이하의 식 (1) 에 나타낸다. (식 (1) 중 R 1 , R 2 는 동일 또는 상이한 R, ROCO, RCOO 를 나타내고, R 은 알킬기를 나타낸다. 그 알킬기는 불포화 결합을 갖고 있어도 되고, 그 기 중 -CH 2 - 는 -O-, -CO- 또는 -COO- 로 치환되어 있어도 되고, 또한, 일부 혹은 전부의 수소 원자가 할로겐 원자 또는 시아노기에 의해 치환되어 있어도 된다. X, Y 는 각각 독립적으로 할로겐 원자 또는 수소 원자를 나타내고, 동시에 수소 원자를 나타내는 경우는 없다. 또한, X 는 산소 원자를 나타내고 Y 는 그 산소 원자에 대한 직접 결합을 나타낸다) To provide a novel cyclohexane compound capable of forming a liquid crystal composition improved in response speed by mixing with a nematic liquid crystal or the like, and to provide a specific liquid crystal composition in which a novel cyclohexane compound is mixed. This novel cyclohexane compound is shown in the following formula (1). (Wherein R 1 and R 2 represent the same or different R, ROCO, and RCOO, and R represents an alkyl group. The alkyl group may have an unsaturated bond, and -CH 2 - , -CO- or -COO-, and some or all of the hydrogen atoms may be substituted by a halogen atom or a cyano group, X and Y each independently represents a halogen atom or a hydrogen atom, and at the same time And X represents an oxygen atom and Y represents a direct bond to the oxygen atom.

Cyclohexanone-oxime derivatives, method for their preparation as well as method for their further processing into cyclohexanone- and cyclohexylamine derivatives

Spirocyclic ketols and their use

Described are spirocyclic ketols of formula (I) wherein n and A have the same meaning as given in the description. Also disclosed is a method for their production and flavour and fragrance compositions containing them.

Process for the manufacture of cyclohexane-1,3-diones and 6-alkyl-3,4-dihydro-2-pyranones

Cyclohexane-1,3-diones of the formula ##STR1## having up to 24 carbon atoms are prepared in admixture with 6-alkyl-3,4-dihydro-2-pyranones of the formula ##STR2## having up to 24 carbon atoms, in which formulae the radicals R and R' may be identical or different and represent each a hydrogen atom, an alkyl, a cycloalkyl or an aryl group each having up to 12 carbon atoms and the two radicals R' together optionally represent a --(CH 2 ) 3 -group, by passing 4-oxocarboxylic acids of the formula ##STR3## having up to 24 carbon atoms and in which R and R' have the above meaning at a temperature of from 250° to 500° C in the gaseous phase over a dehydration catalyst and the pyranones are converted into cyclohexane-1,3-diones by passing them in the gaseous phase over a dehydration catalyst at a temperature of from 250° to 500° C.

Mixtures for use in organic electronic devices of simplified layer structure comprise matrix materials (some of which in e.g. (hetero)aromatic ketone form are new) and emitters containing an element of atomic number above 20

Die vorliegende Erfindung beschreibt neuartige Materialmischungen aus mindestens zwei Substanzen, wobei die eine als Matrixmaterial dient und die andere ein zur Emission befähigtes Emissionsmaterial ist und welches mindestens ein Element der Ordnungszahl größer 20 enthält, und deren Verwendung in organischen elektronischen Bauteilen wie Elektrolumineszenzelementen und Displays.

Cyclohexane compound and liquid crystal composition containing said compound

Cyclic amino acids and derivatives useful for pharmaceutical use

Method of producing adamantane-2-one

Decachlorooctahyro-1,3,4-metheno-2H-cyclobuta(c,d) pentalen-2-one prep - from hexachlorocyclopentadiene, and sulphur trioxide with antimony catalyst

Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(e,d) pentalen-2-one (I) is prepared by reacting SO3 with hexachlorocyclopentadiene in a mole ratio of 1.5 and 2 in the presence of Sb (III), Sn (V) halides, oxides or oxyacids as catalyst at 95-120 degrees C, and 50 to 300 psig. The reaction product is hydrolysed with 5 parts wt. aq. caustic alkali at pH >=9 at 85-115 degrees C for >=30 minutes, the pH adjusted to 5-6, with mineral acid, allowed to stand at 85-105 degrees C for 1 hour and the precipitated product (I) covered. (I) is an insecticide, particularly for controlling ants. and roaches. (I) is produced in 95% yields.

Cyclic amino acids and derivatives thereof useful as pharmaceutical agents

The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

Method for Prolonging the Odor of Perfumed Materials

1,168,673. Stabilised perfume compositions. UNIVERSAL OIL PRODUCTS CO. 23 Feb., 1967 [25 Feb., 1966], No. 8679/67. Heading A5B. [Also in Divisions C2 and C5] Perfume compositions such as rose, lavender, rose geranium and eau de Cologne are stabilised against loss of odour by the addition of a compound of the formula: where n is 1 or 2, y is alkyl and x is hydrogen or methyl, with at least three of X's equal methyl, before incorporation into soap compositions.

3A,4,7,7A-Tetrahydro-4-phenylethyl-7a-alkyl-5(6H)-indanones and process for the preparation thereof

Total synthesis of steroids of the estrone and equilenin series involving conjugate 1,4-addition of a meta-substituted benzyl organometallic reagent to a C/D bicyclic methylene ketone. An aromatization of the B-ring of Δ 9(11) estrone derivatives.

Zyklische aminosäuren und deren derivate als arzneimittel

Κυκλικα αμινοξεα και παραγωγα αυτων χρησιμα σαν θepαπευτικοι παραγοντες

Η εφεύρεση είναι μία νέα σειρά κυκλικών αμινοξέων που είναι χρήσιμα στη θεραπεία επιληψίας, προσβολών τάσεων προς λιποθυμία, νευροεκφυλιστικών διαταραχών, κατάθλιψης, άγχους, πανικού, πόνου, νευροπαθολογικών διαταραχών, γαστροεντερικών διαταραχών, όπως συνδρόμου ευερέθιστου εντέρου (IBS) και φλεγμονής, ειδικά αρθρίτιδας. Συμπεριλαμβάνονται μία φαρμακευτική σύνθεση περιέχουσα μία ένωση της εφεύρεσης, καθώς επίσης μέθοδοι παρασκευής των ενώσεων και νέων ενδιαμέσων χρησίμων στη παρασκευή των τελικών ενώσεων.

Methylation of de-A steroids

Treatment of de-A steroids with a methylation agent at extremely low temperatures, i.e., below -50° C. produces corresponding 10β-methyl-Δ 9 (11) -deA steroids with a high 10β to 10α isomer ratio. A number of the product 10β-methyl-Δ 9 (11) -deA steroids are novel compounds. They are useful as intermediates in the synthesis of known medicinally valuable steroids.

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1,230,603. Cyclohexenone derivatives. FARBWERKE HOECHST A.G. 29 July, 1968 [29 July, 1967], No. 36099/68. Heading C2C. A novel compound of Formula I is prepared by reacting 3-(4<SP>1</SP>-oxo-cyclohexyl-4- (3<SP>1</SP>-oxocyclopentyl)-hexane II with 2,2,5,5- tetramethyl - 3,4 - dihydroxy - hexane to give the monoketal III reducing the monoketal to give a mixture of the corresponding epimeric alcohols; treating the latter mixture with dilute mineral acid to remove the ketal group; reacting the resultant 3 - (41 - oxo - cyclohexyl) - 4 - (31 - hydroxycyclopentyl)-hexane with an acylating agent; reacting the resulting 3<SP>1</SP>-acyloxy-cyclopentylderivative with bromine to yield 3-(3<SP>1</SP>-bromo-4<SP>1</SP>- oxo - cyclohexyl) - 4 - (3<SP>1</SP> - acyloxy - cyclopentyl)- hexane; reacting the bromo compound with a lithium halide to give 3-(4<SP>1</SP>-oxo-cyclohexen-2<SP>1</SP>- yl) - 4 - (3<SP>1</SP> - acetoxycyclopentyl) - hexane; and saponifying the latter compound. The starting material II may be prepared by reacting 3 - (41 - hydroxy - cyclohexyl) - 4 - (4<SP>1</SP>- oxo-cyclohexyl)-hexane with acetic anhydride to give 3 - (4<SP>1 </SP>- acetoxy - cyclohexyl) - 4 - (4<SP>1</SP>-oxocyclohexyl)-hexane, oxidizing the latter with CrO 3 to give the compound VIII ring closing compound VIII, using acetic anhydride to give 3-(4<SP>1</SP>-acetoxy-cyclohexyl)-4-(3<SP>1</SP>- oxo-cyclopentyl)-hexane ; saponifying the latter to give the 4<SP>1</SP>-hydroxy-cyclohexyl-derivative and oxidizing the latter with chromium trioxide in pyridine. Pharmaceutical compositions comprise a compound I in admixture with a suitable diluent or carrier, and have androgenic, gestagenic, antiinflammatory and anabolic activity.

Verfahren zur Herstellung von 3-(4'Oxo-cyclohexen-2'-yl)-4-(3'hydroxycyclopentyl)-hexan

10beta-metyl-delta?729?72(?721?721?72)-dea-sterpoder for anvendning sasom mellanprodukter vid framstellning av verdefulla steroider

医学的障害の治療のための一酸化炭素プロドラッグ

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香料としての二置換シクロアルカノン

(57)【要約】 【課題】 芳香剤組成物の調製および該組成物から形成 される製品において有用である芳香性化合物を提供する こと。 【解決手段】 二置換シクロヘキサノンは、２−シクロ ペンチリデンシクロペンタン−１−オン、２−シクロヘ キシリデンシクロヘキサン−１−オン、２−シクロペン チリデンシクロヘキサン−１−オンまたは２−シクロヘ キシリデンシクロペンタン−１−オンの１種から調製さ れる。得られた化合物の芳香特性を分析した。様々な化 合物は、化合物の構造からは予測できない様々な芳香特 性を示した。

Process for producing alicyclic monoketones and process for producing alicyclic diketones

The process for producing alicyclic monoketones (hydroxyphenylcyclohexanone derivatives) according to the present invention comprises hydrogenating substituted bisphenols such as bisphenol A in a solvent in the presence of a palladium/alkali metal catalyst in which palladium and an alkali metal are both supported on a carrier to obtain alicyclic monoketones such as 2-(4-oxocyclohexyl)-2-(4-hydroxyphenyl)propane. The process for producing alicyclic diketones according to the present invention comprises hydrogenating substituted bisphenols such as bisphenol A in a solvent in the presence of a palladium/alkali metal catalyst in which palladium and an alkali metal are both supported on a carrier to obtain alicyclic diketones such as 2,2-bis(4-oxocyclohexyl)propane and 4,4′-bicyclohexanone. The other process for producing alicyclic monoketones according to the present invention comprises hydrogenating biphenols such as bis(4-hydroxyphenyl) in an organic solvent in the presence of a palladium catalyst in which 10 to 30% by weight of palladium is supported on a carrier to obtain alicyclic monoketones such as 4(4′-hydroxyphenyl)cyclohexanone. According to the present invention, alicyclic monoketones or alicyclic diketones can be obtained with high selectivity and in high yields through simple steps, because the process includes only one reaction step to hydrogenate substituted bisphenols under relatively mild conditions.

Verfahren zur herstellung von deasteroiden

香料組成物

(57)【要約】本公報は電子出願前の出願データであるため要約のデータは記録されません。

Pesticidal ketone-malonate adducts

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Verfahren zur Herstellung von 1-gamma-Trimethylammonium-beta-hydroxy-butyramid-d-camphorat

Ketohalogenodimethylperhydrophenanthrenes and process of making same

Malonic acid ester adducts of decachlorooctahydro-1, 3, 4-metheno-2h-cyclobuta (cd)pentalen-2-one

Process for the preparation of dea-steroids

Dimedone derivatives of dialdehydes

A novel class of dimedone derivatives of dialdehydes are useful as antimicrobial agents and fungicides. Their high activity and low toxicity make them candidates for replacements for hexachlorophene.

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Procédé pour combattre les parasites à l'aide d'un nouvel alcool ou d'un de ses dérivés et procédé pour préparer ces composés